acebutolol has been researched along with Coronary Disease in 43 studies
Acebutolol: A cardioselective beta-1 adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm, as well as weak inherent sympathomimetic action.
acebutolol : An ether that is the 2-acetyl-4-(butanoylamino)phenyl ether of the primary hydroxy group of 3-(propan-2-ylamino)propane-1,2-diol.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Plasma atrial natriuretic peptide (ANP) was measured during dynamic exercise in 10 patients with coronary heart disease before and after single dose atenolol 50 mg and acebutolol 200 mg, respectively." | 9.06 | Atrial natriuretic peptide during exercise in patients with coronary heart disease before and after single dose atenolol and acebutolol. ( Keller, N; Larsen, J; Storm, T; Sykulski, R; Thamsborg, G, 1988) |
| "In 20 patients with coronary heart disease and typical changes in the exercise ECG (evidence of myocardial hypoxia), which disappeared completely on second ergometry after isosorbid dinitrate, the effect of a single dose of 400 mg acebutolol (Prent) was tested on exercise." | 9.05 | [Acebutolol in coronary heart disease: an ergometric double-blind study (author's transl)]. ( Böhm, H; Ludwig, B, 1980) |
| "In 78 patients with mild or moderate hypertension, effect of acebutolol and hydrochlorothiazide on plasma lipids, lipoproteins, fibrinogen and plasma fibrinolysis time were investigated." | 7.68 | [Does chronic therapy of hypertension with acebutolol or hydrochlorothiazide effect coronary risk factors?]. ( Karolko, B; Kopel, E; Kübler, G; Witkowska, M, 1991) |
| "The effect of the beta-blocking drug acebutolol on the severity of cardiac arrhythmias and the incidence of exercise-induced arrhythmias was studied in 15 patients with chronic coronary artery disease using ambulatory Holter monitoring and bicycle ergometry." | 7.66 | The effect of acebutolol on cardiac arrhythmias in patients with chronic coronary artery disease. ( Burckhardt, D; Raeder, EA, 1980) |
| "Plasma atrial natriuretic peptide (ANP) was measured during dynamic exercise in 10 patients with coronary heart disease before and after single dose atenolol 50 mg and acebutolol 200 mg, respectively." | 5.06 | Atrial natriuretic peptide during exercise in patients with coronary heart disease before and after single dose atenolol and acebutolol. ( Keller, N; Larsen, J; Storm, T; Sykulski, R; Thamsborg, G, 1988) |
| "In 20 patients with coronary heart disease and typical changes in the exercise ECG (evidence of myocardial hypoxia), which disappeared completely on second ergometry after isosorbid dinitrate, the effect of a single dose of 400 mg acebutolol (Prent) was tested on exercise." | 5.05 | [Acebutolol in coronary heart disease: an ergometric double-blind study (author's transl)]. ( Böhm, H; Ludwig, B, 1980) |
| "We assessed the effects of acebutolol, a cardioselective beta blocker, on global and regional left ventricular function in 26 patients with chronic angina pectoris." | 5.05 | Acebutolol and left ventricular function: assessment by radionuclide angiography. ( Bates, HR; Bortz, R; DiBianco, R; Fletcher, RD; Katz, RJ; Laddu, AR; Sauerbrunn, B; Singh, S, 1981) |
| "In 78 patients with mild or moderate hypertension, effect of acebutolol and hydrochlorothiazide on plasma lipids, lipoproteins, fibrinogen and plasma fibrinolysis time were investigated." | 3.68 | [Does chronic therapy of hypertension with acebutolol or hydrochlorothiazide effect coronary risk factors?]. ( Karolko, B; Kopel, E; Kübler, G; Witkowska, M, 1991) |
