acadesine has been researched along with Disease Models, Animal in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Abdullahi, A; Auger, C; Jeschke, MG; Knuth, CM; Parousis, A; Samadi, O | 1 |
| Beà, S; Campàs, C; Colomer, D; de Frias, M; Kalko, SG; López-Guerra, M; Montraveta, A; Pérez-Galán, P; Rosich, L; Roué, G; Salaverria, I; Xargay-Torrent, S | 1 |
| Al-Rewashdy, H; Jasmin, BJ; Lin, W; Ljubicic, V; Renaud, JM | 1 |
| Cambon, K; Déglon, N; Dolores Sequedo, M; Farina, F; Millán, JM; Neri, C; Parker, AJ; Vázquez-Manrique, RP; Weiss, A | 1 |
| Fujinami, K; Kamoshita, M; Ozawa, Y; Toda, E; Tsubota, K | 1 |
| Chakour, KS; Freund, GG; Guest, CB | 1 |
| Belcher, JD; Geng, JG; Huo, Y; Slungaard, A; Tang, R; Viollet, B; Wang, H; Wang, J; Wu, C; Zhang, C; Zhang, W; Zhu, C | 1 |
| Burckhartt, B; Cohen, MV; Downey, JM; Mullane, KM; Tsuchida, A; Yang, XM | 1 |
| Fabian, TC; Kudsk, KA; Proctor, KG; Spiers, JP | 1 |
| Gruver, EJ; Marsh, JD; Smith, TW; Toupin, D | 1 |
| Bullough, DA; Montag, A; Mullane, KM; Young, MA; Zhang, C | 1 |
| Kingma, JG; Rouleau, JR; Simard, D | 1 |
| Davis, KA; Fabian, TC; Proctor, KG; Ragsdale, DN; Trenthem, LL | 1 |
| Proctor, KG; Ragsdale, DN | 1 |
15 other study(ies) available for acadesine and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Metformin prevents the pathological browning of subcutaneous white adipose tissue.
Topics: Acetyl-CoA Carboxylase; Adipocytes, Beige; Adipose Tissue, White; Adult; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Burns; Disease Models, Animal; Humans; Lipolysis; Metformin; Mice; Mice, Inbred C57BL; Mitochondria; Okadaic Acid; Oxidative Phosphorylation; Protein Phosphatase 2; Ribonucleosides; Sterol Esterase; Subcutaneous Fat | 2019 |
Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma.
Topics: Aminoimidazole Carboxamide; Animals; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cohort Studies; Disease Models, Animal; Drug Synergism; Female; Humans; Lymphoma, Mantle-Cell; Mice; Mice, SCID; Random Allocation; Ribonucleosides; Rituximab; Xenograft Model Antitumor Assays | 2014 |
Utrophin A is essential in mediating the functional adaptations of mdx mouse muscle following chronic AMPK activation.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Disease Models, Animal; Dystroglycans; Female; Genotyping Techniques; Hand Strength; Male; Mice; Mice, Inbred mdx; Mice, Knockout; Muscular Dystrophy, Duchenne; Myofibrils; Phenotype; Ribonucleosides; Utrophin | 2015 |
AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease.
Topics: Adenosine Monophosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Brain; Caenorhabditis elegans; Cell Death; Corpus Striatum; Disease Models, Animal; Humans; Huntington Disease; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neostriatum; Neurons; Phosphorylation; Ribonucleosides | 2016 |
Neuroprotective effect of activated 5'-adenosine monophosphate-activated protein kinase on cone system function during retinal inflammation.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cell Line, Tumor; Disease Models, Animal; Glial Fibrillary Acidic Protein; Lipopolysaccharides; Male; Mice, Inbred C57BL; Mitochondria; Neuroprotective Agents; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Random Allocation; Retinal Cone Photoreceptor Cells; Retinitis; Ribonucleosides; RNA, Messenger; Tumor Necrosis Factor-alpha | 2016 |
Macropinocytosis is decreased in diabetic mouse macrophages and is regulated by AMPK.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cell Culture Techniques; Cell Line, Tumor; Diabetes Mellitus, Type 2; Disease Models, Animal; Energy Metabolism; Glucose; Hyperglycemia; Immunity; Leptin; Macrophage Activation; Macrophages, Peritoneal; Mice; Pinocytosis; Pyrazoles; Pyrimidines; Ribonucleosides | 2008 |
Acadesine inhibits tissue factor induction and thrombus formation by activating the phosphoinositide 3-kinase/Akt signaling pathway.
Topics: Adenosine A2 Receptor Antagonists; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apolipoproteins E; Atherosclerosis; Blood Coagulation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Fibrinolytic Agents; Humans; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; NF-kappa B; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyrimidines; Receptor, Adenosine A2A; Ribonucleosides; RNA, Messenger; Sepsis; Signal Transduction; Thromboplastin; Transcription Factor AP-1; Triazines; Triazoles; Up-Regulation; Venous Thrombosis | 2010 |
Acadesine extends the window of protection afforded by ischaemic preconditioning in conscious rabbits.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Disease Models, Animal; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Ribonucleosides; Time Factors; Ventricular Fibrillation | 1995 |
Resuscitation of hemorrhagic shock with hypertonic saline/dextran or lactated Ringer's supplemented with AICA riboside.
Topics: Aminoimidazole Carboxamide; Animals; Buffers; Dextrans; Disease Models, Animal; Female; Hemodynamics; Hypertonic Solutions; Lactates; Male; Oxygen Consumption; Reperfusion Injury; Ribonucleosides; Shock, Hemorrhagic; Sodium Chloride; Swine | 1993 |
Acadesine improves tolerance to ischemic injury in rat cardiac myocytes.
Topics: Aminoimidazole Carboxamide; Animals; Disease Models, Animal; Female; Heart; In Vitro Techniques; Myocardial Contraction; Myocardial Reperfusion Injury; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Ribonucleosides; Theophylline | 1994 |
Adenosine-mediated inhibition of platelet aggregation by acadesine. A novel antithrombotic mechanism in vitro and in vivo.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Aminoimidazole Carboxamide; Animals; Aspirin; Blood Physiological Phenomena; Coronary Thrombosis; Coronary Vessels; Dipyridamole; Disease Models, Animal; Dogs; Erythrocytes; Humans; Male; Plasma; Platelet Aggregation; Purinergic P1 Receptor Antagonists; Regional Blood Flow; Ribonucleosides; Theophylline; Tubercidin | 1994 |
Timely administration of AICA riboside reduces reperfusion injury in rabbits.
Topics: Aminoimidazole Carboxamide; Animals; Autoradiography; Disease Models, Animal; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Rabbits; Ribonucleosides; Tetrazolium Salts | 1994 |
Endogenous adenosine and secondary injury after chest trauma.
Topics: Acidosis; Adenosine; Aminoimidazole Carboxamide; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Evaluation, Preclinical; Hemodynamics; Hypercapnia; Inflammation; Leukocyte Count; Peroxidase; Ribonucleosides; Survival Analysis; Swine; Thoracic Injuries; Wounds, Nonpenetrating | 2000 |
Acadesine and intestinal barrier function after hemorrhagic shock and resuscitation.
Topics: Adenosine; Adenosine Kinase; Aminoimidazole Carboxamide; Animals; Blood Flow Velocity; Capillary Permeability; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Fluid Therapy; Formycins; Ileum; Intestinal Mucosa; Ischemia; Laser-Doppler Flowmetry; Male; Resuscitation; Ribonucleosides; Shock, Hemorrhagic; Swine | 2000 |