aa 861 has been researched along with Brain Swelling in 6 studies
2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone: structure given in first source
docebenone : A member of the class of benzoquinones that is p-benzoquinone in which the hydrogens are substituted by three methyl groups and a 12-hydroxydodeca-5,10-diyn-1-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute cerebral ischemia was produced in rats by injection of arachidonic acid (AA) into the internal carotid artery." | 7.68 | Protective effects of benidipine on arachidonic acid-induced acute cerebral ischemia in rats. ( Karasawa, A; Kubo, K; Sano, J; Shirakura, S, 1992) |
| "Acute cerebral ischemia was produced in rats by injection of arachidonic acid (AA) into the internal carotid artery." | 3.68 | Protective effects of benidipine on arachidonic acid-induced acute cerebral ischemia in rats. ( Karasawa, A; Kubo, K; Sano, J; Shirakura, S, 1992) |
| "Forebrain ischemia was induced by 4-vessel occlusion." | 1.29 | LTC4/LTB4 alterations in rat forebrain ischemia and reperfusion and effects of AA-861, CV-3988. ( Kimura, J; Namura, Y; Shio, H, 1994) |
| "Cerebral ischemia was accompanied by cerebral edema early after reperfusion." | 1.27 | Brain eicosanoid levels in spontaneously hypertensive rats after ischemia with reperfusion: leukotriene C4 as a possible cause of cerebral edema. ( Inamura, K; Kanda, Y; Kaseki, H; Katayama, Y; Minamisawa, H; Shimizu, J; Shiratori, T; Terashi, A; Yoshino, Y, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Namura, Y | 1 |
| Shio, H | 1 |
| Kimura, J | 1 |
| Yamasaki, Y | 1 |
| Shozuhara, H | 1 |
| Onodera, H | 1 |
| Kogure, K | 1 |
| Baskaya, MK | 1 |
| Hu, Y | 1 |
| Donaldson, D | 1 |
| Maley, M | 1 |
| Rao, AM | 1 |
| Prasad, MR | 1 |
| Dempsey, RJ | 1 |
| Shirakura, S | 1 |
| Sano, J | 1 |
| Karasawa, A | 1 |
| Kubo, K | 1 |
| Mabe, H | 1 |
| Nagai, H | 1 |
| Suzuka, T | 1 |
| Minamisawa, H | 1 |
| Terashi, A | 1 |
| Katayama, Y | 1 |
| Kanda, Y | 1 |
| Shimizu, J | 1 |
| Shiratori, T | 1 |
| Inamura, K | 1 |
| Kaseki, H | 1 |
| Yoshino, Y | 1 |
6 other studies available for aa 861 and Brain Swelling
| Article | Year |
|---|---|
LTC4/LTB4 alterations in rat forebrain ischemia and reperfusion and effects of AA-861, CV-3988.
Topics: Animals; Benzoquinones; Brain Edema; Brain Ischemia; Injections, Intraperitoneal; Leukotriene B4; Le | 1994 |
Blocking of interleukin-1 activity is a beneficial approach to ischemia brain edema formation.
Topics: Animals; Benzoquinones; Brain Edema; Brain Ischemia; Caudate Nucleus; Cerebral Cortex; Cerebral Infa | 1994 |
Protective effect of the 5-lipoxygenase inhibitor AA-861 on cerebral edema after transient ischemia.
Topics: Animals; Benzoquinones; Brain Edema; Brain Ischemia; Disease Models, Animal; Dose-Response Relations | 1996 |
Protective effects of benidipine on arachidonic acid-induced acute cerebral ischemia in rats.
Topics: Animals; Arachidonic Acid; Benzoquinones; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Calcium | 1992 |
Role of brain tissue leukotriene in brain oedema following cerebral ischaemia: effect of a 5-lipoxygenase inhibitor, AA-861.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Body Water; Brain Chemistry; Brain Edem | 1990 |
Brain eicosanoid levels in spontaneously hypertensive rats after ischemia with reperfusion: leukotriene C4 as a possible cause of cerebral edema.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzoquinones; Body Water; Brain; Brain Edema; Cerebrovascula | 1988 |