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aa 861 and Pleurisy

aa 861 has been researched along with Pleurisy in 4 studies

2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone: structure given in first source
docebenone : A member of the class of benzoquinones that is p-benzoquinone in which the hydrogens are substituted by three methyl groups and a 12-hydroxydodeca-5,10-diyn-1-yl group.

Pleurisy: INFLAMMATION of PLEURA, the lining of the LUNG. When PARIETAL PLEURA is involved, there is pleuritic CHEST PAIN.

Research Excerpts

ExcerptRelevanceReference
"The role of leukotriene B4 (LTB4) in leukocyte infiltration in zymosan-induced rat pleurisy was investigated by studying the effects of 5-lipoxygenase inhibitors, T-0757 and AA-861, and a cyclooxygenase inhibitor, indomethacin, on leukocyte infiltration and LTB4 levels in the inflammatory exudate of rat pleurisy induced by intrapleural injection of zymosan (20 mg/rat)."7.69Involvement of leukotriene B4 in zymosan-induced rat pleurisy: inhibition of leukocyte infiltration by the 5-lipoxygenase inhibitor T-0757. ( Kikuchi, M; Naito, K; Tsuzurahara, K, 1995)
"The role of leukotriene B4 (LTB4) in leukocyte infiltration in zymosan-induced rat pleurisy was investigated by studying the effects of 5-lipoxygenase inhibitors, T-0757 and AA-861, and a cyclooxygenase inhibitor, indomethacin, on leukocyte infiltration and LTB4 levels in the inflammatory exudate of rat pleurisy induced by intrapleural injection of zymosan (20 mg/rat)."3.69Involvement of leukotriene B4 in zymosan-induced rat pleurisy: inhibition of leukocyte infiltration by the 5-lipoxygenase inhibitor T-0757. ( Kikuchi, M; Naito, K; Tsuzurahara, K, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ashida, Y2
Saijo, T2
Kuriki, H2
Makino, H2
Terao, S2
Maki, Y2
Kikuchi, M1
Tsuzurahara, K1
Naito, K1
Ku, EC1
Raychaudhuri, A1
Ghai, G1
Kimble, EF1
Lee, WH1
Colombo, C1
Dotson, R1
Oglesby, TD1
Wasley, JW1

Other Studies

4 other studies available for aa 861 and Pleurisy

ArticleYear
Pharmacological profile of AA-861, a 5-lipoxygenase inhibitor.
    Prostaglandins, 1983, Volume: 26, Issue:6

    Topics: Animals; Arachidonate Lipoxygenases; Asthma; Benzoquinones; Edema; Female; Guinea Pigs; Histamine Re

1983
Involvement of leukotriene B4 in zymosan-induced rat pleurisy: inhibition of leukocyte infiltration by the 5-lipoxygenase inhibitor T-0757.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:9

    Topics: Amides; Animals; Benzoquinones; Guinea Pigs; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase

1995
Characterization of CGS 8515 as a selective 5-lipoxygenase inhibitor using in vitro and in vivo models.
    Biochimica et biophysica acta, 1988, Apr-15, Volume: 959, Issue:3

    Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Biotransfor

1988
Role of leukotrienes in rat reversed passive Arthus pleurisy and the effect of AA-861, a 5-lipoxygenase inhibitor.
    International archives of allergy and applied immunology, 1986, Volume: 79, Issue:1

    Topics: Animals; Arachidonate Lipoxygenases; Arthus Reaction; Benzoquinones; Biological Assay; Capillary Per

1986