acecainide has been researched along with Libman-Sacks Disease in 15 studies
Acecainide: A major metabolite of PROCAINAMIDE. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure.
N-acetylprocainamide : A benzamide obtained via formal condensation of 4-acetamidobenzoic acid and 2-(diethylamino)ethylamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Procainamide (PA) has been a mainstay of treatment against acute and chronic supraventricular and ventricular arrhythmias for more than 30 years." | 8.76 | Procainamide: clinical pharmacology and efficacy against ventricular arrhythmias. ( Giardina, EG, 1984) |
| "Procainamide hydrochloride-induced thrombocytopenia has infrequently been reported in the past." | 7.67 | Thrombocytopenia following sustained-release procainamide. ( Carlson, RJ; Gottlieb, AJ; Meisner, DJ, 1985) |
| "Procainamide (PA) has been a mainstay of treatment against acute and chronic supraventricular and ventricular arrhythmias for more than 30 years." | 4.76 | Procainamide: clinical pharmacology and efficacy against ventricular arrhythmias. ( Giardina, EG, 1984) |
| "Procainamide hydrochloride-induced thrombocytopenia has infrequently been reported in the past." | 3.67 | Thrombocytopenia following sustained-release procainamide. ( Carlson, RJ; Gottlieb, AJ; Meisner, DJ, 1985) |
| "To assess the efficacy, plasma drug concentrations and adverse effects of a new sustained release preparation of procainamide, 33 patients with heart disease were studied in an acute dose-ranging protocol and a chronic treatment protocol." | 1.26 | Efficacy, plasma concentrations and adverse effects of a new sustained release procainamide preparation. ( Bigger, JT; Fenster, PE; Giardina, EG; Marcus, FI; Mayersohn, M; Perrier, D, 1980) |
| "These data suggest that systemic lupus erythematosus and procainamide-induced lupus may differ in the relative reversibility of a regulatory defect associated with a Con A responsive population of peripheral blood mononuclear (PBM) cells." | 1.26 | Inhibition of Con A mitogenesis by serum from procainamide-treated patients and patients with systemic lupus erythematosus. ( Cunningham-Rundles, S; Tannen, RH, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (93.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giardina, EG | 2 |
| Ahmad, S | 1 |
| Fenster, PE | 1 |
| Bigger, JT | 1 |
| Mayersohn, M | 1 |
| Perrier, D | 1 |
| Marcus, FI | 1 |
| González, ER | 1 |
| Reidenberg, MM | 4 |
| Uetrecht, JP | 1 |
| Freeman, RW | 1 |
| Woosley, RL | 1 |
| Tannen, RH | 1 |
| Cunningham-Rundles, S | 1 |
| Tanaka, K | 1 |
| Bernstein, RE | 1 |
| Lahita, R | 1 |
| Kluger, J | 1 |
| Drayer, DE | 2 |
| Koffler, D | 1 |
| Sonnhag, C | 1 |
| Karlsson, E | 1 |
| Hed, J | 1 |
| Zacharias, W | 1 |
| Koopman, WJ | 1 |
| Meisner, DJ | 1 |
| Carlson, RJ | 1 |
| Gottlieb, AJ | 1 |
1 review available for acecainide and Libman-Sacks Disease
| Article | Year |
|---|---|
Procainamide: clinical pharmacology and efficacy against ventricular arrhythmias.
Topics: Acecainide; Administration, Oral; Animals; Arrhythmias, Cardiac; Electrocardiography; Heart; Humans; | 1984 |
14 other studies available for acecainide and Libman-Sacks Disease
| Article | Year |
|---|---|
Procainamide, NAPA and systemic lupus.
Topics: Acecainide; Animals; Dogs; Humans; Lupus Erythematosus, Systemic; Procainamide | 1980 |
Efficacy, plasma concentrations and adverse effects of a new sustained release procainamide preparation.
Topics: Acecainide; Acetylation; Adult; Aged; Anti-Arrhythmia Agents; Antibodies, Antinuclear; Arrhythmias, | 1980 |
Alter drug structure--avert induced lupus.
Topics: Acecainide; Arrhythmias, Cardiac; Female; Humans; Lupus Erythematosus, Systemic; Male; Procainamide; | 1981 |
The chemical induction of systemic lupus erythematosus and lupus-like illnesses.
Topics: Acecainide; Acetylation; Adult; Female; Humans; Hydralazine; Hydrazines; Isoniazid; Lupus Erythemato | 1981 |
The implications of procainamide metabolism to its induction of lupus.
Topics: Acecainide; Acetylation; Animals; Antibodies, Antinuclear; Antibody Formation; Humans; Hydroxylamine | 1981 |
Inhibition of Con A mitogenesis by serum from procainamide-treated patients and patients with systemic lupus erythematosus.
Topics: Acecainide; Antibodies; Binding, Competitive; Concanavalin A; Humans; Immunoglobulin G; In Vitro Tec | 1982 |
Aromatic amines and the pathogenesis of lupus erythematosus.
Topics: Acecainide; Acetylation; Amines; Anti-Arrhythmia Agents; Humans; Hydrazines; Lupus Erythematosus, Sy | 1983 |
A study of intrinsic and extrinsic factors in the development of systemic lupus erythematosus.
Topics: Acecainide; Antigen-Antibody Complex; Humans; Lupus Erythematosus, Systemic; Lymphocyte Activation | 1984 |
Procainamide, acetylprocainamide, and drug-induced lupus erythematosus.
Topics: Acecainide; Humans; Immune Complex Diseases; Lupus Erythematosus, Systemic; Procainamide | 1979 |
Antibodies to nuclear antigens in patients treated with procainamide or acetylprocainamide.
Topics: Acecainide; Aged; Antibodies, Antinuclear; Antibody Formation; Cell Nucleus; DNA; DNA, Single-Strand | 1979 |
Procainamide-induced lupus erythematosus-like syndrome in relation to acetylator phenotype and plasma levels of procainamide.
Topics: Acecainide; Acetylation; Adult; Aged; Antibodies, Antinuclear; Female; Humans; Isoniazid; Lupus Eryt | 1979 |
Lupus-inducing drugs alter the structure of supercoiled circular DNA domains.
Topics: Acecainide; Animals; Antibodies; Canavanine; DNA, Superhelical; Electrophoresis, Agar Gel; Escherich | 1990 |
Procainamide, N-acetylprocainamide, antinuclear antibody and systemic lupus erythematosus.
Topics: Acecainide; Acetylation; Antibodies, Antinuclear; Humans; Lupus Erythematosus, Systemic; Procainamid | 1986 |
Thrombocytopenia following sustained-release procainamide.
Topics: Acecainide; Acetylation; Adult; Aged; Antibodies, Antinuclear; Delayed-Action Preparations; Humans; | 1985 |