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acecainide and Tachyarrhythmia

acecainide has been researched along with Tachyarrhythmia in 18 studies

Acecainide: A major metabolite of PROCAINAMIDE. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure.
N-acetylprocainamide : A benzamide obtained via formal condensation of 4-acetamidobenzoic acid and 2-(diethylamino)ethylamine.

Research Excerpts

ExcerptRelevanceReference
"Antiarrhythmic properties of N-acetylprocainamide (NAPA), an active metabolite of procainamide, were studied in 12 patients with coronary artery disease who presented with cardiac arrest or documented sustained ventricular tachycardia (VT)."7.67Electrophysiologic evaluation of the antiarrhythmic effects of N-acetylprocainamide for ventricular tachycardia secondary to coronary artery disease. ( Flowers, D; Keefe, D; Miura, DS; Somberg, JC; Torres, V; Williams, S; Wynn, J, 1985)
"Antiarrhythmic properties of N-acetylprocainamide, an active metabolite of procainamide, were studied in 15 patients who presented with a cardiac arrest or documented sustained ventricular tachycardia."7.67N-acetylprocainamide's antiarrhythmic action in patients with ventricular tachycardia. ( Keefe, D; Miura, D; Somberg, J; Torres, V; Williams, S; Wynn, J, 1986)
"Twenty Caucasian adult patients with ventricular tachycardia were treated with intravenous procainamide."7.67Influence of age, renal function and heart failure on procainamide clearance and n-acetylprocainamide serum concentrations. ( Bauer, LA; Black, D; Gensler, A; Sprinkle, J, 1989)
"N-Acetylprocainamide (NAPA), a class III antiarrhythmic drug, caused torsade de pointes in a 72 year old woman who had this arrhythmia on two previous occasions while being treated with quinidine and disopyramide."3.67Torsade de pointes induced by N-acetylprocainamide. ( Asada, A; Atkinson, AJ; Bowsher, DJ; Chow, MJ; Kushner, W; Murphy, JJ; Piergies, AA; Ruo, TI; Talano, JV, 1984)
"Antiarrhythmic properties of N-acetylprocainamide (NAPA), an active metabolite of procainamide, were studied in 12 patients with coronary artery disease who presented with cardiac arrest or documented sustained ventricular tachycardia (VT)."3.67Electrophysiologic evaluation of the antiarrhythmic effects of N-acetylprocainamide for ventricular tachycardia secondary to coronary artery disease. ( Flowers, D; Keefe, D; Miura, DS; Somberg, JC; Torres, V; Williams, S; Wynn, J, 1985)
"Quinidine therapy is one of the most common causes of the acquired long QT syndrome and the morphologically distinctive tachyarrhythmia torsade de pointes."3.67Clinical features and basic mechanisms of quinidine-induced arrhythmias. ( Hoffman, BF; Roden, DM; Thompson, KA; Woosley, RL, 1986)
"Antiarrhythmic properties of N-acetylprocainamide, an active metabolite of procainamide, were studied in 15 patients who presented with a cardiac arrest or documented sustained ventricular tachycardia."3.67N-acetylprocainamide's antiarrhythmic action in patients with ventricular tachycardia. ( Keefe, D; Miura, D; Somberg, J; Torres, V; Williams, S; Wynn, J, 1986)
"Twenty Caucasian adult patients with ventricular tachycardia were treated with intravenous procainamide."3.67Influence of age, renal function and heart failure on procainamide clearance and n-acetylprocainamide serum concentrations. ( Bauer, LA; Black, D; Gensler, A; Sprinkle, J, 1989)
"Nineteen patients whose arrhythmias were initially suppressed with acetylprocainamide underwent long-term treatment with this drug."3.66Long-term antiarrhythmic therapy with acetylprocainamide. ( Drayer, DE; Kluger, J; Leech, S; Lloyd, V; Reidenberg, MM, 1981)
"A 66-year-old female with chronic renal failure received five doses of procainamide and developed marked QT interval prolongation and recurrent episodes of torsades de pointes, which were temporally related to high serum n-acetylprocainamide (NAPA) levels and not to procainamide levels."1.27Torsades de pointes due to n-acetylprocainamide. ( Stevenson, WG; Weiss, J, 1985)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199018 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kluger, J1
Leech, S1
Reidenberg, MM1
Lloyd, V1
Drayer, DE1
Engel, TR1
Olshansky, B1
Martins, J1
Hunt, S1
Sung, RJ1
Juma, Z1
Saksena, S1
Chow, MJ1
Piergies, AA1
Bowsher, DJ1
Murphy, JJ1
Kushner, W1
Ruo, TI1
Asada, A1
Talano, JV1
Atkinson, AJ1
Marchlinski, FE1
Buxton, AE1
Vassallo, JA1
Waxman, HL1
Cassidy, DM1
Doherty, JU1
Josephson, ME1
Stevenson, WG1
Weiss, J1
Wynn, J2
Miura, DS1
Torres, V2
Flowers, D1
Keefe, D2
Williams, S2
Somberg, JC1
Nguyen, KP1
Thomsen, G1
Liem, B1
Swerdlow, CD1
Franz, MR1
Roden, DM2
Thompson, KA1
Hoffman, BF1
Woosley, RL2
Borkan, SC1
Morady, F1
DiCarlo, LA1
de Buitleir, M1
Krol, RB1
Baerman, JM1
Kou, WH1
Somberg, J1
Miura, D1
Fujii, T1
Ohe, T1
Deguchi, F1
Shimomura, K1
Ito, K1
Bauer, LA1
Black, D1
Gensler, A1
Sprinkle, J1
Stratmann, HG1
Walter, KE1
Kennedy, HL1
Herre, JM1
Thompson, JA1

