9,10-dimethyl-1,2-benzanthracene has been researched along with Genetic Predisposition in 66 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 9 (13.64) | 18.2507 |
2000's | 40 (60.61) | 29.6817 |
2010's | 17 (25.76) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Balmain, A; Del Rosario, R; Harris, S; Kandyba, E; Reeves, MQ | 1 |
Balaiya, V; Johnson, LK; Koster, MI; Lakshmanachetty, S | 1 |
Samuelson, DJ; Sanders, J | 1 |
Blanco, MA; Bronson, RT; Chakrabarti, R; Chekmareva, M; Guo, F; Haffty, BG; Hua, Y; Kang, Y; Lu, X; Shen, M; Smith, HA; Wan, L; Wei, Y; Wu, H; Xing, Y; Yuan, M; Yuan, S | 1 |
Brady, M; Brennan-Crispi, DM; Hossain, C; Mahoney, MG; Riobo, NA; Sahu, J | 1 |
Järvinen, TA; Laitinen, AM; May, U; Nieminen, K; Prince, S; Uusitalo-Järvinen, H; Vähätupa, M | 1 |
Fujiwara, K; Ikeda, M; Inazawa, J; Nagase, H; Ozaki, T; Ozaki, Y; Soma, M; Terui, T | 1 |
Bornschein, RL; Gear, R; Govindarajah, V; Ho, SM; Leung, YK; Medvedovic, M; Ying, J | 1 |
Balmain, A; Del Rosario, R; Ginzinger, D; Halliwill, KD; Kang, HC; Quigley, DA | 1 |
Asai, M; Asai, N; Enomoto, A; Kato, T; Mii, S; Murakumo, Y; Nagino, M; Shiraki, Y; Sunagawa, M; Takahashi, M | 1 |
Han, L; Hang, H; He, W; Hopkins, KM; Hu, Z; Lieberman, HB; Liu, Y; Yang, L; Yang, X; Zhang, C; Zhao, Y | 1 |
Adamovic, T; Jacob, HJ; McAllister, D; Rowe, JJ; Sugg, SL; Wang, T | 1 |
Balajee, AS; Bhagat, G; Fang, H; Hei, TK; Lin, C; Shao, G; Wang, C; Wen, G; Zhang, Y; Zhao, Y | 1 |
Hao, L; McDonald, JD; Pasquali, M; Sidell, N | 1 |
Benito, C; Borràs, M; Castellana, B; Manils, J; Morán-Salvador, E; Ortega, S; Parra, D; Sancho, S; Soler, C; Tarancón, G; Vázquez-Villoldo, N; Viña-Vilaseca, A | 1 |
Bahassi, el M; Boivin, GP; Kuiper, R; Robbins, SB; Stambrook, PJ; van Steeg, H; Yin, M | 1 |
Furth, PA; Miermont, AM; Parrish, AR | 1 |
Cabrera, WH; Dragani, TA; Galvan, A; Ibañez, OM; Mancuso, M; Milani, S; Pazzaglia, S; Ribeiro, OG; Saran, A; Vorraro, F; Zolin, A | 1 |
Adamovic, D; Adamovic, T; Jacob, HJ; Lazar, J; McAllister, D; Moreno, C; Rowe, JJ; Sugg, SL; Wang, T | 1 |
Gould, MN; Haag, JD; Meilahn, AL; Remfert, JL; Samuelson, DJ; Veillet, AL | 1 |
Gould, MN; Haag, JD; Mau, B; Samuelson, DJ; Sharma, D; Smits, BM; Woditschka, S | 1 |
Desai, R; Gao, YR; Handelsman, DJ; Jimenez, M; Simanainen, U; Walters, KA; Watson, G | 1 |
Devapatla, B; Samuelson, DJ; Sanders, J | 1 |
Fukamachi, K; Han, BS; Maeda, M; Ohnishi, T; Takasuka, N; Tsuda, H; Yamasaki, T | 1 |
Chan, FL; Chen, ZY; Cheung, SY; Choi, HL; Huang, Y; James, AE | 1 |
Kannan, S; Kirtane, BM; Mansukhani, NP; Mulherkar, R; Naresh, KN; Ramchandani, A | 1 |
Gould, MN; Haag, JD; Kolman, BD; Lan, H; Monson, DM; Samuelson, DJ; Shultz, MA | 1 |
Curtin, GM; Doolittle, DJ; Goodman, JI; Watson, RE | 1 |
Covelli, V; Di Majo, V; Mancuso, M; Pazzaglia, S; Rebessi, S; Saran, A; Tanori, M | 1 |
Glick, A; Hennings, H; Michael, E; Smith, L; Vijayachandra, K; Woodworth, CD; Yuspa, SH | 1 |
Fukamachi, K; Han, BS; Kim, CK; Matsuda, E; Matsuoka, Y; Takasuka, N; Tsuda, H; Yamasaki, T | 1 |
Atkinson, MJ; Covelli, V; Di Majo, V; Hahn, H; Mancuso, M; Merola, P; Pazzaglia, S; Rebessi, S; Saran, A; Tanori, M | 1 |
Cleveland, JL; Guo, Y; O'Brien, TG | 1 |
Attardi, LD; Bronson, RT; Horner, JS; Ihrie, RA; Marques, MR | 1 |
Beems, RB; de Vries, A; Jacks, T; Jonkers, J; Olive, KP; Schaap, MM; Speksnijder, EN; Tuveson, DA; van den Berg, J; van Steeg, H; Wijnhoven, SW; Zwart, E | 1 |
Brooks, SC; Chen, J; Lu, S; Santner, SJ; Shen, K; Wang, Y; Wang, YA | 1 |
Angel, JM; Benavides, F; Conti, CJ; Flores, M; Fuchs-Young, R; Gomez, G; Lambertz, I; Richie, ER; Venables-Griffith, A | 1 |
Denning, MF; Gerber, L; Gilliam, AC; Guo, H; Miao, H; Singh, J; Wang, B | 1 |
Badger, TM; Eason, RR; Frank, JA; Korourian, S; Simmen, FA; Simmen, RC; Till, SR | 1 |
Laes, JF; Piessevaux, G; Quan, X; Rivière, M; Stieber, D; Szpirer, C; Szpirer, J | 1 |
Fujiwara, K; Igarashi, J; Irahara, N; Kimura, M; Nagase, H | 1 |
Bustos, T; Fischer, SM; Hu, Y; Liu, B; Park, E; Shen, J; Xia, X; Zhu, F | 1 |
Buchmann, A; Karcier, Z; Schmid, B; Schwarz, M; Strathmann, J | 1 |
