Page last updated: 2024-10-21

aa 861 and Necrosis

aa 861 has been researched along with Necrosis in 7 studies

2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone: structure given in first source
docebenone : A member of the class of benzoquinones that is p-benzoquinone in which the hydrogens are substituted by three methyl groups and a 12-hydroxydodeca-5,10-diyn-1-yl group.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Pancreatitis was induced in rats by retrograde injection of 0."1.29Protective effect of AA-861 (5-lipoxygenase inhibitor) on experimental acute necrotizing pancreatitis in rats. ( Izumi, R; Kiriyama, M; Miyazaki, I, 1993)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's4 (57.14)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, L1
Liu, YR1
Gao, S1
Li, JF1
Li, SS1
Zhang, DD1
Liu, S1
Bai, L1
Zheng, SJ1
Duan, ZP1
Qi, M1
Chen, Y1
Gillis, RC1
Daley, BJ1
Enderson, BL1
Karlstad, MD1
Kiriyama, M1
Izumi, R1
Miyazaki, I1
Mizoguchi, Y3
Kawada, N2
Tsutsui, H1
Kobayashi, K3
Shiba, T1
Ikeda, M1
Hara, A1
Yoshida, H1
Kaneko, H1
Takeuchi, S1
Sakagami, Y2
Yamamoto, S2
Morisawa, S2
Seki, S1

Other Studies

7 other studies available for aa 861 and Necrosis

ArticleYear
Inhibition of 5-lipoxygenase pathway attenuates acute liver failure by inhibiting macrophage activation.
    Journal of immunology research, 2014, Volume: 2014

    Topics: Animals; Arachidonate 5-Lipoxygenase; Benzoquinones; Disease Models, Animal; Gene Expression; Lipopo

2014
Role of downstream metabolic processing of proinflammatory fatty acids by 5-lipoxygenase in HL-60 cell apoptosis.
    The Journal of trauma, 2003, Volume: 54, Issue:1

    Topics: Apoptosis; Arachidonate 5-Lipoxygenase; Benzoquinones; Cyclooxygenase Inhibitors; DNA Fragmentation;

2003
Protective effect of AA-861 (5-lipoxygenase inhibitor) on experimental acute necrotizing pancreatitis in rats.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1993, Volume: 13, Issue:3

    Topics: Acute Disease; Amylases; Animals; Benzoquinones; Lipase; Lipoxygenase Inhibitors; Male; Necrosis; Pa

1993
Network of cytokine and arachidonic acid cascade in acute hepatic failure.
    Gastroenterologia Japonica, 1993, Volume: 28 Suppl 4

    Topics: Animals; Arachidonic Acid; Benzoquinones; Cytokines; Gram-Positive Bacterial Infections; Kupffer Cel

1993
Mechanism of acute gastrointestinal mucosal damage in endotoxic shock and the effect of Fragmin.
    Seminars in thrombosis and hemostasis, 1990, Volume: 16 Suppl

    Topics: Acute Disease; Animals; Benzoquinones; Dogs; Gastric Mucosa; Hemorrhage; Heparin; Heparin, Low-Molec

1990
Changes in leukotrienes and prostaglandins in the liver tissue of rats in the experimental massive hepatic cell necrosis model.
    Prostaglandins, leukotrienes, and essential fatty acids, 1990, Volume: 40, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzoquinones; Bile; Dinoprostone; Kinetics; Leukotrienes; Li

1990
Protective effects of a leukotriene inhibitor in an experimental massive hepatic cell necrosis model.
    Gastroenterologia Japonica, 1988, Volume: 23, Issue:3

    Topics: Animals; Benzoquinones; Lipopolysaccharides; Lipoxygenase Inhibitors; Liver; Liver Diseases; Male; M

1988