| "The effect of the beta-blocking drug acebutolol on the severity of cardiac arrhythmias and the incidence of exercise-induced arrhythmias was studied in 15 patients with chronic coronary artery disease using ambulatory Holter monitoring and bicycle ergometry." | 3.66 | The effect of acebutolol on cardiac arrhythmias in patients with chronic coronary artery disease. ( Burckhardt, D; Raeder, EA, 1980) |
| "Acebutolol is a safe and efficacious drug for the prevention of arrhythmias following coronary surgery." | 2.66 | Prevention by acebutolol of rhythm disorders following coronary bypass surgery. ( Collignon, P; Kulbertus, H; Larbuisson, R; Limet, R; Materne, P, 1985) |
| "Acebutolol is a new investigational beta-antagonist which has intrinsic sympathomimetic and cardioselective properties." | 2.65 | Comparative effects of oral acebutolol and propranolol at rest and during exercise in ischemic heart disease: double-blind placebo crossover study utilizing radionuclide ventriculography. ( Hecht, HS; Hopkins, J; Kaul, S; Seidman, R; Singh, BN, 1984) |
| " The dose-response relationship and duration of action of 3'-acetyl-4'-(2-hydroxy-3-isopropylaminopropyl)-butyranilide (acebutolol, Prent) were determined under double-blind conditions in 9 volunteers using heart rate at rest and during exercise as a test parameter." | 2.65 | [Dose-response relationship and duration of action of acebutolol / investigations on heart rate behaviour and ischemic ST-segment depression]. ( Kaltenbach, M; Kober, G; Mikludy, R; Veidt, J, 1982) |
| "The hemodynamic dose-response effects of intravenous acebutolol, a cardioselective beta-adrenoceptor antagonist with intrinsic sympathomimetic activity, were evaluated in 12 male subjects with angiographically confirmed coronary artery disease." | 1.27 | Dose-response effects of cardioselective beta blockade in coronary artery disease. ( Hussain, M; Nelson, G; Silke, B; Taylor, SH; Verma, SP, 1984) |
| "The treatment with acebutolol was effective inducing an improvement of subjective symptoms (reduction of stenocardiac crises, intensity and duration of angor, trinitrin pearls consumption) and an increase of effort tolerance." | 1.26 | [Effects of the administration of acebutolol in patients with chronic angina of effort]. ( Baroni, F; Donegani, E; Forni, B; Uslenghi, E; Zardini, P, 1981) |
| "Pretreatment with acebutolol, 15 min before starting reperfusion, markedly reduced the arrhythmias." | 1.26 | Cardiovascular effects of acebutolol following coronary artery occlusion and reperfusion in anaesthetized dog. ( Chernecki, W; Das, PK; Dhalla, NS; Sharma, GP, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (95.35) | 18.7374 |
| 1990's | 2 (4.65) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burckhardt, D | 1 |
| Raeder, EA | 1 |
| Moses, JW | 1 |
| Borer, JS | 1 |
| Henderson, A | 1 |
| Sheridan, D | 1 |
| Ross, J | 1 |
| Lewis, M | 1 |
| Rosselot, E | 1 |
| Nagai, S | 1 |
| Miyazaki, Y | 1 |
| Ogawa, K | 1 |
| Satake, T | 1 |
| Sugiyama, S | 1 |
| Ozawa, T | 1 |
| Kaul, S | 1 |
| Hecht, HS | 1 |
| Seidman, R | 1 |
| Hopkins, J | 1 |
| Singh, BN | 2 |
| Furuya, Y | 1 |
| Yokoyama, S | 1 |
| Morimoto, S | 1 |
| Nomura, M | 1 |
| Nomura, Y | 1 |
| Fujita, M | 1 |
| Vey, G | 1 |
| Wiese, KH | 1 |
| Schramm, A | 1 |
| Walter, J | 1 |
| Silke, B | 1 |
