Page last updated: 2024-08-17

acedapsone and Leprosy

acedapsone has been researched along with Leprosy in 17 studies

*Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid. [MeSH]

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199012 (70.59)18.7374
1990's1 (5.88)18.2507
2000's2 (11.76)29.6817
2010's1 (5.88)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Bera, S; Mondal, D1
George, J1
Christian, M; Jesudasan, K; Kurian, N; Rao, GS; Shaw, IN1
Ellard, GA1
Keeler, RF1
Neelan, PN; Noordeen, SK; Sivaprasad, N1
Munaf, A; Neelan, PN; Noordeen, SK1
Desikan, KV; Ramu, G; Sengupta, U1
Blanc, LJ1
Smith, CM; Smith, WC1
Fasal, P; Jano, B; Russell, DA; Shepard, CC; Worth, RM2
Anand, LC; Rathore, BS1
Levy, L; Peters, JH1
Gordon, GR; Levy, L; Murray, JF; Peters, JH; Russell, DA; Scott, GC; Shepard, CC; Vincin, DR1
Iyer, CG; Ramanujam, K; Ramu, G1
Levy, L; Shepard, CC1

Reviews

3 review(s) available for acedapsone and Leprosy

ArticleYear
Insights of synthetic analogues of anti-leprosy agents.
    Bioorganic & medicinal chemistry, 2019, 07-01, Volume: 27, Issue:13

    Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship

2019
Metabolism and interactions of antileprosy drugs.
    Biochemical pharmacology, 2020, Volume: 177

    Topics: Acedapsone; Biological Availability; Biotransformation; Clofazimine; Cytochrome P-450 CYP3A; Dapsone; Drug Interactions; Drug Therapy, Combination; Half-Life; Humans; Leprostatic Agents; Leprosy; Metabolic Clearance Rate; Metabolic Networks and Pathways; Mycobacterium leprae; Rifampin

2020
Chemoprophylaxis is effective in the prevention of leprosy in endemic countries: a systematic review and meta-analysis. MILEP2 Study Group. Mucosal Immunology of Leprosy.
    The Journal of infection, 2000, Volume: 41, Issue:2

    Topics: Acedapsone; Clinical Trials as Topic; Cost-Benefit Analysis; Dapsone; Humans; Leprostatic Agents; Leprosy; Rifampin; Risk Factors; Topography, Medical

2000

Trials

6 trial(s) available for acedapsone and Leprosy

ArticleYear
Multidrug therapy for leprosy in Trinidad and Tobago: a preliminary report.
    Leprosy review, 1984, Volume: 55, Issue:4

    Topics: Acedapsone; Adolescent; Adult; Aged; Child; Child, Preschool; Clinical Trials as Topic; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Leprosy; Male; Middle Aged; Rifampin; Trinidad and Tobago

1984
Chemoprophylaxis against leprosy with acedapsone.
    The Indian journal of medical research, 1983, Volume: 78

    Topics: Acedapsone; Adolescent; Age Factors; Child; Child, Preschool; Dapsone; Female; Humans; Infant; Leprosy; Male; Sex Factors

1983
Chemoprophylaxis against leprosy with acedapsone. An interim report.
    Leprosy in India, 1980, Volume: 52, Issue:1

    Topics: Acedapsone; Adolescent; Age Factors; Child; Child, Preschool; Clinical Trials as Topic; Dapsone; Double-Blind Method; Female; Humans; India; Infant; Leprosy; Male; Time Factors

1980
Susceptibility of Mycobacterium leprae to dapsone as a determinant of patient response to acedapsone.
    Antimicrobial agents and chemotherapy, 1976, Volume: 9, Issue:1

    Topics: Acedapsone; Animals; Clinical Trials as Topic; Dapsone; Humans; Injections, Intramuscular; Leprosy; Mice; Mycobacterium leprae; Time Factors

1976
A preliminary report on a therapeutic trial with acedapsone in lepromatous leprosy.
    Leprosy review, 1975, Volume: 46, Issue:2 Suppl

    Topics: Acedapsone; Adult; Clinical Trials as Topic; Dapsone; Humans; Leprosy; Male

1975
The number of Mycobacterium leprae in the pretreatment biopsy-specimen does not determine the rate of response of patients with lepromatous leprosy to chemotherapy with acedapsone.
    Leprosy review, 1986, Volume: 57, Issue:1

    Topics: Acedapsone; Animals; Clinical Trials as Topic; Dapsone; Drug Evaluation; Humans; Leprosy; Mice; Mycobacterium leprae; Random Allocation; Skin

1986

Other Studies

8 other study(ies) available for acedapsone and Leprosy

ArticleYear
Effectiveness of multidrug therapy in multibacillary leprosy: a long-term follow-up of 34 multibacillary leprosy patients treated with multidrug regimens till skin smear negativity.
    Leprosy review, 2003, Volume: 74, Issue:2

    Topics: Acedapsone; Adult; Clofazimine; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leprostatic Agents; Leprosy; Male; Rifampin; Skin; Treatment Outcome; World Health Organization

2003
Combined treatment for lepromatous leprosy.
    Leprosy review, 1980, Volume: 51, Issue:3

    Topics: Acedapsone; Animals; Dapsone; Drug Therapy, Combination; Ethionamide; Humans; Leprostatic Agents; Leprosy; Mice; Prothionamide; Rifampin; Thioacetazone

1980
Influence of sulphone therapy on lepromin reaction.
    Leprosy review, 1980, Volume: 51, Issue:3

    Topics: Acedapsone; Adult; Dapsone; Humans; Lepromin; Leprosy

1980
Trials of preventive therapy.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1999, Volume: 67, Issue:4 Suppl

    Topics: Acedapsone; Chemoprevention; Clinical Trials as Topic; Dapsone; Humans; India; Leprostatic Agents; Leprosy; Pacific Islands; Rifampin

1999
Letter: Prevention of leprosy by acedapsone.
    Lancet (London, England), 1975, Oct-18, Volume: 2, Issue:7938

    Topics: Acedapsone; Adult; Child; Dapsone; Humans; Leprosy; Micronesia

1975
Acedapsone in the prevention of leprosy: field trial in three high prevalence villages in Micronesia.
    The American journal of tropical medicine and hygiene, 1979, Volume: 28, Issue:3

    Topics: Acedapsone; Adult; Child; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Micronesia; Patient Compliance; Recurrence

1979
Activity and effective serum level of repository sulphones (DADDS) in lepromatous leprosy.
    Leprosy in India, 1979, Volume: 51, Issue:3

    Topics: Acedapsone; Adult; Dapsone; Delayed-Action Preparations; Female; Humans; Injections, Intramuscular; Leprosy; Male; Middle Aged

1979
Acedapsone treatment of leprosy patients: response versus drug disposition.
    The American journal of tropical medicine and hygiene, 1977, Volume: 26, Issue:1

    Topics: Acedapsone; Acetylation; Adult; Child; Dapsone; Female; Humans; Leprosy; Male; Phenotype; Sulfamethazine

1977