a-192621 has been researched along with Uveal-Neoplasms* in 1 studies
1 other study(ies) available for a-192621 and Uveal-Neoplasms
Article | Year |
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Endothelin signaling promotes melanoma tumorigenesis driven by constitutively active GNAQ.
The G-protein-coupled receptor, endothelin receptor B (EDNRB), is an important regulator of melanocyte survival and proliferation. It acts by stimulating downstream heterotrimeric G proteins, such as Gα Topics: Animals; Carcinogenesis; Dermis; Endothelins; GTP-Binding Protein alpha Subunits, Gq-G11; Lung Neoplasms; Melanocytes; Melanoma; Meningeal Neoplasms; Mice, Knockout; Phenotype; Pyrrolidines; Receptor, Endothelin B; RNA, Untranslated; Signal Transduction; Skin Neoplasms; Uveal Neoplasms | 2020 |