9,10-dimethyl-1,2-benzanthracene has been researched along with Experimental Mammary Neoplasms in 1637 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 830 (50.70) | 18.7374 |
| 1990's | 363 (22.17) | 18.2507 |
| 2000's | 247 (15.09) | 29.6817 |
| 2010's | 165 (10.08) | 24.3611 |
| 2020's | 32 (1.95) | 2.80 |
| Authors | Studies |
|---|---|
| Patel, P; Shah, J | 1 |
| Lin, X; Ni, H; Sun, Z; Xiong, Y; Yang, L | 1 |
| Awounfack, FC; Kada, MM; Kalgonbe, AY; Mindang, ELN; Ndinteh, DT; Njamen, D; Zingue, S | 1 |
| Akduman, I; Ateş Alkan, F; Aydinalp, C; Joof, S; Kepil, N; Onemli, E; Pastacı Özsobacı, N; Rekik, I; Yilmaz, T | 1 |
| Elhabal, SF; Elwy, HM; Fawzi, NM; Hamza, AA; Hassanin, SO; Khasawneh, MA | 1 |
| Bessonneau, V; Chen, Z; Dang, NM; Gurdogan, H; Hillegass, M; Joshi, S; Kanefsky, J; Rahulkannan, V; Rudel, R; Russo, J; Santucci-Pereira, J; Schneider, SS; Ser-Dolansky, J; Su, Y | 1 |
| Aldhahrani, A; Ali, OM; Amer, HH; Elhenawy, A; Nassan, MA; Swelum, AA; Zaki, YH | 1 |
| Kurhaluk, N; Tkachenko, H | 1 |
| Aryandono, T; Fidianingsih, I; Herwiyanti, S; Sunarti, S; Widyarini, S | 1 |
| Al-Amer, OM; Albrakati, A; Alsagaby, SA; Alsharif, KF; Bawazir, WM; Oyouni, AAA; Seshadri, VD | 1 |
| Bartlett, AP; Harman, RM; Jerry, DJ; Majhi, PD; Miller, JL; Van de Walle, GR | 1 |
| A Abdelghaney, A; A Ali, A; A Alshrief, D; A Emara, A; A Hassan, A; A Hussein, M; A Muhammad, S; A Shalaby, M; Abd Elrahman, AM; Abdel-Maksoud, MA; El-Ella, AA; Gamal El Din, MA; H Mohamed, A; M Bastawey, A; M Maher, A; M Mohamed, M; Mostafa, H; N Al-Wadayi, AM; Nasr-Eldin, MS; S Ewees, A | 1 |
| El-Sherbiny, M; Ibrahim, TM; Sabaa, M; Said, E; Salem, HA; Sharawy, MH | 1 |
| Akrom, A; Darmawan, E; Hidayati, T; Indrayanti, I | 1 |
| Abde-Alaziz, AA; Adam, AH; Ali, AE; Beltagy, DM; El-Rashidy, FH; Shaban, NZ; Talaat, IM | 1 |
| Bhattacharjee, K; Choudhury, Y; Laskar, YB; Mazumder, PB; Nath, M; Talukdar, AD | 1 |
| Gan, H; Mohan, SK; Veeraraghavan, VP; Xie, X; Zhang, Y; Zheng, L; Zhou, Q | 1 |
| Białek, A; Białek, M; Czauderna, M | 1 |
| Gestl, SA; Gunther, EJ; Li, S | 1 |
| Chen, D; Deng, Z; Hong, X; Li, Q; Li, S; Li, Y; Nong, J; Tang, L; Wang, B; Wu, M; Xiao, Y; Xue, L; Zeng, X | 1 |
| Ndinteh, DT; Nguedia, MY; Njamen, D; Tueche, AB; Yadji, V; Yaya, AJG; Zingue, S | 1 |
| Arijana, IGKN; Ghufron, M; Haryana, SM; Mustofa, M; Sriwidyani, NP; Suwito, H; Wahyuniari, IAI; Widyarini, S | 1 |
| Jothi, EA; Lv, P; Xiao, Z; Yang, J; Zhang, H | 1 |
| Chen, J; Chen, W; Luo, D; Wang, W; Wang, Y; Xia, Y | 1 |
| Grishina, M; Pathak, P; Potemkin, V; Rimac, H; Verma, A | 1 |
| Gul, HF; Ilhan, N; Kuloglu, T; Ozercan, IH | 1 |
| Ascensão, L; Cabrita, AS; Cardoso, M; Coelho, JMP; Costa, E; Faísca, P; Ferreira-Gonçalves, T; Figueiredo, IV; Gaspar, MM; Reis, CP | 1 |
| Bernhardt, SM; Du, H; Evdokiou, A; Glynn, DJ; Hodson, LJ; Ingman, WV; Robertson, SA; Sun, X; Woolford, L; Yan, C | 1 |
| Dueñas, Z; Garcia-Laguna, G; Gerena-Cruz, MF; Monroy-Gomez, J; Sánchez, AY | 1 |
| Bloy, N; Buqué, A; Galluzzi, L; Humeau, J; Kroemer, G; Perez-Lanzón, M; Petroni, G; Sato, A; Yamazaki, T | 1 |
| Plante, I | 1 |
| Jayaraj, R; Kodiveri Muthukaliannan, G; Madhyastha, H; Mathiyazhagan, J; Siva, R | 1 |
| Wang, X; Yanqin, T; Yuwen, T | 1 |
| Samuel Metibemu, D | 1 |
| Duderstadt, EL; Samuelson, DJ; Sanders, MA | 1 |
| Allen, AM; Alorro, M; Chand, AL; Clyne, CD; Connelly, AA; Coulson, R; Deb, S; Ernst, M; George, AJ; Hannan, NJ; Harrison, CA; Kumar, B; Lazarus, KA; Liew, SH; Morrow, RJ; O'Toole, SA; Parslow, AC; Poh, A; Putoczki, T; Vargas, AC; Walton, KL; Yeap, EFW; Yee, NS | 1 |
| Barbisan, LF; Bidinotto, LT; da Silva, FRM; Grassi, TF; Zapaterini, JR | 1 |
| Bhatia, D; Bishayee, A; Mandal, A | 2 |
| Ananthakrishnan, D; Gunasekaran, K; Jayaganesh, R; Pugalendhi, P; Rajakumar, T | 1 |
| Bodduluru, LN; Ellutla, M; Kalyankumarraju, M; Karnam, KC; Kasala, ER; Lahkar, M; Uppulapu, SK | 1 |
| Ananthakrishnan, D; Gunasekaran, K; Pugalendhi, P; Rajakumar, T; Thilagavathi, S | 1 |
| Abd El-Rahman, SS; Nashaat, H; Shehab, G | 1 |
| Berton, TR; Conti, CJ; Fuchs-Young, R; Hursting, SD; Lambertz, IU; Luo, L; Schwartz, SL | 1 |
| Brunotto, M; Garay, MI; Madzzuduli, G; Pasqualini, ME; Repossi, G; Scherma, ME; Silva, RA | 1 |
| Artac, H; Baltaci, AK; Baltaci, SB; Emsen, A; Mogulkoc, R | 1 |
| Hultborn, R | 1 |
| Jha, S; Kumar, A; Pattanayak, SP; Sunita, P | 1 |
| Al-Dhaheri, W; Hassouna, I; Karam, SM | 1 |
| Alessandra-Perini, J; de Moura, RS; Dos Santos, TA; Junior, AP; Machado, DE; Nasciutti, LE; Perini, JA; Rodrigues-Baptista, KC; Souza, PJC | 1 |
| Ananda, H; Rangappa, KS; Rangappa, S; Sharath Kumar, KS; Sudhanva, MS | 1 |
| Bose, P; Haque, MW; Lapenna, A; Pattanayak, SP; Siddique, MUM; Sunita, P | 1 |
| Ashrafi, M; Karimi, B; Shomali, T; Yektaseresht, A | 1 |
| Cao, X; Feng, X; Howard, EW; Jiang, Y; Kim, YM; Kosanke, SD; Li, S; Ma, Z; Parris, AB; Yang, S; Yang, X | 1 |
| Jayaganesh, R; Pugalendhi, P; Saminathan, U; Subramaniyan, S | 1 |
| Anandakumar, P; Sakthisekaran, D; Vanitha, MK | 1 |
| Frenkel, DD; Gorev, NP; Ionov, ID; Roslavtseva, LA | 1 |
| Cerqueira, GS; da Mata, AMOF; de Alencar, MVOB; de Lima, RMT; Dos Reis, AC; E Sousa, JMC; Ferreira, PMP; Filho, JWGO; Islam, MT; Melo-Cavalcante, AAC; Mubarak, MS; Paz, MFCJ | 1 |
| Carney, E; Clarke, R; De Oliveira Andrade, F; FitzGerald, K; Hilakivi-Clarke, L; Hu, R; Yu, W; Zhang, X | 1 |
| Chen, M; Jiang, W; Liao, X; Mao, A; Ou, C; Qin, Q; Tan, Q; Wei, C; Yang, C; Yang, W; Ye, X | 1 |
| Isabella, S; Mirunalini, S | 1 |
| Awasthi, S; Horne, D; Salgia, R; Singhal, J; Singhal, SS; Vonderfecht, S | 1 |
| Balasubramanian, P; Benbrook, D; Csiszar, A; Sonntag, WE; Springo, Z; Tarantini, S; Ungvari, Z; Yabluchanskiy, A; Zhang, XA | 1 |
| Nicol, CJB; Rubino, RE; Shi, JY | 1 |
| Pachaiappan, P; Rajendran, J; Subramaniyan, S | 1 |
| Ilhan, N; Ozercan, IH; Susam, S; Tatar, O | 1 |
| Bhatia, D; Bishayee, A; Darvesh, AS; Mandal, A; Thoppil, RJ | 1 |
| Cho, YM; Imai, T; Kitahashi, T; Nishikawa, A; Ogawa, K; Takahashi, M; Takami, S | 1 |
| Matthews, SB; Playdon, MC; Thompson, HJ | 1 |
| Askeland, RW; Fisher, RA; Maity, B; O'Malley, Y; Stewart, A; Sugg, SL | 1 |
| Balamurugan, A; Balasubramanian, MP; Nandakumar, N; Rengarajan, T | 1 |
| Kadir, EA; Othman, NH; Sulaiman, SA; Yahya, NK | 1 |
| Carón, RW; Cuello Carrión, FD; Jahn, GA; López-Fontana, CM; Maselli, ME; Santiano, FE; Sasso, CV; Semino, SN | 1 |
| Apostoli, AJ; Di Lena, MA; Nicol, CJ; Peterson, NT; Rubino, RE; Schneider, MM; SenGupta, SK; Skelhorne-Gross, GE | 1 |
| Altenburg, J; Camarillo, I; Harvey, KA; Jones-Hall, Y; Mariash, C; Siddiqui, RA; Terry, C; Walker, C; Xu, Z | 1 |
| Agnihotri, N; Bhatnagar, A; Kansal, S; Negi, AK | 1 |
| Czepas, J; Gwoździński, K; Koceva-Chyła, A; Piasecka-Zelga, J; Pieniążek, A; Tabaczar, S | 1 |
| Besch-Williford, CL; Cook, M; Hyder, SM; Mafuvadze, B; Xu, Z | 1 |
| Nandhakumar, E; Purushothaman, A; Sachdanandam, P | 1 |
| Cabrita, AM; Colaço, B; Cova, TF; Lopes, AC; Pais, AA; Pereira, JL | 1 |
| Bouker, KB; de Assis, S; Hilakivi-Clarke, LA; Jin, L; Wang, M | 1 |
| Bialek, S; Bobrowska-Korczak, B; Jezierska, E; Makowska, J; Skrajnowska, D; Tokarz, A | 1 |
| Lakshmi, A; Subramanian, S | 1 |
| Bishayee, A; Mandal, A | 1 |
| Croxford, R; Deghan Manshadi, S; Ishiguro, L; Kim, YI; Medline, A; Renlund, R; Sohn, KJ | 1 |
| Fang, Y; Fu, Q; Gao, D; Li, L; Li, Y; Ma, Z; Wang, F; Yu, L; Yu, Z; Zhang, Q | 1 |
| Carón, RW; Ezquer, ME; Hapon, MB; Jahn, GA; López-Fontana, CM; Pistone-Creydt, V; Santiano, FE; Sasso, CV | 1 |
| Arivazhagan, L; Sorimuthu Pillai, S | 1 |
| Elangovan, N; Hari, N; Kaliaperumal, J; Padarthi, P | 1 |
| Bobrov, N; Bojková, B; Bomba, A; Demečková, V; Kassayová, M; Kisková, T; Kubatka, P; Mikeš, J; Orendáš, P; Péč, M; Strojný, L | 1 |
| Alves-Júnior, MJ; Anhê, GF; de Moraes Schenka, NG; De Souza, PC; de Souza, VB; Hyslop, S; Jampietro, J; Rennó, AL; Rocha, RM; Schenka, AA; Soares, FA; Vassallo, J | 1 |
| Baskaran, K; Ilakkia, A; Periyasamy, K; Sakthisekaran, D; Selvaraj, S; Vanitha, K | 1 |
| Chen, C; Ge, GZ; He, BL; Jiao, JL; Lv, LB; Wang, CY; Xia, HJ; Zhang, HL; Zhang, YX | 1 |
| Kim, BR; Kim, JS; Liu, KH; Park, JH; Seo, JY; Suh, HJ; Sung, MK | 1 |
| Altun, A; Duger, C; Inan, DS; Isbir, C; Koksal, B; Ozdenkaya, Y; Saraydin, SU; Soylu, S; Turan, M; Yasti, C | 1 |
| Pugalendhi, P; Rajakumar, T; Thilagavathi, S | 1 |
| Balasubramanian, MP; Ganesh, MK; Nandakumar, N; Nishigaki, I; Rajendran, P; Rengarajan, T | 1 |
| Apostoli, AJ; Di Lena, MA; Nicol, CJ; Peterson, NT; Roche, JM; Rubino, RE; Schneider, MM; SenGupta, SK | 1 |
| Khan, HB; Palanivelu, S; Panchanadham, S; Vani, S | 1 |
| Gayen, JR; Hussain, KM; Mishra, DP; Rama Raju, KS; Singh, SK; Singh, SP; Taneja, I; Tripathi, A; Wahajuddin, M | 1 |
| Ahmed, S; Jamdade, V; Kumar, P; Lahkar, M; Mundhe, NA; Mundhe, S | 1 |
| Gadzinski, B; Kazimierczuk, A; Klepacz, M; Korczak, BB; Makowska, J; Skrajnowska, D; Tokarz, A | 1 |
| Escrich, E; Escrich, R; Moral, R; Rodríguez-Miguel, C; Solanas, M; Vela, E | 1 |
| Bechberger, JF; Laird, DW; Naus, CC; Stewart, MK; Welch, I | 1 |
| Chidambaram, R; Gokul Raj, K; Pandi, M; Ravikumar, V; Varunkumar, K | 1 |
| Aziz, MH; Chen, X; DeFrain, C; Luo, Y; Osland, J; Shi, X; Yuan, R; Zhang, Q | 1 |
| Bhatia, D; Bhattacharyya, P; Bishayee, A; Mandal, A | 1 |
| Besch-Williford, C; Cook, MT; Ellersieck, MR; Goyette, S; Hyder, SM; Mafuvadze, B | 1 |
| Abdel-Rahman, S; Awad, D; Bassiouny, A; Haggag, A; Shaban, N; Talaat, I | 2 |
| Guo, SC; He, YU; Li, QQ | 1 |
| Bornschein, RL; Gear, R; Govindarajah, V; Ho, SM; Leung, YK; Medvedovic, M; Ying, J | 1 |
| Białek, A; Tokarz, A; Zagrodzki, P | 1 |
| Agnihotri, N; Bhatnagar, A; Negi, AK | 1 |
| Choi, MR; Christov, K; Ivancic, D; Khan, SA; Lee, O | 1 |
| Anandakumar, P; Baskaran, K; Ilakkia, A; Periyasamy, K; Revathi Mani, B; Sakthisekaran, D; Saravanan, D; Selvaraj, S; Vanitha, MK; Venkateswari, R | 1 |
| Awounfack, CF; Bishayee, A; Cisilotto, J; Creczynski-Pasa, TB; Magne Nde, CB; Mefegue, FA; Melachio Tanekou, TT; Michel, T; Ndinteh, DT; Njamen, D; Sandjo, LP; Silihe, KK; Tueche, AB; Winter, E; Zingue, S | 1 |
| Barbisan, LF; Bolaños-Jiménez, F; Castro, IA; Cozzolino, SM; Fontelles, CC; Guido, LN; Ong, TP; Pires, VC; Rosim, MP | 1 |
| Dora, CP; Jena, SK; Pawar, H; Singh, C; Suresh, S; Varthya, M | 1 |
| Devlin, KL; Harrison, LM; Hursting, SD; Lashinger, LM; LeBourgeois, P; Mambo, E; Sanford, T | 1 |
| Jha, S; Kumar, A; Pattanayak, SP | 1 |
| Ananda, H; Hegde, M; Kumar, KS; Rangappa, KS | 1 |
| Abba, MC; Aldaz, CM; Gaddis, S; Kil, H; Lee, J; Lu, Y; Shen, J; Simper, MS; Takata, Y; Zhong, Y | 1 |
| Barnard, NJ; Huang, MT; Kundu-Roy, T; Lin, Y; Liu, F; Liu, Z; Lou, YR; Matsuura, I; Suh, N; Wang, G; Wang, XF | 1 |
| Bouker, KB; Clarke, R; Cook, KL; Cruz, MI; de Assis, S; Hilakivi-Clarke, L; Hu, R; Jin, L; Nguyen, N; Wang, X; Wang, Y; Wärri, A; Wehrenberg, B; Xuan, J; Zhang, X; Zwart, A | 1 |
| Devasagayam, TP; Janardhanan, KK; Nitha, B; Smina, TP | 1 |
| Clarke, R; Cook, KL; Cruz, IM; Doerge, D; Helferich, W; Hilakivi-Clarke, L; Riskin, J; Rosim, M; Warri, A; Zhang, X | 1 |
| de Miguel, C; Escrich, E; Manzanares, MÁ; Ruiz de Villa, MC; Santella, RM; Solanas, M | 1 |
| Airio, M; Dings, RP; Mäkelä, S; Saarinen, NM; Smeds, AI; Wärri, A | 1 |
| Fukamachi, K; Imada, T; Ohshima, Y; Tsuda, H; Xu, J | 1 |
| Cerven, DR; de George, G; Iatropoulos, MJ; von Keutz, E; Williams, GM | 1 |
| Gruenstein, M; Meranze, DR; Shimkin, MB; Thatcher, D | 1 |
| Behboudi, A; Nilsson, J; Samuelson, E; Szpirer, C; Walentinsson, A | 1 |
| Abbadessa, G; Carletti, M; Dacasto, M; Di Carlo, F; Gardini, G; Girolami, F; Nebbia, C; Piccione, F; Racca, S; Spaccamiglio, A | 1 |
| Al mslmani, MA; Moselhy, SS | 1 |
| Adamovic, T; Jacob, HJ; McAllister, D; Rowe, JJ; Sugg, SL; Wang, T | 1 |
| Al-Dhaheri, WS; Al-Salam, S; Hassouna, I; Karam, SM | 1 |
| Baston, DS; Birnbaum, LS; Denison, MS; La Merrill, M; Pomp, D; Threadgill, DW | 1 |
| Das, SK; Mukherjee, S; Mukhopadhyay, S; Sinha Roy, S | 1 |
| Hu, Y; Ren, YP; Shuai, YF; Tang, HB; Wu, YP; Zhu, ZY | 1 |
| Bae, S; Cho, CK; Jang, JJ; Jeoung, D; Kang, CM; Lee, HJ; Lee, SS; Lee, YJ; Lee, YS | 1 |
| Berry, MJ; Collier, AC; Lin, Y; Liu, W; Panee, J | 1 |
| Hawthorne, M; Huma, L; Kopelovich, L; McCormick, DL; Mehta, RG; Moriarty, RM; Naithani, R; Steele, VE | 1 |
| Blusztajn, JK; Davison, JM; Kovacheva, VP; Mellott, TJ; O'Brien, MJ; Rogers, AE; Yang, S | 1 |
| Abu-Alruz, K; Abu-Samak, M; Al-Qudah, J; Al-Widyan, O; Khataibeh, M | 1 |
| Cho, YM; Hirose, M; Imai, T; Nishikawa, A; Takami, S | 1 |
| Kale, RK; Kar, A; Mishra, P | 1 |
| Kawaguchi, H; Umekita, Y; Yoshida, H | 1 |
| Gupta, J; Kumar, P; Tikoo, K | 1 |
| Moen, I; Nedrebø, T; Reed, RK; Rubin, K; Salnikov, AV; Stuhr, LE; Wiig, H | 1 |
| Alakavuklar, M; Canda, T; Cehreli, R; Guner, G; Gurel, D; Kocdor, H; Kocdor, MA; Yilmaz, O | 1 |
| Al-Ghananeem, AM; Balko, JM; Black, EP; Malkawi, AH; Mourad, W; Muammer, YM; Romond, E | 1 |
| Anandan, R; Manikandan, P; Nagini, S; Vinothini, G | 1 |
| Abeyama, K; Souda, M; Umekita, Y; Yoshida, H | 1 |
| Hurst, K; Jansson, D; Lau, R; Niu, MY; Perez-Iratxeta, C; Pratt, MA; Robertson, SJ; Tibbo, E | 1 |
| Hirtreiter, C; Ishibashi, K; Nishino, T; Nishino, Y | 1 |
| Adamovic, T; Andrae, JW; Cuppen, E; Guryev, V; Jacob, HJ; McAllister, D; Sugg, SL; Wang, X | 1 |
| Handel-Fernandez, ME; Herbert, LM; Ilkovitch, D; Iragavarapu-Charyulu, V; Lopez, DM | 1 |
| Murugan, RS; Nagini, S; Vinothini, G | 1 |
| Manikandan, R; Muthumary, J; Pandi, M | 1 |
| Budde, A; Karl, T; Lautenbach, A; Nave, H; Teichmann, B; Vieten, G; Wrann, CD | 1 |
| Chen, BQ; Dong, HW; Han, XH; Liu, JR; Liu, Q; Parry, JW; Sun, CH; Sun, WG; Sun, XR; Wang, Q; Yang, BF | 1 |
| Blanchard, A; Chrétien, M; Fresnosa, A; Iwasiow, B; Murphy, LC; Myal, Y; Seidah, N; Shiu, RP; Silha, J; Yarmill, A | 1 |
| Chen, JJ; Kim, HJ; Kim, SY; Laxmi, YR; Liu, X; Okamoto, K; Okamoto, Y; Shibutani, S; Suzuki, N; Zhang, G | 1 |
| Chatterjee, M; Ghosh, B; Janarthan, M; Manna, S; Rana, A; Rana, B | 1 |
| Chea, K; Currier, N; Dominguez, I; Hlavacova, M; Seldin, DC; Sussman, DJ | 1 |
| Furth, PA; Miermont, AM; Parrish, AR | 1 |
| Hazra, DK; Khoobchandani, M; Ojeswi, BK; Srivastava, MM | 1 |
| Das, SK; Guillory, B; Mukherjee, S; Mukhopadhyay, S | 1 |
| Bishayee, A; Chatterjee, M; Patel, MA; Waghray, A | 1 |
| Davis, J; Hilakivi-Clarke, L; Khan, G; Michels, KB; Nielsen, TS | 1 |
| Bhadauria, S; Mishra, J; Mishra, R; Murthy, PK; Murthy, PS; Tiwari, A | 1 |
| Alonso-González, C; Alvarez-García, V; Cos, S; González, A; Martínez-Campa, C; Mediavilla, MD; Sánchez-Barceló, EJ | 1 |
| Mead, MN | 1 |
| Manoharan, S; Pugalendhi, P | 1 |
| Chatterjee, M; Janarthan, M; Manivannan, R; Rana, A | 1 |
| Belles, CA; Brown, NM; Kim, MO; Lindley, SL; Setchell, KD; Witte, DP; Zimmer-Nechemias, L | 1 |
| Benakanakere, I; Besch-Williford, C; Carroll, CE; Hyder, SM | 1 |
| Adamovic, D; Adamovic, T; Jacob, HJ; Lazar, J; McAllister, D; Moreno, C; Rowe, JJ; Sugg, SL; Wang, T | 1 |
| Chen, JJ; Kim, HJ; Laxmi, YR; Liu, X; Okamoto, K; Okamoto, Y; Shibutani, S; Suzuki, N; Zhang, G | 1 |
| Aggarwal, R; Agnihotri, N; Kansal, S; Kaur, R; Negi, AK; Sarotra, P; Sharma, G | 1 |
| Branstetter, D; Dougall, WC; Erwert, R; Gonzalez-Suarez, E; Jacob, AP; Jones, J; Miller, R; Pinkas, J; Roudier-Meyer, MP | 1 |
| Białek, A; Bielecki, W; Dudek, A; Kazimierska, W; Tokarz, A | 1 |
| Boyd, AL; Humber, B; Kerr, LR; Salleh, A; Tomes, L; Yee, J | 1 |
| Bhadauria, S; Mishra, R; Murthy, PK; Murthy, PS | 1 |
| Chen, J; Croxford, R; Kim, YI; Lee, H; Ly, A; Medline, A; Renlund, R; Sie, KK; Sohn, KJ; Thompson, LU | 1 |
| Gould, MN; Haag, JD; Meilahn, AL; Remfert, JL; Samuelson, DJ; Veillet, AL | 1 |
| Alpy, F; Buache, E; Chenard, MP; Etique, N; Muckensturm, M; Reina-San-Martin, B; Rio, MC; Stoll, I; Tomasetto, C | 1 |
| Białek, S; Bobrowska, B; Seweryn, M; Tokarz, A | 1 |
| Costa, I; de Villa, MC; Escrich, E; Escrich, R; Moral, R; Solanas, M; Vela, E | 1 |
| Barbisan, LF; de Camargo, JL; Grassi, TF; Rodrigues, MA | 1 |
| Ghandhi, JL; Iqbal, A; Kapadia, AD; Naseemuddin, M; Nasti, TH; Yusuf, N | 1 |
| Godschalk, RW; Hilakivi-Clarke, L; Nielsen, TS; Purup, S; Wärri, A | 1 |
| Chatterjee, M; Das, S; Janarthan, M; Manna, S | 1 |
| Crowell, JA; De Flora, SL; Grubbs, CJ; Heckman, BM; Juliana, MM; Lubet, RA; Steele, VE | 1 |
| Haag, JD; Samuelson, DJ; Sanders, J | 1 |
| Keri, RA; Weber Lozada, K | 1 |
| Hamada, T; Hatanaka, K; Kawaguchi, H; Souda, M; Tanimoto, A; Umekita, Y; Yoshioka, T | 1 |
| Aceves, C; Anguiano, B; Delgado, G; Gonsebatt, ME; Molina-Servín, ED; Petrosyan, P; Soriano, O | 1 |
| Chatterjee, M; Das, S; Janarthan, M; Ramachandran, HK | 1 |
| Chen, EP; Chodosh, LA; Fitzgerald, GA; Lawson, JA; Markosyan, N; Ndong, VN; Smyth, EM; Sterner, CJ; Yao, Y | 1 |
| Gould, MN; Haag, JD; Mau, B; Samuelson, DJ; Sharma, D; Smits, BM; Woditschka, S | 1 |
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| King, MM; McCay, PB | 1 |
| Ciocca, DR; Russo, IH; Russo, J; Tay, LK | 1 |
| Dodson-Simmons, O; Go, K; Kartha, G; Neeman, M; Santodonato, JP | 1 |
| De Loecker, W; Goddeeris, P; Lauwerijns, JM; Leyman, AM | 1 |
| Shoyab, M | 1 |
| Butel, JS; Medina, D; Richards, CS; Steiner, MR | 1 |
| Brooks, SC; Corombos, J; Horwitz, JP; Hughes, DE; Hughes, R; Ludwig, EH; Odden, D; Rozhin, J; Wilson, E | 1 |
| Custer, RP; Dickens, MS; Schaefer, FV; Sorof, S; Tonelli, QJ | 1 |
| Feenstra, A; Nolten, GM; Reiffers, S; Talma, AG; Vaalburg, W; van der Molen, HD; Wiegman, T; Woldring, MG | 1 |
| Bennett, DR; Black, LJ; Clemens, JA; Jones, CD | 1 |
| Katayama, I; Miura, M; Shimizu, M; Wajima, O | 1 |
| Carter, CA; Ip, MM; Milholland, RJ; Shea, W | 1 |
| Russo, J; Tay, LK | 3 |
| Ballou, RJ; Safa, AR; Tseng, MT | 2 |
| Donegan, WL; Klamer, TW; Max, MH | 1 |
| de Thibault de Boesinghe, L; Eechaute, W; Lacroix, E | 1 |
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| Gómez, CJ; Goya, RG; Sosa, YE | 1 |
| Boylan, ES; Calhoon, RE | 3 |
| Lane, HW; Medina, D; Shepherd, F | 1 |
| Brooks, SC; De Loecker, W; Janssens, JP; Wittevrongel, C | 1 |
| Johnson, ML; Levy, J; Rosen, JM; Supowit, SC; Yu-Lee, LY | 1 |
| Horvath, PM; Ip, C | 1 |
| Aylsworth, CF; Meites, J; Sylvester, PW; Van Vugt, DA | 3 |
| DeHoog, JV; Scieszka, KM; Senn, ER; Welsch, CW | 1 |
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| Demuth, RJ; Fletcher, WS; Jackson, CF; Miller, SH; Palmquist, M; Swanson, J; Wong, J | 1 |
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| Major, N; McCormick, DL; Moon, RC | 1 |
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| Bernhauer, H; Egginger, G; Kranzfelder, G; Schönenberger, H; von Angerer, E | 1 |
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| Barnes, S; Holland, M; Lamartiniere, CA; Moore, J | 1 |
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| Ahlers, I; Ahlersová, E; Bojková, B; Kubatka, P; Mníchová, M; Mocková, K | 1 |
| Ahlers, I; Ahlersová, E; Bojková, B; Kubatka, P; Mníchová, M; Mociková, K | 1 |
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| Buschow, RA; Costlow, ME; McGuire, WL | 2 |
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| Heuson, JC; Heuson-Stiennon, J; Legros, N; Pasteels, JL | 1 |
| Grubbs, CJ; Moon, RC; Sporn, MB | 1 |
| Bojsen, J; Møoller, U | 1 |
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| de Iturri, GC; Welsch, CW | 1 |
| Aspegren, K; Biörklund, A; Tropé, C | 1 |
| Davies, P; Golder, MP; Griffiths, K; Nicholson, RI | 1 |
| DeSombre, ER; Johnson, ES; Seely, JH; White, WF | 1 |
| Bradley, CJ; Campbell, GA; Kledzik, GS; Marshall, S; Meites, J | 1 |
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| Medina, D; Warner, MR | 1 |
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| Ohi, Y; Yoshida, H | 1 |
| Ebert, K; Knuppen, R; Michna, H; Vollmer, G | 1 |
| Abou-Issa, H; Koolemans-Beynen, A; Meredith, TA; Webb, TE | 1 |
| Horiuchi, R; Iino, Y; Ishikita, T; Maemura, M; Morishita, Y; Ohwada, S; Sugamata, N; Yokoe, T; Yoshida, M | 1 |
| Lin, RI; Liu, J; Milner, JA | 1 |
| Gould, MN; Haag, JD; Newton, MA | 1 |
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| Ip, C; Lisk, DJ; Stoewsand, GS | 1 |
| Boylan, E; Cohen, LA; Epstein, M; Zang, E | 1 |
| Imai, S; Yamamoto, H; Yamamoto, I | 1 |
| Cho-Chung, YS; Døskeland, SO; Houge, G | 1 |
| Inada, K; Matsuo, S; Nakashima, Y; Ogawa, M; Yamashita, J; Yamashita, S | 3 |
| Earashi, M; Kitagawa, H; Miyazaki, I; Mizukami, Y; Noguchi, M; Ohta, N; Thomas, M | 1 |
| Nelshoppen, JM; Scardefield, S; Singletary, KW; Wallig, M | 1 |
| Ganther, H; Ip, C | 1 |
| Comaru-Schally, AM; Engel, J; Harleman, JH; Hilgard, P; Reissmann, T; Schally, AV | 1 |
| Kosaka, A; Yamashita, A | 1 |
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| Chae, YH; Cohen, LA; el-Bayoumy, K; Meschter, C; Reddy, BS; Upadhyaya, P | 1 |
| Henderson, BR; Kefford, RF; Phillips, SM; Ramshaw, IA; Tansey, WP | 1 |
| van Stratum, P; Verschuren, PM; Vles, RO; Zaalberg, J; Zevenbergen, JL | 1 |
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| Arron, RJ; Bogdanovic, RP; Brandes, LJ; Fang, W; Hogg, GR; LaBella, FS; Tong, J; Warrington, RC; Zaborniak, CL | 1 |
| Gould, MN; Haag, JD; Lindstrom, MJ | 1 |
| Bandyopadhyay, AM; Banerjee, MR; Das, SK; Jia, TZ | 1 |
| Ganther, HE; Ip, C | 3 |
| Ahmad, S; Crowell, PL; Gould, MN; Haag, JD; Kennan, WS; Vedejs, E | 1 |
| Inada, K; Matsuo, S; Misumi, A; Nakashima, Y; Ogawa, M; Yamashita, J; Yamashita, S; Yoshimura, T | 1 |
| Pelletier, G; Rhéaume, E; Simard, J; Tong, Y | 1 |
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| Campbell, JS; Fischer, PW; Giroux, A | 1 |
| Ashino-Fuse, H; Iwaguchi, T; Oikawa, T; Shimamura, M; Tominaga, T; Yoshida, Y | 1 |
| Fendl, KC; Zimniski, SJ | 1 |
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| Bechtel, DH; Belury, MA; Conti, CJ; Fischer, SM; Lee, ML; Leyton, J; Locniskar, M; Maldve, RE; Slaga, TJ | 1 |
| Callens, MJ; De Coster, R; Goeminne, NK; Janssens, BL; Van Ginckel, RF | 1 |
| Escrich, E; Muntané, J; Murillo, J; Ribalta, T; Ruiz de Villa, MC; Saez, S | 1 |
| Gould, MN; Zhang, R | 1 |
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| di Salle, E; Giudici, D; Ornati, G; Panzeri, A; Zaccheo, T | 1 |
| Elson, CE; Gould, MN; Haag, JD; Kennan, WS; Tanner, MA | 1 |
| Kaidoh, T; Uehara, Y; Yasugi, T | 1 |
| Isaacs, JT | 4 |
| Davis, MJ; Klurfeld, DM; Kritchevsky, D; Lloyd, LM; Tulp, OL; Welch, CB | 1 |
| Gienapp, IE; Gudehithlu, KP; Hanissian, SH; Malarkey, WB; Tejwani, GA; Whitacre, CC | 1 |
| Koyasaki, N; Kumaki, T; Miyazaki, I; Mizukami, Y; Noguchi, M; Taniya, T | 1 |
| Eto, I; Grubbs, CJ; Juliana, MM; Whitaker, LM | 1 |
| Chagnaud, JL; Diolez-Bojda, F; Faiderbe, S; Geffard, M; Kerdélhué, B | 1 |
| Iles, RK | 1 |
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| VanderPloeg, LC; Welsch, CW; Wolfrom, DM | 1 |
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| Horiuchi, R; Iino, Y; Owada, S; Sugamata, N; Tago, T; Yoshida, M | 1 |
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| Barsoum, AL; Kurl, RN | 1 |
| Escrich, E; Lizcano, JM; Muntané, J; Ribalta, T; Unzeta, M | 1 |
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| Gilbert, K; Haschek, WM; Liu, JZ; Milner, JA; Parker, HM | 1 |
| Frazier, DL; Overholt, BF; Panjehpour, M; Wilke, AV | 1 |
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| George, WD; McCulloch, P; Purushotham, AD | 1 |
| McNary, MQ; Nelshoppen, J; Odoms, AM; Singletary, KW; Wallig, MA | 1 |
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| Nelshoppen, JM; Singletary, KW | 1 |
| Chin, SF; Ip, C; Pariza, MW; Scimeca, JA | 1 |
| Cavalieri, EL; Devanesan, PD; Higginbotham, S; RamaKrishna, NV; Rogan, EG; Salmasi, S; Todorovic, R | 1 |
| Keith, RE; Lane, HW; Strahan, S; White, MT | 1 |
| Keith, RE; Lane, HW; Strahan, S; Teer, P; White, MT | 1 |
| Senger, D; Torsten, U; Weitzel, HK | 1 |
| Bakker, GH; de Jong, FH; Foekens, JA; Klijn, JG; Lamberts, SW; Portengen, H; Reubi, JC; Setyono-Han, B; van Putten, WL | 1 |
| Fujiki, H; Kobayashi, M; Okuda, T; Ootsuyama, A; Suganuma, M; Sugimura, T; Suguri, H; Takagi, K; Tanooka, H; Yoshizawa, S | 1 |
| Kritchevsky, D | 1 |
| Isaacs, JT; Kyprianou, N | 1 |
| Clayton, MK; Gendron-Fitzpatrick, A; Lasekan, JB; Ney, DM | 1 |
| Gusterson, BA; Rogers, AE; Russo, IH; Russo, J; van Zwieten, MJ; Wellings, SR | 1 |
| Iino, Y; Izuo, M; Ogawa, T; Takikawa, H; Yoshida, M | 1 |
| Izuno, Y; Kusunose, N; Morii, S; Shoji, T; Tsubura, A | 1 |
| Singletary, KW | 1 |
| Dukes, J; Johnson, J; Lane, HW; Teer, P; White, MT | 1 |
| Franke, LA; Hanson, RN; Kaplan, M | 1 |
| Banerji, AP; Rao, LS | 1 |
| Kumaki, T; Noguchi, M | 1 |
| Gimotty, PA; Koszalka, M; Russo, IH; Russo, J | 1 |
| Kumar, R; Medina, D; Sukumar, S | 1 |
| Ichikawa, T; Isaacs, JT; Kyprianou, N | 1 |
| Hussain, SP; Jannu, LN; Kumari, MV; Rao, AR | 1 |
| Gould, MN; Haag, JD; Zhang, R | 1 |
| Baggott, JE; Grubbs, CJ; Ha, T; Hardin, JM; Juliana, MM; Vaughn, WH | 1 |
| Lasekan, JB; Ney, DM | 1 |
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| Komori, Y; Kubodera, A; Oyamada, H; Shimura, N; Tanaka, T | 1 |
| Koyasaki, N; Kumaki, T; Miyazaki, I; Noguchi, M; Taniya, T | 1 |
| Frick, KK; Klurfeld, DM; Kritchevsky, D; Ruggeri, BA | 1 |
| Hussain, SP; Jannu, LN; Ramesha, A; Rao, AR; Rao, N | 1 |
| Bartsch, C; Bartsch, H; Gupta, D; Lippert, TH | 1 |
| Kusunose, N; Morii, S; Shoji, T; Tsubura, A; Yamamoto, M | 1 |
| Escrich, E; Lizcano, JM; Tipton, KF; Unzeta, M | 1 |
| Komaki, K; Konishi, N; Monden, Y; Mori, T; Morimoto, T; Sasa, M; Tanaka, T; Yamakawa, T; Yamamoto, H | 1 |
| Horiuchi, R; Iino, Y; Izuo, M | 1 |
| Eliasberg, SJ; Herr, BL; House, JL; Welsch, CW; Welsch, MA | 1 |
| Abou-Issa, H; Dwivedi, C; Gudehithlu, KP; Malarkey, W; Satter, BC; Sharma, HM; Tejwani, GA | 1 |
| di Salle, E; Ornati, G; Zaccheo, T | 1 |
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| Dunnington, DJ; Jamieson, S; Ormerod, EJ; Rudland, PS; Warburton, MJ | 1 |
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| Chang, AY; Chuang, C; Pandya, KJ; Wierenga, W | 1 |
| Gould, MN; Grau, DR; Moore, CJ; Seidman, LA | 1 |
| Ebihara, K; Matsuda, A; Nishikawa, K; Shibasaki, C; Takahashi, K | 1 |
| Fukatsu, T; Kawaguchi, T; Nagasaka, T; Nakashima, N; Sobue, M; Takeuchi, J; Toida, M; Tsukidate, K | 1 |
| Ashino-Fuse, H; Hiragun, A; Iwaguchi, T; Oikawa, T; Tominaga, T; Yoshida, Y | 1 |
| di Salle, E; Giudici, D; Lombardi, P; Zaccheo, T | 1 |
| Baird, WM; Bandyopadhyay, AM; Banerjee, MR; Das, SK; Delp, CR; Mathiesen, M | 1 |
| Bambara, RA; Hilf, R; Klinge, CM; Zain, S | 2 |
| Davis, MJ; Klurfeld, DM; Kritchevsky, D; Welch, CB | 1 |
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| Dauvois, S; Labrie, F | 1 |
| Corral, J; Cos, S; Garijo, F; Mediavilla, MD; Sánchez-Barceló, EJ | 1 |
| Anderson, JL; Lisk, DJ; Munson, L; Stoewsand, GS | 1 |
| el Etreby, MF; Michna, H; Nishino, Y; Schneider, MR | 3 |
| Klurfeld, DM; Kritchevsky, D; Lloyd, LM; Welch, CB | 1 |
| Campbell, JS; Chavez, ER; Fischer, PW; L'Abbé, MR | 1 |
| Chavez, ER; Fischer, PW; L'Abbé, MR | 1 |
| Ip, C; Thompson, HJ | 1 |
| Bland, KI; Bryant, MS; Ellis, LM; Hogancamp, WE; Sitren, HS; Wittliff, JL | 1 |
| Koyama, H; Miyauchi, K; Noguchi, S; Tahara, H | 1 |
| Furlanetto, RW; Klurfeld, DM; Kritchevsky, D; Ruggeri, BA | 2 |
| Carter, CA; Ip, C; Ip, MM | 2 |
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| Dear, TN; Kefford, RF; McDonald, DA | 1 |
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| Klurfeld, DM; Kritchevsky, D; Welch, CB | 1 |
| Iino, Y; Izuo, M; Takikawa, H | 1 |
| Gutnik, NS; Kartavova, NS; Piatchanina, TV; Sidorik, EP | 1 |
| Carroll, KK; Jacobson, EA; James, KA; Newmark, HL | 1 |
| Elson, CE; Gould, MN; Hoesly, JD; Russin, WA; Tanner, MA | 1 |
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| Monden, A; Morimoto, T; Yamamoto, H | 1 |
| Frederick, J; Russo, IH; Russo, J | 1 |
| Alston-Mills, B; Rivera, EM | 2 |
| Akagi, M; Inada, K; Kawano, I; Matsuo, S; Misumi, A; Yamashita, J | 1 |
| Dauvois, S; Labrie, F; Li, SM; Martel, C | 1 |
| Briatico, G; di Salle, E; Giudici, D; Ornati, G; Zaccheo, T | 1 |
| Clark, ER; Robinson, SP; Whitaker, EM; Zoltowski, JA | 1 |
| Hirose, M; Ito, N; Kurata, Y; Ohsawa, T; Shirai, T; Yamada, M | 1 |
| Bardasano, JL; Cos, S; Mediavilla, MD; Sánchez Barceló, EJ | 1 |
| Iino, Y; Ishikawa, H; Izuo, M; Takikawa, H | 2 |
| Dupuis, M; Gimotty, P; Russo, IH; Russo, J | 1 |
| Brown, J; Hyman, S; Mandal, A; Reese, IC; Siegler, R; Wong, DW | 1 |
| Dauvois, S; Labrie, F; Spinola, PG | 1 |
| Haaparanta, M; Kangas, L; Paul, R; Roeda, D; Sipilä, H | 1 |
| Bakker, GH; De Jong, FH; Foekens, JA; Klijn, JG; Portengen, H; Setyono-Han, B | 1 |
| Abou-Issa, H; Minton, JP; Moeschberger, M; Webb, TE | 1 |
| Bland, KI; Bryant, MS; Ellis, LM; Hogancamp, WE; Sitren, HS; Souba, WW; Wittliff, JL | 1 |
| Abou-el-Ela, SH; Bunce, OR; Carroll, RW; Farrell, RL; Prasse, KW; Wade, AE | 1 |
| Cohen, LA; el-Bayoumy, K; Nayini, J; Reddy, BS; Sugie, S | 1 |
| Hayes, C; Ip, C | 1 |
| Folléa, N; Labrie, F; Marchetti, B; Pelletier, G; Plante, M; Poyet, P; Spinola, PG | 1 |
| Coombes, RC; Gusterson, BA; Monaghan, P; Rudland, PS; Williams, JC | 1 |
| Bourget, L; Dinh, BL | 1 |
| Hanausek-Walaszek, M; Lang, RW; Walaszek, Z; Webb, TE | 1 |
| Dhar, R; Nakhasi, HL; Nieto, A; Qasba, PK | 1 |
| Chernov, MV; Kazarov, AR; Komarova, EA; Kriukova, IN | 1 |
| Barry, PA; Cardiff, RD; Dandekar, S; Gumerlock, PH; Meyers, FJ; Soong, MM; Young, LJ | 1 |
| Inui, T; Morii, S; Sakaida, N; Shikata, N; Tsubura, A | 1 |
| Abou-Issa, HM; Tejwani, GA; Vaswani, KK | 1 |
| Gaitens, PV; Ingleton, PM | 1 |
| Iversen, OH; Kolberg, A; Smith-Kielland, I; Stabursvik, A | 1 |
| Sulakhe, SJ | 1 |
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| Labrie, F; Marchetti, B; Spinola, PG | 1 |
| Adams, L; Choi, K; Doshi, RU; Karmali, RA | 1 |
| Bhatnagar, AS; Matter, A; Schieweck, K | 1 |
| Bollag, W; Hartmann, HR | 2 |
| Abou-Issa, HM; Duruibe, VA; Dwivedi, C; Larroya, S; Minton, JP; Webb, TE | 1 |
| Kusmartsev, SA; Ogreba, VI; Vasil'ev, NV | 1 |
| Alitalo, K; Sandberg, M; Vuorio, E; Vuorio, T; Wärri, A | 1 |
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| Abou-Issa, H; Duruibe, VA | 1 |
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| Hu, C; Li, SH; Liu, MS; Wang, XM; Zhang, HY | 1 |
| Basolo, F; Bistocchi, M; Sarnelli, R; Squartini, F | 1 |
| Cardiff, RD; Faulkin, LJ; Gardner, MB; Malone, RW; Mitchell, DJ; Morris, DW; Strange, R; Young, LJ | 1 |
| Breznik, T; Butel, JS; Cohen, JC; Gama-Sosa, MA; Medina, D | 1 |
| Cho-Chung, YS; Døskeland, SO; Ekanger, R; Haavik, J; Ogreid, D; Vintermyr, O | 1 |
| Klurfeld, DM; Kritchevsky, D; Ruggeri, BA | 1 |
| Butel, JS; Knepper, JE; Medina, D | 1 |
| Ip, C; Ip, MM; Sylvester, PW | 1 |
| Fletcher, WS; Jackson, CF; Miller, SH; Oyama, AA; Palmquist, MA; Swanson, JS; Wong, JH | 1 |
| Berger, MR; Schmähl, D | 2 |
| Boissonneault, GA; Elson, CE; Pariza, MW | 1 |
| Aylsworth, CF; Cullum, ME; Welsch, CW; Zile, MH | 1 |
| Rillema, JA | 1 |
| Ip, MM; Leung, KH | 1 |
| Burlaka, DP; Dasiukevich, OI; Gutnik, NS; Kartavova, NS | 2 |
| Berke, B; Choi, K; Cohen, LA; Numoto, S; Reddy, M; Weisburger, JH | 1 |
| Ip, C; White, G | 2 |
| Mitina, RL; Morozova, TM | 1 |
| Chang, N; Spaulding, TS; Tseng, MT | 2 |
| Hultborn, R; Jansson, I; Tveit, E; Weiss, L | 1 |
| Cullum, ME; DeHoog, JV; Roltsch, IA; Welsch, CW; Zile, MH | 1 |
| Buck, CL; Klurfeld, DM; Kritchevsky, D; Weber, MM | 1 |
| Boulanger, C; Conner, B; Lee, S; Rogers, AE | 1 |
| Barbacid, M | 1 |
| Fukushima, S; Hirose, M; Inoue, T; Ito, N; Masuda, A | 1 |
| Gould, MN; Werts, ED | 1 |
| Balmain, A; Brown, K; Quintanilla, M; Ramsden, M | 1 |
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| Hanausek-Walaszek, M; Minton, JP; Walaszek, Z; Webb, TE | 1 |
| Detrisac, CJ; May, CM; McCormick, DL; Thomas, CF | 1 |
| Kawasaki, T; Okamoto, R; Sakamoto, S | 1 |
| Brodie, AM; Santen, RJ | 1 |
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| Lee, SY; Rogers, AE | 1 |
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| Abou-Issa, H; James, A; McCabe, D; O'Dwyer, P; Sickle-Santanello, B; Woltering, E | 1 |
| Asch, BB; Bartley, JC; Guzman, RC; Imagawa, W; Nandi, S; Osborn, RC | 1 |
| Alster, JM; Clinton, SK; Imrey, PB; Nandkumar, S; Truex, CR; Visek, WJ | 1 |
| Kamioki, S | 1 |
| Cardiff, RD; Dandekar, S; Sukumar, S; Young, LJ; Zarbl, H | 1 |
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| Barron, ET; O'Higgins, NJ; Smyth, PP; Tobbia, I | 1 |
| Hilf, R; Roghmann, MC; Skinner, KA | 1 |
| Huggins, CB | 1 |
| Aylsworth, CF; O'Connor, DH; Sheffield, LG; Welsch, CW | 1 |
| Kothari, LS | 1 |
| Nagase, S; Takahashi, M | 1 |
| Maruyama, H; Moriguchi, M; Yamamoto, I | 1 |
| Brodack, JW; Carlson, KE; Katzenellenbogen, JA; Kiesewetter, DO; Kilbourn, MR; Mathias, CJ; Welch, MJ | 1 |
| Boylan, ES; Simpson, RW | 1 |
| Bendiug, GD; Grinevich, IuA; Kamenets, LIa; Nikol'skiĭ, IS | 1 |
| Fritz, NF; Jordan, VC; Ravdin, PM; Robinson, SP; van Beurden, M | 1 |
| Castanier, M; el Abed, A; Kerdelhue, B; Scholler, R | 1 |
| Boccardo, F; Cerruti, G; De Menech, R; Valenti, G; Zanardi, S | 1 |
| Eskander, ED; Gabriel, HF; Melhem, MF; Rao, KN | 1 |
| Holtzman, S; Machado, SG; Shellabarger, CJ; Stone, JP | 1 |
| Cundiff, KC; Ethier, SP | 1 |
| Jordan, VC; Robinson, SP | 1 |
| Chen, JJ; Kodell, RL | 1 |
| Depiante-Depaoli, M; Hliba, E; Pacheco-Rupil, B | 1 |
| Lemon, HM | 1 |
| Golotiuk, SI | 1 |
| Anisimov, V; Likhachev, A; Loktionov, A; Napalkov, N; Tomatis, L; Zabezhinski, M | 1 |
| Fukushima, S; Hirose, M; Ito, N; Masuda, A | 1 |
| Lahiri, P; Lahiri, T | 1 |
| Kort, WJ; Weijma, IM; Westbroek, DL | 1 |
| Holtzman, S | 1 |
| Boston, JL; Elson, CE; Gould, MN; Maltzman, TH; Tanner, MA | 1 |
| Hill, RW; Welsch, CW | 1 |