| Nelson, G | 1 |
| Hussain, M | 1 |
| Verma, SP | 1 |
| Taylor, SH | 1 |
| de Soyza, N | 1 |
| Kane, JJ | 1 |
| Murphy, ML | 1 |
| Laddu, AR | 2 |
| Doherty, JE | 1 |
| Bissett, JK | 1 |
| Strasser, R | 1 |
| Klepzig, H | 1 |
| Hall, RJ | 1 |
| Doran, J | 1 |
| Pusey, C | 1 |
| McHaffie, D | 1 |
| Gibson, DG | 1 |
| Goch, JH | 1 |
| Adamska-Dyniewska, H | 1 |
| Pruszczyński, J | 1 |
| Trela, R | 1 |
| Kober, G | 1 |
| Mikludy, R | 1 |
| Veidt, J | 1 |
| Kaltenbach, M | 1 |
| Hillis, WS | 1 |
| Hutton, I | 1 |
| Lawrie, TD | 1 |
| Pfisterer, M | 1 |
| Müller-Brand, J | 1 |
| Burkart, F | 1 |
| Dalal, JJ | 1 |
| Ross, PJ | 1 |
| Wong, K | 1 |
| Sheridan, DJ | 1 |
| Ruttley, MS | 1 |
| Lewis, MJ | 1 |
| Henderson, AH | 1 |
| Uslenghi, E | 1 |
| Donegani, E | 1 |
| Forni, B | 1 |
| Baroni, F | 1 |
| Zardini, P | 1 |
| Böhm, H | 1 |
| Ludwig, B | 1 |
| Katz, RJ | 2 |
| DiBianco, R | 3 |
| Singh, S | 1 |
| Bortz, R | 1 |
| Bates, HR | 1 |
| Sauerbrunn, B | 1 |
| Fletcher, RD | 2 |
| Yorulmaz, FM | 1 |
| Kuralay, E | 1 |
| Tatar, H | 1 |
| Süer, H | 1 |
| Oztürk, OY | 1 |
| Biron, P | 2 |
| Tremblay, G | 2 |
| Tannenbaum, H | 1 |
| Hugues, FC | 1 |
| Julien, D | 1 |
| Marche, J | 1 |
| Mason, JW | 1 |
| Winkle, RA | 1 |
| Meffin, PJ | 1 |
| Harrison, DC | 2 |
| Schroeder, JS | 1 |
| Chernecki, W | 1 |
| Das, PK | 1 |
| Dhalla, NS | 1 |
| Sharma, GP | 1 |
| Witkowska, M | 1 |
| Kübler, G | 1 |
| Kopel, E | 1 |
| Karolko, B | 1 |
| Puddu, PE | 1 |
| Jouve, R | 1 |
| Langlet, F | 1 |
| Guillen, JC | 1 |
| Fornaris, M | 1 |
| Torresani, J | 1 |
| Reale, A | 1 |
| Bauer, R | 1 |
| Busch, U | 1 |
| Lutilsky, L | 1 |
| van de Flierdt, E | 1 |
| Langhammer, HR | 1 |
| Pabst, HW | 1 |
| Williams, R | 1 |
| Svendsen, TL | 1 |
| Trap-Jensen, J | 1 |
| Carlsen, JE | 1 |
| McNair, A | 1 |
| Singh, SN | 1 |
| Costello, RB | 1 |
| Mason, DT | 1 |
| Chan, MC | 1 |
| Lee, G | 1 |
| Lavanchy, N | 2 |
| Martin, J | 2 |
| Rossi, A | 2 |
| Visioli, O | 1 |
| Bolognesi, R | 1 |
| Cucchini, F | 1 |
| Ferrari, R | 1 |
| Keller, N | 1 |
| Sykulski, R | 1 |
| Thamsborg, G | 1 |
| Storm, T | 1 |
| Larsen, J | 1 |
| Yabe, Y | 1 |
| Morishita, T | 1 |
| Stankusheva, G | 1 |
| Draganov, V | 1 |
| Manolov, P | 1 |
| Giacomelli, M | 1 |
| Materne, P | 1 |
| Larbuisson, R | 1 |
| Collignon, P | 1 |
| Limet, R | 1 |
| Kulbertus, H | 1 |
3 reviews available for acebutolol and Coronary Disease
| Article | Year |
|---|---|
Beta-adrenergic antagonists in the treatment of patients with heart disease.
Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Ca | 1981 |
[Long-term utilization of beta-blockers in arterial hypertension].
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Blood Pressure; Coronary Disease; Drug Toleranc | 1978 |
Antihypertensive therapy and the concept of total cardiovascular protection.
Topics: Acebutolol; Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; | 1987 |
18 trials available for acebutolol and Coronary Disease
| Article | Year |
|---|---|
Comparative effects of oral acebutolol and propranolol at rest and during exercise in ischemic heart disease: double-blind placebo crossover study utilizing radionuclide ventriculography.
Topics: Acebutolol; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Blind Me | 1984 |
[Comparative study of the effect of the calcium antagonist nifedipine, the beta receptor blockers acebutolol and propranolol and their combination on electrophysiologic parameters in the human].
