aa 861 and Pleurisy
aa 861 has been researched along with Pleurisy in 4 studies
2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone: structure given in first source
docebenone : A member of the class of benzoquinones that is p-benzoquinone in which the hydrogens are substituted by three methyl groups and a 12-hydroxydodeca-5,10-diyn-1-yl group.
Pleurisy: INFLAMMATION of PLEURA, the lining of the LUNG. When PARIETAL PLEURA is involved, there is pleuritic CHEST PAIN.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of leukotriene B4 (LTB4) in leukocyte infiltration in zymosan-induced rat pleurisy was investigated by studying the effects of 5-lipoxygenase inhibitors, T-0757 and AA-861, and a cyclooxygenase inhibitor, indomethacin, on leukocyte infiltration and LTB4 levels in the inflammatory exudate of rat pleurisy induced by intrapleural injection of zymosan (20 mg/rat)." | 7.69 | Involvement of leukotriene B4 in zymosan-induced rat pleurisy: inhibition of leukocyte infiltration by the 5-lipoxygenase inhibitor T-0757. ( Kikuchi, M; Naito, K; Tsuzurahara, K, 1995) |
| "The role of leukotriene B4 (LTB4) in leukocyte infiltration in zymosan-induced rat pleurisy was investigated by studying the effects of 5-lipoxygenase inhibitors, T-0757 and AA-861, and a cyclooxygenase inhibitor, indomethacin, on leukocyte infiltration and LTB4 levels in the inflammatory exudate of rat pleurisy induced by intrapleural injection of zymosan (20 mg/rat)." | 3.69 | Involvement of leukotriene B4 in zymosan-induced rat pleurisy: inhibition of leukocyte infiltration by the 5-lipoxygenase inhibitor T-0757. ( Kikuchi, M; Naito, K; Tsuzurahara, K, 1995) |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Ashida, Y | 2 |
| Saijo, T | 2 |
| Kuriki, H | 2 |
| Makino, H | 2 |
| Terao, S | 2 |
| Maki, Y | 2 |
| Kikuchi, M | 1 |
| Tsuzurahara, K | 1 |
| Naito, K | 1 |
| Ku, EC | 1 |
| Raychaudhuri, A | 1 |
| Ghai, G | 1 |
| Kimble, EF | 1 |
| Lee, WH | 1 |
| Colombo, C | 1 |
| Dotson, R | 1 |
| Oglesby, TD | 1 |
| Wasley, JW | 1 |
Other Studies
4 other studies available for aa 861 and Pleurisy
| Article | Year |
|---|---|
Pharmacological profile of AA-861, a 5-lipoxygenase inhibitor.
Topics: Animals; Arachidonate Lipoxygenases; Asthma; Benzoquinones; Edema; Female; Guinea Pigs; Histamine Re | 1983 |
Involvement of leukotriene B4 in zymosan-induced rat pleurisy: inhibition of leukocyte infiltration by the 5-lipoxygenase inhibitor T-0757.
Topics: Amides; Animals; Benzoquinones; Guinea Pigs; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase | 1995 |
Characterization of CGS 8515 as a selective 5-lipoxygenase inhibitor using in vitro and in vivo models.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Biotransfor | 1988 |
Role of leukotrienes in rat reversed passive Arthus pleurisy and the effect of AA-861, a 5-lipoxygenase inhibitor.
Topics: Animals; Arachidonate Lipoxygenases; Arthus Reaction; Benzoquinones; Biological Assay; Capillary Per | 1986 |