| Akagi, M; Fujino, N; Kimura, M; Shigaki, N; Takano, S | 1 |
| DeHoog, JV; O'Connor, DH; Welsch, CW | 2 |
| Anderson, JL; Munson, L; Stoewsand, GS | 1 |
| Andrushchak, LI; Khaetskaia, VI; Khaetskiĭ, IK; Nikitchenko, VV | 1 |
| Clark, ER; Mackay, D; Robinson, SP | 1 |
| Bunce, OR; Carroll, R; el-Ela, SH; Prasse, KW | 1 |
| Morozova, TM; Rau, VA; Sidorkina, OM | 1 |
| Carter, HW; Carter, JH; Meade, J | 1 |
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| Gebhard, RL; Pazik, JE; Sinha, DK | 1 |
| Hendry, LB; Muldoon, TG | 1 |
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| Inui, K; Komaki, K; Monden, Y; Morimoto, T; Sonoo, H | 1 |
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| Bollag, W; Teelmann, K | 1 |
| Gould, MN; Johnson, JA; Tanner, MA; Verma, AK | 1 |
| Brueggemeier, RW; Li, PK | 1 |
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| Berger, MR; Eibl, H; Engel, J; Hilgard, P; Schumacher, W; Stekar, J; Unger, C; Voegeli, R | 1 |
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| Duvigneau, C; Hölzel, F; Scherdin, U; Steffen, M | 1 |
| Abou-el-Ela, SH; Bunce, OR; Carroll, R; Dharwadkar, S; Prasse, KW; Wade, AE | 1 |
| Alster, JM; Clinton, SK; Imrey, PB; Simon, J; Visek, WJ | 1 |
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| Madigan, MJ; McCormick, DL; Moon, RC | 1 |
| Butel, JS; Halligan, R; Howard, C; Lane, HW; Medina, D; Shepherd, F | 1 |
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| Fujita, S; Fukuda, M; Hattori, T; Hosokawa, Y; Maekawa, J; Miyoshi, N; Nakanishi, K; Sugihara, H; Urata, Y | 1 |
| Holtzman, S; Meade, M; Shellabarger, CJ; Stone, JP | 1 |
| Berger, M; Prekajac, J; von Angerer, E | 1 |
| Akagi, M; Araki, K; Kimura, M; Nishimura, R; Sakamoto, K; Yamashita, J | 1 |
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| Johnson, IE; Mobbs, BG | 1 |
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59 review(s) available for 9,10-dimethyl-1,2-benzanthracene and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
Induced mammary cancer in rat models: pathogenesis, genetics, and relevance to female breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Estrogens; Female; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Quantitative Trait Loci; Rats; Rats, Sprague-Dawley | 2022 |
Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Carcinogenesis; Disease Models, Animal; DNA Damage; Female; Geriatrics; Humans; Longevity; Male; Mammary Neoplasms, Experimental; Mice; Rats, Sprague-Dawley; Research; Rodentia | 2019 |
Weight change patterns and breast cancer risk: a brief review and analysis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Animals; Body Mass Index; Breast Neoplasms; Caloric Restriction; Diet; Female; Humans; Life Style; Mammary Neoplasms, Experimental; Risk Factors; Weight Gain; Weight Loss | 2013 |
Efficacy of chemopreventive agents in mouse mammary gland organ culture (MMOC) model: a comprehensive review.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Chemoprevention; Female; Mammary Neoplasms, Experimental; Mice; Molecular Structure; Organ Culture Techniques; Treatment Outcome | 2008 |
Vanadium in the detection, prevention and treatment of cancer: the in vivo evidence.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Disease Models, Animal; Female; Glioblastoma; Humans; Male; Mammary Neoplasms, Experimental; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Organometallic Compounds; Rats; Trace Elements; Transplantation, Heterologous; Vanadium; Vanadium Compounds | 2010 |
Reduction of cancer risk by consumption of selenium-enriched plants: enrichment of broccoli with selenium increases the anticarcinogenic properties of broccoli.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Brassica; Colonic Neoplasms; Drug Interactions; Glutathione Peroxidase; Health Promotion; Humans; Mammary Neoplasms, Experimental; Neoplasms; Plants, Edible; Rats; Selenium | 2003 |
Mechanisms of mammary cancer chemoprevention by organoselenium compounds.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Breast Neoplasms; Clinical Trials as Topic; DNA Adducts; Humans; Mammary Neoplasms, Experimental; Organoselenium Compounds | 2004 |
Mechanisms mediating the effects of prepubertal (n-3) polyunsaturated fatty acid diet on breast cancer risk in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Diet; Fatty Acids, Unsaturated; Female; Humans; Mammary Neoplasms, Experimental; Rats | 2005 |
[Study of nutritional factors related to breast cancer prevention. Importance of animal models approaches].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carotenoids; Diet; Diet, Carbohydrate-Restricted; Disease Models, Animal; Energy Intake; Fatty Acids; Female; Glycine max; Iodine; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Rats; Retinoids; Risk Factors; Seaweed | 2005 |
Genistein and resveratrol: mammary cancer chemoprevention and mechanisms of action in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Administration, Oral; Adolescent; Age Factors; Animals; Antioxidants; Carcinogens; Cell Differentiation; Chemoprevention; Diet; Drug Administration Schedule; Drug Synergism; Estradiol; Female; Gene Expression Regulation; Genistein; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Molecular Structure; Pregnancy; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Resveratrol; Sexual Maturation; Soy Foods; Stilbenes; Wine | 2006 |
Relation of the neuroendocrine system to the development and growth of experimental mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylcholine; Animals; Breast Neoplasms; Dopamine; Estrogens; Ethamoxytriphetol; Female; Humans; Hypothalamus; Lactation; Levodopa; Male; Mammary Neoplasms, Experimental; Mice; Ovary; Pituitary Gland, Anterior; Pregnancy; Prolactin; Prolactin Release-Inhibiting Factors; Rats; Serotonin; Thyrotropin-Releasing Hormone | 1980 |
Differentiation of the mammary gland and susceptibility to carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abortion, Induced; Adenosine Triphosphatases; Aging; Animals; Antigens; Breast Neoplasms; Cell Cycle; Disease Susceptibility; DNA; DNA Repair; Epithelial Cells; Female; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Maternal Age; Parity; Pregnancy; Rats; Rats, Inbred Strains | 1982 |
[Stress and cancer].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Electroshock; Grief; Humans; Mammary Neoplasms, Experimental; Mice; Neoplasm Transplantation; Neoplasms; Rats; Social Isolation; Stress, Physiological; Stress, Psychological | 1984 |
Molecular and cellular basis of the mammary gland susceptibility to carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Binding Sites; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA Repair; Female; Hormones; In Vitro Techniques; Kinetics; Mammary Neoplasms, Experimental; Polycyclic Compounds; Rats; Rats, Inbred Strains | 1983 |
Laboratory studies to develop general principles for the adjuvant treatment of breast cancer with antiestrogens: problems and potential for future clinical applications.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Half-Life; Humans; Mammary Neoplasms, Experimental; Models, Biological; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen; Thiophenes | 1983 |
Selenium in carcinogenesis.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Cisplatin; Environmental Exposure; Epidemiologic Methods; Glutathione Peroxidase; Humans; Leukemia; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Neoplasms; Public Opinion; Selenium; United States | 1984 |
Basis of cellular autonomy in the susceptibility to carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Cycle; Cell Transformation, Neoplastic; Chorionic Gonadotropin; DNA; DNA Repair; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1983 |
Use of analogues of luteinizing hormone-releasing hormone for the treatment of cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Drug Therapy, Combination; Female; Gonadotropin-Releasing Hormone; Goserelin; Male; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Tamoxifen | 1982 |
Anti-oestrogen action in experimental breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Endometrium; Estrogen Antagonists; Estrogens; Female; Hypertrophy; Mammary Neoplasms, Experimental; Mitosis; Prolactin; Rats; Receptors, Estrogen; Tamoxifen; Uterus | 1980 |
Endocrine and cytostatic treatment of experimental mammary cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carmustine; Castration; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Ergolines; Female; Fluorouracil; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; Mice; Nitrosourea Compounds; Prednisolone; Rats; Tamoxifen; Vincristine | 1980 |
Influence of diet on mammary cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Diet; Dietary Carbohydrates; Dietary Fats; Female; Humans; Mammary Neoplasms, Experimental; Selenium; Vitamin A Deficiency | 1981 |
Effect of conjugated linoleic acid on carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimutagenic Agents; Cell Transformation, Neoplastic; Female; Gastrointestinal Neoplasms; Linoleic Acids; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred ICR; Rats; Rats, Inbred F344; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
Perinatal factors increase breast cancer risk.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antidepressive Agents; Breast Neoplasms; Cocarcinogenesis; Diet; Dietary Fats; Estradiol; Estrogens; Ethanol; Female; Handling, Psychological; Humans; Incidence; Liver Neoplasms, Experimental; Male; Mammary Neoplasms, Experimental; Maternal-Fetal Exchange; Mice; Mice, Transgenic; Personality; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Retrospective Studies; Risk Factors; Stress, Psychological; Transforming Growth Factor alpha | 1994 |
Pre-clinical and clinical treatment of breast cancer with antiprogestins.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Division; Clinical Trials as Topic; Drug Screening Assays, Antitumor; Estradiol; Female; Glucocorticoids; Gonadotropin-Releasing Hormone; Hormone Antagonists; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Pituitary-Adrenal System; Postmenopause; Progestins; Rats; Salvage Therapy; Tumor Cells, Cultured | 1994 |
Indole-3-carbinol. A novel approach to breast cancer prevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Breast Neoplasms; Carcinogens; Controlled Clinical Trials as Topic; Estradiol; Female; Humans; Indoles; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Rats; Rats, Inbred F344; Risk Factors; Rodentia; Tumor Cells, Cultured | 1995 |
Experimentally induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diet; Disease Models, Animal; Disease Progression; Disease Susceptibility; Female; Gonadal Steroid Hormones; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Radiation-Induced; Rats; Rats, Inbred F344; Rats, Sprague-Dawley | 1996 |
The relevance of preclinical models to the treatment of postmenopausal breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anastrozole; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Mammary Neoplasms, Experimental; Nitriles; Postmenopause; Rats; Triazoles | 1997 |
The use of transgenic animals in research.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Animals, Genetically Modified; Carcinogens, Environmental; Cell Transformation, Neoplastic; Codon; Genes, ras; Liver; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Knockout; Mitosis; Mutagenesis; Mutagenicity Tests; Mutagens; Neoplasms; Polymerase Chain Reaction; Rats; Sensitivity and Specificity; Transgenes | 1998 |
Magnetic fields and mammary cancer in rodents: a critical review and evaluation of published literature.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Biological Assay; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Disease Models, Animal; Electromagnetic Fields; Female; Fibroadenoma; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Rats | 2000 |
Transgenic mice reveal roles for TGFalpha and EGF receptor in mammary gland development and neoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Transformation, Neoplastic; ErbB Receptors; Female; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Pregnancy; Transforming Growth Factor alpha | 1997 |
Atlas and histologic classification of tumors of the rat mammary gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinoma, Intraductal, Noninfiltrating; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats | 2000 |
Mechanisms of hormonal prevention of breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Breast Neoplasms; Cell Division; DNA Damage; Estradiol; Estrogens; Female; Gene Expression Profiling; Genes, p53; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasms, Hormone-Dependent; Pregnancy; Progesterone; Rats; Rats, Inbred WF; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Reproductive History; Risk Factors | 2001 |
Chronic exposure to a GSM-like signal (mobile phone) does not stimulate the development of DMBA-induced mammary tumors in rats: results of three consecutive studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Dose-Response Relationship, Radiation; Environmental Exposure; Estrogens; Female; Life Tables; Mammary Neoplasms, Experimental; Models, Animal; Models, Biological; Neoplasms, Hormone-Dependent; Neoplasms, Radiation-Induced; Radio Waves; Rats; Rats, Sprague-Dawley; Safety; Telephone; Time Factors | 2002 |
Impeding estrogens and the etiology of breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies; Embryo Implantation; Estradiol; Estradiol Congeners; Estriol; Estrogen Antagonists; Female; Humans; Hydroxyestrones; Mammary Neoplasms, Experimental; Organ Size; Pregnancy; Rabbits; Rats; Receptors, Progesterone; Uterus | 1978 |
Endocrinology in cancer of the breast. Status and prospects.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Androgens; Animals; Breast Neoplasms; Carcinogens; Castration; Cyclic AMP; Cytosol; Estradiol; Estrogens; Female; Humans; Hypophysectomy; Mammary Neoplasms, Experimental; Megestrol; Mice; Neoplasm Regression, Spontaneous; Neoplasm Transplantation; Rats; Receptors, Cell Surface; Transplantation, Homologous | 1975 |
[Estrogen receptors in human and animal mammary gland tumors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Animals; Biological Transport, Active; Breast Neoplasms; Carcinoma; Carrier Proteins; Castration; Cell Nucleus; Estradiol; Estrogens; Female; Hexestrol; Hormones; Humans; Mammary Neoplasms, Experimental; Mice; Neoplasm Proteins; Oncogenic Viruses; Pregnancy; Protein Binding; Protein Conformation; Rats; Receptors, Cell Surface | 1975 |
Comparative effects of a series of prolactin inhibitors, 17beta-estradiol and 2alpha-methyldihydrotestosterone propionate, on growth of 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetonitriles; Androstanols; Animals; Breast Neoplasms; Bromocriptine; Drug Evaluation, Preclinical; Ergolines; Ergot Alkaloids; Estradiol; Female; Humans; Lisuride; Mammary Neoplasms, Experimental; Prolactin; Rats; Urea | 1977 |
[Successes of experimental oncology and problems of the study of the morphogenesis of tumors].
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Aflatoxins; Animals; Azoxymethane; Benzopyrenes; Brain Neoplasms; Carcinogens; Cricetinae; Dimethylhydrazines; Dogs; Esophageal Neoplasms; Ethionine; Ethylnitrosourea; Female; Hematopoietic System; Intestinal Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosamines; Nitroso Compounds; Nitrosoguanidines; o-Aminoazotoluene; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; Skin Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms | 1975 |
Voluntary exercise and experimental mammary cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred C3H; Neoplasm Metastasis; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Volition | 1992 |
Boundaries in mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Adult; Animals; Breast Neoplasms; Carcinogens; Carcinoma in Situ; Carcinoma, Intraductal, Noninfiltrating; Cocarcinogenesis; Disease Susceptibility; Female; Humans; Hyperplasia; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mast Cells; Middle Aged; Pregnancy; Proteoglycans; Rats; Rats, Inbred Strains | 1991 |
Genetic regulation of mammary carcinogenesis in the rat by susceptibility and suppressor genes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Carcinoma; Cell Differentiation; Chimera; Crosses, Genetic; DNA Damage; Epithelium; Female; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Graft Survival; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Phenotype; Rats; Rats, Inbred F344; Rats, Inbred WF; Transplantation, Heterotopic; Tumor Cells, Cultured | 1991 |
Mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Cocarcinogenesis; Disease Models, Animal; Disease Susceptibility; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Precancerous Conditions | 1991 |
Comparative study of human and rat mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast; Breast Neoplasms; Female; Humans; Immunohistochemistry; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Radiation Injuries, Experimental; Rats | 1990 |
Chemoprevention of mammary cancer by retinoids.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Drug Synergism; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasms, Hormone-Dependent; Organ Specificity; Rats; Retinoids; Skin Neoplasms; Species Specificity | 1990 |
Review of the effects of stress on cancer in laboratory animals: importance of time of stress application and type of tumor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascites; Carcinoma 256, Walker; Humans; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Oncogenic Viruses; Stress, Psychological | 1985 |
[The role of hormones in neoplastic transformation].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Epidermal Growth Factor; Hormones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Prolactin; Receptors, Cell Surface; Thyrotropin; Urethane | 1986 |
Early pathologic changes in experimental and human breast cancer: facts and comments.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast; Breast Neoplasms; Cell Transformation, Neoplastic; Female; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methylcholanthrene; Mice; Mice, Inbred BALB C; Models, Biological; Mosaicism; Precancerous Conditions; Pregnancy | 1986 |
Oncogenes and human cancer: cause or consequence?
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Chromosome Mapping; Gene Expression Regulation; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasms; Neoplasms, Experimental; Oncogenes; Proto-Oncogenes; Rats; Retroviridae; Skin Neoplasms | 1986 |
Aromatase in breast cancer and the role of aminoglutethimide and other aromatase inhibitors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Aminoglutethimide; Androgens; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Metabolic Clearance Rate; Middle Aged; Rats; Tamoxifen | 1986 |
Chemically-induced mammary gland tumors in rats: modulation by dietary fat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Dietary Fats; DNA Replication; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats | 1986 |
Fat-protein interaction, defined 2-generation studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Cell Transformation, Neoplastic; Cocarcinogenesis; Dietary Fats; Dietary Proteins; Disease Models, Animal; Eating; Epidemiologic Methods; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Prolactin; Thymidine | 1986 |
Role of acute caloric-restriction in murine tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Disease Models, Animal; Energy Intake; Food Deprivation; Hormones; Hypophysectomy; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Rats | 1986 |
Update on dietary fat and cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Age Factors; Animals; Cocarcinogenesis; Dietary Fats; Energy Intake; Epidemiologic Methods; Feeding Behavior; Female; Humans; Male; Mammary Neoplasms, Experimental; Middle Aged; Neoplasms; Sex Factors | 1986 |
[Oncogenes, their implications in cell growth, differentiation and carcinogenesis].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cell Transformation, Viral; Epidermal Growth Factor; Genes, Viral; Humans; Mammary Neoplasms, Experimental; Neoplasms; Platelet-Derived Growth Factor; Retroviridae; Transfection; Urinary Bladder Neoplasms | 1987 |
Laboratory models of breast cancer to aid the elucidation of antiestrogen action.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; Estrogen Antagonists; Estrogens; Mammary Neoplasms, Experimental; Methylnitrosourea; Prolactin; Receptors, Estrogen; Structure-Activity Relationship | 1987 |
From pathogenesis to hormone prevention of mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Contraceptive Agents, Female; Disease Models, Animal; Disease Susceptibility; Female; Hormones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Placental Hormones; Pregnancy | 1986 |
[A study model of estrogens and antiestrogens analysis].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Estrogen Antagonists; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasm Transplantation; Rats; Tamoxifen | 1987 |
Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: a review and tribute to Charles Brenton Huggins.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex Hormones; Animals; Antioxidants; Ascorbic Acid; Castration; Cocarcinogenesis; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Gonadal Steroid Hormones; Insulin; Male; Mammary Neoplasms, Experimental; Methylcholanthrene; Methylnitrosourea; Neoplasm Transplantation; Nucleotides, Cyclic; Pituitary Hormones, Anterior; Prostaglandins; Rats; Retinoids; Selenium; Thyroid Hormones; Vitamin E | 1985 |
Progestin action and progesterone receptor structure in human breast cancer: a review.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Affinity Labels; Animals; Antibodies, Monoclonal; Breast Neoplasms; Cells, Cultured; Chickens; Chromatography, DEAE-Cellulose; Estrenes; Female; Humans; Lipid Metabolism; Mammary Neoplasms, Experimental; Mifepristone; Molecular Weight; Neoplasms, Hormone-Dependent; Oviducts; Progestins; Rats; Receptor, Insulin; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone | 1985 |
5 trial(s) available for 9,10-dimethyl-1,2-benzanthracene and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
The Effect of (E)-1-(4'-aminophenyl)-3-phenylprop-2-en-1-one on MicroRNA-18a, Dicer1, and MMP-9 Expressions against DMBA-Induced Breast Cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Carcinogens; Cell Proliferation; Chalcone; DEAD-box RNA Helicases; Female; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 9; Mice; MicroRNAs; Propiophenones; Rats, Sprague-Dawley; Ribonuclease III; Tumor Cells, Cultured | 2020 |
Chemoendocrine therapy in advanced breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Diethylstilbestrol; Drug Therapy, Combination; Female; Fluorouracil; Humans; Mammary Neoplasms, Experimental; Menopause; Neoplasms, Hormone-Dependent; Random Allocation; Rats; Rats, Inbred Strains; Receptors, Estrogen | 1981 |
Effect of dehydroepiandrosterone on bone mass, serum lipids, and dimethylbenz(a)anthracene-induced mammary carcinoma in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaline Phosphatase; Animals; Body Weight; Bone Density; Calcium; Carcinogens; Cholesterol; Dehydroepiandrosterone; Dihydrotestosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Female; Femur; Lipids; Lumbar Vertebrae; Mammary Neoplasms, Experimental; Phosphorus; Rats; Rats, Sprague-Dawley; Testosterone; Triglycerides | 1997 |
Aromatase in breast cancer and the role of aminoglutethimide and other aromatase inhibitors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Aminoglutethimide; Androgens; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Metabolic Clearance Rate; Middle Aged; Rats; Tamoxifen | 1986 |
[Synergistic action of lentinan (LNT) with endocrine therapy of breast cancer in rats and humans].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Adult; Animals; Breast Neoplasms; Combined Modality Therapy; Drug Synergism; Female; Humans; Lentinan; Mammary Neoplasms, Experimental; Middle Aged; Ovariectomy; Polysaccharides; Random Allocation; Rats; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1987 |
1574 other study(ies) available for 9,10-dimethyl-1,2-benzanthracene and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
Protective effects of hesperidin through attenuation of Ki67 expression against DMBA-induced breast cancer in female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Carcinogens; Chemoprevention; Doxorubicin; Female; Hesperidin; Ki-67 Antigen; Mammary Neoplasms, Experimental; Rats; Rats, Wistar | 2021 |
Neferine Inhibits 7,12-Dimethylbenz(a)anthracene-Induced Mammary Tumorigenesis by Suppression of Cell Proliferation and Induction of Apoptosis via Modulation of the PI3K/AKT/NF-κB Signaling Pathway.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzylisoquinolines; Body Weight; Carcinogens; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Lipid Peroxidation; Mammary Neoplasms, Experimental; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction | 2021 |
Oral administration of tartrazine (E102) accelerates the incidence and the development of 7,12-dimethylbenz(a) anthracene (DMBA)-induced breast cancer in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; alpha-Fetoproteins; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma; Estradiol; Female; Mammary Neoplasms, Experimental; Mucin-1; Organ Size; Oxidative Stress; Rats; Rats, Wistar; Tartrazine; Tumor Burden | 2021 |
Classification of rat mammary carcinoma with large scale in vivo microwave measurements.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Electric Conductivity; Electrodiagnosis; Female; Machine Learning; Mammary Neoplasms, Experimental; Microwaves; Predictive Value of Tests; Rats, Sprague-Dawley; Reproducibility of Results | 2022 |
Salvadora persica attenuates DMBA-induced mammary cancer through downregulation oxidative stress, estrogen receptor expression and proliferation and augmenting apoptosis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Proliferation; Down-Regulation; Female; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Oxidative Stress; Plant Extracts; Random Allocation; Rats; Rats, Wistar; Receptors, Estrogen; Salvadoraceae; Xenograft Model Antitumor Assays | 2022 |
Effects of Pubertal Exposure to Butyl Benzyl Phthalate, Perfluorooctanoic Acid, and Zeranol on Mammary Gland Development and Tumorigenesis in Rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Caprylates; Carcinogenesis; Cell Transformation, Neoplastic; Endocrine Disruptors; Female; Fluorocarbons; Hormones; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Phthalic Acids; Rats; Rats, Sprague-Dawley; Zeranol | 2022 |
Investigation of the Anticancer Effect of
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Caco-2 Cells; Computer Simulation; Drug Evaluation, Preclinical; Female; Fishes; Humans; Mammary Neoplasms, Experimental; Models, Molecular; Molecular Docking Simulation; Molecular Targeted Therapy; Organophosphonates; Plant Extracts; Quinolines; Rats; Thymidylate Synthase | 2022 |
Effects of melatonin and metformin in preventing lysosome-induced autophagy and oxidative stress in rat models of carcinogenesis and the impact of high-fat diet.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Autophagy; Carcinogenesis; Diet, High-Fat; Female; Humans; Lysosomes; Mammary Neoplasms, Experimental; Melatonin; Metformin; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2022 |
Chemopreventive Effect of Dietary Maranta arundinacea L. Against DMBA-Induced Mammary Cancer in Sprague Dawley Rats Through the Regulation of Autophagy Expression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Autophagy; Breast Neoplasms; Diet; Female; Humans; Mammary Neoplasms, Experimental; Marantaceae; Rats; Rats, Sprague-Dawley | 2022 |
Zingiberene exerts chemopreventive activity against 7,12-dimethylbenz(a)anthracene-induced breast cancer in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Antioxidants; Carcinogens; Corn Oil; Female; Mammary Neoplasms, Experimental; Monocyclic Sesquiterpenes; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Transaminases | 2022 |
CEG-AgNPs Ameliorates DMBA-Induced Mammary Carcinogenicity by Alleviating Cytokines Expression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Carcinoma; Cytokines; Female; Humans; Mammary Neoplasms, Experimental; Mice; Rats | 2022 |
Canagliflozin interrupts mTOR-mediated inflammatory signaling and attenuates DMBA-induced mammary cell carcinoma in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Canagliflozin; Carcinoma; Caspase 1; Female; Inflammation Mediators; Ki-67 Antigen; Mammary Neoplasms, Experimental; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley; Signal Transduction; TOR Serine-Threonine Kinases | 2022 |
Herbal Honey Preparations of Curcuma Xanthorriza and Black Cumin Protect against Carcinogenesis through Antioxidant and Immunomodulatory Activities in Sprague Dawley (SD) Rats Induced with Dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Antioxidants; Carcinogenesis; Carcinogens; Curcuma; Honey; Humans; Mammary Neoplasms, Experimental; Nigella sativa; Rats; Rats, Sprague-Dawley | 2023 |
Anticancer role of mango (Mangifera indica L.) peel and seed kernel extracts against 7,12- dimethylbenz[a]anthracene-induced mammary carcinogenesis in female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Carcinogenesis; Caspase 3; Female; Glutathione; Mammary Neoplasms, Experimental; Mangifera; Oxidoreductases; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2023 |
Protective Effects of Pelargonidin against DMBA-Induced Mammary Tumorigenesis in BALB/c Mice through Reduced Oxidative Stress and Lipid Anomalies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Lipids; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Oxidative Stress; Tamoxifen | 2023 |
Zingerone induced caspase-dependent apoptosis in MCF-7 cells and prevents 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in experimental rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Biotransformation; Blotting, Western; Carcinogens; Caspases; Guaiacol; Humans; Lipid Peroxidation; Mammary Neoplasms, Experimental; MCF-7 Cells; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2019 |
Conjugated Linoleic Acid Isomers Affect Profile of Lipid Compounds and Intensity of Their Oxidation in Heart of Rats with Chemically-Induced Mammary Tumors-Preliminary Study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Supplements; Female; Heart; Heart Diseases; Isomerism; Linoleic Acids, Conjugated; Lipid Peroxidation; Mammary Neoplasms, Experimental; Oxidation-Reduction; Rats | 2019 |
A Multistage Murine Breast Cancer Model Reveals Long-Lived Premalignant Clones Refractory to Parity-Induced Protection.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Clone Cells; Disease Progression; Epithelial Cells; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Mutation; Parity; Pregnancy; Proto-Oncogene Proteins p21(ras); Time Factors; Wnt Signaling Pathway; Wnt1 Protein | 2020 |
A bright NIR-II fluorescent probe for breast carcinoma imaging and image-guided surgery.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biocompatible Materials; Breast Neoplasms; Female; Fluorescent Dyes; Humans; Infrared Rays; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Rats; Rats, Sprague-Dawley | 2019 |
Daucosterol from Crateva adansonii DC (Capparaceae) reduces 7,12-dimethylbenz(a)anthracene-induced mammary tumors in Wistar rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Capparaceae; Carcinogens; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Molecular Structure; Plant Bark; Rats; Rats, Wistar; Sitosterols | 2020 |
Nobiletin Attenuates Cell Proliferation by Modulating the Activating Protein-1 Signaling Pathway in 7,12-Dimethylbenz[a]anthracene-Induced Mammary Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Breast Neoplasms; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Female; Flavones; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Signal Transduction; Transcription Factor AP-1 | 2020 |
Amelioration of cyclophosphamide-induced myelosuppression during treatment to rats with breast cancer through low-intensity pulsed ultrasound.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Blood Cell Count; Bone Marrow; Carcinogens; Cyclophosphamide; Disease Models, Animal; Female; Femur; Hematopoiesis; Humans; Injections, Intraperitoneal; Leukopenia; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Ultrasonic Therapy | 2020 |
Hybrid Quinazoline 1,3,5-Triazines as Epidermal Growth Factor Receptor (EGFR) Inhibitors with Anticancer Activity: Design, Synthesis, and Computational Study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; ErbB Receptors; Female; Humans; Mammary Neoplasms, Experimental; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Triazines; Tumor Cells, Cultured | 2021 |
The combined effect of pomegranate extract and tangeretin on the DMBA-induced breast cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; bcl-2-Associated X Protein; Carcinogens; Chemoprevention; Drug Combinations; Estrogen Receptor alpha; Female; Flavones; Ki-67 Antigen; Mammary Neoplasms, Experimental; NF-kappa B; Plant Extracts; Pomegranate; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53 | 2021 |
A Step Forward in Breast Cancer Research: From a Natural-Like Experimental Model to a Preliminary Photothermal Approach.