Reviews

1 review available for acecainide and Tachyarrhythmia

ArticleYear
The electropharmacology of acute drug testing using pacemakers.
    Pacing and clinical electrophysiology : PACE, 1982, Volume: 5, Issue:4

    Topics: Acecainide; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Electrophysiology; Heart Co

1982

Other Studies

17 other studies available for acecainide and Tachyarrhythmia

ArticleYear
Long-term antiarrhythmic therapy with acetylprocainamide.
    The American journal of cardiology, 1981, Volume: 48, Issue:6

    Topics: Acecainide; Acetylation; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Arthritis, Rheum

1981
N-acetyl procainamide causing torsades de pointes.
    The American journal of cardiology, 1982, Volume: 50, Issue:6

    Topics: Acecainide; Aged; Anti-Arrhythmia Agents; Drug Therapy, Combination; Electrocardiography; Female; Hu

1982
Electrophysiologic properties and antiarrhythmic mechanisms of intravenous N-acetylprocainamide in patients with ventricular dysrhythmias.
    American heart journal, 1983, Volume: 105, Issue:5

    Topics: Acecainide; Adult; Aged; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Cardiac Pacing, Artific

1983
Torsade de pointes induced by N-acetylprocainamide.
    Journal of the American College of Cardiology, 1984, Volume: 4, Issue:3

    Topics: Acecainide; Aged; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Kinetics; Procainamide;

1984
Comparative electrophysiologic effects of intravenous and oral procainamide in patients with sustained ventricular arrhythmias.
    Journal of the American College of Cardiology, 1984, Volume: 4, Issue:6

    Topics: Acecainide; Administration, Oral; Adult; Aged; Cardiac Pacing, Artificial; Electrophysiology; Female

1984
Torsades de pointes due to n-acetylprocainamide.
    Pacing and clinical electrophysiology : PACE, 1985, Volume: 8, Issue:4

    Topics: Acecainide; Aged; Female; Humans; Kidney Failure, Chronic; Procainamide; Renal Dialysis; Tachycardia

1985
Electrophysiologic evaluation of the antiarrhythmic effects of N-acetylprocainamide for ventricular tachycardia secondary to coronary artery disease.
    The American journal of cardiology, 1985, Nov-15, Volume: 56, Issue:13

    Topics: Acecainide; Aged; Coronary Disease; Electrocardiography; Electrophysiology; Female; Heart Arrest; He

1985
N-acetylprocainamide, torsades de pointes, and hemodialysis.
    Annals of internal medicine, 1986, Volume: 104, Issue:2

    Topics: Acecainide; Adult; Female; Glomerulonephritis; Humans; Procainamide; Renal Dialysis; Tachycardia

1986
Clinical features and basic mechanisms of quinidine-induced arrhythmias.
    Journal of the American College of Cardiology, 1986, Volume: 8, Issue:1 Suppl A

    Topics: Acecainide; Action Potentials; Animals; Bradycardia; Dogs; Dose-Response Relationship, Drug; Humans;

1986
Hemoperfusion for N-acetylprocainamide intoxication.
    Annals of internal medicine, 1986, Volume: 105, Issue:6

    Topics: Acecainide; Hemoperfusion; Humans; Procainamide; Tachycardia

1986
Effects of incremental doses of procainamide on ventricular refractoriness, intraventricular conduction, and induction of ventricular tachycardia.
    Circulation, 1986, Volume: 74, Issue:6

    Topics: Acecainide; Aged; Cardiac Catheterization; Cardiac Pacing, Artificial; Dose-Response Relationship, D

1986
N-acetylprocainamide's antiarrhythmic action in patients with ventricular tachycardia.
    Angiology, 1986, Volume: 37, Issue:12 Pt 2

    Topics: Acecainide; Drug Evaluation; Electric Stimulation; Heart Ventricles; Humans; Infusions, Intravenous;

1986
[A case of torsade de pointes induced by N-acetyl procainamide].
    Kokyu to junkan. Respiration & circulation, 1987, Volume: 35, Issue:2

    Topics: Acecainide; Humans; Male; Middle Aged; Procainamide; Tachycardia

1987
Influence of age, renal function and heart failure on procainamide clearance and n-acetylprocainamide serum concentrations.
    International journal of clinical pharmacology, therapy, and toxicology, 1989, Volume: 27, Issue:5

    Topics: Acecainide; Aged; Aging; Creatinine; Female; Heart Failure; Humans; Kidney; Kidney Diseases; Male; M

1989
Torsade de pointes associated with elevated N-acetylprocainamide levels.
    American heart journal, 1985, Volume: 109, Issue:2

    Topics: Acecainide; Humans; Male; Middle Aged; Procainamide; Tachycardia

1985
QT prolongation and arrhythmia suppression.
    American heart journal, 1985, Volume: 109, Issue:2

    Topics: Acecainide; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Deafness; Death, Sudden; Elect

1985
Polymorphic ventricular tachycardia and ventricular fibrillation due to N-acetyl procainamide.
    The American journal of cardiology, 1985, Jan-01, Volume: 55, Issue:1

    Topics: Acecainide; Aged; Electrocardiography; Heart Ventricles; Humans; Male; Procainamide; Tachycardia; Ve

1985