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acebutolol and Lupus Erythematosus, Systemic

acebutolol has been researched along with Lupus Erythematosus, Systemic in 6 studies

Acebutolol: A cardioselective beta-1 adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm, as well as weak inherent sympathomimetic action.
acebutolol : An ether that is the 2-acetyl-4-(butanoylamino)phenyl ether of the primary hydroxy group of 3-(propan-2-ylamino)propane-1,2-diol.

Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Research Excerpts

ExcerptRelevanceReference
"Acebutolol is a beta blocking agent that induces in C57Bl/6 mice a polyclonal activation of lymphocytes (PAL)."1.28The beta-blocker acebutolol down modulates the spontaneous polyclonal activation of lymphocytes in NZB X NZW lupus mice. ( Alary, C; Appolinaire-Pilipenko, S; f1noist, H; Fournié, GJ; In, S; Lulé, J; Oksman, F; Rollet, C, 1991)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Record, NB1
Simon, P1
Aubert, F1
Boivin, M1
Bonn, F1
Mery, JP1
Stevens, MB1
In, S1
Lulé, J1
f1noist, H1
Oksman, F1
Appolinaire-Pilipenko, S1
Alary, C1
Rollet, C1
Fournié, GJ1
Querin, S1
Feuillet-Fieux, MN1
Jacob, L1
Niel, G1
Bach, JF1
Hourdebaigt-Larrusse, P1
Ziza, JM1
Grivaux, M1

Other Studies

6 other studies available for acebutolol and Lupus Erythematosus, Systemic

ArticleYear
Acebutolol-induced pleuropulmonary lupus syndrome.
    Annals of internal medicine, 1981, Volume: 95, Issue:3

    Topics: Acebutolol; Antibodies; Antibodies, Antinuclear; DNA; Humans; Lupus Erythematosus, Systemic; Male; M

1981
[Lupus syndrom induced by a beta-blocker].
    La Nouvelle presse medicale, 1981, Jan-17, Volume: 10, Issue:2

    Topics: Acebutolol; Adult; Female; Humans; Lupus Erythematosus, Systemic

1981
Drug-induced lupus.
    Hospital practice (Office ed.), 1992, Mar-30, Volume: 27, Issue:3A

    Topics: Acebutolol; Adult; Aged; Antibodies, Antinuclear; Blood Sedimentation; Female; Humans; Lupus Erythem

1992
The beta-blocker acebutolol down modulates the spontaneous polyclonal activation of lymphocytes in NZB X NZW lupus mice.
    International journal of immunopharmacology, 1991, Volume: 13, Issue:5

    Topics: Acebutolol; Age Factors; Albuminuria; Animals; Antibodies, Antinuclear; Cells, Cultured; Down-Regula

1991
Specificity of acebutolol-induced antinuclear antibodies.
    Journal of immunopharmacology, 1986, Volume: 8, Issue:4

    Topics: Acebutolol; Antibodies, Antinuclear; Antibody Specificity; DNA; DNA, Single-Stranded; Histones; Huma

1986
[A new case of lupus induced by acebutolol].
    Annales de cardiologie et d'angeiologie, 1985, Volume: 34, Issue:6

    Topics: Acebutolol; Aged; Antibodies, Antinuclear; Humans; Lupus Erythematosus, Systemic; Male

1985