aa 861 has been researched along with Disease Models, Animal in 10 studies
2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone: structure given in first source
docebenone : A member of the class of benzoquinones that is p-benzoquinone in which the hydrogens are substituted by three methyl groups and a 12-hydroxydodeca-5,10-diyn-1-yl group.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetic acid colitis was induced 24 hr before enzyme inhibition began." | 5.29 | Effects of cyclooxygenase and lipoxygenase inhibition on eicosanoids and healing of acetic acid colitis in rats. ( Guth, E; Guth, PH; LeDuc, LE; Reedy, T; Su, KC, 1993) |
| "We tried to produce a new ulcerative colitis model in rats by topical administration of sulfhydryl blockers." | 1.30 | New ulcerative colitis model induced by sulfhydryl blockers in rats and the effects of antiinflammatory drugs on the colitis. ( Sato, F; Satoh, H; Szabo, S; Takami, K, 1997) |
| "Etodolac was found to have no effect on 5-lipoxygenase activity." | 1.29 | Effect of anti-inflammatory agent etodolac on antigen-induced contractions of the trachea and lung parenchyma of guinea pigs. ( Hamada, K; Inoue, K; Kimura, K; Shibata, Y; Ueda, F, 1994) |
| "Acetic acid colitis was induced 24 hr before enzyme inhibition began." | 1.29 | Effects of cyclooxygenase and lipoxygenase inhibition on eicosanoids and healing of acetic acid colitis in rats. ( Guth, E; Guth, PH; LeDuc, LE; Reedy, T; Su, KC, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Li, L | 1 |
| Liu, YR | 1 |
| Gao, S | 1 |
| Li, JF | 1 |
| Li, SS | 1 |
| Zhang, DD | 1 |
| Liu, S | 1 |
| Bai, L | 1 |
| Zheng, SJ | 1 |
| Duan, ZP | 1 |
| Qi, M | 1 |
| Chen, Y | 1 |
| Reichel, CA | 1 |
| Rehberg, M | 1 |
| Lerchenberger, M | 1 |
| Berberich, N | 1 |
| Bihari, P | 1 |
| Khandoga, AG | 1 |
| Zahler, S | 1 |
| Krombach, F | 1 |
| Okubo, M | 1 |
| Yamanaka, H | 1 |
| Kobayashi, K | 1 |
| Noguchi, K | 1 |
| Inoue, K | 1 |
| Hamada, K | 1 |
| Ueda, F | 1 |
| Shibata, Y | 1 |
| Kimura, K | 1 |
| LeDuc, LE | 1 |
| Su, KC | 1 |
| Guth, E | 1 |
| Reedy, T | 1 |
| Guth, PH | 1 |
| Baskaya, MK | 1 |
| Hu, Y | 1 |
| Donaldson, D | 1 |
| Maley, M | 1 |
| Rao, AM | 1 |
| Prasad, MR | 1 |
| Dempsey, RJ | 1 |
| Satoh, H | 1 |
| Sato, F | 1 |
| Takami, K | 1 |
| Szabo, S | 1 |
| Danno, K | 1 |
| Toda, K | 1 |
| Ikai, K | 1 |
| Horio, T | 1 |
| Imamura, S | 1 |
10 other studies available for aa 861 and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Inhibition of 5-lipoxygenase pathway attenuates acute liver failure by inhibiting macrophage activation.
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzoquinones; Disease Models, Animal; Gene Expression; Lipopo | 2014 |
Ccl2 and Ccl3 mediate neutrophil recruitment via induction of protein synthesis and generation of lipid mediators.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Benzoquinones; Cells, Cultured; Chemokine C | 2009 |
Leukotriene synthases and the receptors induced by peripheral nerve injury in the spinal cord contribute to the generation of neuropathic pain.
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzoquinones; Chromones; Disease Models, Animal; Enzyme Inhib | 2010 |
Effect of anti-inflammatory agent etodolac on antigen-induced contractions of the trachea and lung parenchyma of guinea pigs.
Topics: Animals; Asthma; Benzoquinones; Disease Models, Animal; Etodolac; Guinea Pigs; Immunization, Passive | 1994 |
Effects of cyclooxygenase and lipoxygenase inhibition on eicosanoids and healing of acetic acid colitis in rats.
Topics: Acetates; Acetic Acid; Analysis of Variance; Animals; Benzoquinones; Colitis; Colon; Cyclooxygenase | 1993 |
Protective effect of the 5-lipoxygenase inhibitor AA-861 on cerebral edema after transient ischemia.
Topics: Animals; Benzoquinones; Brain Edema; Brain Ischemia; Disease Models, Animal; Dose-Response Relations | 1996 |
New ulcerative colitis model induced by sulfhydryl blockers in rats and the effects of antiinflammatory drugs on the colitis.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Benzoquinones; Colitis, | 1997 |
Ultraviolet radiation suppresses mouse-ear edema induced by topical application of arachidonic acid.
Topics: Administration, Topical; Animals; Arachidonic Acids; Benzoquinones; Cell Count; Disease Models, Anim | 1990 |