aa 861 has been researched along with Hypersensitivity in 5 studies
2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone: structure given in first source
docebenone : A member of the class of benzoquinones that is p-benzoquinone in which the hydrogens are substituted by three methyl groups and a 12-hydroxydodeca-5,10-diyn-1-yl group.
Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone (AA-861), a selective 5-lipoxygenase inhibitor, on immunological or non-immunological release of slow reacting substance of anaphylaxis (SRS-A) and histamine and its effects on experimental asthma were investigated." | 3.67 | Effect of AA-861, a selective 5-lipoxygenase inhibitor, on models of allergy in several species. ( Kohno, SW; Nanbu, F; Negi, H; Ohata, K; Taira, M; Yamamura, H, 1988) |
| "Allergic inflammation was induced by injecting an antigen solution into an air pouch made on the dorsum of immunized rats with the antigen azobenzene-arsonate-conjugated acetyl bovine serum albumin." | 1.28 | Possible role for platelet-activating factor in neutrophil infiltration in allergic inflammation in rats. ( Hirasawa, N; Mue, S; Ohuchi, K; Omata, M; Sugidachi, A; Tsurufuji, S; Watanabe, M, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Watanabe, M | 2 |
| Arakida, Y | 1 |
| Tanabe, J | 1 |
| Sugidachi, A | 2 |
| Hirasawa, N | 2 |
| Mue, S | 2 |
| Ohuchi, K | 2 |
| Sakuma, Y | 1 |
| Katayama, S | 1 |
| Tsunoda, H | 1 |
| Abe, S | 1 |
| Yamatsu, I | 1 |
| Katayama, K | 1 |
| Omata, M | 1 |
| Tsurufuji, S | 1 |
| Yamamura, H | 1 |
| Taira, M | 1 |
| Negi, H | 1 |
| Nanbu, F | 1 |
| Kohno, SW | 1 |
| Ohata, K | 1 |
| Maki, Y | 1 |
| Ashida, Y | 1 |
| Makino, H | 1 |
| Saijo, T | 1 |
| Kuriki, H | 1 |
| Terao, S | 1 |
5 other studies available for aa 861 and Hypersensitivity
| Article | Year |
|---|---|
Pharmacological analysis of neutrophil chemotactic factor production by leucocytes and roles of PAF in allergic inflammation in rats.
Topics: Animals; Azepines; Benzoquinones; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relatio | 1994 |
Effects of the new 5-lipoxygenase inhibitor E6080 on leukotriene release in vitro.
Topics: Animals; Arachidonate 5-Lipoxygenase; Basophils; Benzoquinones; Dose-Response Relationship, Drug; Gu | 1992 |
Possible role for platelet-activating factor in neutrophil infiltration in allergic inflammation in rats.
Topics: Animals; Benzoquinones; Furans; Hypersensitivity; Immunization; Inflammation; Male; N-Formylmethioni | 1990 |
Effect of AA-861, a selective 5-lipoxygenase inhibitor, on models of allergy in several species.
Topics: Animals; Asthma; Benzoquinones; Calcimycin; Chromatography, High Pressure Liquid; Female; Guinea Pig | 1988 |
Antiallergic activity of AA-861, a 5-lipoxygenase inhibitor.
Topics: Animals; Arachidonate Lipoxygenases; Benzoquinones; Histamine H1 Antagonists; Hypersensitivity; Infl | 1985 |