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9-anthroic acid and Cystic Fibrosis

9-anthroic acid has been researched along with Cystic Fibrosis in 2 studies

9-anthroic acid: RN given refers to unlabeled parent cpd; chloride channel blocker; do not confuse with c-ANCA (anti-neutrophil cytoplasmic antibodies) which is frequently abbreviated as ANCA
9-anthroic acid : An anthroic acid carrying the carboxy substituent at position 9.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research Excerpts

ExcerptRelevanceReference
" Epithelial cells were isolated from human nasal polyps, cultured for 5-7 days, and used to test the effect of anthracene 9-carboxylate (9-AC), known to inhibit Cl- conductance across the epithelial membrane, on the incorporation and desaturation of [1-14C]linoleic acid (C18:2,n-6) in experiments of up to 4 h duration."3.68The chloride channel blocker anthracene 9-carboxylate inhibits fatty acid incorporation into phospholipid in cultured human airway epithelial cells. ( Brown, NE; Clandinin, MT; Kang, JX; Labrecque, PA; Man, SF, 1992)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kang, JX1
Man, SF1
Brown, NE1
Labrecque, PA1
Clandinin, MT1
Welsh, MJ1

Other Studies

2 other studies available for 9-anthroic acid and Cystic Fibrosis

ArticleYear
The chloride channel blocker anthracene 9-carboxylate inhibits fatty acid incorporation into phospholipid in cultured human airway epithelial cells.
    The Biochemical journal, 1992, Aug-01, Volume: 285 ( Pt 3)

    Topics: Amiloride; Anthracenes; Cells, Cultured; Chloride Channels; Chlorides; Cystic Fibrosis; Electric Con

1992
An apical-membrane chloride channel in human tracheal epithelium.
    Science (New York, N.Y.), 1986, Jun-27, Volume: 232, Issue:4758

    Topics: Anthracenes; Cell Membrane; Chlorides; Cystic Fibrosis; Epithelium; Ion Channels; Isoproterenol; Tra

1986