Topics: 5-Methylcytosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Female; Gold; Hyperthermia, Induced; Mammary Neoplasms, Experimental; Metal Nanoparticles; Models, Theoretical; Rats; Rats, Sprague-Dawley | 2020 |
Attenuated TGFB signalling in macrophages decreases susceptibility to DMBA-induced mammary cancer in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Susceptibility; Disease-Free Survival; Epithelial Cells; Estrous Cycle; Female; Humans; Inflammation; Macrophages; Mammary Glands, Animal; Mammary Glands, Human; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Receptor, Transforming Growth Factor-beta Type I; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta1 | 2021 |
Chronic stress caused by maternal separation is a possible risk factor for the development of 7,12-dimethyl benzo anthracene-induced breast tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Female; Mammary Neoplasms, Experimental; Maternal Deprivation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Risk Factors | 2021 |
MPA/DMBA-driven mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinoma; Female; Humans; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL | 2021 |
Dimethylbenz(a)anthracene-induced mammary tumorigenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Carcinogenesis; Carcinogens; Mammary Neoplasms, Experimental; Mice | 2021 |
Preventive Effect of Combined
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ellagic Acid; Mammary Neoplasms, Experimental; Plant Extracts; Rats; Terminalia; TOR Serine-Threonine Kinases; Zingiber officinale | 2022 |
Mangiferin Inhibits Inflammation and Cell Proliferation, and Activates Proapoptotic Events via NF-κB Inhibition in DMBA-Induced Mammary Carcinogenesis in Rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Carcinogens; Cell Proliferation; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; NF-kappa B; Rats, Sprague-Dawley; Xanthones | 2021 |
vHTS and 3D-QSAR for the Identification of Novel Phyto-inhibitors of Farnesyltransferase: Validation of Ascorbic Acid inhibition of Farnesyltransferase in an Animal Model of Breast Cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anacardiaceae; Animals; Antineoplastic Agents, Phytogenic; Ascorbic Acid; Carcinogens; Curcuma; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Farnesyltranstransferase; Female; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Mammary Neoplasms, Experimental; Molecular Docking Simulation; Quantitative Structure-Activity Relationship; Rats; Taraxacum | 2021 |
A Method to Pre-Screen Rat Mammary Gland Whole-Mounts Prior To RNAscope.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Intraductal, Noninfiltrating; Disease Models, Animal; Female; Gene Expression Profiling; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; RNA; Tissue Preservation | 2021 |
The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiotensin II Type 1 Receptor Blockers; Animals; Biopsy; Breast Neoplasms; Carcinogenesis; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Cell Proliferation; Disease Progression; Female; Humans; Immunohistochemistry; Interleukin-6; Losartan; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Neoplasm Invasiveness; Phosphorylation; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; STAT3 Transcription Factor; Tumor Burden; Tumor Necrosis Factor-alpha; Up-Regulation | 2017 |
Early-in-life dietary zinc deficiency and supplementation and mammary tumor development in adulthood female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Diet; Dietary Supplements; Female; Humans; Male; Mammary Glands, Human; Mammary Neoplasms, Experimental; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Zinc | 2017 |
Anti-Inflammatory Mechanism Involved in Pomegranate-Mediated Prevention of Breast Cancer: the Role of NF-κB and Nrf2 Signaling Pathways.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Apoptosis; Cell Transformation, Neoplastic; Cyclooxygenase 2; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; I-kappa B Kinase; Lythraceae; Mammary Neoplasms, Experimental; NF-E2-Related Factor 2; NF-kappa B; Plant Preparations; Rats; Signal Transduction | 2017 |
Effect of allyl isothiocyanate on NF-κB signaling in 7,12-dimethylbenz(a)anthracene and N-methyl-N-nitrosourea-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Female; Food Preservatives; Gene Expression Regulation, Neoplastic; Isothiocyanates; Mammary Neoplasms, Experimental; Methylnitrosourea; NF-kappa B; Rats; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Preventive effect of berberine against DMBA-induced breast cancer in female Sprague Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Berberine; Carcinogens; Female; Mammary Neoplasms, Experimental; Random Allocation; Rats; Rats, Sprague-Dawley; Treatment Outcome; Tumor Burden | 2017 |
Allyl isothiocyanate, a potent chemopreventive agent targets AhR/Nrf2 signaling pathway in chemically induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Transformation, Neoplastic; Female; Isothiocyanates; Mammary Neoplasms, Experimental; Neoplasm Proteins; NF-E2-Related Factor 2; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Signal Transduction | 2018 |
Epigallocatechin-3-Gallate: The Prospective Targeting of Cancer Stem Cells and Preventing Metastasis of Chemically-Induced Mammary Cancer in Rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Catechin; Female; Mammary Neoplasms, Experimental; Neoplastic Stem Cells; Rats; Rats, Sprague-Dawley | 2017 |
Early Exposure to a High Fat/High Sugar Diet Increases the Mammary Stem Cell Compartment and Mammary Tumor Risk in Female Mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adiponectin; Animals; Body Weight; Carcinogenesis; Diet, Fat-Restricted; Diet, High-Fat; Dietary Sugars; Feeding Behavior; Female; Insulin Resistance; Insulin-Like Growth Factor I; Lactation; Leptin; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Maternal Exposure; Mice; Mice, Inbred SENCAR; Obesity; Risk Factors; Stem Cells; Time Factors | 2017 |
The effects of ω-6 and ω-3 fatty-acids on early stages of mice DMBA submandibular glands tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Immunohistochemistry; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Submandibular Gland | 2017 |
The effect of zinc and melatonin supplementation on immunity parameters in breast cancer induced by DMBA in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Supplements; Female; Mammary Neoplasms, Experimental; Melatonin; Rats; Rats, Sprague-Dawley; Rats, Wistar; Zinc | 2018 |
Blood flow, volume and arterio-venous passages in induced mammary tumours of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arteries; Autoradiography; Blood Flow Velocity; Blood Volume; Blood Volume Determination; Female; Mammary Neoplasms, Experimental; Neovascularization, Pathologic; Perfusion Imaging; Pulmonary Circulation; Rats, Sprague-Dawley; Regional Blood Flow; Time Factors; Tumor Microenvironment; Veins | 2018 |
7,8-Dihydroxycoumarin exerts antitumor potential on DMBA-induced mammary carcinogenesis by inhibiting ERα, PR, EGFR, and IGF1R: involvement of MAPK1/2-JNK1/2-Akt pathway.
Topics: 17-Hydroxysteroid Dehydrogenases; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Aromatase; Biomarkers, Tumor; Carcinogens; Cell Proliferation; Cytokines; Dose-Response Relationship, Drug; ErbB Receptors; Estrogen Receptor alpha; Female; Humans; Inflammation Mediators; Ki-67 Antigen; Mammary Neoplasms, Experimental; MCF-7 Cells; Proliferating Cell Nuclear Antigen; Protein Kinases; Rats, Sprague-Dawley; Receptor, IGF Type 1; Receptors, Progesterone; Umbelliferones | 2018 |
Genetic polymorphisms and protein expression of P53 and BRCA1 in preneoplastic and neoplastic rat mammary glands.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; BRCA1 Protein; Cell Cycle; Cell Nucleus; Cytoplasm; Disease Progression; Exons; Female; Gene Expression Regulation, Neoplastic; Genetic Variation; Mammary Neoplasms, Experimental; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Precancerous Conditions; Protein Transport; Rats; Tumor Suppressor Protein p53 | 2018 |
Euterpe oleracea extract inhibits tumorigenesis effect of the chemical carcinogen DMBA in breast experimental cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carcinogens; Cell Line, Tumor; Euterpe; Female; Humans; Mammary Neoplasms, Experimental; Plant Extracts; Rats; Rats, Wistar | 2018 |
A trisubstituted pyrazole derivative reduces DMBA-induced mammary tumor growth in rats by inhibiting estrogen receptor-α expression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Molecular Docking Simulation; Pyrazoles; Rats; Rats, Sprague-Dawley | 2018 |
Taxifolin binds with LXR (α & β) to attenuate DMBA-induced mammary carcinogenesis through mTOR/Maf-1/PTEN pathway.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Liver X Receptors; MafB Transcription Factor; Mammary Neoplasms, Experimental; Molecular Docking Simulation; Oncogene Proteins; Protein Binding; PTEN Phosphohydrolase; Quercetin; Rats, Sprague-Dawley; Signal Transduction; TOR Serine-Threonine Kinases | 2018 |
Therapeutic effect of simvastatin on DMBA-induced breast cancer in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Aryldialkylphosphatase; Dinoprostone; Dose-Response Relationship, Drug; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Malondialdehyde; Mammary Neoplasms, Experimental; Mice; Mucin-1; Oxidative Stress; Simvastatin; Tamoxifen | 2019 |
DMBA promotes ErbB2‑mediated carcinogenesis via ErbB2 and estrogen receptor pathway activation and genomic instability.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Female; Genomic Instability; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Receptor, ErbB-2; Receptors, Estrogen; Tumor Cells, Cultured | 2018 |
Biochemical studies evaluating the chemopreventive potential of brucine in chemically induced mammary carcinogenesis of rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Chemoprevention; Dose-Response Relationship, Drug; Female; Lipid Metabolism; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Oxidative Stress; Rats, Sprague-Dawley; Strychnine | 2019 |
Taurine abrogates mammary carcinogenesis through induction of apoptosis in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; bcl-2-Associated X Protein; Carcinogens; Caspases; Disease Progression; Female; Mammary Neoplasms, Experimental; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley; Taurine; Tumor Suppressor Protein p53 | 2018 |
Cetirizine and thalidomide synergistically inhibit mammary tumorigenesis and angiogenesis in 7,12-dimethylbenz(a)anthracene-treated rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Apoptosis; Blotting, Western; Cell Proliferation; Cetirizine; Drug Synergism; Female; Fibroblast Growth Factor 2; Mammary Neoplasms, Experimental; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Thalidomide; Vascular Endothelial Growth Factor A | 2018 |
Phytol as an anticarcinogenic and antitumoral agent: An in vivo study in swiss mice with DMBA-Induced breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Comet Assay; Cyclophosphamide; DNA Damage; DNA Repair; Drug Administration Schedule; Female; Humans; Ki-67 Antigen; Leukocytes, Mononuclear; Locomotion; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Phytol | 2019 |
Effects of Jaeumkanghwa-tang on tamoxifen responsiveness in preclinical ER+ breast cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cytokines; Drug Resistance, Neoplasm; Endometrium; Estrogen Antagonists; Female; Forkhead Transcription Factors; Humans; Mammary Neoplasms, Experimental; Medicine, East Asian Traditional; Neoplasm Recurrence, Local; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tamoxifen; Transforming Growth Factor beta1; Tumor Microenvironment | 2019 |
A Novel Animal Model of Induced Breast Precancerous Lesion in Tree Shrew.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Synergism; Estrogen Receptor alpha; Female; Keratin-5; Keratin-6; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Precancerous Conditions; Receptor, ErbB-2; Receptors, Progesterone; Tupaiidae | 2019 |
3, 3'-Diindolylmethane-encapsulated chitosan nanoparticles accelerate molecular events during chemical carcinogen-induced mammary cancer in Sprague Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Carcinogens; Chitosan; Cyclin D1; Female; Gene Expression Regulation, Neoplastic; Indoles; Mammary Neoplasms, Experimental; Nanoparticles; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley | 2019 |
Synergistic efficacy of RLIP inhibition and 2'-hydroxyflavanone against DMBA-induced mammary carcinogenesis in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; CDC2 Protein Kinase; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Flavanones; GTPase-Activating Proteins; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred SENCAR; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt | 2019 |
Examining the Role of Nuclear Receptors During In Vivo Chemical-Mediated Breast Tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogenicity Tests; Carcinogens; Female; Mammary Neoplasms, Experimental; Mice; Receptors, Cytoplasmic and Nuclear | 2019 |
Dose-dependent chemopreventive effects of citronellol in DMBA-induced breast cancer among rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acyclic Monoterpenes; Animals; Anticarcinogenic Agents; Female; Humans; Liver; Mammary Glands, Human; Mammary Neoplasms, Experimental; Rats, Sprague-Dawley; Tumor Burden | 2019 |
Is there any potential anticancer effect of raloxifene and fluoxetine on DMBA-induced rat breast cancer?
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Carcinogens; Enzyme-Linked Immunosorbent Assay; Female; Fluoxetine; Mammary Neoplasms, Experimental; Raloxifene Hydrochloride; Rats; Rats, Wistar; Weight Gain | 2019 |
Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Cell Proliferation; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Oleanolic Acid; Rats; Rats, Sprague-Dawley | 2013 |
High susceptibility of heterozygous (+/fa) lean Zucker rats to 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogenesis; Cell Differentiation; Corn Oil; Diet; Eating; Female; Heterozygote; Leptin; Mammary Neoplasms, Experimental; MAP Kinase Signaling System; Rats; Rats, Zucker; Receptors, Estrogen; Receptors, Leptin; Survival Rate | 2013 |
Regulator of G protein signaling 6 is a novel suppressor of breast tumor initiation and progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Disease Progression; DNA Damage; Epithelial Cells; ErbB Receptors; Female; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Receptors, Estrogen; RGS Proteins; Signal Transduction; Tumor Suppressor Protein p53 | 2013 |
Modulating effects of hesperidin on key carbohydrate-metabolizing enzymes, lipid profile, and membrane-bound adenosine triphosphatases against 7,12-dimethylbenz(a)anthracene-induced breast carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenosine Triphosphatases; Animals; Carbohydrate Metabolism; Carcinogens; Cell Membrane; Female; Hesperidin; Lipid Metabolism; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 2014 |
Inhibitory effects of Tualang Honey on experimental breast cancer in rats: a preliminary study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Blotting, Western; Carcinogens; Cell Proliferation; Female; Honey; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A | 2013 |
Experimental hypothyroidism increases apoptosis in dimethylbenzanthracene-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adipokines; Animals; Apoptosis; Body Composition; Carcinogens; Cell Proliferation; Estradiol; Female; Hypothyroidism; Leptin; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Progesterone; Prolactin; Rats; Rats, Sprague-Dawley | 2013 |
Loss of PPARγ expression in mammary secretory epithelial cells creates a pro-breast tumorigenic environment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; bcl-2-Associated X Protein; Epithelial Cells; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Knockout; PPAR gamma; PTEN Phosphohydrolase | 2014 |
Characterization of synergistic anti-cancer effects of docosahexaenoic acid and curcumin on DMBA-induced mammary tumorigenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Transformation, Neoplastic; Cluster Analysis; Curcumin; Diet; Docosahexaenoic Acids; Drug Synergism; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Inhibitor of Apoptosis Proteins; Mammary Neoplasms, Experimental; Mice; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Serpins; Survivin; Tumor Burden; Tumor Microenvironment | 2013 |
Alteration in apoptosis and cell cycle by celecoxib and/or fish oil in 7,12-dimethyl benzene (α) anthracene-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Calcium; Celecoxib; Cell Cycle; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Epithelial Cells; Fatty Acids, Omega-3; Female; Fish Oils; Flow Cytometry; Immunohistochemistry; Keratin-19; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Proto-Oncogene Proteins c-myc; Pyrazoles; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfonamides; Tumor Suppressor Protein p53 | 2013 |
Quercetin attenuates oxidative stress in the blood plasma of rats bearing DMBA-induced mammary cancer and treated with a combination of doxorubicin and docetaxel.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Doxorubicin; Female; Mammary Neoplasms, Experimental; Oxidative Stress; Quercetin; Rats; Rats, Sprague-Dawley; Taxoids | 2013 |
Simultaneous disruption of estrogen receptor and Wnt/β-catenin signaling is involved in methyl amooranin-mediated chemoprevention of mammary gland carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Catenin; Carcinogenesis; Cell Transformation, Neoplastic; Chemoprevention; Cyclin D1; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Kidney; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Triterpenes; Wnt Proteins; Wnt Signaling Pathway | 2013 |
Effects of dietary apigenin on tumor latency, incidence and multiplicity in a medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced breast cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apigenin; Breast Neoplasms; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hormone Replacement Therapy; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Postmenopause; Rats; Rats, Sprague-Dawley | 2013 |
Phytochemical analysis and anticancer capacity of Shemamruthaa, a herbal formulation against DMBA- induced mammary carcinoma in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Hibiscus; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Phyllanthus; Plant Extracts; Rats; Rats, Sprague-Dawley | 2013 |
Improving discrimination in the grading of rat mammary tumors using two-dimensional mapping of histopathological observations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Discriminant Analysis; Female; Mammary Neoplasms, Experimental; Neoplasm Grading; Principal Component Analysis; Rats; Rats, Sprague-Dawley | 2014 |
Exposure to excess estradiol or leptin during pregnancy increases mammary cancer risk and prevents parity-induced protective genomic changes in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Biomarkers, Tumor; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Estradiol; Estrogens; Female; Gene Expression Profiling; Genomics; Immunoenzyme Techniques; Leptin; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Parity; Pregnancy; Pregnancy Complications, Neoplastic; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger | 2013 |
Copper and resveratrol attenuates serum catalase, glutathione peroxidase, and element values in rats with DMBA-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antidotes; Antioxidants; Carcinogens; Catalase; Copper; Copper Sulfate; Female; Glutathione Peroxidase; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2013 |
Chemotherapeutic effect of tangeretin, a polymethoxylated flavone studied in 7, 12-dimethylbenz(a)anthracene induced mammary carcinoma in experimental rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; alpha-Fetoproteins; Animals; Antineoplastic Agents, Phytogenic; Carcinoembryonic Antigen; Carcinoma, Ductal, Breast; Drug Screening Assays, Antitumor; Female; Flavones; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Metabolic Detoxication, Phase I; Mucin-1; Oxidative Stress; Rats; Rats, Wistar; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Thiobarbituric Acid Reactive Substances; Tumor Burden | 2014 |
Trianthema portulacastrum Linn. exerts chemoprevention of 7,12-dimethylbenz(a)anthracene-induced mammary tumorigenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aizoaceae; Animals; bcl-2-Associated X Protein; Carcinogens; Cell Proliferation; Dietary Supplements; Humans; Male; Mammary Neoplasms, Experimental; Phytotherapy; Plants, Medicinal; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Up-Regulation; Wnt Signaling Pathway | 2014 |
Folic acid supplementation promotes mammary tumor progression in a rat model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; bcl-2-Associated X Protein; Dietary Supplements; Disease Progression; Female; Folic Acid; Gene Expression; Humans; Mammary Neoplasms, Experimental; Neoplasm Proteins; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Tumor Burden | 2014 |
Establishment of novel rat models for premalignant breast disease.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Diseases; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 2014 |
Effects of parity and serum prolactin levels on the incidence and regression of DMBA-induced tumors in OFA hr/hr rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Neoplasm Proteins; Parity; Pregnancy; Prolactin; Rats | 2014 |
Tangeretin, a citrus pentamethoxyflavone, exerts cytostatic effect via p53/p21 up-regulation and suppresses metastasis in 7,12-dimethylbenz(α)anthracene-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Female; Flavones; Gonadal Steroid Hormones; Mammary Neoplasms, Experimental; Neoplasm Metastasis; Polymerase Chain Reaction; Proto-Oncogene Proteins p21(ras); Rats; Rats, Wistar; Tumor Suppressor Protein p53; Up-Regulation | 2014 |
Anti-tumorigenic effect of nano formulated peptide pACC1 by diminishing de novo lipogenisis in DMBA induced mammary carcinoma rat model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chemistry, Pharmaceutical; Chitosan; Female; Lipogenesis; Mammary Neoplasms, Experimental; Nanoparticles; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2014 |
Preventive effects of probiotic bacteria Lactobacillus plantarum and dietary fiber in chemically-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cytokines; Diet; Dietary Fiber; Disease Models, Animal; Female; Inulin; Lactobacillus plantarum; Mammary Neoplasms, Experimental; Neoplasm Invasiveness; Neoplasm Staging; Probiotics; Rats; T-Lymphocyte Subsets | 2014 |
Decreased expression of stem cell markers by simvastatin in 7,12-dimethylbenz(a)anthracene (DMBA)-induced breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Biomarkers; Biomarkers, Tumor; Carcinogens; Disease Progression; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Mammary Neoplasms, Experimental; Necrosis; Neoplastic Stem Cells; Rats; Rats, Sprague-Dawley; Simvastatin | 2015 |
Antitumor efficacy of tangeretin by targeting the oxidative stress mediated on 7,12-dimethylbenz(a) anthracene-induced proliferative breast cancer in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Biomarkers; Body Weight; Carcinoembryonic Antigen; Carcinogens; Dose-Response Relationship, Drug; Female; Flavones; Mammary Neoplasms, Experimental; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2015 |
PTEN/PIK3CA genes are frequently mutated in spontaneous and medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced mammary tumours of tree shrews.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Ductal, Breast; Carcinoma, Papillary; Disease Models, Animal; Estrogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mutation; Papilloma, Intraductal; Phosphatidylinositol 3-Kinase; Progesterone; PTEN Phosphohydrolase; Random Allocation; Receptors, Estrogen; Receptors, Progesterone; Tupaiidae | 2014 |
Suppression of 7,12-dimethylbenz(a)anthracene-induced mammary tumorigenesis by glyceollins.
Topics: 8-Hydroxy-2'-Deoxyguanosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cytochrome P-450 CYP1A1; Deoxyguanosine; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mucin-1; NF-E2-Related Factor 2; Pterocarpans | 2015 |
Chemopreventive effects of hydatid disease on experimental breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Echinococcosis; Echinococcus granulosus; Female; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Rats; Rats, Wistar | 2015 |
Dose response chemopreventive potential of allyl isothiocyanate against 7,12-dimethylbenz(a)anthracene induced mammary carcinogenesis in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Dose-Response Relationship, Drug; Female; Isothiocyanates; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 2015 |
D-pinitol mitigates tumor growth by modulating interleukins and hormones and induces apoptosis in rat breast carcinogenesis through inhibition of NF-κB.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Biomarkers, Tumor; Cytokines; Female; Gene Expression Regulation, Neoplastic; Hormones; Immunoglobulins; Inositol; Interleukins; Lipid Metabolism; Mammary Neoplasms, Experimental; NF-kappa B; Rats, Sprague-Dawley | 2015 |
Opposing roles for mammary epithelial-specific PPARγ signaling and activation during breast tumour progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; BRCA1 Protein; Cytokines; Disease Progression; Epithelial Cells; Female; Gene Deletion; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice, Knockout; Models, Biological; Organ Specificity; PPAR gamma; Signal Transduction; Tumor Burden | 2015 |
Erythrocyte Protoporphyrin Fluorescence as a Biomarker to Monitor the Anticancer Effect of Semecarpus Anacardium in DMBA Induced Mammary Carcinoma Rat Model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Biomarkers; Carcinogens; Disease Models, Animal; Erythrocytes; Female; Lipid Peroxidation; Mammary Neoplasms, Experimental; Plant Extracts; Protoporphyrins; Rats; Rats, Sprague-Dawley; Semecarpus; Spectrometry, Fluorescence | 2015 |
Simultaneous determination of centchroman and tamoxifen along with their metabolites in rat plasma using LC-MS/MS.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Centchroman; Chromatography, Liquid; Female; Mammary Neoplasms, Experimental; Metabolomics; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tamoxifen; Tandem Mass Spectrometry; Tissue Distribution | 2015 |
Nordihydroguaiaretic acid ameliorates cisplatin induced nephrotoxicity and potentiates its anti-tumor activity in DMBA induced breast cancer in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antioxidants; Blood Urea Nitrogen; Catalase; Cisplatin; Creatinine; Female; Kidney; Kidney Diseases; Lipid Peroxidation; Mammary Neoplasms, Experimental; Masoprocol; Rats, Sprague-Dawley; Superoxide Dismutase; Tumor Burden | 2015 |
The effect of zinc and phytoestrogen supplementation on the changes in mineral content of the femur of rats with chemically induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Diet; Dietary Supplements; Factor Analysis, Statistical; Female; Femur; Iron; Liver; Mammary Neoplasms, Experimental; Minerals; Organ Size; Phytoestrogens; Rats, Sprague-Dawley; Spleen; Zinc | 2015 |
The Role of Dietary Extra Virgin Olive Oil and Corn Oil on the Alteration of Epigenetic Patterns in the Rat DMBA-Induced Breast Cancer Model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Corn Oil; Diet, High-Fat; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Olive Oil; Promoter Regions, Genetic; Protein Processing, Post-Translational; Rats, Sprague-Dawley; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-3; Tumor Suppressor Proteins | 2015 |
Cx26 knockout predisposes the mammary gland to primary mammary tumors in a DMBA-induced mouse model of breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Connexin 26; Connexins; Disease Models, Animal; Female; Fluorescent Antibody Technique; Humans; Integrases; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Knockout | 2015 |
Chemopreventive potential of fungal taxol against 7, 12-dimethylbenz[a]anthracene induced mammary gland carcinogenesis in Sprague Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; bcl-2-Associated X Protein; Breast; Carcinogenesis; Caspase 9; Female; Fungi; Kidney; Liver; Mammary Neoplasms, Experimental; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Tumor Suppressor Protein p53 | 2015 |
Suppressing NRIP1 inhibits growth of breast cancer cells in vitro and in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice, Knockout; Microscopy, Fluorescence; Nuclear Proteins; Nuclear Receptor Interacting Protein 1; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference | 2015 |
Pomegranate exerts chemoprevention of experimentally induced mammary tumorigenesis by suppression of cell proliferation and induction of apoptosis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Cell Proliferation; Female; Gene Expression Regulation; Lythraceae; Mammary Neoplasms, Experimental; Phytotherapy; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 2016 |
Luteolin suppresses development of medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced mammary tumors in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Estrogen Replacement Therapy; Female; Immunohistochemistry; Luteolin; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A | 2016 |
Inhibition of NF-κB, Bcl-2 and COX-2 Gene Expression by an Extract of Eruca sativa Seeds during Rat Mammary Gland Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Apoptosis; Brassicaceae; Carcinogens; Cell Proliferation; Cyclooxygenase 2; Female; Gene Expression Regulation, Neoplastic; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; NF-kappa B; Oxidative Stress; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seeds | 2015 |
Combination between Taxol-Encapsulated Liposomes and Eruca sativa Seed Extract Suppresses Mammary Tumors in Female Rats Induced by 7,12 Dimethylbenz(α)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Brassicaceae; Breast Neoplasms; Cell Proliferation; Cyclooxygenase 2; Female; Glutathione Transferase; Inflammation; Lipid Peroxidation; Liposomes; Mammary Neoplasms, Experimental; NF-kappa B; Paclitaxel; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Rats; Seeds; Superoxide Dismutase | 2016 |
Taurine Attenuates Dimethylbenz[a]anthracene-induced Breast Tumorigenesis in Rats: A Plasma Metabolomic Study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Female; Gas Chromatography-Mass Spectrometry; Mammary Neoplasms, Experimental; Metabolomics; Plasma; Rats; Rats, Sprague-Dawley; Taurine | 2016 |
In utero exposure of rats to high-fat diets perturbs gene expression profiles and cancer susceptibility of prepubertal mammary glands.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Diet, High-Fat; Female; Gene Expression Profiling; Genetic Predisposition to Disease; Mammary Neoplasms, Experimental; Pregnancy; Rats; Rats, Sprague-Dawley; Sexual Maturation | 2016 |
Chemometric analysis of the interactions among different parameters describing health conditions, breast cancer risk and fatty acids profile in serum of rats supplemented with conjugated linoleic acids.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Dose-Response Relationship, Drug; Drug Administration Schedule; Fatty Acids; Female; Least-Squares Analysis; Linoleic Acids, Conjugated; Mammary Neoplasms, Experimental; Rats; Risk Factors | 2016 |
Fish oil augments celecoxib mediated alteration in apoptotic pathway in the initiation phase of 7,12-dimethylbenz(α)anthracene-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; bcl-2-Associated X Protein; Carcinogenesis; Caspase 8; Celecoxib; Cell Separation; Cytochromes c; Epithelial Cells; Fas Ligand Protein; fas Receptor; Female; Fish Oils; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Membrane Potential, Mitochondrial; Rats, Wistar; Signal Transduction | 2016 |
Progesterone receptor antagonism inhibits progestogen-related carcinogenesis and suppresses tumor cell proliferation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antigens, CD34; Antineoplastic Agents, Hormonal; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Female; Hormone Antagonists; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Methylnitrosourea; Mice; Mifepristone; Neovascularization, Pathologic; Norpregnadienes; Progesterone; Progestins; Rats; Receptors, Estrogen; Receptors, Progesterone; Time Factors | 2016 |
Modulatory Effect of Taurine on 7,12-Dimethylbenz(a)Anthracene-Induced Alterations in Detoxification Enzyme System, Membrane Bound Enzymes, Glycoprotein Profile and Proliferative Cell Nuclear Antigen in Rat Breast Tissue.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Cytochromes; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glycoproteins; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Membrane Transport Proteins; Metabolic Detoxication, Phase I; Metabolic Detoxication, Phase II; Proliferating Cell Nuclear Antigen; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Taurine | 2016 |
Crateva adansonii DC, an African ethnomedicinal plant, exerts cytotoxicity in vitro and prevents experimental mammary tumorigenesis in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Africa; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Capparaceae; Chromatography, Liquid; DNA Damage; Dose-Response Relationship, Drug; Ethnobotany; Female; Human Umbilical Vein Endothelial Cells; Humans; Inhibitory Concentration 50; Lethal Dose 50; Mammary Neoplasms, Experimental; MCF-7 Cells; Medicine, African Traditional; Mice; Molecular Structure; NIH 3T3 Cells; Oxidative Stress; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Tamoxifen; Time Factors; Tumor Burden | 2016 |
Paternal selenium deficiency but not supplementation during preconception alters mammary gland development and 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in female rat offspring.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Dietary Supplements; Female; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Selenium | 2016 |
Development of Novel Polymer-Lipid Hybrid Nanoparticles of Tamoxifen: In Vitro and In Vivo Evaluation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Carriers; Drug Screening Assays, Antitumor; Female; Mammary Neoplasms, Experimental; Nanoparticles; Rats; Rats, Sprague-Dawley; Tamoxifen | 2016 |
Stage-Specific MicroRNAs and Their Role in the Anticancer Effects of Calorie Restriction in a Rat Model of ER-Positive Luminal Breast Cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Caloric Restriction; Disease Progression; Disease-Free Survival; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; MCF-7 Cells; MicroRNAs; Oligoribonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Tumor Burden | 2016 |
Daphnetin ameliorates 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis through Nrf-2-Keap1 and NF-κB pathways.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Biomarkers, Tumor; Carcinogenesis; Cytokines; Female; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Kelch-Like ECH-Associated Protein 1; Lipid Peroxidation; Mammary Neoplasms, Experimental; Neoplasm Proteins; NF-E2-Related Factor 2; NF-kappa B; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Umbelliferones | 2016 |
Induction of apoptosis and downregulation of ERα in DMBA-induced mammary gland tumors in Sprague-Dawley rats by synthetic 3,5-disubstituted isoxazole derivatives.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenols; Animals; Apoptosis; Down-Regulation; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Neoplasm Proteins; Rats; Rats, Sprague-Dawley | 2016 |
DMBA induced mouse mammary tumors display high incidence of activating Pik3caH1047 and loss of function Pten mutations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Class I Phosphatidylinositol 3-Kinases; DNA Mutational Analysis; Exome Sequencing; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice, Inbred C57BL; Mice, Inbred DBA; Mutation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; RANK Ligand; Sequence Analysis, RNA; Time Factors; Transcriptome | 2016 |
Carcinogen 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis is accelerated in Smad3 heterozygous mice compared to Smad3 wild type mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogenesis; Carcinogens; Female; Heterozygote; Male; Mammary Neoplasms, Experimental; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Smad3 Protein; Tumor Suppressor Proteins | 2016 |
Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenovirus E1A Proteins; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; DNA Methylation; Drug Resistance, Neoplasm; Ethinyl Estradiol; Female; Galectin 3; Gene Expression; Gene Silencing; Histocompatibility Antigens Class I; Humans; Hydralazine; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mammary Neoplasms, Experimental; Neoplasm Recurrence, Local; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tamoxifen; Trans-Activators; Valproic Acid | 2017 |
Ganoderma lucidum total triterpenes induce apoptosis in MCF-7 cells and attenuate DMBA induced mammary and skin carcinomas in experimental animals.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Female; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Rats; Rats, Wistar; Reishi; Triterpenes | 2017 |
Lifetime Genistein Intake Increases the Response of Mammary Tumors to Tamoxifen in Rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Autophagy; Cytokines; Diet; Endoplasmic Reticulum Chaperone BiP; Estrogen Receptor Modulators; Female; Gene Expression Regulation, Neoplastic; Genistein; Isoflavones; Mammary Neoplasms, Experimental; Phytoestrogens; Rats; Rats, Sprague-Dawley; Recurrence; Soy Foods; Tamoxifen; Unfolded Protein Response | 2017 |
Dietary lipids differentially modulate the initiation of experimental breast carcinogenesis through their influence on hepatic xenobiotic metabolism and DNA damage in the mammary gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Corn Oil; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Dietary Supplements; DNA Damage; Female; Inactivation, Metabolic; Lipids; Liver; Mammary Neoplasms, Experimental; NAD(P)H Dehydrogenase (Quinone); Olive Oil; Rats, Sprague-Dawley; Xenobiotics | 2017 |
Dietary lariciresinol attenuates mammary tumor growth and reduces blood vessel density in human MCF-7 breast cancer xenografts and carcinogen-induced mammary tumors in rats.