Chiappetta, G; Costinean, S; Croce, CM; De Martino, I; Fedele, M; Fusco, A; Iuliano, R; Kusewitt, DF; Oberyszyn, TM; Palmieri, D; Server, IN; Visone, R | 1 |
Elmets, CA; Long, JA; Lucas, AP; Naseemuddin, M; Nasti, TH; Xu, H; Yusuf, N | 1 |
Crist, K; Jia, D; LaRegina, M; Lu, Y; Lubet, R; Wang, Y; Wen, W; Yao, R; You, M; Zhang, Z | 1 |
Berg, RJ; Capel, PJ; de Gruijl, FR; de Vries, A; Dortant, PM; Hofhuis, FM; van Kreijl, CF; van Oostrom, CT; van Steeg, H; Verbeek, SJ; Wester, PW | 1 |
Glick, AB; Hennings, H; Krsmanovic, LS; Lowry, DT; Sly, LM; Yuspa, SH | 1 |
Dove, WF; Gould, MN; Haag, JD; Lindstrom, MJ; Mattes, EM; Moser, AR | 1 |
Alexander, DL; Buters, JT; Doehmer, J; Gonzalez, FJ; Jefcoate, CR; Pineau, T; Richter, T; Sakai, S; Savas, U; Ward, JM | 1 |
Beems, RB; Berg, RJ; Bootsma, D; de Boer, J; de Gruijl, FR; de Wit, J; Garssen, J; Hoeijmakers, JH; van der Horst, GT; van Kreijl, CF; van Oostrum, CT; van Steeg, H; Weeda, G | 1 |
Bowden, GT; Broome Powell, M; Gause, PR; Gregus, J; Hyman, P; Lluria-Prevatt, M; Nagle, R | 1 |
Hibshoosh, H; Santella, RM; Slosberg, ED; Wang, L; Weinstein, IB; Xing, WQ; Yao, Y; Zhang, YJ | 1 |
Benavides, F; Conti, CJ; Klingelberger, EA; Stern, MC | 1 |
Benavides, F; Coghlan, LG; Conti, CJ; DiGiovanni, J; Glasscock, E; Stern, MC | 1 |
Biozzi, G; Covelli, V; Doria, G; Mouton, D; Neveu, T; Pazzaglia, S; Rebessi, S; Saran, A | 1 |
Bolon, I; Nichols, A; Vassalli, JD; Wohlwend, A; Zhou, HM | 1 |
Asamoto, M; Naito, A; Ochiya, T; Ota, T; Sekiya, T; Terada, M; Toriyama-Baba, H; Tsuda, H | 1 |
Kool, HJ; Mullenders, LH; Slater, R; van Zeeland, AA; Vrieling, H; Wijnhoven, SW | 1 |
Berns, A; Krimpenfort, P; Loonstra, A; Mooi, WJ; Quon, KC | 1 |
Aguirre, AJ; Bardeesy, N; Carrasco, D; Castrillon, DH; DePinho, RA; Horner, JW; Lee, KH; Sharpless, NE; Wu, EA | 1 |
Liu, AX; Liu, JP; Prendergast, GC; Rane, N | 1 |
Coleman, CS; Guo, Y; Megosh, LC; O'Brien, TG; Pegg, AE; Sawicki, JA | 1 |
Hirai, K; Ochiya, T; Saito, I; Sakamoto, H; Sasaki, H; Takeshita, F; Terada, M; Toriyama-Baba, H; Yamamoto, H; Yoshida, T | 1 |
Gould, MN; Zhang, R | 1 |
Gill, TJ; Kunz, HW; Melhem, MF | 1 |
1 review(s) available for 9,10-dimethyl-1,2-benzanthracene and Genetic Predisposition
Article | Year |
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Genetic regulation of mammary carcinogenesis in the rat by susceptibility and suppressor genes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Carcinoma; Cell Differentiation; Chimera; Crosses, Genetic; DNA Damage; Epithelium; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Graft Survival; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Phenotype; Rats; Rats, Inbred F344; Rats, Inbred WF; Transplantation, Heterotopic; Tumor Cells, Cultured | 1991 |
65 other study(ies) available for 9,10-dimethyl-1,2-benzanthracene and Genetic Predisposition
Article | Year |
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Multicolour lineage tracing reveals clonal dynamics of squamous carcinoma evolution from initiation to metastasis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Lineage; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Clonal Evolution; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Genetic Predisposition to Disease; Male; Mice, Transgenic; Mutation; Neoplasms, Experimental; Phenotype; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Burden | 2018 |
TRP63/TP63 loss accelerates skin tumorigenesis through activation of Wnt/β-catenin signaling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Mice, Knockout; Mice, Nude; Phosphoproteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Trans-Activators; Transcription Factors; Tumor Burden; Tumor Suppressor Proteins; Wnt Signaling Pathway | 2018 |
Significant overlap between human genome-wide association-study nominated breast cancer risk alleles and rat mammary cancer susceptibility loci.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Breast Neoplasms; Chromosome Mapping; Estradiol; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Genomics; Humans; Mammary Neoplasms, Animal; Polymorphism, Single Nucleotide; Rats; Rats, Inbred WF; Rats, Inbred WKY; Rats, Wistar; Risk; Selenoproteins | 2014 |
MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cell Transformation, Viral; Endonucleases; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; HEK293 Cells; Humans; Mammary Glands, Animal; Mammary Tumor Virus, Mouse; Medroxyprogesterone Acetate; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neoplasm Invasiveness; Neoplastic Stem Cells; Nuclear Proteins; Phenotype; Protein Binding; RNA Interference; RNA-Binding Proteins; Time Factors; Transfection; Tumor Cells, Cultured | 2014 |
Crosstalk between Desmoglein 2 and Patched 1 accelerates chemical-induced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma in Situ; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Dermis; Desmoglein 2; Epidermis; Gene Knock-In Techniques; Genes, Reporter; Genetic Predisposition to Disease; Genotype; Hair Follicle; Hedgehog Proteins; Hyperplasia; Keratinocytes; Mice; Mice, Transgenic; Papilloma; Patched Receptors; Patched-1 Receptor; Receptors, Cell Surface; Signal Transduction; Skin Neoplasms; Stromal Cells; Tetradecanoylphorbol Acetate; Time Factors | 2015 |
Resistance of R-Ras knockout mice to skin tumour induction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Proliferation; Dermis; Genetic Association Studies; Genetic Predisposition to Disease; Mice, Inbred C57BL; Mice, Knockout; Papilloma; ras Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2015 |
The oncogenic role of GASC1 in chemically induced mouse skin cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Cell Line, Tumor; Cell Survival; Female; Genetic Association Studies; Genetic Predisposition to Disease; Jumonji Domain-Containing Histone Demethylases; Male; Mice, Inbred C57BL; Mice, Knockout; Oncogenes; Papilloma; Skin Neoplasms; Tumor Burden | 2015 |
In utero exposure of rats to high-fat diets perturbs gene expression profiles and cancer susceptibility of prepubertal mammary glands.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Diet, High-Fat; Female; Gene Expression Profiling; Genetic Predisposition to Disease; Mammary Neoplasms, Experimental; Pregnancy; Rats; Rats, Sprague-Dawley; Sexual Maturation | 2016 |
Panx3 links body mass index and tumorigenesis in a genetically heterogeneous mouse model of carcinogen-induced cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Mass Index; Carcinogenesis; Carcinogens; Connexins; Crosses, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Genetic Predisposition to Disease; Humans; Inflammation; Lipid Metabolism; Male; Mice; Mice, Inbred Strains; Quantitative Trait Loci; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
Suppression of skin tumorigenesis in CD109-deficient mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; DNA Damage; Genes, ras; Genetic Predisposition to Disease; Keratinocytes; Mice, Knockout; Mutation; Neoplasm Proteins; NF-E2-Related Factor 2; Papilloma; Phenotype; Phosphorylation; Signal Transduction; Skin Neoplasms; Smad2 Protein; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta1 | 2016 |
Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cell Transformation, Neoplastic; DNA Damage; Gene Deletion; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Keratinocytes; Mice; Mutagens; Skin | 2008 |
Genetic mapping of mammary tumor traits to rat chromosome 10 using a novel panel of consomic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromosome Mapping; Crosses, Genetic; Female; Genetic Predisposition to Disease; Male; Mammary Neoplasms, Experimental; Neoplasms, Multiple Primary; Phenotype; Quantitative Trait Loci; Rats; Rats, Inbred BN; Rats, Inbred Dahl | 2008 |
TGFBI deficiency predisposes mice to spontaneous tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromosome Aberrations; Cyclic AMP Response Element-Binding Protein; Cyclin D1; Female; G1 Phase; Genes, bcl-1; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Promoter Regions, Genetic; RNA, Messenger; S Phase; Transforming Growth Factor beta1; Up-Regulation | 2009 |
Carcinogenic effects in a phenylketonuria mouse model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Carcinogens; Cytochrome P-450 CYP1B1; Female; Genetic Predisposition to Disease; Homozygote; Male; Mice; Neoplasms; Phenylacetates; Phenylketonurias | 2009 |
