Page last updated: 2024-10-21

aa 861 and Cirrhosis, Liver

aa 861 has been researched along with Cirrhosis, Liver in 1 studies

2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone: structure given in first source
docebenone : A member of the class of benzoquinones that is p-benzoquinone in which the hydrogens are substituted by three methyl groups and a 12-hydroxydodeca-5,10-diyn-1-yl group.

Research Excerpts

ExcerptRelevanceReference
"In different groups of portally perfused control and cirrhotic rat livers, the following were analyzed: a portal perfusion pressure (PP) dose-response curve to LTD4; the effects on PP caused by either vehicle, the selective 5-lipoxygenase inhibitor AA-861, the selective Cys-LT1 receptor antagonist MK-571, or the dual Cys-LT1 and Cys-LT2 receptor antagonist BAY u9773; and immunohistochemistry for 5-lipoxygenase in liver sections of cirrhotic and control livers."1.315-lipoxygenase inhibition reduces intrahepatic vascular resistance of cirrhotic rat livers: a possible role of cysteinyl-leukotrienes. ( Bosch, J; Claria, J; García-Pagán, JC; Graupera, M; Massaguer, A; Rodés, J; Titos, E, 2002)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Graupera, M1
García-Pagán, JC1
Titos, E1
Claria, J1
Massaguer, A1
Bosch, J1
Rodés, J1

Other Studies

1 other study available for aa 861 and Cirrhosis, Liver

ArticleYear
5-lipoxygenase inhibition reduces intrahepatic vascular resistance of cirrhotic rat livers: a possible role of cysteinyl-leukotrienes.
    Gastroenterology, 2002, Volume: 122, Issue:2

    Topics: Animals; Arachidonate 5-Lipoxygenase; Benzoquinones; Carbon Tetrachloride; Cysteine; Leukotriene Ant

2002