abecarnil has been researched along with Absence Seizure in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (92.31) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cook, JM; Cox, ED; Diaz-Arauzo, H; Harris, B; Huang, Q; Ma, C; McKernan, R; Reddy, MS; Skolnick, P | 1 |
| Hoffmann, K; Löscher, W; Potschka, H; Töllner, K; Twele, F | 1 |
| Hönack, D; Löscher, W; Rundfeldt, C; Wlaź, P | 1 |
| Hönack, D; Löscher, W | 1 |
| Akai, T; Nakada-Kometani, Y; Ozawa, M; Sugimachi, K; Yamaguchi, M | 1 |
| Schneider, HH; Stephens, DN; Steppuhn, KG; Turski, L | 1 |
| Biggio, G; Ghiani, CA; Motzo, C; Porceddu, ML; Serra, M | 1 |
| Hansen, HC; Jackson, HC; Judge, ME; Klitgaard, H; Kristiansen, M; Suzdak, PD; Swedberg, MD | 1 |
| Ebert, U; Hönack, D; Löscher, W; Rundfeldt, C | 1 |
| Contarino, A; Giusti, P; Lipartiti, M; Natolino, F; Zanotti, A | 2 |
| Crabbe, JC | 1 |
| Hönack, D; Löscher, W; Rundfeldt, C | 1 |
13 other study(ies) available for abecarnil and Absence Seizure
| Article | Year |
|---|---|
Synthesis and evaluation of analogues of the partial agonist 6-(propyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (6-PBC) and the full agonist 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (Zk 93423)
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Binding, Competitive; Carbolines; Cell Line; Cerebral Cortex; Drug Design; GABA Agonists; Humans; Male; Mice; Muscle Relaxation; Rats; Receptors, GABA-A; Recombinant Proteins; Seizures; Structure-Activity Relationship | 1998 |
The novel antiepileptic drug imepitoin compares favourably to other GABA-mimetic drugs in a seizure threshold model in mice and dogs.
Topics: Animals; Anticonvulsants; Carbolines; Dogs; Dose-Response Relationship, Drug; Drug Partial Agonism; Female; GABA-A Receptor Agonists; Imidazoles; Male; Mice; Pentylenetetrazole; Phenobarbital; Seizures | 2013 |
Anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. Comparison of diazepam, bretazenil and abecarnil.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Carbolines; Diazepam; Disease Models, Animal; Drug Tolerance; Male; Mice; Receptors, GABA-A; Seizures; Substance Withdrawal Syndrome | 1995 |
Kindling increases the sensitivity of rats to adverse effects of certain antiepileptic drugs.
Topics: Animals; Anticonvulsants; Ataxia; Behavior, Animal; Carbolines; Dose-Response Relationship, Drug; Female; Kindling, Neurologic; Motor Activity; Rats; Seizures; Stereotyped Behavior; Valproic Acid | 1995 |
Chronic pharmacological activities of the novel anxiolytic beta-carboline abecarnil in rats.
Topics: Animals; Anti-Anxiety Agents; Carbolines; Diazepam; Drinking Behavior; Male; Memory; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 1994 |
Long-term treatment with abecarnil does not induce diazepam-like dependence in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Carbolines; Diazepam; Electromyography; Male; Mice; Receptors, GABA-A; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 1993 |
Antagonism of isoniazid-induced convulsions by abecarnil in mice tolerant to diazepam.
Topics: Animals; Anticonvulsants; Benzodiazepines; Carbolines; Convulsants; Diazepam; Dose-Response Relationship, Drug; Drug Tolerance; GABA Modulators; Imidazoles; Isoniazid; Male; Mice; Seizures | 1995 |
Anticonvulsant profile of the imidazoquinazolines NNC 14-0185 and NNC 14-0189 in rats and mice.
Topics: Acoustic Stimulation; Amygdala; Animals; Anticonvulsants; Bicuculline; Carbolines; Clonazepam; Diazepam; Electroshock; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Kindling, Neurologic; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Pentylenetetrazole; Quinazolines; Rats; Rats, Wistar; Seizures | 1996 |
Long-term studies on anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. I. Comparison of diazepam, clonazepam, clobazam and abecarnil.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbolines; Clobazam; Clonazepam; Diazepam; Drug Tolerance; GABA-A Receptor Agonists; Ligands; Male; Mice; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 1996 |
Abecarnil, a beta-carboline derivative, does not exhibit anticonvulsant tolerance or withdrawal effects in mice.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Bicuculline; Binding Sites; Carbolines; Convulsants; Diazepam; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mice; Seizures; Substance Withdrawal Syndrome | 1996 |
Abecarnil enhances recovery from diazepam tolerance.
Topics: Animals; Anticonvulsants; Benzodiazepines; Bicuculline; Carbolines; Cell Membrane; Cerebral Cortex; Clonazepam; Diazepam; Drug Interactions; Drug Tolerance; Flumazenil; Imidazoles; Ligands; Male; Mice; Receptors, GABA-A; Seizures; Tritium | 1999 |
Antagonism of ethanol withdrawal convulsions in Withdrawal Seizure Prone mice by diazepam and abecarnil.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Carbolines; Diazepam; Ethanol; Female; Mice; Seizures; Substance Withdrawal Syndrome | 1992 |
Tolerance to anticonvulsant effects of the partial benzodiazepine receptor agonist abecarnil in kindled rats involves learning.
Topics: Animals; Anticonvulsants; Carbolines; Conditioning, Psychological; Drug Tolerance; Female; Kindling, Neurologic; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures | 1991 |