Topics: 4-Butyrolactone; 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Butylene Glycols; Carcinogens; Cell Proliferation; Dietary Supplements; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Furans; Gene Expression Regulation, Neoplastic; Humans; Lignans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Ovariectomy; Phytoestrogens; Rats; Receptors, Progesterone; Transplantation, Heterologous | 2008 |
Purple corn color suppresses Ras protein level and inhibits 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthocyanins; Anticarcinogenic Agents; Apoptosis; Carcinogens; Caspase 3; Down-Regulation; Female; Glucosides; Mammary Neoplasms, Experimental; Proto-Oncogene Mas; ras Proteins; Rats; Zea mays | 2008 |
Reduction by dietary matrix metalloproteinase inhibitor BAY 12-9566N of neoplastic development induced by diethylnitrosamine, N-nitrosodimethylamine, or 7,12-dimethylbenz(a)anthracene in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Antineoplastic Agents; Biphenyl Compounds; Carcinogens; Diethylnitrosamine; Dimethylnitrosamine; Drug Screening Assays, Antitumor; Female; Liver Neoplasms; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Matrix Metalloproteinase Inhibitors; Neoplasms; Organic Chemicals; Phenylbutyrates; Rats; Rats, Wistar; Sex Factors | 2008 |
Carcinogenic effects of intragastric 3-methylcholanthrene and 7,12-dimethylbenz[a]anthracene in Wistar and Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Fibroadenoma; Fibrocystic Breast Disease; Male; Mammary Neoplasms, Experimental; Methylcholanthrene; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stomach; Time Factors | 1966 |
Absence of Ras mutations in rat DMBA-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Codon; Female; Genes, ras; Mammary Neoplasms, Experimental; Mutation; Rats | 2009 |
Time-dependent acetylsalicylic acid effects on liver CYP1A and antioxidant enzymes in a rat model of 7,12-dimethylbenzanthracene (DMBA)-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Aspirin; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochromes; Female; Glucuronosyltransferase; Glutathione; Glutathione Transferase; Liver; Mammary Neoplasms, Experimental; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Sprague-Dawley | 2008 |
Chemopreventive effect of lycopene alone or with melatonin against the genesis of oxidative stress and mammary tumors induced by 7,12 dimethyl(a)benzanthracene in sprague dawely female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Carcinogens; Carotenoids; Female; Lycopene; Malondialdehyde; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Melatonin; Nitric Oxide; Oxidative Stress; Oxidoreductases; Rats; Rats, Sprague-Dawley | 2008 |
Genetic mapping of mammary tumor traits to rat chromosome 10 using a novel panel of consomic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromosome Mapping; Crosses, Genetic; Female; Genetic Predisposition to Disease; Male; Mammary Neoplasms, Experimental; Neoplasms, Multiple Primary; Phenotype; Quantitative Trait Loci; Rats; Rats, Inbred BN; Rats, Inbred Dahl | 2008 |
Characterization of breast cancer progression in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Progression; Female; Immunohistochemistry; Mammary Neoplasms, Experimental; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar | 2008 |
Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Composition; Body Weight; Carcinogens; Dietary Fats; Disease Models, Animal; Female; Longitudinal Studies; Male; Mammary Neoplasms, Experimental; Maternal Exposure; Metabolic Syndrome; Mice; Mice, Transgenic; Phenotype; Polychlorinated Dibenzodioxins; Pregnancy; Random Allocation; Receptors, Cytoplasmic and Nuclear | 2009 |
Breast cancer is associated with an increase in the activity and expression of cholinephosphotransferase in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animals; Biomarkers, Tumor; Blotting, Western; Carcinogens; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Female; Gene Expression Regulation, Enzymologic; Humans; Mammary Neoplasms, Experimental; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
[Different expression of liver-specific insulin-like growth factor I gene in breast cancer; expression with mice].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Gene Expression Regulation, Neoplastic; Insulin-Like Growth Factor I; Liver; Mammary Neoplasms, Experimental; Mice; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Random Allocation | 2008 |
Differential gene signatures in rat mammary tumors induced by DMBA and those induced by fractionated gamma radiation.
Topics: 5-Lipoxygenase-Activating Proteins; 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carrier Proteins; Cell Line, Tumor; DNA Damage; Dose Fractionation, Radiation; Female; Gamma Rays; Gene Expression Profiling; Histones; Humans; Mammary Neoplasms, Experimental; Membrane Proteins; Neoplasms, Radiation-Induced; Proliferating Cell Nuclear Antigen; Rats; RNA, Messenger; Tumor Suppressor Protein p53 | 2008 |
The inhibitory effect of bamboo extract on the development of 7,12-dimethylbenz[a]anthracene (DMBA)-induced breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antioxidants; Bambusa; Female; Flavonoids; Humans; Liver; Mammary Neoplasms, Experimental; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Sulfotransferases | 2008 |
Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogens; Choline; Choline Deficiency; Cluster Analysis; Female; Fetus; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Mammary Neoplasms, Experimental; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Survival Analysis; Time Factors | 2009 |
Combined supplementation of soy and garlic modulate biochemical parameters of 7,12-dimethylbenz[alpha]anthracene induced mammary cancer in female albino rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carcinogens; Dietary Supplements; Female; Garlic; Glutathione Transferase; Glycine max; L-Lactate Dehydrogenase; Mammary Neoplasms, Experimental; Rats; Superoxide Dismutase | 2007 |
Modifying effects of prepubertal exposure to potassium perchlorate and tetrabromobisphenol A on susceptibility to N-bis(2-hydroxypropyl)nitrosamine- and 7,12-dimethylbenz(a)anthracene-induced carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Carcinogenicity Tests; Cocarcinogenesis; Female; Male; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Nitrosamines; Perchlorates; Polybrominated Biphenyls; Potassium Compounds; Rats; Rats, Inbred F344; Thyroid Neoplasms | 2009 |
Prevention of chemically induced mammary tumorigenesis by daidzein in pre-pubertal rats: the role of peroxidative damage and antioxidative enzymes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Dose-Response Relationship, Drug; Enzymes; Female; Glutathione; Isoflavones; Mammary Neoplasms, Experimental; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sexual Maturation | 2009 |
Effects of 4-n-octylphenol on the induction of mammary tumors induced by 7,12-dimethylbenz[a]anthracene in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Female; Male; Mammary Neoplasms, Experimental; Phenols; Rats; Rats, Sprague-Dawley; Sex Characteristics; Testis | 2009 |
Rosiglitazone synergizes anticancer activity of cisplatin and reduces its nephrotoxicity in 7, 12-dimethyl benz{a}anthracene (DMBA) induced breast cancer rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Urea Nitrogen; Blotting, Western; Body Weight; Cisplatin; Creatinine; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Histones; Kidney; Kidney Diseases; Mammary Glands, Animal; Mammary Neoplasms, Experimental; p38 Mitogen-Activated Protein Kinases; Phosphorylation; PPAR gamma; Rats; Rats, Sprague-Dawley; Rosiglitazone; Serum Albumin; Thiazolidinediones; Tumor Burden; Tumor Necrosis Factor-alpha | 2009 |
Peritumoral TNFalpha administration influences tumour stroma structure and physiology independently of growth in DMBA-induced mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Collagen; Extracellular Fluid; Female; Interleukin-1beta; Mammary Neoplasms, Experimental; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2008 |
Chemopreventive efficacies of rosiglitazone, fenretinide and their combination against rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Estradiol; Female; Fenretinide; Hypoglycemic Agents; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Prolactin; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones | 2009 |
Intratumoral delivery of Paclitaxel in solid tumor from biodegradable hyaluronan nanoparticle formulations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Chemistry, Pharmaceutical; Female; Hyaluronic Acid; Mammary Neoplasms, Experimental; Nanoparticles; Paclitaxel; Rats; Rats, Sprague-Dawley; Solubility | 2009 |
Chemoprevention of rat mammary carcinogenesis by Azadirachta indica leaf fractions: modulation of hormone status, xenobiotic-metabolizing enzymes, oxidative stress, cell proliferation and apoptosis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Azadirachta; Body Weight; Carcinogens; Cell Proliferation; Chromatography, Thin Layer; Female; Hormones; Immunohistochemistry; Lipid Peroxidation; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Oxidative Stress; Plant Leaves; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Xenobiotics | 2009 |
Gene expression profiling during rat mammary carcinogenesis induced by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Blotting, Western; Carcinogens; Carcinoma, Intraductal, Noninfiltrating; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Microdissection; Neoplasm Invasiveness; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2009 |
The canonical NF-kappaB pathway is required for formation of luminal mammary neoplasias and is activated in the mammary progenitor population.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; CD24 Antigen; Humans; I-kappa B Kinase; Integrin alpha6; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplastic Stem Cells; NF-kappa B; Receptor, ErbB-2; Signal Transduction; Transcription Factor RelA | 2009 |
Potentiation of the antitumor effect of tamoxifen by combination with the antiprogestin onapristone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Gonanes; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Tamoxifen | 2009 |
Microalterations of inherently unstable genomic regions in rat mammary carcinomas as revealed by long oligonucleotide array-based comparative genomic hybridization.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Base Sequence; Carcinogens; DNA Primers; Mammary Neoplasms, Experimental; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Rats | 2009 |
Decreased levels of both Stat1 and Stat3 in T lymphocytes from mice bearing mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Blotting, Western; Carcinogens; Enzyme-Linked Immunosorbent Assay; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; STAT1 Transcription Factor; STAT3 Transcription Factor; T-Lymphocytes | 2009 |
Evaluation of molecular markers in a rat model of mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Biomarkers, Tumor; Blotting, Western; Carcinogens; Female; Humans; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Neoplasm Invasiveness; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2009 |
Anticancer activity of fungal taxol derived from Botryodiplodia theobromae Pat., an endophytic fungus, against 7, 12 dimethyl benz(a)anthracene (DMBA)-induced mammary gland carcinogenesis in Sprague Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Ascomycota; Carcinogens; Cyclooxygenase 2; Female; Immunohistochemistry; Lipid Peroxidation; Mammary Neoplasms, Experimental; Morinda; Paclitaxel; Rats; Rats, Sprague-Dawley | 2010 |
Obesity and the associated mediators leptin, estrogen and IGF-I enhance the cell proliferation and early tumorigenesis of breast cancer cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Analysis of Variance; Animals; Body Weight; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cell Proliferation; Dietary Fats; Disease Models, Animal; Estradiol; Female; Groin; Humans; Immunohistochemistry; Insulin-Like Growth Factor I; Leptin; Lymph Nodes; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Obesity; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors | 2009 |
Effects of beta-ionone on mammary carcinogenesis and antioxidant status in rats treated with DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Catalase; Diet; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; L-Lactate Dehydrogenase; Lipid Peroxidation; Mammary Neoplasms, Experimental; Norisoprenoids; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2010 |
Targeted production of proprotein convertase PC1 enhances mammary development and tumorigenesis in transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; DNA, Complementary; Female; Humans; Kaplan-Meier Estimate; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Oligonucleotide Array Sequence Analysis; Proprotein Convertase 1; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
Anti-breast cancer potential of SS1020, a novel antiestrogen lacking estrogenic and genotoxic actions.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; DNA Adducts; Endometrial Neoplasms; Estrogen Antagonists; Estrogen Receptor Modulators; Female; Humans; Mammary Neoplasms, Experimental; Mice; Rats; Tamoxifen; Uterus | 2010 |
Fish oil regulates cell proliferation, protect DNA damages and decrease HER-2/neu and c-Myc protein expression in rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Corn Oil; Dietary Supplements; DNA Breaks, Double-Stranded; DNA Breaks, Single-Stranded; DNA Damage; Docosahexaenoic Acids; Down-Regulation; Drug Combinations; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Female; Fish Oils; Immunohistochemistry; Ki-67 Antigen; Mammary Neoplasms, Experimental; Proto-Oncogene Proteins c-myc; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2 | 2010 |
Dynamic expression of a LEF-EGFP Wnt reporter in mouse development and cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Catenin; Carcinogens; Cells, Cultured; Embryo, Mammalian; Female; Fibroblasts; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Green Fluorescent Proteins; Immunoblotting; Lymphoid Enhancer-Binding Factor 1; Male; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Microscopy, Fluorescence; Response Elements; Tumor Cells, Cultured; Wnt Proteins | 2010 |
Role of ERalpha in the differential response of Stat5a loss in susceptibility to mammary preneoplasia and DMBA-induced carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinogens; Disease Models, Animal; DNA Primers; Estrogen Receptor alpha; Genetic Predisposition to Disease; Immunohistochemistry; Mammary Neoplasms, Experimental; Mice; Precancerous Conditions; STAT5 Transcription Factor | 2010 |
Protective effect of Thuja occidentalis against DMBA-induced breast cancer with reference to oxidative stress.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Chromatography, Thin Layer; Doxorubicin; Drug Screening Assays, Antitumor; Female; Glutathione; Longevity; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred ICR; Oxidative Stress; Plant Extracts; Thuja | 2010 |
Antiproliferative effect of peripheral benzodiazepine receptor antagonist PK11195 in rat mammary tumor cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Benzodiazepinones; Carrier Proteins; Cell Cycle; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Female; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Isoquinolines; Ki-67 Antigen; Mammary Neoplasms, Experimental; Neoplasm Invasiveness; Phenotype; Platelet Endothelial Cell Adhesion Molecule-1; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Time Factors; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2010 |
Prepubertal exposure to cow's milk reduces susceptibility to carcinogen-induced mammary tumorigenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Apoptosis; Body Weight; Carcinogens; Cell Proliferation; Cyclin D1; Disease Susceptibility; Estradiol; Estrogen Receptor alpha; Female; Gene Expression; Immunohistochemistry; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Milk; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Sexual Maturation; Time Factors | 2011 |
Therapeutic effect of centchroman alone and in combination with glycine soya on 7,12-dimethylbenz[alpha]anthracene-induced breast tumor in rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Proliferation; Centchroman; Estrogen Antagonists; Female; Glycine max; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Receptors, Estrogen | 2010 |
In vivo inhibition of the estrogen sulfatase enzyme and growth of DMBA-induced mammary tumors by melatonin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrone; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Melatonin; Ovariectomy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfatases; Time Factors; Tumor Burden; Uterus | 2010 |
Cancer collusion? Dietary fat may modify dioxin-induced mammary cancer risk.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Dietary Fats; Endocrine Disruptors; Female; Humans; Mammary Neoplasms, Experimental; Mice; Polychlorinated Dibenzodioxins; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors | 2010 |
Chemopreventive potential of genistein and daidzein in combination during 7,12-dimethylbenz[a]anthracene (DMBA) induced mammary carcinogenesis in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Genistein; Isoflavones; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 2010 |
Combinatorial effect of fish oil (Maxepa) and 1alpha,25-dihydroxyvitamin D(3) in the chemoprevention of DMBA-induced mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Bromodeoxyuridine; Calcitriol; Carcinogens; Cell Proliferation; DNA Primers; Female; Fish Oils; Mammary Neoplasms, Experimental; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2010 |
Mammary gland differentiation by early life exposure to enantiomers of the soy isoflavone metabolite equol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Body Weight; Carcinogens; Disease Models, Animal; Equol; Female; Genistein; Isoflavones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Organ Size; Phytoestrogens; Rats; Rats, Sprague-Dawley; Stereoisomerism; Time Factors | 2010 |
Synthetic progestins differentially promote or prevent 7,12-dimethylbenz(a)anthracene-induced mammary tumors in sprague-dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cytoprotection; Disease Progression; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Female; Mammary Neoplasms, Experimental; Neoplasm Staging; Placebos; Progesterone Congeners; Rats; Rats, Sprague-Dawley | 2010 |
Identification of novel carcinogen-mediated mammary tumor susceptibility loci in the rat using the chromosome substitution technique.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chromosome Mapping; Female; Genetic Predisposition to Disease; Mammary Neoplasms, Experimental; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Rats | 2010 |
Anti-breast cancer potential of SS5020, a novel benzopyran antiestrogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cinnamates; DNA Adducts; Estrogen Receptor Modulators; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Cells, Circulating; Rats; Rats, Sprague-Dawley; Tamoxifen; Umbelliferones | 2011 |
Evaluation of the role of oxidative stress in chemopreventive action of fish oil and celecoxib in the initiation phase of 7,12-dimethyl benz(α)anthracene-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Female; Fish Oils; Glutamate Dehydrogenase; Lipid Peroxidation; Lipids; Mammary Neoplasms, Experimental; Mitochondria; N-Acetylneuraminic Acid; Oxidative Stress; Pyrazoles; Rats; Rats, Wistar; Sulfonamides | 2011 |
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Epithelial Cells; Female; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Invasiveness; Precancerous Conditions; Progesterone; Progestins; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B | 2010 |
Influence of diet enriched with conjugated linoleic acids on their distribution in tissues of rats with DMBA induced tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Supplements; Fatty Acids; Female; Linoleic Acids, Conjugated; Lipid Metabolism; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 2010 |
Neonatal experiences differentially influence mammary gland morphology, estrogen receptor {α} protein levels, and carcinogenesis in BALB/c mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Blotting, Western; Carcinogens; Estrogen Receptor alpha; Female; Immunohistochemistry; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Maternal Deprivation; Mice; Mice, Inbred BALB C; Reverse Transcriptase Polymerase Chain Reaction; Stress, Psychological | 2010 |
Glycine soya diet synergistically enhances the suppressive effect of tamoxifen and inhibits tamoxifen-promoted hepatocarcinogenesis in 7,12-dimethylbenz[α]anthracene-induced rat mammary tumor model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Diet; Drug Synergism; Female; Glutathione S-Transferase pi; Glycine max; Liver Neoplasms; Mammary Neoplasms, Experimental; Organ Size; Rats; Rats, Sprague-Dawley; Tamoxifen | 2011 |
Effect of maternal and postweaning folic acid supplementation on mammary tumor risk in the offspring.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Body Weight; Carcinogens; Dietary Supplements; DNA Methylation; DNA Modification Methylases; Female; Folic Acid; Male; Mammary Neoplasms, Experimental; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Sprague-Dawley | 2011 |
Mcs5c: a mammary carcinoma susceptibility locus located in a gene desert that associates with tenascin C expression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Congenic; Blotting, Western; Carcinogens; Comparative Genomic Hybridization; Disease Susceptibility; Female; Genetic Predisposition to Disease; Mammary Neoplasms, Experimental; Phenotype; Quantitative Trait Loci; Rats; Rats, Inbred WF; Rats, Inbred WKY; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tenascin | 2011 |
Deficiency in trefoil factor 1 (TFF1) increases tumorigenicity of human breast cancer cells and mammary tumor development in TFF1-knockout mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Blotting, Western; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cell Proliferation; DNA; Female; Gene Knockdown Techniques; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Knockout; Mice, Nude; Molecular Sequence Data; Peptides; Transplantation, Heterologous; Trefoil Factor-1; Tumor Suppressor Proteins | 2011 |
Effect of dietary supplementation on the prognostic value of urinary and serum 8-isoprostaglandin F2α in chemically-induced mammary carcinogenesis in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Biomarkers, Tumor; Carcinogens; Copper; Dietary Supplements; Dinoprost; Female; Genistein; Mammary Neoplasms, Experimental; Prognosis; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Zinc | 2011 |
Diets high in corn oil or extra-virgin olive oil provided from weaning advance sexual maturation and differentially modify susceptibility to mammary carcinogenesis in female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Analysis of Variance; Animals; Body Weight; Breast; Caseins; Cell Transformation, Neoplastic; Corn Oil; Dietary Fats; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Kisspeptins; Mammary Neoplasms, Experimental; Molecular Sequence Data; Olive Oil; Ovary; Plant Oils; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sexual Maturation | 2011 |
Evaluation of carcinogenic potential of diuron in a rat mammary two-stage carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Apoptosis; Biomarkers; Carcinogenicity Tests; Carcinogens; Caspase 3; Cell Proliferation; Disease Models, Animal; Diuron; ERRalpha Estrogen-Related Receptor; Female; Herbicides; Mammary Neoplasms, Experimental; Organ Size; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Receptors, Estrogen | 2011 |
Cell mediated immune responses through TLR4 prevents DMBA-induced mammary carcinogenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Interferon-gamma; Interleukin-12; Interleukin-17; Interleukin-23; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Neovascularization, Pathologic; T-Lymphocytes, Regulatory; Toll-Like Receptor 4; Transforming Growth Factor beta | 2012 |
Effects of maternal exposure to cow's milk high or low in isoflavones on carcinogen-induced mammary tumorigenesis among rat offspring.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cattle; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Isoflavones; Mammary Neoplasms, Experimental; Maternal Exposure; Milk; Pregnancy; Pregnancy Complications, Neoplastic; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2011 |
Combined supplementation of vanadium and fish oil suppresses tumor growth, cell proliferation and induces apoptosis in DMBA-induced rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinoma; Cell Proliferation; Chemoprevention; Dietary Supplements; DNA Breaks; Drug Therapy, Combination; Female; Fish Oils; Histones; Mammary Neoplasms, Experimental; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53; Vanadium | 2011 |
Effects of 5,6-benzoflavone, indole-3-carbinol (I3C) and diindolylmethane (DIM) on chemically-induced mammary carcinogenesis: is DIM a substitute for I3C?
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Epithelial Cells; Female; Indoles; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Transcription, Genetic; Tumor Burden | 2011 |
Physical confirmation and mapping of overlapping rat mammary carcinoma susceptibility QTLs, Mcs2 and Mcs6.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Congenic; Carcinogens; Chromosome Mapping; Disease Susceptibility; Female; Insulin-Like Growth Factor I; Male; Mammary Neoplasms, Experimental; Molecular Sequence Annotation; Quantitative Trait Loci; Rats; Rats, Inbred WF; Rats, Inbred WKY; Suppressor of Cytokine Signaling Proteins | 2011 |
Bisphenol A increases mammary cancer risk in two distinct mouse models of breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzhydryl Compounds; Cell Line, Tumor; Disease Susceptibility; Estrogens, Non-Steroidal; Female; Humans; Mammary Neoplasms, Experimental; Mice; Phenols; Pregnancy; Prenatal Exposure Delayed Effects; Transplantation, Heterologous | 2011 |
Gene expression profile of terminal end buds in rat mammary glands exposed to diethylstilbestrol in neonatal period.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Carcinogens; Caseins; Diethylstilbestrol; Estrogens, Non-Steroidal; Female; Fluorescent Antibody Technique; Gene Expression; Gene Expression Profiling; Genitalia, Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Microarray Analysis; Microdissection; Milk Proteins; NF-kappa B; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2011 |
Antineoplastic effect of iodine and iodide in dimethylbenz[a]anthracene-induced mammary tumors: association between lactoperoxidase and estrogen-adduct production.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinogens; Caspase 3; DNA Adducts; DNA Damage; Estrogens; Female; Iodine; Lactoperoxidase; Mammary Neoplasms, Experimental; Potassium Iodide; PPAR gamma; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thyroid Gland | 2011 |
Role of 5-lipoxygenase in resveratrol mediated suppression of 7,12-dimethylbenz(α)anthracene-induced mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Cell Proliferation; Cyclin D1; DNA Breaks; Female; Gene Expression Regulation, Neoplastic; In Situ Nick-End Labeling; Leukotriene B4; Lipid Peroxidation; Lipoxygenase Inhibitors; Mammary Glands, Animal; Mammary Neoplasms, Experimental; NF-kappa B; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Transforming Growth Factor beta1 | 2011 |
Deletion of cyclooxygenase 2 in mouse mammary epithelial cells delays breast cancer onset through augmentation of type 1 immune responses in tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cells, Cultured; Contraceptives, Oral, Synthetic; Cyclooxygenase 2; Cytokines; Eicosanoids; Epithelial Cells; Female; Immunoenzyme Techniques; Inflammation Mediators; Macrophages; Macrophages, Peritoneal; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone; Mice; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Th1 Cells | 2011 |
The non-protein coding breast cancer susceptibility locus Mcs5a acts in a non-mammary cell-autonomous fashion through the immune system and modulates T-cell homeostasis and functions.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Breast Neoplasms; CD4-Positive T-Lymphocytes; CD8 Antigens; Cytokines; Epithelial Cells; Female; Genetic Loci; Genetic Predisposition to Disease; Homeostasis; L-Selectin; Mammary Neoplasms, Experimental; Methylnitrosourea; NK Cell Lectin-Like Receptor Subfamily B; Rats; Rats, Inbred WKY; Receptors, Antigen, T-Cell; T-Lymphocytes; Th1 Cells; Th2 Cells | 2011 |
Inhibitory effects of combination of lycopene and genistein on 7,12- dimethyl benz(a)anthracene-induced breast cancer in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Carotenoids; Caspase 3; Caspase 9; Disease Models, Animal; Drug Therapy, Combination; Female; Genistein; Lycopene; Mammary Neoplasms, Experimental; Plant Extracts; Rats; Rats, Wistar | 2011 |
Quantification of epithelial cell differentiation in mammary glands and carcinomas from DMBA- and MNU-exposed rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Biomarkers; Carcinoma; Cell Differentiation; Cell Division; Cell Membrane; Cell Proliferation; Epithelial Cells; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Models, Biological; Rats; Up-Regulation | 2011 |
The effect of childbirth on carcinogenesis of DMBA-induced breast cancer in female SD rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Nuclear; Carcinogens; Cell Transformation, Neoplastic; Female; Ki-67 Antigen; Mammary Neoplasms, Experimental; Minichromosome Maintenance Complex Component 2; Nuclear Proteins; Parity; Pregnancy; Proliferating Cell Nuclear Antigen; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Tumor Burden | 2011 |
Effects of morin on the pharmacokinetics of docetaxel in rats with 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, High Pressure Liquid; Docetaxel; Female; Flavonoids; Half-Life; Humans; Injections, Intravenous; Intestinal Mucosa; Liver; Mammary Neoplasms, Experimental; Mass Spectrometry; Rats; Taxoids | 2011 |
Prevention of rat breast cancer by genistin and selenium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Anticarcinogenic Agents; Antioxidants; Estrogens; Female; Isoflavones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Prolactin; Rats; Rats, Sprague-Dawley; Selenium | 2012 |
Hesperidin protects renal and hepatic tissues against free radical-mediated oxidative stress during DMBA-induced experimental breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Citric Acid Cycle; Female; Free Radicals; Hesperidin; Kidney; Lipid Peroxidation; Liver; Mammary Neoplasms, Experimental; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley | 2011 |
Effect of Cu supplementation on genomic instability in chemically-induced mammary carcinogenesis in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Copper; Dietary Supplements; Female; Genomic Instability; Mammary Neoplasms, Experimental; Microsatellite Repeats; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2011 |
Overexpression of 5-lipoxygenase and its relation with cell proliferation and angiogenesis in 7,12-dimethylbenz(α)anthracene-induced rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonate 5-Lipoxygenase; Cell Proliferation; Female; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 2; Microvessels; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A | 2013 |
Genistein and daidzein, in combination, protect cellular integrity during 7,12-dimethylbenz[a]anthracene (DMBA) induced mammary carcinogenesis in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Cell Membrane; Drug Therapy, Combination; Female; Genistein; Glycoconjugates; Isoflavones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Phytoestrogens; Rats; Rats, Sprague-Dawley | 2011 |
Androgen resistance in female mice increases susceptibility to DMBA-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androgens; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Epithelial Cells; Female; Genetic Predisposition to Disease; Gonadotropins, Pituitary; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Androgen; Testosterone | 2012 |
The chemopreventive effect of mifepristone on mammary tumorigenesis is associated with an anti-invasive and anti-inflammatory gene signature.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Carcinogens; Carcinoma; Chemoprevention; Drug Evaluation, Preclinical; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hormone Antagonists; Inflammation; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Microarray Analysis; Mifepristone; Neoplasm Invasiveness; Paired Box Transcription Factors; PAX8 Transcription Factor | 2012 |
Oxidative stress in the in vivo DMBA rat model of breast cancer: suppression by a voltage-gated sodium channel inhibitor (RS100642).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; Female; Glutathione Peroxidase; Malondialdehyde; Mammary Neoplasms, Experimental; Mexiletine; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Channel Blockers; Superoxide Dismutase | 2012 |
Mitigation of DMBA-induced mammary carcinoma in experimental rats by antiangiogenic property of Kalpaamruthaa.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Breast Neoplasms; Cyclooxygenase 2 Inhibitors; Female; Mammary Neoplasms, Experimental; Nuts; Peptide Hydrolases; Phyllanthus emblica; Phytotherapy; Plant Extracts; Polyphenols; Rats; Rats, Sprague-Dawley; Semecarpus; Vascular Endothelial Growth Factor A | 2011 |
Drug-targeted inhibition of peroxisome proliferator-activated receptor-gamma enhances the chemopreventive effect of anti-estrogen therapy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anilides; Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Carcinogens; Carcinoma; Chemoprevention; Drug Synergism; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Mice; Microarray Analysis; Molecular Targeted Therapy; PPAR gamma | 2012 |
Influence of hesperidin on renal cell surface glycoprotein content, nucleic acids, lysosomal enzymes and macromolecules against 7, 12-dimethylbenz [a] anthracene induced experimental breast carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers; Carcinogens; Female; Glycoproteins; Hesperidin; Kidney; Lipids; Liver; Lysosomes; Macromolecular Substances; Mammary Neoplasms, Experimental; Nucleic Acids; Rats; Rats, Sprague-Dawley | 2012 |
Hesperidin a citrus bioflavonoid modulates hepatic biotransformation enzymes and enhances intrinsic antioxidants in experimental breast cancer rats challenged with 7, 12-dimethylbenz (a) anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Biomarkers; Carcinogens; Cytochrome P-450 Enzyme System; Cytochromes b5; Female; Glutathione; Hesperidin; Mammary Neoplasms, Experimental; NADPH-Ferrihemoprotein Reductase; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2012 |
Schizophyllan inhibits the development of mammary and hepatic carcinomas induced by 7,12 dimethylbenz(α)anthracene and decreases cell proliferation: comparison with tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Cell Proliferation; Female; Immunohistochemistry; Liver Neoplasms, Experimental; Mammary Neoplasms, Experimental; Mice; Proliferating Cell Nuclear Antigen; Receptors, Estrogen; Schizophyllum; Sizofiran; Survival Analysis; Tamoxifen | 2012 |
Photodynamic therapy for the treatment of induced mammary tumor in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hematoporphyrin Derivative; Mammary Neoplasms, Experimental; Photochemotherapy; Photosensitizing Agents; Rats; Rats, Sprague-Dawley | 2013 |
Genetically determined inflammatory-response related cytokine and chemokine transcript profiles between mammary carcinoma resistant and susceptible rat strains.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Chemokines; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Inflammation; Mammary Neoplasms, Experimental; Rats; Receptors, Chemokine; RNA, Messenger | 2012 |
In vivo evaluation of doxorubicin-loaded (PEG)(3)-PLA nanopolymersomes (PolyDoxSome) using DMBA-induced mammary carcinoma rat model and comparison with marketed LipoDox™.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Disease Models, Animal; Doxorubicin; Drug Carriers; Female; Mammary Neoplasms, Experimental; Nanoparticles; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2012 |
Steroid receptor coactivators, HER-2 and HER-3 expression is stimulated by tamoxifen treatment in DMBA-induced breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Body Weight; Female; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Experimental; Nuclear Receptor Coactivators; Proto-Oncogene Protein c-ets-2; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Receptor, ErbB-3; RNA, Messenger; Tamoxifen; Tumor Burden | 2012 |
BAC CGH-array identified specific small-scale genomic imbalances in diploid DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Banding; Chromosomes, Artificial, Bacterial; Chromosomes, Mammalian; Comparative Genomic Hybridization; Diploidy; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred WKY | 2012 |
Up-regulation of CacyBP/SIP during rat breast cancer development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Catenin; Female; Intracellular Signaling Peptides and Proteins; Mammary Neoplasms, Experimental; Rats, Sprague-Dawley; Up-Regulation | 2014 |
D-Pinitol attenuates 7, 12 dimethylbenz [a] anthracene induced hazards through modulating protein bound carbohydrates, adenosine triphosphatases and lysosomal enzymes during experimental mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenosine Triphosphatases; Animals; Breast; Carcinogens, Environmental; Female; Inositol; Liver; Lysosomes; Mammary Neoplasms, Experimental; Membrane Glycoproteins; Rats; Rats, Sprague-Dawley | 2012 |
PPARγ antagonist GW9662 induces functional estrogen receptor in mouse mammary organ culture: potential translational significance.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anilides; Animals; Anticarcinogenic Agents; Drug Synergism; Estradiol; Estrogen Receptor alpha; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Oxazoles; PPAR gamma; Precancerous Conditions; Receptors, Progesterone; Tamoxifen; Tissue Culture Techniques; Transcriptional Activation; Tyrosine | 2013 |
Human breast adenocarcinoma cytotoxicity and modulation of 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma in Balb/c mice by Acacia catechu (L.f.) Wild heartwood.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acacia; Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Death; Female; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Inbred BALB C; Phytotherapy; Plant Extracts | 2013 |
Effects of morin on the pharmacokinetics of etoposide in 7,12-dimethylbenz[a]anthracene-induced mammary tumors in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Administration, Intravenous; Animals; Antineoplastic Agents, Phytogenic; ATP-Binding Cassette Transporters; Cytochrome P-450 CYP3A; Drug Screening Assays, Antitumor; Etoposide; Female; Flavonoids; Gene Expression; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2013 |
Pharmacokinetic drug interactions between ondansetron and tamoxifen in female Sprague-Dawley rats with DMBA-induced mammary tumor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antiemetics; Area Under Curve; Carcinogens; Drug Interactions; Female; Infusions, Intravenous; Mammary Neoplasms, Experimental; Ondansetron; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Tamoxifen | 2013 |
