acemetacin has been researched along with Inflammation in 4 studies
acemetacin : A carboxylic ester that is the carboxymethyl ester of indometacin. A non-steroidal anti-inflammatory drug, it is used in the treatment of rheumatoid arthritis, osteoarthritis, and low back pain, as well as for postoperative pain and inflammation. Its activity is due to both acemetacin and its major metabolite, indometacin.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a controlled double blind study the therapeutic efficacy and tolerability of [1-(p-chlorobenzoyl)-5-methoxy-2-methylindol-3-acetoxy] acetic acid (acemetacin, TV 1322, Rantudil¿) and tolmetin were compared in 40 patients suffering from acute and subacute painful irritant conditions in the spinal area and joints." | 5.05 | [Comparison of the therapeutic efficacy and tolerability of acemetacin and tolmetin (author's transl)]. ( Handrich, L, 1980) |
| "Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of acute gout and inflammation." | 3.76 | Acemetacin antinociceptive mechanism is not related to NO or K+ channel pathways. ( Castañeda-Hernández, G; Chávez-Piña, AE; Gil-Flores, M; Ortiz, MI, 2010) |
| "Acemetacin was rapidly converted to indomethacin after its administration." | 1.34 | Mechanisms underlying the anti-inflammatory activity and gastric safety of acemetacin. ( Castañeda-Hernández, G; Chávez-Piña, AE; Dicay, M; McKnight, W; Wallace, JL, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Gil-Flores, M | 1 |
| Ortiz, MI | 1 |
| Castañeda-Hernández, G | 2 |
| Chávez-Piña, AE | 2 |
| McKnight, W | 1 |
| Dicay, M | 1 |
| Wallace, JL | 1 |
| Handrich, L | 1 |
1 trial available for acemetacin and Inflammation
| Article | Year |
|---|---|
[Comparison of the therapeutic efficacy and tolerability of acemetacin and tolmetin (author's transl)].
Topics: Adult; Aged; Anti-Inflammatory Agents; Double-Blind Method; Female; Humans; In Vitro Techniques; Ind | 1980 |
3 other studies available for acemetacin and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Acemetacin antinociceptive mechanism is not related to NO or K+ channel pathways.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Indo | 2010 |
Mechanisms underlying the anti-inflammatory activity and gastric safety of acemetacin.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Biotransfo | 2007 |