Page last updated: 2024-09-03

a 68930 and Disease Models, Animal

a 68930 has been researched along with Disease Models, Animal in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's4 (44.44)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Cao, JY; Li, ZL; Liu, BC; Liu, H; Yang, Y; Zhou, LT1
Bian, Z; He, F; He, Q; Jiang, W; Li, M; Liu, J; Sun, T; Wang, X; Zhu, L1
Hamann, M; Lange, N; Richter, A; Shashidharan, P1
Kohsaka, H; Matsushita, S; Miyasaka, N; Nakano, K; Nakashioya, H; Watanabe, N1
Chen, WF; Huang, CB; Huang, LT; Lai, MC; Wang, CL; Wu, CL; Yang, CH; Yang, SN1
Inagaki, M; Ishiguro, A; Kaga, M1
Collu, M; D'Aquila, PS; Gessa, GL; Pani, L; Serra, G1

Trials

1 trial(s) available for a 68930 and Disease Models, Animal

ArticleYear
Dopamine D1 receptor agonist A-68930 inhibits NLRP3 inflammasome activation and protects rats from spinal cord injury-induced acute lung injury.
    Spinal cord, 2016, Volume: 54, Issue:11

    Topics: Acute Lung Injury; Animals; Capillary Permeability; Chromans; Cytokines; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; NLR Family, Pyrin Domain-Containing 3 Protein; Organ Size; Peroxidase; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Time Factors

2016

Other Studies

8 other study(ies) available for a 68930 and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Dopamine D1 receptor agonist A68930 attenuates acute kidney injury by inhibiting NLRP3 inflammasome activation.
    Journal of pharmacological sciences, 2020, Volume: 143, Issue:3

    Topics: Acute Kidney Injury; Animals; Chromans; Disease Models, Animal; Down-Regulation; Inflammasomes; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Kidney; Male; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Receptors, Dopamine D1; Reperfusion Injury; Tumor Necrosis Factor-alpha

2020
Behavioural and pharmacological examinations in a transgenic mouse model of early-onset torsion dystonia.
    Pharmacology, biochemistry, and behavior, 2011, Volume: 97, Issue:4

    Topics: Amphetamines; Animals; Anxiety; Behavior, Animal; Carbidopa; Chromans; Disease Models, Animal; Dystonia; Levodopa; Locomotion; Mice; Mice, Transgenic; Quinpirole; Raclopride

2011
Therapeutic effect of D1-like dopamine receptor antagonist on collagen-induced arthritis of mice.
    Modern rheumatology, 2011, Volume: 21, Issue:3

    Topics: Animals; Arthritis, Experimental; Benzazepines; Cell Differentiation; Cells, Cultured; Chromans; Cytokines; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Gene Expression; Macrophages; Male; Mice; Mice, Inbred DBA; Osteoclasts; Radiography; Receptors, Dopamine D1

2011
Impaired SynGAP expression and long-term spatial learning and memory in hippocampal CA1 area from rats previously exposed to perinatal hypoxia-induced insults: beneficial effects of A68930.
    Neuroscience letters, 2004, Nov-16, Volume: 371, Issue:1

    Topics: Animals; Asphyxia Neonatorum; Chromans; Disease Models, Animal; Dopamine Agonists; GTPase-Activating Proteins; Hippocampus; Humans; Hypoxia, Brain; Infant, Newborn; Maze Learning; Memory; Rats; Rats, Sprague-Dawley; Space Perception

2004
Stereotypic circling behavior in mice with vestibular dysfunction: asymmetrical effects of intrastriatal microinjection of a dopamine agonist.
    The International journal of neuroscience, 2007, Volume: 117, Issue:7

    Topics: Animals; Chromans; Disease Models, Animal; Dopamine; Dopamine Agonists; Functional Laterality; Gait Disorders, Neurologic; Humans; Male; Mice; Mice, Inbred ICR; Mice, Mutant Strains; Microinjections; Motor Activity; Neostriatum; Statistics, Nonparametric; Stereotyped Behavior; Stereotypic Movement Disorder; Vestibular Diseases; Vestibule, Labyrinth

2007
Antidepressant-like effect of selective dopamine D1 receptor agonists in the behavioural despair animal model of depression.
    European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Benzazepines; Chromans; Depression; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Imipramine; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Stereoisomerism

1994