aa 861 has been researched along with Brain Ischemia in 6 studies
2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone: structure given in first source
docebenone : A member of the class of benzoquinones that is p-benzoquinone in which the hydrogens are substituted by three methyl groups and a 12-hydroxydodeca-5,10-diyn-1-yl group.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute cerebral ischemia was produced in rats by injection of arachidonic acid (AA) into the internal carotid artery." | 7.68 | Protective effects of benidipine on arachidonic acid-induced acute cerebral ischemia in rats. ( Karasawa, A; Kubo, K; Sano, J; Shirakura, S, 1992) |
| "Acute cerebral ischemia was produced in rats by injection of arachidonic acid (AA) into the internal carotid artery." | 3.68 | Protective effects of benidipine on arachidonic acid-induced acute cerebral ischemia in rats. ( Karasawa, A; Kubo, K; Sano, J; Shirakura, S, 1992) |
| "Forebrain ischemia was induced by 4-vessel occlusion." | 1.29 | LTC4/LTB4 alterations in rat forebrain ischemia and reperfusion and effects of AA-861, CV-3988. ( Kimura, J; Namura, Y; Shio, H, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, ZJ | 1 |
| Liang, CL | 1 |
| Li, GM | 1 |
| Yu, CY | 1 |
| Yin, M | 1 |
| Namura, Y | 1 |
| Shio, H | 1 |
| Kimura, J | 1 |
| Yamasaki, Y | 1 |
| Shozuhara, H | 1 |
| Onodera, H | 1 |
| Kogure, K | 1 |
| Baskaya, MK | 1 |
| Hu, Y | 1 |
| Donaldson, D | 1 |
| Maley, M | 1 |
| Rao, AM | 1 |
| Prasad, MR | 1 |
| Dempsey, RJ | 1 |
| Shirakura, S | 1 |
| Sano, J | 1 |
| Karasawa, A | 1 |
| Kubo, K | 1 |
| Mabe, H | 1 |
| Nagai, H | 1 |
| Suzuka, T | 1 |
6 other studies available for aa 861 and Brain Ischemia
| Article | Year |
|---|---|
Neuroprotective effects of arachidonic acid against oxidative stress on rat hippocampal slices.
Topics: Animals; Arachidonic Acid; Benzhydryl Compounds; Benzoquinones; Brain Ischemia; Catalase; Cyclohexim | 2006 |
LTC4/LTB4 alterations in rat forebrain ischemia and reperfusion and effects of AA-861, CV-3988.
Topics: Animals; Benzoquinones; Brain Edema; Brain Ischemia; Injections, Intraperitoneal; Leukotriene B4; Le | 1994 |
Blocking of interleukin-1 activity is a beneficial approach to ischemia brain edema formation.
Topics: Animals; Benzoquinones; Brain Edema; Brain Ischemia; Caudate Nucleus; Cerebral Cortex; Cerebral Infa | 1994 |
Protective effect of the 5-lipoxygenase inhibitor AA-861 on cerebral edema after transient ischemia.
Topics: Animals; Benzoquinones; Brain Edema; Brain Ischemia; Disease Models, Animal; Dose-Response Relations | 1996 |
Protective effects of benidipine on arachidonic acid-induced acute cerebral ischemia in rats.
Topics: Animals; Arachidonic Acid; Benzoquinones; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Calcium | 1992 |
Role of brain tissue leukotriene in brain oedema following cerebral ischaemia: effect of a 5-lipoxygenase inhibitor, AA-861.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Body Water; Brain Chemistry; Brain Edem | 1990 |