Inhibitory effects of 17beta-estradiol and 4-n-octylphenol on 7,12-dimethylbenz[a]anthracene-induced mammary tumor development in human c-Ha-ras proto-oncogene transgenic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Genetically Modified; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Estradiol; Female; Gene Transfer Techniques; Genes, ras; Genetic Predisposition to Disease; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Phenols; Proto-Oncogene Mas; Rats; Tumor Cells, Cultured | 2002 |
Histopathologic characterization of mammary neoplastic lesions induced with 7,12 dimethylbenz(alpha)anthracene in the rat: a comparative analysis with human breast tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Breast Neoplasms; Female; Humans; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 2002 |
Dietary soy modulation of biochemical parameters in DMBA-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diet; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Glycine max; Mammary Neoplasms, Experimental; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone | 2002 |
Suppression of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in rats by resveratrol: role of nuclear factor-kappaB, cyclooxygenase 2, and matrix metalloprotease 9.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Breast Neoplasms; Carcinogens; Cell Division; Cyclooxygenase 2; Female; Humans; Immunohistochemistry; Isoenzymes; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Membrane Proteins; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Pharmacological actions of a novel, potent, tissue-selective benzopyran estrogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzopyrans; Bone Density; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Molecular Structure; Organ Size; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Uterus | 2002 |
Growth hormone-deficient dwarf animals are resistant to dimethylbenzanthracine (DMBA)-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Dwarfism; Female; Growth Hormone; Heterozygote; Immunity, Innate; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Lew; Reference Values | 2002 |
Comparative genomic hybridization analysis of PhIP-induced mammary carcinomas in rats reveals a cytogenetic signature.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chromosome Aberrations; Chromosomes; DNA, Neoplasm; Female; Imidazoles; Mammary Neoplasms, Experimental; Nucleic Acid Hybridization; Rats | 2002 |
cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; DNA, Complementary; Female; Imidazoles; Lactation; Mammary Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Pregnancy; Pregnancy Complications; Rats | 2002 |
Role of the progesterone receptor (PR) in susceptibility of mouse mammary gland to 7,12-dimethylbenz[a]anthracene-induced hormone-independent preneoplastic lesions in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aldosterone; Animals; Breast; Disease Susceptibility; Female; Hydrocortisone; Immunoenzyme Techniques; Insulin; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasms, Hormone-Dependent; Organ Culture Techniques; Precancerous Conditions; Prolactin; Receptors, Progesterone | 2002 |
Chemopreventive effect of celecoxib and expression of cyclooxygenase-1 and cyclooxygenase-2 on chemically-induced rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Blotting, Western; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Immunohistochemistry; Isoenzymes; Mammary Neoplasms, Experimental; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides | 2002 |
Spontaneous mammary tumors in aging Noble rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age of Onset; Animals; Carcinoma; Diethylstilbestrol; Drug Implants; Estradiol; Female; Fibroadenoma; Genetic Predisposition to Disease; Incidence; Male; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Metastasis; Neoplasm Transplantation; Ovariectomy; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Rodent Diseases; Species Specificity; Testosterone | 2003 |
Novel murine mammary epithelial cell lines that form osteolytic bone metastases: effect of strain background on tumor homing.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Polyomavirus Transforming; Antineoplastic Agents, Hormonal; Bone Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Epithelial Cells; Female; Genes, ras; Heart Ventricles; Humans; Keratins; Liver Neoplasms, Experimental; Male; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Neoplastic Cells, Circulating; Osteolysis; Osteopontin; Retroviridae; Sialoglycoproteins; Transfection; Tumor Cells, Cultured | 2003 |
A rat cell line derived from DMBA-induced mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Antineoplastic Agents; Carcinogens; Female; Immunohistochemistry; Karyotyping; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Microscopy, Electron; Neoplasm Transplantation; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 2003 |
An expression study of hormone receptors in spontaneously developed, carcinogen-induced and hormone-induced mammary tumors in female Noble rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinogens; DNA Primers; Female; Hormones; Immunohistochemistry; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Polymerase Chain Reaction; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Receptors, Prolactin | 2003 |
An anti-tumor necrosis factor-alpha antibody inhibits the development of experimental skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Monoclonal; Carcinogens; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Immunity, Innate; Keratinocytes; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Staging; Papilloma; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 2003 |
A rat model of syngeneic bone marrow transplantation during breast cancer therapy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bone Marrow Transplantation; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred WF; Recurrence; Survival Rate; Time Factors; Transplantation, Isogeneic; Tumor Cells, Cultured | 2003 |
Timing of oral glutamine on DMBA-induced tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animal Nutritional Physiological Phenomena; Animals; Arteries; Female; Glutamine; Glutathione; Intestinal Mucosa; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Time Factors | 2003 |
Elucidation of molecular targets of mammary cancer chemoprevention in the rat by organoselenium compounds using cDNA microarray.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogens; Female; Gene Expression Regulation; Glutathione; Mammary Neoplasms, Experimental; Models, Biological; Oligonucleotide Array Sequence Analysis; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction | 2003 |
Physical evidence of Mcs5, a QTL controlling mammary carcinoma susceptibility, in congenic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Congenic; Female; Genetic Predisposition to Disease; Heterozygote; Mammary Neoplasms, Experimental; Quantitative Trait Loci; Rats; Rats, Inbred WKY | 2003 |
Dose response study of conjugated fatty acid derived from safflower oil on mammary and colon carcinogenesis pretreated with 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethylhydrazine (DMH) in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Colonic Neoplasms; Dimethylhydrazines; Dose-Response Relationship, Drug; Fatty Acids; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Safflower Oil | 2003 |
TNP-470 inhibits 7,12-dimethylbenz[a]anthracene-induced mammary tumor formation when administered before the formation of carcinoma in situ but is not additive with tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antibiotics, Antineoplastic; Carcinogens; Carcinoma in Situ; Carcinoma, Intraductal, Noninfiltrating; Cyclohexanes; Disease Models, Animal; Drug Interactions; Female; Mammary Neoplasms, Experimental; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tamoxifen | 2003 |
Reduced circulating insulin-like growth factor I levels delay the onset of chemically and genetically induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Polyomavirus Transforming; Carcinogens; Disease Models, Animal; Female; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Proto-Oncogene Proteins p21(ras); Receptor, IGF Type 1; Risk Factors; Tumor Suppressor Protein p53 | 2003 |
Exposure to flaxseed or its purified lignan during suckling inhibits chemically induced rat mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Suckling; Body Weight; Butylene Glycols; Carcinogens; Diet; Disease Models, Animal; Female; Flax; Glucosides; Lactation; Lignans; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Reproduction | 2003 |
Effects of GSM-900 microwaves on DMBA-induced mammary gland tumors in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cell Phone; Female; Mammary Neoplasms, Experimental; Microwaves; Neoplasm Staging; Neoplasms, Radiation-Induced; Rats; Rats, Sprague-Dawley; Survival Rate; Whole-Body Irradiation | 2003 |
Effect of thiouracil on the development of mammary tumours in rats induced with 9,10-dimethyl-1,2-benzanthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Breast Neoplasms; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Rats; Thiouracil | 1962 |
A virus resembling that of endemic pneumonia isolated from lymphosarcoma induced in Swiss mice by 9,10 dimethyl 1,2 benzanthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Avian Leukosis; Benz(a)Anthracenes; Breast Neoplasms; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice; Oncogenic Viruses; Pneumonia; Pneumonia, Viral | 1963 |
EFFECT OF 2-METHYL-1,2-BIS-(3-PYRIDYL)-1-PROPANONE (METYRAPONE) ON THE PRODUCTION OF MAMMARY TUMOURS INDUCED IN RATS BY ORAL FEEDING WITH DIMETHYLBENZANTHRACENE.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Carcinogens; Ketones; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Metyrapone; Mineralocorticoid Receptor Antagonists; Necrosis; Neoplasms, Experimental; Pharmacology; Rats; Research; Toxicology | 1963 |
THREE TYPES OF MAMMARY TUMOUR INDUCED IN RATS BY FEEDING WITH DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benz(a)Anthracenes; Castration; Female; Humans; Hypophysectomy; Lactation; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Neoplasms; Ovary; Pathology; Rats; Research | 1964 |
RELATIONSHIP OF ADRENOCORTICAL INSUFFICIENCY TO SPONTANEOUS REGRESSION IN MAMMARY TUMOURS INDUCED IN RATS BY ORAL ADMINISTRATION OF DIMETHYLBENZANTHRACENE.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Adrenal Insufficiency; Animals; Benz(a)Anthracenes; Cortisone; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Neoplasm Regression, Spontaneous; Pharmacology; Physiology; Rats; Research | 1964 |
EFFECT OF PREGNANCY AND LACTATION ON GROWTH OF MAMMARY TUMOURS INDUCED BY 7,12-DIMETHLBENZ(A) ANTHRACENE (DMBA).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Anthracenes; Benz(a)Anthracenes; Breast Feeding; Carcinogens; Female; Humans; Lactation; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Pregnancy; Pregnancy Complications; Pregnancy, Animal; Rats; Research | 1965 |
Effect of soybean, Vicia faba, and vitamin C on the carcinogenicity of DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Carcinoma; Dose-Response Relationship, Drug; Female; Glycine max; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats | 1994 |
p53 function is required for hormone-mediated protection of mouse mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Estradiol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Progesterone; Tumor Suppressor Protein p53 | 2003 |
Induced antitumor immunity against DMBA-4 metastatic mammary tumors in rats using laser immunotherapy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adoptive Transfer; Animals; Carcinogens; Female; Freeze Drying; Immunotherapy; Laser Therapy; Mammary Neoplasms, Experimental; Neoplasm Metastasis; Rats; Rats, Inbred WF | 2003 |
Therapeutic effect of Semecarpus anacardium Linn. nut milk extract on carbohydrate metabolizing and mitochondrial TCA cycle and respiratory chain enzymes in mammary carcinoma rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carbohydrate Metabolism; Citric Acid Cycle; Drug Screening Assays, Antitumor; Electron Transport; Enzymes; Female; Glycolysis; Mammary Neoplasms, Experimental; Mitochondria; Nuts; Plant Extracts; Rats; Semecarpus | 2003 |
Inhibition of rat mammary tumorigenesis by concord grape juice constituents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Anthocyanins; Beverages; Cell Division; Female; Fruit; Mammary Neoplasms, Experimental; Plant Extracts; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured; Vitis | 2003 |
NMU-induced mammary carcinogenesis in female rats is influenced by repeated psychoemotional stress.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stress, Psychological; Time Factors | 2003 |
Human soluble p66 and p51 tumor-associated antigens promote the suppression of rat mammary tumors in comparison to commercial human albumin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Neoplasm; Female; Humans; Mammary Neoplasms, Experimental; Molecular Weight; Rats; Serum Albumin | 2004 |
Prepubertal estradiol and genistein exposures up-regulate BRCA1 mRNA and reduce mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; BRCA1 Protein; Cell Division; Estradiol; Female; Genistein; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Sexual Maturation; Up-Regulation | 2004 |
Significant differences in the effects of magnetic field exposure on 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in two substrains of Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Disease Models, Animal; Electromagnetic Fields; Female; Mammary Neoplasms, Experimental; Neoplasms, Radiation-Induced; Ornithine Decarboxylase; Rats; Rats, Sprague-Dawley; Species Specificity | 2004 |
A delayed chemically induced tumorigenesis in Brca2 mutant mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; BRCA2 Protein; Carcinogens; Female; Genes, BRCA2; Genomic Library; Germ-Line Mutation; Mammary Neoplasms, Experimental; Mice; Mice, Knockout; Stem Cells | 2004 |
Terminal endbuds and acini as the respective major targets for chemical and sporadic carcinogenesis in the mammary glands of human c-Ha-ras protooncogene transgenic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Genetically Modified; Carcinogens; Cell Division; Cell Transformation, Neoplastic; DNA Primers; Female; Genes, ras; Humans; In Situ Hybridization, Fluorescence; Mammary Neoplasms, Experimental; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Rats; Reverse Transcriptase Polymerase Chain Reaction | 2004 |
PPARgamma influences susceptibility to DMBA-induced mammary, ovarian and skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Susceptibility; DNA Primers; Female; Heterozygote; Humans; Mammary Neoplasms, Experimental; Mice; Ovarian Neoplasms; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Neoplasms; Survival Rate; Transcription Factors; Zinc Fingers | 2004 |
Lack of significant effects of genistein on the progression of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in ovariectomized Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Disease Progression; Dose-Response Relationship, Drug; Estrogens; Female; Genistein; Incidence; Mammary Neoplasms, Experimental; Ovariectomy; Random Allocation; Rats; Rats, Sprague-Dawley | 2003 |
Downregulation of estrogen receptor alpha and beta expression in carcinogen-induced mammary gland tumors of rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Down-Regulation; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Immunohistochemistry; Mammary Neoplasms, Experimental; Methylnitrosourea; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley | 2004 |
Low-fat milk promotes the development of 7,12-dimethylbenz(A)anthracene (DMBA)-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Eating; Estradiol; Female; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Milk; Rats; Rats, Sprague-Dawley | 2004 |
Long-term exposure to elevated levels of circulating TIMP-1 but not mammary TIMP-1 suppresses growth of mammary carcinomas in transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Albumins; Animals; Antigens, Polyomavirus Transforming; Apoptosis; Female; Lung Neoplasms; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Terminal Repeat Sequences; Tissue Inhibitor of Metalloproteinase-1; Transgenes | 2004 |
Inhibition of VEGFR2 prevents DMBA-induced mammary tumor formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinoma in Situ; DNA Primers; Female; Humans; Hyperplasia; Mammary Neoplasms, Experimental; Neovascularization, Pathologic; Piperidines; Quinazolines; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor Receptor-2 | 2004 |
Identification of novel differentially expressed genes by the effect of a high-fat n-6 diet in experimental breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alpha-Globulins; Animals; bcl-X Protein; Blotting, Northern; Carcinogens; Carrier Proteins; Corn Oil; Dietary Fats; Fatty Acids, Omega-6; Female; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reproducibility of Results; RNA, Long Noncoding; RNA, Untranslated; Thioredoxins | 2004 |
Hyperbaric oxygen alone or combined with 5-FU attenuates growth of DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimetabolites, Antineoplastic; Cell Division; Drug Combinations; Female; Fluorouracil; Hyperbaric Oxygenation; Mammary Neoplasms, Experimental; Microcirculation; Oxygen; Rats; Rats, Sprague-Dawley | 2004 |
Overexpression of the colony-stimulating factor (CSF-1) and/or its receptor c-fms in mammary glands of transgenic mice results in hyperplasia and tumor formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Cycle; Cell Transformation, Neoplastic; Female; Humans; Hyperplasia; Macrophage Colony-Stimulating Factor; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Receptor, Macrophage Colony-Stimulating Factor | 2004 |
Inhibition of mammary gland tumors by short-term treatment of estradiol-3-benzoate associated with down-regulation of estrogen receptor ERalpha and ERbeta.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkylating Agents; Animals; Carcinogens; Cell Differentiation; Down-Regulation; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley | 2004 |
Expression of angiogenic factors is upregulated in DMBA-induced rat mammary pathologies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenic Proteins; Angiopoietin-1; Animals; Carcinogens; Carcinoma in Situ; Carcinoma, Ductal; Female; Fibroblast Growth Factor 2; Gene Expression Profiling; Gene Expression Regulation; Hyperplasia; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Osteonectin; Phosphoproteins; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Thrombospondin 1; Urokinase-Type Plasminogen Activator; Vascular Endothelial Growth Factor A | 2004 |
Suppression of cell proliferation, DNA protein cross-links, and induction of apoptosis by vanadium in chemical rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Proliferation; Cross-Linking Reagents; DNA; Electrophoresis, Agar Gel; Female; In Situ Nick-End Labeling; Liver; Mammary Neoplasms, Experimental; Precancerous Conditions; Proteins; Rats; Rats, Sprague-Dawley; Vanadium; Water | 2004 |
Induction of experimental mammary carcinogenesis in rats with 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Carcinogens; Carcinoma; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 2004 |
Chemoprevention by grape seed extract and genistein in carcinogen-induced mammary cancer in rats is diet dependent.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chemoprevention; Diet; Dietary Supplements; Female; Genistein; Isoflavones; Mammary Neoplasms, Experimental; Methylnitrosourea; Plant Extracts; Rats; Rats, Sprague-Dawley; Seeds; Vitis | 2004 |
Stroma is not a major target in DMBA-mediated tumorigenesis of mouse mammary preneoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Line, Transformed; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Precancerous Conditions; Stromal Cells; Time Factors | 2005 |
Effect of dietary glutamine on tumor glutathione levels and apoptosis-related proteins in DMBA-induced breast cancer of rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Apoptosis; bcl-2-Associated X Protein; Carcinogens; Caspase 3; Caspases; Dietary Proteins; Dietary Supplements; Female; Glutamine; Glutathione; Mammary Neoplasms, Experimental; Models, Animal; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 2004 |
Possible enhancing effects of atrazine on growth of 7,12-dimethylbenz(a) anthracene-induced mammary tumors in ovariectomized Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Atrazine; Dose-Response Relationship, Drug; Female; Herbicides; Immunohistochemistry; Mammary Neoplasms, Experimental; Ovariectomy; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley | 2005 |
Expression analysis of the mouse S100A7/psoriasin gene in skin inflammation and mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Amino Acid Sequence; Animals; Calcium-Binding Proteins; Croton Oil; Dermatitis; Humans; Immunohistochemistry; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Neoplasms; S100 Calcium Binding Protein A7; S100 Proteins | 2005 |
Rat soluble tumor-associated antigens inhibit chemically-induced mammary tumorigenesis in syngeneic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Carcinogens; Electrophoresis, Polyacrylamide Gel; Female; Humans; Immunotherapy, Active; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Rapid induction of mammary cancer by repeated subcutaneous injection of the trans-3,4-dihydrodiol of 7,12-dimethylbenz[a]anthracene in the female Sprague-Dawley rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Injections, Subcutaneous; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Sarcoma; Solubility; Time Factors | 2005 |
[Effect of tamoxifen plus octreotide on DMBA-induced mammary tumors in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Drug Synergism; Female; Mammary Neoplasms, Experimental; Octreotide; Random Allocation; Rats; Rats, Wistar; Tamoxifen | 2005 |
Increased expression of MDM2, cyclin D1, and p27Kip1 in carcinogen-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Cycle Proteins; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Nuclear Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Rats; Rats, Sprague-Dawley; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2005 |
Structural determinants of plant lignans for growth of mammary tumors and hormonal responses in vivo.
Topics: 4-Butyrolactone; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Furans; Lignans; Male; Mammary Neoplasms, Experimental; Molecular Structure; Organ Size; Phytotherapy; Plants; Prostate; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Uterus | 2005 |
Vanadium, a versatile biochemical effector in chemical rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Survival; Chromosome Aberrations; Copper; Disease Models, Animal; DNA Damage; Female; In Vitro Techniques; Iron; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Spectrometry, X-Ray Emission; Vanadium; Zinc | 2005 |
Purple grape juice inhibits 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary tumorigenesis and in vivo DMBA-DNA adduct formation.
Topics: 8-Hydroxy-2'-Deoxyguanosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Beverages; Carcinogens; Deoxyguanosine; DNA Adducts; Female; Glutathione Transferase; Liver; Mammary Neoplasms, Experimental; Plant Extracts; Rats; Rats, Sprague-Dawley; Vitis | 2006 |
Histone H1 modulates the antioxidant status in 9,10-dimethylbenz[a]anthracene-induced experimental breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antioxidants; Erythrocyte Membrane; Fatty Acids; Female; Histones; Mammary Neoplasms, Experimental; Oxidative Stress; Rats; Rats, Wistar | 2005 |
Opposing effects of prepubertal low- and high-fat n-3 polyunsaturated fatty acid diets on rat mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Diet; Diet, Fat-Restricted; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Sexual Maturation | 2005 |
Lack of prepubertal administration of ethinyl estradiol on susceptibility to multiple organ carcinogenesis in rats exposed to 7,12-dimethylbenz[a]anthracene and N-bis(2-hydroxypropyl)nitrosamine during adolescence.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Disease Susceptibility; Ethinyl Estradiol; Female; Male; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344 | 2005 |
CYP1 and AhR expression in 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma of rats prenatally exposed to 3,3',4,4',5-pentachlorobiphenyl.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Body Weight; Carcinogens, Environmental; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Female; Immunohistochemistry; Male; Mammary Neoplasms, Experimental; Organ Size; Polychlorinated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
Chemopreventive activities of Trigonella foenum graecum (Fenugreek) against breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animals; Cadherins; Carcinogens; Chemoprevention; Female; Immunoenzyme Techniques; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Microscopy, Electron; Microscopy, Polarization; Plant Extracts; Rats; Rats, Wistar; Receptors, Progesterone; Trigonella | 2005 |
Characterization of medroxyprogesterone and DMBA-induced multilineage mammary tumors by gene expression profiling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Mammary Neoplasms, Experimental; Medroxyprogesterone; Mice; RNA, Messenger | 2005 |
Hypermethylation patterns in the Fhit regulatory region are tissue specific.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acid Anhydride Hydrolases; Animals; Base Sequence; Carcinogens; DNA Methylation; DNA Primers; Female; Gene Expression Regulation; Genes, Regulator; Genes, Tumor Suppressor; Introns; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Proteins; Organ Specificity; Polymerase Chain Reaction; Rats | 2005 |
Exposure to light-at-night increases the growth of DMBA-induced mammary adenocarcinomas in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Body Weight; Circadian Rhythm; Darkness; Estradiol; Estrus; Female; Light; Mammary Neoplasms, Experimental; Melatonin; Rats; Rats, Sprague-Dawley; Survival Rate | 2006 |
Combined efficacy of tamoxifen and coenzyme Q10 on the status of lipid peroxidation and antioxidants in DMBA induced breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents, Hormonal; Antioxidants; Cell Proliferation; Coenzymes; Cytoprotection; Drug Combinations; Female; Lipid Peroxidation; Malondialdehyde; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Tamoxifen; Ubiquinone | 2005 |
Suppression of 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis by pre-initiation treatment of rats with beta-naphthoflavone coincides with decreased levels of the carcinogen-derived DNA adducts in the mammary gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; beta-Naphthoflavone; Carcinogens; Cytochrome P-450 Enzyme System; Disease Models, Animal; DNA Adducts; Enzyme Induction; Enzyme Inhibitors; Female; Glucuronosyltransferase; Glutathione Transferase; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 2005 |
Vitamin D receptor (VDR) ablation alters carcinogen-induced tumorigenesis in mammary gland, epidermis and lymphoid tissues.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Epidermis; Female; Lymphoid Tissue; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone; Mice; Mice, Knockout; Receptors, Calcitriol; Survival Analysis; Vitamin D | 2005 |
Mice lacking the amplified in breast cancer 1/steroid receptor coactivator-3 are resistant to chemical carcinogen-induced mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Growth Processes; Cyclin D1; Female; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nuclear Receptor Coactivator 3; Pituitary Gland; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Transcription Factors | 2005 |
Ospemifene inhibits the growth of dimethylbenzanthracene-induced mammary tumors in Sencar mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinoma; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred SENCAR; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen | 2005 |
Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Female; Genes, p53; Genetic Predisposition to Disease; Humans; Inbreeding; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Transgenic; Milk Proteins; Point Mutation; Pregnancy; Recombinases | 2005 |
Obesity promotes 7,12-dimethylbenz(a)anthracene-induced mammary tumor development in female zucker rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Obesity; Overweight; Rats; Rats, Sprague-Dawley; Rats, Zucker; Thinness | 2005 |
Melatonin increases the survival time of animals with untreated mammary tumours: neuroendocrine stabilization.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Catecholamines; Epinephrine; Female; Killer Cells, Natural; Mammary Neoplasms, Experimental; Melatonin; Prolactin; Rats; Rats, Sprague-Dawley; Survival Rate; Tumor Burden | 2005 |
Hint1 is a haplo-insufficient tumor suppressor in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; DNA Primers; Female; Genes, Tumor Suppressor; Haplotypes; Mammary Neoplasms, Experimental; Mice; Nerve Tissue Proteins; Ovarian Neoplasms | 2006 |
[The effect of selective cyclooxygenase-2 inhibitor nimesulide on breast cancer induced by dimethylbenzoic acid in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cyclooxygenase 2 Inhibitors; Dinoprostone; Female; Mammary Neoplasms, Experimental; Random Allocation; Rats; Rats, Wistar; Sulfonamides | 2005 |
Substituted phenanthrenes with basic amino side chains: a new series of anti-breast cancer agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acids; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Inhibitory Concentration 50; Mammary Neoplasms, Experimental; Models, Chemical; Phenanthrenes; Rats; Tamoxifen; Time Factors | 2006 |
New nutrition, proteomics, and how both can enhance studies in cancer prevention and therapy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Brain; Carcinogens; Electrophoresis, Gel, Two-Dimensional; Female; Flavonoids; Mammary Neoplasms, Experimental; Neoplasms; Nutritional Physiological Phenomena; Phenols; Plant Extracts; Polyphenols; Proanthocyanidins; Proteomics; Rats; Rats, Sprague-Dawley; Seeds; Vitis | 2005 |
Oncogenic signaling pathways activated in DMBA-induced mouse mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; beta Catenin; Carcinogens; Casein Kinase II; DNA; Female; Gene Expression Regulation, Neoplastic; Genes, bcl-1; Genes, myc; Mammary Neoplasms, Experimental; Mice; NF-kappa B; NIMA-Interacting Peptidylprolyl Isomerase; Oncogenes; Peptidylprolyl Isomerase; Receptors, Aryl Hydrocarbon; Retinoblastoma Protein; RNA, Messenger; Signal Transduction; Wnt Proteins | 2005 |
Preventive effect of the soluble tumor-associated antigens on DMBA induced tumorigenesis in C3H/He mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Cancer Vaccines; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Ovarian Neoplasms; Stomach Neoplasms; Time Factors; Uterine Neoplasms | 2005 |
Chemopreventive efficacy and anti-lipid peroxidative potential of Jasminum grandiflorum Linn. on 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Jasminum; Lipid Peroxidation; Mammary Neoplasms, Experimental; Plant Extracts; Rats; Rats, Wistar | 2005 |
Therapeutic effect of paclitaxel and propolis on lipid peroxidation and antioxidant system in 7,12 dimethyl benz(a)anthracene-induced breast cancer in female Sprague Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Ascorbic Acid; Body Weight; Carcinogens; Catalase; Female; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Mammary Neoplasms, Experimental; Paclitaxel; Propolis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vitamin E | 2006 |
Influence of estradiol on mammary tumor collagen solubility in DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Collagen; Estradiol; Female; Lactic Acid; Mammary Neoplasms, Experimental; Progesterone; Prolactin; Rats; Rats, Wistar; Solubility | 2006 |
Power frequency magnetic fields increase cell proliferation in the mammary gland of female Fischer 344 rats but not various other rat strains or substrains.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Proliferation; Female; Magnetics; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred F344; Rats, Inbred Strains | 2005 |
Effects of 900 MHz GSM wireless communication signals on DMBA-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Burden; Carcinogens; Cell Phone; Dose-Response Relationship, Radiation; Environmental Exposure; Female; Mammary Neoplasms, Experimental; Microwaves; Neoplasms, Radiation-Induced; Radiation Dosage; Rats; Rats, Sprague-Dawley; Whole-Body Irradiation | 2006 |
Override of the osteoclast defect in osteopontin-deficient mice by metastatic tumor growth in the bone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bone Neoplasms; Epithelial Cells; Female; Integrin-Binding Sialoprotein; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Mice, Knockout; Osteoclasts; Osteopontin; Osteoporosis; Parathyroid Hormone-Related Protein; Reverse Transcriptase Polymerase Chain Reaction; Sialoglycoproteins; Transfection; Tumor Cells, Cultured | 2006 |
Anticancer effect of Kalpaamruthaa on mammary carcinoma in rats with reference to glycoprotein components, lysosomal and marker enzymes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Biomarkers; Body Weight; Carcinogens; Dose-Response Relationship, Drug; Female; Glycoproteins; Kidney; Liver; Lysosomes; Mammary Neoplasms, Experimental; Organ Size; Plant Extracts; Rats; Rats, Sprague-Dawley | 2006 |
7,12-dimethylbenz(a)anthracene treatment of a c-rel mouse mammary tumor cell line induces epithelial to mesenchymal transition via activation of nuclear factor-kappaB.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cadherins; Carcinoma, Adenosquamous; Cell Adhesion; Cell Growth Processes; Cell Line, Tumor; Cell Transformation, Neoplastic; Epithelial Cells; Genes, rel; I-kappa B Proteins; Mammary Neoplasms, Experimental; Mesoderm; Mice; Mice, Transgenic; NF-kappa B; NF-KappaB Inhibitor alpha; Proto-Oncogene Proteins c-rel | 2006 |
The activity of matrix metalloproteinases (MMPS) and tissue inhibitors of metalloproteinases (TIMPs) in mammary tumors of dogs and rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Breast Neoplasms; Carcinoma; Dog Diseases; Dogs; Electrophoresis, Polyacrylamide Gel; Female; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinases | 2006 |
The aspirin metabolite, salicylate, inhibits 7,12-dimethylbenz[a]anthracene-DNA adduct formation in breast cancer cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP1A1; DNA Adducts; Female; Humans; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Salicylates | 2006 |
Effects of radical oxygen species and NO: formation of intracellular hypoxia and activation of matrix metalloproteinases in tumor tissues.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Hepatocellular; Cell Hypoxia; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Enzyme Activation; Female; Humans; Liver Neoplasms; Mammary Neoplasms, Experimental; Matrix Metalloproteinases; Nitric Oxide; Rats; Reactive Oxygen Species; Stomach Neoplasms | 2006 |
Dietary effects of soy isoflavones daidzein and genistein on 7,12-dimethylbenz[a]anthracene-induced mammary mutagenesis and carcinogenesis in ovariectomized Big Blue transgenic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Genetically Modified; Apoptosis; Body Weight; Diet; Female; Genistein; Hypoxanthine Phosphoribosyltransferase; Isoflavones; Lac Operon; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mutation; Organ Size; Ovariectomy; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred BB | 2006 |
Therapeutic effect of propolis and paclitaxel on hepatic phase I and II enzymes and marker enzymes in dimethylbenz(a)anthracene-induced breast cancer in female rats.
Topics: 5'-Nucleotidase; 9,10-Dimethyl-1,2-benzanthracene; Acid Phosphatase; Alkaline Phosphatase; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytochrome P-450 Enzyme System; Cytochromes b5; Female; Liver; Mammary Neoplasms, Experimental; NADPH-Ferrihemoprotein Reductase; Paclitaxel; Propolis; Rats; Rats, Sprague-Dawley; Transferases | 2006 |
Natural and synthetic progestins accelerate 7,12-dimethylbenz[a]anthracene-initiated mammary tumors and increase angiogenesis in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Implants; Immunohistochemistry; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mifepristone; Neovascularization, Pathologic; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Time Factors; Vascular Endothelial Growth Factors | 2006 |
Effect of Semecarpus anacardium Linn. nut milk extract on glutathione and its associated enzymes in experimentally induced mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; gamma-Glutamyltransferase; Glucosephosphate Dehydrogenase; Glutamate-Cysteine Ligase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Kidney; Liver; Mammary Neoplasms, Experimental; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Seeds; Semecarpus | 2006 |
[Effects of mobile-phone microwave on dimethylbenz (a) anthracene induced mammary carcinoma development in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Phone; Female; Mammary Neoplasms, Experimental; Microwaves; Radiation Dosage; Rats; Rats, Sprague-Dawley | 2006 |
Characterisation of two rat mammary tumour models for breast cancer research by gene expression profiling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Disease Models, Animal; Female; Gene Expression Profiling; Mammary Neoplasms, Experimental; Matrix Metalloproteinases; Neoplasms, Hormone-Dependent; Osteopontin; Rats; Rats, Inbred F344; Rats, Sprague-Dawley | 2006 |
Characterization of a preclinical model of simultaneous breast and ovarian cancer progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Alkylating Agents; Animals; Carcinogens; Carcinoma, Intraductal, Noninfiltrating; Cell Proliferation; Cells, Cultured; Cocarcinogenesis; Cyclooxygenase 2; Disease Models, Animal; Disease Progression; Epithelium; Estrogen Receptor alpha; Estrogens; Female; Hyperplasia; Immunoenzyme Techniques; Ki-67 Antigen; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovarian Neoplasms; Precancerous Conditions; Rats; Rats, Inbred F344 | 2007 |
Therapeutic efficacy of Kalpaamruthaa on reactive oxygen/nitrogen species levels and antioxidative system in mammary carcinoma bearing rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Carcinogens; Drug Evaluation, Preclinical; Female; Lipid Peroxidation; Mammary Neoplasms, Experimental; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2007 |
Modulation of p53 and c-myc in DMBA-induced mammary tumors by oral glutamine.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Carcinogens; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Glutamine; Glutathione; Mammary Neoplasms, Experimental; Proto-Oncogene Proteins c-myc; Random Allocation; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53 | 2006 |
Differentiation of spontaneous and induced mammary adenocarcinomas of the rat by gene expression profiling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Female; Gene Expression Profiling; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley | 2006 |
Maternal dietary exposure to fiber during pregnancy and mammary tumorigenesis among rat offspring.
