Page last updated: 2024-09-04

abiraterone and Hormone-Dependent Neoplasms

abiraterone has been researched along with Hormone-Dependent Neoplasms in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (21.74)29.6817
2010's18 (78.26)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hartmann, RW; Hille, UE; Hu, Q; Jagusch, C; Yin, L1
Agarwal, N; Hahn, AW; Hale, P; Rathi, N1
Dowsett, M; Folkerd, E; Johnston, SR; Liccardi, G; Martin, LA; Nikitorowicz-Buniak, J; Pancholi, S; Ribas, R; Simigdala, N1
Kretschmer, A; Todenhöfer, T1
Halabi, S; Parelukar, WR; Rydzewska, L; Tierney, JF; Vale, CL1
Arlen, PM; Madan, RA1
Bossi, P; Civelli, E; Cortelazzi, B; Imbimbo, M; Licitra, L; Locati, LD; Perrone, F; Pilotti, S; Potepan, P; Quattrone, P; Rinaldi, G1
Aebersold, D; Attard, G; Cassoly, E; Clarke, NW; de Bono, JS; Dearnaley, DP; James, ND; Mason, MD; Matheson, D; Millman, R; Parker, CC; Parmar, MK; Ritchie, AW; Russell, JM; Schiavone, F; Spears, MR; Sydes, MR; Thalmann, G1
Aghai, A; Böttcher, R; Burger, H; de Morrée, ES; de Ridder, CM; de Wit, R; Gibson, AA; Mathijssen, RH; Sparreboom, A; van Soest, RJ; van Weerden, WM; Wiemer, EA1
Klein, EA; Raghavan, D1
Attard, G; Barrett, M; Clark, J; Cooper, CS; de Bono, JS; Dearnaley, D; Dowsett, M; Folkerd, E; Kaye, SB; Lee, G; Martins, V; Parker, C; Raynaud, F; Reid, AH; Settatree, S; Yap, TA1
Ang, JE; de Bono, JS; Olmos, D1
A'Hern, R; Attard, G; Carden, CP; Cooper, CS; Coumans, F; Cox, ME; de Bono, JS; Dearnaley, D; Hawche, G; Jameson, C; Kaye, SB; Levink, R; Molina, A; Moreira, J; Olmos, D; Oommen, NB; Parker, C; Reid, AH; Riisnaes, R; Sipkema, R; Swennenhuis, JF; Terstappen, LW; Thompson, E; Vickers, E1
A'Hern, R; Attard, G; de Bono, JS; Dearnaley, D; Dowsett, M; Folkerd, E; Kaye, SB; Kheoh, T; Lee, G; Maier, G; Messiou, C; Molife, LR; Molina, A; Olmos, D; Oommen, NB; Parker, C; Reid, AH; Sinha, R; Thompson, E1
Raghavan, D; Shepard, DR1
Chowdhury, S; Harper, P; Powles, T1
Miller, K1
Balk, SP; Cai, C1
Courtney, KD; Taplin, ME1
Bluemn, E; Edwards, J; Gurel, M; Hu, R; Isaacs, WB; Lu, C; Luo, J; Mostaghel, EA; Nelson, PS; Plymate, SR; Tannahill, C; Yegnasubramanian, S1
Albiges, L; Escudier, B; Fizazi, K; Loriot, Y; Massard, C1
Lewis, B; Pal, SK; Sartor, O1
Cheng, ML; Ryan, CJ1

Reviews

10 review(s) available for abiraterone and Hormone-Dependent Neoplasms

ArticleYear
Novel androgen axis systemic therapies for metastatic hormone-sensitive prostate cancer.
    Current opinion in urology, 2017, Volume: 27, Issue:6

    Topics: Androgen Antagonists; Androgens; Androstenes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Disease-Free Survival; Humans; Male; Neoplasms, Hormone-Dependent; Patient Selection; Prednisolone; Prednisone; Prostatic Neoplasms; Treatment Outcome

2017
Evidence Synthesis to Accelerate and Improve the Evaluation of Therapies for Metastatic Hormone-sensitive Prostate Cancer.
    European urology focus, 2019, Volume: 5, Issue:2

    Topics: Androgen Antagonists; Androstenes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Disease-Free Survival; Docetaxel; Humans; Male; Neoplasms, Hormone-Dependent; Prospective Studies; Prostatic Neoplasms; Randomized Controlled Trials as Topic

2019
Recent advances revolutionize treatment of metastatic prostate cancer.
    Future oncology (London, England), 2013, Volume: 9, Issue:8

