acadesine has been researched along with Heart Disease, Ischemic in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (92.86) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hardie, DG | 1 |
| Bullough, D; Mullane, K | 1 |
| Burckhartt, B; Cohen, MV; Downey, JM; Mullane, KM; Tsuchida, A; Yang, XM | 2 |
| Alkhulaifi, AM; Pugsley, WB | 1 |
| Barash, P; Curling, P; Hollenberg, M; Leung, JM; Mangano, DT; Mathew, J; Reves, JG; Salmenpera, M; Stanley, T | 1 |
| Fox, KM; Holdright, DR; Sparrow, JL; Steiner, J; Wright, CL | 1 |
| Hori, M; Inoue, M; Kamada, T; Kitakaze, M; Komamura, K; Minamino, T; Morioka, T; Node, K; Sato, H; Takashima, S | 1 |
| Downey, JM; Liu, GS; Mullane, K; Tsuchida, A | 1 |
| de Jong, JW; de Jonge, R; Friedman, J; Macleod, DC; Serruys, PW; Suryapranata, H; van Es, GA | 1 |
| Hill, GE | 1 |
| Bache, RJ; Duncker, DJ; Ishibashi, Y; Klassen, C; Quebbeman, BB | 1 |
| Richardt, G; Schreieck, J | 1 |
| Hori, M; Kitakaze, M; Kuzuya, T; Minamino, T; Mori, H; Node, K; Shinozaki, Y; Takashima, S | 1 |
3 review(s) available for acadesine and Heart Disease, Ischemic
| Article | Year |
|---|---|
AMP-activated protein kinase: the guardian of cardiac energy status.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apoptosis; Energy Metabolism; Enzyme Activation; Humans; Models, Biological; Multienzyme Complexes; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Necrosis; Protein Serine-Threonine Kinases; Ribonucleosides; Trans-Activators | 2004 |
Harnessing an endogenous cardioprotective mechanism: cellular sources and sites of action of adenosine.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Carrier Proteins; Dogs; Endothelium, Vascular; Energy Metabolism; Guinea Pigs; Humans; Myocardial Infarction; Myocardial Ischemia; Myocardium; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Rats; Receptors, Purinergic P1; Reperfusion Injury; Ribonucleosides; Signal Transduction | 1995 |
Cardiopulmonary bypass-induced inflammation: is it important?
Topics: Aminoimidazole Carboxamide; Anti-Inflammatory Agents; Cardiopulmonary Bypass; Cell Adhesion; Child; Cytokines; Down-Regulation; Endothelium, Vascular; Endotoxins; Hemofiltration; Humans; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-1; Interleukin-6; Macrophage-1 Antigen; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Platelet Activation; Ribonucleosides; Serine Proteinase Inhibitors; Systemic Inflammatory Response Syndrome; Tumor Necrosis Factor-alpha; Up-Regulation; Ventricular Dysfunction, Left | 1998 |
3 trial(s) available for acadesine and Heart Disease, Ischemic
| Article | Year |
|---|---|
An initial multicenter, randomized controlled trial on the safety and efficacy of acadesine in patients undergoing coronary artery bypass graft surgery. SPI Research Group.
Topics: Aged; Aminoimidazole Carboxamide; Coronary Artery Bypass; Double-Blind Method; Elective Surgical Procedures; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Ischemia; Ribonucleosides; Safety | 1994 |
Effect of acadesine, a new metabolic agent, on exercise-induced myocardial ischemia in chronic stable angina.
Topics: Aged; Aminoimidazole Carboxamide; Angina Pectoris; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Exercise Test; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Ischemia; Placebos; Ribonucleosides; Time Factors | 1994 |
Effect of acadesine on myocardial ischaemia in patients with coronary artery disease.
Topics: Adult; Aged; Aminoimidazole Carboxamide; Cardiac Catheterization; Coronary Disease; Female; Hemodynamics; Humans; Lactic Acid; Male; Middle Aged; Myocardial Ischemia; Ribonucleosides; Ventricular Function, Left | 1997 |
8 other study(ies) available for acadesine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Acadesine extends the window of protection afforded by ischaemic preconditioning in conscious rabbits.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Disease Models, Animal; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Ribonucleosides; Time Factors; Ventricular Fibrillation | 1995 |
Role of acadesine in clinical myocardial protection.
Topics: Aminoimidazole Carboxamide; Clinical Trials as Topic; Humans; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Ribonucleosides | 1995 |
AICA riboside improves myocardial ischemia in coronary microembolization in dogs.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Aminoimidazole Carboxamide; Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Cytosol; Dogs; Energy Metabolism; Myocardial Ischemia; Myocardium; Oxygen Consumption; Ribonucleosides; Thromboembolism | 1994 |
Acadesine extends the window of protection afforded by ischaemic preconditioning.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Female; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Ribonucleosides; Theophylline; Time Factors | 1994 |
Acadesine lowers temporal threshold for the myocardial infarct size limiting effect of preconditioning.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Female; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Rabbits; Receptors, Purinergic; Ribonucleosides; Time Factors | 1993 |
Acadesine increases blood flow in the collateralized heart during exercise.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Collateral Circulation; Coronary Circulation; Dogs; Female; Heart; Hemodynamics; Infusions, Intravenous; Male; Myocardial Ischemia; Physical Conditioning, Animal; Ribonucleosides | 1998 |
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines | 1999 |
Improvement by 5-amino-4-imidazole carboxamide riboside of the contractile dysfunction that follows brief periods of ischemia through increases in ecto-5-nucleotidase activity and adenosine release in canine hearts.
Topics: 5'-Nucleotidase; Adenosine; Aminoimidazole Carboxamide; Animals; Dogs; Hemodynamics; Myocardial Contraction; Myocardial Ischemia; Myocardium; Purinergic P1 Receptor Antagonists; Reperfusion; Ribonucleosides | 1999 |