acadesine has been researched along with B-Cell Chronic Lymphocytic Leukemia in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Albericio, F; Cosialls, AM; de la Banda, E; Gil, J; González-Barca, EM; González-Gironès, DM; Iglesias-Serret, D; Lavilla, R; Núñez-Vázquez, S; Pomares, H; Pons, G; Preciado, S; Saura-Esteller, J | 1 |
| Drew, BG; Kingwell, BA | 1 |
| Alonso, E; Benito, A; Campàs, C; Coll-Mulet, L; Cosialls, AM; de Frias, M; Gil, J; González-Barca, E; González-Gironès, DM; Iglesias-Serret, D; Labi, V; Pons, G; Santidrián, AF; Villunger, A; Viollet, B | 1 |
| Campàs, C; Cazin, B; de Frias, M; González-Barca, E; Janssens, A; Levy, V; Pérez de Oteyza, J; Saunders, A; Terol, MJ; Van Den Neste, E; Zachee, P | 1 |
| Barragán, M; Bellosillo, B; Campàs, C; Colomer, D; Gil, J; Lopez, JM; Santidrián, AF | 1 |
1 review(s) available for acadesine and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
Acadesine, an adenosine-regulating agent with the potential for widespread indications.
Topics: Adenosine; Aminoimidazole Carboxamide; Coronary Artery Bypass; Diabetes Mellitus; Humans; Infusions, Intravenous; Leukemia, Lymphocytic, Chronic, B-Cell; Myocardial Reperfusion Injury; Ribonucleosides | 2008 |
1 trial(s) available for acadesine and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
Acadesine for patients with relapsed/refractory chronic lymphocytic leukemia (CLL): a multicenter phase I/II study.
Topics: Aged; Aminoimidazole Carboxamide; B-Lymphocytes; Cohort Studies; Drug Resistance, Neoplasm; Female; Humans; Karnofsky Performance Status; Leukemia, Lymphocytic, Chronic, B-Cell; Lymph; Lymphocyte Count; Male; Maximum Tolerated Dose; Middle Aged; Recurrence; Ribonucleosides; T-Lymphocytes | 2013 |
3 other study(ies) available for acadesine and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells through the upregulation of NOXA and synergizes with ibrutinib, 5-aminoimidazole-4-carboxamide riboside or venetoclax.
Topics: Adenine; Aminoimidazole Carboxamide; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Hydrocarbons, Fluorinated; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Piperidines; Prohibitins; Proto-Oncogene Proteins c-bcl-2; Pyrazoles; Pyrimidines; Repressor Proteins; Ribonucleosides; Sulfonamides; Thiazolidines; Tumor Cells, Cultured; Up-Regulation | 2017 |
AICAR induces apoptosis independently of AMPK and p53 through up-regulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells.
Topics: Adult; Aged; Aged, 80 and over; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Line, Tumor; Cells, Cultured; Female; Gene Expression Regulation, Leukemic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Membrane Proteins; Mice; Middle Aged; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Ribonucleosides; Tumor Suppressor Protein p53; Up-Regulation | 2010 |
Acadesine activates AMPK and induces apoptosis in B-cell chronic lymphocytic leukemia cells but not in T lymphocytes.
Topics: Adenosine; Amino Acid Chloromethyl Ketones; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Antimetabolites, Antineoplastic; Apoptosis; B-Lymphocytes; Caspases; Cyclic AMP-Dependent Protein Kinases; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; MAP Kinase Signaling System; Mitochondria; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Neoplasm Proteins; Neoplastic Stem Cells; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Ribonucleosides; Ribonucleotides; T-Lymphocytes; Tubercidin; Tumor Cells, Cultured | 2003 |