Increased Susceptibility to Skin Carcinogenesis in TREX2 Knockout Mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Apoptosis; Carcinogens; Carcinoma; Cells, Cultured; Embryo, Mammalian; Exodeoxyribonucleases; Female; Genetic Predisposition to Disease; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Specificity; Skin Neoplasms; Tissue Distribution | 2009 |
Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; cdc25 Phosphatases; Checkpoint Kinase 2; Female; Fibroblasts; Gene Deletion; Genetic Predisposition to Disease; Genotype; Immunohistochemistry; Male; Mice; Neoplasms; Phosphorylation; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases; Risk Factors; Sex Factors; Time Factors | 2009 |
Role of ERalpha in the differential response of Stat5a loss in susceptibility to mammary preneoplasia and DMBA-induced carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinogens; Disease Models, Animal; DNA Primers; Estrogen Receptor alpha; Genetic Predisposition to Disease; Immunohistochemistry; Mammary Neoplasms, Experimental; Mice; Precancerous Conditions; STAT5 Transcription Factor | 2010 |
Genetic heterogeneity of inflammatory response and skin tumorigenesis in phenotypically selected mouse lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Genetic Drift; Genetic Heterogeneity; Genetic Predisposition to Disease; Genome-Wide Association Study; Inflammation; Mice; Neutrophil Infiltration; Papilloma; Phenotype; Polymorphism, Single Nucleotide; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
Identification of novel carcinogen-mediated mammary tumor susceptibility loci in the rat using the chromosome substitution technique.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chromosome Mapping; Female; Genetic Predisposition to Disease; Mammary Neoplasms, Experimental; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Rats | 2010 |
Mcs5c: a mammary carcinoma susceptibility locus located in a gene desert that associates with tenascin C expression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Congenic; Blotting, Western; Carcinogens; Comparative Genomic Hybridization; Disease Susceptibility; Female; Genetic Predisposition to Disease; Mammary Neoplasms, Experimental; Phenotype; Quantitative Trait Loci; Rats; Rats, Inbred WF; Rats, Inbred WKY; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tenascin | 2011 |
The non-protein coding breast cancer susceptibility locus Mcs5a acts in a non-mammary cell-autonomous fashion through the immune system and modulates T-cell homeostasis and functions.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Breast Neoplasms; CD4-Positive T-Lymphocytes; CD8 Antigens; Cytokines; Epithelial Cells; Female; Genetic Loci; Genetic Predisposition to Disease; Homeostasis; L-Selectin; Mammary Neoplasms, Experimental; Methylnitrosourea; NK Cell Lectin-Like Receptor Subfamily B; Rats; Rats, Inbred WKY; Receptors, Antigen, T-Cell; T-Lymphocytes; Th1 Cells; Th2 Cells | 2011 |
Androgen resistance in female mice increases susceptibility to DMBA-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androgens; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Epithelial Cells; Female; Genetic Predisposition to Disease; Gonadotropins, Pituitary; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Androgen; Testosterone | 2012 |
Genetically determined inflammatory-response related cytokine and chemokine transcript profiles between mammary carcinoma resistant and susceptible rat strains.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Chemokines; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Inflammation; Mammary Neoplasms, Experimental; Rats; Receptors, Chemokine; RNA, Messenger | 2012 |
Inhibitory effects of 17beta-estradiol and 4-n-octylphenol on 7,12-dimethylbenz[a]anthracene-induced mammary tumor development in human c-Ha-ras proto-oncogene transgenic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Genetically Modified; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Estradiol; Female; Gene Transfer Techniques; Genes, ras; Genetic Predisposition to Disease; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Phenols; Proto-Oncogene Mas; Rats; Tumor Cells, Cultured | 2002 |