Topics: 8-Hydroxy-2'-Deoxyguanosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Avena; Biomarkers, Tumor; Cellulose; Deoxyguanosine; Dietary Fiber; DNA Damage; Female; Flax; Genes, BRCA1; Mammary Neoplasms, Experimental; Maternal Exposure; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Triticum; Tumor Suppressor Protein p53 | 2006 |
The biochemical changes associated with phytic Acid on induced breast proliferative lesions in rats: preliminary findings.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Caspase 3; Cell Growth Processes; Female; Mammary Neoplasms, Experimental; N-Acetylneuraminic Acid; Nitric Oxide; Oxidative Stress; Phytic Acid; Rats; Rats, Sprague-Dawley | 2006 |
Lack of enhancement of susceptibility to mammary and thyroid carcinogenesis in rats exposed to DMBA and DHPN following prepubertal iodine deficiency.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Carcinogens; Disease Susceptibility; Female; Iodine; Male; Mammary Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344; Thyroid Neoplasms | 2006 |
High-dose, short-term, anti-inflammatory treatment with dexamethasone reduces growth and augments the effects of 5-fluorouracil on dimethyl-alpha-benzanthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Carcinogens; Dexamethasone; Drug Administration Schedule; Drug Synergism; Extracellular Fluid; Female; Fluorouracil; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Neovascularization, Pathologic; Pressure; Rats; Rats, Sprague-Dawley | 2006 |
Tumor-protective and tumor-promoting actions of dietary whey proteins in an N-methyl-N-nitrosourea model of rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Caseins; Cell Differentiation; Disease Models, Animal; Female; Genetic Predisposition to Disease; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Milk Proteins; Pregnancy; Prenatal Exposure Delayed Effects; Proliferating Cell Nuclear Antigen; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Whey Proteins | 2006 |
Suppression of cell proliferation, induction of apoptosis and cell cycle arrest: chemopreventive activity of vanadium in vivo and in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; bcl-2-Associated X Protein; Carcinogens; Cell Cycle; Cell Proliferation; Female; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; In Situ Nick-End Labeling; Mammary Neoplasms, Experimental; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vanadium Compounds | 2007 |
Anti-tumor promoting potential of luteolin against 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Anticarcinogenic Agents; Antioxidants; Body Weight; Catalase; Female; Glutathione Peroxidase; Lipid Peroxides; Luteolin; Mammary Neoplasms, Experimental; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors; Treatment Outcome | 2006 |
[Chemopreventive effect of tamoxifen combined with celecoxib on DMBA-induced breast cancer in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Drug Administration Routes; Drug Synergism; Female; Mammary Neoplasms, Experimental; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Tamoxifen | 2006 |
[Chemopreventive effect of celecoxib against DMBA-induced breast cancer and its mechanism].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Down-Regulation; Female; Immunohistochemistry; Mammary Neoplasms, Experimental; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Tamoxifen; Treatment Outcome; Vascular Endothelial Growth Factor A | 2006 |
Dietary effects of soy isoflavones daidzein and genistein on 7,12-dimethylbenz[a]anthracene-induced mammary mutagenesis and carcinogenesis in ovariectomized Big Blue transgenic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Genetically Modified; Female; Genistein; Glycine max; Isoflavones; Mammary Neoplasms, Experimental; Mutagenesis; Ovariectomy; Phytoestrogens; Rats | 2006 |
Exercise-induced stress enhances mammary tumor growth in rats: beneficial effect of the hormone melatonin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Epinephrine; Female; Mammary Neoplasms, Experimental; Melatonin; Physical Conditioning, Animal; Prolactin; Rats; Rats, Sprague-Dawley; Stress, Physiological; Survival Rate; Tumor Burden | 2007 |
Bin1 ablation in mammary gland delays tissue remodeling and drives cancer progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptor Proteins, Signal Transducing; Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Disease Progression; Female; Gene Deletion; Genes, ras; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Molecular Sequence Data; Nerve Tissue Proteins; Pregnancy; Tumor Suppressor Proteins | 2007 |
Isolation of two regions on rat chromosomes 5 and 18 affecting mammary cancer susceptibility.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Congenic; Carcinogens; Chromosome Mapping; Chromosomes; Crosses, Genetic; Female; Genetic Predisposition to Disease; Genotype; Mammary Neoplasms, Experimental; Quantitative Trait Loci; Quantitative Trait, Heritable; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley | 2007 |
Hyperoxia retards growth and induces apoptosis and loss of glands and blood vessels in DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Hyperbaric Oxygenation; Mammary Neoplasms, Experimental; Neovascularization, Pathologic; Oxygen; Rats; Rats, Sprague-Dawley | 2007 |
Obesity increases the incidence of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in an ovariectomized Zucker rat model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Female; Liver; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Obesity; Organ Size; Ovariectomy; Rats; Rats, Zucker; Time Factors | 2007 |
Hypoxia and its downstream targets in DMBA induced mammary carcinoma: protective role of Semecarpus anacardium nut extract.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carbonic Anhydrases; Carcinogens; Carcinoma; Endothelial Cells; Female; Glucose Transporter Type 1; Glycolysis; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Mammary Neoplasms, Experimental; Neovascularization, Pathologic; Nitric Oxide Synthase Type II; Nuts; Plant Extracts; Rats; Rats, Sprague-Dawley; Semecarpus; Tumor Burden; Vascular Endothelial Growth Factor A | 2007 |
Tumor-specific antivascular effect of TZT-1027 (Soblidotin) elucidated by magnetic resonance imaging and confocal laser scanning microscopy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Breast Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Imaging; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Microscopy, Confocal; Oligopeptides; Rats; Rats, Nude; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2007 |
Effect of Semecarpus anacardium nut extract on ECM and proteases in mammary carcinoma rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Extracellular Matrix; Female; Glycoside Hydrolases; Mammary Neoplasms, Experimental; Matrix Metalloproteinases, Secreted; Neoplasm Invasiveness; Nuts; Peptide Hydrolases; Plant Extracts; Rats; Rats, Sprague-Dawley; Semecarpus; Tissue Inhibitor of Metalloproteinases | 2007 |
Alteration of DMBA-induced oxidative stress by additive action of a modified indigenous preparation--Kalpaamruthaa.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Ascorbic Acid; Drug Synergism; Female; Glutathione; Liver; Mammary Neoplasms, Experimental; Medicine, Ayurvedic; Mitochondria, Liver; Oxidative Stress; Phytotherapy; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley; Vitamin E | 2007 |
Chemoprevention of rat mammary carcinogenesis by black tea polyphenols: modulation of xenobiotic-metabolizing enzymes, oxidative stress, cell proliferation, apoptosis, and angiogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Catalase; Cell Proliferation; Cytochrome P-450 Enzyme System; Female; gamma-Glutamyltransferase; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Immunohistochemistry; Lipid Peroxidation; Mammary Neoplasms, Experimental; Neovascularization, Pathologic; Oxidative Stress; Phenols; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tea; Xenobiotics | 2007 |
Sonodynamic therapy on chemically induced mammary tumor: pharmacokinetics, tissue distribution and sonodynamically induced antitumor effect of gallium-porphyrin complex ATX-70.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Area Under Curve; Combined Modality Therapy; Drug Screening Assays, Antitumor; Female; Mammary Neoplasms, Experimental; Photosensitizing Agents; Porphyrins; Rats; Rats, Sprague-Dawley; Time Factors; Tissue Distribution; Ultrasonic Therapy | 2007 |
Ineffectiveness of American ginseng in the prevention of dimethylbenzanthracene-induced mammary tumors in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred SENCAR; Panax; Phytotherapy; Plant Preparations; Plant Roots; Selective Estrogen Receptor Modulators; Tamoxifen; Time Factors | 2006 |
Effects of BRCA1 transgene expression on murine mammary gland development and mutagen-induced mammary neoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; BRCA1 Protein; Carcinogens; Female; Gene Expression; Gene Transfer Techniques; Genes, BRCA1; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred Strains; Mice, Transgenic; Pregnancy | 2007 |
Protective effect of Operculina turpethum against 7,12-dimethyl benz(a)anthracene induced oxidative stress with reference to breast cancer in experimental rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Convolvulaceae; Female; Mammary Neoplasms, Experimental; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley | 2007 |
Effect of milk on the 7,12-dimethylbenz[a]-anthracene-induced mammary tumor model in rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Cattle; Estradiol; Estrone; Female; Hormones; Mammary Neoplasms, Experimental; Milk; Organ Size; Progesterone; Rats; Rats, Sprague-Dawley | 2007 |
Chemopreventive effect of selenium-enriched Japanese radish sprout against breast cancer induced by 7,12-dimethylbenz[a]anthracene in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Brassica rapa; Carcinogens; Chemoprevention; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Selenium | 2007 |
Anti-progestins suppress the growth of established tumors induced by 7,12-dimethylbenz(a)anthracene: comparison between RU486 and a new 21-substituted-19-nor-progestin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Proliferation; Disease Progression; Female; Hormone Antagonists; Mammary Neoplasms, Experimental; Mifepristone; Norpregnadienes; Progesterone Congeners; Progestins; Rats; Rats, Sprague-Dawley | 2007 |
[Diethylstilbestrol intervention in carcinogenesis of breast cancer in wistar rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Nuclear; Carcinogens; Cell Proliferation; Diethylstilbestrol; Dose-Response Relationship, Drug; Epithelial Cells; Female; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats; Rats, Wistar; Receptor, ErbB-2 | 2007 |
Lack of a significant effect of arctiin on development of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in ovariectomized Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Disease Progression; Dose-Response Relationship, Drug; Female; Furans; Glucosides; Incidence; Mammary Neoplasms, Experimental; Ovariectomy; Random Allocation; Rats; Rats, Sprague-Dawley | 2007 |
(1)H nuclear magnetic resonance metabolomic analysis of mammary tumors from lean and obese Zucker rats exposed to 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biotransformation; Female; Least-Squares Analysis; Mammary Neoplasms, Experimental; Nuclear Magnetic Resonance, Biomolecular; Obesity; Protons; Rats; Rats, Zucker; Solubility; Thinness; Tissue Extracts | 2007 |
Pretreatment with phytoestrogen-rich plant decreases breast tumor incidence and exhibits lower profile of mammary ERalpha and ERbeta.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Mammary Neoplasms, Experimental; Phytoestrogens; Phytotherapy; Plant Tubers; Pueraria; Rats; Rats, Sprague-Dawley | 2007 |
Exposure of Fischer 344 rats to a weak power frequency magnetic field facilitates mammary tumorigenesis in the DMBA model of breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Disease Models, Animal; Female; Magnetics; Mammary Neoplasms, Experimental; Rats; Rats, Inbred F344 | 2008 |
Control of peripheral benzodiazepine receptor-mediated breast cancer in rats by soy protein.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzodiazepinones; Carcinogens; Female; Ligands; Mammary Neoplasms, Experimental; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Soybean Proteins; Tritium | 2008 |
Consumption of commercial whole and non-fat milk increases the incidence of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Dietary Fats; Female; Mammary Neoplasms, Experimental; Milk; Rats; Rats, Sprague-Dawley | 2007 |
Charles River Sprague Dawley rats lack early age-dependent susceptibility to DMBA-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Age Factors; Animals; Carcinogenicity Tests; Carcinoma; Disease Models, Animal; Disease Susceptibility; Female; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Pituitary Gland; Rats; Rats, Sprague-Dawley | 2007 |
Effects of neonatally administered diethylstilbestrol on induction of mammary carcinomas induced by 7, 12-dimethylbenz(a)anthracene in female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Corpus Luteum; Diethylstilbestrol; Estrus; Female; Ki-67 Antigen; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 2007 |
Study on potential effects of "902-MHz GSM-type Wireless Communication Signals" on DMBA-induced mammary tumours in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Organ Size; Radio Waves; Rats; Rats, Sprague-Dawley; Tumor Burden | 2008 |
[Correlation of insulin-like growth factor-1 (IGF-1) to angiogenesis of breast cancer in IGF-1-deficient mice].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Female; Ginsenosides; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Mice; Microvessels; Neovascularization, Pathologic; Random Allocation; Vascular Endothelial Growth Factor A | 2007 |
Gpx2 is an overexpressed gene in rat breast cancers induced by three different chemical carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Animals; Animals, Genetically Modified; Blotting, Western; Breast; Breast Neoplasms; Carcinogens; Cells, Cultured; Female; Gene Silencing; Genes, ras; Glutathione Peroxidase; Humans; Imidazoles; Mammary Neoplasms, Experimental; Methylnitrosourea; Middle Aged; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Tumor Suppressor Protein p53 | 2007 |
Increased antitumor potential of the raloxifene prodrug, raloxifene diphosphate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents, Hormonal; Biological Availability; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cell Proliferation; Estrogen Receptor Modulators; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Organophosphates; Phosphorylation; Prodrugs; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Transplantation, Heterologous | 2008 |
Oral glutamine prevents DMBA-induced mammary carcinogenesis via upregulation of glutathione production.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Disease Models, Animal; Female; Glutamine; Glutathione; Killer Cells, Natural; Mammary Neoplasms, Experimental; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors; Up-Regulation | 2008 |
beta-Ionone suppresses mammary carcinogenesis, proliferative activity and induces apoptosis in the mammary gland of the Sprague-Dawley rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Body Weight; Carcinogens; Cell Proliferation; Cyclin D1; Female; Mammary Neoplasms, Experimental; Norisoprenoids; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 2008 |
Selenium inhibition of the neoplastic transformation in preneoplastic mammary cell populations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Diet; Female; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Precancerous Conditions; Selenium; Time Factors | 1984 |
Tyrosine protein kinase activity in the DMBA-induced rat mammary tumor: inhibition by quercetin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiotensin II; Animals; Cations, Divalent; Cell Membrane; Cyclic AMP; Female; Flavonoids; Kinetics; Mammary Neoplasms, Experimental; Peptide Fragments; Phosphopeptides; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quercetin; Rats | 1984 |
[Influence of calcitonin and ACTH 4-10 on the phenomena of mammary tumor induction by a chemical carcinogen, 7,12-dimethylbenzanthracene].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenocorticotropic Hormone; Animals; Calcitonin; Calcium; Female; Mammary Neoplasms, Experimental; Peptide Fragments; Prolactin; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Biological significance of interstitial collagenase in DMBA-induced mammary tumors of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Extracellular Space; Fluorescent Antibody Technique; Kinetics; Male; Mammary Neoplasms, Experimental; Microbial Collagenase; Rats; Rats, Inbred Strains | 1984 |
[Plasma hormone levels in rats with DMBA-induced mammary tumors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenocorticotropic Hormone; Animals; Estradiol; Female; Growth Hormone; Hormones; Insulin; Luteinizing Hormone; Mammary Neoplasms, Experimental; Prolactin; Rats; Rats, Inbred Strains; Thyrotropin | 1984 |
Scanning electron microscopy of 7,12-dimethylbenz(a)-anthracene-induced mammary carcinoma in the female Sprague-Dawley rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Connective Tissue; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Microscopy, Electron, Scanning; Rats | 1980 |
Pathology of early lesions of mammary carcinoma and mammary dysplasia induced by 7,12-dimethylbenz(a)anthracene in the neonatally androgenized Sprague-Dawley female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Diseases; Female; Fibrocystic Breast Disease; Mammary Neoplasms, Experimental; Progesterone; Rats; Testosterone; Time Factors | 1980 |
Effects of dietary fat and alpha-tocopherol on gamma-glutamyltranspeptidase activity of 7, 12-dimethylbenz(alpha)anthracene-induced mammary gland adenocarcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Dietary Fats; Female; gamma-Glutamyltransferase; Mammary Neoplasms, Experimental; Rats; Vitamin E | 1980 |
Ultrastructure of mammary carcinomas in male rats induced by 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinoma, Adenoid Cystic; Castration; Male; Mammary Neoplasms, Experimental; Microscopy, Electron; Neoplasm Transplantation; Rats; Sex Factors | 1984 |
Gene expression in normal and neoplastic mammary tissue.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Female; Kinetics; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Molecular Weight; Nucleic Acid Hybridization; Poly A; Pregnancy; Protein Biosynthesis; Rabbits; Rats; Reticulocytes; RNA; RNA, Messenger; Transcription, Genetic | 1980 |
Tumor-specific polyadenylated RNA's from 7,12-dimethylbenz(a)anthracene-induced mammary tumors revealed through hybridization with fractionated single-copy DNA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Female; Mammary Neoplasms, Experimental; Nucleic Acid Hybridization; Poly A; Pregnancy; Rats; Rats, Inbred Strains; RNA; RNA, Messenger; RNA, Neoplasm | 1981 |
Effects of hexestrol, medroxyprogesterone acetate and chlormadinone acetate on 7, 12-dimethylbenz [a] anthracene-induced rat mammary cancer in relation to estrogen receptor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Chlormadinone Acetate; Delayed-Action Preparations; Female; Hexestrol; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Rats, Inbred Strains; Receptors, Estrogen | 1981 |
[Cytochemical study of the RNA in rat adenohypophysis cells during mammary carcinogenesis induced by 7-12-dimethyl-(a)-benzanthracene (DMBA)].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Histocytochemistry; Mammary Neoplasms, Experimental; Pituitary Gland, Anterior; Rats; RNA; Time Factors | 1982 |
Isolation and characterization of casein-producing and -nonproducing cell populations from 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Caseins; Cell Membrane; Cell Separation; Centrifugation, Density Gradient; Female; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation; Keratins; Mammary Neoplasms, Experimental; Microscopy, Electron, Scanning; Microvilli; Rats; Rats, Inbred Strains; Receptors, Cell Surface; RNA, Messenger | 1983 |
Influence of dietary content of lipids and lipotropic nutrients on chemical carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Hepatocellular; Cocarcinogenesis; Colonic Neoplasms; Dietary Fats; Estrus; Female; Lipotropic Agents; Liver Neoplasms; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Pregnancy; Rats; Rats, Inbred Strains | 1983 |
Loss of myoepithelial cell characteristics in metastasizing rat mammary tumors relative to their nonmetastasizing counterparts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Epithelial Cells; Fibronectins; Keratins; Laminin; Mammary Neoplasms, Experimental; Mice; Myosins; Neoplasm Metastasis | 1984 |
Characterization of rat mammary tumor cell populations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acids; Animals; Calmodulin; Cells, Cultured; Collagen; Epithelial Cells; Female; Fluorescent Antibody Technique; Keratins; Kinetics; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen | 1984 |
Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumorigenesis by 2,5-di-O-acetyl-D-glucaro-1,4:6,3-dilactone, an in vivo beta-glucuronidase inhibitor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Blood Proteins; Carrier Proteins; Cell Nucleus; Cell-Free System; Cytosol; Female; Glucaric Acid; Glucuronidase; Kinetics; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; RNA; Sugar Acids; Tissue Distribution | 1984 |
Morphological and histological characteristics of mammary dysplasias occurring in cell dissociation-derived murine mammary outgrowths.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; Female; Fibrocystic Breast Disease; Gamma Rays; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasms, Radiation-Induced; Staining and Labeling | 1984 |
Effect of medroxyprogesterone acetate on DMBA-induced rat mammary carcinoma and on immunological reactivity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Immunity; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Mice; Neoplasms, Hormone-Dependent; Rats | 1982 |
Influence of hormones on N-(4-hydroxyphenyl) retinamide inhibition of 7,12-dimethylbenz[alpha]anthracene transformation of mammary cells in organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Cell Transformation, Neoplastic; Estrogens; Female; Fenretinide; Hormones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Progesterone; Tretinoin | 1982 |
Effect of short-term administration of N-(4-hydroxyphenyl)-all-trans-retinamide on chemically induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Tretinoin | 1983 |
[Effect of medroxyprogesterone acetate (MAP) and vitamin C on DMBA induced rat mammary cancer in relation to estrogen receptor(ER)].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Female; Male; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Nandrolone; Rats; Rats, Inbred Strains; Receptors, Estrogen | 1983 |
Combined and sequential treatment using FCE 21336, a new prolactin-lowering drug, and medroxyprogesterone acetate (MPA) in DMBA-induced tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Castration; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Prolactin; Rats; Rats, Inbred Strains | 1984 |
Lack of an effect of dietary retinoids in chemical carcinogenesis of the mouse mammary gland: inverse relationship between mammary tumor cell anaplasia and retinoid efficacy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anaplasia; Animals; Diet; Diterpenes; Female; Fenretinide; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Retinoids; Retinyl Esters; Species Specificity; Tretinoin; Vitamin A | 1984 |
[Changes of hormone receptor status in various treatment for human breast cancer and DMBA tumor of the rat].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Middle Aged; Rats; Receptors, Estrogen; Receptors, Progesterone | 1984 |
Mammary tumorigenesis in 7,12-dimethybenzanthracene-treated C57BL x DBA/2f F1 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Castration; Female; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Hormone-Dependent; Ovary | 1980 |
The relationship of terminal duct hyperplasia to mammary carcinoma in 7,12-dimethylbenz(alpha)anthracene-treated LEW/Mai rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Intraductal, Noninfiltrating; Female; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Lew | 1980 |
Metabolic inhibitors increase prolactin binding to cultured mammary tumor cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bacitracin; Cells, Cultured; Chloroquine; Dinitrophenols; Female; Kinetics; Mammary Neoplasms, Experimental; Prolactin; Rats; Receptors, Cell Surface | 1980 |
Receptor-binding radiopharmaceuticals for imaging breast tumors: estrogen-receptor interactions and selectivity of tissue uptake of halogenated estrogen analogs.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hexestrol; In Vitro Techniques; Isotope Labeling; Mammary Neoplasms, Experimental; Radionuclide Imaging; Rats; Receptors, Estrogen; Sheep; Tissue Distribution; Tritium; Uterus | 1980 |
Effect of hypophysectomy and hormone replacement of hormone receptor levels and the growth of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Hypophysectomy; Mammary Neoplasms, Experimental; Prolactin; Rats; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Progesterone | 1980 |
Levels of cyclic nucleotides in autotransplanted 7, 12-dimethylbenz[a]anthracene-induced rat mammary tumors during their growth and regression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Cyclic AMP; Cyclic GMP; Estrogens; Male; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Nucleotides, Cyclic; Rats; Transplantation, Autologous | 1980 |
Regression of hormone-dependent mammary tumors in Sprague-Dawley rats as a result of tamoxifen or pharmacologic doses of 17 beta-estradiol: cyclic adenosine 3',5'-monophosphate-mediated events.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Cyclic AMP; Estradiol; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Phosphorylation; Protein Kinases; Rats; Tamoxifen | 1981 |
Subset of spleen lymphocytes from BALB/cCrgl mice stimulated by mouse mammary tumor virus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; B-Lymphocytes; Lymphocyte Activation; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Spleen | 1981 |
Lack of relationship between prolactin binding and growth rate of carcinogen-induced mammary tumors or circulating levels of mammotropic hormones in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Progesterone; Prolactin; Rats; Receptors, Cell Surface; Receptors, Prolactin | 1980 |
Regulation of cyclic adenosine 3',5'-monophosphate in relation to growth of dimethylbenz[a]anthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenylyl Cyclases; Animals; Castration; Cyclic AMP; Estrogens; Female; Mammary Neoplasms, Experimental; Phosphoric Diester Hydrolases; Rats | 1980 |
Accelerated mammary cancer development by fetal salivary mesenchyma isografted to adult mouse mammary epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Intraductal, Noninfiltrating; Epidermal Growth Factor; Female; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred Strains; Precancerous Conditions; Salivary Glands; Transplantation, Isogeneic | 1981 |
Partial expression of endogenous mouse mammary tumor virus in mammary tumors induced in BALB/c mice by chemical, hormonal, and physical agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Female; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Pituitary Hormones; RNA, Viral; Time Factors; Urethane; X-Rays | 1981 |
Hormones, chemicals and proviral gene expression as contributing factors during mammary carcinogenesis in C3H/StWi mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Benz(a)Anthracenes; Female; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C3H; Pituitary Hormones; Urethane; Virus Replication | 1981 |
Evidence of separate pathways for viral and chemical carcinogenesis in C3H/StWi mouse mammary glands.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Antigens, Viral; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice | 1980 |
Lack of induction of murine mammary tumor virus expression in cultured mammary glands treated with chemical carcinogens.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Viral; Cells, Cultured; DNA, Viral; Female; Gene Expression Regulation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred Strains; RNA, Viral; Viral Proteins; Virus Activation | 1981 |
[Possible participation of endogenous MMTV virus in chemical carcinogenesis of mouse mammary glands].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Female; Leukemia Virus, Murine; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Vaccination | 1981 |
Effect of an LHRH analog on growth and hormone receptor levels in DMBA-induced mammary tumors in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Female; Gonadotropin-Releasing Hormone; Hormones; Mammary Neoplasms, Experimental; Ovary; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Estrogen; Receptors, FSH; Receptors, LH; Receptors, Progesterone; Receptors, Prolactin; Uterus | 1981 |
Activation of related transforming genes in mouse and human mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; DNA Restriction Enzymes; DNA, Neoplasm; DNA, Viral; Female; Gene Expression Regulation; Humans; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice | 1981 |
Comparison between biochemical and histochemical assessments of peroxidase activity in rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Histocytochemistry; Indicators and Reagents; Isoenzymes; Male; Mammary Neoplasms, Experimental; Peroxidase; Peroxidases; Rats | 1981 |
Organization of proviral DNA and protein composition of hormonally stimulated C57Bl/10 strain-associated mouse mammary tumor virus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; DNA, Viral; Female; Genes, Viral; Hormones; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C57BL; Viral Proteins | 1981 |
Prolactin receptors in cultured rat mammary tumor cells. Unmasking of cell surface receptors by energy depletion.
Topics: 2,4-Dinitrophenol; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Membrane; Cells, Cultured; Dinitrophenols; Energy Metabolism; Kinetics; Male; Mammary Neoplasms, Experimental; Prolactin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Prolactin; Uncoupling Agents | 1982 |
3,4-bis(3'-hydroxyphenyl)hexane--a new mammary tumor-inhibiting compound.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Breast Neoplasms; Castration; Cell Line; Chemical Phenomena; Chemistry; Female; Hexestrol; Humans; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred Strains; Receptors, Estrogen | 1982 |
Comparison of ovariectomy and retinyl acetate on the growth of established 7,12-dimethylbenz[a]anthracene-induced mammary tumors in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Diterpenes; Female; Mammary Neoplasms, Experimental; Progesterone; Prolactin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Estradiol; Receptors, Estrogen; Receptors, Progesterone; Receptors, Prolactin; Retinyl Esters; Time Factors; Vitamin A | 1982 |
A high-tumor-incidence subline of the D1 mouse mammary hyperplastic outgrowth line: effect of carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Cell Line; Disease Susceptibility; Female; Hormones; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Precancerous Conditions; RNA, Viral | 1982 |
Chemical carcinogen activation in the rat mammary gland: intra-organ cell specificity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Organ Specificity; Rats; Rats, Inbred Strains | 1982 |
3,4-bis(3'-hydroxyphenyl)hexane--a new mammary tumor-inhibiting compound. Studies on the mechanism of action on the DMBA-induced, hormone-dependent mammary tumor of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carbohydrate Metabolism; Castration; Female; Hexestrol; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred Strains; Tamoxifen; Uterus | 1982 |
Dibutyryl cyclic AMP treatment mimics ovariectomy: new genomic regulation in mammary tumor regression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bucladesine; Castration; Female; Mammary Neoplasms, Experimental; Protein Biosynthesis; Rats; RNA, Messenger; RNA, Neoplasm | 1982 |
Accelerated appearance of chemically induced mammary carcinomas in obese yellow (Avy/A) (BALB/c X VY) F1 hybrid mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Female; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Obese; Time Factors | 1982 |
Mouse mammary tumor virus proviral sequences congenital to C3H/Sm mice are differentially hypomethylated in chemically induced, virus-induced, and spontaneous mammary tumors.
Topics: 5-Methylcytosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cytosine; DNA Restriction Enzymes; DNA, Neoplasm; DNA, Viral; Female; Gene Amplification; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C3H | 1982 |
Chemical carcinogen-mouse mammary tumor virus interactions in cell transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Calcium; Cell Division; Cell Transformation, Neoplastic; Cell Transformation, Viral; Clone Cells; Cytochalasin B; Epithelium; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Nude; Phenotype | 1983 |
Arrest of hormone-dependent mammary cancer growth in vivo and in vitro by cholera toxin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bucladesine; Castration; Cell Division; Cell Line; Cholera Toxin; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1983 |
Relationship of mammary tumor susceptibility, mammary cell-mediated mutagenesis, and metabolism of polycyclic aromatic hydrocarbons in four types of rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Female; Mammary Neoplasms, Experimental; Mutagens; Mutation; Polycyclic Compounds; Rats; Rats, Inbred F344; Rats, Inbred Strains; Species Specificity | 1983 |
Anticarcinogenic effect of N6,O2'-dibutyryl cyclic adenosine 3':5'-monophosphate on 7,12-dimethylbenz(a)anthracene mammary tumor induction in the rat and its relationship to cyclic adenosine 3':5'-monophosphate metabolism and protein kinase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Bucladesine; Cell Division; Chromatography, DEAE-Cellulose; Cyclic AMP; Female; Mammary Neoplasms, Experimental; Protein Kinases; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Prolactin receptors in explant cultures of carcinogen-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chloroquine; Colchicine; Cycloheximide; Cytochalasin B; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Culture Techniques; Organoids; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Prolactin | 1983 |
Tumor growth-stimulating and inhibiting effects of antiestrogens on the DMBA-induced mammary carcinoma of the ovariectomized, diethylstilbestrol-treated SD rat. A study on the mechanism of action of antiestrogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Cell Division; Diethylstilbestrol; Estrogen Antagonists; Female; Hexestrol; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tamoxifen | 1983 |
Concurrent changes in growth-related biochemical parameters during regression of hormone-dependent rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Cyclic AMP; Dinoprostone; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Phosphoproteins; Prostaglandins E; Rats; Rats, Inbred Strains | 1983 |
Susceptibility of the mammary gland to carcinogenesis. III. The cell of origin of rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinoma, Intraductal, Noninfiltrating; Cell Differentiation; Cell Transformation, Neoplastic; Disease Susceptibility; DNA; Epithelium; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1983 |
In vivo assessment of 99mTc-labeled hematoporphyrin derivative in tumor-bearing animals.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Intraductal, Noninfiltrating; Female; Hematoporphyrin Derivative; Liver Neoplasms; Lung Neoplasms; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Metalloporphyrins; Mice; Neoplasms; Organotechnetium Compounds; Radionuclide Imaging; Rats; Technetium | 1983 |
The lymphocyte activity of adenosine deaminase and enzymes of AMP metabolism in mammary carcinogenesis: the effect of thymostimulin.
Topics: 5'-Nucleotidase; 9,10-Dimethyl-1,2-benzanthracene; Adenosine Deaminase; Adenosine Monophosphate; Adenylate Kinase; AMP Deaminase; Animals; Breast Neoplasms; Cells, Cultured; Female; Humans; Lymphocytes; Mammary Neoplasms, Experimental; Nucleoside Deaminases; Nucleotidases; Precancerous Conditions; Rats; Spleen; Thymus Extracts; Thymus Gland; Time Factors | 1984 |
Effects of bromocriptine and tamoxifen on growth and hormone receptor levels of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Progesterone; Receptors, Prolactin; Tamoxifen | 1983 |
cAMP-independent protein kinase activity is correlated with growth of rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Cyclic AMP; Cytosol; Estradiol; Female; Mammary Neoplasms, Experimental; Protein Kinase Inhibitors; Protein Kinases; Quercetin; Rats; Rats, Inbred Strains | 1984 |
Epithelial organoids and mononuclear phagocytes from DMBA-induced mammary tumors of the rat secrete collagenase in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cells, Cultured; Epithelium; Female; Macrophages; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Microbial Collagenase; Molecular Weight; Monocytes; Phagocytosis; Rats; Rats, Inbred Strains | 1984 |
Oestrogen dependence of lactate dehydrogenase and peroxidase in cell subpopulations of 7,12-dimethylbenz[alpha]anthracene-induced mammary tumours in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Cell Separation; Epithelium; Estrogens; Female; Isoenzymes; L-Lactate Dehydrogenase; Mammary Neoplasms, Experimental; Microscopy, Electron; Peroxidase; Peroxidases; Rats; Rats, Inbred Strains | 1984 |
Vascular reactivity and perfusion characteristics in 7,12-dimethylbenz(a)anthracene-induced rat mammary neoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blood Pressure; Cardiac Output; Female; Mammary Neoplasms, Experimental; Perfusion; Rats; Rats, Inbred Strains; Regional Blood Flow; Vascular Resistance | 1983 |
Retinoid feeding, hormone inhibition, and/or immune stimulation and the genesis of carcinogen-induced rat mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Bromocriptine; Cell Division; Diterpenes; Female; Kinetics; Mammary Neoplasms, Experimental; Mycobacterium bovis; Nocardia; Rats; Retinyl Esters; Tamoxifen; Vitamin A | 1983 |
Caffeine and unsaturated fat diet significantly promotes DMBA-induced breast cancer in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Caffeine; Cocarcinogenesis; Dietary Fats; Fats, Unsaturated; Female; Mammary Neoplasms, Experimental; Neoplasms, Multiple Primary; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Selective maintenance of cultured epithelial cells from DMBA-induced mammary tumours by bovine colostrum supplement.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cattle; Cell Division; Colostrum; Culture Media; Female; Kinetics; Mammary Neoplasms, Experimental; Microscopy, Electron; Microscopy, Electron, Scanning; Pregnancy; Rats; Rats, Inbred Strains | 1983 |
Lactate dehydrogenase activity in cell subpopulations of 7,12-dimethylbenz(a)anthracene-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Estrogens; Female; L-Lactate Dehydrogenase; Mammary Neoplasms, Experimental; Microscopy, Electron; Rats; Rats, Inbred Strains | 1983 |
Progression of rat mammary development with age and its relationship to carcinogenesis by a chemical carcinogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Age Factors; Animals; Cell Division; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1983 |
Changes in chromatin composition associated with hormone-dependent mammary tumor regression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Chromatin; DNA, Neoplasm; Female; Histones; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Prolactin; Rats; Rats, Inbred Strains | 1983 |
2-(Hydroxyphenyl)indoles: a new class of mammary tumor inhibiting compounds.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cattle; Cells, Cultured; Chemical Phenomena; Chemistry; Dansyl Compounds; Estradiol Congeners; Estrogen Antagonists; Female; Humans; Indoles; Mammary Neoplasms, Experimental; Methotrexate; Mice; Rats; Rats, Inbred Strains; Uterus | 1983 |
Alteration in gene expression at the onset of hormone-dependent mammary tumor regression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Electrophoresis, Polyacrylamide Gel; Estrogens; Female; Gene Expression Regulation; Mammary Neoplasms, Experimental; Molecular Weight; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA, Neoplasm; Transcription, Genetic | 1983 |
Increased DNA binding of the estrogen receptor in an estrogen-resistant mammary cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Centrifugation, Density Gradient; Cytosol; DNA; Estradiol; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Molybdenum; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone | 1983 |
Effect of pharmacological doses of estrogen on ovary-independent rat mammary carcinoma containing estrogen and progesterone receptors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Castration; Estradiol; Estrogens; Female; Male; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Time Factors | 1983 |
Inhibition of neoplasia by minor dietary constituents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Diet; Drug Interactions; Female; Glutathione Transferase; Mammary Neoplasms, Experimental; Neoplasms; Rats; Rats, Inbred Strains | 1983 |
Selenium and mouse mammary tumorigenesis: an investigation of possible mechanisms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Division; Cell Line; Drug Interactions; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Selenium | 1983 |
Modulation of tumor incidence and possible mechanisms of inhibition of mammary carcinogenesis by dietary antioxidants.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antioxidants; Body Weight; Diet; Dietary Fats; Drug Interactions; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Oxidoreductases; Rats; Rats, Inbred Strains | 1983 |
Modified steroid hormones. 7. 4-Fluoro-17 beta-estradiol: carbon-13 nuclear magnetic resonance, crystal and molecular structure, and biological activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Crystallography; Estradiol; Female; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Rats; Uterus; X-Rays | 1983 |
Doxorubicin-induced ultrastructural and growth changes in primary cultures of 7,12-dimethylbenz[a]anthracene-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Autoradiography; Benz(a)Anthracenes; Cell Survival; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation, Preclinical; Female; Mammary Neoplasms, Experimental; Microscopy, Electron; Mitotic Index; Rats; Rats, Inbred Strains | 1983 |
Effects of cortisol on tRNA methylase activities in rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Female; Hydrocortisone; Kinetics; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; tRNA Methyltransferases | 1983 |
Enhancement by fluphenazine of dimethylbenz[a]-anthracene-induced mammary tumorigenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Drug Synergism; Female; Fluphenazine; Mammary Neoplasms, Experimental; Papilloma; Rats; Rats, Inbred Strains | 1983 |
Correlation of amino acid fucoside labeling patterns with tumorigenicity of mouse mammary epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acids; Animals; Chromatography, Thin Layer; Epithelium; Female; Fucose; Glycosides; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C | 1983 |
Effects of 4-nitroestrone 3-methyl ether on dimethylbenz(a)anthracene-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Estradiol; Estrogen Antagonists; Estrone; Female; Mammary Neoplasms, Experimental; Ovary; Pituitary Gland; Rats; Rats, Inbred Strains; Uterus | 1983 |
Nononcogenic hormone-independent alveoli produced by carcinogens in cultured mouse mammary glands.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Dose-Response Relationship, Drug; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques | 1983 |
Estrogen receptor binding radiopharmaceuticals: II. Tissue distribution of 17 alpha-methylestradiol in normal and tumor-bearing rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tissue Distribution; Uterus | 1983 |
Effects of a new antiestrogen, keoxifene (LY156758), on growth of carcinogen-induced mammary tumors and on LH and prolactin levels.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Drug Evaluation, Preclinical; Estradiol; Estrogen Antagonists; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Piperidines; Prolactin; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Tamoxifen | 1983 |
PAP immunoperoxidase method demonstrating endogenous estrogen in breast carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Estrogens; Female; Humans; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1983 |
Effect of the prostaglandin synthetase inhibitor indomethacin on 7,12-dimethylbenz(a)anthracene-induced mammary tumorigenesis in rats fed different levels of fat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Body Weight; Corticosterone; Cyclooxygenase Inhibitors; Dietary Fats; Female; Indomethacin; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1983 |
In vitro metabolism of 7,12-dimethylbenz[a]anthracene in mammary epithelial cells from rats with different susceptibilities to carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Benz(a)Anthracenes; Chromatography, High Pressure Liquid; Epithelium; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1983 |
Response of 7,12-dimethylbenz(a)anthracene-induced rat mammary tumor cells to tamoxifen, in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Microscopy, Electron; Molecular Weight; Proteins; Rats; Rats, Inbred Strains; Tamoxifen | 1983 |
Breast tumor incidence in rats after partial mammary resection.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinoma, Papillary; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Mastectomy; Rats; Rats, Inbred Strains; Risk; Time Factors | 1983 |
Steroid metabolism and steroid receptors in dimethylbenz(a)anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carbon Radioisotopes; Cytosol; Estradiol; Female; Kinetics; Mammary Neoplasms, Experimental; Progesterone; Rats; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone; Receptors, Steroid; Testosterone | 1983 |
Close correlation between progesterone receptor concentration and hormonal sensitivity in DMBA-induced mammary tumours of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Castration; Cytosol; Estradiol; Estrus; Female; Mammary Neoplasms, Experimental; Pregnancy; Progesterone; Rats; Receptors, Estrogen; Receptors, Progesterone; Uterus | 1983 |
DNA synthesis during hormone-dependent mammary tumor regression in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; DNA Replication; Female; Kinetics; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1983 |
Transplacental action of diethylstilbestrol on mammary carcinogenesis in female rats given one or two doses of 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Diethylstilbestrol; Estradiol; Female; Mammary Neoplasms, Experimental; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Effect of dietary selenium levels on 7,12-dimethylbenzanthracene-induced mouse mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Diet; Female; Glutathione Peroxidase; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Selenium | 1983 |
The effects of ionizing irradiation on the sedimentation coefficient of cytoplasmic steroid receptors in rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Centrifugation, Density Gradient; Cytosol; Female; Mammary Neoplasms, Experimental; Molybdenum; Radiation, Ionizing; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Trypsin | 1983 |
Tissue- and cell-specific casein gene expression. II. Relationship to site-specific DNA methylation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Caseins; Cell Separation; DNA; DNA (Cytosine-5-)-Methyltransferases; Female; Gene Expression Regulation; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Substrate Specificity | 1983 |
Synergistic effect of vitamin E and selenium in the chemoprevention of mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adipose Tissue; Animals; Drug Synergism; Female; Kinetics; Lipid Peroxides; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenium; Vitamin E | 1983 |
Effects of alterations in early hormonal environment on development and hormone dependency of carcinogen-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Castration; Estradiol; Female; Haloperidol; Mammary Neoplasms, Experimental; Ovary; Rats; Rats, Inbred Strains; Tamoxifen | 1983 |
In vitro drug screening and individualized treatment planning for cancer patients.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cells, Cultured; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation, Preclinical; Female; Humans; Mammary Neoplasms, Experimental; Methotrexate; Neoplasms; Rats; Rats, Inbred Strains; Tamoxifen | 1983 |
Caffeine (1,3,7-trimethylxanthine), a temperature promoter of DMBA-induced rat mammary gland carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Caffeine; Cocarcinogenesis; Drug Administration Schedule; Female; Mammary Neoplasms, Experimental; Probability; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Characterization and assay of progesterone-binding components in DMBA-induced rat mammary carcinoma tissue after progesterone administration.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding, Competitive; Cell Nucleus; Cytosol; Female; Kinetics; Mammary Neoplasms, Experimental; Progesterone; Promegestone; Rats; Rats, Inbred Strains; Receptors, Progesterone | 1983 |
Sequential study on the influence of adriamycin on cell proliferation and ultrastructure of cultured mammary tumor cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cell Nucleus; Cells, Cultured; Chromatin; Depression, Chemical; Dose-Response Relationship, Drug; Doxorubicin; Drug Evaluation, Preclinical; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Correlation between inhibitory effect on prolactin secretion and antitumor activity of new ergoline compounds on DMBA-induced tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Embryo Implantation; Ergolines; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Rats, Inbred Strains | 1983 |
Inhibition of rat mammary tumor growth by purified protein A--a potential anti-tumor agent.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antigen-Antibody Complex; Cell Transformation, Neoplastic; Female; Injections, Intravenous; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Staphylococcal Protein A | 1983 |
Experiments on the influence of combined application of N-methylnitrosourea and 7,12-dimethylbenzanthracene in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Benz(a)Anthracenes; Drug Synergism; Female; Injections, Intravenous; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred Strains | 1983 |
[Estradiol receptors in the plasma membranes of cells in hormone-dependent mammary tumors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenylyl Cyclases; Animals; Cell Membrane; Cytoplasm; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estradiol; Receptors, Estrogen | 1983 |
Phenotypic instability of rat mammary tumor epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Cell Line; Clone Cells; Culture Techniques; Epithelium; Female; Mammary Neoplasms, Experimental; Phenotype; Rabbits; Rats; Rats, Inbred WF | 1983 |
Interstitial albumin mass and transcapillary extravasation rate of albumin in DMBA-induced rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Albumins; Animals; Capillary Permeability; Extracellular Space; Female; Lymph; Mammary Neoplasms, Experimental; Pressure; Rats; Rats, Inbred Strains; Serum Albumin, Radio-Iodinated | 1983 |
The measurement of tamoxifen and metabolites in the rat and relationship to the response of DMBA-induced mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen | 1984 |
Inhibition of chemically induced mammary carcinogenesis in rats by short-term exposure to butylated hydroxytoluene (BHT): interrelationships among BHT concentration, carcinogen dose, and diet.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenofibroma; Adrenal Glands; Animals; Butylated Hydroxytoluene; Diet; Dose-Response Relationship, Drug; Female; Hyperplasia; Mammary Neoplasms, Experimental; Rats | 1984 |
The effectiveness of prophylactic subcutaneous mastectomy in Sprague-Dawley rats induced with 7,12-dimethylbenzanthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Mammary Neoplasms, Experimental; Mastectomy; Rats; Rats, Inbred Strains; Risk | 1984 |
Pineal ablation in varying photoperiods and the incidence of 9,10-dimethyl-1,2-benzanthracene induced mammary cancer in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Animals, Newborn; Benz(a)Anthracenes; Disease Susceptibility; Female; Light; Mammary Neoplasms, Experimental; Pineal Gland; Rats; Time Factors | 1984 |
Dual effects of exogenous insulin on DMBA-induced mammary tumorigenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Drug Antagonism; Female; Insulin; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1983 |
Promotion of 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis by high dietary fat in the rat: possible role of intercellular communication.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonic Acid; Arachidonic Acids; Cell Communication; Cell Line; Cricetinae; Cricetulus; Dietary Fats; Female; Linoleic Acid; Linoleic Acids; Lung; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Stearic Acids; Thioguanine; Time Factors | 1984 |
Similarity between trans fat and saturated fat in the modification of rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Corn Oil; Dietary Fats; Fatty Acids; Female; Mammary Neoplasms, Experimental; Oils; Rats; Rats, Inbred Strains; Stereoisomerism | 1984 |
Absence of an effect of dietary corn oil content on plasma prolactin, progesterone, and 17 beta-estradiol in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Corn Oil; Dietary Fats; Estradiol; Estrus; Female; Hematocrit; Kinetics; Male; Mammary Neoplasms, Experimental; Oils; Pregnancy; Progesterone; Prolactin; Rats; Rats, Inbred Strains | 1984 |
Comparison of dietary carbohydrates for promotion of DMBA-induced mammary tumorigenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Body Weight; Dietary Carbohydrates; Drug Synergism; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1984 |
Mammary tumor induction in analbuminemic rats by 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Body Weight; Estrus; Female; Hyperlipidemias; Mammary Neoplasms, Experimental; Pregnancy; Prolactin; Rats; Rats, Mutant Strains; Serum Albumin; Time Factors | 1984 |
Tumor-producing activity of dithranol (anthralin) and two of its 10-acyl analogs in the dorsal skin of female NMRI mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anthracenes; Anthralin; Body Weight; Carcinogens; Female; Leukemia, Experimental; Mammary Neoplasms, Experimental; Mast-Cell Sarcoma; Mice; Skin Neoplasms | 1984 |