Topics: Acebutolol; Cardiac Catheterization; Coronary Disease; Drug Therapy, Combination; Electrocardiograph | 1984 |
[Dose-response relationship and duration of action of acebutolol / investigations on heart rate behaviour and ischemic ST-segment depression].
Topics: Acebutolol; Adult; Coronary Disease; Dose-Response Relationship, Drug; Electrocardiography; Heart Ra | 1982 |
Combined acebutolol/nifedipine therapy in patients with chronic coronary artery disease: additional improvement of ischemia-induced left ventricular dysfunction.
Topics: Acebutolol; Adult; Aged; Blood Pressure; Coronary Disease; Drug Therapy, Combination; Exercise Test; | 1982 |
[Acebutolol in coronary heart disease: an ergometric double-blind study (author's transl)].
Topics: Acebutolol; Coronary Disease; Double-Blind Method; Exercise Test; Humans; Male; Middle Aged; Physica | 1980 |
Acebutolol and left ventricular function: assessment by radionuclide angiography.
Topics: Acebutolol; Angina Pectoris; Blood Pressure; Coronary Disease; Coronary Vessels; Exercise Test; Hear | 1981 |
Beneficial effects of beta-adrenergic blockade in coronary artery surgery: clinical research.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Cardiotonic Agents; Coronary A | 1993 |
Acebultolol: basis for the prediction of effect on exercise tolerance.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Angina Pectoris; Blood Pressure; Coronary Disease; E | 1976 |
Electrophysiological effects of acebutolol.
Topics: Acebutolol; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Electrocardiogr | 1978 |
Newer antiarrhythmic agents for patients with coronary artery disease.
Topics: Acebutolol; Adult; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; | 1978 |
Differential antianginal responsiveness to acebutolol.
Topics: Acebutolol; Adult; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Dose | 1975 |
Beta-blocking potency and electrophysiologic effects of acebutolol.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aged; Atrioventricular Node; Blood Pressure; Coronar | 1985 |
Effect of acebutolol on left ventricular performance.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aged; Cineangiography; Coronary Disease; Echocardiog | 1985 |
Role of cardioselectivity and intrinsic sympathomimetic activity in beta-blocking drugs in chronic coronary artery disease.
Topics: Acebutolol; Adrenergic beta-Antagonists; Chronic Disease; Clinical Trials as Topic; Coronary Disease | 1987 |
Antihypertensive therapy and the concept of total cardiovascular protection.
Topics: Acebutolol; Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; | 1987 |
The effects of intravenous nifedipine on cardiac hemodynamics and contractility in patients with coronary artery disease in the presence or absence of beta adrenergic blockade.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Blood Pressure; Coronary Circulation; Coronary Disea | 1987 |
Atrial natriuretic peptide during exercise in patients with coronary heart disease before and after single dose atenolol and acebutolol.
Topics: Acebutolol; Aged; Atenolol; Atrial Natriuretic Factor; Clinical Trials as Topic; Coronary Disease; E | 1988 |
Prevention by acebutolol of rhythm disorders following coronary bypass surgery.
Topics: Acebutolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Artery Bypass; Coronary Disease | 1985 |
23 other studies available for acebutolol and Coronary Disease
| Article | Year |
|---|---|
The effect of acebutolol on cardiac arrhythmias in patients with chronic coronary artery disease.
Topics: Acebutolol; Adrenergic beta-Antagonists; Aged; Arrhythmias, Cardiac; Coronary Disease; Electrocardio | 1980 |
Factors relating to the beta blocker withdrawal syndrome.
Topics: Acebutolol; Adrenergic beta-Antagonists; Atenolol; Coronary Disease; Heart Rate; Humans; Hyperthyroi | 1981 |
[Use of beta blockaders in arrhythmias and ischemic heart disease].
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Catechol | 1982 |
The effects of beta-blocking agents on mitochondrial function in ischemic myocardium.
Topics: Acebutolol; Acyl Coenzyme A; Adrenergic beta-Antagonists; Animals; Coronary Disease; Dogs; Female; I | 1984 |
[Effects of acebutolol on the normal and ischemic heart].
Topics: Acebutolol; Animals; Coronary Circulation; Coronary Disease; Dogs; Heart; Oxygen Consumption | 1984 |
Dose-response effects of cardioselective beta blockade in coronary artery disease.