Spontaneous mammary tumors in aging Noble rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age of Onset; Animals; Carcinoma; Diethylstilbestrol; Drug Implants; Estradiol; Female; Fibroadenoma; Genetic Predisposition to Disease; Incidence; Male; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Metastasis; Neoplasm Transplantation; Ovariectomy; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Rodent Diseases; Species Specificity; Testosterone | 2003 |
Expression of enhancing factor/phospholipase A2 in skin results in abnormal epidermis and increased sensitivity to chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abnormalities, Multiple; Animals; Carcinogens; Carcinoma, Squamous Cell; Epidermis; Fibrosarcoma; Genetic Predisposition to Disease; Genotype; Group II Phospholipases A2; Humans; Keratins; Mice; Mice, Transgenic; Neoplasms, Basal Cell; Papilloma; Phenotype; Phospholipases A; Promoter Regions, Genetic; Recombinant Fusion Proteins; Skin; Skin Neoplasms; Tail; Tetradecanoylphorbol Acetate; Transgenes; Vibrissae | 2003 |
Physical evidence of Mcs5, a QTL controlling mammary carcinoma susceptibility, in congenic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Congenic; Female; Genetic Predisposition to Disease; Heterozygote; Mammary Neoplasms, Experimental; Quantitative Trait Loci; Rats; Rats, Inbred WKY | 2003 |
Progressive alterations in global and GC-rich DNA methylation during tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Carcinogens; Cytosine; DNA Methylation; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Guanosine; Mice; Mice, Inbred SENCAR; Polymerase Chain Reaction; Recovery of Function; Skin Neoplasms; Smoke; Tars | 2003 |
Only a subset of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin papillomas are promotable by benzoyl peroxide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Carcinogens; Cocarcinogenesis; DNA Primers; Drug Resistance, Neoplasm; Female; Genes, ras; Genetic Predisposition to Disease; Male; Mice; Mutation; Papilloma; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Strain-dependent differences in malignant conversion of mouse skin tumors is an inherent property of the epidermal keratinocyte.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Disease Progression; Epidermis; Genetic Predisposition to Disease; Humans; Infant, Newborn; Keratinocytes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred SENCAR; Mice, Nude; Oncogene Proteins, Viral; Papilloma; Papillomaviridae; Papillomavirus E7 Proteins; Repressor Proteins; Skin Neoplasms; Species Specificity | 2004 |
Possible enhancing effects of atrazine and nonylphenol on 7,12-dimethylbenz[a]anthracene-induced mammary tumor development in human c-Ha-ras proto-oncogene transgenic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animal Feed; Animals; Animals, Genetically Modified; Atrazine; Biological Assay; Carcinogens; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Endocrine System; Female; Genes, ras; Genetic Predisposition to Disease; Herbicides; Humans; Male; Mammary Neoplasms, Animal; Phenols; Proto-Oncogene Mas; Rats; Risk Assessment | 2004 |
Modulation of patched-associated susceptibility to radiation induced tumorigenesis by genetic background.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Allelic Imbalance; Animals; Carcinogens; Carcinoma, Basal Cell; Female; Genetic Predisposition to Disease; Inbreeding; Intracellular Signaling Peptides and Proteins; Loss of Heterozygosity; Male; Membrane Proteins; Mice; Neoplasms, Radiation-Induced; Patched Receptors; Patched-1 Receptor; Proteins; Receptors, Cell Surface; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Haploinsufficiency for odc modifies mouse skin tumor susceptibility.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biogenic Polyamines; Carcinogens; Cocarcinogenesis; Enzyme Induction; Female; Genetic Predisposition to Disease; Haploidy; Male; Mice; Mice, Inbred C57BL; Ornithine Decarboxylase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2005 |
