abyssinone-ii has been researched along with Bacterial-Infections* in 1 studies
1 other study(ies) available for abyssinone-ii and Bacterial-Infections
Article | Year |
---|---|
Evaluation of flavonoid and resveratrol chemical libraries reveals abyssinone II as a promising antibacterial lead.
Lead on! In the course of screening flavonoid and resveratrol libraries, abyssinone II, a naturally occurring prenylated flavonoid, was found to exhibit relatively good antitubercular and antibacterial activity. Preliminary mechanistic studies revealed that abyssinone II hyperpolarizes the bacterial membrane potential and inhibits the biosynthesis of key cellular macromolecules (DNA, RNA, and protein). Topics: Anti-Bacterial Agents; Antitubercular Agents; Bacteria; Bacterial Infections; Flavonoids; Humans; Mycobacterium tuberculosis; Resveratrol; Small Molecule Libraries; Stilbenes | 2012 |