Topics: Acebutolol; Adult; Blood Pressure; Coronary Disease; Dose-Response Relationship, Drug; Heart Rate; H | 1984 |
The long-term suppression of ventricular arrhythmia by oral acebutolol in patients with coronary artery disease.
Topics: Acebutolol; Administration, Oral; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Heart Rate | 1980 |
[Cardiac ischemia on exercise. Effect of nifedipine and acebutolol singly and in combination (author's transl)].
Topics: Acebutolol; Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Double-Blind Method; Dru | 1981 |
The effect of nitroglycerin, beta-blockade with acebutolol and isometric stress on incoordinate left ventricular function.
Topics: Acebutolol; Coronary Disease; Echocardiography; Heart Ventricles; Humans; Isometric Contraction; Kin | 1982 |
[Acebutolol in the treatment of coronary disease - ergometric and polycardiographic studies and evaluation of liver metabolism].
Topics: Acebutolol; Adult; Aged; Biotransformation; Coronary Disease; Heart Function Tests; Humans; Liver; M | 1983 |
The effects of propranolol and acebutolol on left ventricular function and coronary haemodynamics in the conscious dog with myocardial ischaemia.
Topics: Acebutolol; Animals; Coronary Circulation; Coronary Disease; Dogs; Heart; Hemodynamics; Myocardial C | 1980 |
Acute effects of acebutolol on cardiovascular function in man.
Topics: Acebutolol; Adult; Aged; Blood Pressure; Cardiac Output; Coronary Disease; Female; Heart Rate; Hemod | 1981 |
[Effects of the administration of acebutolol in patients with chronic angina of effort].
Topics: Acebutolol; Adult; Angina Pectoris; Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Age | 1981 |
[Effects of beta blockaders on ventilatory function in chronic bronchitis].
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Atenolol; Bronchitis; Chronic Disease; Coronary Dise | 1979 |
Cardiovascular effects of acebutolol following coronary artery occlusion and reperfusion in anaesthetized dog.
Topics: Acebutolol; Anesthesia; Animals; Arrhythmias, Cardiac; Coronary Disease; Dogs; Electrocardiography; | 1978 |
[Does chronic therapy of hypertension with acebutolol or hydrochlorothiazide effect coronary risk factors?].
Topics: Acebutolol; Adult; Coronary Disease; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male | 1991 |
Prevention of postischaemic ventricular fibrillation by long term beta adrenoceptor blockade with acebutolol in the anaesthetised dog.
Topics: Acebutolol; Administration, Oral; Animals; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Coron | 1986 |
The efficacy of nifedipine and acebutolol in coronary artery disease assessed by radionuclide ventriculography.
Topics: Acebutolol; Adult; Blood Pressure; Coronary Disease; Drug Combinations; Exercise Test; Heart Rate; H | 1989 |
Immediate central hemodynamic effects of five different beta-adrenoceptor-blocking agents, acebutolol, atenolol, pindolol, practolol, and propranolol, in patients with ischemic heart disease.
Topics: Acebutolol; Adrenergic beta-Antagonists; Aged; Atenolol; Cardiac Output; Coronary Disease; Heart Rat | 1985 |
Comparative study of the effects of acebutolol, atenolol, d-propranolol and dl,-propranolol on the alterations in energy metabolism caused by ischemia and reperfusion: a 31P NMR study on the isolated rat heart.
Topics: Acebutolol; Adrenergic beta-Antagonists; Animals; Atenolol; Coronary Disease; Energy Metabolism; In | 1988 |
Systemic and coronary hemodynamic effects of beta-adrenoceptor blocking agents in coronary artery disease.
Topics: Acebutolol; Adult; Aged; Blood Pressure; Coronary Circulation; Coronary Disease; Diastole; Female; H | 1987 |
[Hemodynamic changes during treatment with isodinit, sectral, stenopril and kratemon].
Topics: Acebutolol; Adult; Aged; Cardiovascular Agents; Coronary Disease; Delayed-Action Preparations; Drug | 1987 |
Evaluation by 31P NMR of the effects of acebutolol on the ischaemic isolated rat heart.
Topics: Acebutolol; Animals; Coronary Disease; Energy Metabolism; Female; Heart; Hydrogen-Ion Concentration; | 1986 |