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acebutolol and Muscle Contraction

acebutolol has been researched along with Muscle Contraction in 2 studies

Acebutolol: A cardioselective beta-1 adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm, as well as weak inherent sympathomimetic action.
acebutolol : An ether that is the 2-acetyl-4-(butanoylamino)phenyl ether of the primary hydroxy group of 3-(propan-2-ylamino)propane-1,2-diol.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"Like acebutolol, diacetolol was a more effective isoprenaline antagonist in the heart than in the trachea, thus showing relative cardioselectivity."1.27In vitro studies on the pharmacological properties of diacetolol, the major metabolite of acebutolol in man. ( Borchard, U; Hafner, D; Hirth, C, 1985)
"Pretreatment with acebutolol or propranolol at high concentrations had an inhibitory effect on the contractile response to 5-hydroxytryptamine (5-HT) in most vascular smooth muscles such as rabbit aorta and basilar, mesenteric, renal, femoral arteries and cat coronary artery."1.27The inhibitory actions of acebutolol and propranolol on the contractile response to 5-hydroxytryptamine in various isolated vascular smooth muscles. ( Satake, N; Shibata, S; Ueda, S, 1985)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borchard, U1
Hafner, D1
Hirth, C1
Shibata, S1
Ueda, S1
Satake, N1

Other Studies

2 other studies available for acebutolol and Muscle Contraction

ArticleYear
In vitro studies on the pharmacological properties of diacetolol, the major metabolite of acebutolol in man.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 273, Issue:1

    Topics: Acebutolol; Action Potentials; Adrenergic beta-Antagonists; Animals; Guinea Pigs; Heart Atria; In Vi

1985
The inhibitory actions of acebutolol and propranolol on the contractile response to 5-hydroxytryptamine in various isolated vascular smooth muscles.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1985, Volume: 82, Issue:1

    Topics: Acebutolol; Adrenergic beta-Antagonists; Animals; Arteries; Cats; Male; Muscle Contraction; Muscle,

1985