acemetacin has been researched along with Ache in 13 studies
acemetacin : A carboxylic ester that is the carboxymethyl ester of indometacin. A non-steroidal anti-inflammatory drug, it is used in the treatment of rheumatoid arthritis, osteoarthritis, and low back pain, as well as for postoperative pain and inflammation. Its activity is due to both acemetacin and its major metabolite, indometacin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Within the framework of a long-term study the efficacy and tolerability of [1-(p-chlorobenzoyl)-5-methoxy-2-methylindol-3-acetoxy] acetic acid (acemetacin, TV 1322, Rantudil) were tested in 26 female patients suffering from rheumatoid arthritis." | 7.66 | [Results of a long-term study with acemetacin in the therapy of patients suffering from rheumatoid arthritis (author's transl)]. ( Eberl, R; Heiter, A; Tausch, G, 1980) |
| "Acemetacin was tested in an open clinical study with regard to occurrence and duration of its analgesic effect to 20 patients suffering from arthrosis of the hip and knee joint." | 5.27 | [Acemetacin in the treatment of painful arthroses. Results of an open short-term study on the starting point of the analgesic effect and its duration]. ( Bröll, H; Schragl, F; Siegmeth, W, 1984) |
| "In a double blind study [1-(p-chlorobenzoyl)-5-methoxy-2-methylindol-3-acetoxy] acetic acid (acemetacin, TV 1322, Rantudil¿) was compared with indometacin in 2 x 20 patients suffering from rheumatoid arthritis." | 5.05 | [Controlled double blind comparison of acemetacin to indomethacin in patients with chronic polyarthritis]. ( Eberl, R; Heiter, A; Tausch, G, 1980) |
| "In a controlled double blind study the therapeutic efficacy and tolerability of [1-(p-chlorobenzoyl)-5-methoxy-2-methylindol-3-acetoxy] acetic acid (acemetacin, TV 1322, Rantudil¿) and tolmetin were compared in 40 patients suffering from acute and subacute painful irritant conditions in the spinal area and joints." | 5.05 | [Comparison of the therapeutic efficacy and tolerability of acemetacin and tolmetin (author's transl)]. ( Handrich, L, 1980) |
| "Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of acute gout and inflammation." | 3.76 | Acemetacin antinociceptive mechanism is not related to NO or K+ channel pathways. ( Castañeda-Hernández, G; Chávez-Piña, AE; Gil-Flores, M; Ortiz, MI, 2010) |
| "Within the framework of a long-term study the efficacy and tolerability of [1-(p-chlorobenzoyl)-5-methoxy-2-methylindol-3-acetoxy] acetic acid (acemetacin, TV 1322, Rantudil) were tested in 26 female patients suffering from rheumatoid arthritis." | 3.66 | [Results of a long-term study with acemetacin in the therapy of patients suffering from rheumatoid arthritis (author's transl)]. ( Eberl, R; Heiter, A; Tausch, G, 1980) |
| "Acemetacin has shown that its analgesic, anti-inflammatory and antipyretic effects are equal to those of the reference substance, indometacin." | 2.65 | [Clinical trials with acemetacin on children and adolescents (author's transl)]. ( Neugirg, R; Penners, R, 1980) |
| "Acemetacin was tested in an open clinical study with regard to occurrence and duration of its analgesic effect to 20 patients suffering from arthrosis of the hip and knee joint." | 1.27 | [Acemetacin in the treatment of painful arthroses. Results of an open short-term study on the starting point of the analgesic effect and its duration]. ( Bröll, H; Schragl, F; Siegmeth, W, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (53.85) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, JM | 1 |
| Liu, KC | 1 |
| Yeh, WL | 1 |
| Chen, JC | 1 |
| Liu, SJ | 1 |
| Uncu, H | 1 |
| Gil-Flores, M | 1 |
| Ortiz, MI | 1 |
| Castañeda-Hernández, G | 1 |
| Chávez-Piña, AE | 1 |
| Bori Segura, G | 1 |
| Torres y Gutierrez Rubio, A | 1 |
| Herrera Gómez, LE | 1 |
| Olguín Uribe, J | 1 |
| Leeb, BF | 1 |
| Bucsi, L | 1 |
| Keszthelyi, B | 1 |
| Böhmova, J | 1 |
| Valesova, M | 1 |
| Hawel, R | 1 |
| Mayrhofer, F | 1 |
| Singer, F | 1 |
| Aglas, F | 1 |
| Bröll, H | 2 |
| Siegmeth, W | 1 |
| Schragl, F | 1 |
| Heiter, A | 2 |
| Tausch, G | 2 |
| Eberl, R | 2 |
| Kronhagel, R | 1 |
| Handrich, L | 1 |
| Neugirg, R | 1 |
| Penners, R | 1 |
| Dold, U | 1 |
| Blumberger, W | 1 |
| Toda, Y | 1 |
| Kobayashi, T | 1 |
8 trials available for acemetacin and Ache
| Article | Year |
|---|---|
A comparison of low-molecular-weight heparin and combined therapy of low-molecular-weight heparin with an anti-inflammatory agent in the treatment of superficial vein thrombosis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; | 2009 |
Efficacy and tolerability of acemetacin, a non-steroidal anti-inflammatory drug, in Mexican patients: result of the ETAPAM Study.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Athletic Injuries; Female; Humans; Indomethaci | 2002 |
[Treatment of osteoarthritis of the knee joint. Efficacy and tolerance to acemetacin slow release in comparison to celecoxib].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Confidence Intervals; Data Interpretation | 2004 |
[Controlled double blind comparison of acemetacin to indomethacin in patients with chronic polyarthritis].
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chronic Disease; Double-Blind Method; | 1980 |
[Clinical results of a double blind study with the new antirheumatic agent acemetacin (author's transl)].
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis; Double-Blind Method; Drug Evaluation; Female; Huma | 1980 |
[Comparison of the therapeutic efficacy and tolerability of acemetacin and tolmetin (author's transl)].
Topics: Adult; Aged; Anti-Inflammatory Agents; Double-Blind Method; Female; Humans; In Vitro Techniques; Ind | 1980 |
[Clinical trials with acemetacin on children and adolescents (author's transl)].
Topics: Adolescent; Anti-Inflammatory Agents; Body Temperature; Child; Child, Preschool; Double-Blind Method | 1980 |
The usefulness of walking for preventing sarcopenia in dieting postmenopausal women complaining of knee pain.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Appetite Depressants; Body Composition; Combined Moda | 2000 |
5 other studies available for acemetacin and Ache
| Article | Year |
|---|---|
Sustained Release of Levobupivacaine, Lidocaine, and Acemetacin from Electrosprayed Microparticles: In Vitro and In Vivo Studies.
Topics: 3T3 Cells; Analgesics; Animals; Delayed-Action Preparations; Disease Models, Animal; Drug Compoundin | 2020 |
Acemetacin antinociceptive mechanism is not related to NO or K+ channel pathways.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Indo | 2010 |
[Acemetacin in the treatment of painful arthroses. Results of an open short-term study on the starting point of the analgesic effect and its duration].
Topics: Analgesia; Arthritis; Female; Humans; Indomethacin; Male; Pain; Physical Exertion; Rest; Time Factor | 1984 |
[Therapy of acute attacks of gout using acemetacin (author's transl)].
Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents; Female; Gout; Humans; Indoleacetic Acids; Indo | 1980 |
[Results of a long-term study with acemetacin in the therapy of patients suffering from rheumatoid arthritis (author's transl)].
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chronic Disease; Female; Humans; Indol | 1980 |