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aa 861 and Inflammation

aa 861 has been researched along with Inflammation in 9 studies

2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone: structure given in first source
docebenone : A member of the class of benzoquinones that is p-benzoquinone in which the hydrogens are substituted by three methyl groups and a 12-hydroxydodeca-5,10-diyn-1-yl group.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
" Since exposure to ozone also caused neuronal M2 receptors to become dependent upon cyclooxygenase the effects of viral infection are likely to be due to inflammation."3.69Viral infection induces dependence of neuronal M2 muscarinic receptors on cyclooxygenase in guinea pig lung. ( Fryer, AD; Jacoby, DB; Kahn, RM; Okanlami, OA, 1996)
"Allergic inflammation was induced by injecting an antigen solution into an air pouch made on the dorsum of immunized rats with the antigen azobenzene-arsonate-conjugated acetyl bovine serum albumin."1.28Possible role for platelet-activating factor in neutrophil infiltration in allergic inflammation in rats. ( Hirasawa, N; Mue, S; Ohuchi, K; Omata, M; Sugidachi, A; Tsurufuji, S; Watanabe, M, 1990)
"Leukotriene B4 (LTB4) is a metabolite of arachidonic acid that has potent chemotactic activity for polymorphonuclear leukocytes (PMN)."1.27The role of leukotriene B4 in the genesis of oxygen toxicity in the lung. ( Ozawa, T; Satake, T; Sugiyama, S; Takagi, K; Taki, F; Taniguchi, H, 1986)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's3 (33.33)18.2507
2000's3 (33.33)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Musser, JH1
Kreft, AF1
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Mello, GC1
Desouza, IA1
Mariano, NS1
Ferreira, T1
Macedo, ML1
Antunes, E1
Gillis, RC1
Daley, BJ1
Enderson, BL1
Karlstad, MD1
Chung, SW1
Toriba, A1
Chung, HY1
Yu, BP1
Kameda, T1
Tang, N1
Kizu, R1
Hayakawa, K1
Kahn, RM1
Okanlami, OA1
Jacoby, DB1
Fryer, AD1
Watanabe, M1
Sugidachi, A1
Omata, M1
Hirasawa, N1
Mue, S1
Tsurufuji, S1
Ohuchi, K1
Maki, Y1
Ashida, Y1
Makino, H1
Saijo, T1
Kuriki, H1
Terao, S1
Taniguchi, H1
Taki, F1
Takagi, K1
Satake, T1
Sugiyama, S1
Ozawa, T1

Reviews

1 review available for aa 861 and Inflammation

ArticleYear
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.
    Journal of medicinal chemistry, 1992, Jul-10, Volume: 35, Issue:14

    Topics: Animals; Arachidonate 5-Lipoxygenase; Asthma; Eosinophils; Humans; Inflammation; Leukotriene Antagon

1992

Other Studies

8 other studies available for aa 861 and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Mechanisms involved in the rat peritoneal leukocyte migration induced by a Kunitz-type inhibitor isolated from Dimorphandra mollis seeds.
    Toxicon : official journal of the International Society on Toxinology, 2009, Mar-01, Volume: 53, Issue:3

    Topics: Analysis of Variance; Animals; Benzoquinones; Celecoxib; Cell Movement; Dexamethasone; Fabaceae; Ind

2009
Role of downstream metabolic processing of proinflammatory fatty acids by 5-lipoxygenase in HL-60 cell apoptosis.
    The Journal of trauma, 2003, Volume: 54, Issue:1

    Topics: Apoptosis; Arachidonate 5-Lipoxygenase; Benzoquinones; Cyclooxygenase Inhibitors; DNA Fragmentation;

2003
Activation of 5-lipoxygenase and NF-kappa B in the action of acenaphthenequinone by modulation of oxidative stress.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 101, Issue:1

    Topics: Acenaphthenes; Acetylcysteine; Antioxidants; Arachidonate 15-Lipoxygenase; Benzoquinones; Biotransfo

2008
Viral infection induces dependence of neuronal M2 muscarinic receptors on cyclooxygenase in guinea pig lung.
    The Journal of clinical investigation, 1996, Jul-15, Volume: 98, Issue:2

    Topics: Animals; Antibodies, Viral; Benzoquinones; Cells, Cultured; Cyclooxygenase Inhibitors; Electric Stim

1996
Possible role for platelet-activating factor in neutrophil infiltration in allergic inflammation in rats.
    International archives of allergy and applied immunology, 1990, Volume: 92, Issue:4

    Topics: Animals; Benzoquinones; Furans; Hypersensitivity; Immunization; Inflammation; Male; N-Formylmethioni

1990
Antiallergic activity of AA-861, a 5-lipoxygenase inhibitor.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1985, Volume: 15

    Topics: Animals; Arachidonate Lipoxygenases; Benzoquinones; Histamine H1 Antagonists; Hypersensitivity; Infl

1985
The role of leukotriene B4 in the genesis of oxygen toxicity in the lung.
    The American review of respiratory disease, 1986, Volume: 133, Issue:5

    Topics: Animals; Benzoquinones; Female; Inflammation; Leukotriene B4; Lung; Lung Diseases; Microsomes; NADPH

1986