abiraterone has been researched along with Prostatic Neoplasms, Castration-Resistant in 514 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 333 (64.79) | 24.3611 |
2020's | 181 (35.21) | 2.80 |
Authors | Studies |
---|---|
Cao, C; Chen, Y; Li, X; Yan, G; Yu, J; Zhang, L; Zhou, F; Zhou, P | 1 |
Endo, S; Fujii, S; Fujimoto, N; Gouda, H; Hu, D; Iguchi, K; Ikari, A; Irie, K; Kawai, M; Matsukawa, T; Matsunaga, T; Nakayama, T; Oguri, H; Okada, T; Segawa, J; Toyooka, N; Xia, S | 1 |
Endo, S; Fujimoto, N; Fujita, M; Ikari, A; Ikeda, H; Ishikawa, T; Kamatari, YO; Kudo, Y; Matsunaga, T; Okada, T; Ota, A; Tanaka, Y; Toyooka, N | 1 |
Lu, Z; Luo, X; Meng, X; Wang, A; Wang, Y; Yang, Y | 1 |
Kulkarni, AA; Lutsey, PL; Prizment, A; Rao, A; Rubin, N; Ryan, CJ; Shah, S; Tholkes, A | 1 |
Alverbratt, C; Fallara, G; Garmo, H; Hjelm Eriksson, M; Lissbrant, IF; Stattin, P; Vikman, H | 1 |
Ai, J; Bai, S; Lei, H; Liao, D; Peng, G; Qiu, S; Wei, Q; Xiong, X; Xu, H; Yang, L; Yi, X | 1 |
Benedi-González, J; Bilbao Gomez-Martino, C; Díaz Almirón, M; Escario-Gómez, M; Espinosa Arranz, E; García Trevijano Cabetas, M; González-Del Valle, L; Herrero Ambrosio, A; Romero-Garrido, JA; Sobrino Jiménez, C | 1 |
Andrikopoulou, A; Briasoulis, A; Dimopoulos, MA; Fiste, O; Gavriatopoulou, M; Gumeni, S; Kaparelou, M; Kastritis, E; Koutsoukos, K; Kunadis, E; Liontos, M; Markellos, C; Skafida, E; Terpos, E; Trougakos, IP; Zagouri, F | 1 |
Azad, AA; Bonnitcha, P; Briscoe, K; Butler, LM; Crumbaker, M; Davis, ID; Du, P; Fettke, H; Fitzpatrick, M; Horvath, LG; Huynh, K; Jia, S; Joshua, AM; Kwan, EM; Lin, HM; Mahon, KL; Mak, B; Marx, G; Meikle, PJ; Meikle, TG; Mellett, NA; Scheinberg, T; Stockler, MR; Stricker, PD; Sullivan, DR; Tran, B; Yeung, N; Yu, J; Zhang, A | 1 |
Freedland, SJ; George, DJ; Huang, A; Janjan, N; Mardekian, J; Ramaswamy, K; Russell, D; Schultz, NM | 1 |
Ito, T; Koie, T; Miyake, H; Naiki, T; Nakane, K; Shiroki, R; Sugiyama, Y; Takahara, K; Yasui, T | 1 |
Blanchet, P; Brureau, L; Gourtaud, G; Roux, V; Sadreux, Y; Senechal, C; Vestris, PG | 1 |
Geynisman, DM; Heiss, BL; Martinez, E; Stadler, WM; Szmulewitz, RZ; Wong, ASC; Yong, WP | 1 |
Long, Q; Mamtani, R; Marar, M; Narayan, V; Parikh, RB; Vapiwala, N | 1 |
Beamud-Cortés, M; Collado-Borrell, R; Escudero-Vilaplana, V; García-Sánchez, S; Herranz, A; Narrillos-Moraza, Á; Pérez-Ramírez, S; Sanjurjo, M; Vicente-Valor, J; Villanueva-Bueno, C | 1 |
Agarwal, N; Azad, A; Benzaghou, F; Carles, J; Chowdhury, S; Kerloeguen, Y; Kimura, A; McGregor, B; Merseburger, AS; Mohamed, N; Oudard, S; Pal, S; Panneerselvam, A; Saad, F; Soares, A; Wang, F | 1 |
Arlt, W; de Ridder, CMA; Graeser, R; Hofland, J; Jenster, GW; Moll, JM; Taylor, AE; Teubel, WJ; van Weerden, WM | 1 |
Collado-Borrell, R; Escudero-Vilaplana, V; Herranz, A; López-López, C; Revuelta-Herrero, JL; Ruiz-Briones, P; Sanjurjo, M; Somoza-Fernández, B; Vicente-Valor, J; Villanueva-Bueno, C | 1 |
Cattarino, S; Gentilucci, A; Mariotti, G; Salsiccia, S; Sciarra, A | 1 |
Chiba, S; Egawa, S; Habuchi, T; Hata, K; Hatakeyama, S; Horikawa, Y; Ishida, T; Kashima, S; Kimura, T; Koizumi, A; Kumazawa, T; Maita, S; Narita, S; Nomura, K; Ohyama, C; Okane, K; Sato, H; Shimoda, J; Suzuki, T; Takayama, K; Yamamoto, R; Yanagisawa, T | 1 |
Bryce, AH; Gao, H; Gu, Y; Kalari, KR; Kim, W; Qin, B; Qin, S; Scholz, JA; Sinnwell, JP; Tan, W; Wang, L; Wei, L; Weinshilboum, RM; Xie, F; Yin, P; Yu, J; Zhang, H; Zhuang, Y | 1 |
Caram, MEV; Hollenbeck, BK; Kaufman, SR; Lai, LY; Oerline, MK; Shahinian, VB; Tsao, PA | 1 |
Cintra, MTG; Costa, AL; de Almeida, DCB; de Carvalho, FB; de Oliveira Faria, BL | 1 |
Calais, G; Cancel, M; Florence, AM; Fromont, G; Laurent, E; Linassier, C; Narciso, B; Pobel, C | 1 |
Bian, C; Chen, X; Gao, Y; He, D; Hou, Z; Huang, S; Li, Z; Liu, Y; Mei, Z; Qin, Y; Tan, Q; Wang, C; Wang, X; Wu, D; Xu, C; Yang, T; Zhang, X; Zhu, X; Zhuang, Q | 1 |
Fujimoto, N; Fukuda, A; Harada, K; Hiroshige, T; Igawa, T; Minato, A; Mizushima, Y; Nagata, Y; Obara, W; Tomisaki, I | 1 |
Anderson, M; Cao, Y; Chang, M; Rojas, V; Trieu, J; Varada, N; Vogelzang, NJ | 1 |
Anand, A; Bian, C; Chen, S; Chi, Y; Huang, S; Li, Z; Liu, Y; Qin, Y; Richter, J; Tian, J; Wang, C; Wang, W; Wu, D; Xu, C; Yang, T; Zhang, L; Zhu, X | 1 |
Aggarwal, RR; Borno, HT; Bucknor, M; Kwon, DH; Paciorek, A; Small, EJ; Zhang, L | 1 |
Allegra, A; Aquilano, M; Cerbai, C; Ciccone, LP; Desideri, I; Detti, B; Di Cataldo, V; Francolini, G; Garlatti, P; Guerrieri, B; Livi, L; Loi, M; Lucidi, S; Mangoni, M; Meattini, I; Salvestrini, V; Stocchi, G; Visani, L | 1 |
Beránek, J; Danielak, D; Krejčí, T | 1 |
Kelly, WK; Lu-Yao, G; Shah, YB; Shaver, AL | 1 |
Alekseev, B; Burgents, J; Chiuri, VE; Clarke, NW; Degboe, A; Fléchon, A; Gresty, C; Jassem, J; Jones, R; Kang, J; Kocak, I; Redfern, C; Saad, F; Sala, N; Thiery-Vuillemin, A; Wiechno, P | 1 |
Chang, YH; Chu, YC; Chuang, CK; Hsieh, ML; Huang, LK; Kan, HC; Lee, CL; Lin, PH; Liu, CY; Pang, ST; Shao, IH; Wu, CT; Yu, KJ | 1 |
Bennett, CL; Carson, KR; Drake, BF; Eisen, SA; Knoche, EM; Luo, S; Reimers, MA; Sanfilippo, KM; Schoen, MW; Whitmer, AL; Yan, Y | 1 |
Bhargava, V; Bryce, AH; Carlson, RE; Dehm, SM; Gormley, M; Hillman, DW; Jimenez, RE; Kalari, KR; Kohli, M; Li, Y; Qin, S; Sicotte, H; Sinnwell, JP; Tan, W; Vedell, PT; Wang, L; Weinshilboum, RM | 1 |
Armstrong, A; Jiang, XS; Labriola, MK; Seale, KN | 1 |
Ellis, CS; Kolesar, JM; McCorkle, JR; Myint, ZW; Otto, DE; Wang, P; Wu, J | 1 |
Chang, CF; Chang, KC; Chang, PH; Chang, YH; Chen, HK; Chen, HY; Chuang, CK; Hsieh, CH; Huang, WK; Kuan, FC; Kuo, YC; Lai, EC; Lin, PH; Lin, YC; Pang, ST; Sheng, TW; Su, PJ; Su, YL; Tsan, DL; Wang, YL; Yu, KJ; Yu, SM | 1 |
Borsellino, N; Fazio, I; Galanti, D; La Vecchia, M; Lo Casto, A | 1 |
Eto, M; Habuchi, T; Huang, M; Kagaya, H; Kashima, S; Miura, M; Nara, T; Narita, S; Numakura, K; Saito, M; Shiota, M; Takahashi, Y; Yamamoto, R | 1 |
Balk, SP; Chen, S; Croucher, PJP; Dalrymple, S; Einstein, DJ; Erlander, MG; Isaacs, JT; Jonas, O; Luo, J; Makusha, L; Nouri, M; Patterson, JC; Rashed, S; Ridinger, M; Varkaris, A; Varmeh, S; Whitman, MA; Xie, F; Yaffe, MB | 1 |
Egawa, S; Eto, M; Haginaka, J; Horiyama, S; Inoue, R; Kanji, H; Kobayashi, K; Matsuyama, H; Shiota, M; Tashiro, K | 1 |
Habuchi, T; Hamaya, T; Hashimoto, Y; Hata, K; Hatakeyama, S; Kimura, T; Narita, S; Ohyama, C; Okamoto, T; Ozaki, K; Tanaka, T; Togashi, K; Yamamoto, H; Yanagisawa, T; Yoneyama, T | 1 |
Cao, H; Chen, L; Feng, Y; Gao, R; Song, Z; Wang, D | 1 |
Cetin, B; Gumusay, O; Wabl, CA | 1 |
Enei, Y; Fukuokaya, W; Habuchi, T; Hara, S; Hata, K; Hatakeyama, S; Kimura, T; Matsukawa, A; Miki, J; Miyajima, K; Mori, K; Nakazono, M; Narita, S; Ohyama, C; Otsuka, T; Sano, T; Shariat, SF; Yanagisawa, T; Yata, Y | 1 |
Bracarda, S; Chen, G; Chi, KN; de Bono, J; Garcia, J; Harris, A; Hinton, H; Massard, C; Matsubara, N; Olmos, D; Sandhu, S; Sane, R; Schenkel, F; Sternberg, CN; Sweeney, C | 1 |
Deng, WM; Gao, X; He, YD; Li, LY; Luo, ZH; Meng, ZA; Tang, XM; Tao, W; Wang, BY; Xia, TL; Zhang, LX | 1 |
Chen, T; Ding, J; Gu, T; Li, J; Zhu, Q | 1 |
Abida, W; Bambury, RM; Bryce, AH; Chowdhury, S; Daugaard, G; Despain, D; Emmenegger, U; Fizazi, K; Gingerich, JR; Heidenreich, A; Heyes, CA; Krieger, L; Lindberg, H; Loehr, A; McDermott, R; Morris, D; Nolè, F; Ostler, P; Pintus, E; Piulats, JM; Reaume, MN; Redfern, C; Ryan, CJ; Sáez, MI; Sautois, B; Sridhar, SS; Staffurth, J; Watkins, SP | 1 |
Deris, A; Sohrabi-Haghighat, M | 1 |
Beuzeboc, P; Sabouret, A | 1 |
Antonarakis, ES; Armstrong, AJ; Danila, DC; George, DJ; Gore, Y; Gupta, S; Halabi, S; Nanus, DM; Roy, A; Szmulewitz, RZ; Tubbs, A; Wenstrup, R; Yang, Q | 1 |
Cai, D; Chen, J; Chen, N; Chen, Y; Dai, J; Hu, X; Liang, J; Liu, H; Liu, Z; Ni, Y; Nie, L; Pan, X; Shen, P; Sun, G; Wang, M; Wang, Z; Xu, N; Yin, W; Yin, X; Zeng, H; Zeng, Y; Zhang, X; Zhang, Y; Zhao, F; Zhao, J; Zheng, L; Zhu, S; Zhu, X | 1 |
Cunha André, M; Gameiro Marques, R; Leal Carvalho, M; Mendonça Macedo, A; Silva Figueira, N | 1 |
Abida, W; Antonarakis, ES | 1 |
Annala, M; Benoist, GE; Boerrigter, E; Donnellan, G; Hamberg, P; Herberts, C; Kwan, EM; Mehra, N; Ng, SWS; Schalken, JA; Somford, DM; Sumiyoshi, T; Tolmeijer, SH; van Erp, NP; van Oort, IM; Wyatt, AW | 1 |
Antonarakis, ES; Armstrong, AJ; Beltran, H; Beumer, JH; Bobek, O; Bryce, AH; Goldkorn, A; Hahn, O; Halabi, S; Heller, G; Hillman, DW; Langevin, B; Lewis, LD; McGary, EC; Mehan, PT; Morris, MJ; Roth, BJ; Ryan, C; Schwartz, L; Small, EJ; Taplin, ME; Watt, C; Xiao, H | 1 |
Danyi, A; de Jong, AC; de Ridder, J; de Wit, R; Feng, F; Lolkema, MP; Sjöström, M; van Riet, J | 1 |
Barata, PC; Caputo, SA; Casado, CV; Gupta, K; Habibian, N; Hawkins, ME; Huang, M; Jaeger, EB; Jang, A; Lanka, SM; Layton, JL; Ledet, EM; Lewis, BE; Lieberman, AD; Miller, PJ; Pocha, O; Sartor, O; Schwartz, J; Sweeney, PL | 1 |
Gong, N; Huang, S; Wang, X; Xiang, Z; Xu, C; Yi, C; You, X; Yu, J | 1 |
Balusson, F; Gravis, G; Kerbrat, S; Mathieu, R; Oger, E; Scailteux, LM; Vincendeau, S | 1 |
Abdel-Gawad, O; Atawia, IM; Gupta, S; Kushwaha, PP; Lin, S; Shankar, E; Verma, S | 1 |
Deol, ES; Fiala, MA; Luo, S; Mian, H; Sanfilippo, KM; Schoen, MW; Wildes, T | 1 |
Sartor, O | 2 |
Buck, SAJ; de Bruijn, P; de Wit, R; Ghobadi-Moghaddam-Helmantel, IM; Koolen, SLW; Lam, MH; Mathijssen, RHJ | 1 |
Bloor, LE; Bohnert, ASB; Burns, J; Caram, MEV; Entenman, S; Kumbier, K; Skolarus, TA; Sparks, JB; Tsao, PA | 1 |
Antonarakis, ES; Arafa, AT; Blader, LR; Engle, J; Jha, G; Ramakrishna, K; Ryan, CJ; Zorko, NA | 1 |
Cho, JS; Choi, SM; Choi, WS; Choi, YD; Chung, BH; Hong, SH; Jeon, SS; Jeong, SH; Kang, TW; Kim, BH; Kim, SY; Kwak, C; Kwon, D; Kwon, TG; Lee, HJ; Lee, NR; Park, SW; Shin, SJ; Yeon, SE; Yun, SJ | 1 |
Al-Rejaie, SS; Baker, A; Elgorban, AM; Mohany, M; Sajid Khan, M; Syed, A | 1 |
Bergman, AM; Buck, SAJ; Coenen, MJH; de Jonge, E; de Wit, R; Huitema, ADR; Koolen, SLW; Mathijssen, RHJ; Meertens, M; Oomen-de Hoop, E; van Ooijen, FMF; van Schaik, RHN | 1 |
O'Reilly, D | 1 |
Boegemann, M; Kessel, K; Rahbar, K; Schäfers, M; Schlack, K; Seifert, R; Weckesser, M | 1 |
Arasaratnam, M; Bhatnagar, A; Crumbaker, M; Gurney, H; McKay, MJ; Molloy, MP; Thaysen-Andersen, M | 1 |
Bisbjerg, R; Fode, M; Kistorp, CM; Kvorning Ternov, K; Lindberg, H; Palapattu, G; Sønksen, J; Østergren, PB | 1 |
Bamias, A; Carles, J; Castellano, D; de Bono, J; de Wit, R; Eymard, JC; Feyerabend, S; Fizazi, K; Geffriaud-Ricouard, C; Helissey, C; Iacovelli, R; Kramer, G; Melichar, B; Ozatilgan, A; Sternberg, CN; Sverrisdóttir, Á; Theodore, C; Tombal, B; Wülfing, C | 1 |
Artigas, C; Flamen, P; Gil, T; Martinez Chanza, N; Peltier, A; Plouznikoff, N; Sideris, S | 1 |
Aghaee-Bakhtiari, SH; Jalili, A; Mahjoubin Tehran, M; Rezaei, S; Sahebkar, A | 1 |
Anceschi, U; Brassetti, A; Calabrò, F; Cindolo, L; De Nunzio, C; Ferriero, M; Flammia, RS; Gallucci, M; Ghahhari, J; Giacinti, S; Guaglianone, S; Leonardo, C; Mastroianni, R; Schips, L; Simone, G; Tema, G; Tubaro, A; Tuderti, G | 1 |
Allioli, N; Crouzet, S; Decaussin-Petrucci, M; Freyer, G; Gillet, PG; Maillet, D; Peron, J; Plesa, A; Rimokh, R; Ruffion, A; Tartas, S; Vlaeminck-Guillem, V | 1 |
Ai, J; Dong, X; Han, X; Peng, R; Wei, Q; Xu, H; Yang, L; Zhao, X; Zheng, X | 1 |
Hadaschik, B; Hess, J; Hess-Busch, Y | 1 |
Karaağaç, M; Karakurt Eryılmaz, M | 1 |
Corona, SP; D'Angelo, A; Roviello, G; Sobhani, N | 1 |
Balestra, A; Droz-Perroteau, C; Fizazi, K; Fourrier-Reglat, A; Guiard, E; Joly, F; Jove, J; Lacueille, C; Lamarque, S; Moore, N; Oudard, S; Rouyer, M; Tubach, F | 1 |
Condon, B; Liskaser, G; Murphy, DG; Thangasamy, IA | 1 |
Aschelter, AM; De Sanctis, V; Macrini, S; Marchetti, P; Marinelli, L; Osti, MF; Reverberi, C; Tronnolone, L; Valeriani, M | 1 |
Ploussard, G | 1 |
Appleman, LJ; Chatta, K; DiPippo, VA; Fleming, MT; Gore, I; Hussain, A; Israel, RJ; McClay, EF; Mega, AE; Modiano, M; Olson, WC; Petrylak, DP; Sartor, AO; Shore, ND; Singh, P; Smith, DC; Somer, B; Stambler, N; Tagawa, ST; Vogelzang, NJ; Wadlow, R | 1 |
Azuma, H; Fujiwara, Y; Hirano, H; Ibuki, N; Ichihashi, A; Inamoto, T; Komura, K; Matsunaga, T; Minami, K; Nishimoto, Y; Nomi, H; Saito, K; Takahara, K; Takai, T; Tanaka, T; Tanda, N; Taniguchi, K; Tsujino, T; Tsutsumi, T; Uchimoto, T; Uehara, H; Yoshikawa, Y | 1 |
Barata, PC; Chapman, L; Christensen, BR; Cotogno, P; Layton, JL; Ledet, EM; Lewis, BE; Manogue, C; Moses, M; Ranasinghe, L; Sartor, O; Steinwald, P | 1 |
Gotoh, M; Hattori, K; Hattori, R; Ishikawa, T; Kato, M; Kawanishi, H; Naito, Y; Sano, T; Tochigi, K; Tsuzuki, T; Yamamoto, A; Yuba, T | 1 |
Badrising, SK; Beeker, A; Bergman, AM; Celik, F; Coenen, JLLM; Haanen, JB; Hamberg, P; Lam, MGEH; Loosveld, OJL; Louhanepessy, RD; Oostdijk, A; van der Noort, V; Vegt, E; Wagenaar, N; Zuetenhorst, H; Zwart, W | 1 |
Higa, J; Larsen, C; Savino, S; Scholz, M; Vogelzang, N; Wilenius, K | 1 |
Assenholt, J; Hansen, TF; Madsen, JS; Osther, PJS; Zedan, AH | 1 |
Ahmed, ME; Andrews, JR; Bryce, AH; Karnes, RJ; Kwon, E | 1 |
Banna, GL; Basso, U; Benanti, C; Bimbatti, D; De Giorgi, U; Di Quattro, R; Libra, M; Lipari, H; Malatino, L; Pitrè, A; Rundo, F; Schepisi, G; Urzia, V | 1 |
Casadei, C; Cursano, MC; De Giorgi, U; Iuliani, M; Paganelli, G; Santini, D; Stellato, M; Tonini, G | 1 |
Feng, Y; Guan, Y; Liao, G; Pang, J; Tong, T; Xiong, H | 1 |
Arenas-Bonilla, AJ; Flores-Martín, JF; Galisteo-Moya, R; Gutiérrez-Tejero, F; Moreno-Jiménez, J; Nieblas-Toscano, D; Ramos-Alaminos, CI; Salas-Moreno, MC; Velarde-Muñoz, C | 1 |
George, DJ; Higano, CS; Jiao, X; Kalinovský, J; Miller, K; Saad, F; Sartor, O; Sternberg, CN; Tangirala, K; Tombal, B | 1 |
Baser, O; George, DJ; Huang, A; Lechpammer, S; Mardekian, J; Ramaswamy, K; Sandin, R; Schultz, NM; Wang, L | 1 |
Deng, T; Ge, R; Lin, X; Long, X; Olumi, AF; Taplin, ME; Wang, H; Wang, Z; Wu, CL; Wu, S; Zhang, Z | 1 |
Briganti, A; Egawa, S; Karakiewicz, PI; Kimura, S; Kimura, T; Miura, N; Mori, K; Mostafaei, H; Pradere, B; Quhal, F; Sari Motlagh, R; Shariat, SF | 1 |
Hu, S; Liu, C; Song, S; Su, H; Wang, B; Xu, X; Ye, D; Zhang, Y; Zhu, Y | 1 |
Carretero-González, A; Castellano, D; de Velasco, G; Lora, D; Lorente, D; Manneh, R | 1 |
De Bono, J; Gibbs, P; IJzerman, M; Kwan, EM; Pereira-Salgado, A; Tran, B | 1 |
Chen, C; Fang, H; Ge, H; He, H; He, L; Wan, Y; Wang, L; Wang, Y; Wu, Y | 1 |
Csizmarik, A; Fazekas, T; Grünwald, V; Hadaschik, B; Hüttl, A; Jurányi, Z; Kocsis, Z; Kramer, G; Maj-Hes, A; Nyirády, P; Püllen, L; Sevcenco, S; Shariat, SF; Szarvas, T | 1 |
Alvarez-Madrazo, S; Baillie, K; Bennie, M; Cameron, D; Clarke, J; Crearie, C; Jones, RJ; Kavanagh, K; Keel, A; Kurdi, A; Laskey, J; Morrison, D; Mueller, T; Pan, J; Wu, O | 1 |
Adelman, CA; Agarwal, N; Burgents, J; Chi, KN; de Bono, J; Fizazi, K; Goessl, C; Hussain, M; Kang, J; Kohlmann, A; Mateo, J; Mehra, N; Olmos, D; Saad, F; Sandhu, S; Sartor, O; Shore, N; Thiery-Vuillemin, A; Twardowski, P; Wu, W | 1 |
Csizmarik, A; Keresztes, D; Küronya, Z; Nagy, N; Nyirády, P; Riesz, P; Szarvas, T; Váradi, M | 1 |
Antonarakis, ES; Bertan, C; Carreira, S; Chen, Y; De Bono, JS; Dolling, D; Fountain, J; Isaacs, WB; Lu, C; Luo, J; Sharp, A; Terbuch, A; Wang, H; Yu, J | 1 |
George, DJ; Higano, CS; Jiao, X; Kalinovsky, J; Miller, K; Saad, F; Sartor, O; Shore, N; Sternberg, CN; Tangirala, K; Tombal, B | 1 |
Abou Chakra, M; Dellis, A; Moussa, M; Papatsoris, A; Sryropoulou, D | 1 |
Egawa, S; Fukuokaya, W; Kimura, S; Kimura, T; Koike, Y; Miki, K; Sasaki, H; Tashiro, K; Tsuzuki, S; Urabe, F | 1 |
Hu, X; Liu, L; Wang, S; Wang, W; Wang, X; Yang, H; Yu, X; Zhang, X | 1 |
Annala, M; Aragón, IM; Castro, E; Cendón, Y; Chi, KN; Finch, DL; Gleave, ME; Khalaf, DJ; Lorente, D; Lozano, R; Oja, C; Olmos, D; Pacheco, MI; Romero-Laorden, N; Taavitsainen, S; Vergidis, J; Wyatt, AW; Zulfiqar, M | 1 |
Sharifi, N | 1 |
Antonarakis, ES; Carducci, MA; Denmeade, SR; Eisenberger, MA; Fu, W; Luo, J; Markowski, MC; Marshall, CH; Ngomba, N; Paller, CJ; Rifkind, I; Schweizer, MT; Sinibaldi, V; Sullivan, R; Teply, BA; Wang, H | 1 |
Allman, K; Barata, P; Fallah, J; Garcia, JA; Gilligan, TD; Gupta, R; Li, H; Martin, A; Ornstein, MC; Rini, BI; Sheng, IY | 1 |
Attard, G; Casadei, C; Conteduca, V; De Giorgi, U; Demichelis, F; Gonzalez-Billalabeitia, E; Gurioli, G; Jayaram, A; Lolli, C; Matteucci, F; Paganelli, G; Romanel, A; Scarpi, E; Schepisi, G; Tandefelt, DG; Wetterskog, D; Wingate, A | 1 |
Aparicio, A; Araujo, JC; Boukovala, M; Corn, PG; Efstathiou, E; Hoang, A; Kim, J; Logothetis, CJ; Pagliaro, L; Spetsieris, N; Subudhi, SK; Tannir, NM; Troncoso, P; Tsikkinis, A; Tu, SM; Wang, J; Wang, X; Weldon, JA; Wen, S; Zurita, AJ | 1 |
Abida, W; Aggarwal, RR; Alumkal, JJ; Attwell, S; Bauman, L; Campeau, E; Feng, FY; Heath, EI; Lakhotia, S; Nanus, DM; Norek, K; Pantuck, AJ; Schweizer, MT; Small, EJ; Snyder, M | 1 |
Agarwal, N; Barata, PC; Cotogno, P; Hahn, AW; Layton, J; Ledet, E; Lewis, B; Lilly, MB; Manogue, C; Moses, M; Niu, A; Nussenzveig, R; Sartor, O | 1 |
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Attard, G; Jayaram, A; Wetterskog, D | 1 |
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Karrison, T; Ratain, MJ; Stadler, WM; Szmulewitz, RZ | 1 |
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Brown, JS; Cunningham, JJ; Gatenby, RA; Staňková, K | 1 |
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Chen, J; Gao, AC; Liao, B; Liu, J; Liu, Z; Shen, P; Shu, K; Sun, G; Yang, Y; Zeng, H; Zhang, X; Zhao, J; Zhao, P | 1 |
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Taneja, SS | 3 |
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Armstrong, CM; Chen, HW; Dall'Era, M; Evans, CP; Gao, AC; Liu, C; Liu, L; Lombard, AP; Lou, W; Noel, ODV; Tepper, CG; Yang, JC; Zhao, R | 1 |
Bryce, AH; Dorff, TB; Groshen, S; Ji, L; Quinn, DI; Wong, W; Yap, KK | 1 |
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Bristow, RG; Gillessen, S; Oing, C; Rebello, RJ | 1 |
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Morgans, AK; Ryan, CJ | 1 |
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Chen, X; Chen, Y; Gong, U; Jiang, A; Li, G; Niu, Y; Shang, Z; Sun, G; Wei, F | 1 |
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Chen, Z; Li, X; Lin, Z; Ma, X; Wu, X; Zou, L | 1 |
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Carraro, P; Dittadi, R; Polesello, V; Zivi, A | 1 |
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Barata, PC; Sartor, AO | 1 |
Anderson, AR; Brown, JS; Dinh, MN; Gatenby, RA; West, JB; Zhang, J | 1 |
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Dubinsky, S; Emmenegger, U; McFarlane, TRJ; McLeod, AG; Thawer, A | 1 |
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Agarwal, N; Bellmunt, J; DiLorenzo, G; Sonpavde, G; Vogelzang, NJ; Zhang, TY | 1 |
Attard, G; Lim, AC | 1 |
Hotte, SJ; Loblaw, DA; Walker-Dilks, C; Winquist, E | 1 |
