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acebutolol and Pregnancy

acebutolol has been researched along with Pregnancy in 18 studies

Acebutolol: A cardioselective beta-1 adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm, as well as weak inherent sympathomimetic action.
acebutolol : An ether that is the 2-acetyl-4-(butanoylamino)phenyl ether of the primary hydroxy group of 3-(propan-2-ylamino)propane-1,2-diol.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"The main purpose of our study was to analyse efficacy and safety of acebutolol (Sectral) in the treatment of hypertension in pregnancy."9.10[Acebutolol in the treatment of arterial hypertension in pregnancy--comparison with commonly used hypertensive agents]. ( Kriska, M; Letkovicová, M; Mlyncek, M; Sirotiaková, J, 2002)
"Twenty pregnant women with mild to moderate hypertension were treated with either methyldopa or acebutolol, a beta-adrenergic blocking agent with cardioselectivity and intrinsic sympathomimetic activity, in a prospective open study."7.66A comparison of acebutolol with methyldopa in hypertensive pregnancy. ( Morrissey, JR; Williams, ER, 1983)
"02; 2--A more frequent adjustment of daily dosage with MD (n = 15) than with ACE (n = 10) or LAB (n = 7); 3--The absence of any significant difference for uricemia level, platelet counts, foetal cardiac rythm, and occurrence of pre-eclampsia (MD = 4; ACE = 3; LAB = 4; 4--An equivalent birth-weight (MD = 3110 +/- 628 g; ACE = 3115 +/- 645."6.66[Randomized, comparative study on the treatment of moderate arterial hypertension during pregnancy: methyldopa, acebutolol, labetalol]. ( Blazquez, G; Gérard, J; Lardoux, H; Leperlier, E, 1988)
"Acebutolol is a cardioselective beta-adrenoceptor blocking drug possessing both partial agonist (intrinsic sympathomimetic) and membrane stabilising activity."6.37Acebutolol. A review of its pharmacological properties and therapeutic efficacy in hypertension, angina pectoris and arrhythmia. ( Singh, BN; Thoden, WR; Ward, A, 1985)
"The main purpose of our study was to analyse efficacy and safety of acebutolol (Sectral) in the treatment of hypertension in pregnancy."5.10[Acebutolol in the treatment of arterial hypertension in pregnancy--comparison with commonly used hypertensive agents]. ( Kriska, M; Letkovicová, M; Mlyncek, M; Sirotiaková, J, 2002)
"A 29-year-old primigravida, diagnosed with ARVD 1 year prior to pregnancy, underwent a full-term, uncomplicated pregnancy and delivery while maintained on acebutolol and an implanted cardioverter defibrillator."3.73Arrhythmogenic right ventricular dysplasia in pregnancy: a case report. ( Bathgate, SL; Lee, LC; Macri, CJ, 2006)
"A prospective study of the hemodynamic and renal changes was undertaken in 11 neonates whose mothers were treated with acebutolol for hypertension during pregnancy, compared with a control group of 11 infants born to normotensive mothers."3.68[Hemodynamic and renal adaptation of newborn infants of hypertensive mothers treated with acebutolol]. ( Boutroy, MJ; Monin, P; Vert, P; Yassen, H, 1992)
"Twenty pregnant women with mild to moderate hypertension were treated with either methyldopa or acebutolol, a beta-adrenergic blocking agent with cardioselectivity and intrinsic sympathomimetic activity, in a prospective open study."3.66A comparison of acebutolol with methyldopa in hypertensive pregnancy. ( Morrissey, JR; Williams, ER, 1983)
"Systolic blood pressure, heart rate, and blood glucose concentration were measured in the first three days of life in 10 infants born to mothers who had received acebutolol, a cardioselective beta-adrenergic-blocking agent, for hypertension in pregnancy and compared with values in 10 infants whose mothers had received methyldopa."3.66Neonatal effects of maternal administration of acebutolol. ( Amiel-Tison, C; Dumez, Y; Hornych, H; Tchobroutsky, C, 1981)
"02; 2--A more frequent adjustment of daily dosage with MD (n = 15) than with ACE (n = 10) or LAB (n = 7); 3--The absence of any significant difference for uricemia level, platelet counts, foetal cardiac rythm, and occurrence of pre-eclampsia (MD = 4; ACE = 3; LAB = 4; 4--An equivalent birth-weight (MD = 3110 +/- 628 g; ACE = 3115 +/- 645."2.66[Randomized, comparative study on the treatment of moderate arterial hypertension during pregnancy: methyldopa, acebutolol, labetalol]. ( Blazquez, G; Gérard, J; Lardoux, H; Leperlier, E, 1988)
"Acebutolol is a cardioselective beta-adrenoceptor blocking drug possessing both partial agonist (intrinsic sympathomimetic) and membrane stabilising activity."2.37Acebutolol. A review of its pharmacological properties and therapeutic efficacy in hypertension, angina pectoris and arrhythmia. ( Singh, BN; Thoden, WR; Ward, A, 1985)
" Evaluation of the iatrogenic risk shows that pharmacologically active amounts of acebutolol might be received by a neonate if the daily maternal dosage exceeds 400 mg/day and/or renal function in the mother is impaired."1.27To nurse when receiving acebutolol: is it dangerous for the neonate? ( Bianchetti, G; Boutroy, MJ; Dubruc, C; Morselli, PL; Vert, P, 1986)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199013 (72.22)18.7374
1990's2 (11.11)18.2507
2000's2 (11.11)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abati, S1
Villa, A1
Cetin, I1
Dessole, S1
Lugliè, PF1
Strohmenger, L1
Ottolenghi, L1
Campus, GG1
Lee, LC1
Bathgate, SL1
Macri, CJ1
Moses, JW1
Borer, JS1
Dubois, D2
Petitcolas, J2
Temperville, B1
Klepper, A1
Catherine, P1
Acritopoulou-Fourcroy, S1
Clabaut, M1
Schrub, JC1
Williams, ER1
Morrissey, JR1
Dumez, Y1
Tchobroutsky, C1
Hornych, H1
Amiel-Tison, C1
Boutroy, MJ3
Vert, P3
Bianchetti, G2
Dubrucq, C1
Morselli, PL2
Crichton, F1
Sirotiaková, J1
Mlyncek, M1
Kriska, M1
Letkovicová, M1
Bouvenot, G1
Escande, M1
Jouve, R1
Delboy, C1
Yassen, H1
Monin, P1
Riant, P1
Urien, S1
Albengres, E1
Duche, JC1
Tillement, JP1
Lardoux, H1
Blazquez, G1
Leperlier, E1
Gérard, J1
Prach, AT1
Rubin, PC1
Dubruc, C1
Singh, BN1
Thoden, WR1
Ward, A1

