acecainide has been researched along with Kidney Failure, Chronic in 8 studies
Acecainide: A major metabolite of PROCAINAMIDE. Its anti-arrhythmic action may cause cardiac toxicity in kidney failure.
N-acetylprocainamide : A benzamide obtained via formal condensation of 4-acetamidobenzoic acid and 2-(diethylamino)ethylamine.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two patients with chronic renal failure developed transient sinus node dysfunction requiring insertion of a temporary pacemaker while receiving procainamide to control ventricular arrhythmias." | 3.66 | Procainamide-induced sinus node dysfunction in patients with chronic renal failure. ( Friedman, HS; Kim, HG, 1979) |
| "A 66-year-old female with chronic renal failure received five doses of procainamide and developed marked QT interval prolongation and recurrent episodes of torsades de pointes, which were temporally related to high serum n-acetylprocainamide (NAPA) levels and not to procainamide levels." | 1.27 | Torsades de pointes due to n-acetylprocainamide. ( Stevenson, WG; Weiss, J, 1985) |
| " The procainamide elimination half-life ranged from 6." | 1.27 | Procainamide pharmacokinetics in patients on continuous ambulatory peritoneal dialysis. ( Beirne, GJ; Moorthy, AV; Raehl, CL, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Raja, R | 1 |
| Kramer, M | 1 |
| Alvis, R | 1 |
| Goldstein, S | 1 |
| DeLosAngeles, A | 1 |
| Basseches, PJ | 1 |
| DiGregorio, GJ | 1 |
| Stec, GP | 1 |
| Atkinson, AJ | 1 |
| Nevin, MJ | 1 |
| Thenot, JP | 1 |
| Ruo, TI | 1 |
| Gibson, TP | 1 |
| Ivanovich, P | 1 |
| del Greco, F | 1 |
| Kim, HG | 1 |
| Friedman, HS | 1 |
| Stevenson, WG | 1 |
| Weiss, J | 1 |
| Braden, GL | 1 |
| Fitzgibbons, JP | 1 |
| Germain, MJ | 1 |
| Ledewitz, HM | 1 |
| Raehl, CL | 1 |
| Moorthy, AV | 1 |
| Beirne, GJ | 1 |
| Sica, DA | 1 |
| Yonce, C | 1 |
| Small, R | 1 |
| Cefali, E | 1 |
| Harford, A | 1 |
| Poynor, W | 1 |
8 other studies available for acecainide and Kidney Failure, Chronic
| Article | Year |
|---|---|
Resin hemoperfusion for severe N-acetylprocainamide toxicity in patients with renal failure.
Topics: Acecainide; Aged; Arrhythmias, Cardiac; Female; Hemoperfusion; Humans; Kidney Failure, Chronic; Male | 1984 |
Excretion of procainamide into bile and saliva in rats with chronic renal failure.
Topics: Acecainide; Animals; Bile; Kidney Failure, Chronic; Male; Procainamide; Rats; Rats, Inbred Strains; | 1982 |
N-Acetylprocainamide pharmacokinetics in functionally anephric patients before and after perturbation by hemodialysis.
Topics: Acecainide; Adult; Computers; Female; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; | 1979 |
Procainamide-induced sinus node dysfunction in patients with chronic renal failure.
Topics: Acecainide; Aged; Angina Pectoris; Arrhythmia, Sinus; Arrhythmias, Cardiac; Bradycardia; Female; Hea | 1979 |
Torsades de pointes due to n-acetylprocainamide.
Topics: Acecainide; Aged; Female; Humans; Kidney Failure, Chronic; Procainamide; Renal Dialysis; Tachycardia | 1985 |
Hemoperfusion for treatment of N-acetylprocainamide intoxication.
Topics: Acecainide; Hemoperfusion; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Procainamid | 1986 |
Procainamide pharmacokinetics in patients on continuous ambulatory peritoneal dialysis.
Topics: Acecainide; Adult; Aged; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Pe | 1986 |
Pharmacokinetics of procainamide in continuous ambulatory peritoneal dialysis.
Topics: Acecainide; Adult; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis, | 1988 |