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de Wit, R; Fitzpatrick, JM | 1 |
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de Morrée, ES; de Wit, R; Mathijssen, RH; Moll, JM; Teubel, W; van Royen, ME; van Soest, RJ; van Weerden, WM; Wiemer, EA | 1 |
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Brändle, M; Fornaro, J; Gillessen, S; Omlin, A; Rothermundt, C; Rupp, NJ; Schmid, S | 1 |
Li, B; Liu, SX; Xia, J; Zhang, TS; Zhou, ZR | 1 |
Chandler, DW; Haqq, CM; Kheoh, T; Molina, A; Peng, W; Ryan, CJ; Scher, HI; Welkowsky, E | 1 |
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Agarwal, N; Antonarakis, ES; Azad, A; Batten, JA; Cheng, HH; Chi, KN; Galsky, MD; Gulati, R; Heath, EI; Leiter, A; Montgomery, RB; Nadal, R; Pal, SK; Rehman, HT; Twardowski, P; Vaishampayan, UN; Yu, EY | 1 |
Dahut, WL; Madan, R | 1 |
Carles, J; de Bono, JS; De Porre, P; de Souza, P; Fizazi, K; Flaig, TW; Griffin, TW; Higano, CS; Kheoh, T; Li, J; Logothetis, CJ; Miller, K; Molina, A; Mulders, PF; Naini, V; Park, YC; Rathkopf, DE; Ryan, CJ; Saad, F; Shore, ND; Small, EJ; Smith, MR; Sternberg, CN; Taplin, ME; Yu, MK | 1 |
Armstrong, AJ; Chin, B; Dhawan, MS; George, DJ; Harrison, MR; Healy, P; Oldan, J; Zhang, T | 1 |
Anderson, SA; Azad, AA; Bazov, J; Bell, RH; Chi, KN; Collins, CC; Gleave, ME; Haegert, A; Le Bihan, S; McConeghy, B; Paris, P; Shukin, R; Small, EJ; Thomas, G; Volik, SV; Wang, Y; Wyatt, AW; Youngren, J | 1 |
Attard, G; Bianchini, D; Crespo, M; de Bono, JS; Ferraldeschi, R; Figueiredo, I; Flohr, P; Lorente, D; Miranda, S; Nowakowska, K; Riisnaes, R; Rodrigues, DN; Sideris, S; Terstappen, LW; van Dalum, G; Zafeiriou, Z | 1 |
Dan, TD; Den, RB; Dicker, AP; Eldredge-Hindy, HB; Gomella, LG; Hoffman-Censits, J; Hurwitz, MD; Kelly, WK; Lallas, CD; Lin, J; Trabulsi, EJ | 1 |
Ndibe, C; Sonpavde, G; Wang, CG | 1 |
Alexandre, J; Belleville, T; Blanchet, B; Goldwasser, F; Huillard, O; Noé, G; Thomas-Schoemann, A; Vidal, M | 1 |
Abajo Del Álamo, C; Catalá Pindado, MÁ; Godoy Díez, M; Moreno Gómez, Á | 1 |
Berlin, A; Fernández, MI | 1 |
Amadori, D; Attard, G; Bianchi, E; Burgio, SL; Calistri, D; Carretta, E; Casadio, V; Conteduca, V; De Giorgi, U; Masini, C; Menna, C; Rossi, L; Salvi, S | 1 |
Berruti, A; Bertaglia, V; Buttigliero, C; Fioramonti, M; Iuliani, M; Pantano, F; Ribelli, G; Santini, D; Scagliotti, GV; Tonini, G; Tucci, M; Vignani, F; Vincenzi, B; Zoccoli, A | 1 |
Vignot, S | 1 |
Caffo, O; Chiuri, VE; Conteduca, V; De Giorgi, U; Derosa, L; Fratino, L; Maines, F; Petracci, E; Santini, D; Santoni, M; Testoni, S; Veccia, A | 1 |
Alyamani, M; Auchus, RJ; Bishop, AC; Bunch, D; Dreicer, R; Garcia, JA; Li, Z; Liu, J; Sharifi, N; Upadhyay, SK | 1 |
Penning, TM | 1 |
Bianco, V; Fiaschi, AI; Francini, E; Laera, L; Petrioli, R; Ponchietti, R; Roviello, G | 1 |
Antonarakis, ES; Maughan, BL | 2 |
Azoitei, A; Cronauer, MV; Damjanoski, I; Jentzmik, F; Zengerling, F | 1 |
Antonarakis, ES; Carducci, MA; Chen, Y; Eisenberger, MA; Lu, C; Luo, J; Nakazawa, M; Paller, CJ | 1 |
Rexer, H | 2 |
Bambury, RM; Rathkopf, DE | 1 |
He, L; Li, L; Long, Z | 1 |
Antonarakis, ES; Carducci, MA; Chen, Y; Denmeade, SR; Eisenberger, MA; Lu, C; Luber, B; Luo, J; Nadal, R; Nakazawa, M; Paller, CJ; Wang, H | 1 |
Crawford, ED; Higano, CS; Hussain, M; Petrylak, DP; Shore, ND | 1 |
Bianco, V; Fiaschi, AI; Francini, E; Francini, F; Laera, L; Petrioli, R; Roviello, G | 1 |
Bhargava, R; Hendricks, AR; Neyra, JA; Rocha, NA; Rodan, AR; Vaidya, OU | 1 |
Benoist, GE; Gerritsen, WR; Kramers, C; Mulders, PF; Schers, HJ; van Erp, PH; Westdorp, H | 1 |
Bergman, AM; Bos, MM; Chitu, D; de Morrée, ES; de Wit, R; Goey, SH; Hamberg, P; Mathijssen, RH; Nieuweboer, AJ; van der Meer, N; van Soest, RJ | 1 |
Albiges, L; Antoun, S; Bayar, A; di Palma, M; Escudier, B; Fizazi, K; Ileana, E; Laplanche, A; Loriot, Y; Massard, C | 1 |
Antonarakis, ES; Bassi, S; Maughan, BL; Nadal, R; Schweizer, MT; Suzman, DL; Xhou, XC | 1 |
Bria, E; Caffo, O; Galligioni, E; Maines, F; Tortora, G; Trentin, C; Veccia, A | 1 |
Bertaglia, V; Bironzo, P; Buttigliero, C; Di Maio, M; Scagliotti, GV; Tucci, M; Vignani, F | 1 |
Assi, R; Mukherji, D; Shamseddine, A; Temraz, S | 1 |
Audenet, F; Basset, V; Branchereau, J; de La Taille, A; Flamand, V; Lebdai, S; Lebret, T; Murez, T; Neuzillet, Y; Ploussard, G | 1 |
Aarts, MJ; Badrising, SK; Bergman, AM; Coenen, JL; de Jong, IJ; Gelderblom, H; Haanen, JB; Hamberg, P; Kerver, ED; Los, M; van den Berg, HP; van den Eertwegh, AJ; van der Noort, V; van Oort, IM; van Voorthuizen, T; Vrijaldenhoven, S; Warmerdam, F | 1 |
Barber, J; Button, MR; Davies, RS; Lester, JF; Palaniappan, N; Smith, C; Staffurth, J; Tanguay, J | 1 |
Alesini, D; Basso, U; Caffo, O; Campadelli, E; Conteduca, V; D'Angelo, A; De Giorgi, U; Donini, M; Ermacora, P; Fratino, L; Gasparro, D; Giordano, M; Lo Re, G; Lolli, C; Maines, F; Massari, F; Messina, C; Procopio, G; Ratta, R; Veccia, A; Verderame, F; Zagonel, V | 1 |
Bunz, T; Chamberlin, KW; Clement, JM; Holle, LM; Niemann, C; Patel, JM | 1 |
Amadori, D; Attard, G; Bianchini, D; Carreira, S; Casadio, V; Casiraghi, N; Conteduca, V; de Bono, JS; De Giorgi, U; Demichelis, F; Ferraldeschi, R; Flohr, P; Gasi Tandefelt, D; Goodall, J; Gurioli, G; Jayaram, A; Rescigno, P; Romanel, A; Salvi, S; Tunariu, N; Wetterskog, D; Wingate, A; Zafeiriou, Z | 1 |
Schweizer, MT; Yu, EY | 1 |
Moore, A; Moore, DC | 1 |
Savage, N | 1 |
Alibhai, SM; Aziz, S; Breunis, H; Joshua, AM; Manokumar, T; Rizvi, SF; Tannock, IF | 1 |
Antonarakis, ES; Denmeade, SR; Luber, B; Teply, BA | 1 |
Bertaglia, V; Buttigliero, C; Di Maio, M; Scagliotti, GV; Tucci, M; Vignani, F | 1 |
Balk, SP; Cai, C; Chen, S; Gao, S; Gerrin, S; Han, W; Mostaghel, EA; Nelson, PS; Patnaik, A; Sharma, A; Sowalsky, AG; Taplin, ME; Voznesensky, O; Wang, H; Ye, H; Yu, Z | 1 |
Burgio, SL; Carretta, E; Casadio, V; Conteduca, V; Costantini, M; De Giorgi, U; Menna, C; Rossi, L; Salvi, S; Zoli, W | 1 |
Brasso, K; Røder, MA; Thim, S; Thortzen, A | 1 |
Boegemann, M; Eminaga, O; Herrmann, E; Hinkelammert, R; Krabbe, LM; Mikah, P; Papavassilis, P; Schrader, AJ; Semjonow, A | 1 |
Gschwend, JE; Hatzichristodoulou, G; Heck, MM; Höppner, M; Kübler, H; Luppa, PB; Maurer, T; Nawroth, R; Retz, M; Schmid, SC; Seitz, AK; Tauber, R; Thaler, MA; Thalgott, M | 1 |
Graham, L; Schweizer, MT | 1 |
Armstrong, C; Gao, AC; Liu, C; Lou, W; Zhu, Y | 1 |
Davies, RS; Lester, JF; Smith, C | 1 |
Barsová, L; Bartoš, J; Chalupa, J; Dvořák, J; Forster, J; Hejzlarová, V; Holikova, M; Richter, I; Sochor, M; Stankuš, I | 1 |
de Bono, JS; Figueiredo, I; Lorente, D; Plymate, SR; Rescigno, P; Riisnaes, R; Rodrigues, DN; Sharp, A; Sun, S; Welti, J; Zafeiriou, Z | 1 |
Divine, GW; Hafron, JM; Hung, J; Hwang, C; Taylor, AR | 1 |
Adamo, V; Barni, S; Boccardo, F; Bruno, M; Caffo, O; Caserta, C; Chiuri, VE; De Giorgi, U; De Vincenzo, F; De Vivo, R; Derosa, L; Dinota, A; Facchini, G; Fratino, L; Grassi, P; Messina, C; Mosca, A; Porcu, L; Procopio, G; Ricotta, R; Santini, D; Scavelli, C; Surace, G; Susi, M; Tartarone, A; Verzoni, E; Zaniboni, A | 1 |
Abazeed, M; Alyamani, M; Auchus, RJ; Balk, SP; Li, J; Li, Z; Rogacki, K; Sharifi, N; Taplin, ME; Upadhyay, SK | 1 |
Antoun, J; Bteich, F; Ghosn, M; Jalkh, A; Kourie, HR | 1 |
Baeten, K; Bianchini, D; Crespo, M; Danila, DC; de Bono, JS; Figueiredo, I; Fleisher, M; Flohr, P; Kheoh, T; Lorente, D; Mateo, J; McCormack, R; Miranda, S; Molina, A; Olmos, D; Scher, HI; Seed, G; Terstappen, LW | 1 |
Caffo, O; Sharifi, N | 1 |
Uemura, H | 1 |
Azuma, H; Inamoto, T | 1 |
Azoitei, A; Cronauer, MV; Godau, B; Hoda, MR; Merseburger, AS; Schmid, E | 1 |
Antonarakis, ES; Eshleman, JR; Frick, KD; Luo, J; Markowski, MC | 1 |
Arslan, C | 1 |
Azad, A; Black, PC; Chi, KN; Eigl, BJ; Gao, J; Gleave, ME; Joshua, AM; Stewart, C; Todenhöfer, T | 1 |
Dhawan, M; Ryan, CJ | 1 |
Bernemann, C; Boegemann, M; Luedeke, M; Schnoeller, TJ; Schrader, AJ; Steinestel, J; Steinestel, K | 1 |
Antonarakis, ES; Luber, B; Maughan, BL; Nadal, R | 1 |
Berger, I; Kramer, G; Madersbacher, S; Mohamad Al-Ali, B | 1 |
Gschwend, J; Miller, K; Wolff, JM | 1 |
Balk, SP; Bhasin, M; Bubley, GJ; Domachevsky, L; Kantoff, PW; Lis, R; Marck, BT; Matsumoto, AM; McKay, RR; Montgomery, B; Mostaghel, EA; Taplin, ME; Voznesensky, O; Werner, L; Zhang, Z; Zukotynski, KA | 1 |
Biasco, E; Crucitta, S; Danesi, R; Del Re, M; Derosa, L; Falcone, A; Galli, L; Jenster, GW; Miccoli, M; Orlandini, C; Rofi, E; van Schaik, RH | 1 |
Balea-Filgueiras, J; Martín-Herranz, I; Ramudo-Cela, L; Vizoso-Hermida, JR | 1 |
Cookson, MS; Ritch, CR | 1 |
Antonarakis, ES; Attard, G | 1 |
Aitoku, Y; Basurto, E; Concialdi, K; DiBonaventura, M; Kimura, G; Ledesma, DA; Matsubara, N; McKinnon, I; Mohamed, AF; Narimatsu, A; Uemura, H; Wang, E; Yamaguchi, A | 1 |
Srinivas, NR | 1 |
De Porre, P; Xu, S | 1 |
Bubley, GJ; Fiorillo, M; Heath, EI; McKay, RR; Montgomery, RB; Roberts, J; Taplin, ME; Werner, L | 1 |
Aroasio, E; Berruti, A; Bertaglia, V; Buttigliero, C; DI Maio, M; Scagliotti, GV; Tucci, M; Vignani, F | 1 |
Albiges, L; Attard, G; Bianchini, D; de Bono, J; Fizazi, K; Loriot, Y; Massard, C; Mateo, J; Mehra, N; Petrylak, DP; Pezaro, C; Ryan, CJ; Shen, L; Varga, A | 1 |
Fenner, A | 1 |
Chopra, A; Georgieva, M; Haaland, B; Lopes, G; Yeo, CM | 1 |
Cristofanilli, M; Hoffman-Censits, JH; Kelly, WK; Kennedy, B; Kilpatrick, D; Leiby, B; Lewis, N; Lin, J; Mu, Z; Patel, SA; Sama, AR; Yang, H; Ye, Z | 1 |
Aringer, M; Boegemann, M; Krabbe, LM; Rahbar, K; Schlack, K; Schrader, AJ; Semjonow, A; Steinestel, J; Thomes, S | 1 |
Appleman, L; Beumer, JH; Holleran, JL; Kim, KP; Lewis, LD; Morris, MJ; Parise, RA; van Erp, N | 1 |
Bezrukov, EA; Kondrashina, AV; Rapoport, LM | 1 |
Concepcion, RS; Crawford, ED; Finkelstein, SE; Gomella, LG; Keane, TE; Koo, PJ; O'Sullivan, JM; Petrylak, DP; Saad, F; Shore, N; Sieber, P; Slovin, SF; Stone, NN; Tombal, B; Vogelzang, NJ; Yu, EY | 1 |
93 review(s) available for abiraterone and Prostatic Neoplasms, Castration-Resistant
Article | Year |
---|---|
Efficacy and safety of bipolar androgen therapy in mCRPC after progression on abiraterone or enzalutamide: A systematic review.
Topics: Androgens; Androstenes; Benzamides; Disease Progression; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Testosterone; Treatment Outcome | 2022 |
Lower Fracture Rates in Patients Treated with Radium-223, Abiraterone or Enzalutamide, When Given Concurrently with Bone Health Agents: A Real-World Analysis.
Topics: Abiraterone Acetate; Aged; Androgen Antagonists; Androgens; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Density; Denosumab; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Radium; Retrospective Studies; Zoledronic Acid | 2022 |
Increasing the efficacy of abiraterone - from pharmacokinetics, through therapeutic drug monitoring to overcoming food effects with innovative pharmaceutical products.
Topics: Abiraterone Acetate; Androgen Antagonists; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Drug Monitoring; Humans; Male; Pharmaceutical Preparations; Prostatic Neoplasms, Castration-Resistant | 2022 |
Efficacy and safety of bipolar androgen therapy in castration-resistant prostate cancer following abiraterone or enzalutamide resistance: A systematic review.
Topics: Androgens; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Quality of Life | 2022 |
Androgen receptor-related micro RNAs in prostate cancer and their role in antiandrogen drug resistance.
Topics: Androgen Antagonists; Androstenes; Benzamides; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen | 2020 |
Efficacy and safety of abiraterone and enzalutamide for castration-resistant prostate cancer: A systematic review and meta-analysis of randomized controlled trials.
Topics: Adult; Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Disease-Free Survival; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Progression-Free Survival; Proportional Hazards Models; Prostatic Neoplasms, Castration-Resistant; Randomized Controlled Trials as Topic; Treatment Outcome | 2019 |
M0CRPC overview of management options.
Topics: Androstenes; Benzamides; Clinical Trials as Topic; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Pyrazoles; Thiohydantoins | 2021 |
Corticosteroid switch after progression on abiraterone acetate plus prednisone.
Topics: Abiraterone Acetate; Adrenal Cortex Hormones; Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Humans; Male; Middle Aged; Patient Selection; Prednisolone; Prednisone; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2020 |
Combination radium-223 therapies in patients with bone metastases from castration-resistant prostate cancer: A review.
Topics: Androstenes; Antineoplastic Agents; Benzamides; Bone Density Conservation Agents; Bone Neoplasms; Docetaxel; Humans; Male; Nitriles; Orchiectomy; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Radioisotopes; Radiopharmaceuticals; Radium; Treatment Outcome; Tumor Microenvironment | 2020 |
Revealing the prognostic landscape of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in metastatic castration-resistant prostate cancer patients treated with abiraterone or enzalutamide: a meta-analysis.
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomarkers, Tumor; Blood Platelets; Humans; Lymphocytes; Male; Neutrophils; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant | 2020 |
Sequential therapy of abiraterone and enzalutamide in castration-resistant prostate cancer: a systematic review and meta-analysis.
Topics: Androgen Antagonists; Androstenes; Benzamides; Clinical Trials, Phase II as Topic; Disease Progression; Drug Administration Schedule; Humans; Kallikreins; Male; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Randomized Controlled Trials as Topic; Survival Rate; Treatment Outcome | 2020 |
Systematic Review of Efficacy and Health Economic Implications of Real-world Treatment Sequencing in Prostate Cancer: Where Do the Newer Agents Enzalutamide and Abiraterone Fit in?
Topics: Abiraterone Acetate; Androstenes; Benzamides; Humans; Male; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2021 |
Metastatic castration-resistant prostate cancer: Academic insights and perspectives through bibliometric analysis.
Topics: Androstenes; Benzamides; Bibliometrics; Bone Neoplasms; DNA Repair; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Publications; Receptors, Androgen; United Kingdom; United States; United States Food and Drug Administration | 2020 |
Molecular underpinnings of systemic treatment resistance in metastatic castration-resistant prostate cancer
Topics: Androgen Antagonists; Androstenes; Antineoplastic Agents; Benzamides; Docetaxel; Drug Resistance, Neoplasm; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Steroid 17-alpha-Hydroxylase; Treatment Outcome | 2020 |
Pharmacotherapeutic strategies for castrate-resistant prostate cancer.
Topics: Abiraterone Acetate; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Clinical Trials as Topic; Disease-Free Survival; Docetaxel; Drug Resistance, Neoplasm; Humans; Immunotherapy; Male; Nitriles; Phenylthiohydantoin; Prednisone; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant; Radium; Taxoids; Tissue Extracts | 2020 |
Comparing the clinical efficacy and safety of abiraterone and enzalutamide in metastatic castration-resistant prostate cancer: A systematic review and meta-analysis.
Topics: Aged; Androstenes; Benzamides; Cohort Studies; Humans; Male; Nitriles; Phenylthiohydantoin; Progression-Free Survival; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2021 |
Abiraterone and enzalutamide had different adverse effects on the cardiovascular system: a systematic review with pairwise and network meta-analyses.
Topics: Androstenes; Benzamides; Cardiovascular System; Humans; Male; Network Meta-Analysis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant | 2021 |
Comparison of effectiveness and safety outcomes of abiraterone versus enzalutamide in patients with metastatic castration-resistant prostate cancer: a systematic review and meta-analysis.
Topics: Androstenes; Antineoplastic Agents; Benzamides; Humans; Male; Nitriles; Phenylthiohydantoin; Progression-Free Survival; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Survival Rate; Treatment Outcome | 2020 |
Gonadotropin-Releasing Hormone Receptors in Prostate Cancer: Molecular Aspects and Biological Functions.
Topics: Androstenes; Animals; Benzamides; Docetaxel; Gonadotropin-Releasing Hormone; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Receptors, LHRH; Signal Transduction | 2020 |
Contemporary management of advanced prostate cancer: an evolving landscape.
Topics: Adenocarcinoma; Androstenes; Benzamides; Clinical Trials as Topic; Combined Modality Therapy; Diagnostic Imaging; Disease Management; Docetaxel; Humans; Male; Multicenter Studies as Topic; Nitriles; Phenylthiohydantoin; Precision Medicine; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Radiotherapy, Adjuvant; Radium; Taxoids; Therapies, Investigational | 2021 |
Quality of life in men with metastatic castration-resistant prostate cancer treated with enzalutamide or abiraterone: a systematic review and meta-analysis.
Topics: Androstenes; Benzamides; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prednisone; Prostatic Neoplasms, Castration-Resistant; Quality of Life | 2021 |
Steroid switch after progression on abiraterone plus prednisone in patients with metastatic castration-resistant prostate cancer: A systematic review.
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Humans; Male; Neoplasm Metastasis; Prednisone; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2021 |
Abiraterone-induced rhabdomyolysis resulting in acute kidney injury: A case report and review of the literature.
Topics: Acute Kidney Injury; Aged; Androstenes; Disease Progression; Fatal Outcome; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Rhabdomyolysis | 2018 |
Efficacy and safety of post-docetaxel therapies in metastatic castration-resistant prostate cancer: a systematic review of the literature.
Topics: Androstenes; Benzamides; Compassionate Use Trials; Disease-Free Survival; Docetaxel; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Randomized Controlled Trials as Topic; Taxoids; Treatment Outcome | 2017 |
The role of bone-targeted therapies for prostate cancer in 2017.
Topics: Androstenes; Antineoplastic Agents; Bone Density Conservation Agents; Bone Neoplasms; Denosumab; Diphosphonates; Drug Therapy, Combination; Humans; Imidazoles; Male; Prospective Studies; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Radium; Randomized Controlled Trials as Topic; Zoledronic Acid | 2017 |
[Splice variant AR-V7 : Is it time for its routine use as a predictive marker in prostate cancer?]
