aa 861 has been researched along with Muscle Contraction in 14 studies
2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone: structure given in first source
docebenone : A member of the class of benzoquinones that is p-benzoquinone in which the hydrogens are substituted by three methyl groups and a 12-hydroxydodeca-5,10-diyn-1-yl group.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levobupivacaine is a long-acting local anesthetic with a clinical profile similar to that of racemic bupivacaine but with a greater margin of safety." | 1.36 | The direct effect of levobupivacaine in isolated rat aorta involves lipoxygenase pathway activation and endothelial nitric oxide release. ( Choi, YS; Hah, YS; Hwang, EM; Jeong, YS; Lee, SH; Ok, SH; Park, JY; Shin, IW; Sohn, JT, 2010) |
| "Etodolac was found to have no effect on 5-lipoxygenase activity." | 1.29 | Effect of anti-inflammatory agent etodolac on antigen-induced contractions of the trachea and lung parenchyma of guinea pigs. ( Hamada, K; Inoue, K; Kimura, K; Shibata, Y; Ueda, F, 1994) |
| " Cimetidine shifted the dose-response curve for histamine to the right, but chlorpheniramine did not alter the response." | 1.27 | Mechanisms of histamine-induced relaxation in isolated monkey and dog coronary arteries. ( Toda, N, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ok, SH | 2 |
| Byon, HJ | 1 |
| Jin, H | 1 |
| Kim, HJ | 1 |
| Kim, W | 1 |
| Nam, IK | 1 |
| Eun, SY | 1 |
| Sohn, JT | 2 |
| Choi, YS | 1 |
| Jeong, YS | 1 |
| Shin, IW | 1 |
| Lee, SH | 1 |
| Park, JY | 1 |
| Hwang, EM | 1 |
| Hah, YS | 1 |
| Yamamoto, S | 1 |
| Yoshimoto, T | 1 |
| Furukawa, M | 1 |
| Horie, T | 1 |
| Watanabe-Kohno, S | 1 |
| Inoue, K | 1 |
| Hamada, K | 1 |
| Ueda, F | 1 |
| Shibata, Y | 1 |
| Kimura, K | 1 |
| Tudorić, N | 1 |
| Coon, RL | 1 |
| Bosnjak, ZJ | 1 |
| Shirahase, H | 1 |
| Kanda, M | 1 |
| Kurahashi, K | 1 |
| Nakamura, S | 1 |
| Stanke-Labesque, F | 1 |
| Hardy, G | 1 |
| Vergnaud, S | 1 |
| Devillier, P | 1 |
| Peoc'h, M | 1 |
| Randon, J | 1 |
| Bricca, G | 1 |
| Caron, F | 1 |
| Cracowski, JL | 1 |
| Bessard, G | 1 |
| Tashiro, K | 1 |
| Xie, Z | 1 |
| Ito, Y | 1 |
| Isogai, T | 1 |
| Taki, F | 1 |
| Suzuki, K | 1 |
| Takagi, K | 1 |
| Satake, T | 1 |
| Yamane, K | 1 |
| Kobayashi, T | 1 |
| Kobayashi, J | 1 |
| Hoshi, A | 1 |
| Kitamura, S | 2 |
| Kanamaru, K | 1 |
| Waga, S | 1 |
| Fujimoto, K | 1 |
| Itoh, H | 1 |
| Kubo, Y | 1 |
| Toda, N | 1 |
| Uchida, Y | 1 |
| Shimizu, K | 1 |
| Takaku, F | 1 |
14 other studies available for aa 861 and Muscle Contraction
| Article | Year |
|---|---|
Dexmedetomidine-induced contraction involves c-Jun NH2 -terminal kinase phosphorylation through activation of the 5-lipoxygenase pathway in the isolated endothelium-denuded rat aorta.
Topics: Animals; Aorta, Thoracic; Arachidonate 5-Lipoxygenase; Benzoquinones; Cyclooxygenase 2 Inhibitors; D | 2014 |
The direct effect of levobupivacaine in isolated rat aorta involves lipoxygenase pathway activation and endothelial nitric oxide release.
Topics: Anesthetics, Local; Animals; Aorta, Thoracic; Benzoquinones; Bupivacaine; Calcium; Dose-Response Rel | 2010 |
Arachidonate 5-lipoxygenase and its new inhibitors.
Topics: Animals; Arachidonate Lipoxygenases; Basophils; Benzoquinones; Cell Line; Flavones; Flavonoids; Guin | 1984 |
Effect of anti-inflammatory agent etodolac on antigen-induced contractions of the trachea and lung parenchyma of guinea pigs.
Topics: Animals; Asthma; Benzoquinones; Disease Models, Animal; Etodolac; Guinea Pigs; Immunization, Passive | 1994 |
Phosphoramidon modulates effects of the 5-lipoxygenase inhibition on anaphylactic contraction of the guinea pig trachea.
Topics: Anaphylaxis; Animals; Benzoquinones; Female; Glycopeptides; Guinea Pigs; In Vitro Techniques; Lipoxy | 1994 |
Endothelium-dependent relaxation followed by contraction mediated by NK(1) receptors in precontracted rabbit intrapulmonary arteries.
Topics: Animals; Benzamides; Benzoquinones; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; L | 2000 |
Involvement of cysteinyl leukotrienes in angiotensin II-induced contraction in isolated aortas from transgenic (mRen-2)27 rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Aorta; Arachidonate 5-Lipoxygenase; Benzoqui | 2002 |
Effects of PAF on excitatory neuro-effector transmission in dog airways.
Topics: Acetylcholine; Animals; Benzoquinones; Bronchi; Carbachol; Dogs; Electric Stimulation; Female; In Vi | 1992 |
Inhibitory effect of dietary administration of eicosapentaenoic acid on the contractions of guinea-pig tracheal smooth muscle induced by leukotriene C4 and D4.
Topics: Animals; Benzoquinones; Body Weight; Chromatography, High Pressure Liquid; Diet; Eicosapentaenoic Ac | 1991 |
Endogenous AA metabolites and their possible role in tracheal smooth muscle tone in guinea pigs.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Chromones; Dibenz(b,f)(1,4)oxazepine-10 | 1990 |
[Mechanisms of bronchoconstriction induced by anaphylaxis in sensitized guinea pigs].
Topics: Anaphylaxis; Animals; Benzoquinones; Bronchi; Guinea Pigs; Histamine Antagonists; Indomethacin; Leuk | 1989 |
Endothelium-dependent relaxation of human basilar arteries.
Topics: Acetylcholine; Adult; Aged; Basilar Artery; Benzoquinones; Calcimycin; Child; Child, Preschool; Dose | 1989 |
Mechanisms of histamine-induced relaxation in isolated monkey and dog coronary arteries.
Topics: Animals; Benzoquinones; Chlorpheniramine; Cimetidine; Coronary Vessels; Dogs; Female; Histamine; Ind | 1986 |
[Effects of various drugs on antigen-induced contractile responses in guinea pig tracheal and lung parenchymal strips].
Topics: Animals; Antigen-Antibody Reactions; Benzoquinones; Guinea Pigs; In Vitro Techniques; Lung; Methyser | 1985 |