acemetacin has been researched along with Osteoarthritis, Knee in 2 studies
acemetacin : A carboxylic ester that is the carboxymethyl ester of indometacin. A non-steroidal anti-inflammatory drug, it is used in the treatment of rheumatoid arthritis, osteoarthritis, and low back pain, as well as for postoperative pain and inflammation. Its activity is due to both acemetacin and its major metabolite, indometacin.
Osteoarthritis, Knee: Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)
| Excerpt | Relevance | Reference |
|---|---|---|
| " As for adverse events, gastrointestinal complaints were dominant in both treatment groups, but significantly more patients interrupted the treatment in the indomethacin group (22." | 2.74 | [Randomized, double blind, multicentre, parallel group study to compare efficacy and safety of acemetacin and indometacin in patients with activated osteoarthrosis of the knee]. ( Gallacchi, G; Hodinka, L, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gallacchi, G | 1 |
| Hodinka, L | 1 |
| Leeb, BF | 1 |
| Bucsi, L | 1 |
| Keszthelyi, B | 1 |
| Böhmova, J | 1 |
| Valesova, M | 1 |
| Hawel, R | 1 |
| Mayrhofer, F | 1 |
| Singer, F | 1 |
| Aglas, F | 1 |
| Bröll, H | 1 |
2 trials available for acemetacin and Osteoarthritis, Knee
| Article | Year |
|---|---|
[Randomized, double blind, multicentre, parallel group study to compare efficacy and safety of acemetacin and indometacin in patients with activated osteoarthrosis of the knee].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Indomethacin; Ma | 2009 |
[Treatment of osteoarthritis of the knee joint. Efficacy and tolerance to acemetacin slow release in comparison to celecoxib].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Confidence Intervals; Data Interpretation | 2004 |