Topics: Androgens; Androstenes; Benzamides; Biomarkers, Tumor; Genetic Markers; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen; RNA, Messenger; Taxoids; Testosterone | 2017 |
[Radium-223 dichloride in patients with castration-refractory prostate cancer].
Topics: Androstenes; Benzamides; Bone Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Denosumab; Humans; Male; Neoplasm Staging; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Radioisotopes; Radium; Retreatment | 2017 |
Role of Androgen Receptor Variants in Prostate Cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting.
Topics: Aged; Androgen Antagonists; Androstenes; Benzamides; Biomarkers, Tumor; Congresses as Topic; Disease-Free Survival; Follow-Up Studies; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Risk Assessment; Survival Analysis; Treatment Outcome | 2018 |
Current approaches to incorporation of radium-223 in clinical practice.
Topics: Androstenes; Benzamides; Bone Neoplasms; Docetaxel; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Radium; Receptors, Androgen; Taxoids; Treatment Outcome | 2018 |
New Opportunities for Targeting the Androgen Receptor in Prostate Cancer.
Topics: Androgen Antagonists; Androstenes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Drug Resistance, Neoplasm; Gene Amplification; Humans; Male; Molecular Chaperones; Molecular Targeted Therapy; Mutation; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen | 2018 |
Recent advances in the management of metastatic prostate cancer: optimizing use of existing therapies, while searching for novel interventions.
Topics: Androgen Antagonists; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Humans; Male; Neoplasm Metastasis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Randomized Controlled Trials as Topic | 2018 |
Effectiveness and tolerability of targeted drugs for the treatment of metastatic castration-resistant prostate cancer: a network meta-analysis of randomized controlled trials.
Topics: Androstenes; Antineoplastic Agents; Disease-Free Survival; Humans; Male; Network Meta-Analysis; Prostatic Neoplasms, Castration-Resistant; Quinolones; Randomized Controlled Trials as Topic; Treatment Outcome | 2018 |
Treatment of hormone-naïve metastatic prostate cancer.
Topics: Androgen Antagonists; Androstenes; Clinical Trials, Phase III as Topic; Docetaxel; Drug Therapy, Combination; Humans; Male; Neoplasm Metastasis; Prospective Studies; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Randomized Controlled Trials as Topic | 2018 |
[DNA damage repair: An emerging strategy in metastatic prostate cancer].
Topics: Androstenes; Antineoplastic Agents; Benzamides; DNA Damage; DNA Repair; Docetaxel; Genomic Instability; Humans; Male; Nitriles; Phenylthiohydantoin; Poly(ADP-ribose) Polymerase Inhibitors; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2018 |
What kind of patients with castration-naïve prostate cancer can benefit from upfront docetaxel and abiraterone: A systematic review and a network meta-analysis.
Topics: Androstenes; Antineoplastic Agents; Docetaxel; Humans; Male; Network Meta-Analysis; Prostatic Neoplasms, Castration-Resistant | 2018 |
[Abiraterone in castration resistant prostate cancer.]
Topics: Androstenes; Humans; Male; Prostatic Neoplasms, Castration-Resistant | 2018 |
Androgen deprivation therapy with chemotherapy or abiraterone for patients with metastatic hormone-naive prostate cancer: a systematic review and meta-analysis.
Topics: Androgen Antagonists; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Drug Therapy, Combination; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2019 |
Germline DNA-repair Gene Mutations and Efficacy of Abiraterone or Enzalutamide in Patients with Metastatic Castration-resistant Prostate Cancer.
Topics: Androstenes; Benzamides; DNA Repair; Germ Cells; Humans; Male; Mutation; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2019 |
Optimization of therapies for men with advanced prostate cancer: a review of recent developments with a look toward the future.
Topics: Androstenes; Docetaxel; Humans; Male; Medical Oncology; Precision Medicine; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Radiotherapy; Randomized Controlled Trials as Topic | 2019 |
Metastatic castration-sensitive prostate cancer: Abiraterone, docetaxel, or….
Topics: Androstenes; Antineoplastic Agents; Docetaxel; Humans; Male; Prognosis; Prostatic Neoplasms, Castration-Resistant | 2019 |
Management of anticoagulation in patients with metastatic castration-resistant prostate cancer receiving abiraterone + prednisone.
Topics: Androstenes; Anticoagulants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Drug Interactions; Humans; Male; Prednisone; Prostatic Neoplasms, Castration-Resistant; Quality of Life; Retrospective Studies; Thrombosis; Treatment Outcome | 2019 |
Androgen receptor variant 7 (AR-V7) in sequencing therapeutic agents for castratrion resistant prostate cancer: A critical review.
Topics: Androstenes; Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Bridged-Ring Compounds; Drug Resistance, Neoplasm; Genetic Variation; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Taxoids | 2019 |
Systemic therapy in men with metastatic castration-resistant prostate cancer: a systematic review.
Topics: Androstenes; Androstenols; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Resistance, Neoplasm; Humans; Male; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Taxoids; Tissue Extracts | 2013 |
Taxane mechanisms of action: potential implications for treatment sequencing in metastatic castration-resistant prostate cancer.
Topics: Androgens; Androstenes; Androstenols; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Drug Interactions; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Signal Transduction; Taxoids | 2014 |
Beyond abiraterone: new hormonal therapies for metastatic castration-resistant prostate cancer.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Androstenes; Androstenols; Antineoplastic Agents, Hormonal; Humans; Male; Prostatic Neoplasms, Castration-Resistant | 2014 |
[Corticotherapy in castration-resistant prostate cancer].
Topics: Androstenes; Androstenols; Antineoplastic Agents; Apoptosis; Clinical Trials as Topic; Drug Therapy, Combination; Glucocorticoids; Humans; Inflammation; Male; Neovascularization, Pathologic; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Receptors, Glucocorticoid; Survival Analysis; Treatment Outcome | 2013 |
[Choice of new drugs in castration-resistant prostate cancer: predictive factors and effectiveness assessment].
Topics: Androstenes; Androstenols; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Docetaxel; Drug Resistance, Neoplasm; Evidence-Based Medicine; Humans; Male; Predictive Value of Tests; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Risk Factors; Sensitivity and Specificity; Taxoids; Treatment Outcome | 2013 |
Metastatic castration-resistant prostate cancer. Part 1: the challenges of the disease and its treatment.
Topics: Alpha Particles; Androstenes; Androstenols; Antineoplastic Agents; Benzamides; Cancer Vaccines; Chlorides; Docetaxel; Humans; Male; Mitoxantrone; Neoplasm Grading; Neoplasm Metastasis; Neoplasm Staging; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Quality of Life; Radioisotopes; Radium; Taxoids; Tissue Extracts | 2013 |
Abiraterone for treatment of metastatic castration-resistant prostate cancer: a systematic review and meta-analysis.
Topics: Androstenes; Androstenols; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Disease-Free Survival; Humans; Kallikreins; Male; Placebos; Prednisone; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant | 2014 |
Secondary hormonal manipulation in castration resistant prostate cancer.
Topics: Androgen Antagonists; Androstenes; Androstenols; Antineoplastic Agents, Hormonal; Benzamides; Drug Therapy, Combination; Humans; Male; Nitriles; Phenylthiohydantoin; Prednisone; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2014 |
Practical guide to the use of abiraterone in castration resistant prostate cancer.
Topics: Androgens; Androstenes; Androstenols; Antineoplastic Agents; Disease Progression; Humans; Male; Practice Guidelines as Topic; Prostatic Neoplasms, Castration-Resistant; Testosterone; Treatment Outcome | 2014 |
Practical guide to the use of enzalutamide.
Topics: Androgen Receptor Antagonists; Androstenes; Androstenols; Antineoplastic Agents; Benzamides; Drug Therapy, Combination; Humans; Male; Nitriles; Phenylthiohydantoin; Practice Guidelines as Topic; Prednisone; Prostatic Neoplasms, Castration-Resistant; Survival Rate; Treatment Outcome | 2014 |
[Metastatic castration-resistant prostate cancer: position paper for structured therapy monitoring].
Topics: Androstenes; Androstenols; Antineoplastic Agents; Benzamides; Disease Progression; Docetaxel; Drug Resistance, Neoplasm; Humans; Male; Neoplasm Staging; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2014 |
Targeting the androgen receptor pathway in castration-resistant prostate cancer: progresses and prospects.
Topics: Androstenes; Antineoplastic Agents; Benzamides; DNA Damage; Drug Resistance, Neoplasm; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Response Elements; Signal Transduction | 2015 |
Combined blockade of testicular and locally made androgens in prostate cancer: a highly significant medical progress based upon intracrinology.
Topics: Androgen Antagonists; Androgens; Androstenes; Androstenols; Animals; Antineoplastic Agents; Benzamides; Dehydroepiandrosterone; Endocrinology; Gonadotropin-Releasing Hormone; Humans; Male; Mutation; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostate; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Testosterone; Treatment Outcome | 2015 |
Androgen receptor splice variants in the era of enzalutamide and abiraterone.
Topics: Alternative Splicing; Androstenes; Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Benzamides; Disease Progression; Drug Resistance, Neoplasm; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen | 2014 |
Multidisciplinary consensus: a practical guide for the integration of abiraterone into clinical practice.
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Quality of Life; Treatment Outcome | 2014 |
Pathologic fracture in patients with metastatic prostate cancer.
Topics: Androstenes; Anilides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Bone Density Conservation Agents; Bone Neoplasms; Denosumab; Diphosphonates; Fractures, Spontaneous; Humans; Imidazoles; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pyridines; Radioisotopes; Radium; Zoledronic Acid | 2014 |
Targeting extra-gonadal androgens in castration-resistant prostate cancer.
Topics: Androgen Receptor Antagonists; Androgens; Androstenes; Androstenols; Benzamides; Drug Resistance, Neoplasm; Humans; Male; Mutation; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Signal Transduction; Steroids | 2015 |
[Clinical efficacy and safety of enzalutamide in metastatic castration-resistant prostate cancer: systematic review and meta-analysis].
Topics: Androstenes; Androstenols; Antineoplastic Agents; Benzamides; Bone Neoplasms; Humans; Male; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Randomized Controlled Trials as Topic; Taxoids; Treatment Outcome | 2014 |
Androgen deprivation therapy in castrate-resistant prostate cancer: how important is GnRH agonist backbone therapy?
Topics: Androstenes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Benzamides; Gonadotropin-Releasing Hormone; Humans; Leuprolide; Male; Nitriles; Orchiectomy; Phenylthiohydantoin; Practice Guidelines as Topic; Prostatic Neoplasms, Castration-Resistant; Radioisotopes; Radium; Taxoids; Tissue Extracts | 2015 |
Understanding the mechanisms of androgen deprivation resistance in prostate cancer at the molecular level.
Topics: Androgen Antagonists; Androstenes; Animals; Antineoplastic Agents, Hormonal; Benzamides; Cell Proliferation; Disease Progression; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Signal Transduction; Thiohydantoins | 2015 |
Use of prednisone with abiraterone acetate in metastatic castration-resistant prostate cancer.
Topics: Androstenes; Antineoplastic Agents, Hormonal; Disease Progression; Humans; Male; Neoplasm Metastasis; Prednisone; Prostatic Neoplasms, Castration-Resistant | 2014 |
Resistance to abiraterone in castration-resistant prostate cancer: a review of the literature.
Topics: Androstenes; Androstenols; Animals; Drug Resistance, Neoplasm; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Review Literature as Topic | 2014 |
Pharmacotherapeutic management of metastatic, castration-resistant prostate cancer in the elderly: focus on non-chemotherapy agents.
Topics: Aged; Androstenes; Benzamides; Health Services for the Aged; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Radioisotopes; Radium; Tissue Extracts | 2014 |
Metastatic castration-resistant prostate cancer: time for innovation.
Topics: Androstenes; Antibodies, Monoclonal, Humanized; Benzamides; Clinical Trials, Phase III as Topic; Denosumab; Drug Resistance, Neoplasm; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Radioisotopes; Radium; Receptors, Androgen; Signal Transduction; Taxoids; Tissue Extracts | 2015 |
Prostate cancer in 2014: The year chemotherapy finally gets some respect!
Topics: Androstenes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Benzamides; Docetaxel; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatectomy; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2015 |
Corticosteroids in the management of prostate cancer: a critical review.
Topics: Adrenal Cortex Hormones; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Resistance, Neoplasm; Humans; Male; Mitoxantrone; Palliative Care; Prednisone; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Outcome | 2015 |
[Advances in the treatment of castration-resistant prostate cancer: emphasis in new hormonal therapies].
Topics: Androstenes; Antineoplastic Agents, Hormonal; Benzamides; Biomarkers, Tumor; Disease Progression; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2015 |
Mechanisms of drug resistance that target the androgen axis in castration resistant prostate cancer (CRPC).
Topics: Androgen Receptor Antagonists; Androgens; Androstenes; Animals; Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Humans; Male; Nitriles; Phenylthiohydantoin; Prostate; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen | 2015 |
Androgen pathway resistance in prostate cancer and therapeutic implications.
Topics: Androgens; Androstenes; Benzamides; Drug Resistance, Neoplasm; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Point Mutation; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Protein Splicing; Receptors, Androgen; Signal Transduction | 2015 |
Reducing Skeletal-Related Events in Metastatic Castration-Resistant Prostate Cancer.
Topics: Androgen Receptor Antagonists; Androstenes; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Bone Density Conservation Agents; Bone Neoplasms; Cost-Benefit Analysis; Denosumab; Diphosphonates; Enzyme Inhibitors; Fractures, Spontaneous; Humans; Imidazoles; Male; Nitriles; Pain; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Quality of Life; Radioisotopes; Radium; Spinal Cord Compression; Zoledronic Acid | 2015 |
Androgen receptor aberrations in the era of abiraterone and enzalutamide.
Topics: Androstenes; Benzamides; Drug Resistance, Neoplasm; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Signal Transduction | 2016 |
Novel and next-generation androgen receptor-directed therapies for prostate cancer: Beyond abiraterone and enzalutamide.
Topics: Androgen Receptor Antagonists; Androstadienes; Androstenes; Benzamides; Benzimidazoles; Humans; Male; Naphthalenes; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Pyrazoles; Receptors, Androgen; Thiohydantoins; Triazoles | 2016 |
Treating Patients with Metastatic Castration Resistant Prostate Cancer: A Comprehensive Review of Available Therapies.
Topics: Androgen Antagonists; Androstenes; Antineoplastic Agents; Benzamides; Disease Progression; Docetaxel; Humans; Male; Neoplasm Metastasis; Neoplasm Staging; Nitriles; Orchiectomy; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Radioisotopes; Radium; Survival Rate; Taxoids; Tissue Extracts | 2015 |
[Hormone therapy in prostate cancer; a pharmacotherapeutic challenge].
Topics: Androgen Antagonists; Androstenes; Antineoplastic Agents, Hormonal; Benzamides; Disease Progression; Humans; Male; Neoplasm Metastasis; Neoplasm Recurrence, Local; Nitriles; Orchiectomy; Phenylthiohydantoin; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Quality of Life; Testosterone; Treatment Outcome | 2015 |
Sequencing new agents after docetaxel in patients with metastatic castration-resistant prostate cancer.
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Disease Progression; Docetaxel; Humans; Male; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Rate; Taxoids | 2015 |
Understanding and overcoming the mechanisms of primary and acquired resistance to abiraterone and enzalutamide in castration resistant prostate cancer.
Topics: Androgens; Androstenes; Antineoplastic Agents; Benzamides; Disease-Free Survival; Drug Resistance, Neoplasm; Gene Amplification; Humans; Male; Mutation; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Receptors, Glucocorticoid; Up-Regulation | 2015 |
New Compounds Targeting the Androgen Receptor for Treatment of Advanced Prostate Cancer.
Topics: Androstenes; Benzamides; Drug Resistance, Neoplasm; Humans; Male; Molecular Targeted Therapy; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Signal Transduction; Treatment Outcome | 2016 |
What do we know about treatment sequencing of abiraterone, enzalutamide, and chemotherapy in metastatic castration-resistant prostate cancer?
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Docetaxel; Drug Resistance, Neoplasm; Drug Therapy, Combination; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2016 |
Persistent androgen receptor addiction in castration-resistant prostate cancer.
Topics: Androgen Antagonists; Androstenes; Antineoplastic Agents; Benzamides; Feedback, Physiological; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen | 2015 |
Skeletal metastases and impact of anticancer and bone-targeted agents in patients with castration-resistant prostate cancer.
Topics: Androstenes; Anilides; Antineoplastic Agents; Benzamides; Bone Density Conservation Agents; Bone Neoplasms; Carcinoma; Dasatinib; Denosumab; Diphosphonates; Docetaxel; Humans; Imidazoles; Male; Mitoxantrone; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Pyridines; Radioisotopes; Radium; Taxoids; Zoledronic Acid | 2016 |
Targeting persistent androgen receptor signaling in castration-resistant prostate cancer.
Topics: Androgen Receptor Antagonists; Androstenes; Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Humans; Male; Molecular Targeted Therapy; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Signal Transduction | 2016 |
Differential Side Effects Profile in mCRPC Patients Treated With Abiraterone or Enzalutamide: A Meta-Analysis of Randomized Controlled Trials.
Topics: Androstenes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cardiotoxicity; Clinical Trials, Phase III as Topic; Humans; Male; Nitriles; Odds Ratio; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Randomized Controlled Trials as Topic | 2016 |
Prostate cancer: Interfering with abiraterone metabolism to optimize therapy.
Topics: Androstenes; Humans; Male; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Steroid 17-alpha-Hydroxylase | 2016 |
C-terminally truncated constitutively active androgen receptor variants and their biologic and clinical significance in castration-resistant prostate cancer.
Topics: Alternative Splicing; Androgens; Androstenes; Androstenols; Animals; Benzamides; Biomarkers, Tumor; Codon, Terminator; Disease Progression; Epithelial-Mesenchymal Transition; Genetic Variation; Genome, Human; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Protein Domains; Signal Transduction; Thiohydantoins; Transcription Factors | 2017 |
Utility of novel androgen receptor therapies in the real world: A nuanced approach.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androstenes; Antineoplastic Agents; Benzamides; Clinical Trials as Topic; Drug Resistance, Neoplasm; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen | 2016 |
[Strategies for First-Line Treatment of mCRPC].
Topics: Androstenes; Benzamides; Drug Therapy, Combination; Humans; Male; Neoplasm Staging; Nitriles; Phenylthiohydantoin; Prednisolone; Prednisone; Prostatic Neoplasms, Castration-Resistant; Survival Rate | 2016 |
Advances in the management of castration resistant prostate cancer.
Topics: Aged; Androstenes; Androstenols; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Disease Management; Docetaxel; Humans; Immunotherapy; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Randomized Controlled Trials as Topic; Risk Assessment; Survival Analysis; Taxoids; Treatment Outcome | 2016 |
Prostate cancer: What is the optimal treatment sequence for mCRPC?
Topics: Androstenes; Antineoplastic Agents; Benzamides; Clinical Trials, Phase III as Topic; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2016 |
Prostate cancer: AR aberrations and resistance to abiraterone or enzalutamide.
Topics: Androstenes; Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen | 2016 |
Abiraterone or Enzalutamide in Advanced Castration-Resistant Prostate Cancer: An Indirect Comparison.
Topics: Androstenes; Benzamides; Clinical Trials, Phase III as Topic; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Randomized Controlled Trials as Topic; Survival Rate | 2017 |
The Role of Therapeutic Layering in Optimizing Treatment for Patients With Castration-resistant Prostate Cancer (Prostate Cancer Radiographic Assessments for Detection of Advanced Recurrence II).
Topics: Androgens; Androstenes; Antineoplastic Agents; Benzamides; Clinical Trials as Topic; Disease Progression; Humans; Immunotherapy; Male; Neoplasm Metastasis; Neoplasm Recurrence, Local; Nitriles; Phenylthiohydantoin; Practice Guidelines as Topic; Prostatic Neoplasms, Castration-Resistant; Radioisotopes; Radium; Treatment Outcome | 2017 |
71 trial(s) available for abiraterone and Prostatic Neoplasms, Castration-Resistant
Article | Year |
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Comparison of out-of-pocket costs and adherence between the two arms of the prospective, randomized abiraterone food effect trial.
Topics: Androstenes; Health Expenditures; Humans; Male; Prospective Studies; Prostatic Neoplasms, Castration-Resistant | 2022 |
A phase III, randomized, open-label study (CONTACT-02) of cabozantinib plus atezolizumab versus second novel hormone therapy in patients with metastatic castration-resistant prostate cancer.
Topics: Adenocarcinoma; Androstenes; Anilides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Benzamides; Humans; Immune Checkpoint Inhibitors; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Pyridines; Receptor Protein-Tyrosine Kinases | 2022 |
Study protocol and preliminary results from a mono-centric cohort within a trial testing stereotactic body radiotherapy and abiraterone (ARTO-NCT03449719).
Topics: Abiraterone Acetate; Androstenes; Chemoradiotherapy; Clinical Trial Protocols as Topic; Cohort Studies; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Quality of Life; Radiosurgery; Treatment Outcome | 2022 |
Patient-reported outcomes with olaparib plus abiraterone versus placebo plus abiraterone for metastatic castration-resistant prostate cancer: a randomised, double-blind, phase 2 trial.
Topics: Androgen Antagonists; Androgens; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Double-Blind Method; Humans; Male; Pain; Patient Reported Outcome Measures; Phthalazines; Piperazines; Prednisolone; Prednisone; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Quality of Life; Testosterone | 2022 |
A Phase II Trial of Abiraterone With Dutasteride for Second-Generation Antiandrogen- and Chemotherapy-Naïve Patients With Castration-Resistant Prostate Cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Abiraterone Acetate; Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Dutasteride; Humans; Male; Membrane Proteins; Multienzyme Complexes; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2023 |
Safety Profile of Ipatasertib Plus Abiraterone vs Placebo Plus Abiraterone in Metastatic Castration-resistant Prostate Cancer.
Topics: Abiraterone Acetate; Antineoplastic Combined Chemotherapy Protocols; Exanthema; Humans; Hyperglycemia; Male; Prednisolone; Prednisone; Prostatic Neoplasms, Castration-Resistant | 2023 |
Rucaparib or Physician's Choice in Metastatic Prostate Cancer.
Topics: Androgen Antagonists; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Docetaxel; Genes, BRCA1; Genes, BRCA2; Humans; Indoles; Male; Poly(ADP-ribose) Polymerase Inhibitors; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant | 2023 |
Randomized Phase III Study of Enzalutamide Compared With Enzalutamide Plus Abiraterone for Metastatic Castration-Resistant Prostate Cancer (Alliance A031201 Trial).
Topics: Abiraterone Acetate; Antineoplastic Combined Chemotherapy Protocols; Humans; Male; Nitriles; Prednisone; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2023 |
Fatigue, quality of life and metabolic changes in men treated with first-line enzalutamide versus abiraterone plus prednisolone for metastatic castration-resistant prostate cancer (HEAT): a randomised trial protocol.
Topics: Androgen Antagonists; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Blood Glucose; Clinical Trials, Phase III as Topic; Denmark; Fatigue; Humans; Male; Neoplasm Invasiveness; Neoplasm Staging; Nitriles; Phenylthiohydantoin; Prednisolone; Prostatic Neoplasms, Castration-Resistant; Quality of Life; Randomized Controlled Trials as Topic; Risk Assessment; Survival Analysis; Treatment Outcome | 2019 |
Cabazitaxel versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prednisone; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2019 |
PSMA ADC monotherapy in patients with progressive metastatic castration-resistant prostate cancer following abiraterone and/or enzalutamide: Efficacy and safety in open-label single-arm phase 2 study.
Topics: Aged; Aged, 80 and over; Androstenes; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomarkers, Tumor; Drug Resistance, Neoplasm; Humans; Immunotoxins; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Survival Rate; Treatment Outcome | 2020 |
Methylation of SRD5A2 promoter predicts a better outcome for castration-resistant prostate cancer patients undergoing androgen deprivation therapy.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androstenes; DNA Methylation; Dutasteride; Epigenesis, Genetic; Humans; Male; Membrane Proteins; Prognosis; Promoter Regions, Genetic; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2020 |
Olaparib for Metastatic Castration-Resistant Prostate Cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Benzamides; Genes, BRCA1; Genes, BRCA2; Humans; Loss of Function Mutation; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant | 2020 |
HSD3B1 (1245A>C) germline variant and clinical outcomes in metastatic castration-resistant prostate cancer patients treated with abiraterone and enzalutamide: results from two prospective studies.
Topics: Abiraterone Acetate; Androgen Antagonists; Androstenes; Benzamides; Germ Cells; Humans; Male; Multienzyme Complexes; Nitriles; Phenylthiohydantoin; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2020 |
A Multicohort Open-label Phase II Trial of Bipolar Androgen Therapy in Men with Metastatic Castration-resistant Prostate Cancer (RESTORE): A Comparison of Post-abiraterone Versus Post-enzalutamide Cohorts.
Topics: Androgens; Androstenes; Benzamides; Humans; Male; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Testosterone | 2021 |
A Phase 2 Trial of Abiraterone Followed by Randomization to Addition of Dasatinib or Sunitinib in Men With Metastatic Castration-Resistant Prostate Cancer.
Topics: Abiraterone Acetate; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Dasatinib; Humans; Male; Prednisone; Prostatic Neoplasms, Castration-Resistant; Random Allocation; Sunitinib; Treatment Outcome; Tumor Microenvironment | 2021 |
A Phase Ib/IIa Study of the Pan-BET Inhibitor ZEN-3694 in Combination with Enzalutamide in Patients with Metastatic Castration-resistant Prostate Cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Disease-Free Survival; Drug Resistance, Neoplasm; Humans; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Treatment Outcome | 2020 |
Quality of life in patients with metastatic prostate cancer following treatment with cabazitaxel versus abiraterone or enzalutamide (CARD): an analysis of a randomised, multicentre, open-label, phase 4 study.
Topics: Aged; Androgen Antagonists; Androgens; Androstenes; Benzamides; Disease-Free Survival; Humans; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Quality of Life; Taxoids; Treatment Outcome | 2020 |
Phase Ib trial of reformulated niclosamide with abiraterone/prednisone in men with castration-resistant prostate cancer.
Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Drug-Related Side Effects and Adverse Reactions; Humans; Male; Maximum Tolerated Dose; Middle Aged; Niclosamide; Prednisone; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant | 2021 |
Niraparib with androgen receptor-axis-targeted therapy in patients with metastatic castration-resistant prostate cancer: safety and pharmacokinetic results from a phase 1b study (BEDIVERE).
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Humans; Indazoles; Male; Middle Aged; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Prednisone; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Thiohydantoins | 2021 |
Phase I Study of MEDI3726: A Prostate-Specific Membrane Antigen-Targeted Antibody-Drug Conjugate, in Patients with mCRPC after Failure of Abiraterone or Enzalutamide.
Topics: Aged; Aged, 80 and over; Androstenes; Antigens, Surface; Benzamides; Glutamate Carboxypeptidase II; Humans; Immunoconjugates; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Treatment Failure | 2021 |
Cabazitaxel versus abiraterone or enzalutamide in poor prognosis metastatic castration-resistant prostate cancer: a multicentre, randomised, open-label, phase II trial.
Topics: Androgen Antagonists; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Humans; Male; Nitriles; Phenylthiohydantoin; Prednisone; Prognosis; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Outcome | 2021 |
Ipatasertib plus abiraterone and prednisolone in metastatic castration-resistant prostate cancer (IPATential150): a multicentre, randomised, double-blind, phase 3 trial.
Topics: Aged; Androstenes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Double-Blind Method; Humans; Male; Piperazines; Prednisolone; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant; Pyrimidines | 2021 |
Efficacy and Safety of Cabazitaxel Versus Abiraterone or Enzalutamide in Older Patients with Metastatic Castration-resistant Prostate Cancer in the CARD Study.
Topics: Abiraterone Acetate; Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Disease-Free Survival; Docetaxel; Humans; Male; Nitriles; Phenylthiohydantoin; Prednisone; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Outcome | 2021 |
Loss of
Topics: Aged; Androgen Antagonists; Androstenes; Anilides; Antineoplastic Agents, Hormonal; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Male; Nitriles; Oligopeptides; Prostatic Neoplasms, Castration-Resistant; Signal Transduction; Snail Family Transcription Factors; Tosyl Compounds | 2021 |
Circulating and Intratumoral Adrenal Androgens Correlate with Response to Abiraterone in Men with Castration-Resistant Prostate Cancer.
Topics: Adrenal Cortex; Adult; Aged; Aged, 80 and over; Androgens; Androstenes; Antineoplastic Agents, Hormonal; Correlation of Data; Drug Combinations; Humans; Male; Middle Aged; Neoplasm Metastasis; Prednisone; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2021 |
Baseline neutrophil-to-lymphocyte ratio as a predictive and prognostic biomarker in patients with metastatic castration-resistant prostate cancer treated with cabazitaxel versus abiraterone or enzalutamide in the CARD study.
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Humans; Lymphocytes; Male; Neutrophils; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2021 |
Androgen receptor gene status in plasma DNA associates with worse outcome on enzalutamide or abiraterone for castration-resistant prostate cancer: a multi-institution correlative biomarker study.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents, Hormonal; Benzamides; Biomarkers, Tumor; Circulating Tumor DNA; Disease Progression; Disease-Free Survival; DNA Mutational Analysis; Europe; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Multiplex Polymerase Chain Reaction; Multivariate Analysis; Mutation; Nitriles; Odds Ratio; Patient Selection; Phenylthiohydantoin; Precision Medicine; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Risk Factors; Time Factors; Treatment Outcome | 2017 |
Androgen Receptor Variant AR-V9 Is Coexpressed with AR-V7 in Prostate Cancer Metastases and Predicts Abiraterone Resistance.
Topics: Androstenes; Cell Line, Tumor; Cell Proliferation; Disease-Free Survival; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genetic Variation; Humans; Male; Neoplasm Metastasis; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen; RNA Interference | 2017 |
High-Dose Abiraterone Acetate in Men With Castration Resistant Prostate Cancer.
Topics: Aged; Androstenes; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Neoplasm; Humans; Male; Middle Aged; Prednisone; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2017 |
Activity of cabazitaxel in patients with metastatic castration-resistant prostate cancer after treatment with single or dual regimens of novel androgen receptor-targeting agents.
Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Disease-Free Survival; Docetaxel; Humans; Male; Molecular Targeted Therapy; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Taxoids; Treatment Outcome | 2017 |
Enzalutamide versus abiraterone as a first-line endocrine therapy for castration-resistant prostate cancer (ENABLE study for PCa): a study protocol for a multicenter randomized phase III trial.
Topics: Adult; Aged; Androstenes; Benzamides; Disease Progression; Disease-Free Survival; Docetaxel; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2017 |
Platelets harbor prostate cancer biomarkers and the ability to predict therapeutic response to abiraterone in castration resistant patients.
Topics: Aged; Androstenes; Antineoplastic Agents; Biomarkers, Tumor; Blood Platelets; Disease-Free Survival; Docetaxel; Glutamate Carboxypeptidase II; Humans; Kallikreins; Male; Middle Aged; Neuropeptide Y; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Outcome | 2018 |
Prognostic value of 18F-choline PET/CT metabolic parameters in patients with metastatic castration-resistant prostate cancer treated with abiraterone or enzalutamide.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Benzamides; Choline; Humans; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Positron Emission Tomography Computed Tomography; Prognosis; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Reproducibility of Results; Retrospective Studies | 2018 |
Integrating evolutionary dynamics into treatment of metastatic castrate-resistant prostate cancer.
Topics: Androgens; Androstenes; Disease Progression; Humans; Male; Models, Theoretical; Neoplasm Metastasis; Pilot Projects; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Steroid 17-alpha-Hydroxylase; Testosterone; Time Factors; Treatment Failure; Treatment Outcome | 2017 |
Population-based Analysis of Treatment Toxicity Among Men With Castration-resistant Prostate Cancer: A Phase IV Study.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Canada; Cohort Studies; Docetaxel; Dose-Response Relationship, Drug; Drug Administration Schedule; Emergency Service, Hospital; Hospitalization; Humans; Kaplan-Meier Estimate; Male; Maximum Tolerated Dose; Multivariate Analysis; Nitriles; Ontario; Phenylthiohydantoin; Population Surveillance; Prognosis; Proportional Hazards Models; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Risk Assessment; Survival Analysis; Taxoids; Treatment Outcome | 2018 |
Targeting Androgen Receptor and DNA Repair in Metastatic Castration-Resistant Prostate Cancer: Results From NCI 9012.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Biomarkers, Tumor; DNA Repair; Humans; Male; Middle Aged; Molecular Targeted Therapy; Neoplasm Metastasis; Poly(ADP-ribose) Polymerase Inhibitors; Prednisone; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-ets; Receptors, Androgen | 2018 |
A Phase II Trial of Selinexor, an Oral Selective Inhibitor of Nuclear Export Compound, in Abiraterone- and/or Enzalutamide-Refractory Metastatic Castration-Resistant Prostate Cancer.
Topics: Aged; Androstenes; Benzamides; Humans; Hydrazines; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Triazoles | 2018 |
Prospective International Randomized Phase II Study of Low-Dose Abiraterone With Food Versus Standard Dose Abiraterone In Castration-Resistant Prostate Cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Biomarkers, Tumor; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Fasting; Food; Glucocorticoids; Humans; Male; Middle Aged; Prednisone; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Singapore; Testosterone; Treatment Outcome; United States | 2018 |
Circulating tumour cell increase as a biomarker of disease progression in metastatic castration-resistant prostate cancer patients with low baseline CTC counts.
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Disease Progression; Follow-Up Studies; Humans; Male; Neoplasm Metastasis; Neoplastic Cells, Circulating; Prednisone; Prognosis; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Survival Rate | 2018 |
Intense Exercise for Survival among Men with Metastatic Castrate-Resistant Prostate Cancer (INTERVAL-GAP4): a multicentre, randomised, controlled phase III study protocol.
Topics: Androgen Antagonists; Androstenes; Benzamides; Clinical Trials, Phase III as Topic; Disease Progression; Exercise Therapy; Humans; Male; Multicenter Studies as Topic; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Quality of Life; Randomized Controlled Trials as Topic; Receptors, Androgen; United States | 2018 |
Olaparib combined with abiraterone in patients with metastatic castration-resistant prostate cancer: a randomised, double-blind, placebo-controlled, phase 2 trial.
Topics: Age Factors; Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Phthalazines; Piperazines; Prognosis; Proportional Hazards Models; Prostatic Neoplasms, Castration-Resistant; Risk Assessment; Survival Rate; Treatment Outcome | 2018 |
Abiraterone Alone or in Combination With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer With Rising Prostate-Specific Antigen During Enzalutamide Treatment.
Topics: Androstenes; Antineoplastic Agents; Benzamides; Double-Blind Method; Drug Resistance, Neoplasm; Humans; Hypertension; Liver; Male; Nitriles; Phenylthiohydantoin; Progression-Free Survival; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2018 |
Randomized Phase II Study Evaluating Akt Blockade with Ipatasertib, in Combination with Abiraterone, in Patients with Metastatic Prostate Cancer with and without PTEN Loss.
Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Double-Blind Method; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Mutation; Neoplasm Metastasis; Piperazines; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyrimidines; Treatment Outcome | 2019 |
Phase II pilot study of the prednisone to dexamethasone switch in metastatic castration-resistant prostate cancer (mCRPC) patients with limited progression on abiraterone plus prednisone (SWITCH study).
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents, Hormonal; Dexamethasone; Disease Progression; Humans; Male; Middle Aged; Oncogene Proteins, Fusion; Pilot Projects; Prednisone; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; PTEN Phosphohydrolase; Receptors, Androgen; Survival Analysis; Treatment Outcome | 2018 |
Enzalutamide after chemotherapy in advanced castration-resistant prostate cancer: the Italian Named Patient Program.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Disease Progression; Docetaxel; Drug Resistance, Neoplasm; Humans; Italy; Kallikreins; Kaplan-Meier Estimate; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Progression-Free Survival; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies | 2018 |
Topics: Aged; Aged, 80 and over; Androgen Receptor Antagonists; Androstenes; Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Circulating Tumor DNA; Disease-Free Survival; Drug Resistance, Neoplasm; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Liquid Biopsy; Male; Neoplastic Cells, Circulating; Nitriles; Phenylthiohydantoin; Predictive Value of Tests; Prognosis; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; RNA-Seq; Tumor Suppressor Protein p53 | 2019 |
Health-related Quality of Life for Abiraterone Plus Prednisone Versus Enzalutamide in Patients with Metastatic Castration-resistant Prostate Cancer: Results from a Phase II Randomized Trial.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prednisone; Prostatic Neoplasms, Castration-Resistant; Quality of Life | 2019 |
Radium-223 in asymptomatic patients with castration-resistant prostate cancer and bone metastases treated in an international early access program.
Topics: Aged; Aged, 80 and over; Androstenes; Bone Neoplasms; Disease Progression; Disease-Free Survival; Docetaxel; Drug-Related Side Effects and Adverse Reactions; Humans; Male; Middle Aged; Neoplasm Metastasis; Proportional Hazards Models; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Radioisotopes; Radium; Treatment Outcome | 2019 |
Prospective Multicenter Validation of Androgen Receptor Splice Variant 7 and Hormone Therapy Resistance in High-Risk Castration-Resistant Prostate Cancer: The PROPHECY Study.
Topics: Aged; Aged, 80 and over; Androstenes; Benzamides; Humans; Male; Middle Aged; Neoplastic Cells, Circulating; Nitriles; Phenylthiohydantoin; Predictive Value of Tests; Progression-Free Survival; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen; Reproducibility of Results; Treatment Outcome | 2019 |
Androgen Receptor Burden and Poor Response to Abiraterone or Enzalutamide in TP53 Wild-Type Metastatic Castration-Resistant Prostate Cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen; Treatment Outcome; Tumor Suppressor Protein p53 | 2019 |
A Phase II Study of PX-866 in Patients With Recurrent or Metastatic Castration-resistant Prostate Cancer: Canadian Cancer Trials Group Study IND205.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Canada; Disease Progression; Gonanes; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplastic Cells, Circulating; Prostatic Neoplasms, Castration-Resistant; PTEN Phosphohydrolase; Survival Analysis; Treatment Outcome | 2019 |
Randomized Phase II Trial of Abiraterone Alone or With Dasatinib in Men With Metastatic Castration-resistant Prostate Cancer (mCRPC).
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Dasatinib; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Humans; Male; Middle Aged; Neoplastic Cells, Circulating; Prostatic Neoplasms, Castration-Resistant; Protein Kinase Inhibitors; Treatment Outcome | 2019 |
Androgen dynamics and serum PSA in patients treated with abiraterone acetate.
Topics: Abiraterone Acetate; Androgens; Androstenes; Double-Blind Method; Humans; Kallikreins; Male; Prednisone; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Testosterone; Treatment Outcome | 2014 |
External validation of a prognostic model predicting overall survival in metastatic castrate-resistant prostate cancer patients treated with abiraterone.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Androstenols; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Docetaxel; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Metastasis; Prognosis; Proportional Hazards Models; Prostatic Neoplasms, Castration-Resistant; ROC Curve; Survival Rate; Taxoids; Time Factors | 2014 |
Impact of baseline corticosteroids on survival and steroid androgens in metastatic castration-resistant prostate cancer: exploratory analysis from COU-AA-301.
Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Docetaxel; Humans; Male; Middle Aged; Neoplasm Metastasis; Prednisone; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Risk Factors; Survival Analysis; Taxoids | 2015 |
Imaging, procedural and clinical variables associated with tumor yield on bone biopsy in metastatic castration-resistant prostate cancer.
Topics: Aged; Androgen Antagonists; Androstenes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Azasteroids; Biopsy; Bone Neoplasms; Drug Resistance, Neoplasm; Dutasteride; Humans; Male; Middle Aged; Prostatic Neoplasms, Castration-Resistant; Radiography, Interventional; Radionuclide Imaging; Radiopharmaceuticals; Surgery, Computer-Assisted; Technetium Tc 99m Medronate | 2014 |
Abiraterone acetate and prednisolone for metastatic castration-resistant prostate cancer failing androgen deprivation and docetaxel-based chemotherapy: a phase II bridging study in Korean and Taiwanese patients.
Topics: Aged; Androgens; Androstenes; Antineoplastic Agents; Disease Progression; Docetaxel; Drug Therapy, Combination; Glucocorticoids; Humans; Incidence; Male; Orchiectomy; Prednisolone; Prostatic Neoplasms, Castration-Resistant; Republic of Korea; Survival Rate; Taiwan; Taxoids; Treatment Failure | 2014 |
Phase-1 study of abiraterone acetate in chemotherapy-naïve Japanese patients with castration-resistant prostate cancer.
Topics: Abiraterone Acetate; Aged; Aged, 80 and over; Androstadienes; Androstenes; Androstenols; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Steroid 17-alpha-Hydroxylase | 2014 |
Population pharmacokinetic analysis of abiraterone in chemotherapy-naïve and docetaxel-treated patients with metastatic castration-resistant prostate cancer.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Biological Availability; Cross-Over Studies; Dietary Fats; Docetaxel; Double-Blind Method; Fasting; Food-Drug Interactions; Healthy Volunteers; Humans; Male; Middle Aged; Models, Biological; Prostatic Neoplasms, Castration-Resistant; Steroid 17-alpha-Hydroxylase; Taxoids; Young Adult | 2014 |
Abiraterone acetate for patients with metastatic castration-resistant prostate cancer progressing after chemotherapy: final analysis of a multicentre, open-label, early-access protocol trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Androgen Antagonists; Androstenes; Androstenols; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasm Staging; Prednisolone; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Survival Analysis; Treatment Outcome | 2014 |
[Recruiting participants - study of therapy of CRPC].
Topics: Adenocarcinoma; Androgen Antagonists; Androstenes; Biomarkers, Tumor; Disease Progression; Drug Therapy, Combination; Germany; Gonadotropin-Releasing Hormone; Humans; Male; Patient Selection; Prednisone; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant | 2014 |
A phase 2 study of abiraterone acetate in Japanese men with metastatic castration-resistant prostate cancer who had received docetaxel-based chemotherapy.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Humans; Male; Middle Aged; Neoplasm Metastasis; Prednisolone; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2014 |
Early outcome prediction on 18F-fluorocholine PET/CT in metastatic castration-resistant prostate cancer patients treated with abiraterone.
Topics: Aged; Androstenes; Antineoplastic Agents; Choline; Disease-Free Survival; Drug Resistance, Neoplasm; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Multimodal Imaging; Positron-Emission Tomography; Prostatic Neoplasms, Castration-Resistant; Radioisotopes; Tomography, X-Ray Computed | 2014 |
Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3 study
Topics: Aged; Androstenes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Disease Progression; Double-Blind Method; Follow-Up Studies; Humans; Male; Neoplasm Staging; Prednisone; Prognosis; Prostatic Neoplasms, Castration-Resistant; Survival Rate | 2015 |
Hematologic Toxicity of Concurrent Administration of Radium-223 and Next-generation Antiandrogen Therapies.
Topics: Aged; Androgen Antagonists; Androstenes; Antineoplastic Agents; Benzamides; Blood Cells; Combined Modality Therapy; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Radium; Retrospective Studies; Treatment Outcome | 2017 |
The influence of prior novel androgen receptor targeted therapy on the efficacy of cabazitaxel in men with metastatic castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Disease-Free Survival; Docetaxel; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Molecular Targeted Therapy; Multivariate Analysis; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Taxoids; Treatment Outcome | 2015 |
High subcutaneous adipose tissue predicts the prognosis in metastatic castration-resistant prostate cancer patients in post chemotherapy setting.
Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Disease-Free Survival; Double-Blind Method; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Outcome Assessment, Health Care; Phenylthiohydantoin; Prognosis; Proportional Hazards Models; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Subcutaneous Fat | 2015 |
A Phase II Trial of Abiraterone Combined with Dutasteride for Men with Metastatic Castration-Resistant Prostate Cancer.
Topics: Aged; Androgens; Androstenes; Disease Progression; Drug Resistance, Neoplasm; Dutasteride; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Radiography; Receptors, Androgen | 2017 |
Phase I/II trial of cabazitaxel plus abiraterone in patients with metastatic castration-resistant prostate cancer (mCRPC) progressing after docetaxel and abiraterone.
Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Disease-Free Survival; Docetaxel; Humans; Kaplan-Meier Estimate; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Outcome | 2017 |
A Phase I/II Study of the Investigational Drug Alisertib in Combination With Abiraterone and Prednisone for Patients With Metastatic Castration-Resistant Prostate Cancer Progressing on Abiraterone.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Azepines; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Prednisone; Prostatic Neoplasms, Castration-Resistant; Pyrimidines; Testosterone | 2016 |
350 other study(ies) available for abiraterone and Prostatic Neoplasms, Castration-Resistant
Article | Year |
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Discovery and biological evaluation of novel androgen receptor antagonist for castration-resistant prostate cancer.
Topics: Androgen Receptor Antagonists; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Male; Models, Molecular; Molecular Structure; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Structure-Activity Relationship; Tumor Cells, Cultured | 2019 |
Development of Novel AKR1C3 Inhibitors as New Potential Treatment for Castration-Resistant Prostate Cancer.
Topics: Aldo-Keto Reductase Family 1 Member C3; Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Drug Design; Enzyme Inhibitors; G1 Phase Cell Cycle Checkpoints; Humans; Male; Mice, Inbred BALB C; PC-3 Cells; Prostatic Neoplasms, Castration-Resistant; Xenograft Model Antitumor Assays | 2020 |
Discovery and Structure-Based Optimization of Novel Atg4B Inhibitors for the Treatment of Castration-Resistant Prostate Cancer.
Topics: Apoptosis; Autophagy; Autophagy-Related Proteins; Cell Line, Tumor; Cysteine Endopeptidases; Humans; Male; Prostatic Neoplasms, Castration-Resistant | 2022 |
Design, Synthesis, and Biological Evaluation of Androgen Receptor Degrading and Antagonizing Bifunctional Steroidal Analogs for the Treatment of Advanced Prostate Cancer.
Topics: Androgen Receptor Antagonists; Cell Line, Tumor; Cell Proliferation; Hormones; Humans; Male; Nitriles; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen | 2022 |
Risk for stroke and myocardial infarction with abiraterone versus enzalutamide in metastatic prostate cancer patients.
Topics: Adult; Androgen Antagonists; Androstenes; Benzamides; Humans; Male; Myocardial Infarction; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Stroke | 2021 |
Time on treatment with abiraterone and enzalutamide in the Patient-overview Prostate Cancer in The National Prostate Cancer Register of Sweden.
Topics: Aged; Androstenes; Benzamides; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Sweden; Treatment Outcome | 2021 |
Real-world outcomes of abiraterone and enzalutamide in first-line treatment of metastatic castration-resistant prostate cancer: which patients benefit most?
Topics: Alkaline Phosphatase; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies | 2023 |
Treatment with abiraterone or enzalutamide does not impair immunological response to COVID-19 vaccination in prostate cancer patients.
Topics: Androstenes; Antineoplastic Agents; Benzamides; COVID-19; COVID-19 Vaccines; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; SARS-CoV-2; Treatment Outcome; Vaccination | 2022 |
Overcoming enzalutamide resistance in metastatic prostate cancer by targeting sphingosine kinase.
Topics: Aged; Aged, 80 and over; Androstenes; Benzamides; Biomarkers, Tumor; Cell Line, Tumor; Ceramides; Circulating Tumor DNA; Drug Resistance, Neoplasm; Humans; Lysophospholipids; Male; Nitriles; Phenylthiohydantoin; Phosphotransferases (Alcohol Group Acceptor); Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Signal Transduction; Sphingosine | 2021 |
Survival by race in men with chemotherapy-naive enzalutamide- or abiraterone-treated metastatic castration-resistant prostate cancer.
Topics: Adolescent; Adult; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2022 |
Comparison of clinical outcomes between androgen deprivation therapy with up-front abiraterone and bicalutamide for Japanese patients with LATITUDE high-risk prostate cancer in a real-world retrospective analysis.
Topics: Abiraterone Acetate; Androgen Antagonists; Androgens; Androstenes; Anilides; Antineoplastic Combined Chemotherapy Protocols; Humans; Japan; Male; Neoplasm Recurrence, Local; Nitriles; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Tosyl Compounds | 2022 |
Overall and progression-free survival of Afro-Caribbean men with metastatic castration-resistant prostate cancer (mCRPC).
Topics: Androstenes; Antineoplastic Agents; Benzamides; Black People; Docetaxel; Guadeloupe; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Nitriles; Phenylthiohydantoin; Progression-Free Survival; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2022 |
Outcomes Among African American and Non-Hispanic White Men With Metastatic Castration-Resistant Prostate Cancer With First-Line Abiraterone.
Topics: Aged; Androstenes; Antineoplastic Agents; Benzamides; Black or African American; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome; White People | 2022 |
Potential and real drug interactions in patients treated with abiraterone or enzalutamide in clinical practice.
Topics: Abiraterone Acetate; Androstenes; Benzamides; Cross-Sectional Studies; Drug Interactions; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2021 |
Abiraterone switches castration-resistant prostate cancer dependency from adrenal androgens towards androgen receptor variants and glucocorticoid receptor signalling.
Topics: Androgens; Androstenes; Animals; Cell Line, Tumor; Humans; Ligands; Male; Mice; Nitriles; Orchiectomy; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Receptors, Glucocorticoid | 2022 |
Potential negative pharmacodynamic interaction of spironolactone and abiraterone in two prostate cancer patients.
Topics: Abiraterone Acetate; Antineoplastic Combined Chemotherapy Protocols; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Spironolactone; Treatment Outcome | 2022 |
Prognostic role of platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio in patients with metastatic castration resistant prostate cancer treated with abiraterone or enzalutamide.
Topics: Androstenes; Benzamides; Humans; Lymphocytes; Male; Neutrophils; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant | 2021 |
Real-world survival outcomes of adding docetaxel or abiraterone in patients with high-volume metastatic castration-sensitive prostate cancer: historically controlled, propensity score matched comparison with androgen deprivation therapy.
Topics: Androgen Antagonists; Androgens; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Castration; Docetaxel; Humans; Male; Propensity Score; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies | 2022 |
Biomarkers for Predicting Abiraterone Treatment Outcome and Selecting Alternative Therapies in Castration-Resistant Prostate Cancer.
Topics: Androstenes; Biomarkers; Complementary Therapies; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2022 |
Risk of Metabolic and Cardiovascular Adverse Events With Abiraterone or Enzalutamide Among Men With Advanced Prostate Cancer.
Topics: Aged; Androstenes; Benzamides; Humans; Male; Medicare; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome; United States | 2022 |
Ascending Flaccid Paralysis Secondary to Hypokalemia in A Cancer Patient using Abiraterone - A Case Report.
Topics: Abiraterone Acetate; Antineoplastic Combined Chemotherapy Protocols; Humans; Hypokalemia; Male; Paralysis; Prednisone; Prostatic Neoplasms, Castration-Resistant | 2023 |
Impact of Novel Hormonal Agents (Abiraterone, Enzalutamide) on the Development of Visceral and/or Brain Metastases in Patients With Bone-metastatic Castration-resistant Prostate Cancer.
Topics: Abiraterone Acetate; Aged; Androstenes; Benzamides; Brain Neoplasms; Docetaxel; Humans; Male; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2022 |
Management of prostate cancer by targeting 3βHSD1 after enzalutamide and abiraterone treatment.
Topics: Androstenes; Benzamides; Drug Resistance, Neoplasm; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant | 2022 |
Immediate Prostate-specific Antigen Decline After Enzalutamide Following Abiraterone Predicts Survival in Castration-resistant Disease.
Topics: Androstenes; Benzamides; Docetaxel; Humans; Male; Nitriles; Orchiectomy; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Outcome | 2022 |
Serum prolactin level as a predictive factor for abiraterone response in patients with metastatic castration-resistant prostate cancer.