Effects of estrogen and prolactin on thymidine kinase isozyme activities in DMBA-induced rat mammary tumor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromatography, DEAE-Cellulose; Chromatography, High Pressure Liquid; Deoxycytosine Nucleotides; Enzyme Activation; Estrogens; Female; Isoenzymes; Mammary Neoplasms, Experimental; Perphenazine; Prolactin; Rats; Rats, Inbred Strains; Thymidine Kinase | 1984 |
Metastatic patterns and properties of tumor cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Female; Mammary Neoplasms, Experimental; Methylcholanthrene; Neoplasm Metastasis; Rats; Rats, Inbred Strains | 1984 |
Dietary seaweed (Laminaria) and mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Diet; Female; Kinetics; Laminaria; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Seaweed; Time Factors | 1984 |
Role of estrogen and prolactin in stimulation of carcinogen-induced mammary tumor development by a high-fat diet.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Castration; Dietary Fats; Estradiol; Female; Haloperidol; Mammary Neoplasms, Experimental; Prolactin; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Inhibition of 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinogenesis by concomitant or postcarcinogen antioxidant exposure.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anisoles; Antioxidants; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Diet; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1984 |
Inhibition of DMBA-induced mammary cancer by the monoterpene d-limonene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cyclohexenes; Drug Antagonism; Female; Limonene; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Terpenes; Time Factors | 1984 |
Effect of varying photoperiods on mammary morphology, DNA synthesis, and hormone profile in female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Cell Transformation, Neoplastic; Darkness; DNA; Estradiol; Female; Light; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Melatonin; Neoplasms, Radiation-Induced; Pregnancy; Prolactin; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Effect of estrogens on DMBA induced breast tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Cell Transformation, Neoplastic; Estradiol; Estriol; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Quality control of steroid receptor assays in The Netherlands.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Female; Humans; Laboratories; Mammary Neoplasms, Experimental; Netherlands; Quality Control; Rats; Receptors, Steroid; Reference Standards | 1984 |
Striatal dopamine-stimulated adenylate cyclase activity reflects susceptibility of rats to 7,12-dimethylbenz[a]anthracene-induced mammary tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenylyl Cyclases; Animals; Corpus Striatum; Dopamine; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Restraint, Physical; Species Specificity | 1984 |
Blood flow and reactivity to noradrenaline in induced and autotransplanted DMBA rat mammary neoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenofibroma; Adenoma; Animals; Female; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Norepinephrine; Rats; Rats, Inbred Strains; Regional Blood Flow | 1984 |
The combined effects of dietary protein and fat on 7,12-dimethylbenz(a)anthracene-induced breast cancer in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Dietary Proteins; Energy Intake; Female; Growth; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Statistics as Topic; Time Factors | 1984 |
[Cumulative effects of lentinan and endocrine therapy on the growth of DMBA-induced mammary tumor in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Animals; Benz(a)Anthracenes; Castration; Cell Survival; Combined Modality Therapy; Female; Histamine; Lentinan; Mammary Neoplasms, Experimental; Polysaccharides; Rats; Rats, Inbred Strains; Tamoxifen | 1984 |
Prolactin levels and molecular heterogeneity in rat strains with high and low incidence of DMBA-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Chromatography, Gel; Disease Susceptibility; Female; Mammary Neoplasms, Experimental; Prolactin; Radioimmunoassay; Rats; Rats, Inbred Strains; Species Specificity | 1984 |
Dietary fat versus caloric content in initiation and promotion of 7,12-dimethylbenz(a)anthracene-induced mammary tumorigenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Energy Intake; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Effect of melatonin on mammary carcinogenesis in intact and pinealectomized rats in varying photoperiods.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Darkness; DNA Replication; Estradiol; Female; Light; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Melatonin; Pineal Gland; Prolactin; Rats | 1984 |
7,12-Dimethylbenz[a]anthracene--DNA adducts in Sprague-Dawley and Long-Evans female rats: the relationship of DNA adducts to mammary cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Chromatography, High Pressure Liquid; DNA; Female; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors; Tissue Distribution | 1984 |
Antiestrogens. 2. Structure-activity studies in a series of 3-aroyl-2-arylbenzo[b]thiophene derivatives leading to [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl] [4-[2-(1-piperidinyl)ethoxy]-phenyl]methanone hydrochloride (LY156758), a remarkably effec
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Piperidines; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Structure-Activity Relationship; Uterus | 1984 |
[Changes in antitumor resistance during chemical carcinogenesis].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Female; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Rats; Time Factors; Transplantation Immunology | 1984 |
Effects of dietary lipid saturation on prolactin secretion, carcinogen metabolism and mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Dietary Fats; Female; Mammary Neoplasms, Experimental; Mixed Function Oxygenases; Perphenazine; Prolactin; Rats; Rats, Inbred Strains | 1984 |
[Anti-tumor effects of adriamycin, 4'-Epi-adriamycin, THP-adriamycin and mitoxantrone on rat mammary cancer induced by 7,12-dimethyl benz (A) anthracene].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthraquinones; Antineoplastic Agents; Doxorubicin; Female; Mammary Neoplasms, Experimental; Mitoxantrone; Rats; Rats, Inbred Strains | 1984 |
Differences in DMBA-induced mammary neoplastic responses in two lines of Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenofibroma; Animals; Female; Histocompatibility Antigens; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Estrogen-dependent plasminogen activator in 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors in vivo and in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Cycloheximide; Dactinomycin; Estrogens; Female; In Vitro Techniques; Mammary Neoplasms, Experimental; Plasminogen Activators; Rats; Rats, Inbred Strains | 1984 |
Effect of arginine on the carcinogenicity of 7,12-dimethylbenz[a]-anthracene and N-methyl-N-nitrosourea.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arginine; Diet; DNA; Female; In Vitro Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred Strains | 1984 |
Similarities and differences in the ultrastructure of two hormone-dependent and one independent human breast carcinoma grown in athymic nude mice: comparison with the rat DMBA-induced tumor and normal secretory mammocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Line; Female; Humans; Lactoperoxidase; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Microscopy, Electron; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Receptors, Estrogen; Transplantation, Heterologous | 1984 |
7,12-Dimethylbenzanthracene induced mammary tumours in Wistar rats by 'air pouch' technique--a new approach.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Castration; Estrogens; Female; Mammary Neoplasms, Experimental; Methods; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Ovary; Rats; Rats, Inbred Strains; Receptors, Estrogen; Time Factors | 1984 |
[Comparative electron microscopic study of spontaneous and DMBA-induced tumors of mouse mammary glands].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Endoplasmic Reticulum; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Microscopy, Electron; Mitochondria | 1984 |
Dose-dependent change in tissue uptake of 17 beta-(16 alpha-[125I]iodo)-estradiol in female rats: application to external imaging of mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Estradiol; Female; Iodine Radioisotopes; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Radionuclide Imaging; Rats; Rats, Inbred Strains; Tissue Distribution | 1984 |
[Effect of ionizing radiation on the sensitivity to hormonal inducers of differentiation in induced mammary cancer in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Diethylstilbestrol; Drug Resistance; Electric Stimulation; Estradiol Congeners; Female; Gamma Rays; Mammary Neoplasms, Experimental; Rats; Time Factors | 1984 |
Effect of antioxidants on the incidence of 7,12-dimethylbenzanthracene-induced mammary tumor in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Butylated Hydroxyanisole; Female; Mammary Neoplasms, Experimental; Rats; Selenium; Vitamin E | 1984 |
Reversal of the promotional effect of high-fat diet on mammary tumorigenesis by subsequent lowering of dietary fat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Dietary Fats; Fatty Acids; Male; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1984 |
Dietary fat and mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Corn Oil; Dietary Fats; Female; Fish Oils; Humans; Mammary Neoplasms, Experimental; Mice; Neoplasms; Oils; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1984 |
Anticancer activity of new nitrosoureas against Walder carcinosarcoma 256 and DMBA-induced mammary cancer of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Bone Marrow; Carcinoma 256, Walker; Carmustine; Drug Evaluation, Preclinical; Female; Lethal Dose 50; Mammary Neoplasms, Experimental; Nitrosourea Compounds; Rats; Streptozocin | 1980 |
Effect of hormone manipulation on oxidation, reduction and sulphurylation of dehydroepiandrosterone and oestrone in DMBA-induced rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenine Nucleotides; Animals; Castration; Dehydroepiandrosterone; Estradiol; Estrone; Female; Mammary Neoplasms, Experimental; Oxidation-Reduction; Progesterone; Rats; Sulfates | 1980 |
Enhanced inhibition of mammary carcinogenesis by combined treatment with N-(4-hydroxyphenyl)retinamide and ovariectomy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Diet; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Time Factors; Tretinoin | 1982 |
Kinetic data of cytoplasmic estradiol receptor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Breast Neoplasms; Cytoplasm; Cytosol; Estradiol; Female; Humans; Kinetics; Lymphoma; Mammary Neoplasms, Experimental; Mathematics; Rats; Rats, Inbred Strains; Receptors, Estradiol; Receptors, Estrogen; Uterus | 1983 |
Distribution of retinoic acid-binding proteins in normal and neoplastic mammary tissues.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Binding, Competitive; Cytosol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Retinol-Binding Proteins; Tretinoin | 1980 |
Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by sodium cyanate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzopyrenes; Cyanates; Female; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Rats; Stomach Neoplasms | 1980 |
Role of prolactin in the promotion of dimethylbenz[a]anthracene-induced mammary tumors by dietary fat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Dietary Fats; Female; Mammary Neoplasms, Experimental; Median Eminence; Pregnancy; Proestrus; Prolactin; Rats | 1980 |
Elevated methylation capacity of selected transfer RNA methyltransferases from 9,10-dimethyl-1,2-benzanthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Guanine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylation; Pregnancy; Rats; Ribonucleosides; RNA, Bacterial; RNA, Transfer; Substrate Specificity; tRNA Methyltransferases | 1980 |
Phospholipase A2 activity in 9,10-dimethyl-1,2-benzanthracene-induced mammary tumors of rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Enzyme Activation; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Phospholipases; Phospholipases A; Phospholipases A2; Pregnancy; Rats | 1980 |
Affinity of phytoestrogens for estradiol-binding proteins and effect of coumestrol on growth of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding, Competitive; Coumarins; Coumestrol; Estradiol; Estrogens, Non-Steroidal; Female; Humans; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Receptors, Estrogen; Uterus | 1980 |
Induction of mammary tumors in aging rats by 7,12-dimethylbenz[a]anthracene: role of DNA synthesis during carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Benz(a)Anthracenes; DNA; DNA, Neoplasm; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats | 1980 |
Inhibition of DNA synthesis by retinyl acetate during chemically induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diterpenes; DNA, Neoplasm; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Rats; Retinyl Esters; Vitamin A | 1980 |
Inhibition of rat mammary carcinogenesis by short dietary exposure to retinyl acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Diterpenes; Female; Mammary Neoplasms, Experimental; Rats; Retinyl Esters; Time Factors; Vitamin A | 1980 |
Induction of mammary dysplasia and mammary carcinoma in neonatally androgenized female rats by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Animals; Animals, Newborn; Benz(a)Anthracenes; Body Weight; Disease Models, Animal; Female; Intubation; Mammary Neoplasms, Experimental; Organ Size; Ovary; Pituitary Gland; Precancerous Conditions; Rats; Testosterone; Time Factors | 1980 |
Aryl hydrocarbon hydroxylase and epoxide hydratase activities: age effects in mammary epithelial cells of Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Age Factors; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Enzyme Induction; Epithelium; Epoxide Hydrolases; Female; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylcholanthrene; Metyrapone; Polycyclic Compounds; Proadifen; Rats | 1980 |
Characteristics of binding to estrogen, androgen, progestin, and glucocorticoid receptors in 7,12-dimethylbenz(a)anthracene-induced mammary tumors and their hormonal control.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Animals; Castration; Cytosol; Dexamethasone; Dihydrotestosterone; Estradiol; Female; Hypophysectomy; Mammary Neoplasms, Experimental; Molecular Weight; Promegestone; Rats; Receptors, Steroid | 1980 |
Interaction of dimethylbenzanthracene and diethylstilbestrol on mammary adenocarcinoma formation in female ACI rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Diethylstilbestrol; Drug Interactions; Female; Mammary Neoplasms, Experimental; Rats | 1980 |
Evaluation of the antitumour activity of the non-steroidal antioestrogen monohydroxytamoxifen in the DMBA-induced rat mammary carcinoma model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Dose-Response Relationship, Drug; Estradiol; Female; Mammary Neoplasms, Experimental; Organ Size; Promegestone; Rats; Tamoxifen; Uterus | 1980 |
Inhibitory effect of Nocardia rubra cell wall skeleton on carcinogen-induced mammary tumorigenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adjuvants, Immunologic; Animals; Cell Wall; Estrus; Female; Mammary Neoplasms, Experimental; Nocardia; Pregnancy; Prolactin; Rats | 1980 |
Effect of pinealectomy and melatonin on mammary tumor growth in Sprague-Dawley rats under different conditions of lighting.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Light; Mammary Neoplasms, Experimental; Melatonin; Pineal Gland; Rats; Time Factors | 1980 |
The effects of neonatal androgenization on mammary gland mitotic rate and susceptibility of carcinogen-induced mammary dysplastigenesis and tumorigenesis in LEW/Mai rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Breast Diseases; Estrus; Female; Fibrocystic Breast Disease; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mitosis; Organ Size; Ovary; Pregnancy; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Testosterone; Vagina | 1980 |
[Inhibitory effect of a thymic polypeptide factor on the development of mammary gland adenocarcinoma induced by 7,12-dimethylbenz(a)anthracene in female rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antineoplastic Agents; Female; Mammary Neoplasms, Experimental; Rats; Thymus Hormones | 1980 |
Binding of catechol estrogens to the estrogen receptor of dimethylbenz(A) anthracene induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Cytosol; Estradiol; Estriol; Estrogens; Female; Hydroxyestrones; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Uterus | 1980 |
Effects of hypothyroidism on the induction and growth of mammary cancer induced by 7,12-dimethylbenz(a)anthracene in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Female; Hypothyroidism; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Propylthiouracil; Rats; Thyroxine; Time Factors; Triiodothyronine | 1980 |
Regulation of estrogen-binding capacity by insulin in 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diabetes Mellitus, Experimental; Female; Injections, Subcutaneous; Insulin; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen | 1980 |
Ability of dietary fat to overcome the resistance of mature female rats to 7,12-dimethylbenz(a)anthracene-induced mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Dietary Fats; Drug Administration Schedule; Female; Mammary Neoplasms, Experimental; Rats | 1980 |
Interactions between dietary fats and antioxidants on DMBA-induced mammary carcinomas and on AAF-induced hyperplastic nodules and hepatomas.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Benz(a)Anthracenes; Butylated Hydroxytoluene; Diet; Dietary Fats; Drug Interactions; Female; Hyperplasia; Liver Neoplasms, Experimental; Mammary Neoplasms, Experimental; Mixed Function Oxygenases; Rats | 1980 |
Estimation of total oestrogen receptors in DMBA-induced rat mammary tumors by exchange of nuclear bound ligand at low temperature; a comparison with rat uterus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Cell Fractionation; Cell Nucleus; Cold Temperature; Estradiol; Female; Ligands; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Uterus | 1980 |
Neurohypophysial-hormone-responsive cell line derived from a dimethylbenzanthracene-induced rat mammary tumour.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetates; Animals; Cell Line; Female; Insulin; Lipid Metabolism; Mammary Neoplasms, Experimental; Oxytocin; Proteins; Rats; Stimulation, Chemical; Vasopressins | 1980 |
[Inhibition of the blastomogenic effect of 7,12-dimethylbenz(a)anthracene in female rats by buformin, diphenin, a polypeptide pineal extract and L-DOPA].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Buformin; Drug Therapy, Combination; Female; Fibroma; Levodopa; Mammary Neoplasms, Experimental; Peptides; Phenytoin; Pineal Gland; Rats | 1980 |
Blood flow and reactivity to noradrenaline in DMBA-induced rat mammary neoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Blood Circulation; Female; Hemodynamics; Liver Circulation; Mammary Neoplasms, Experimental; Muscles; Norepinephrine; Rats; Skin | 1980 |
Retinoid prevents transformation of cultured mammary glands by procarcinogens but not by many activated carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biotransformation; Carcinogens; Cell Transformation, Neoplastic; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Organ Culture Techniques; Retinoids; Vitamin A | 1980 |
Susceptibility of the mammary gland to carcinogenesis. II. Pregnancy interruption as a risk factor in tumor incidence.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Female; Hysterectomy; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Pregnancy; Pregnancy, Animal; Rats; Risk | 1980 |
Heat transfer and blood flow in experimental tumors in rats compared with the circadian temperature rhythm of the body.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Body Temperature Regulation; Carcinoma 256, Walker; Circadian Rhythm; Female; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Peritoneal Cavity; Rats; Regional Blood Flow; Skin; Time Factors | 1980 |
Different chromatographic behaviours on blue sepharose CL-6B of free and estradiol complexed forms of the estrogen receptor from DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Chromatography, Affinity; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Sepharose | 1980 |
Histopathological modifications following immunotherapy with P 40 in rats bearing DMBA-induced mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adjuvants, Immunologic; Animals; Corynebacterium; Female; Immunotherapy; Mammary Neoplasms, Experimental; Rats | 1980 |
Progesterone-stimulated growth of mammary carcinomas induced by 7,12-dimethylbenz[a]anthracene in neonatally androgenized rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Benz(a)Anthracenes; Body Weight; Castration; Female; Injections; Mammary Neoplasms, Experimental; Organ Size; Progesterone; Prolactin; Rats; Testosterone | 1980 |
The effect of norethynodrel-mestranol pretreatment on hepatic metabolism of 7,12-dimethylbenz(a)anthracene in rats and hamsters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzopyrene Hydroxylase; Bile; Cricetinae; Female; In Vitro Techniques; Liver; Mammary Neoplasms, Experimental; Mesocricetus; Mestranol; Methylcholanthrene; Norethynodrel; Rats | 1980 |
Effects of serial passage on the endocrine response and steroid metabolism of a rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Estradiol; Female; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Testosterone; Thymectomy; Transplantation, Isogeneic | 1980 |
[Role of prolactin in the development of mammary gland tumors induced by dimethylbenzanthracene].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Chlorpromazine; Cocarcinogenesis; Female; Mammary Neoplasms, Experimental; Pituitary Gland, Anterior; Prolactin; Rats | 1980 |
Histamine and DNA synthesis as age-related and strain-related factors during rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; DNA; Estrus; Female; Histamine; Histamine Antagonists; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Pregnancy; Rats; Rats, Inbred Strains; Thymidine | 1980 |
The induction of immunologic tolerance in guinea pigs infused with dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma, Papillary; Administration, Topical; Animals; Benz(a)Anthracenes; Dermatitis, Contact; Female; Guinea Pigs; Injections, Intravenous; Male; Mammary Neoplasms, Experimental | 1980 |
Enhancement of mammary tumorigenesis by dietary selenium deficiency in rats with a high polyunsaturated fat intake.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Fatty Acids, Unsaturated; Female; Mammary Neoplasms, Experimental; Rats; Selenium | 1981 |
Characterization of a 7,12-dimethylbenz(alpha)anthracene-induced BALB/c mouse mammary tumor epithelial cell line.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cell Line; Clone Cells; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Microscopy, Electron; RNA, Messenger | 1980 |
16 alpha-[77Br]bromoestradiol-17 beta: a high specific-activity, gamma-emitting tracer with uptake in rat uterus and uterus and induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromine; Estradiol; Female; Mammary Neoplasms, Experimental; Radioisotopes; Rats; Receptors, Estrogen; Steroids, Brominated; Tissue Distribution; Uterus | 1981 |
N-methyl-N-nitrosourea-induced rat mammary tumors. Hormone responsiveness but lack of spontaneous metastasis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Castration; Cytoplasm; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Receptors, Estrogen; Sebaceous Gland Neoplasms | 1981 |
Serum estrogens and estrogen responsiveness in 7,12-dimethylbenz[a]anthracene-induced mammary tumors as influenced by dietary fat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Dietary Fats; Estradiol; Estrogens; Estrone; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Receptors, Estrogen; Receptors, Progesterone | 1981 |
The role of a high-fat diet in enhancing the development of mammary tumors in ovariectomized rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Body Weight; Castration; Cocarcinogenesis; Dietary Fats; Female; Mammary Neoplasms, Experimental; Rats | 1981 |
Insulin receptor levels and magnitude of insulin-induced responses in 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cells, Cultured; DNA Replication; DNA, Neoplasm; Female; Insulin; Mammary Neoplasms, Experimental; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Rats; Receptor, Insulin; RNA, Neoplasm | 1981 |
N-nitrosomethylurea-induced rat mammary tumours as models of human breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rats, Inbred WF | 1981 |
Oestradiol and progesterone receptors in the mammary tissue and tumours of female Holtzman rats following 7,12-dimethylbenz(a)anthracene administration.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenofibroma; Animals; Benz(a)Anthracenes; Castration; Female; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Receptors, Estrogen; Receptors, Progesterone | 1981 |
The influence of dietary fat and non-specific immunotherapy on carcinogen-induced rat mammary adenocarcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adjuvants, Immunologic; Animals; Dietary Fats; Female; Immunotherapy; Mammary Neoplasms, Experimental; Rats | 1981 |
Response to adreno-ovariectomy and/or pituitary grafting of carcinogen-induced mammary tumors in rats with different growth potential.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Animals; Castration; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Pituitary Gland; Rats; Time Factors; Transplantation, Homologous | 1980 |
Effect of oophorectomy on progesterone metabolism in DMBA-induced mammary tumours of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Female; Mammary Neoplasms, Experimental; Oxidoreductases; Progesterone; Rats | 1980 |
Polyunsaturated fatty acids as promoters of mammary carcinogenesis induced in Sprague-Dawley rats by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Dietary Fats; Estrogens; Fatty Acids, Unsaturated; Female; Intubation, Gastrointestinal; Lipid Metabolism; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Phospholipids; Progesterone; Prolactin; Rats | 1981 |
Antitumor activities and estrogen receptor interactions of the metabolites of the antiestrogens C1628 and U23,469 in the 7,12-dimethylbenz(a)anthracene-induced rat mammary tumor system.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding, Competitive; Cytosol; Estradiol; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Naphthalenes; Nitromifene; Organ Size; Peroxidases; Propylene Glycols; Pyrrolidines; Rats; Receptors, Estrogen; Tetrahydronaphthalenes; Uterus | 1981 |
Relationship of hormones to inhibition of mammary tumor development by underfeeding during the "critical period" after carcinogen administration.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Diet; Estradiol; Fasting; Female; Growth Hormone; Haloperidol; Hormones; Mammary Neoplasms, Experimental; Prolactin; Rats; Time Factors | 1981 |
Recovery of transformed nodule and ductal mammary cells from carcinogen-treated C57BL mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Mice; Neoplasm Transplantation; Pituitary Gland; Precancerous Conditions; Transplantation, Homologous | 1981 |
Biological activity of [127I] and [125I] estradiol analogs in vitro and in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Cytosol; Estradiol; Female; In Vitro Techniques; Mammary Neoplasms, Experimental; Mice; Rabbits; Rats; Receptors, Estradiol; Receptors, Estrogen; Uterus | 1981 |
[Influence of miskleron (clofibrate) on the carcinogenic effect of 7,12-dimethylbenz(alpha)anthracene and nitrosomethylurea in female rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Clofibrate; Drug Interactions; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Time Factors | 1981 |
Effects of indole and tryptophan on cytochrome P-450, dimethylnitrosamine demethylase, and arylhydrocarbon hydroxylase activities.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Cricetinae; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Female; Indoles; Male; Mammary Neoplasms, Experimental; Mesocricetus; Microsomes, Liver; Oxidoreductases, N-Demethylating; Rats; Species Specificity; Tryptophan | 1981 |
Causes of age-dependency of mammary tumour induction by carcinogens in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Carcinogens; DNA; Female; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Pregnancy; Rats | 1981 |
Inhibition of mammary tumorigenesis by a reduction of fat intake after carcinogen treatment in young versus adult rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Dietary Fats; Female; Mammary Neoplasms, Experimental; Rats | 1980 |
Influence of lithium on mammary tumor growth in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Lithium; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Transplantation; Rats | 1980 |
Inhibitory effect of levamisole and adriamycin on rat mammary cancer induced by 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Levamisole; Mammary Neoplasms, Experimental; Rats | 1980 |
Prenatal exposure to diethylstilbestrol: ovarian-independent growth of mammary tumors induced by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Castration; Diethylstilbestrol; Female; Mammary Neoplasms, Experimental; Maternal-Fetal Exchange; Ovary; Pregnancy; Prognosis; Rats; Time Factors | 1981 |
Sequential expression of preneoplastic and neoplastic characteristics of mouse mammary epithelial cells transformed in organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Hyperplasia; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Organ Culture Techniques; Precancerous Conditions; Transplantation, Homologous | 1981 |
N-Nitroso-N-methylurea elicits mammary cancer in resistant and sensitive rat strains.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Resistance; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Species Specificity | 1981 |
Influence of chronic prolactin suppression during puberty on the development of dimethylbenz(a)anthracene-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Analysis of Variance; Animals; Bromocriptine; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Sexual Maturation | 1981 |
DMBA is ineffective in inducing breast cancer in feminized male Holtzman rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cyproterone; Female; Feminization; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Pregnancy; Rats; Testosterone | 1981 |
Hormone and drug effects on growth of DMBA mammary tumours and plasma prolactin levels in adreno-ovariectomized rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Animals; Castration; Dose-Response Relationship, Drug; Ergolines; Estradiol; Female; Mammary Neoplasms, Experimental; Perphenazine; Progesterone; Prolactin; Rats | 1981 |
Factors influencing the anticarcinogenic efficacy of selenium in dimethylbenz[a]anthracene-induced mammary tumorigenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Body Weight; Diet; Dietary Fats; Estradiol; Estrone; Estrus; Female; Mammary Neoplasms, Experimental; Pregnancy; Probability; Prolactin; Rats; Selenium | 1981 |
Inhibition of carcinogen-induced neoplasia by sodium cyanate, tert-butyl isocyanate, and benzyl isothiocyanate administered subsequent to carcinogen exposure.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Benz(a)Anthracenes; Cyanates; Dimethylhydrazines; Female; Intestinal Neoplasms; Isocyanates; Isothiocyanates; Mammary Neoplasms, Experimental; Methylhydrazines; Mice; Neoplasms, Experimental; Rats; Thiocyanates; Time Factors | 1981 |
Mammary carcinogenesis in rats fed different amounts and types of fat.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Cocarcinogenesis; Diet; Dietary Fats; Female; Mammary Neoplasms, Experimental; Probability; Prolactin; Rats; Time Factors | 1981 |
Evidence that the effectiveness of antioxidants as inhibitors of 7,12-dimethylbenz(a) anthracene-induced mammary tumors is a function of dietary fat composition.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animal Feed; Animals; Antioxidants; Benz(a)Anthracenes; Diet; Dietary Fats; Fats, Unsaturated; Female; Mammary Neoplasms, Experimental; Rats; Time Factors | 1981 |
Interaction of o,p'-DDT with the estrogen-binding protein (EBP) of DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carrier Proteins; Cytosol; DDT; Estrogens; Female; Kinetics; Mammary Neoplasms, Experimental; Protein Binding; Rats; Receptors, Estrogen | 1981 |
Growth of mammary glands from monodispersed cells and susceptibility to 7,12-dimethylbenz[alpha]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Division; Female; In Vitro Techniques; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Time Factors | 1981 |
Blocking basement membrane collagen deposition inhibits the growth of 7,12-dimethylbenzanthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Basement Membrane; Benz(a)Anthracenes; Collagen; Female; Hydroxyproline; Mammary Neoplasms, Experimental; Rats | 1981 |
Anticarcinogenic effect of selenium in rats treated with dimethylbenz[a]anthracene and fed different levels and types of fat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Body Weight; Carcinogens; Diet; Dietary Fats; Female; Glutathione Peroxidase; Lipid Peroxides; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenium | 1981 |
Selenium-mediated inhibition of 7,12-dimethylbenz[a]anthracene-induced mouse mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogens; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Selenium; Species Specificity; Time Factors | 1981 |
Selenium and the genesis of murine mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Estrone; Female; Mammary Neoplasms, Experimental; Progesterone; Rats; Selenium; Species Specificity | 1981 |
The tumor-inhibiting effect of diethylstilbestrol-3,4-oxide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Body Weight; Diethylstilbestrol; Female; Humans; Male; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasms, Hormone-Dependent; Organ Size; Rats; Uterus | 1981 |
Mammary-tumour incidence in Sprague-Dawley rats treated with 7,12-dimethylbenz(a)anthracene: effect of pregnancy and lack of effect of unilateral lactation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Dose-Response Relationship, Drug; Female; Lactation; Mammary Neoplasms, Experimental; Pregnancy; Pregnancy Complications; Rats; Rats, Inbred Strains; Sexual Maturation | 1981 |
The effect of age on the histopathogenesis of 7,12-dimethylbenz(a)-anthracene-induced mammary tumors in the Lewis rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Benz(a)Anthracenes; Female; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Time Factors | 1980 |
Tumorigenesis of mammary gland by 7,12-dimethylbenz(a)anthracene during pregnancy: relationship with DNA synthesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Division; DNA; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains | 1981 |
Inhibitory effect of human urinary extract on the growth of DMBA-induced mammary tumors in Holtzman rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cell Line; Female; Gonadotropins; Humans; Male; Mammary Neoplasms, Experimental; Peptides; Rats; Rats, Inbred Strains | 1981 |
In vitro LHRH release: correlation with the LH surge and alteration by a mammary carcinogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Estradiol; Female; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Mammary Neoplasms, Experimental; Potassium; Rats | 1981 |
Estradiol binding by intact cells isolated from DMBA-induced mammary tumors of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Binding Sites; Cell Nucleus; Cytosol; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Substrate Specificity | 1981 |
Neoplastic growth of carcinogen-treated mammary transplants as influenced by fat intake of donor and host.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Rats; Rats, Inbred WF; Transplantation, Homologous | 1981 |
Chemoprevention of mammary tumorigenesis by a combined regimen of selenium and vitamin A.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diet; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Risk; Selenium; Time Factors; Vitamin A | 1981 |
Progestogen and oestrogen receptor activity in ovary-dependent and ovary-independent tumours of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Ovary; Rats; Receptors, Estrogen; Receptors, Progesterone | 1981 |
Prophylaxis of mammary neoplasia by selenium supplementation in the initiation and promotion phases of chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Castration; Diet; Female; Mammary Neoplasms, Experimental; Neoplasm Recurrence, Local; Precancerous Conditions; Rats; Rats, Inbred Strains; Selenium; Time Factors | 1981 |
Melatonin inhibition and pinealectomy enhancement of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Circadian Rhythm; Female; Mammary Neoplasms, Experimental; Melatonin; Neoplasms, Hormone-Dependent; Pineal Gland; Prolactin; Rats; Rats, Inbred Strains; Time Factors | 1981 |
Inhibitory action of Asparagus racemosus on DMBA-induced mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Diet; Estradiol; Female; Magnoliopsida; Mammary Neoplasms, Experimental; Plant Extracts; Premedication; Rats | 1981 |
Urinary polyamine excretion during growth and regression of 1,12-dimethylbenz[a]anthracene-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Female; Mammary Neoplasms, Experimental; Polyamines; Putrescine; Rats; Rats, Inbred Strains; Spermidine | 1981 |
Effects of thiotepa on primary cultures of DMBA-induced mammary tumours of rats: kinetics and ultrastructure.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Count; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Microscopy, Electron; Rats; Rats, Inbred Strains; Thiotepa; Thymidine | 1981 |
[Inhibition of the growth of 7,12-dimethylbenz(a)anthracene- and N-nitrosomethylurea-induced mammary gland neoplasms by methionine in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Female; Kidney Neoplasms; Leukemia, Experimental; Mammary Neoplasms, Experimental; Methionine; Methylnitrosourea; Nitrosourea Compounds; Rats; Sebaceous Gland Neoplasms | 1981 |
Influence of prolactin and growth hormone on rat mammary tumors induced by N-nitrosomethylurea.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Ergolines; Female; Growth Hormone; Hypophysectomy; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Pergolide; Prolactin; Rats | 1982 |
Use of blue sepharose for the purification of cytoplasmic estrogen receptors from DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Chromatography, Agarose; Coloring Agents; Cytosol; Kinetics; Mammary Neoplasms, Experimental; Rats; Receptors, Estradiol; Receptors, Estrogen; Sepharose | 1980 |
Effects of neonatally administered-testosterone propionate on the development of target organs of sex hormones and the induction of mammary carcinomas by 7, 8, 12-trimethylbenz (a)anthracene in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Female; Genitalia, Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Testosterone | 1981 |
Sialic acid metabolism in nutritionally modulated mammary gland carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Dietary Fats; Female; Mammary Neoplasms, Experimental; N-Acylneuraminate Cytidylyltransferase; Neuraminidase; Rats; Rats, Inbred Strains; Sialic Acids; Sialyltransferases | 1981 |
Formation and removal of 7,12-dimethylbenz[a]anthracene--nucleic acid adducts in rat mammary epithelial cells with different susceptibility to carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; DNA; Epithelium; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1981 |
Peroxidase activity in mammary tumors - effect of tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cytosol; Female; Mammary Neoplasms, Experimental; Peroxidases; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1981 |
Relation between adrenal function and 7, 12-dimethylbenz[a]-anthracene-induced mammary cancer of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex Hormones; Adrenal Glands; Aging; Animals; Female; Mammary Neoplasms, Experimental; Rats | 1981 |
Comparison of the effect of butylated hydroxytoluene on N-nitrosomethylurea and 7,12-dimethylbenz[a]-anthracene-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Body Weight; Butylated Hydroxytoluene; Diet; Drug Interactions; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats; Rats, Inbred Strains | 1981 |
Serum cholesterol and 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Body Weight; Cholesterol; Cholesterol, Dietary; Diet; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1981 |
Effect of retinyl acetate on the occurrence of ovarian hormone-responsive and -nonresponsive mammary cancers in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Castration; Diet; Diterpenes; Female; Mammary Neoplasms, Experimental; Ovarian Neoplasms; Rats; Rats, Inbred Strains; Retinyl Esters; Time Factors; Vitamin A | 1982 |
Interaction of dietary fat and the thymus in the induction of mammary tumors by 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Corticosterone; Dietary Fats; Erythrocyte Count; Estrus; Female; Mammary Neoplasms, Experimental; Pregnancy; Prolactin; Rats; Rats, Inbred Strains; Thymectomy; Thymosin; Thymus Gland | 1982 |
Hormonal induction of casein gene expression limited to a small subpopulation of 7,12-dimethylbenz(a)anthracene-induced mammary tumor cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Caseins; Female; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Pregnancy; Rats; Rats, Inbred Strains; RNA, Messenger | 1982 |
Effect of ovariectomy on serially transplanted rat mammary tumors induced by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Estradiol; Female; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred F344; Receptors, Estrogen; Time Factors | 1981 |
Origin of malignant adenocarcinoma cell line induced by retrovirus-like particles from DMBA rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Cell Line; Female; Male; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Retroviridae | 1981 |
Vasopressin: action on WRK-1 rat mammary tumor cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Division; Cell Line; Female; Mammary Neoplasms, Experimental; Mitogens; Rats; Vasopressins | 1982 |
2-bromo-alpha-ergocryptine (CB-154) and tamoxifen (ICI 46,474) induced suppression of the genesis of mammary carcinomas in female rats treated with 7,12-dimethylbenzanthracene (DMBA): a comparison.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Drug Synergism; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Precancerous Conditions; Rats; Rats, Inbred Strains; Tamoxifen; Time Factors | 1982 |
Influence of prenatal exposure to diethylstilbestrol on estrogen and progestin binding proteins in uteri and dimethylbenzanthracene- induced mammary tumors of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Diethylstilbestrol; Estradiol; Female; Mammary Neoplasms, Experimental; Pregnancy; Prenatal Exposure Delayed Effects; Promegestone; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Uterus | 1981 |
Potentiation of the thymosin immunoregulatory effect by hypocorticoidism in rats with DMBA-induced carcinogenesis in mammary glands.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adjuvants, Immunologic; Adrenal Cortex Hormones; Adrenalectomy; Animals; Female; Immunity, Cellular; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Thymosin; Thymus Hormones | 1982 |
Biological characteristics and estrogen and progesterone receptors in mammary carcinoma induced in male Sprague-Dawley rats by a series of intragastric intubations of 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Cell Division; Estradiol; Female; Male; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Rats; Receptors, Estrogen; Receptors, Progesterone; Sex Factors | 1982 |
Essential fatty acids in relation to mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Dietary Fats; Fatty Acids, Essential; Female; Humans; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1981 |
Comparative antioestrogen action in experimental breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tamoxifen; Uterus | 1981 |
Effects of aromatase inhibitor 4-hydroxyandrostenedione and other compounds in the 7, 12-dimethylbenz(a)anthracene-induced breast carcinoma model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstatrienes; Androstenedione; Animals; Aromatase Inhibitors; Castration; Estrogens; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Ovary; Oxidoreductases; Rats | 1982 |
Rat mammary tumors from carcinogen-induced nodules and their responsiveness to ovariectomy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Castration; Female; Graft Survival; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred Lew; Transplantation, Isogeneic | 1982 |
Radiotracers binding to estrogen receptors: I: Tissue distribution of 17 alpha-ethynylestradiol and moxestrol in normal and tumor-bearing rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carbon Radioisotopes; Estradiol Congeners; Estrus; Ethinyl Estradiol; Female; Mammary Neoplasms, Experimental; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tissue Distribution; Uterus | 1982 |
Effects of selenium on mouse mammary tumorigenesis and glutathione peroxidase activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Glutathione Peroxidase; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Peroxidases; Selenium | 1981 |
Enhancement of DMBA induced mammary tumours by intermittent whole body hyperthermia (42 degrees C).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Estradiol; Female; Hot Temperature; Mammary Neoplasms, Experimental; Prolactin; Rats; Rats, Inbred Strains; Thyrotropin; Thyroxine | 1981 |
Tumour induction by carcinogens in iron deficient rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Fibrosarcoma; Iron Deficiencies; Mammary Neoplasms, Experimental; Methylcholanthrene; Rats; Rats, Inbred Strains; Sarcoma, Experimental | 1981 |
N,N'-Dialkyl-1,2-bis(hydroxyphenyl)ethylenediamines and N,N-dialkyl-4,5-bis(4-hydroxyphenyl)imidazolidines: syntheses and evaluation of their mammary tumor inhibiting activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Cells, Cultured; Chemical Phenomena; Chemistry; Ethylenediamines; Female; Humans; Imidazoles; Mammary Neoplasms, Experimental; Rats; Receptors, Estradiol; Receptors, Estrogen; Stereoisomerism; Thymidine | 1982 |
Hormone dependence of 7,12-dimethylbenz[a]anthracene-induced mammary tumor growth: correlation with prostaglandin E2 content.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Female; Haloperidol; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Prostaglandins E; Rats; Rats, Inbred Strains | 1982 |
Proliferation of ductal outgrowths by carcinogen-induced rat mammary tumors in gland-free mammary fat pads.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Cell Division; Female; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Ovary; Rats; Rats, Inbred Lew | 1982 |
Growth and differentiation of hyperplastic outgrowths derived from mouse mammary epithelial cells transformed in organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aldosterone; Animals; Cell Division; Cell Transformation, Neoplastic; Epithelium; Hydrocortisone; Hyperplasia; Insulin; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Models, Biological; Organ Culture Techniques; Prolactin | 1982 |
Free amino acid pools of rodent mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Amino Acids; Animals; Arginine; Cystathionine; Female; gamma-Aminobutyric Acid; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Neoplasm Transplantation; Pregnancy; Rats; Rats, Inbred Strains | 1982 |
Modification of mammary carcinogenesis and tissue peroxidation by selenium deficiency and dietary fat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Drug Synergism; Female; Glutathione Peroxidase; Lipid Peroxides; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenium; Zea mays | 1981 |
Effect of an aromatase inhibitor, 1,4,6-androstatriene-3,17-dione, on 7,12-dimethylbenz[a]anthracene-induced mammary tumors in the rat and its mechanism of action in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstatrienes; Animals; Antineoplastic Agents; Aromatase Inhibitors; Female; Follicle Stimulating Hormone; In Vitro Techniques; Luteinizing Hormone; Mammary Neoplasms, Experimental; Ovary; Oxidoreductases; Prolactin; Rats; Rats, Inbred Strains; Time Factors | 1982 |
The effect of ovariectomy on excretion of urinary steroids and tumor growth in rats bearing 7,12-dimethylbenz[a]anthracene-induced mammary cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex Hormones; Androgens; Animals; Castration; Cyclophosphamide; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred Strains; Tegafur | 1982 |
Effects of DL-alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, on the rat mammary tumour induced by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Carboxy-Lyases; Cyclophosphamide; Eflornithine; Female; Mammary Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Rats; Rats, Inbred Strains | 1982 |
A simple method for scanning electron microscope preparation of cells grown in multiwell culture plates.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cells, Cultured; Culture Techniques; Female; Mammary Neoplasms, Experimental; Microscopy, Electron, Scanning; Rats; Rats, Inbred Strains | 1982 |
Therapy of 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinomas with combinations of 5-fluorouracil and 2 alpha-methyldihydrotestosterone propionate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstanols; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fluorouracil; Mammary Neoplasms, Experimental; Mice | 1982 |
Peroxidase content in cell subpopulations of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Histocytochemistry; Mammary Neoplasms, Experimental; Microscopy, Electron; Peroxidases; Rats; Rats, Inbred Strains | 1982 |
1,1,2-triphenylbut-1-enes: relationship between structure, estradiol receptor affinity, and mammary tumor inhibiting properties.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkenes; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Female; In Vitro Techniques; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Rats; Receptors, Estradiol; Receptors, Estrogen; Structure-Activity Relationship; Time Factors | 1982 |
Effects of isoproterenol on mammary gland tumors induced by N-nitroso-N-methylurea and salivary gland tumors induced by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Female; Isoproterenol; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Salivary Gland Neoplasms | 1982 |
Induction of mammary tumors in virgin female BALB/c mice by single low doses of 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C | 1982 |
Effects of progesterone on mammary carcinogenesis when various doses of DMBA were applied directly to rat mammae.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cystadenocarcinoma; Dose-Response Relationship, Drug; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Progesterone; Rats; Rats, Inbred Strains | 1982 |
Interstitial fluid pressure in DMBA-induced rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Extracellular Space; Female; Mammary Neoplasms, Experimental; Pressure; Rats; Rats, Inbred Strains | 1982 |
Microvascular pressures in DMBA-induced rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arterioles; Blood Pressure; Capillaries; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Venules | 1982 |
Influence of underfeeding during the "critical period" or thereafter on carcinogen-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Female; Kinetics; Mammary Neoplasms, Experimental; Nutrition Disorders; Prolactin; Rats; Rats, Inbred Strains | 1982 |
Effect of short-term feeding of sodium selenite on 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Eating; Female; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenious Acid; Selenium | 1982 |
Effect of N,N'-diethyl-1,2-bis(2,6-dichloro-4-hydroxyphenyl)ethylenediamines on the 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Chlorophenols; Cytosol; Ethylenediamines; Female; In Vitro Techniques; Mammary Neoplasms, Experimental; Mice; Organ Size; Rats; Rats, Inbred Strains; Receptors, Estrogen; Uterus | 1982 |
Inhibitory effect of a fat-free diet on mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Benz(a)Anthracenes; Dietary Fats; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Oils; Rats; Rats, Inbred Strains; Zea mays | 1982 |
The prophylaxis of rat and mouse mammary gland tumorigenesis by suppression of prolactin secretion: a reappraisal.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Prolactin; Rats; Rats, Inbred Lew; Rats, Inbred Strains | 1981 |
Incidence, growth and oestradiol-receptor levels of 7, 12-dimethylbenz (alpha) anthracene-induced mammary tumours in rats: effects of neonatal sex steroids and oestradiol implants.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Castration; Estradiol; Female; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estradiol; Receptors, Estrogen; Sex Factors; Testosterone | 1982 |
Effect of continuous light on the incidence of 9,10-dimethyl-1,2-benzanthracene induced mammary tumors in female Holtzman rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Light; Mammary Neoplasms, Experimental; Pineal Gland; Prolactin; Rats; Rats, Inbred Strains | 1982 |
Failure of ascorbic acid to inhibit growth of transplantable and dimethylbenzanthracene induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1982 |
Dietary vitamin E intake and mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diet; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenium; Time Factors; Vitamin E; Vitamin E Deficiency | 1982 |
Mammary carcinoma induced by a series of intragastric intubations of 7,12-dimethylbenz[a]anthracene in gonadectomized female and male Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Female; Intubation, Gastrointestinal; Male; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen | 1982 |
The role of 7, 12 DMBA and three hormones in 7, 12 DMBA-induced rat mammary cancer: three hypotheses.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Estrogens; Female; Mammary Neoplasms, Experimental; Progesterone; Prolactin; Rats; Structure-Activity Relationship | 1982 |
Studies with steroid-fluorescein conjugates on oestrogen target tissues.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding, Competitive; Breast Neoplasms; Female; Fluorescent Dyes; Humans; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Uterus | 1982 |
Dietary fat and DMBA mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Sexual Maturation | 1981 |
Heterogeneity of nucleic acid synthesis in 7, 12-dimethylbenz (A) anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; DNA, Neoplasm; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; RNA, Neoplasm; Thymidine; Uridine | 1982 |
[Effect of sulpiride and castration on mammary carcinogenesis caused by 7,12-dimethylbenzanthracene in the Wistar rat].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Benz(a)Anthracenes; Castration; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Sulpiride | 1982 |
Effects of gamma-linolenic and dihomo-gamma-linolenic acids on 7,12-dimethylbenz(alpha)anthracene-induced mammary tumors in rats.