Mice lacking the p53/p63 target gene Perp are resistant to papilloma development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Adhesion; Cell Differentiation; Cell Growth Processes; Female; Gene Silencing; Genes, p53; Genetic Predisposition to Disease; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Papilloma; Phosphoproteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trans-Activators | 2005 |
Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Female; Genes, p53; Genetic Predisposition to Disease; Humans; Inbreeding; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Transgenic; Milk Proteins; Point Mutation; Pregnancy; Recombinases | 2005 |
Atm-haploinsufficiency enhances susceptibility to carcinogen-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms; Carcinogens; Cell Cycle Proteins; DNA-Binding Proteins; Environmental Pollutants; Female; Genetic Predisposition to Disease; Heterozygote; Mammary Neoplasms, Animal; Mice; Protein Serine-Threonine Kinases; Risk Factors; Signal Transduction; Survival Analysis; Tumor Suppressor Proteins | 2006 |
Differential susceptibility to chemically induced thymic lymphomas in SENCARB and SSIN inbred mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Flow Cytometry; Genetic Predisposition to Disease; Lymphoma; Methylnitrosourea; Mice; Mice, Inbred AKR; Mice, Inbred SENCAR; Mice, Inbred Strains; Species Specificity; Thymus Neoplasms | 2006 |
Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Growth Processes; Cell Transformation, Neoplastic; Enzyme Activation; Ephrin-A1; Female; Genetic Predisposition to Disease; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Receptor, EphA2; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Tumor-protective and tumor-promoting actions of dietary whey proteins in an N-methyl-N-nitrosourea model of rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Caseins; Cell Differentiation; Disease Models, Animal; Female; Genetic Predisposition to Disease; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Milk Proteins; Pregnancy; Prenatal Exposure Delayed Effects; Proliferating Cell Nuclear Antigen; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Whey Proteins | 2006 |
Isolation of two regions on rat chromosomes 5 and 18 affecting mammary cancer susceptibility.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Congenic; Carcinogens; Chromosome Mapping; Chromosomes; Crosses, Genetic; Female; Genetic Predisposition to Disease; Genotype; Mammary Neoplasms, Experimental; Quantitative Trait Loci; Quantitative Trait, Heritable; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley | 2007 |
New chemically induced skin tumour susceptibility loci identified in a mouse backcross between FVB and dominant resistant PWK.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromosome Mapping; Crosses, Genetic; Drug Resistance; Female; Genes, Dominant; Genetic Linkage; Genetic Predisposition to Disease; Genotype; Male; Mice; Mice, Inbred Strains; Neoplasms, Second Primary; Papilloma; Quantitative Trait Loci; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Base Sequence; Carcinogens; Carcinoma; Cocarcinogenesis; Female; Genes, ras; Genetic Predisposition to Disease; I-kappa B Kinase; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutation; Neovascularization, Pathologic; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2007 |
Differential selection for B-raf and Ha-ras mutated liver tumors in mice with high and low susceptibility to hepatocarcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Genes, ras; Genetic Predisposition to Disease; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mutation; Proto-Oncogene Proteins B-raf; Species Specificity | 2008 |