Reviews

2 reviews available for acebutolol and Pregnancy

ArticleYear
Beta-adrenergic antagonists in the treatment of patients with heart disease.
    Disease-a-month : DM, 1981, Volume: 27, Issue:9

    Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Ca

1981
Acebutolol. A review of its pharmacological properties and therapeutic efficacy in hypertension, angina pectoris and arrhythmia.
    Drugs, 1985, Volume: 29, Issue:6

    Topics: Acebutolol; Angina Pectoris; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Vessels; B

1985

Trials

2 trials available for acebutolol and Pregnancy

ArticleYear
[Acebutolol in the treatment of arterial hypertension in pregnancy--comparison with commonly used hypertensive agents].
    Ceska gynekologie, 2002, Volume: 67, Issue:1

    Topics: Acebutolol; Adolescent; Adult; Antihypertensive Agents; Female; Humans; Hypertension; Pregnancy; Pre

2002
[Randomized, comparative study on the treatment of moderate arterial hypertension during pregnancy: methyldopa, acebutolol, labetalol].
    Archives des maladies du coeur et des vaisseaux, 1988, Volume: 81 Spec No

    Topics: Acebutolol; Adult; Female; Heart Rate, Fetal; Humans; Hypertension; Hypoglycemia; Infant, Newborn; L

1988

Other Studies

14 other studies available for acebutolol and Pregnancy

ArticleYear
Lack of association between maternal periodontal status and adverse pregnancy outcomes: a multicentric epidemiologic study.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2013, Volume: 26, Issue:4