    Topics: Androstenes; Androstenols; Antineoplastic Agents, Hormonal; Benzamides; Disease-Free Survival; Hormone Replacement Therapy; Humans; Immunotherapy; Male; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Tissue Extracts

2013
CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependence in castration-resistant prostate cancer.
    British journal of cancer, 2009, Mar-10, Volume: 100, Issue:5

    Topics: Androstenes; Androstenols; Antineoplastic Agents; Clinical Trials as Topic; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Male; Models, Biological; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase; Treatment Failure

2009
Innovations in the systemic therapy of prostate cancer.
    Nature reviews. Clinical oncology, 2010, Volume: 7, Issue:1

    Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Androstenes; Androstenols; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Cardiovascular Diseases; Chemotherapy, Adjuvant; Clinical Trials as Topic; Combined Modality Therapy; Disease Progression; Drug Delivery Systems; Drugs, Investigational; Humans; Male; Multicenter Studies as Topic; Neoadjuvant Therapy; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Osteoporosis; Prostatectomy; Prostatic Neoplasms; Salvage Therapy; Survival Analysis

2010
[Castration resistant prostate cancer 2011].
    Aktuelle Urologie, 2011, Volume: 42, Issue:2

    Topics: Androgen Antagonists; Androstenes; Androstenols; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Bone Neoplasms; Cancer Vaccines; Clinical Trials as Topic; Docetaxel; Drug Resistance, Neoplasm; Humans; Ketoconazole; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Steroid 17-alpha-Hydroxylase; Taxoids; Tissue Extracts

2011
Intratumoral androgen biosynthesis in prostate cancer pathogenesis and response to therapy.
    Endocrine-related cancer, 2011, Volume: 18, Issue:5

    Topics: Androgens; Androstenes; Androstenols; Enzyme Inhibitors; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen

2011
The evolving paradigm of second-line hormonal therapy options for castration-resistant prostate cancer.
    Current opinion in oncology, 2012, Volume: 24, Issue:3

    Topics: Androgen Antagonists; Androgens; Androstadienes; Androstenes; Androstenols; Antineoplastic Agents; Benzamides; Benzimidazoles; Clinical Trials as Topic; Drug Resistance, Neoplasm; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Steroid 17-alpha-Hydroxylase; Thiohydantoins

2012
Management of docetaxel failures in metastatic castrate-resistant prostate cancer.
    The Urologic clinics of North America, 2012, Volume: 39, Issue:4

    Topics: Androstenes; Androstenols; Antineoplastic Agents; Benzamides; Docetaxel; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Radium; Receptors, Androgen; Steroid 17-alpha-Hydroxylase; Taxoids; Treatment Failure

2012
Abiraterone acetate for the treatment of prostate cancer.
    Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:1

    Topics: Adenocarcinoma; Administration, Oral; Androstenes; Androstenols; Antineoplastic Agents; Castration; Disease Progression; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen

2013

Trials

3 trial(s) available for abiraterone and Hormone-Dependent Neoplasms

ArticleYear
Combining enzalutamide with abiraterone, prednisone, and androgen deprivation therapy in the STAMPEDE trial.
    European urology, 2014, Volume: 66, Issue:5

    Topics: Androgen Antagonists; Androstenes; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cytochrome P-450 Enzyme Inhibitors; Humans; Male; Neoplasms, Hormone-Dependent; Nitriles; Phenylthiohydantoin; Prednisone; Prostatic Neoplasms; Research Design; Steroid 17-alpha-Hydroxylase; Switzerland; Treatment Outcome; United Kingdom

2014
Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Oct-01, Volume: 26, Issue:28

    Topics: Adenocarcinoma; Administration, Oral; Aged; Aged, 80 and over; Androstenes; Androstenols; Castration; Disease Progression; Humans; Male; Middle Aged; Neoplasms, Hormone-Dependent; Prospective Studies; Prostatic Neoplasms; Treatment Outcome

2008
Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-10, Volume: 27, Issue:23

    Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Androgen Antagonists; Androstenes; Androstenols; Antineoplastic Agents, Hormonal; Disease Progression; Drug Administration Schedule; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasms, Hormone-Dependent; Prospective Studies; Prostate-Specific Antigen; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase; Testosterone

2009

Other Studies

10 other study(ies) available for abiraterone and Hormone-Dependent Neoplasms

ArticleYear
Isopropylidene substitution increases activity and selectivity of biphenylmethylene 4-pyridine type CYP17 inhibitors.
    Journal of medicinal chemistry, 2010, Jul-08, Volume: 53, Issue:13

