abacavir and Epilepsy--Complex-Partial

abacavir has been researched along with Epilepsy--Complex-Partial* in 1 studies

Other Studies

1 other study(ies) available for abacavir and Epilepsy--Complex-Partial

ArticleYear
Severe anemia secondary to a probable drug interaction between zidovudine and valproic acid.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, Mar-01, Volume: 38, Issue:5

    A 42-year-old man with human immunodeficiency virus (HIV) infection and a history of complex partial seizures developed severe anemia after the addition of valproic acid to his stable antiretroviral regimen of zidovudine, lamivudine, and abacavir. The inhibition of zidovudine glucuronidation by valproic acid and the resultant zidovudine hematologic toxicity is the proposed mechanism of the interaction.

    Topics: Anemia; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; Drug Interactions; Epilepsy, Complex Partial; HIV Infections; Humans; Lamivudine; Male; Valproic Acid; Zidovudine

2004