Hmga1 null mice are less susceptible to chemically induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Genetic Predisposition to Disease; HMGA Proteins; Keratinocytes; Mice; Mice, Knockout; Papilloma; Proto-Oncogene Proteins c-fos; rab GTP-Binding Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Protective role of Toll-like receptor 4 during the initiation stage of cutaneous chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Line, Tumor; Cell Proliferation; Cytoprotection; Dermatitis, Contact; Female; Genetic Predisposition to Disease; Interleukin-12; Interleukin-23; Mice; Mice, Inbred C3H; Mice, Knockout; Neovascularization, Pathologic; Skin Neoplasms; Toll-Like Receptor 4 | 2008 |
Enhanced susceptibility to chemical induction of ovarian tumors in mice with a germ line p53 mutation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Genetic Predisposition to Disease; Germ-Line Mutation; Humans; Mice; Mice, Transgenic; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Tumor Suppressor Protein p53 | 2008 |
Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cells, Cultured; DNA Repair; DNA-Binding Proteins; Eye Neoplasms; Gene Deletion; Gene Targeting; Genetic Predisposition to Disease; Humans; Mice; Mice, Inbred C57BL; Neoplasms, Radiation-Induced; Radiation Tolerance; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein | 1995 |
FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Cell; Drug Resistance; Female; Genetic Predisposition to Disease; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1993 |
ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Crosses, Genetic; Ethylnitrosourea; Female; Genes, APC; Genetic Predisposition to Disease; Hyperplasia; Male; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Metaplasia; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Point Mutation | 1993 |
Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carcinogens; Cells, Cultured; Chimera; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Female; Fibroblasts; Gene Expression Regulation, Enzymologic; Genetic Predisposition to Disease; Genomic Library; Lung; Lymphoma; Mice; Mice, Knockout; Neoplasms, Experimental; Organ Specificity; Polychlorinated Dibenzodioxins; Restriction Mapping; Stem Cells | 1999 |
Mouse model for the DNA repair/basal transcription disorder trichothiodystrophy reveals cancer predisposition.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Cockayne Syndrome; Disease Models, Animal; DNA Helicases; DNA Repair; DNA-Binding Proteins; Fibroblasts; Gene Targeting; Genetic Predisposition to Disease; Growth Disorders; Hair Diseases; Humans; Hyperplasia; Ichthyosis; Mice; Mice, Inbred C57BL; Neoplastic Syndromes, Hereditary; Point Mutation; Proteins; Radiation Tolerance; Skin; Skin Neoplasms; Transcription Factor TFIIH; Transcription Factors; Transcription Factors, TFII; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group D Protein | 1999 |
Induction of melanoma in TPras transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Albinism; Animals; Carcinoma; Gene Expression Regulation; Genes, ras; Genetic Predisposition to Disease; Hair Color; Hyperplasia; Melanocytes; Melanoma; Mice; Mice, SCID; Mice, Transgenic; Monophenol Monooxygenase; Neoplasm Metastasis; Neoplasms, Radiation-Induced; Papilloma; Promoter Regions, Genetic; Skin Neoplasms; Skin Pigmentation; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1999 |
Increased susceptibility to carcinogen-induced mammary tumors in MMTV-Cdc25B transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; cdc25 Phosphatases; Cell Cycle Proteins; Epithelial Cells; Gene Expression Regulation, Viral; Genetic Predisposition to Disease; Isoenzymes; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred CBA; Mice, Transgenic; Phosphoprotein Phosphatases; Phosphorylation; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Terminal Repeat Sequences; Transgenes | 1999 |
Allelotype analysis of chemically induced squamous cell carcinomas in F(1) hybrids of two inbred mouse strains with different susceptibility to tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Carcinogens; Carcinoma, Squamous Cell; Chimera; Crosses, Genetic; Disease Progression; Genetic Predisposition to Disease; Genotype; Humans; Loss of Heterozygosity; Mice; Mice, Inbred SENCAR; Microsatellite Repeats; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Microsatellite DNA variants between the inbred SENCAR mouse strains.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Genetic Markers; Genetic Predisposition to Disease; Genetic Variation; Genotype; Mice; Mice, Inbred SENCAR; Microsatellite Repeats; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 2000 |
