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abecarnil and Drug Withdrawal Symptoms

abecarnil has been researched along with Drug Withdrawal Symptoms in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's14 (87.50)18.2507
2000's2 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hönack, D; Löscher, W; Rundfeldt, C; Wlaź, P1
Emmett-Oglesby, MW; English, SA; Lytle, DA1
Schneider, HH; Stephens, DN; Steppuhn, KG; Turski, L1
Ebert, U; Hönack, D; Löscher, W; Rundfeldt, C1
Contarino, A; Giusti, P; Lipartiti, M; Natolino, F; Zanotti, A1
Galici, R; Pinna, G; Schneider, HH; Stephens, DN; Turski, L1
Anton, RF; Bianca, R; Kranzler, HR; McEvoy, JP; Moak, DH1
Ballenger, JC; Lydiard, RB; Rickels, K1
Bystritsky, A; Small, GW1
Aufdembrinke, B1
Argyropoulos, SV; Nutt, DJ1
Elliot, EE; White, JM1
Gatch, MB; Jung, ME; Lal, H; Wallis, CJ1
Hönack, D; Löscher, W1
Ballenger, JC; Cook, B; Garvey, M; Goodard, AW; Lydiard, B; McDonald, S; Noyes, R; Patin, J; Rickels, K; Woods, SW1
Crabbe, JC1

Reviews

1 review(s) available for abecarnil and Drug Withdrawal Symptoms

ArticleYear
The use of benzodiazepines in anxiety and other disorders.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9 Suppl 6

    Topics: Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Benzodiazepines; Buspirone; Carbolines; Humans; Mental Disorders; Receptors, GABA-A; Sleep Wake Disorders; Substance Withdrawal Syndrome

1999

Trials

5 trial(s) available for abecarnil and Drug Withdrawal Symptoms

ArticleYear
A double-blind comparison of abecarnil and diazepam in the treatment of uncomplicated alcohol withdrawal.
    Psychopharmacology, 1997, Volume: 131, Issue:2

    Topics: Adult; Alcoholism; Anti-Anxiety Agents; Carbolines; Diazepam; Double-Blind Method; Humans; Male; Middle Aged; Substance Withdrawal Syndrome

1997
A double-blind evaluation of the safety and efficacy of abecarnil, alprazolam, and placebo in outpatients with generalized anxiety disorder. Abecarnil Work Group.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 11

    Topics: Adolescent; Adult; Aged; Alprazolam; Ambulatory Care; Anti-Anxiety Agents; Anxiety Disorders; Carbolines; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Patient Dropouts; Placebos; Psychiatric Status Rating Scales; Substance Withdrawal Syndrome; Treatment Outcome

1997
Double-blind, placebo-controlled trial of two doses of abecarnil for geriatric anxiety.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 11

    Topics: Age Factors; Aged; Anti-Anxiety Agents; Anxiety Disorders; Carbolines; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Headache; Humans; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Severity of Illness Index; Sleep Initiation and Maintenance Disorders; Sleep Stages; Substance Withdrawal Syndrome; Treatment Outcome

1997
Abecarnil, a new beta-carboline, in the treatment of anxiety disorders.
    The British journal of psychiatry. Supplement, 1998, Issue:34

    Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Carbolines; Double-Blind Method; Female; Humans; Male; Middle Aged; Substance Withdrawal Syndrome; Treatment Outcome

1998
The first double-blind, placebo-controlled trial of a partial benzodiazepine agonist, abecarnil (ZK 112-119), in generalized anxiety disorder.
    Advances in biochemical psychopharmacology, 1992, Volume: 47

    Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Carbolines; Double-Blind Method; Female; Humans; Male; Psychiatric Status Rating Scales; Substance Withdrawal Syndrome

1992

Other Studies

10 other study(ies) available for abecarnil and Drug Withdrawal Symptoms

ArticleYear
Anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. Comparison of diazepam, bretazenil and abecarnil.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:2

    Topics: Animals; Anticonvulsants; Benzodiazepinones; Carbolines; Diazepam; Disease Models, Animal; Drug Tolerance; Male; Mice; Receptors, GABA-A; Seizures; Substance Withdrawal Syndrome

1995
Abecarnil used to treat benzodiazepine withdrawal.
    Psychopharmacology series, 1993, Volume: 11

    Topics: Animals; Anti-Anxiety Agents; Carbolines; Chlordiazepoxide; Cues; Discrimination Learning; Flumazenil; Male; Rats; Substance Withdrawal Syndrome

1993
Long-term treatment with abecarnil does not induce diazepam-like dependence in mice.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Carbolines; Diazepam; Electromyography; Male; Mice; Receptors, GABA-A; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders

1993
Long-term studies on anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. I. Comparison of diazepam, clonazepam, clobazam and abecarnil.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbolines; Clobazam; Clonazepam; Diazepam; Drug Tolerance; GABA-A Receptor Agonists; Ligands; Male; Mice; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders

1996
Abecarnil, a beta-carboline derivative, does not exhibit anticonvulsant tolerance or withdrawal effects in mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 354, Issue:5

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Bicuculline; Binding Sites; Carbolines; Convulsants; Diazepam; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mice; Seizures; Substance Withdrawal Syndrome

1996
Alprazolam dependence prevented by substituting with the beta-carboline abecarnil.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Mar-18, Volume: 94, Issue:6

    Topics: Alprazolam; Analysis of Variance; Animals; Anticonvulsants; Anxiety; Carbolines; Electroencephalography; Electromyography; Male; Mice; Mice, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1997
Long-term abecarnil administration produces tolerance and withdrawal signs in the rat.
    European journal of pharmacology, 2000, Apr-14, Volume: 394, Issue:2-3

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Body Temperature; Carbolines; Drug Tolerance; Electromyography; Flumazenil; GABA Modulators; Male; Motor Activity; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Telemetry

2000
Abecarnil and alprazolam reverse anxiety-like behaviors induced by ethanol withdrawal.
    Alcohol (Fayetteville, N.Y.), 2000, Volume: 21, Issue:2

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Carbolines; Discrimination Learning; Ethanol; Male; Pentylenetetrazole; Rats; Rats, Long-Evans; Self Administration; Substance Withdrawal Syndrome

2000
Withdrawal precipitation by benzodiazepine receptor antagonists in dogs chronically treated with diazepam or the novel anxiolytic and anticonvulsant beta-carboline abecarnil.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Carbolines; Diazepam; Dogs; Female; Flumazenil; GABA-A Receptor Antagonists; Oxazepam; Substance Withdrawal Syndrome

1992
Antagonism of ethanol withdrawal convulsions in Withdrawal Seizure Prone mice by diazepam and abecarnil.
    European journal of pharmacology, 1992, Oct-06, Volume: 221, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Carbolines; Diazepam; Ethanol; Female; Mice; Seizures; Substance Withdrawal Syndrome

1992