    Topics: Acebutolol; Adolescent; Adult; Case-Control Studies; Female; Fetal Membranes, Premature Rupture; Hum

2013
Arrhythmogenic right ventricular dysplasia in pregnancy: a case report.
    The Journal of reproductive medicine, 2006, Volume: 51, Issue:9

    Topics: Acebutolol; Adult; Anti-Arrhythmia Agents; Arrhythmogenic Right Ventricular Dysplasia; Combined Moda

2006
Treatment of hypertension in pregnancy with beta-adrenoceptor antagonists.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:Suppl 2

    Topics: Abnormalities, Drug-Induced; Acebutolol; Adrenergic beta-Antagonists; Adult; Apgar Score; Atenolol;

1982
Myometrial responses in situ to nicergoline, acebutolol, phentolamine and noradrenaline of the rat in proestrus.
    European journal of pharmacology, 1984, Dec-15, Volume: 107, Issue:1

    Topics: Acebutolol; Animals; Ergolines; Female; Infusions, Parenteral; Injections, Intravenous; Myometrium;

1984
A comparison of acebutolol with methyldopa in hypertensive pregnancy.
    Pharmatherapeutica, 1983, Volume: 3, Issue:7

    Topics: Acebutolol; Adult; Apgar Score; Birth Weight; Blood Pressure; Female; Humans; Hypertension; Infant,

1983
Neonatal effects of maternal administration of acebutolol.
    British medical journal (Clinical research ed.), 1981, Oct-24, Volume: 283, Issue:6299

    Topics: Acebutolol; Blood Glucose; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Infant, Newborn

1981
Infants born to hypertensive mothers treated by acebutolol. Pharmacological studies in the perinatal period.
    Developmental pharmacology and therapeutics, 1982, Volume: 4 Suppl

    Topics: Acebutolol; Adult; Blood Pressure; Female; Hemodynamics; Humans; Hypertension; Infant, Newborn; Kine

1982
Beta blockers in pregnancy and their effect on regional Doppler ultrasound and fetal weight.
    Clinical and experimental obstetrics & gynecology, 1996, Volume: 23, Issue:1

    Topics: Acebutolol; Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Body Weight; Female; Fet

1996
[Beta blockaders and general pathology].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1977, Mar-09, Volume: 53, Issue:10

    Topics: Acebutolol; Adrenergic beta-Antagonists; Asthma; Female; Humans; Hypercalcemia; Hyperglycemia; Hypog

1977
[beta-blockers and high risk pregnancies. Viewpoint of the nephrologist and the obstetrician].
    La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31

    Topics: Acebutolol; Adrenergic beta-Antagonists; Female; Humans; Hypertension; Pindolol; Pregnancy; Pregnanc

1978
[Hemodynamic and renal adaptation of newborn infants of hypertensive mothers treated with acebutolol].
    Archives francaises de pediatrie, 1992, Volume: 49, Issue:4

    Topics: Acebutolol; Diuresis; Female; Hemodynamics; Humans; Hypertension; Infant, Newborn; Kidney; Pregnancy

1992
High plasma protein binding as a parameter in the selection of betablockers for lactating women.
    Biochemical pharmacology, 1986, Dec-15, Volume: 35, Issue:24

    Topics: Acebutolol; Adrenergic beta-Antagonists; Blood Proteins; Female; Humans; Hypertension; Lactation; Mi

1986
Foetoplacental drug clearance in the rabbit: studies with trimazosin, acebutolol and tolmesoxide.
    Xenobiotica; the fate of foreign compounds in biological systems, 1988, Volume: 18, Issue:8

    Topics: Acebutolol; Animals; Arteries; Female; Piperazines; Placenta; Pregnancy; Rabbits; Sulfoxides; Veins

1988
To nurse when receiving acebutolol: is it dangerous for the neonate?
    European journal of clinical pharmacology, 1986, Volume: 30, Issue:6

    Topics: Acebutolol; Breast Feeding; Female; Humans; Hypertension; Infant, Newborn; Milk, Human; Postpartum P

1986