Genetics of chemical carcinogenesis: analysis of bidirectional selective breeding inducing maximal resistance or maximal susceptibility to 2-stage skin tumorigenesis in the mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Genetic Predisposition to Disease; Hair Color; Male; Mice; Mice, Inbred Strains; Quantitative Trait, Heritable; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 2000 |
Overexpression of plasminogen activator inhibitor type 2 in basal keratinocytes enhances papilloma formation in transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Differentiation; Crosses, Genetic; Epidermal Cells; Epidermis; Female; Gene Expression; Genetic Predisposition to Disease; Keratinocytes; Male; Mice; Mice, Inbred CBA; Mice, Transgenic; Papilloma; Plasminogen Activator Inhibitor 2; Polymerase Chain Reaction; Rabbits; Skin Neoplasms; Urokinase-Type Plasminogen Activator | 2001 |
High susceptibility of transgenic rats carrying the human c-Ha-ras proto-oncogene to chemically-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Genetically Modified; Carcinogens; Cell Transformation, Neoplastic; Female; Genes, ras; Genetic Predisposition to Disease; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Mas; Rats | 2001 |
DMBA-induced toxic and mutagenic responses vary dramatically between NER-deficient Xpa, Xpc and Csb mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; DNA Helicases; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Fibroblasts; Genetic Predisposition to Disease; Mutagens; Mutation; Poly-ADP-Ribose Binding Proteins; Sister Chromatid Exchange; Skin; Xeroderma Pigmentosum Group A Protein | 2001 |
Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p16; Embryo, Mammalian; Female; Fibroblasts; Gene Deletion; Genes, p16; Genes, ras; Genetic Predisposition to Disease; Humans; Male; Melanoma, Experimental; Mice; Point Mutation; Proteins; Tumor Suppressor Protein p14ARF | 2001 |
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Embryo, Mammalian; Female; Fibroblasts; Gene Deletion; Gene Targeting; Genes, p16; Genetic Predisposition to Disease; Male; Mice; Mice, Knockout; Neoplasms; Proteins; T-Lymphocytes; Thymus Gland; Tumor Suppressor Protein p14ARF; Urethane | 2001 |
RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animals; Blotting, Western; Carcinogens; Cell Adhesion; Cell Line, Transformed; Dose-Response Relationship, Drug; Fibroblasts; Fibronectins; Gene Deletion; Genetic Predisposition to Disease; Growth Substances; Homozygote; Mice; Mice, Transgenic; Models, Genetic; Neoplasms; rhoB GTP-Binding Protein; Signal Transduction; Skin Neoplasms; Time Factors; Transforming Growth Factor beta | 2001 |
Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetyltransferases; Animals; Animals, Genetically Modified; Carcinogens; Cattle; Genetic Predisposition to Disease; Immunohistochemistry; Keratinocytes; Keratins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Plasmids; Promoter Regions, Genetic; Putrescine; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2002 |
Enhanced skin carcinogenesis in cyclin D1-conditional transgenic mice: cyclin D1 alters keratinocyte response to calcium-induced terminal differentiation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcium; Carcinogens; Cell Differentiation; Cell Division; Cyclin D1; Gene Expression Regulation; Genes, ras; Genetic Predisposition to Disease; Humans; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Skin Neoplasms | 2002 |
Genetic control of susceptibility to diethylnitrosamine and dimethylbenzanthracene carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diethylnitrosamine; Female; Genetic Predisposition to Disease; Liver; Liver Neoplasms; Male; Mammary Neoplasms, Experimental; Necrosis; Neoplasms, Experimental; Rats | 1991 |