Topics: Abiraterone Acetate; Androstenes; Humans; Male; Prolactin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2022 |
Skeletal-related events after abiraterone or enzalutamide in patients with metastatic castration-resistant prostate cancer: A population-based study using the SEER-Medicare linked dataset.
Topics: Abiraterone Acetate; Aged; Androstenes; Benzamides; Denosumab; Humans; Male; Medicare; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome; United States | 2022 |
A scoping review protocol to elucidate outcomes following abiraterone versus enzalutamide for prostate cancer.
Topics: Abiraterone Acetate; Androstenes; Benzamides; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Review Literature as Topic; Treatment Outcome | 2022 |
Changes in prostate-specific antigen kinetics during androgen-deprivation therapy as a predictor of response to abiraterone in chemonaïve patients with metastatic castration-resistant prostate cancer.
Topics: Abiraterone Acetate; Aged; Androgen Antagonists; Androgens; Androstenes; Humans; Kinetics; Male; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2022 |
Survival of veterans treated with enzalutamide and abiraterone for metastatic castrate resistant prostate cancer based on comorbid diseases.
Topics: Abiraterone Acetate; Cardiovascular Diseases; Diabetes Mellitus; Humans; Male; Nitriles; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome; Veterans | 2023 |
Molecular Profile Changes in Patients with Castrate-Resistant Prostate Cancer Pre- and Post-Abiraterone/Prednisone Treatment.
Topics: Abiraterone Acetate; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Humans; Male; Prednisone; Prostatic Neoplasms, Castration-Resistant | 2022 |
Remission of progressive metastatic castration-resistant prostate cancer during abiraterone therapy following unilateral adrenalectomy for a functioning adrenal adenoma.
Topics: Abiraterone Acetate; Adrenalectomy; Aldosterone; Androgens; Androstenes; Humans; Male; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Testosterone; Treatment Outcome | 2022 |
Correlation Between Trough Level of Abiraterone and Prostate-Specific Antigen (PSA) Response in Metastatic Hormone-Sensitive Prostate Cancer.
Topics: Abiraterone Acetate; Androstenes; Dihydrotestosterone; Humans; Male; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Steroid 17-alpha-Hydroxylase; Testosterone; Treatment Outcome | 2022 |
Long-term use and risk of major adverse cardiac events: Comparing enzalutamide and abiraterone in chemotherapy-naïve patients with metastatic castration-resistant prostate cancer.
Topics: Cardiovascular Diseases; Humans; Male; Nitriles; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2023 |
Stereotactic body radiotherapy in oligoprogressive metastatic castration-resistant prostate cancer during abiraterone or enzalutamide.
Topics: Antineoplastic Agents; Humans; Male; Nitriles; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Radiosurgery; Receptors, Androgen; Retrospective Studies; Treatment Outcome | 2023 |
Impact of trough abiraterone level on adverse events in patients with prostate cancer treated with abiraterone acetate.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Abiraterone Acetate; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Humans; Male; Membrane Proteins; Prospective Studies; Prostatic Neoplasms, Castration-Resistant | 2023 |
Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling.
Topics: Androgens; Animals; Humans; Male; Mice; Mitosis; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen | 2023 |
Comparison of efficacy and medical costs between upfront docetaxel and abiraterone treatments of metastatic hormone-sensitive prostate cancer patients in real-world practice: a multicenter retrospective study.
Topics: Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Hormones; Humans; Male; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2023 |
Qi Ling decoction enhances abiraterone treatment via suppression of autophagy in castration resistant prostate cancer.
Topics: Androstenes; Autophagy; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Qi | 2022 |
Should one use the combination of abiraterone and poly(ADP-ribose) polymerase inhibitors as first-line therapy for all patients with metastatic castration-resistant prostate cancer?
Topics: Androstenes; DNA Repair; Humans; Male; Poly(ADP-ribose) Polymerase Inhibitors; Prostatic Neoplasms, Castration-Resistant | 2022 |
Docetaxel versus abiraterone for metastatic hormone-sensitive prostate cancer with focus on efficacy of sequential therapy.
Topics: Androgen Antagonists; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Hormones; Humans; Male; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2023 |
Plasma extracellular vesicle circRNA signature and resistance to abiraterone in metastatic castration-resistant prostate cancer.
Topics: Abiraterone Acetate; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; RNA, Circular; Treatment Outcome | 2023 |
Circulating tumor cell quantification during abiraterone plus prednisone therapy may estimate survival in metastatic castration-resistant prostate cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Disease-Free Survival; Humans; Male; Neoplastic Cells, Circulating; Prednisone; Prostatic Neoplasms, Castration-Resistant | 2023 |
Abiraterone-Docetaxel scheduling for metastatic castration-resistant prostate cancer based on evolutionary dynamics.
Topics: Abiraterone Acetate; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Taxoids; Treatment Outcome | 2023 |
[Drug approval: Olaparib in combination with abiraterone for metastatic castration-resistant prostate cancer].
Topics: Abiraterone Acetate; Antineoplastic Agents; Drug Approval; Humans; Male; Prostatic Neoplasms, Castration-Resistant | 2023 |
PSMA-positive Circulating Tumor Cell Detection and Outcomes with Abiraterone or Enzalutamide Treatment in Men with Metastatic Castrate-resistant Prostate Cancer.
Topics: Biomarkers, Tumor; Humans; Male; Neoplastic Cells, Circulating; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2023 |
Neuroendocrine differentiation predicts the therapeutic efficacy of abiraterone and docetaxel as first-line therapy in metastatic castration-resistant prostate cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Docetaxel; Female; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2023 |
Prostate-specific antigen response after Abiraterone treatment in mCRPC: PSA as a predictor of overall survival.
Topics: Abiraterone Acetate; Aged; Aged, 80 and over; Androgen Antagonists; Cohort Studies; Disease-Free Survival; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2023 |
Combining Poly(ADP)-Ribose Polymerase Inhibitors With Abiraterone in Castration-Resistant Prostate Cancer: Is Biomarker Testing Necessary?
Topics: Biomarkers; Humans; Male; Poly(ADP-ribose) Polymerase Inhibitors; Prostatic Neoplasms, Castration-Resistant; Ribose | 2023 |
Early On-treatment Changes in Circulating Tumor DNA Fraction and Response to Enzalutamide or Abiraterone in Metastatic Castration-Resistant Prostate Cancer.
Topics: Androgen Receptor Antagonists; Circulating Tumor DNA; Humans; Male; Nitriles; Prospective Studies; Prostatic Neoplasms, Castration-Resistant | 2023 |
Predicting response to enzalutamide and abiraterone in metastatic prostate cancer using whole-omics machine learning.
Topics: Androstenes; Biomarkers, Tumor; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2023 |
Comparison of circulating tumor DNA between African American and Caucasian patients with metastatic castrate-resistant prostate cancer post-abiraterone and/or enzalutamide.
Topics: Antineoplastic Agents; Black or African American; Circulating Tumor DNA; Humans; Male; Mutation; Nitriles; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome; White | 2023 |
Real-World Treatment Patterns Among French Patients With Metastatic Castration-Resistant Prostate Cancer Under Abiraterone or Enzalutamide.
Topics: Abiraterone Acetate; Androgen Antagonists; Humans; Male; Nitriles; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2023 |
Inhibition of Wnt/β-catenin pathway overcomes therapeutic resistance to abiraterone in castration-resistant prostate cancer.
Topics: beta Catenin; Drug Resistance, Neoplasm; Humans; Male; Neoplasm Recurrence, Local; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen | 2023 |
Frailty and survival among veterans treated with abiraterone or enzalutamide for metastatic castration-resistant prostate cancer.
Topics: Aged; Dementia; Frailty; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome; Veterans | 2023 |
Circulating Tumor DNA Biomarkers for Response Assessment in Prostate Cancer.
Topics: Biomarkers, Tumor; Circulating Tumor DNA; Humans; Male; Prostatic Neoplasms, Castration-Resistant | 2023 |
Validation of an LC-MS/MS method for simultaneous quantification of abiraterone, enzalutamide and darolutamide in human plasma.
Topics: Chromatography, Liquid; Humans; Male; Nitriles; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Tandem Mass Spectrometry | 2023 |
Mental health care utilization among men with castration-resistant prostate cancer receiving abiraterone or enzalutamide.
Topics: Androstenes; Humans; Male; Nitriles; Patient Acceptance of Health Care; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2023 |
Clinical outcomes in patients with metastatic castrate-resistant prostate cancer treated with abiraterone with or without ongoing androgen deprivation therapy: A retrospective case-control study.
Topics: Androgen Antagonists; Androstenes; Case-Control Studies; Humans; Male; Neoplasm Metastasis; Progression-Free Survival; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2023 |
A prospective, multicenter study on the clinical effectiveness of abiraterone in metastatic castration-resistant prostate cancer in Korea: Pre- vs. post-chemotherapy.
Topics: Drug-Related Side Effects and Adverse Reactions; Humans; Male; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Republic of Korea; Treatment Outcome | 2023 |
Survivin-targeted nanomedicine for increased potency of abiraterone and enzalutamide against prostate cancer.
Topics: Gold; Humans; Male; Metal Nanoparticles; Nanomedicine; Prostatic Neoplasms, Castration-Resistant; Survivin | 2023 |
A common germline variant in CYP11B1 is associated with adverse clinical outcome of treatment with abiraterone or enzalutamide.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgens; Germ Cells; Humans; Male; Membrane Proteins; Nitriles; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Steroid 11-beta-Hydroxylase; Treatment Outcome | 2023 |
Defining End Points in Phase II Trials of Metastatic Castration-Resistant Prostate Cancer. Re: Impact of Addition of Metformin to Abiraterone in Metastatic Castration-Resistant Prostate Cancer Patients With Disease Progressing While Receiving Abiraterone
Topics: Abiraterone Acetate; Androstenes; Humans; Male; Metformin; Pilot Projects; Prostatic Neoplasms, Castration-Resistant | 2019 |
Second line chemotherapy and visceral metastases are associated with poor survival in patients with mCRPC receiving
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Dipeptides; Heterocyclic Compounds, 1-Ring; Humans; Lutetium; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Radiopharmaceuticals; Taxoids | 2019 |
Bioanalytical evaluation of dried plasma spots for monitoring of abiraterone and ∆(4)-abiraterone from cancer patients.
Topics: Androstenes; Chromatography, Liquid; Dried Blood Spot Testing; Drug Monitoring; Humans; Linear Models; Male; Prostatic Neoplasms, Castration-Resistant; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2019 |
Evaluation of PSMA expression changes on PET/CT before and after initiation of novel antiandrogen drugs (enzalutamide or abiraterone) in metastatic castration-resistant prostate cancer patients.
Topics: Aged; Androstenes; Antigens, Surface; Benzamides; Gene Expression Regulation, Neoplastic; Glutamate Carboxypeptidase II; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2019 |
Managing lines of therapy in castration-resistant prostate cancer: real-life snapshot from a multicenter cohort.
Topics: Aged; Aged, 80 and over; Androstenes; Benzamides; Cohort Studies; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2020 |
Improved Androgen Receptor Splice Variant 7 Detection Using a Highly Sensitive Assay to Predict Resistance to Abiraterone or Enzalutamide in Metastatic Prostate Cancer Patients.
Topics: Androstenes; Benzamides; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen | 2021 |
Abiraterone experience in a patient with metastatic castration-resistant prostate cancer on hemodialysis.
Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Humans; Male; Prednisone; Prostatic Neoplasms, Castration-Resistant; Renal Dialysis | 2019 |
Overall and progression-free survival with cabazitaxel in metastatic castration-resistant prostate cancer in routine clinical practice: the FUJI cohort.
Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Neoplasms; Docetaxel; Humans; Kaplan-Meier Estimate; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prednisone; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Outcome | 2019 |
Chemotherapy, not androgen receptor-targeted therapy should be used upfront for metastatic hormone-sensitive prostate cancer. CON: Novel oral agents provide an attractive alternative to chemotherapy in metastatic hormone-sensitive prostate cancer.
Topics: Administration, Oral; Androstenes; Benzamides; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Thiohydantoins | 2020 |
Radiotherapy in metastatic castration resistant prostate cancer patients with oligo-progression during abiraterone-enzalutamide treatment: a mono-institutional experience.
Topics: Aged; Aged, 80 and over; Androgen Receptor Antagonists; Androstenes; Antineoplastic Agents; Benzamides; Combined Modality Therapy; Disease Progression; Disease-Free Survival; Drug Resistance, Neoplasm; Humans; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Radiosurgery; Radiotherapy, Conformal; Receptors, Androgen; Retrospective Studies; Treatment Outcome | 2019 |
Re: Wnt-pathway Activating Mutations Are Associated with Resistance to First-line Abiraterone and Enzalutamide in Castration-resistant Prostate Cancer.
Topics: Androstenes; Benzamides; Humans; Male; Mutation; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant | 2020 |
Prognostic impact of C-reactive protein-albumin ratio for the lethality in castration-resistant prostate cancer.
Topics: Aged; Albumins; Androgen Antagonists; Androstenes; Antineoplastic Agents; Benzamides; C-Reactive Protein; Docetaxel; Humans; Male; Nitriles; Phenylthiohydantoin; Predictive Value of Tests; Prognosis; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2019 |
TP53 Gain-of-Function Mutations in Circulating Tumor DNA in Men With Metastatic Castration-Resistant Prostate Cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Circulating Tumor DNA; Disease Progression; DNA Mutational Analysis; Drug Resistance, Neoplasm; Gain of Function Mutation; Humans; Liquid Biopsy; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prognosis; Prostate; Prostatic Neoplasms, Castration-Resistant; Tumor Suppressor Protein p53 | 2020 |
Propensity score-matched comparison of docetaxel and androgen receptor axis-targeted agents in patients with castration-resistant intraductal carcinoma of the prostate.
Topics: Administration, Oral; Aged; Androstenes; Antineoplastic Agents; Benzamides; Biopsy; Docetaxel; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Male; Nitriles; Phenylthiohydantoin; Propensity Score; Prostate; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Retrospective Studies; Treatment Outcome | 2020 |
A prospective observational registry evaluating clinical outcomes of Radium-223 treatment in a nonstudy population.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Benzamides; Bone Neoplasms; Chemoradiotherapy; Docetaxel; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Nitriles; Outcome Assessment, Health Care; Phenylthiohydantoin; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Radium; Registries; Taxoids | 2020 |
Real World Experience With Pembrolizumab in Recurrent or Advanced Prostate Cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Neoplasms; Combined Modality Therapy; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Radiosurgery; Retrospective Studies; Tissue Extracts | 2020 |
Circulating miR-141 and miR-375 are associated with treatment outcome in metastatic castration resistant prostate cancer.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Case-Control Studies; Circulating MicroRNA; Docetaxel; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; Middle Aged; Neoplasm Metastasis; Prognosis; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Survival Rate | 2020 |
Systemic treatment for metastatic castrate resistant prostate cancer: Does seqence matter?
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Neoplasms; Docetaxel; Drug Administration Schedule; Humans; Kallikreins; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Rate | 2020 |
Topics: Androstenes; Humans; Male; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2020 |
Adherence to abiraterone or enzalutamide in elderly metastatic castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Benzamides; Cohort Studies; Humans; Male; Medication Adherence; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2020 |
Role of the neutrophil/lymphocyte ratio in patients with metastatic castration-resistant prostate cancer treated first-line with abiraterone.
Topics: Aged; Aged, 80 and over; Androstenes; Humans; Leukocyte Count; Lymphocytes; Male; Middle Aged; Neoplasm Metastasis; Neutrophils; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2020 |
Treatment Patterns and Outcomes in Patients With Metastatic Castration-resistant Prostate Cancer in a Real-world Clinical Practice Setting in the United States.
Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Docetaxel; Follow-Up Studies; Humans; Male; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Rate; Taxoids; Tissue Extracts | 2020 |
Economic Outcomes in Patients with Chemotherapy-Naïve Metastatic Castration-Resistant Prostate Cancer Treated with Enzalutamide or Abiraterone Acetate Plus Prednisone.
Topics: Abiraterone Acetate; Adult; Aged; Androstenes; Antineoplastic Agents, Hormonal; Benzamides; Cohort Studies; Drug Administration Schedule; Health Care Costs; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prednisone; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies | 2020 |
Preliminary results of targeted prostate-specific membrane antigen imaging in evaluating the efficacy of a novel hormone agent in metastatic castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antigens, Surface; Antineoplastic Agents, Hormonal; Bone Neoplasms; Glutamate Carboxypeptidase II; Humans; Lymphatic Metastasis; Male; Middle Aged; Organotechnetium Compounds; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant; Radiopharmaceuticals; Retrospective Studies; Single Photon Emission Computed Tomography Computed Tomography; Treatment Outcome | 2020 |
Combination of statin/vitamin D and metastatic castration-resistant prostate cancer (CRPC): a post hoc analysis of two randomized clinical trials.
Topics: Androstenes; Drug Therapy, Combination; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Neoplasm Metastasis; Prednisone; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Randomized Controlled Trials as Topic; Vitamin D | 2020 |
Comprehensive analysis of serum chromogranin A and neuron-specific enolase levels in localized and castration-resistant prostate cancer.
Topics: Adenocarcinoma; Adult; Aged; Androstenes; Antineoplastic Agents; Benzamides; Chromogranin A; Docetaxel; Humans; Male; Middle Aged; Neoplasm Staging; Nitriles; Phenylthiohydantoin; Phosphopyruvate Hydratase; Prognosis; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms, Castration-Resistant; Proton Pump Inhibitors; Survival Rate | 2021 |
Use of record linkage to evaluate treatment outcomes and trial eligibility in a real-world metastatic prostate cancer population in Scotland.
Topics: Adult; Aged; Aged, 80 and over; Androgen Antagonists; Androstenes; Benzamides; Clinical Decision-Making; Clinical Trials as Topic; Electronic Health Records; Eligibility Determination; Humans; Male; Medical Record Linkage; Middle Aged; Neoplasm Metastasis; Nitriles; Patient Selection; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Scotland; State Medicine; Time Factors; Treatment Outcome | 2020 |
Treatment with abiraterone and enzalutamide does not overcome poor outcome from metastatic castration-resistant prostate cancer in men with the germline homozygous HSD3B1 c.1245C genotype.
Topics: Abiraterone Acetate; Androgen Antagonists; Androstenes; Benzamides; Genotype; Germ Cells; Humans; Male; Multienzyme Complexes; Nitriles; Phenylthiohydantoin; Progesterone Reductase; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Steroid Isomerases; Treatment Outcome | 2020 |
Concurrent or layered treatment with radium-223 and enzalutamide or abiraterone/prednisone: real-world clinical outcomes in patients with metastatic castration-resistant prostate cancer.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Density Conservation Agents; Bone Neoplasms; Chemoradiotherapy; Clinical Trials, Phase III as Topic; Denosumab; Humans; Male; Middle Aged; Multicenter Studies as Topic; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prednisone; Prostatic Neoplasms, Castration-Resistant; Radium; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Rate; Treatment Outcome; Zoledronic Acid | 2020 |
Blood platelet volume predicts treatment-specific outcomes of metastatic castration-resistant prostate cancer.
Topics: Aged; Androstenes; Benzamides; Biomarkers, Tumor; Docetaxel; Erythrocytes; Humans; Male; Mean Platelet Volume; Nitriles; Phenylthiohydantoin; Platelet Count; Prognosis; Proportional Hazards Models; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Retrospective Studies; Treatment Outcome | 2020 |
Homozygous HSD3B1(1245C) inheritance and poor outcomes in metastatic castration-resistant prostate cancer with abiraterone or enzalutamide: what does it mean?
Topics: Androstenes; Benzamides; Germ Cells; Humans; Male; Multienzyme Complexes; Nitriles; Phenylthiohydantoin; Prospective Studies; Prostatic Neoplasms, Castration-Resistant | 2020 |
Identifying Prostate Surface Antigen Patterns of Change in Patients with Metastatic Hormone Sensitive Prostate Cancer Treated with Abiraterone and Prednisone.
Topics: Aged; Androstenes; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Humans; Male; Prednisone; Prostatic Neoplasms, Castration-Resistant; Survival Analysis; Treatment Outcome | 2020 |
Plasma tumour DNA as an early indicator of treatment response in metastatic castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; DNA, Neoplasm; Humans; Male; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant | 2020 |
Circulating-tumor DNA as predictor of enzalutamide response post-abiraterone treatment in metastatic castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomarkers, Tumor; Circulating Tumor DNA; Disease-Free Survival; Drug Resistance, Neoplasm; Follow-Up Studies; Gene Amplification; Humans; Kallikreins; Male; Middle Aged; Mutation; Neoplasm Grading; Nitriles; Phenylthiohydantoin; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies | 2020 |
AR-V7 as a Biomarker for Resistance to Treatment with Abiraterone/Enzalutamide in Three Latin American Countries: A Hypothetical Cost-Saving Analysis.
Topics: Androstenes; Benzamides; Biomarkers; Colombia; Drug Resistance, Neoplasm; Humans; Latin America; Male; Mexico; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen | 2020 |
Adding carboplatin to chemotherapy regimens for metastatic castrate-resistant prostate cancer in postsecond generation hormone therapy setting: Impact on treatment response and survival outcomes.
Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Carboplatin; Disease Progression; Docetaxel; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Rate; Taxoids; Treatment Failure | 2020 |
Challenges of Treating a Patient With Advanced Prostate Cancer During the COVID-19 Pandemic.
Topics: Aged; Androgen Antagonists; Androstenes; Anticoagulants; Antineoplastic Agents; Betacoronavirus; Bone Density Conservation Agents; Bone Neoplasms; Cancer Pain; Coronavirus Infections; COVID-19; Disease Progression; Docetaxel; Drug Combinations; Eligibility Determination; Heparin, Low-Molecular-Weight; Humans; Intensive Care Units; Lopinavir; Male; Oxygen Inhalation Therapy; Palliative Care; Pandemics; Pneumonia, Viral; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency; Respiratory Insufficiency; Reverse Transcriptase Polymerase Chain Reaction; Ritonavir; SARS-CoV-2; Severity of Illness Index; Zoledronic Acid | 2020 |
YB-1 variant and androgen receptor axis-targeted agents in metastatic castration-resistant prostate cancer patients.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Cohort Studies; Disease Progression; Disease-Free Survival; Drug Resistance, Neoplasm; Genotype; Humans; Male; Middle Aged; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Y-Box-Binding Protein 1 | 2020 |
Development of 5D3-DM1: A Novel Anti-Prostate-Specific Membrane Antigen Antibody-Drug Conjugate for PSMA-Positive Prostate Cancer Therapy.
Topics: Androgen Antagonists; Androstenes; Animals; Antibodies, Monoclonal; Antigens, Surface; Benzamides; Cell Line, Tumor; Centrosome; Glutamate Carboxypeptidase II; Humans; Immunoconjugates; Male; Mice; Mice, Nude; Nitriles; PC-3 Cells; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Tubulin Modulators; Xenograft Model Antitumor Assays | 2020 |
PROACTA: a survey on the actual attitude of the Italian radiation oncologists in the management and prescription of hormonal therapy in prostate cancer patients.
Topics: Androgen Antagonists; Androstenes; Antineoplastic Agents, Hormonal; Attitude of Health Personnel; Benzamides; Combined Modality Therapy; Gonadotropin-Releasing Hormone; Health Care Surveys; Humans; Italy; Male; Nitriles; Phenylthiohydantoin; Prostatectomy; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Radiation Oncologists; Risk Factors; Salvage Therapy | 2021 |
The clinical benefit of sequential therapy with androgen receptor axis-targeted agents alone in patients with castration-resistant prostate cancer: A propensity score-matched comparison study.
Topics: Aged; Aged, 80 and over; Androgen Receptor Antagonists; Androstenes; Antineoplastic Agents, Hormonal; Benzamides; Disease Progression; Drug Therapy, Combination; Humans; Male; Nitriles; Phenylthiohydantoin; Progression-Free Survival; Propensity Score; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Rate; Treatment Outcome | 2020 |
Steroid Sulfatase Stimulates Intracrine Androgen Synthesis and is a Therapeutic Target for Advanced Prostate Cancer.
Topics: Androgen Antagonists; Androgens; Androstenes; Benzamides; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Male; Neoplasm Staging; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; RNA-Seq; Steryl-Sulfatase | 2020 |
Impact of antiandrogen withdrawal syndrome in castration-resistant prostate cancer patients treated with abiraterone or enzalutamide.
Topics: Androgen Antagonists; Androstenes; Benzamides; Humans; Male; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2020 |
Overall Survival Among Chemotherapy-Naive Patients With Castration-Resistant Prostate Cancer Under Abiraterone Versus Enzalutamide: A Direct Comparison Based on a 2014-2018 French Population Study (the SPEAR Cohort).
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Benzamides; Comorbidity; Humans; Male; Nitriles; Phenylthiohydantoin; Proportional Hazards Models; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Survival Analysis | 2021 |
Blood-based gene expression signature associated with metastatic castrate-resistant prostate cancer patient response to abiraterone plus prednisone or enzalutamide.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Androstenes; Benzamides; Biomarkers, Tumor; Bone Neoplasms; Follow-Up Studies; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplastic Cells, Circulating; Nitriles; Phenylthiohydantoin; Prednisone; Prognosis; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Rate; Transcriptome | 2021 |
The prognostic value of serum MMP-7 levels in prostate cancer patients who received docetaxel, abiraterone, or enzalutamide therapy.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Benzamides; Docetaxel; Humans; Male; Matrix Metalloproteinase 7; Middle Aged; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Rate | 2021 |
Androgen receptor signaling-targeted therapy and taxane chemotherapy induce visceral metastasis in castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Benzamides; Docetaxel; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Retrospective Studies; Risk Factors; Signal Transduction; Taxoids | 2021 |
Prognostic significance of complete blood count parameters in castration-resistant prostate cancer patients treated with androgen receptor pathway inhibitors.
Topics: Aged; Aged, 80 and over; Androgen Receptor Antagonists; Androstenes; Benzamides; Blood Cell Count; Humans; Male; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Rate | 2021 |
Influence of abiraterone and enzalutamide on body composition in patients with metastatic castration resistant prostate cancer.
Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Body Composition; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant | 2020 |
Observational study on time on treatment with abiraterone and enzalutamide.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Androstenes; Benzamides; Chemotherapy, Adjuvant; Drug Prescriptions; Humans; Kaplan-Meier Estimate; Male; Medication Adherence; Middle Aged; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Randomized Controlled Trials as Topic; Registries; Sweden; Time Factors; Treatment Outcome | 2020 |
Cytoreductive radiotherapy combined with abiraterone in metastatic castration-resistance prostate cancer: a single center experience.
Topics: Aged; Aged, 80 and over; Androstenes; Combined Modality Therapy; Cytoreduction Surgical Procedures; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant | 2021 |
Cost-effectiveness analysis of cabazitaxel for metastatic castration resistant prostate cancer after docetaxel and androgen-signaling-targeted inhibitor resistance.
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Cost-Benefit Analysis; Docetaxel; Drug Resistance, Neoplasm; Follow-Up Studies; Humans; Male; Prognosis; Prostatic Neoplasms, Castration-Resistant; Quality-Adjusted Life Years; Survival Rate; Taxoids | 2021 |
Ferroptosis Inducers Are a Novel Therapeutic Approach for Advanced Prostate Cancer.
Topics: Amino Acid Transport System y+; Androgen Antagonists; Androstenes; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Carbolines; Cell Line, Tumor; Drug Resistance, Neoplasm; Ferroptosis; Fusion Regulatory Protein 1, Heavy Chain; Humans; Male; Mice; Neoplasm Staging; Nitriles; Phenylthiohydantoin; Phospholipid Hydroperoxide Glutathione Peroxidase; Piperazines; Prostate; Prostatic Neoplasms, Castration-Resistant; Xenograft Model Antitumor Assays | 2021 |
Androgen receptor gain in circulating free DNA and splicing variant 7 in exosomes predict clinical outcome in CRPC patients treated with abiraterone and enzalutamide.
Topics: Aged; Aged, 80 and over; Alternative Splicing; Androstenes; Benzamides; Biomarkers, Tumor; Cell-Free Nucleic Acids; Drug Resistance, Neoplasm; Exosomes; Follow-Up Studies; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Retrospective Studies; Survival Rate | 2021 |
Prognostic impact of prior local therapy in castration-resistant prostate cancer.
Topics: Aged; Androstenes; Antineoplastic Agents; Benzamides; Docetaxel; Humans; Male; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Survival Analysis | 2021 |
SEOM clinical guidelines for the treatment of advanced prostate cancer (2020).
Topics: Androgen Antagonists; Androstenes; Antineoplastic Agents; Benzamides; Combined Modality Therapy; Docetaxel; Genes, BRCA1; Genes, BRCA2; Genetic Testing; Humans; Male; Medical Oncology; Nitriles; Orchiectomy; Phenylthiohydantoin; Phthalazines; Piperazines; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Radiotherapy; Randomized Controlled Trials as Topic; Societies, Medical; Spain; Thiohydantoins | 2021 |
Efficacy and tolerability of current treatments for hormone-refractory prostate cancer patients with visceral metastases.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Benzamides; Docetaxel; Drug Administration Schedule; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies | 2021 |
The association between missense polymorphisms in SRD5A2 and HSD3B1 and treatment failure with abiraterone for castration-resistant prostate cancer.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aged; Aged, 80 and over; Alleles; Androstenes; Genetic Association Studies; Genotype; Humans; Male; Membrane Proteins; Middle Aged; Multienzyme Complexes; Polymorphism, Genetic; Progesterone Reductase; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Steroid Isomerases; Treatment Failure | 2021 |
Safety of concomitant therapy with radium-223 and abiraterone or enzalutamide in a real-world population.
Topics: Aged; Androstenes; Benzamides; Bone Neoplasms; Combined Modality Therapy; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Radium; Survival Rate; Veterans | 2021 |
Cabazitaxel versus abiraterone or enzalutamide in metastatic castration-resistant prostate cancer: post hoc analysis of the CARD study excluding chemohormonal therapy for castrate-naive disease.
Topics: Aged; Androstenes; Benzamides; Disease-Free Survival; Humans; Male; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Outcome | 2021 |
The effects of new life-prolonging drugs for metastatic castration-resistant prostate cancer (mCRPC) patients in a real-world population.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Chemoradiotherapy; Docetaxel; Follow-Up Studies; Humans; Male; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Radium; Retrospective Studies; Survival Rate; Taxoids | 2021 |
Treatment and Patient Selection for Patients with Metastatic Castration-resistant Prostate After Progression on Docetaxel and Abiraterone/Enzalutamide: When to Play Your CARD and When to Do Your PARP.
Topics: Androstenes; Benzamides; Docetaxel; Humans; Male; Nitriles; Orchiectomy; Patient Selection; Pharmaceutical Preparations; Phenylthiohydantoin; Poly(ADP-ribose) Polymerase Inhibitors; Prostate; Prostatic Neoplasms, Castration-Resistant | 2021 |
Prognostic role of platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio in patients with metastatic castration resistant prostate cancer treated with abiraterone or enzalutamide.
Topics: Androstenes; Benzamides; Humans; Lymphocytes; Male; Neutrophils; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies | 2021 |
Circulating Tumor Cell Chromosomal Instability and Neuroendocrine Phenotype by Immunomorphology and Poor Outcomes in Men with mCRPC Treated with Abiraterone or Enzalutamide.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Benzamides; Chromosomal Instability; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplastic Cells, Circulating; Neurosecretory Systems; Nitriles; Phenotype; Phenylthiohydantoin; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2021 |
Development and validation of circulating tumour cell enumeration (Epic Sciences) as a prognostic biomarker in men with metastatic castration-resistant prostate cancer.
Topics: Adult; Aged; Aged, 80 and over; Androgen Antagonists; Androstenes; Benzamides; Biomarkers, Tumor; Cell Count; Clinical Decision-Making; Humans; Keratins; Leukocyte Common Antigens; Male; Middle Aged; Neoplasm Metastasis; Neoplastic Cells, Circulating; Nitriles; Phenylthiohydantoin; Predictive Value of Tests; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant; Reproducibility of Results | 2021 |
Stereotactic body radiotherapy for oligoprogressive lesions in metastatic castration-resistant prostate cancer patients during abiraterone/enzalutamide treatment.
Topics: Androstenes; Antineoplastic Agents; Benzamides; Combined Modality Therapy; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Nitriles; Phenylthiohydantoin; Prognosis; Progression-Free Survival; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Radiosurgery; Treatment Outcome | 2021 |
Outcomes of treatment choices in poor prognosis prostate cancer: not against all odds.
Topics: Androstenes; Benzamides; Humans; Male; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Outcome | 2021 |
Topics: Androstenes; Hormones; Humans; Male; Prostatic Neoplasms, Castration-Resistant | 2021 |
Evolution of Castration-Resistant Prostate Cancer in ctDNA during Sequential Androgen Receptor Pathway Inhibition.
Topics: Androgen Receptor Antagonists; Androstenes; Benzamides; Circulating Tumor DNA; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant | 2021 |
Effectiveness of first-line abiraterone versus enzalutamide among patients ≥80 years of age with metastatic castration-resistant prostate cancer: A retrospective propensity score-weighted comparative cohort study.
Topics: Age Factors; Aged, 80 and over; Androstenes; Benzamides; Dose-Response Relationship, Drug; Humans; Kallikreins; Male; Nitriles; Phenylthiohydantoin; Progression-Free Survival; Propensity Score; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Time Factors | 2021 |
Association of Chemotherapy, Enzalutamide, Abiraterone, and Radium 223 With Cognitive Function in Older Men With Metastatic Castration-Resistant Prostate Cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Benzamides; Cognition; Drug Therapy; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Radioisotopes; Radium | 2021 |
Hospitalization for adverse events under abiraterone or enzalutamide exposure in real-world setting: A French population-based study on prostate cancer patients.
Topics: Acute Kidney Injury; Androstenes; Atrial Fibrillation; Benzamides; Brain Ischemia; Hospitalization; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Stroke; Treatment Outcome | 2022 |
Exosomal TUBB3 mRNA expression of metastatic castration-resistant prostate cancer patients: Association with patient outcome under abiraterone.
Topics: Aged; Androstenes; Biomarkers, Tumor; Drug Resistance, Neoplasm; Exosomes; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; Male; Progression-Free Survival; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Risk Assessment; RNA, Messenger; Tubulin | 2021 |
Real-world incidence of symptomatic skeletal events and bone-modifying agent use in castration-resistant prostate cancer - an Australian multi-centre observational study.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Australia; Benzamides; Bone Density Conservation Agents; Bone Neoplasms; Denosumab; Docetaxel; Humans; Incidence; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Spinal Cord Compression; Treatment Outcome; Zoledronic Acid | 2021 |
Prognostic Score and Benefit from Abiraterone in First-line Metastatic, Castration-resistant Prostate Cancer.
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Humans; Male; Middle Aged; Prognosis; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2021 |
Beyond Frontline Therapy with Abiraterone and Enzalutamide in Metastatic Castration-Resistant Prostate Cancer: A Real-World US Study.
Topics: Abiraterone Acetate; Adult; Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2021 |
KAT2A-mediated AR translocation into nucleus promotes abiraterone-resistance in castration-resistant prostate cancer.
Topics: Acetylation; Androstenes; Animals; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Acetyltransferases; Humans; Lysine; Male; Mice, Nude; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Protein Transport; Receptors, Androgen; RNA, Messenger; Up-Regulation | 2021 |
The heterogeneity of intraductal carcinoma of the prostate is associated with different efficacy of standard first-line therapy for patients with metastatic castration-resistant prostate cancer.
Topics: Aged; Androstenes; Antineoplastic Agents; Disease-Free Survival; Docetaxel; Humans; Male; Middle Aged; Progression-Free Survival; Prostate; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Rate; Treatment Outcome | 2021 |
The effect of chemotherapy on the exposure-response relation of abiraterone in metastatic castration-resistant prostate cancer.
Topics: Abiraterone Acetate; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Humans; Male; Prednisone; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2022 |
Docetaxel chemotherapy in metastatic castration-resistant prostate cancer: cost of care in Medicare and commercial populations.
Topics: Aged; Androstenes; Benzamides; Docetaxel; Drug Costs; Health Care Costs; Humans; Male; Medicare; Middle Aged; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Radium; Taxoids; United States | 2017 |
Potential drug-drug interactions with abiraterone in metastatic castration-resistant prostate cancer patients: a prevalence study in France.
Topics: Aged; Aged, 80 and over; Androstenes; Comorbidity; Cross-Sectional Studies; Disease-Free Survival; Drug Interactions; Electronic Health Records; Enzyme Inhibitors; France; Humans; Male; Neoplasm Metastasis; Pain; Pharmacists; Polypharmacy; Prevalence; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies | 2017 |
Clinical Significance of Androgen Receptor Splice Variant-7 mRNA Detection in Circulating Tumor Cells of Men With Metastatic Castration-Resistant Prostate Cancer Treated With First- and Second-Line Abiraterone and Enzalutamide.
Topics: Aged; Androstenes; Antineoplastic Agents; Benzamides; Cohort Studies; Disease-Free Survival; Humans; Kallikreins; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen; RNA, Messenger; Treatment Outcome | 2017 |
First-line management of metastatic castrate-resistant prostate cancer patients: Audit of real-life practices.
Topics: Age Factors; Aged; Androgen Antagonists; Androstenes; Antineoplastic Agents; Benzamides; Bone and Bones; Docetaxel; Humans; Male; Medical Audit; Medical Oncology; Neoplasm Grading; Nitriles; Phenylthiohydantoin; Practice Patterns, Physicians'; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Radiation Oncology; Radionuclide Imaging; Regression Analysis; Surveys and Questionnaires; Taxoids; Tumor Burden; Urology | 2017 |
Association Between Androgen Receptor Splice Variants and Prostate Cancer Resistance to Abiraterone and Enzalutamide.
Topics: Androstenes; Benzamides; Humans; Male; Neoplastic Cells, Circulating; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; RNA, Messenger | 2017 |
Identification of risk factors predicting febrile neutropenia in patients with metastatic germ cell tumors receiving cisplatin-based combination chemotherapy.
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Baltimore; Benzamides; Cisplatin; Febrile Neutropenia; Humans; Ifosfamide; Male; Neoplasms, Germ Cell and Embryonal; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Risk Factors | 2017 |
Long-term clinical impact of PSA surge in castration-resistant prostate cancer patients treated with abiraterone.
Topics: Aged; Androstenes; Antineoplastic Agents; Disease-Free Survival; Drug Monitoring; Humans; Italy; Male; Medication Therapy Management; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Time | 2017 |
Exploring the optimal sequence of abiraterone and enzalutamide in patients with chemotherapy-naïve castration-resistant prostate cancer: The Kyoto-Baltimore collaboration.
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Baltimore; Benzamides; Disease Progression; Drug Administration Schedule; Humans; International Cooperation; Japan; Kallikreins; Male; Neoplasm Grading; Nitriles; Phenylthiohydantoin; Progression-Free Survival; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Analysis; Time Factors | 2017 |
Editorial Comment to Identification of risk factors predicting febrile neutropenia in patients with metastatic germ cell tumors receiving cisplatin-based combination chemotherapy.
Topics: Androstenes; Baltimore; Benzamides; Cisplatin; Drug Therapy, Combination; Febrile Neutropenia; Humans; Male; Neoplasms, Germ Cell and Embryonal; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Risk Factors | 2017 |
Editorial Comment to Exploring the optimal sequence of abiraterone and enzalutamide in patients with chemotherapy-naïve castration-resistant prostate cancer: The Kyoto-Baltimore collaboration.
Topics: Androstenes; Baltimore; Benzamides; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant | 2017 |
Lactate dehydrogenase predicts combined progression-free survival after sequential therapy with abiraterone and enzalutamide for patients with castration-resistant prostate cancer.
Topics: Aged; Androstenes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Disease Progression; Disease-Free Survival; Drug Monitoring; Drug Resistance, Neoplasm; Humans; Japan; L-Lactate Dehydrogenase; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Predictive Value of Tests; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies | 2017 |
Early National Dissemination of Abiraterone and Enzalutamide for Advanced Prostate Cancer in Medicare Part D.
Topics: Aged; Androstenes; Antineoplastic Agents; Benzamides; Catchment Area, Health; Drug Prescriptions; Humans; Insurance Coverage; Male; Medical Oncology; Medicare Part D; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Practice Patterns, Physicians'; Prostatic Neoplasms, Castration-Resistant; United States; Urology | 2017 |
Combining Abiraterone and Radiotherapy in Prostate Cancer Patients Who Progressed During Abiraterone Therapy.
Topics: Aged; Aged, 80 and over; Androstenes; Combined Modality Therapy; Cytochrome P-450 Enzyme Inhibitors; Humans; Male; Middle Aged; Prostatic Neoplasms, Castration-Resistant; Survival Analysis | 2017 |
Re: Emmanuel S. Antonarakis, Changxue Lu, Brandon Luber, et al. Clinical Significance of Androgen Receptor Splice Variant-7 mRNA Detection in Circulating Tumor Cells of Men with Metastatic Castration-resistant Prostate Cancer Treated with First- and Secon
Topics: Androstenes; Benzamides; Drug Resistance, Neoplasm; Humans; Male; Neoplastic Cells, Circulating; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; RNA, Messenger | 2017 |
Reply to Julie Steinestel, Christof Bernemann, Andres J. Schrader, and Jochen K. Lennerz's Letter to the Editor re: Emmanuel S. Antonarakis, Changxue Lu, Brandon Luber, et al. Clinical Significance of Androgen Receptor Splice Variant-7 mRNA Detection in C
Topics: Androstenes; Benzamides; Drug Resistance, Neoplasm; Humans; Male; Neoplastic Cells, Circulating; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; RNA, Messenger | 2017 |
Prognostic nutritional index predicts initial response to treatment and prognosis in metastatic castration-resistant prostate cancer patients treated with abiraterone.
Topics: Aged; Androstenes; Antineoplastic Agents; Cohort Studies; Follow-Up Studies; Humans; Male; Nutrition Assessment; Prognosis; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2017 |
Interrogating Metastatic Prostate Cancer Treatment Switch Decisions: A Multi-institutional Survey.
Topics: Androstenes; Biomarkers, Tumor; Clinical Decision-Making; Disease Progression; Docetaxel; Humans; Male; Neoplasm Metastasis; Neoplastic Cells, Circulating; Practice Patterns, Physicians'; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Surveys and Questionnaires; Taxoids; Treatment Outcome; Tubulin Modulators | 2018 |
Patient characteristics and overall survival in patients with post-docetaxel metastatic castration-resistant prostate cancer in the community setting.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Benzamides; Docetaxel; Humans; Longitudinal Studies; Male; Middle Aged; Molecular Targeted Therapy; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Retrospective Studies; Taxoids; Treatment Outcome | 2017 |
Commentary on: Abiraterone Plus Prednisolone in Metastatic, Castration-sensitive Prostate Cancer.
Topics: Abiraterone Acetate; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Castration; Disease-Free Survival; Humans; Male; Neoplasm Metastasis; Prednisolone; Prednisone; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2017 |
AR-V7 in Peripheral Whole Blood of Patients with Castration-resistant Prostate Cancer: Association with Treatment-specific Outcome Under Abiraterone and Enzalutamide.
Topics: Aged; Androstenes; Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Disease-Free Survival; Drug Resistance, Neoplasm; Humans; Kallikreins; Liquid Biopsy; Logistic Models; Male; Multivariate Analysis; Neoplastic Cells, Circulating; Nitriles; Odds Ratio; Phenylthiohydantoin; Polymerase Chain Reaction; Predictive Value of Tests; Proportional Hazards Models; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen; Reproducibility of Results; Retrospective Studies; Risk Factors; RNA, Messenger; Time Factors; Treatment Outcome | 2017 |
Treatment with abiraterone in metastatic castration-resistant prostate cancer patients progressing after docetaxel: a retrospective study.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Humans; Kallikreins; Male; Middle Aged; Neoplasm Metastasis; Prednisone; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Taxoids | 2017 |
Abiraterone Followed by Enzalutamide Versus Enzalutamide Followed by Abiraterone in Chemotherapy-naive Patients With Metastatic Castration-resistant Prostate Cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Benzamides; Disease-Free Survival; Drug Administration Schedule; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2018 |
AR-V7 predicting treatment response in metastasized prostate cancer: has it peaked?
Topics: Androgen Receptor Antagonists; Androstadienes; Androstenes; Antineoplastic Agents; Benzamides; Benzimidazoles; Clinical Trials, Phase III as Topic; Humans; Male; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Randomized Controlled Trials as Topic; Receptors, Androgen; RNA Splice Sites; RNA, Messenger; Treatment Outcome | 2018 |
Abiraterone or Docetaxel Plus Androgen Deprivation in Hormone-Sensitive Prostate Cancer: More Questions Than Answers.
Topics: Abiraterone Acetate; Androgen Antagonists; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Humans; Male; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2018 |
Circulating androgen receptor combined with 18F-fluorocholine PET/CT metabolic activity and outcome to androgen receptor signalling-directed therapies in castration-resistant prostate cancer.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomarkers, Tumor; Chlorine; Choline; Docetaxel; Gene Dosage; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Signal Transduction | 2017 |
Prostate cancers that 'Wnt' respond to abiraterone.
Topics: Abiraterone Acetate; Androstenes; Cell Cycle; Cell Proliferation; Genome-Wide Association Study; Humans; Male; Prednisone; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Wnt Signaling Pathway | 2018 |
Systemic immune-inflammation index predicts the combined clinical outcome after sequential therapy with abiraterone and docetaxel for metastatic castration-resistant prostate cancer patients.
Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Docetaxel; Humans; Male; Middle Aged; Prednisone; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Severity of Illness Index; Survival Analysis; Systemic Inflammatory Response Syndrome; Treatment Outcome | 2018 |
p53 status in the primary tumor predicts efficacy of subsequent abiraterone and enzalutamide in castration-resistant prostate cancer.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Benzamides; Biomarkers, Tumor; Follow-Up Studies; Humans; Male; Middle Aged; Mutation; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; PTEN Phosphohydrolase; Retrospective Studies; Survival Rate; Tumor Suppressor Protein p53 | 2018 |
Androgen receptor splice variants bind to constitutively open chromatin and promote abiraterone-resistant growth of prostate cancer.
Topics: Androstenes; Animals; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Chromatin; Disease Progression; Drug Resistance, Neoplasm; Epigenesis, Genetic; Genomics; Humans; Male; Mice, SCID; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; rap GTP-Binding Proteins; Receptors, Androgen; RNA Splicing | 2018 |
Comparing sequencing of abiraterone and enzalutamide in men with metastatic castration-resistant prostate cancer: A retrospective study.
Topics: Androstenes; Benzamides; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies | 2018 |
Prognostic and Therapeutic Implications of Circulating Androgen Receptor Gene Copy Number in Prostate Cancer Patients Using Droplet Digital Polymerase Chain Reaction.
Topics: Aged; Androstenes; Benzamides; Bridged-Ring Compounds; Disease Progression; Disease-Free Survival; DNA, Neoplasm; Gene Dosage; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Polymerase Chain Reaction; Prognosis; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Retrospective Studies; Taxoids | 2018 |
Nationwide population-based study on the use of novel antiandrogens in men with prostate cancer in Sweden.
Topics: Age Factors; Aged; Aged, 80 and over; Androgen Antagonists; Androstenes; Antineoplastic Agents; Benzamides; Cross-Sectional Studies; Drug Prescriptions; Educational Status; Humans; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Registries; Residence Characteristics; Sweden; Time Factors | 2018 |
Taxane chemotherapy vs antiandrogen agents as first-line therapy for metastatic castration-resistant prostate cancer.
Topics: Adult; Aged; Androgen Antagonists; Androstenes; Antineoplastic Agents; Benzamides; Docetaxel; Drug Resistance, Neoplasm; Drug Substitution; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Propensity Score; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2018 |
Association among metabolic syndrome, inflammation, and survival in prostate cancer.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Benzamides; Follow-Up Studies; Humans; Inflammation; Male; Metabolic Syndrome; Middle Aged; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Risk Factors; Survival Rate | 2018 |
Circulating tumor cells and survival in abiraterone- and enzalutamide-treated patients with castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Humans; Male; Middle Aged; Neoplastic Cells, Circulating; Nitriles; Phenylthiohydantoin; Prognosis; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2018 |
Re: Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.
Topics: Abiraterone Acetate; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Humans; Male; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant | 2018 |
Nuclear Receptor LRH-1 Functions to Promote Castration-Resistant Growth of Prostate Cancer via Its Promotion of Intratumoral Androgen Biosynthesis.
Topics: Androgens; Androstenes; Animals; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Neoplasm Grading; Prostate; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Receptors, Cytoplasmic and Nuclear; Steroid 17-alpha-Hydroxylase; Xenograft Model Antitumor Assays | 2018 |
Germline DNA-repair Gene Mutations and Outcomes in Men with Metastatic Castration-resistant Prostate Cancer Receiving First-line Abiraterone and Enzalutamide.
Topics: Aged; Androgen Antagonists; Androstenes; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Ataxia Telangiectasia Mutated Proteins; Benzamides; Biomarkers, Tumor; BRCA1 Protein; BRCA2 Protein; Clinical Decision-Making; DNA Mutational Analysis; DNA Repair Enzymes; Genetic Predisposition to Disease; Germ-Line Mutation; GPI-Linked Proteins; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Proteins; Nitriles; Phenotype; Phenylthiohydantoin; Precision Medicine; Progression-Free Survival; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Time Factors; Treatment Outcome | 2018 |
Prostate cancer: AR-Vs not predictive in mCRPC.
Topics: Androstenes; Benzamides; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant | 2018 |
Abiraterone is effective and should be considered for the treatment of metastatic castrate-naïve prostate cancer.
Topics: Abiraterone Acetate; Androstenes; Anti-Inflammatory Agents; Docetaxel; Drug Therapy, Combination; Humans; Male; Neoplasm Metastasis; Prednisone; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2018 |
Quantitation of the anticancer drug abiraterone and its metabolite Δ(4)-abiraterone in human plasma using high-resolution mass spectrometry.
Topics: Androgen Receptor Antagonists; Androstenes; Antineoplastic Agents; Biological Variation, Population; Chromatography, High Pressure Liquid; Humans; Male; Prodrugs; Prostatic Neoplasms, Castration-Resistant; Sensitivity and Specificity; Steroid 17-alpha-Hydroxylase; Tandem Mass Spectrometry | 2018 |
Genomic alterations in plasma DNA from patients with metastasized prostate cancer receiving abiraterone or enzalutamide.
Topics: Androgen Receptor Antagonists; Androstenes; Benzamides; Biomarkers, Tumor; Bone Neoplasms; DNA Copy Number Variations; DNA, Neoplasm; Drug Resistance, Neoplasm; Follow-Up Studies; Genomics; Humans; Longitudinal Studies; Male; Nitriles; Phenylthiohydantoin; Prognosis; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen | 2018 |
Low-Fat Abiraterone Food Effect Is of Little Consequence.
Topics: Abiraterone Acetate; Androstenes; Humans; Male; Prospective Studies; Prostatic Neoplasms, Castration-Resistant | 2018 |
Plasma DNA and Metastatic Castration-Resistant Prostate Cancer: The Odyssey to a Clinical Biomarker Test.
Topics: Androstenes; Benzamides; Circulating Tumor DNA; DNA; Genomics; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant | 2018 |
Indirect treatment comparison of cabazitaxel for patients with metastatic castrate-resistant prostate cancer who have been previously treated with a docetaxel-containing regimen.
Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Clinical Trials as Topic; Docetaxel; Humans; Male; Meta-Analysis as Topic; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Salvage Therapy; Survival Rate; Taxoids | 2018 |
Response to flutamide, as second-line therapy after bicalutamide, predicts efficacy of abiraterone, not that of enzalutamide.
Topics: Aged; Aged, 80 and over; Androstenes; Anilides; Antineoplastic Agents; Benzamides; Disease-Free Survival; Flutamide; Humans; Male; Middle Aged; Nitriles; Outcome Assessment, Health Care; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Tosyl Compounds | 2018 |
Abiraterone plus olaparib in prostate cancer: a new form of synthetic lethality?
