Page last updated: 2024-08-25

9-aminocamptothecin and Colorectal Cancer

9-aminocamptothecin has been researched along with Colorectal Cancer in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (85.71)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abbruzzese, JL; Arbuck, SG; Ballard, WP; Bradof, JE; Diaz-Canton, E; Graham, S; Pazdur, R; Winn, R1
Berkery, R; Harrison, J; Kelsen, DP; Kemeny, NE; Saltz, LB; Tong, W1
Eisenhauer, EA; Feld, R; Firby, PS; Goldberg, RA; Manzo, J; Michael, M; Moore, MJ; Oza, AM; Siu, LL; Thiessen, JJ; Wainman, N1
Punt, CJ1
Beijnen, JH; Bult, A; Herben, VM; Hillebrand, MJ; ten Bokkel Huinink, WW; van Gijn, R1
Blanke, CD; Rothenberg, ML1
Goldberg, RM; Hatfield, AK; Knost, JA; Krook, JE; Kugler, J; Mahoney, MR; Pitot, HC; Sargent, DJ1

Reviews

2 review(s) available for 9-aminocamptothecin and Colorectal Cancer

ArticleYear
New drugs in the treatment of colorectal carcinoma.
    Cancer, 1998, Aug-15, Volume: 83, Issue:4

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Quinazolines; Tegafur; Thiophenes; Topotecan; Trimetrexate; Uracil

1998
Topoisomerase I inhibitors in the treatment of colorectal cancer.
    Seminars in oncology, 1999, Volume: 26, Issue:6

    Topics: Animals; Antineoplastic Agents; Camptothecin; Clinical Trials as Topic; Colorectal Neoplasms; Enzyme Inhibitors; Humans; Irinotecan; Topoisomerase I Inhibitors; Topotecan

1999

Trials

4 trial(s) available for 9-aminocamptothecin and Colorectal Cancer

ArticleYear
Phase II trial of 9-aminocamptothecin administered as a 72-hour continuous infusion in metastatic colorectal carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Humans; Infusion Pumps; Infusions, Intravenous; Male; Middle Aged

1997
9-Aminocamptothecin by 72-hour continuous intravenous infusion is inactive in the treatment of patients with 5-fluorouracil-refractory colorectal carcinoma.
    Cancer, 1997, Nov-01, Volume: 80, Issue:9

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents; Camptothecin; Colorectal Neoplasms; Drug Resistance, Neoplasm; Female; Fluorouracil; Humans; Infusions, Intravenous; Middle Aged; Neoplasm Metastasis; Neutropenia; Thrombocytopenia; Treatment Outcome

1997
Phase I and pharmacologic study of 9-aminocamptothecin colloidal dispersion formulation given as a 24-hour continuous infusion weekly times four every 5 weeks.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Area Under Curve; Camptothecin; Chromatography, High Pressure Liquid; Colloids; Colorectal Neoplasms; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Regression Analysis; Salvage Therapy

1998
A North Central Cancer Treatment Group Phase II trial of 9-aminocamptothecin in previously untreated patients with measurable metastatic colorectal carcinoma.
    Cancer, 2000, Oct-15, Volume: 89, Issue:8

    Topics: Adult; Aged; Antineoplastic Agents; Camptothecin; Colorectal Neoplasms; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Survival Analysis; Time Factors

2000

Other Studies

1 other study(ies) available for 9-aminocamptothecin and Colorectal Cancer

ArticleYear
High-performance liquid chromatographic analysis of the investigational anticancer drug 9-aminocamptothecin, as the lactone form and as the total of the lactone and the hydroxycarboxylate forms, in micro-volumes of human plasma.
    Journal of pharmaceutical and biomedical analysis, 1998, Volume: 17, Issue:8

    Topics: Aged; Antineoplastic Agents; Camptothecin; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Drug Stability; Humans; Lactones; Reproducibility of Results

1998