Harringtonine has been researched along with Hemoglobinuria--Paroxysmal* in 1 studies
1 other study(ies) available for Harringtonine and Hemoglobinuria--Paroxysmal
| Article | Year |
|---|---|
[Preliminary study of DA or HA regimen chemotherapy for the treatment of refractory and relapsed paroxysmal nocturnal hemoglobinuria].
To observe the efficacy and side effect of DA/HA regimen chemotherapy for the treatment of refractory and relapsed paroxysmal nocturnal hemoglobinuria (PNH).. Eight patients with refractory and relapsed PNH were treated with DA/HA regimen chemotherapy. Three patients were treated with DA (DNR 40 mg/d, i.v.drip, the first and the second day; 20 mg/d, i.v.drip, the third day; Ara-C 100 mg/d, i.v.drip, for 5 days) and 5 patients with HA (HHT 2 - 3 mg/d, i.v.drip, for 5 days; Ara-C 100 mg/d, i.v.drip, for 5 days).. All the 8 patients responded well: the PNH clone was diminished in five patients. Hemolysis was remitted in 6 cases. Five patients showed improvement in hematological parameters. The dosage of corticosteroid was decreased in all of them. No serious side effect was revealed.. DA/HA regimen chemotherapy was safe and effective for refractory and relapsed PNH patients. Topics: Adolescent; Adult; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Glycosylphosphatidylinositols; Harringtonines; Hemoglobinuria, Paroxysmal; Humans; Male | 2004 |