Topics: Androstenes; Double-Blind Method; Humans; Male; Phthalazines; Piperazines; Prostatic Neoplasms, Castration-Resistant; Synthetic Lethal Mutations | 2018 |
Real world evidence: Abiraterone use post-docetaxel in metastatic castrate-resistant prostate cancer.
Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Disease Progression; Docetaxel; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Rate | 2019 |
Abiraterone-Olaparib Combo Aids Men with mCRPC.
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Double-Blind Method; Humans; Male; Phthalazines; Piperazines; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2018 |
Radium-223 (Xofigo) with concurrent abiraterone or enzalutamide: predictive biomarkers of improved overall survival in a clinically advanced cohort.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomarkers, Tumor; Chemoradiotherapy; Follow-Up Studies; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Radium; Retrospective Studies; Survival Rate | 2019 |
Therapeutic Discovery for Castration Resistant Prostate Cancer: Patient-derived Xenograft Modelling Brings New Options to the Table.
Topics: Androstenes; Benzamides; Heterografts; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Ribosomes | 2018 |
Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy.
Topics: Androstenes; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azepines; Benzamides; Benzothiazoles; Drug Resistance, Neoplasm; Humans; Indoles; Male; Mice, Inbred NOD; Mice, SCID; Molecular Targeted Therapy; Naphthyridines; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-pim-1; Ribosomes; RNA Polymerase I; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays | 2018 |
Improving outcome in patients with prostate and kidney cancer: heading in the right direction?
Topics: Androstenes; Antineoplastic Agents; Clinical Decision-Making; Humans; Immunotherapy; Kidney Neoplasms; Male; Neoplasm Metastasis; Patient Participation; Poly(ADP-ribose) Polymerase Inhibitors; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Protein-Tyrosine Kinases | 2018 |
Switch from abiraterone plus prednisone to abiraterone plus dexamethasone at asymptomatic PSA progression in patients with metastatic castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Asymptomatic Diseases; Dexamethasone; Disease Progression; Drug Substitution; Humans; Male; Middle Aged; Neoplasm Metastasis; Prednisone; Prognosis; Progression-Free Survival; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies | 2019 |
Docetaxel-rechallenge in castration-resistant prostate cancer: defining clinical factors for successful treatment response and improvement in overall survival.
Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Disease-Free Survival; Docetaxel; Follow-Up Studies; Gonadotropin-Releasing Hormone; Humans; Lymphatic Metastasis; Male; Middle Aged; Mitoxantrone; Neoplasm Grading; Orchiectomy; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms, Castration-Resistant; Retreatment; Retrospective Studies; Survival Rate; Taxoids | 2018 |
Epigenetic Reprogramming with Antisense Oligonucleotides Enhances the Effectiveness of Androgen Receptor Inhibition in Castration-Resistant Prostate Cancer.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androstenes; Animals; Benzamides; Cell Line, Tumor; Cell Proliferation; Disease Progression; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Humans; Male; Mice; Mice, SCID; Neoplasm Recurrence, Local; Neoplasm Transplantation; Nitriles; Oligonucleotides, Antisense; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Signal Transduction | 2018 |
Cancer therapeutics-related cardiac dysfunction in a patient treated with abiraterone for castration-resistant prostate cancer.
Topics: Aged, 80 and over; Androstenes; Antineoplastic Agents; Disease Progression; Drug Substitution; Heart Failure; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2019 |
Low-Fat Abiraterone Food Effect Is of Great Consequence.
Topics: Abiraterone Acetate; Androstenes; Humans; Male; Prospective Studies; Prostatic Neoplasms, Castration-Resistant | 2018 |
Reply to I.F. Tannock, P. Isaacsson Velho et al, M. Tiako Meyo et al, and F.J.S.H. Woei-A-Jin et al.
Topics: Androstenes; Humans; Male; Prospective Studies; Prostatic Neoplasms, Castration-Resistant | 2018 |
Low-Dose Abiraterone With Food: Rebutting an Editorial.
Topics: Abiraterone Acetate; Androstenes; Humans; Male; Prospective Studies; Prostatic Neoplasms, Castration-Resistant | 2018 |
There Is Now Compelling Evidence to Further Evaluate Lower Doses of Abiraterone Acetate in Men With Metastatic Prostate Cancer: It Should Be Safer, May Be as Effective and Less Expensive.
Topics: Abiraterone Acetate; Androstenes; Humans; Male; Prospective Studies; Prostatic Neoplasms, Castration-Resistant | 2018 |
Low-Dose Abiraterone Regimen: Drug Monitoring Might Be the Key.
Topics: Abiraterone Acetate; Androstenes; Drug Monitoring; Humans; Male; Prospective Studies; Prostatic Neoplasms, Castration-Resistant | 2018 |
Dose Reduction May Jeopardize Efficacy of Abiraterone Acetate.
Topics: Abiraterone Acetate; Androstenes; Humans; Male; Prospective Studies; Prostatic Neoplasms, Castration-Resistant | 2018 |
Reply to I.F. Tannock, P. Isaacsson Velho et al, R.Z. Szmulewitz et al, M. Tiako Meyo et al, and F.J.S.H. Woei-A-Jin et al.
Topics: Androstenes; Humans; Male; Prospective Studies; Prostatic Neoplasms, Castration-Resistant | 2018 |
Is combining PARP and androgen receptor inhibition really a winning strategy in metastatic castration-resistant prostate cancer?
Topics: Androstenes; Double-Blind Method; Humans; Male; Phthalazines; Piperazines; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen | 2018 |
Real-world outcomes in patients with metastatic castration-resistant prostate cancer receiving second-line chemotherapy versus an alternative androgen receptor-targeted agent (ARTA) following early progression on a first-line ARTA in a US community oncolo
Topics: Aged; Androgen Antagonists; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Disease Progression; Disease-Free Survival; Docetaxel; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Proportional Hazards Models; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Taxoids; Treatment Outcome | 2018 |
Precision Medicine Approaches When Prostate Cancer Akts Up.
Topics: Androstenes; Humans; Male; Precision Medicine; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptors, Androgen | 2019 |
Phosphorylation of androgen receptor serine 81 is associated with its reactivation in castration-resistant prostate cancer.
Topics: Androstenes; Animals; Benzamides; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Mice, Inbred ICR; Mice, SCID; Nitriles; Phenylthiohydantoin; Phosphorylation; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Serine; Xenograft Model Antitumor Assays | 2018 |
Evaluation of Response to Enzalutamide Consecutively After Abiraterone Acetate/Prednisone Failure in Patients With Metastatic Castration-resistant Prostate Cancer.
Topics: Abiraterone Acetate; Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Disease Progression; Drug Resistance, Neoplasm; Humans; Kallikreins; Kaplan-Meier Estimate; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prednisone; Progression-Free Survival; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Time Factors; Treatment Failure; Treatment Outcome | 2018 |
Downregulation of
Topics: Alternative Splicing; Androgen Antagonists; Androstenes; Animals; Benzamides; Cell Line, Tumor; Dipeptidyl Peptidase 4; Disease Progression; Down-Regulation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Profiling; Humans; Male; Mice; Mice, SCID; Neoplasm Recurrence, Local; Neoplasm Transplantation; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; RNA, Small Interfering; Signal Transduction; Sitagliptin Phosphate | 2018 |
Optimal control to develop therapeutic strategies for metastatic castrate resistant prostate cancer.
Topics: Androstenes; Disease Management; Disease Progression; Dose-Response Relationship, Drug; Drug Resistance; Game Theory; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Quality of Life | 2018 |
Expression of Androgen Receptor Variant 7 (AR-V7) in Circulated Tumor Cells and Correlation with Drug Resistance of Prostate Cancer Cells.
Topics: Adult; Aged; Androstenes; Benzamides; Case-Control Studies; Drug Resistance, Neoplasm; Humans; Male; Middle Aged; Neoplastic Cells, Circulating; Nitriles; Phenylthiohydantoin; Prognosis; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; RNA, Messenger | 2018 |
Lessons from the SWITCH trial: changing glucocorticoids in the management of metastatic castration-resistant prostate cancer (mCRPC).
Topics: Abiraterone Acetate; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Glucocorticoids; Humans; Male; Pilot Projects; Prednisone; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant | 2018 |
Re: Germline DNA-Repair Gene Mutations and Outcomes in Men with Metastatic Castration-Resistant Prostate Cancer Receiving First-Line Abiraterone and Enzalutamide.
Topics: Androstenes; Benzamides; DNA; Germ Cells; Humans; Male; Mutation; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant | 2018 |
Serum testosterone level as possible predictive marker in androgen receptor axis-targeting agents and taxane chemotherapies for castration-resistant prostate cancer.
Topics: Aged; Androgen Antagonists; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomarkers, Tumor; Docetaxel; Humans; Kaplan-Meier Estimate; Male; Neoplasm Grading; Nitriles; Phenylthiohydantoin; Progression-Free Survival; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Taxoids; Testosterone | 2019 |
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer.
Topics: Androstenes; Angiogenesis Inhibitors; Animals; Benzamides; Cell Line, Tumor; HSP70 Heat-Shock Proteins; Humans; Male; Mice; Molecular Docking Simulation; Neoplasm Grading; Nitriles; Phenylthiohydantoin; Prostate; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Proteasome Endopeptidase Complex; Proteostasis; Receptors, Androgen; Ubiquitin; Ubiquitin-Protein Ligases; Ubiquitination | 2018 |
Impact of timing of administration of bone supportive therapy on pain palliation from radium-223.
Topics: Androstenes; Benzamides; Bone Density Conservation Agents; Bone Neoplasms; Cancer Pain; Chemoradiotherapy; Follow-Up Studies; Humans; Male; Nitriles; Pain Management; Palliative Care; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Radium; Retrospective Studies; Time Factors | 2019 |
Topics: Androstenes; Benzamides; Biomarkers, Tumor; Humans; Male; Neoplastic Cells, Circulating; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Tumor Suppressor Protein p53 | 2019 |
Hard Problems Need "Soft" Science: Integrating Quality of Life into Treatment Decision Making.
Topics: Androstenes; Benzamides; Decision Making; Humans; Male; Nitriles; Phenylthiohydantoin; Prednisone; Prostatic Neoplasms, Castration-Resistant; Quality of Life | 2019 |
Re: Olaparib Combined with Abiraterone in Patients with Metastatic Castration-Resistant Prostate Cancer: A Randomised, Double-Blind, Placebo-Controlled, Phase 2 Trial.
Topics: Androstenes; Double-Blind Method; Humans; Male; Phthalazines; Piperazines; Prostatic Neoplasms, Castration-Resistant | 2019 |
Higher Risk of Fragility Fractures in Prostate Cancer Patients Treated with Combined Radium-223 and Abiraterone: Prednisone May Be the Culprit.
Topics: Abiraterone Acetate; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Fractures, Bone; Humans; Male; Prednisone; Prostatic Neoplasms, Castration-Resistant; Radium; Treatment Outcome | 2019 |
Plasma Androgen Receptor and Docetaxel for Metastatic Castration-resistant Prostate Cancer.
Topics: Androgen Antagonists; Androstenes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Docetaxel; Humans; Kallikreins; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Progression-Free Survival; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Spain; Time Factors | 2019 |
Inhibition of Autophagy Improves the Efficacy of Abiraterone for the Treatment of Prostate Cancer.
Topics: Adenine; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Male; Prostatic Neoplasms, Castration-Resistant | 2019 |
Clinical utility of androgen receptor gene aberrations in circulating cell-free DNA as a biomarker for treatment of castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Animals; Antineoplastic Agents, Hormonal; Benzamides; Biomarkers, Tumor; Cell Line, Tumor; Cell-Free Nucleic Acids; Drug Resistance, Neoplasm; Gene Dosage; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Mutation; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Treatment Outcome | 2019 |
Evaluation of the possible interference of abiraterone therapy on testosterone immunoassay.
Topics: Abiraterone Acetate; Androstenes; Artifacts; Clinical Laboratory Techniques; Humans; Immunoassay; Male; Prostatic Neoplasms, Castration-Resistant; Testosterone | 2019 |
Association of prostate cancer SLCO gene expression with Gleason grade and alterations following androgen deprivation therapy.
Topics: Adult; Aged; Androgen Antagonists; Androstenes; Dehydroepiandrosterone Sulfate; Disease Progression; Docetaxel; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Male; Middle Aged; Neoplasm Grading; Organic Anion Transporters; Prostate; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms, Castration-Resistant; Solute Carrier Organic Anion Transporter Family Member 1B3; Testosterone; Treatment Outcome | 2019 |
Multidrug Cancer Therapy in Metastatic Castrate-Resistant Prostate Cancer: An Evolution-Based Strategy.
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Administration Schedule; Drug Resistance, Neoplasm; Humans; Male; Models, Theoretical; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Simulation Training; Survival Rate; Treatment Outcome | 2019 |
Impact of the introduction of novel hormonal agents on metastatic castration-resistant prostate cancer treatment choice.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Benzamides; Clinical Decision-Making; Cohort Studies; Docetaxel; Humans; Male; Nitriles; Patient Selection; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2020 |
Pseudoprogression on PSMA PET imaging of a mCRPC patient under anti-PD1 treatment.
Topics: Aged, 80 and over; Androstenes; Anilides; Antibodies, Monoclonal, Humanized; Antigens, Surface; Brachytherapy; Disease Progression; Gallium Radioisotopes; Gene Expression Regulation, Neoplastic; Glutamate Carboxypeptidase II; Goserelin; Humans; Ligands; Male; Nitriles; Positron-Emission Tomography; Programmed Cell Death 1 Receptor; Prostatectomy; Prostatic Neoplasms, Castration-Resistant; Salvage Therapy; Tosyl Compounds | 2019 |
Early use of abiraterone and radium-223 in metastatic prostate cancer.
Topics: Abiraterone Acetate; Androstenes; Double-Blind Method; Humans; Male; Prednisolone; Prednisone; Prostatic Neoplasms, Castration-Resistant; Radium | 2019 |
Early use of abiraterone and radium-223 in metastatic prostate cancer.
Topics: Abiraterone Acetate; Androstenes; Double-Blind Method; Humans; Male; Prednisolone; Prednisone; Prostatic Neoplasms, Castration-Resistant; Radium | 2019 |
Genomic correlates of clinical outcome in advanced prostate cancer.
Topics: Aged; Androstenes; Benzamides; Biomarkers, Tumor; Drug Resistance, Neoplasm; Genomics; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Treatment Outcome | 2019 |
Inter- and intra-patient variability in pharmacokinetics of abiraterone acetate in metastatic prostate cancer.
Topics: Abiraterone Acetate; Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Fasting; Humans; Longitudinal Studies; Male; Middle Aged; Neoplasm Metastasis; Prednisone; Prospective Studies; Prostatic Neoplasms, Castration-Resistant | 2019 |
Treatment of Metastatic Castration-resistant Prostate Cancer With Abiraterone and Enzalutamide Despite PSA Progression.
Topics: Aged; Androstenes; Benzamides; Disease-Free Survival; Drug Resistance, Neoplasm; Humans; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Terminal Care; Treatment Outcome | 2019 |
Serum testosterone level is a useful biomarker for determining the optimal treatment for castration-resistant prostate cancer.
Topics: Aged; Androgen Antagonists; Androstenes; Benzamides; Biomarkers, Tumor; Clinical Decision-Making; Disease Progression; Drug Resistance, Neoplasm; Feasibility Studies; Follow-Up Studies; Humans; Kallikreins; Male; Neoplasm Grading; Nitriles; Patient Selection; Phenylthiohydantoin; Progression-Free Survival; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Testosterone; Time Factors | 2019 |
Adoption of Abiraterone and Enzalutamide by Urologists.
Topics: Androstenes; Benzamides; Drug Prescriptions; Humans; Male; Medicaid; Medicare; Nitriles; Phenylthiohydantoin; Practice Patterns, Physicians'; Prostatic Neoplasms, Castration-Resistant; United States; Urology | 2019 |
Early prostate-specific antigen response post-abiraterone as predictor of overall survival in metastatic castrate-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Docetaxel; Humans; Leukocyte Count; Lymphocytes; Male; Middle Aged; Neutrophils; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Rate; Time Factors | 2019 |
Wnt-pathway Activating Mutations Are Associated with Resistance to First-line Abiraterone and Enzalutamide in Castration-resistant Prostate Cancer.
Topics: Aged; Androstenes; Benzamides; Drug Resistance, Neoplasm; Humans; Male; Middle Aged; Mutation; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome; Wnt Signaling Pathway | 2020 |
Efficacy, Tolerance, and Plasma Levels of Abiraterone and Its Main Metabolites in a Patient With Metastatic Castration-resistant Prostate Cancer With a Hepatic Transplant.
Topics: Abiraterone Acetate; Aged; Androstenes; Feasibility Studies; Humans; Liver Transplantation; Male; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2019 |
Testosterone levels and androgen receptor copy number variations in castration-resistant prostate cancer treated with abiraterone or enzalutamide.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Benzamides; DNA Copy Number Variations; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prognosis; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Retrospective Studies; Survival Rate; Testosterone | 2019 |
Circulating Tumor Cell-Based Molecular Classifier for Predicting Resistance to Abiraterone and Enzalutamide in Metastatic Castration-Resistant Prostate Cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomarkers, Tumor; Computational Biology; Drug Resistance, Neoplasm; Gene Expression Profiling; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Grading; Neoplasm Metastasis; Neoplasm Staging; Neoplastic Cells, Circulating; Nitriles; Phenylthiohydantoin; Prognosis; Proportional Hazards Models; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2019 |
AKR1C3 expression in primary lesion rebiopsy at the time of metastatic castration-resistant prostate cancer is strongly associated with poor efficacy of abiraterone as a first-line therapy.
Topics: Aged; Aldo-Keto Reductase Family 1 Member C3; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Resistance, Neoplasm; Humans; Image-Guided Biopsy; Immunohistochemistry; Male; Neoplasm Metastasis; Prednisone; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies | 2019 |
Characterizing the Wnt Pathway in Advanced Prostate Cancer: When, Why, and How.
Topics: Androstenes; Benzamides; Humans; Male; Mutation; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Wnt Signaling Pathway | 2020 |
Early Post-treatment Prostate-specific Antigen at 4 Weeks and Abiraterone and Enzalutamide Treatment for Advanced Prostate Cancer: An International Collaborative Analysis.
Topics: Androstenes; Benzamides; Humans; Male; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Analysis; Time Factors; Treatment Outcome | 2020 |
Management of castrate resistant prostate cancer-recent advances and optimal sequence of treatments.
Topics: Androstenes; Androstenols; Anilides; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Disease-Free Survival; Humans; Imidazoles; Ipilimumab; Male; Naphthalenes; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Pyridines; Quinolines; Quinolones; Radioisotopes; Radium; Taxoids; Thionucleotides; Tissue Extracts | 2013 |
Improved therapeutic targeting of the androgen receptor: rational drug design improves survival in castration-resistant prostate cancer.
Topics: Androgen Antagonists; Androgens; Androstenes; Androstenols; Benzamides; Castration; Chromosome Aberrations; Drug Design; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; RNA, Messenger; Signal Transduction; Steroid 17-alpha-Hydroxylase | 2013 |
Enzalutamide in castration-resistant prostate cancer patients progressing after docetaxel and abiraterone.
Topics: Aged; Aged, 80 and over; Androstenes; Androstenols; Antineoplastic Agents; Benzamides; Disease Progression; Docetaxel; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Pilot Projects; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Failure | 2014 |
The European medicines agency review of abiraterone for the treatment of metastatic castration-resistant prostate cancer in adult men after docetaxel chemotherapy and in chemotherapy-naive disease: summary of the scientific assessment of the committee for
Topics: Adult; Androstenes; Androstenols; Antineoplastic Agents; Clinical Trials, Phase III as Topic; Disease Progression; Docetaxel; Drug Approval; European Union; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Randomized Controlled Trials as Topic; Taxoids; Treatment Outcome | 2013 |
Antitumour activity of enzalutamide (MDV3100) in patients with metastatic castration-resistant prostate cancer (CRPC) pre-treated with docetaxel and abiraterone.
Topics: Aged; Aged, 80 and over; Androstenes; Androstenols; Benzamides; Docetaxel; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Taxoids; Treatment Outcome | 2014 |
Towards random sequencing or precision medicine in castration-resistant prostate cancer?
Topics: Androstenes; Androstenols; Antineoplastic Agents; Benzamides; Docetaxel; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2014 |
Cross-resistance between taxanes and new hormonal agents abiraterone and enzalutamide may affect drug sequence choices in metastatic castration-resistant prostate cancer.
Topics: Active Transport, Cell Nucleus; Androstenes; Androstenols; Benzamides; Blotting, Western; Cell Line, Tumor; Cell Nucleus; Cell Survival; Docetaxel; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Neoplasm; Green Fluorescent Proteins; Humans; Male; Microscopy, Confocal; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Taxoids; Time-Lapse Imaging | 2013 |
New therapeutic options in metastatic castration-resistant prostate cancer: Can cost-effectiveness analysis help in treatment decisions?
Topics: Androstenes; Antineoplastic Agents; Benzamides; Cost-Benefit Analysis; Decision Trees; Drug Costs; Financing, Personal; Humans; Male; Models, Economic; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Quality-Adjusted Life Years; Survival Rate; Taxoids | 2014 |
Clinical activity and tolerability of enzalutamide (MDV3100) in patients with metastatic, castration-resistant prostate cancer who progress after docetaxel and abiraterone treatment.
Topics: Aged; Androstenes; Androstenols; Antineoplastic Agents; Benzamides; Docetaxel; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Survival Analysis; Taxoids; Treatment Outcome | 2014 |
Abiraterone in heavily pretreated patients with metastatic castrate-resistant prostate cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androstenes; Androstenols; Antineoplastic Agents; Drug Therapy, Combination; Humans; Male; Mineralocorticoids; Prednisone; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Steroid 17-alpha-Hydroxylase | 2014 |
Activity of cabazitaxel in castration-resistant prostate cancer progressing after docetaxel and next-generation endocrine agents.
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Disease Progression; Disease-Free Survival; Docetaxel; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retreatment; Retrospective Studies; Survival Rate; Taxoids; Treatment Failure | 2014 |
Enzalutamide after docetaxel and abiraterone therapy in metastatic castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Androstenes; Androstenols; Antineoplastic Agents; Benzamides; Bone Neoplasms; Compassionate Use Trials; Disease-Free Survival; Docetaxel; Humans; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Failure | 2014 |
The influence of prior abiraterone treatment on the clinical activity of docetaxel in men with metastatic castration-resistant prostate cancer.
Topics: Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cohort Studies; Disease Progression; Disease-Free Survival; Docetaxel; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Invasiveness; Neoplasm Staging; Proportional Hazards Models; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Risk Assessment; Survival Rate; Taxoids; Treatment Outcome | 2014 |
Abiraterone--what is wrong with the adrenal glands?
Topics: Adrenal Gland Neoplasms; Androgen Antagonists; Androstenes; Humans; Male; Middle Aged; Prognosis; Prostatic Neoplasms, Castration-Resistant | 2014 |
One size does not fit all: can we choose the best sequence of treatment in asymptomatic castration-resistant prostate cancer patients?
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Docetaxel; Humans; Lung Neoplasms; Male; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2014 |
Chromogranin A predicts outcome in prostate cancer patients treated with abiraterone.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androstenes; Androstenols; Biomarkers, Tumor; Bone Neoplasms; Chromogranin A; Enzyme-Linked Immunosorbent Assay; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Staging; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Rate | 2014 |
Cabazitaxel Remains Active in Patients Progressing After Docetaxel Followed by Novel Androgen Receptor Pathway Targeted Therapies.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease-Free Survival; Docetaxel; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; France; Humans; Kallikreins; Kaplan-Meier Estimate; Male; Middle Aged; Molecular Targeted Therapy; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Retrospective Studies; Signal Transduction; Taxoids; Time Factors; Treatment Outcome | 2015 |
The use of the EVITA algorithm for clinical assessment of novel agents used in prostate cancer, metastatic melanoma, and systemic lupus erythematosus.
Topics: Algorithms; Androstenes; Androstenols; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Cancer Vaccines; Humans; Immunosuppressive Agents; Ipilimumab; Lupus Erythematosus, Systemic; Male; Melanoma; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Radioisotopes; Radium; Randomized Controlled Trials as Topic; Skin Neoplasms; Tissue Extracts | 2014 |
Metastatic Castration-resistant Prostate Cancer: Piling Up the Benefits of Chemotherapy.
Topics: Androgen Antagonists; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Docetaxel; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Taxoids | 2015 |
PSA flare with abiraterone in patients with metastatic castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Disease-Free Survival; Humans; Italy; Male; Middle Aged; Neoplasm Metastasis; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Analysis; Treatment Outcome | 2015 |
Abiraterone acetate in metastatic castration-resistant prostate cancer: a retrospective review of the Princess Margaret experience of (I) low dose abiraterone and (II) prior ketoconazole.
Topics: Aged; Aged, 80 and over; Androstenes; Androstenols; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Dose-Response Relationship, Drug; Humans; Ketoconazole; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2014 |
Clinical activity of enzalutamide versus docetaxel in men with castration-resistant prostate cancer progressing after abiraterone.
Topics: Adenocarcinoma; Aged; Androstenes; Androstenols; Antineoplastic Agents; Benzamides; Bone Neoplasms; Disease Progression; Docetaxel; Drug Resistance, Neoplasm; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Taxoids; Treatment Outcome | 2014 |
Prostate cancer: the best fit for enzalutamide in metastatic prostate cancer.
Topics: Androstenes; Androstenols; Antineoplastic Agents; Benzamides; Docetaxel; Humans; Male; Neoplasm Metastasis; Nitriles; Patient Selection; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2014 |
Enzalutamide Antitumour Activity Against Metastatic Castration-resistant Prostate Cancer Previously Treated with Docetaxel and Abiraterone: A Multicentre Analysis.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Compassionate Use Trials; Disease Progression; Disease-Free Survival; Docetaxel; Drug Resistance, Neoplasm; Drug Substitution; Europe; Humans; Kallikreins; Kaplan-Meier Estimate; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Proportional Hazards Models; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Risk Factors; Taxoids; Time Factors; Treatment Outcome | 2015 |
Docetaxel followed by abiraterone in metastatic castration-resistant prostate cancer: efficacy and predictive parameters in a large single center cohort.
