abyssomicin-c and HIV-Infections

abyssomicin-c has been researched along with HIV-Infections* in 1 studies

Other Studies

1 other study(ies) available for abyssomicin-c and HIV-Infections

Article	Year
Abyssomicin 2 reactivates latent HIV-1 by a PKC- and HDAC-independent mechanism. Organic letters, 2015, Jan-16, Volume: 17, Issue:2 Screening of a marine natural products library afforded three new analogues of the tetronic acid containing polyketide abyssomicin family and identified abyssomicin 2 as a selective reactivator of latent HIV virus. Examination of the mode of action of this new latent HIV reactivating agent demonstrated that it functions via a distinct mechanism compared to that of existing reactivating agents and is effective at reactivating latent virus in a subset of primary patient cell lines. Topics: Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Furans; Histone Deacetylase Inhibitors; HIV Infections; HIV-1; Humans; Molecular Structure; Polyketides; Protein Kinase C; Virus Latency	2015

Article

Year

Abyssomicin 2 reactivates latent HIV-1 by a PKC- and HDAC-independent mechanism.

Organic letters, 2015, Jan-16, Volume: 17, Issue:2

Screening of a marine natural products library afforded three new analogues of the tetronic acid containing polyketide abyssomicin family and identified abyssomicin 2 as a selective reactivator of latent HIV virus. Examination of the mode of action of this new latent HIV reactivating agent demonstrated that it functions via a distinct mechanism compared to that of existing reactivating agents and is effective at reactivating latent virus in a subset of primary patient cell lines.

Topics: Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Furans; Histone Deacetylase Inhibitors; HIV Infections; HIV-1; Humans; Molecular Structure; Polyketides; Protein Kinase C; Virus Latency

2015