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acecainide and Myocardial Infarction

acecainide has been researched along with Myocardial Infarction in 4 studies

Acecainide: A major metabolite of PROCAINAMIDE. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure.
N-acetylprocainamide : A benzamide obtained via formal condensation of 4-acetamidobenzoic acid and 2-(diethylamino)ethylamine.

Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).

Research Excerpts

ExcerptRelevanceReference
" This study evaluated the influence of infarct healing on the electrophysiologic effects of procainamide (PA) and N-acetylprocainamide (NAPA) in a sedated, closed-chest canine model with a healing anterior wall myocardial infarction, indwelling myocardial electrodes and inducible sustained ventricular tachyarrhythmias (VT)."3.69The discordant influences of infarct healing on the electrophysiologic effects of procainamide and N-acetylprocainamide. ( Coyne, KS; Meimer, J; Nelson, SD, 1995)
"The pharmacokinetics and development of antinuclear antibodies (ANAs) during procainamide (PA) therapy were studied in 35 patients with ventricular arrhythmias."3.66Significance of acetylator phenotype in pharmacokinetics and adverse effects of procainamide. ( Leskinen, O; Metsä-Ketelä, T; Ruosteenoja, R; Ylitalo, P, 1983)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Engel, TR1
Ylitalo, P1
Ruosteenoja, R1
Leskinen, O1
Metsä-Ketelä, T1
Nelson, SD1
Coyne, KS1
Meimer, J1
Roden, DM1

Reviews

1 review available for acecainide and Myocardial Infarction

ArticleYear
The electropharmacology of acute drug testing using pacemakers.
    Pacing and clinical electrophysiology : PACE, 1982, Volume: 5, Issue:4

    Topics: Acecainide; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Electrophysiology; Heart Co

1982

Other Studies

3 other studies available for acecainide and Myocardial Infarction

ArticleYear
Significance of acetylator phenotype in pharmacokinetics and adverse effects of procainamide.
    European journal of clinical pharmacology, 1983, Volume: 25, Issue:6

    Topics: Acecainide; Acetylation; Adult; Aged; Antibodies, Antinuclear; Arrhythmias, Cardiac; Delayed-Action

1983
The discordant influences of infarct healing on the electrophysiologic effects of procainamide and N-acetylprocainamide.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:1

    Topics: Acecainide; Animals; Dogs; Electrophysiology; Heart; Heart Conduction System; Myocardial Infarction;

1995
Antiarrhythmic drugs. Clinical pharmacology of the old and the new agents.
    Postgraduate medicine, 1985, Sep-15, Volume: 78, Issue:4

    Topics: Acecainide; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death, Sudden; Delayed-Action

1985