Page last updated: 2024-10-21

acebutolol and Asthma

acebutolol has been researched along with Asthma in 9 studies

Acebutolol: A cardioselective beta-1 adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm, as well as weak inherent sympathomimetic action.
acebutolol : An ether that is the 2-acetyl-4-(butanoylamino)phenyl ether of the primary hydroxy group of 3-(propan-2-ylamino)propane-1,2-diol.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"A double-blind, placebo-controlled study of the haemodynamic and ventilatory effects of two beta 1-selective adrenoceptor blockers and their interaction with the beta 2-adrenoceptor agonist terbutaline was carried out in eight asthmatic patients."9.05Ventilatory and haemodynamic effects of terbutaline infusion during beta 1-selective blockade with metoprolol and acebutolol in asthmatic patients. ( Greefhorst, AP; van Herwaarden, CL, 1982)
" Ltd) (300 mg) and acebutolol (Sectral, May & Baker Ltd) (300 mg) were compared in a placebo-controlled, crossover study in ten asthmatics."9.04Comparison of the effects of acebutolol (Sectral) and practolol (Eraldin) on airways obstruction in asthmatics. ( Palmer, KN; Skinner, C, 1975)
"A double-blind, placebo-controlled study of the haemodynamic and ventilatory effects of two beta 1-selective adrenoceptor blockers and their interaction with the beta 2-adrenoceptor agonist terbutaline was carried out in eight asthmatic patients."5.05Ventilatory and haemodynamic effects of terbutaline infusion during beta 1-selective blockade with metoprolol and acebutolol in asthmatic patients. ( Greefhorst, AP; van Herwaarden, CL, 1982)
" Ltd) (300 mg) and acebutolol (Sectral, May & Baker Ltd) (300 mg) were compared in a placebo-controlled, crossover study in ten asthmatics."5.04Comparison of the effects of acebutolol (Sectral) and practolol (Eraldin) on airways obstruction in asthmatics. ( Palmer, KN; Skinner, C, 1975)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19907 (77.78)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greefhorst, AP2
van Herwaarden, CL2
Nakashima, M1
Kawai, M1
Kurasawa, T1
Maekawa, N1
Kino, T1
Mitsuyasu, K1
Oshima, S1
Salpeter, S2
Ormiston, T2
Salpeter, E2
Bouvenot, G1
Escande, M1
Jouve, R1
Delboy, C1
Skinner, C1
Palmer, KN1
Orlando, JP1
Orehek, J1
Eymery, A1
Giacomini, JC1
Thoden, WR1

Reviews

2 reviews available for acebutolol and Asthma

ArticleYear
Cardioselective beta-blocker use in patients with reversible airway disease.
    The Cochrane database of systematic reviews, 2001, Issue:2

    Topics: Acebutolol; Adrenergic beta-Antagonists; Asthma; Celiprolol; Female; Forced Expiratory Volume; Human

2001
Cardioselective beta-blockers for reversible airway disease.
    The Cochrane database of systematic reviews, 2002, Issue:1

    Topics: Acebutolol; Adrenergic beta-Antagonists; Asthma; Celiprolol; Female; Forced Expiratory Volume; Human

2002

Trials

3 trials available for acebutolol and Asthma

ArticleYear
Comparative study of the ventilatory effects of three beta 1-selective blocking agents in asthmatic patients.
    European journal of clinical pharmacology, 1981, Volume: 20, Issue:6

    Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Asthma; Atenolol; Bronchi; Clinical Trials as Topic;

1981
Ventilatory and haemodynamic effects of terbutaline infusion during beta 1-selective blockade with metoprolol and acebutolol in asthmatic patients.
    European journal of clinical pharmacology, 1982, Volume: 23, Issue:3

    Topics: Acebutolol; Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Forced Expiratory

1982
Comparison of the effects of acebutolol (Sectral) and practolol (Eraldin) on airways obstruction in asthmatics.
    British journal of clinical pharmacology, 1975, Volume: 2, Issue:5

    Topics: Acebutolol; Adolescent; Adult; Airway Obstruction; Asthma; Clinical Trials as Topic; Drug Evaluation

1975

Other Studies

4 other studies available for acebutolol and Asthma

ArticleYear
[The effect of acebutolol, beta 1-selective blocker, on patients with essential hypertension and asthma].
    Kokyu to junkan. Respiration & circulation, 1982, Volume: 30, Issue:8

    Topics: Acebutolol; Adult; Aged; Asthma; Female; Humans; Hypertension; Male; Middle Aged

1982
[Beta blockaders and general pathology].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1977, Mar-09, Volume: 53, Issue:10

    Topics: Acebutolol; Adrenergic beta-Antagonists; Asthma; Female; Humans; Hypercalcemia; Hyperglycemia; Hypog

1977
[Study of clinical pharmacology of acebutolol in 5 asthmatic patients].
    La Nouvelle presse medicale, 1975, Dec-31, Volume: 4, Issue:46 Suppl

    Topics: Acebutolol; Aerosols; Asthma; Blood Pressure; Heart Rate; Humans; Isoproterenol; Maximal Expiratory

1975
Ancillary pharmacologic properties of acebutolol: cardioselectivity, partial agonist activity, and membrane-stabilizing activity.
    American heart journal, 1985, Volume: 109, Issue:5 Pt 2

    Topics: Acebutolol; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Asthma; Bronchi; Cell Membrane; H

1985