Topics: Aged; Androgen Antagonists; Androstenes; Anilides; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Buserelin; Cohort Studies; Disease-Free Survival; Docetaxel; Flutamide; Humans; Leuprolide; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Nitriles; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Taxoids; Tosyl Compounds; Treatment Outcome; Triptorelin Pamoate | 2015 |
[Abiraterone acetate(ZYTIGA®)-development and literature review].
Topics: Abiraterone Acetate; Androstadienes; Androstenes; Androstenols; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Enzyme Inhibitors; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Steroid 17-alpha-Hydroxylase | 2014 |
Limited in vitro efficacy of CYP17A1 inhibition on human castration resistant prostate cancer.
Topics: Androstenes; Cell Line, Tumor; Enzyme Activation; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Real-Time Polymerase Chain Reaction; Steroid 17-alpha-Hydroxylase; Tandem Mass Spectrometry | 2014 |
A retrospective, Canadian multi-center study examining the impact of prior response to abiraterone acetate on efficacy of docetaxel in metastatic castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Androstenols; Antineoplastic Agents; Canada; Cytochrome P-450 Enzyme Inhibitors; Disease-Free Survival; Docetaxel; Humans; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Analysis; Taxoids; Treatment Outcome | 2014 |
Secondary hormone therapy for castration-resistant prostate cancer.
Topics: Androgen Antagonists; Androstenes; Benzamides; Drug Resistance, Neoplasm; Humans; Male; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant | 2013 |
Real-world experience with abiraterone.
Topics: Androstenes; Androstenols; Humans; Male; Neoplasm Recurrence, Local; Prednisolone; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant | 2014 |
Efficacy and toxicity of abiraterone and docetaxel in octogenarians with metastatic castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Disease-Free Survival; Docetaxel; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Rate; Taxoids; Treatment Outcome | 2015 |
New targets for resistant prostate cancer.
Topics: Androgen Receptor Antagonists; Androstenes; Benzamides; beta Catenin; Humans; Male; Nitriles; Phenylthiohydantoin; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myb; Receptors, Androgen; Receptors, Glucocorticoid; Signal Transduction; Wnt Proteins | 2014 |
Cost-effectiveness analysis of abiraterone and sipuleucel-T in asymptomatic metastatic castration-resistant prostate cancer.
Topics: Androstenes; Asymptomatic Diseases; Bone Neoplasms; Cost-Benefit Analysis; Disease-Free Survival; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Quality of Life; Tissue Extracts | 2014 |
Tumour responses following a steroid switch from prednisone to dexamethasone in castration-resistant prostate cancer patients progressing on abiraterone.
Topics: Aged; Aged, 80 and over; Androstenes; Anti-Inflammatory Agents; Dexamethasone; Humans; Male; Middle Aged; Prednisone; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2014 |
Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; DNA Helicases; DNA-Binding Proteins; Drug Resistance, Neoplasm; Dutasteride; Humans; Ketoconazole; Leuprolide; Male; Middle Aged; Mutation; Progesterone; Prostatic Neoplasms, Castration-Resistant; PTEN Phosphohydrolase; Receptors, Androgen; Steroid 17-alpha-Hydroxylase | 2015 |
Androgen deprivation therapy sensitizes prostate cancer cells to T-cell killing through androgen receptor dependent modulation of the apoptotic pathway.
Topics: Androgen Antagonists; Androstenes; Animals; Apoptosis; Benzamides; Cell Line, Tumor; Disease Progression; Humans; Immunomodulation; Immunotherapy; Male; Mice; Neuronal Apoptosis-Inhibitory Protein; Nitriles; Phenylthiohydantoin; Prostate; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; RNA Interference; RNA, Small Interfering; T-Lymphocytes | 2014 |
Anticancer activity of a novel selective CYP17A1 inhibitor in preclinical models of castrate-resistant prostate cancer.
Topics: Androstenes; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Naphthalenes; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Signal Transduction; Steroid 17-alpha-Hydroxylase; Triazoles; Xenograft Model Antitumor Assays | 2015 |
Predicting treatment response in castration-resistant prostate cancer: could androgen receptor variant-7 hold the key?
Topics: Alternative Splicing; Androstenes; Antineoplastic Agents; Benzamides; Drug Resistance, Neoplasm; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Treatment Outcome | 2015 |
Activity of enzalutamide in men with metastatic castration-resistant prostate cancer is affected by prior treatment with abiraterone and/or docetaxel.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Disease-Free Survival; Docetaxel; Humans; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Taxoids; Treatment Outcome | 2015 |
Abiraterone's efficacy confirmed; time to aim higher.
Topics: Androstenes; Antineoplastic Agents, Hormonal; Bone Neoplasms; Humans; Male; Prednisone; Prostatic Neoplasms, Castration-Resistant | 2015 |
Exploring the Clinical Benefit of Docetaxel or Enzalutamide After Disease Progression During Abiraterone Acetate and Prednisone Treatment in Men With Metastatic Castration-Resistant Prostate Cancer.
Topics: Abiraterone Acetate; Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Benzamides; Disease Progression; Disease-Free Survival; Docetaxel; Drug Resistance, Neoplasm; Humans; Kallikreins; Kaplan-Meier Estimate; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prednisone; Proportional Hazards Models; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Radiography; Retrospective Studies; Taxoids; Treatment Outcome | 2015 |
Androgen Receptor Gene Aberrations in Circulating Cell-Free DNA: Biomarkers of Therapeutic Resistance in Castration-Resistant Prostate Cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Biomarkers, Tumor; Disease-Free Survival; DNA Copy Number Variations; DNA Mutational Analysis; DNA, Neoplasm; Docetaxel; Drug Resistance, Neoplasm; High-Throughput Nucleotide Sequencing; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Mutation, Missense; Neoplasm Metastasis; Neoplastic Cells, Circulating; Proportional Hazards Models; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Taxoids | 2015 |
Androgen receptor expression in circulating tumour cells from castration-resistant prostate cancer patients treated with novel endocrine agents.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Benzamides; Cell Line, Tumor; Disease Progression; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplastic Cells, Circulating; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen | 2015 |
A HPLC-fluorescence method for the quantification of abiraterone in plasma from patients with metastatic castration-resistant prostate cancer.
Topics: Androstenes; Chromatography, High Pressure Liquid; Humans; Male; Prostatic Neoplasms, Castration-Resistant | 2015 |
[Some questions about abiraterone, breakfast and public funding].
Topics: Androgen Receptor Antagonists; Androstenes; Breakfast; Drug Costs; Humans; Male; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant | 2015 |
Circulating cell-free AR and CYP17A1 copy number variations may associate with outcome of metastatic castration-resistant prostate cancer patients treated with abiraterone.
Topics: Aged; Aged, 80 and over; Androstenes; Case-Control Studies; Disease-Free Survival; DNA; DNA Copy Number Variations; Humans; Kallikreins; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Retrospective Studies; Steroid 17-alpha-Hydroxylase | 2015 |
Biological and clinical effects of abiraterone on anti-resorptive and anabolic activity in bone microenvironment.
Topics: Alkaline Phosphatase; Androstenes; Antineoplastic Agents; Blotting, Western; Bone and Bones; Bone Remodeling; Cell Differentiation; Collagen Type I; Enzyme-Linked Immunosorbent Assay; Humans; Male; Osteoblasts; Osteoclasts; Peptides; Prostatic Neoplasms, Castration-Resistant; Real-Time Polymerase Chain Reaction; Transcriptome | 2015 |
[Abiraterone: Overall survival benefit and subsidiary issues].
Topics: Androstenes; Antineoplastic Agents, Hormonal; Humans; Male; Prostatic Neoplasms, Castration-Resistant | 2015 |
Metabolic syndrome in castration-resistant prostate cancer patients treated with abiraterone.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Disease Progression; Disease-Free Survival; Enzyme Inhibitors; Humans; Male; Metabolic Syndrome; Middle Aged; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Risk Factors; Steroid 17-alpha-Hydroxylase; Survival Rate; Treatment Outcome | 2015 |
Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer.
Topics: 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androgen Receptor Antagonists; Androgens; Androstenes; Animals; Benzamides; Biosynthetic Pathways; Biotransformation; Cell Division; Chromatin; Dihydrotestosterone; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Steroid 17-alpha-Hydroxylase; Survival Analysis; Xenograft Model Antitumor Assays | 2015 |
Tolerability of cabazitaxel in patients with metastatic castration-resistant prostate cancer progressing after docetaxel and abiraterone acetate: a single-institution experience.
Topics: Aged; Androstenes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Endpoint Determination; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Taxoids; Treatment Failure | 2015 |
Serial blood-based analysis of AR-V7 in men with advanced prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Benzamides; Biomarkers, Tumor; Docetaxel; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplastic Cells, Circulating; Nitriles; Phenylthiohydantoin; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Taxoids; Treatment Outcome | 2015 |
[Non-interventional study of metastatic castration-resistant prostate cancer. Prospective, non-interventional trial on the influence of adherence to abiraterone treatment in patients with metastatic, castrate-resistant prostate cancer (IMPACT) - trial AP
Topics: Administration, Oral; Androstenes; Antineoplastic Agents; Carcinoma; Germany; Humans; Male; Medication Adherence; Prevalence; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Risk Factors; Treatment Outcome | 2015 |
[A case of metastatic castration-resistant prostate cancer by abiraterone treatment].
Topics: Androstenes; Bone Neoplasms; Disease Progression; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant | 2015 |
Androgen Receptor Splice Variant 7 and Efficacy of Taxane Chemotherapy in Patients With Metastatic Castration-Resistant Prostate Cancer.
Topics: Academic Medical Centers; Adenocarcinoma; Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Baltimore; Benzamides; Biomarkers, Tumor; Disease-Free Survival; Docetaxel; Drug Resistance, Neoplasm; Genetic Predisposition to Disease; Humans; Kallikreins; Kaplan-Meier Estimate; Male; Middle Aged; Neoplastic Cells, Circulating; Nitriles; Patient Selection; Phenotype; Phenylthiohydantoin; Predictive Value of Tests; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen; Risk Factors; RNA, Messenger; Taxoids; Time Factors; Treatment Outcome | 2015 |
Abiraterone in heavily pretreated patients with metastatic castrate-resistant prostate cancer: final analysis of overall survival.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Survival Analysis | 2015 |
Rhabdomyolysis-induced acute kidney injury in a cancer patient exposed to denosumab and abiraterone: a case report.
Topics: Acute Kidney Injury; Aged; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Denosumab; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Prostatic Neoplasms, Castration-Resistant; Rhabdomyolysis; Rosuvastatin Calcium | 2015 |
Optimal sequencing of docetaxel and abiraterone in men with metastatic castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Docetaxel; Drug Administration Schedule; Humans; Male; Middle Aged; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Taxoids; Treatment Outcome | 2015 |
Prognostic parameters for response to enzalutamide after docetaxel and abiraterone treatment in metastatic castration-resistant prostate cancer patients; a possible time relation.
Topics: Aged; Androstenes; Antineoplastic Agents; Benzamides; Disease-Free Survival; Docetaxel; Drug Monitoring; Drug Resistance, Neoplasm; Drug Substitution; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Netherlands; Nitriles; Phenylthiohydantoin; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Taxoids; Treatment Outcome | 2016 |
What Predicts Minimal Response to Abiraterone in Metastatic Castrate-resistant Prostate Cancer?
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Androstenes; Disease-Free Survival; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Rate | 2015 |
Impact of visceral metastases on outcome to abiraterone after docetaxel in castration-resistant prostate cancer patients.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Survival Analysis; Taxoids; Treatment Outcome; Viscera | 2015 |
Impact of a pharmacist-led oral chemotherapy-monitoring program in patients with metastatic castrate-resistant prostate cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Androstenes; Androstenols; Antineoplastic Agents; Benzamides; Cohort Studies; Drug Monitoring; Humans; Male; Middle Aged; Nitriles; Pharmacists; Phenylthiohydantoin; Professional Role; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2016 |
Plasma AR and abiraterone-resistant prostate cancer.
Topics: Adult; Aged; Aged, 80 and over; Androstenes; DNA Copy Number Variations; Drug Resistance, Neoplasm; Humans; Male; Middle Aged; Point Mutation; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Young Adult | 2015 |
Clinical Relevance of Androgen Receptor Splice Variants in Castration-Resistant Prostate Cancer.
Topics: Androstenes; Androstenols; Benzamides; Bridged-Ring Compounds; Docetaxel; Drug Resistance, Neoplasm; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen; Taxoids | 2015 |
Abiraterone-induced rhabdomyolysis: A case report.
Topics: Analgesics, Opioid; Androstenes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Constipation; Creatine Kinase; Cytochrome P450 Family 17; Drug Therapy, Combination; Humans; Injections, Spinal; Male; Middle Aged; Morphine; Nausea; Pain Management; Prednisone; Prostatic Neoplasms, Castration-Resistant; Rhabdomyolysis; Vomiting | 2017 |
Metastasis: Resistance fighters.
Topics: Alternative Splicing; Androgen Antagonists; Androstenes; Benzamides; DNA Repair; Drug Resistance, Neoplasm; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Thionucleotides | 2015 |
Singapore Cancer Network (SCAN) Guidelines for the Management of Advanced Castrate-Resistant Prostate Cancer.
Topics: Adenocarcinoma; Androgen Antagonists; Androstenes; Antineoplastic Agents; Benzamides; Cancer Vaccines; Docetaxel; Gonadotropin-Releasing Hormone; Humans; Ketoconazole; Male; Nitriles; Orchiectomy; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Radioisotopes; Radium; Singapore; Taxoids; Tissue Extracts | 2015 |
A prospective study examining elder-relevant outcomes in older adults with prostate cancer undergoing treatment with chemotherapy or abiraterone.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Cytochrome P-450 Enzyme Inhibitors; Hand Strength; Humans; Male; Pilot Projects; Prospective Studies; Prostatic Neoplasms, Castration-Resistant; Surveys and Questionnaires | 2016 |
The influence of prednisone on the efficacy of docetaxel in men with metastatic castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Docetaxel; Humans; Ketoconazole; Male; Middle Aged; Neoplasm Metastasis; Prednisone; Proportional Hazards Models; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Taxoids; Treatment Outcome | 2016 |
ErbB2 Signaling Increases Androgen Receptor Expression in Abiraterone-Resistant Prostate Cancer.
Topics: Androgens; Androstenes; Animals; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Leuprolide; Male; Mice; Mice, SCID; Phosphatidylinositol 3-Kinases; Prostate; Prostatic Neoplasms, Castration-Resistant; Receptor, ErbB-2; Receptors, Androgen; Signal Transduction; Xenograft Model Antitumor Assays | 2016 |
CYP17A1 polymorphisms and clinical outcome of castration-resistant prostate cancer patients treated with abiraterone.
Topics: Aged; Aged, 80 and over; Androstenes; Disease-Free Survival; Enzyme Inhibitors; Humans; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Risk Factors; Steroid 17-alpha-Hydroxylase; Treatment Outcome | 2016 |
A single-center experience with abiraterone as treatment for metastatic castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Androstenes; Antineoplastic Agents; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2016 |
Dynamic changes of alkaline phosphatase are strongly associated with PSA-decline and predict best clinical benefit earlier than PSA-changes under therapy with abiraterone acetate in bone metastatic castration resistant prostate cancer.
Topics: Aged; Alkaline Phosphatase; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms; Disease-Free Survival; Humans; Kaplan-Meier Estimate; L-Lactate Dehydrogenase; Male; Middle Aged; Neoplasm Metastasis; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2016 |
Chromogranin A and neurone-specific enolase serum levels as predictors of treatment outcome in patients with metastatic castration-resistant prostate cancer undergoing abiraterone therapy.
Topics: Aged; Aged, 80 and over; Androstenes; Chromogranin A; Disease-Free Survival; Humans; Male; Middle Aged; Neoplasm Metastasis; Phosphopyruvate Hydratase; Predictive Value of Tests; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2017 |
Niclosamide enhances abiraterone treatment via inhibition of androgen receptor variants in castration resistant prostate cancer.
Topics: Androgen Antagonists; Androstenes; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Genetic Variation; Humans; Male; Mice, SCID; Niclosamide; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; RNA Interference; Time Factors; Transfection; Tumor Burden; Xenograft Model Antitumor Assays | 2016 |
Third-line Enzalutamide Following Docetaxel and Abiraterone in Metastatic Castrate-resistant Prostate Cancer.
Topics: Aged; Androstenes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Docetaxel; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Outcome | 2016 |
[Not Available].
Topics: Administration, Oral; Adult; Aged; Androstenes; Disease Progression; Drug Approval; Follow-Up Studies; Germany; Humans; Male; Medication Adherence; Middle Aged; Physician-Patient Relations; Prostatic Neoplasms, Castration-Resistant | 2016 |
[Enzalutamide and Abiraterone in the Treatment of Metastatic Castration-resistant Prostate Cancer after Chemotherapy].
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Benzamides; Humans; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies | 2016 |
Analytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Prostate Cancer.
Topics: Aged; Androstenes; Antibodies, Monoclonal; Antineoplastic Agents; Benzamides; Biopsy; Cell Line, Tumor; Cell Nucleus; Drug Resistance, Neoplasm; Humans; Immunohistochemistry; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prognosis; Prostate; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen; Retrospective Studies; Survival Rate; Time Factors | 2016 |
The Effect of Time to Castration Resistance on Outcomes With Abiraterone and Enzalutamide in Metastatic Prostate Cancer.
Topics: Adult; Aged; Aged, 80 and over; Androgen Antagonists; Androstenes; Benzamides; Disease Progression; Disease-Free Survival; Humans; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Regression Analysis; Survival Analysis; Treatment Outcome | 2016 |
Predictors of long-term response to abiraterone in patients with metastastic castration-resistant prostate cancer: a retrospective cohort study.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Biomarkers, Tumor; Docetaxel; Follow-Up Studies; Humans; Italy; Male; Middle Aged; Neoplasm Metastasis; Proportional Hazards Models; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Taxoids | 2016 |
Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Abiraterone Acetate; Administration, Oral; Androgen Antagonists; Androgens; Androstenes; Animals; Cell Line, Tumor; Disease Progression; Dutasteride; Humans; Male; Mice; Oxidation-Reduction; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Xenograft Model Antitumor Assays | 2016 |
Bilateral Choroidal Metastases from Prostate Cancer revealed in a patient under Abiraterone - Fourteen years after diagnosis.
Topics: Androstenes; Antineoplastic Agents; Disease Progression; Humans; Male; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2016 |
Decline in Circulating Tumor Cell Count and Treatment Outcome in Advanced Prostate Cancer.
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Cell Count; Clinical Trials as Topic; Humans; Kaplan-Meier Estimate; Logistic Models; Male; Multivariate Analysis; Neoplasm Metastasis; Neoplastic Cells, Circulating; Prednisone; Proportional Hazards Models; Prostatic Neoplasms, Castration-Resistant | 2016 |
Could Steroidal Abiraterone Metabolites Possibly Explain Abiraterone Withdrawal Syndrome?
Topics: Abiraterone Acetate; Androstenes; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Substance Withdrawal Syndrome | 2016 |
[Abiraterone (CYP17 inhibitor)].
Topics: Androgens; Androstenes; Clinical Trials as Topic; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Steroid 17-alpha-Hydroxylase | 2016 |
[Overview of the ongoing clinical trials for new treatments for castrate-resistant prostate cancer (CRPC)].
Topics: Androstenes; Benzamides; Clinical Trials as Topic; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant | 2016 |
Current understanding of resistance to abiraterone and enzalutamide in advanced prostate cancer.
Topics: Androstenes; Antineoplastic Agents; Benzamides; Biomarkers; Clinical Trials as Topic; Drug Resistance, Neoplasm; Humans; Male; Neoplasm Staging; Nitriles; Phenylthiohydantoin; Prognosis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Treatment Outcome | 2016 |
Cost-Savings Analysis of AR-V7 Testing in Patients With Metastatic Castration-Resistant Prostate Cancer Eligible for Treatment With Abiraterone or Enzalutamide.
Topics: Androstenes; Benzamides; Biomarkers; Bridged-Ring Compounds; Cost Savings; Costs and Cost Analysis; Drug Resistance, Neoplasm; Humans; Male; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen; Taxoids | 2016 |
Do we need new trials for the abiraterone, enzalutamide and cabazitaxel in metastatic castrate-resistant prostate cancer for confirmation of treatment indications?
Topics: Androgen Antagonists; Androstenes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Clinical Trials, Phase III as Topic; Docetaxel; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Taxoids | 2017 |
AR-V7 Transcripts in Whole Blood RNA of Patients with Metastatic Castration Resistant Prostate Cancer Correlate with Response to Abiraterone Acetate.
Topics: Age Factors; Aged; Analysis of Variance; Androstenes; Biomarkers, Tumor; Case-Control Studies; Disease-Free Survival; Humans; Male; Middle Aged; Molecular Targeted Therapy; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Reproducibility of Results; Risk Assessment; RNA, Messenger; Survival Analysis; Treatment Outcome | 2017 |
Expression of AR-V7 in Circulating Tumour Cells Does Not Preclude Response to Next Generation Androgen Deprivation Therapy in Patients with Castration Resistant Prostate Cancer.
Topics: Androgen Receptor Antagonists; Androstenes; Benzamides; Drug Resistance, Neoplasm; Humans; Male; Neoplastic Cells, Circulating; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen; Retrospective Studies | 2017 |
Comparing Sequencing of Abiraterone and Enzalutamide in Men With Metastatic Castration-Resistant Prostate Cancer: A Retrospective Study.
Topics: Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Drug Administration Schedule; Humans; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Retrospective Studies; Treatment Outcome | 2017 |
Abiraterone for castration-resistant prostate cancer: adherence, survival and hospitalization : Analysis of a medical claims database.
Topics: Administration, Oral; Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents; Austria; Hospital Mortality; Hospitalization; Humans; Insurance Claim Review; Male; Medication Adherence; Middle Aged; Prevalence; Prostatic Neoplasms, Castration-Resistant; Risk Factors; Survival Rate; Treatment Outcome | 2017 |
The Detection of Androgen Receptor Splice Variant 7 in Plasma-derived Exosomal RNA Strongly Predicts Resistance to Hormonal Therapy in Metastatic Prostate Cancer Patients.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents, Hormonal; Benzamides; Disease-Free Survival; Drug Resistance, Neoplasm; Humans; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen; RNA | 2017 |
Re: Redirecting Abiraterone Metabolism to Fine-Tune Prostate Cancer Anti-Androgen Therapy.
Topics: Abiraterone Acetate; Androstenes; Humans; Male; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen | 2016 |
Study of cases of abiraterone discontinuation due to toxicity in pre-chemotherapy after 1 year's experience.
Topics: Abiraterone Acetate; Aged, 80 and over; Androstenes; Disease Progression; Docetaxel; Humans; Male; Middle Aged; Prostatic Neoplasms, Castration-Resistant; Safety-Based Drug Withdrawals; Taxoids; Time Factors; Treatment Outcome | 2017 |
Patient preferences for treatment of castration-resistant prostate cancer in Japan: a discrete-choice experiment.
Topics: Aged; Androstenes; Antineoplastic Agents; Docetaxel; Humans; Japan; Male; Patient Preference; Prostatic Neoplasms, Castration-Resistant; Radioisotopes; Radium; Taxoids | 2016 |
Comment on: "Modeling the Relationship between Exposure to Abiraterone and Prostate-Specific Antigen Dynamics in Patients with Metastatic Castration-Resistant Prostate Cancer".
Topics: Abiraterone Acetate; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Humans; Male; Neoplasm Metastasis; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Outcome | 2017 |
Author's Reply to Srinivas: "Modeling the Relationship Between Exposure to Abiraterone and Prostate-Specific Antigen Dynamics in Patients with Metastatic Castration-Resistant Prostate Cancer".
Topics: Abiraterone Acetate; Androstenes; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant | 2017 |
Efficacy of Therapies After Galeterone in Patients With Castration-resistant Prostate Cancer.
Topics: Aged; Androstadienes; Androstenes; Benzamides; Benzimidazoles; Drug Therapy; Humans; Kallikreins; Male; Middle Aged; Nitriles; Phenylthiohydantoin; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Survival Analysis; Treatment Outcome | 2017 |
An exploratory analysis of the association between levels of hormones implied in steroid biosynthesis and activity of abiraterone in patients with metastatic castration-resistant prostate cancer.
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Agents, Hormonal; Hormones; Humans; Male; Middle Aged; Neoplasm Metastasis; Predictive Value of Tests; Prognosis; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Steroids; Treatment Outcome | 2017 |
Prostate cancer: An abiraterone ultraresponsive phenotype.
Topics: Androstenes; Heterografts; Humans; Male; Phenotype; Prostatic Neoplasms, Castration-Resistant | 2017 |
The Role of the Neutrophil to Lymphocyte Ratio for Survival Outcomes in Patients with Metastatic Castration-Resistant Prostate Cancer Treated with Abiraterone.
Topics: Aged; Androstenes; Antineoplastic Agents; Humans; Kaplan-Meier Estimate; Leukocyte Count; Lymphocytes; Male; Middle Aged; Neoplasm Metastasis; Neutrophils; Prognosis; Proportional Hazards Models; Prostatic Neoplasms, Castration-Resistant; Treatment Outcome | 2017 |
Simultaneous quantitation of abiraterone, enzalutamide, N-desmethyl enzalutamide, and bicalutamide in human plasma by LC-MS/MS.
Topics: Androstenes; Anilides; Benzamides; Chromatography, Liquid; Humans; Male; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Spectrometry, Mass, Electrospray Ionization; Tosyl Compounds | 2017 |
[Concomitant use of abiraterone acetate and triptorelin in patients with castration-resistant prostate cancer].
Topics: Aged; Aged, 80 and over; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Humans; Male; Middle Aged; Neoplasm Metastasis; Prostatic Neoplasms, Castration-Resistant; Triptorelin Pamoate | 2016 |