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abecarnil and Chemical Dependence

abecarnil has been researched along with Chemical Dependence in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Griffiths, RR; Mumford, GK; Rush, CR1
Ator, NA; Griffiths, RR; Sannerud, CA1
Löscher, W1
Schneider, HH; Stephens, DN; Steppuhn, KG; Turski, L1
Ebert, U; Hönack, D; Löscher, W; Rundfeldt, C1
Galici, R; Pinna, G; Schneider, HH; Stephens, DN; Turski, L1
Frey, HH; Hashem, A; Hönack, D; Löscher, W; Scherkl, R1

Reviews

1 review(s) available for abecarnil and Chemical Dependence

ArticleYear
Abecarnil shows reduced tolerance development and dependence potential in comparison to diazepam: animal studies.
    Psychopharmacology series, 1993, Volume: 11

    Topics: Animals; Anti-Anxiety Agents; Carbolines; Diazepam; Dogs; Drug Tolerance; Substance-Related Disorders

1993

Trials

1 trial(s) available for abecarnil and Chemical Dependence

ArticleYear
Abecarnil and alprazolam in humans: behavioral, subjective and reinforcing effects.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:2

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Behavior; Carbolines; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Male; Middle Aged; Reinforcement, Psychology; Substance-Related Disorders

1995

Other Studies

5 other study(ies) available for abecarnil and Chemical Dependence

ArticleYear
Behavioral pharmacology of abecarnil in baboons: reduced dependence and abuse potential.
    Psychopharmacology series, 1993, Volume: 11

    Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Carbolines; Papio; Substance-Related Disorders

1993
Long-term treatment with abecarnil does not induce diazepam-like dependence in mice.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Carbolines; Diazepam; Electromyography; Male; Mice; Receptors, GABA-A; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders

1993
Long-term studies on anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. I. Comparison of diazepam, clonazepam, clobazam and abecarnil.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbolines; Clobazam; Clonazepam; Diazepam; Drug Tolerance; GABA-A Receptor Agonists; Ligands; Male; Mice; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders

1996
Alprazolam dependence prevented by substituting with the beta-carboline abecarnil.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Mar-18, Volume: 94, Issue:6

    Topics: Alprazolam; Analysis of Variance; Animals; Anticonvulsants; Anxiety; Carbolines; Electroencephalography; Electromyography; Male; Mice; Mice, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1997
Pharmacokinetics, anticonvulsant efficacy and adverse effects of the beta-carboline abecarnil, a novel ligand for benzodiazepine receptors, after acute and chronic administration in dogs.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Blood Pressure; Carbolines; Dogs; Female; Flumazenil; Heart Rate; Male; Motor Activity; Receptors, GABA-A; Respiration; Substance-Related Disorders

1990