    Topics: Antineoplastic Agents, Hormonal; Biphenyl Compounds; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Pyridines; Spectrometry, Mass, Electrospray Ionization; Steroid 17-alpha-Hydroxylase; Structure-Activity Relationship; Substrate Specificity

2010
Abiraterone shows alternate activity in models of endocrine resistant and sensitive disease.
    British journal of cancer, 2018, Volume: 119, Issue:3

    Topics: Androstenes; Apoptosis; Aromatase Inhibitors; Breast Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Mutation; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Receptors, Androgen; Signal Transduction; Tamoxifen

2018
Are There Still Patients with Metastatic Hormone-sensitive Prostate Cancer Who Should Be Treated with Androgen Deprivation Monotherapy?
    European urology focus, 2019, Volume: 5, Issue:2

    Topics: Aged; Aged, 80 and over; Androgen Antagonists; Androstenes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Disease-Free Survival; Docetaxel; Humans; Male; Middle Aged; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Quality of Life; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome; Tubulin Modulators

2019
Activity of abiraterone in rechallenging two AR-expressing salivary gland adenocarcinomas, resistant to androgen-deprivation therapy.
    Cancer biology & therapy, 2014, Jun-01, Volume: 15, Issue:6

    Topics: Adenocarcinoma; Adult; Androgen Antagonists; Androstenes; Androstenols; Anilides; Antineoplastic Agents, Hormonal; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Receptors, Androgen; Salivary Gland Neoplasms; Tosyl Compounds; Treatment Outcome; Triptorelin Pamoate

2014
Loss of SLCO1B3 drives taxane resistance in prostate cancer.
    British journal of cancer, 2016, 09-06, Volume: 115, Issue:6

    Topics: Adenocarcinoma; Androgens; Androstenes; Animals; Antineoplastic Agents, Phytogenic; Benzamides; Biological Transport; Cell Line, Tumor; Docetaxel; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Heterografts; Humans; Male; Mice, Nude; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Organic Anion Transporters, Sodium-Independent; Phenylthiohydantoin; Prostatic Neoplasms; RNA Interference; RNA, Small Interfering; Solute Carrier Organic Anion Transporter Family Member 1B3; Taxoids

2016
Prostate cancer: moving forward by reinventing the wheel...but this time it is round.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Oct-01, Volume: 26, Issue:28

    Topics: Androstenes; Androstenols; Castration; Clinical Trials as Topic; Disease Progression; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms

2008
Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer.
    Cancer research, 2009, Apr-01, Volume: 69, Issue:7

    Topics: Androstenes; Androstenols; Antigens, Neoplasm; Cell Adhesion Molecules; Epithelial Cell Adhesion Molecule; Gene Order; Humans; Immunomagnetic Separation; In Situ Hybridization, Fluorescence; Keratins; Male; Neoplasms, Hormone-Dependent; Neoplastic Cells, Circulating; Oncogene Proteins, Fusion; Prostatic Neoplasms; PTEN Phosphohydrolase; Receptors, Androgen; Trans-Activators; Transcriptional Regulator ERG

2009
Castration refractory prostate cancer: cinderella finally comes to the ball.
    Onkologie, 2010, Volume: 33, Issue:12

    Topics: Androstenes; Androstenols; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase III as Topic; Drug Resistance, Neoplasm; Drugs, Investigational; Humans; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Taxoids; Testosterone; Tissue Extracts

2010
Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer.
    Cancer research, 2012, Jul-15, Volume: 72, Issue:14

    Topics: Androstenes; Androstenols; Animals; Benzamides; Castration; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Ligands; Male; Mice; Neoplasms, Hormone-Dependent; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Protein Isoforms; Protein Structure, Tertiary; Receptors, Androgen; Signal Transduction; Transcription, Genetic; Transplantation, Heterologous; Ubiquitin-Conjugating Enzymes

2012
Novel and bone-targeted agents for CRPC.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23 Suppl 10

    Topics: Androgen Antagonists; Androstenes; Androstenols; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Bone Neoplasms; Clinical Trials, Phase III as Topic; Denosumab; Docetaxel; Humans; Ipilimumab; Male; Neoplasms, Hormone-Dependent; Orchiectomy; Prostate-Specific Antigen; Prostatic Neoplasms; Taxoids; Tissue Extracts; Tumor Microenvironment

2012