Topics: 8,11,14-Eicosatrienoic Acid; 9,10-Dimethyl-1,2-benzanthracene; Animals; Colon; Female; gamma-Linolenic Acid; Gastric Mucosa; Linoleic Acid; Linoleic Acids; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Ovary; Phospholipids; Rats; Rats, Sprague-Dawley; Thymus Gland | 1995 |
Comparative pharmacodynamic analysis of TAT-59 and tamoxifen in rats bearing DMBA-induced mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Binding, Competitive; Estradiol; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tamoxifen | 1995 |
Stromal expression of tenascin is inversely correlated to epithelial differentiation of hormone dependent tissues.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Androgens; Animals; Cell Adhesion Molecules, Neuronal; Cell Differentiation; Endometrial Neoplasms; Epithelial Cells; Epithelium; Extracellular Matrix Proteins; Female; Gene Expression Regulation; Hormones; Male; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Prostatic Neoplasms; Rats; Rats, Wistar; Stromal Cells; Tenascin | 1994 |
Chemoprevention of mammary tumor virus-induced and chemical carcinogen-induced rodent mammary tumors by natural plant products.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Areca; beta Carotene; Carcinogens; Carotenoids; Catechin; Curcuma; Female; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C3H; Plant Extracts; Plant Oils; Plants, Medicinal; Rats; Rats, Wistar; RNA-Directed DNA Polymerase | 1994 |
Pharmacokinetics and metabolism of 2-[18F]fluoro-2-deoxy-D-glucose (FDG) in mammary tumors of antiestrogen-treated rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Brain; Chromatography, High Pressure Liquid; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Kinetics; Mammary Neoplasms, Experimental; Myocardium; Rats; Rats, Sprague-Dawley; Skin; Time Factors; Tissue Distribution | 1995 |
Effects of 3-[N-(2-chlorobenzyl)amino]-6-(1H-imidazol-1-yl) pyridazine dihydrochloride on various aromatase enzyme systems and experimental breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Animals; Aromatase; Aromatase Inhibitors; Cattle; Cholesterol; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Female; Hydroxylation; Lethal Dose 50; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Microsomes; Ovary; Placenta; Pregnancy; Pyridazines; Rats; Rats, Sprague-Dawley | 1995 |
Delay of dimethylbenz[a]anthracene-induced mammary tumorigenesis in transgenic mice by apoptosis induced by an unusual mutant p53 protein.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; DNA Replication; Female; Genes, p53; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Pregnancy; Promoter Regions, Genetic; Rats; Transcriptional Activation; Tumor Suppressor Protein p53 | 1995 |
Linear relationship between flux density and tumor co-promoting effect of prolonged magnetic field exposure in a breast cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Dose-Response Relationship, Radiation; Electromagnetic Fields; Female; Humans; Mammary Neoplasms, Experimental; Neoplasms, Radiation-Induced; Rats; Rats, Sprague-Dawley | 1995 |
Efficacy of cancer prevention by high-selenium garlic is primarily dependent on the action of selenium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; DNA Adducts; Female; Garlic; Mammary Neoplasms, Experimental; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Selenium | 1995 |
Genistein suppresses mammary cancer in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Differentiation; Cell Division; Dimethyl Sulfoxide; Female; Genistein; Isoflavones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Pregnancy; Rats; Rats, Sprague-Dawley | 1995 |
Cell proliferation in dimethylbenz(A)anthracene(DMBA)-induced rat mammary carcinoma treated with antiestrogen toremifene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Female; Flow Cytometry; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Toremifene | 1995 |
Inhibitory effects of medroxyprogesterone acetate (MPA) and the pure antiestrogen EM-219 on estrone (E1)-stimulated growth of dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat.
Topics: 17-Hydroxysteroid Dehydrogenases; 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Drug Synergism; Estradiol; Estrenes; Estrogen Antagonists; Estrone; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Neoplasms, Hormone-Dependent; Organ Size; Ovariectomy; Rats; Rats, Sprague-Dawley; Uterus | 1995 |
Underfeeding-induced suppression of mammary tumors: counteraction by estrogen and haloperidol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Dopamine; Estradiol; Female; Food Deprivation; Haloperidol; Hydroxyindoleacetic Acid; Hypothalamus; Mammary Neoplasms, Experimental; Prolactin; Rats; Rats, Sprague-Dawley; Serotonin | 1993 |
Growth inhibition of DMBA-induced rat mammary carcinomas by the antiandrogen flutamide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dihydrotestosterone; Estradiol; Female; Flutamide; Follicle Stimulating Hormone; Luteinizing Hormone; Mammary Neoplasms, Experimental; Organ Size; Ovary; Progesterone; Rats; Rats, Sprague-Dawley; Uterus | 1995 |
The combined effects of dietary fat and estrogen on survival, 7,12-dimethylbenz(a)anthracene-induced breast cancer and prolactin metabolism in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Body Weight; Corn Oil; Dietary Fats; Dose-Response Relationship, Drug; Eating; Estrogens; Fats; Female; Mammary Neoplasms, Experimental; Ovariectomy; Prolactin; Radioimmunoassay; Random Allocation; Rats; Rats, Sprague-Dawley; Survival Rate | 1995 |
Inhibitory effect of a steroidal antiestrogen (EM-170) on estrone-stimulated growth of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat.
Topics: 17-Hydroxysteroid Dehydrogenases; 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Estrogen Antagonists; Estrone; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1995 |
Induction of ductal carcinomas by intraductal administration of 7,12-dimethylbenz(a)anthracene in Wistar rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Ductal, Breast; Disease Models, Animal; Female; Hyperplasia; Incidence; Mammary Neoplasms, Experimental; Rats; Rats, Wistar; Time Factors | 1995 |
Mammary tumor suppression by transforming growth factor beta 1 transgene expression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Aging; Animals; Crosses, Genetic; Enhancer Elements, Genetic; Exons; Female; Globins; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Polymerase Chain Reaction; Promoter Regions, Genetic; Rabbits; Transforming Growth Factor beta | 1995 |
Inositol hexaphosphate and inositol inhibit DMBA-induced rat mammary cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Bone and Bones; Female; Inositol; Mammary Neoplasms, Experimental; Phytic Acid; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Chronic energy restriction versus energy cycling and mammary tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Energy Intake; Female; Insulin; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1995 |
Accumulation of aluminum in cancers of the liver, stomach, duodenum and mammary glands of rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aluminum; Animals; Carcinoma, Hepatocellular; Copper; Disease Models, Animal; Duodenal Neoplasms; Female; Liver Neoplasms; Male; Mammary Neoplasms, Experimental; Methyldimethylaminoazobenzene; Methylnitronitrosoguanidine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reference Standards; Spectrophotometry, Atomic; Stomach Neoplasms; Zinc | 1994 |
A histopathological study on alterations in DMBA-induced mammary carcinogenesis in rats with 50 Hz, 100 muT magnetic field exposure.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Behavior, Animal; Cocarcinogenesis; Electromagnetic Fields; Female; Hyperplasia; Magnetics; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley | 1995 |
Cancer chemoprevention by aliphatic selenocyanates: effect of chain length on inhibition of mammary tumors and DMBA adducts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cyanates; Disease Models, Animal; DNA; DNA Adducts; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 1995 |
The effect of aromatase inhibitor 4-hydroxyandrostenedione on steroid receptors in hormone-dependent tissues of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Aromatase Inhibitors; Estradiol; Female; Mammary Neoplasms, Experimental; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Receptors, Steroid; RNA, Messenger; Uterus | 1995 |
Cancer chemopreventive activity of brassinin, a phytoalexin from cabbage.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Female; Indoles; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Skin Neoplasms; Thiocarbamates | 1995 |
Comparative effects of milk, yogurt, butter, and margarine on mammary tumorigenesis induced by 7,12-dimethylbenz(a)anthracene in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Butter; Dairy Products; Diet; Dose-Response Relationship, Drug; Energy Intake; Female; Mammary Neoplasms, Experimental; Milk; Rats; Rats, Sprague-Dawley; Yogurt | 1994 |
Decreased tumor formation in 7,12-dimethylbenzanthracene-treated stromelysin-1 transgenic mice is associated with alterations in mammary epithelial cell apoptosis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Animals, Suckling; Apoptosis; Cell Division; Female; Lung Neoplasms; Lymphoma; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 3; Metalloendopeptidases; Metaplasia; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Neoplasm Invasiveness; Neoplasm Proteins; Time Factors; Transforming Growth Factor alpha | 1995 |
Neonatal genistein chemoprevents mammary cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Anticarcinogenic Agents; Cell Differentiation; Female; Genistein; Isoflavones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1995 |
Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Cyclohexenes; Dose-Response Relationship, Drug; Eating; Female; Limonene; Mammary Neoplasms, Experimental; Monoterpenes; Rats; Rats, Wistar; Terpenes; Time Factors | 1994 |
Evaluating the response to antioestrogen toremifene treatment in DMBA induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Epithelium; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mitotic Index; Rats; Rats, Sprague-Dawley; Stromal Cells; Toremifene | 1994 |
Failure of high fat diets to promote mammary cancers in spontaneously hypertensive rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Animals; Blood Pressure; Body Weight; Dietary Fats; Disease Susceptibility; Female; Genes, Tumor Suppressor; Heart Rate; Hypertension; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Inbred SHR | 1994 |
Pharmacology of two new very selective antiprogestagens: Org 31710 and Org 31806.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abortifacient Agents, Steroidal; Abortion, Induced; Androgen Antagonists; Animals; Estrenes; Female; Furans; Gonanes; Macaca; Male; Mammary Neoplasms, Experimental; Menstruation-Inducing Agents; Mifepristone; Pregnancy; Progestins; Rats; Receptors, Glucocorticoid; Receptors, Progesterone | 1994 |
Immunocytochemical localization of estrogen receptors in the mammary tissue of female rats: relevance to carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antibodies, Monoclonal; Estrogens; Feasibility Studies; Female; Immunohistochemistry; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Rats; Rats, Sprague-Dawley; Receptors, Estrogen | 1994 |
Somatostatin analogue octreotide enhances the antineoplastic effects of tamoxifen and ovariectomy on 7,12-dimethylbenz(alpha)anthracene-induced rat mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Combined Modality Therapy; Drug Administration Schedule; Drug Synergism; Female; Mammary Neoplasms, Experimental; Octreotide; Organ Size; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, Somatostatin; Tamoxifen; Uterus | 1994 |
Cell loss in dimethylbenz(a)anthracene-induced rat mammary carcinoma treated with toremifene and ovariectomy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Female; Mammary Neoplasms, Experimental; Microscopy, Electron; Ovariectomy; Rats; Rats, Sprague-Dawley; Toremifene | 1994 |
Activity of triphenylselenonium chloride in mammary cancer prevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1994 |
Prevention by dehydroepiandrosterone of the development of mammary carcinoma induced by 7,12-dimethylbenz(a)anthracene (DMBA) in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Drug Implants; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Ovariectomy; Prolactin; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Inhibition of 7,12-dimethylbenzanthracene-induced rat mammary tumor growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley | 1994 |
Effects of progestagens and Org OD14 in in vitro and in vivo tumor models.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Mammary Neoplasms, Experimental; Norpregnenes; Progestins; Rats; Rats, Sprague-Dawley | 1994 |
Antiproliferative effect of the new aromatase inhibitor fadrozole on pre- and postmenopausal models of rat mammary tumor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Fadrozole; Female; Hormones; Mammary Neoplasms, Experimental; Menopause; Ovariectomy; Rats; Rats, Sprague-Dawley | 1994 |
Inhibition of mammary gland carcinogenesis by green tea catechins and other naturally occurring antioxidants in female Sprague-Dawley rats pretreated with 7,12-dimethylbenz[alpha]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antioxidants; Catechols; Ear Neoplasms; Female; Hydrolyzable Tannins; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Phenylpropionates; Phytic Acid; Rats; Rats, Sprague-Dawley; Tea | 1994 |
Binding sites of droloxifene in the cytosol of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumor cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Binding Sites; Chromatography, High Pressure Liquid; Cytosol; Estradiol; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tamoxifen; Tritium; Tumor Cells, Cultured | 1994 |
Potential role of dietary isoflavones in the prevention of cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Division; Diet; Female; Genistein; Humans; Isoflavones; Male; Mammary Neoplasms, Experimental; Plant Proteins, Dietary; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Soybean Proteins; Tumor Cells, Cultured | 1994 |
Bioactivity of selenium from Brazil nut for cancer prevention and selenoenzyme maintenance.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biological Availability; Diet; Female; Glutathione Peroxidase; Iodide Peroxidase; Kidney; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Nuts; Rats; Rats, Sprague-Dawley; Selenium | 1994 |
Comparative abilities of athymic nude mice and severe combined immune deficient (SCID) mice to accept transplants of induced rat mammary carcinomas: enhanced transplantation efficiency of those rat mammary carcinomas that have elevated expression of neu o
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Intraductal, Noninfiltrating; Estrogens; Female; Gene Expression Regulation, Neoplastic; Male; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Mice, SCID; Neoplasm Transplantation; Progesterone; Proto-Oncogene Proteins; Rats; Rats, Inbred WF; Rats, Sprague-Dawley; Receptor, ErbB-2; Splenectomy; Transplantation, Heterologous; Whole-Body Irradiation | 1993 |
Increased expression of specific protein tyrosine phosphatases in human breast epithelial cells neoplastically transformed by the neu oncogene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Blotting, Southern; Breast; Cell Division; Cell Transformation, Neoplastic; Epithelium; Female; Gene Expression; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Leukocyte Common Antigens; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Molecular Sequence Data; Oncogenes; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2 | 1993 |
Conjugated linoleic acid suppresses mammary carcinogenesis and proliferative activity of the mammary gland in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Bromodeoxyuridine; Cell Division; DNA; DNA Damage; Dose-Response Relationship, Drug; Female; Linoleic Acids; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Effect of estrone on the growth of 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in the rat: a model of postmenopausal breast cancer.
Topics: 17-Hydroxysteroid Dehydrogenases; 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; Estradiol; Estrone; Female; Humans; Mammary Neoplasms, Experimental; Ovariectomy; Postmenopause; Rats; Rats, Sprague-Dawley; Receptors, Progesterone | 1994 |
Enhancement of the antitumor efficacy of the antiprogestin, onapristone, by combination with the antiestrogen, ICI 164384.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Estradiol; Estrogen Antagonists; Female; Gonanes; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasms, Hormone-Dependent; Organ Size; Ovary; Polyunsaturated Alkamides; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Uterus | 1994 |
Acceleration of mammary neoplasia in transforming growth factor alpha transgenic mice by 7,12-dimethylbenzanthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Aging; Animals; Female; Humans; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Transforming Growth Factor alpha | 1994 |
Infrequent p53 mutations in 7,12-dimethylbenz[a]anthracene-induced mammary tumors in BALB/c and p53 hemizygous mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Genes, p53; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Knockout; Mutagenesis; Precancerous Conditions | 1994 |
Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Isothiocyanates; Mammary Neoplasms, Experimental; Norbornanes; Rats; Rats, Sprague-Dawley; Sulfoxides; Survival Analysis; Thiocyanates | 1994 |
Genetic identification of Mcs-1, a rat mammary carcinoma suppressor gene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromosome Mapping; Female; Genes, Tumor Suppressor; Genetic Markers; In Situ Hybridization, Fluorescence; Mammary Neoplasms, Experimental; Phenotype; Rats; Rats, Inbred Strains | 1994 |
Insulin like growth factor-I independence in rat mammary carcinoma cells: a dominant phenotype in somatic cell hybrid experiments.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Division; Humans; Hybrid Cells; Insulin; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Phenotype; Rats; Tumor Cells, Cultured | 1993 |
Antitumour activity of coumarin and 7-hydroxycoumarin against 7,12-dimethylbenz[a]anthracene-induced rat mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Coumarins; Drug Evaluation, Preclinical; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Tamoxifen; Time Factors; Umbelliferones | 1994 |
Influence of esculetin on incidence, proliferation, and cell kinetics of mammary carcinomas induced by 7,12-dimethylbenz[a]anthracene in rats on high- and low-fat diets.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Dietary Fats; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Time Factors; Umbelliferones | 1993 |
Menhaden, coconut, and corn oils and mammary tumor incidence in BALB/c virgin female mice treated with DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Analysis of Variance; Animals; Body Weight; Chi-Square Distribution; Coconut Oil; Cocos; Corn Oil; Dietary Fats, Unsaturated; Eating; Fatty Acids, Omega-3; Female; Fish Oils; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Plant Oils; Random Allocation | 1993 |
Controlled release low dose medroxyprogesterone acetate (MPA) inhibits the development of mammary tumors induced by dimethyl-benz(a) anthracene in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Injections, Subcutaneous; Lactic Acid; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley | 1993 |
Antineoplastic activity and tolerability of a novel heterocyclic alkylphospholipid, D-20133.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cell Differentiation; Female; Ferrets; Mammary Neoplasms, Experimental; Phosphorylcholine; Piperidines; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured; Vomiting | 1993 |
William L. McGuire Memorial Symposium. 1,25(OH)2D3 modulation of mammary tumor cell growth in vitro and in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Breast Neoplasms; Calcitriol; Cell Division; Cell Line; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 1993 |
Aryl hydrocarbon hydroxylase activity in chemically induced and toremifene-treated mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Drug Screening Assays, Antitumor; Female; Liver; Lung; Mammary Glands, Animal; Mammary Neoplasms, Experimental; NADPH-Ferrihemoprotein Reductase; Rats; Rats, Sprague-Dawley; Toremifene; Uterus | 1994 |
[Increased activity of choline kinase in human breast cancer and 7, 12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary carcinoma, and activated by 17 beta-estradiol: preliminary report].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Choline Kinase; Estradiol; Female; Humans; Mammary Neoplasms, Experimental; Rats | 1993 |
Inhibition of rat mammary carcinogenesis by inositol hexaphosphate (phytic acid). A pilot study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Chi-Square Distribution; Female; Mammary Neoplasms, Experimental; Phytic Acid; Pilot Projects; Rats; Rats, Sprague-Dawley | 1993 |
Physiological bases of breast cancer prevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Breast; Chorionic Gonadotropin; DNA; Epithelial Cells; Epithelium; Female; Humans; Inhibins; Mammary Neoplasms, Experimental; Ovariectomy; Pregnancy; Rats; Rats, Sprague-Dawley | 1993 |
Experimental down-regulation of intermediate biomarkers of carcinogenesis in mouse mammary epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers; Cell Line; Cell Transformation, Neoplastic; DNA Repair; Down-Regulation; Epithelium; Estradiol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL | 1993 |
The immune system response during development and progression of carcinogen-induced rat mammary tumors: prevention of tumor growth and restoration of immune system responsiveness by thymopentin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cells, Cultured; Female; Immune Tolerance; Immunoglobulin G; Immunophenotyping; Lymphocyte Activation; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-2; Thymopentin; Thymus Gland | 1993 |
The effects of intermittent progesterone upon tamoxifen inhibition of tumor growth in the 7,12-dimethylbenzanthracene rat mammary tumor model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Progesterone; Rats; Rats, Sprague-Dawley; Tamoxifen; Uterus | 1993 |
Comparative effect of inorganic and organic selenocyanate derivatives in mammary cancer chemoprevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biological Availability; Cyanates; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Sodium Selenite | 1994 |
Induction of tamoxifen-dependent rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Division; Cocarcinogenesis; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Rats, Sprague-Dawley; Tamoxifen | 1993 |
The effects of patterned calorie-restricted diets on mammary tumor incidence and plasma endothelin levels in DMBA-treated rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Body Weight; Cocarcinogenesis; Diet; Dietary Fats; Endothelins; Energy Intake; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1993 |
Cell proliferation and prevalence of ras gene mutations in 7,12-dimethylbenz(a)anthracene (DMBA)-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Cell Division; Codon; DNA Replication; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Immunoblotting; Mammary Neoplasms, Experimental; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Polymerase Chain Reaction; Prevalence; Rats; Rats, Sprague-Dawley | 1993 |
Increased mannose 6-phosphate/insulin-like growth factor II receptor and transforming growth factor beta 1 levels during monoterpene-induced regression of mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cyclohexenes; Drug Screening Assays, Antitumor; Female; Limonene; Mammary Neoplasms, Experimental; Rats; Rats, Inbred F344; Receptor, IGF Type 2; Terpenes; Transforming Growth Factor beta | 1993 |
Preclinical studies on the anticancer activity of the somatostatin analog octreotide (SMS 201-995).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Screening Assays, Antitumor; Female; Humans; In Vitro Techniques; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Octreotide; Pancreatic Neoplasms; Rats; Receptors, Somatostatin; Tumor Cells, Cultured | 1993 |
Tumor promotion in a breast cancer model by exposure to a weak alternating magnetic field.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Electromagnetic Fields; Female; Mammary Neoplasms, Experimental; Models, Biological; Palpation; Rats; Rats, Sprague-Dawley | 1993 |
Reduced adriamycin concentration in rat mammary tumors treated previously with hyperthermia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Combined Modality Therapy; Doxorubicin; Female; Hyperthermia, Induced; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1993 |
DMBA-induced mammary tumor growth in rats exhibiting increased or decreased ability to cope with stress due to early postnatal handling or antidepressant treatment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptation, Psychological; Animals; Animals, Newborn; Arousal; Clomipramine; Cocarcinogenesis; Depression; Estrogens; Female; Handling, Psychological; Male; Mammary Neoplasms, Experimental; Pregnancy; Prolactin; Rats; Stress, Psychological | 1993 |
The anti-tumor arotinoid Ro 40-8757 protects bone marrow from the toxic effects of cyclophosphamide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Bone Marrow; Cyclophosphamide; Drug Interactions; Female; Hematopoiesis; Hematopoietic Stem Cells; Mammary Neoplasms, Experimental; Morpholines; Rats; Rats, Sprague-Dawley; Retinoids | 1993 |
De-regulation of endogenous retrotransposons in mouse mammary carcinomas of diverse etiologies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; DNA Transposable Elements; Female; Leukemia Virus, Murine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; RNA, Neoplasm | 1993 |
Inhibition of growth and appearance of estrogen-dependent rat mammary tumors by 10-propargylestr-4-ene-3,17-dione, an aromatase inhibitor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Cell Division; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Estrogens; Estrus; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Pargyline; Rats; Rats, Sprague-Dawley | 1993 |
Mitotic activity, apoptosis and TRPM-2 mRNA expression in DMBA-induced rat mammary carcinoma treated with anti-estrogen toremifene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Blotting, Northern; Clusterin; Glycoproteins; Mammary Neoplasms, Experimental; Mitosis; Molecular Chaperones; Rats; RNA, Messenger; Toremifene | 1993 |
ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Crosses, Genetic; Ethylnitrosourea; Female; Genes, APC; Genetic Predisposition to Disease; Hyperplasia; Male; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Metaplasia; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Point Mutation | 1993 |
Antitumor activity of the aromatase inhibitor FCE 24928 on DMBA-induced mammary tumors in ovariectomized rats treated with testosterone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Androstatrienes; Animals; Aromatase Inhibitors; Drug Screening Assays, Antitumor; Female; Injections, Subcutaneous; Mammary Neoplasms, Experimental; Ovariectomy; Rats; Rats, Sprague-Dawley; Testosterone | 1993 |
Immortalization phenotype dissociated from the preneoplastic phenotype in mouse mammary epithelial outgrowths in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Epithelium; Female; Genes, p53; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Ovariectomy; Phenotype; Precancerous Conditions | 1993 |
Growth inhibition of 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors by controlled-release low-dose medroxyprogesterone acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Delayed-Action Preparations; Female; Follicle Stimulating Hormone; Injections, Subcutaneous; Luteinizing Hormone; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Microspheres; Rats; Rats, Sprague-Dawley | 1992 |
Anti-tumor and endocrine effects of non-steroidal aromatase inhibitors on estrogen-dependent rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aromatase Inhibitors; Estradiol; Female; Letrozole; Luteinizing Hormone; Mammary Neoplasms, Experimental; Molecular Structure; Nitriles; Organ Size; Rats; Rats, Sprague-Dawley; Tetrazoles; Triazoles; Uterus | 1993 |
Inhibitory effect of combined treatment with the aromatase inhibitor exemestane and tamoxifen on DMBA-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Androstadienes; Animals; Antineoplastic Agents; Aromatase Inhibitors; Drug Synergism; Female; Mammary Neoplasms, Experimental; Organ Size; Ovary; Pituitary Gland; Rats; Rats, Sprague-Dawley; Tamoxifen; Uterus | 1993 |
Comparison of the therapeutic effects of a new arotinoid, Ro 40-8757, and all-trans- and 13-cis-retinoic acids on rat breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Disease Models, Animal; Eating; Female; Mammary Neoplasms, Experimental; Morpholines; Rats; Rats, Sprague-Dawley; Retinoids; Tretinoin | 1993 |
Effects of magnetic fields on mammary tumor development induced by 7,12-dimethylbenz(a)anthracene in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Electromagnetic Fields; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1993 |
Determination of estrogen 3-sulfates in biological fluids of mammary tumor-bearing rats by radioimmunoassay.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Estriol; Female; Mammary Neoplasms, Experimental; Radioimmunoassay; Rats; Rats, Sprague-Dawley | 1993 |
Effects of anticarcinogenic monoterpenes on phase II hepatic metabolizing enzymes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cyclohexenes; Diet; Female; Glucuronosyltransferase; Glutathione Transferase; Limonene; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Inbred WF; Rats, Sprague-Dawley; Terpenes | 1993 |
Effects of the luteinizing-hormone-releasing hormone (LHRH) antagonist ramorelix (hoe013) and the LHRH agonist buserelin on dimethylbenz[]anthracene-induced mammary carcinoma: studies with slow-release formulations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Antineoplastic Agents; Buserelin; Delayed-Action Preparations; Female; Gonadotropin-Releasing Hormone; Mammary Neoplasms, Experimental; Molecular Sequence Data; Oligopeptides; Rats; Rats, Sprague-Dawley | 1993 |
Serum cross-reactive thymosin alpha 1 levels in rats during induction of mammary carcinoma with 7,12-dimethylbenz[a]anthracene: short- and long-term effects.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Thymalfasin; Thymosin | 1993 |
Early life affects the risk of developing breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Dietary Fats; Estradiol; Female; Humans; Mammary Neoplasms, Experimental; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Risk Factors | 1995 |
Effect of selenium on lipids and some lipid metabolising enzymes in DMBA induced mammary tumor rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Cholesterol; Lipids; Lipoprotein Lipase; Lipoproteins; Mammary Neoplasms, Experimental; Phosphatidylcholine-Sterol O-Acyltransferase; Rats; Rats, Wistar; Selenium | 1995 |
[Effect of direct current therapy with chemotherapy in 7,12-dimethylbenz[alpha] anthracene (DMBA)-induced rat mammary cancer].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cisplatin; Combined Modality Therapy; Electric Stimulation Therapy; Female; Mammary Neoplasms, Experimental; Rats | 1995 |
Mutations involving the endogenous ecotropic murine leukemia virus in primary mammary carcinomas of BALB/c mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; DNA, Neoplasm; DNA, Viral; Female; Gene Amplification; Leukemia Virus, Murine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mutation; Neoplasms, Hormone-Dependent; Polymorphism, Restriction Fragment Length; Pregnancy | 1996 |
Iron repletion attenuates the protective effects of iron deficiency in DMBA-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Eating; Female; Iron; Iron Deficiencies; Killer Cells, Natural; Macrophages; Mammary Neoplasms, Experimental; Random Allocation; Rats; Rats, Sprague-Dawley; Spleen; Tumor Necrosis Factor-alpha | 1995 |
The effect of dietary fermented milk products and lactic acid bacteria on the initiation and promotion stages of mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Bifidobacterium; Body Weight; Carcinogens; Carcinoma, Adenosquamous; Diet; Disease Models, Animal; Eating; Female; Fermentation; Incidence; Lactobacillus acidophilus; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Risk Factors; Yogurt | 1995 |
Effects of combined and sequential treatment with tamoxifen and the aromatase inhibitor vorozole on 7,12-dimethylbenz(a) anthracene-induced mammary carcinoma in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Carcinogens; Disease Models, Animal; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Ovariectomy; Progesterone; Rats; Rats, Sprague-Dawley; Tamoxifen; Triazoles | 1996 |
Analysis of EGFR, TGF-alpha, neu and c-myc in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mammary tumors using RT-PCR.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinogens; Dietary Fats; DNA Primers; Female; Genes, erbB-1; Genes, erbB-2; Genes, myc; Imidazoles; Mammary Neoplasms, Experimental; Molecular Sequence Data; Polymerase Chain Reaction; Proto-Oncogenes; Rats; Rats, Inbred F344; RNA, Messenger; Transforming Growth Factor alpha | 1995 |
Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumorigenesis and DMBA-DNA adduct formation by curcumin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Curcumin; DNA Adducts; DNA, Neoplasm; Female; Glutathione Transferase; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1996 |
Suppressive effect of iodine on DMBA-induced breast tumor growth in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Female; Growth Inhibitors; Iodine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Rats; Rats, Sprague-Dawley; Thyroid Gland | 1996 |
Inhibition by rosemary and carnosol of 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary tumorigenesis and in vivo DMBA-DNA adduct formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abietanes; Animals; Anticarcinogenic Agents; Carcinogens; DNA; DNA Adducts; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Phenanthrenes; Rats; Rats, Sprague-Dawley; Spices; Triterpenes; Ursolic Acid | 1996 |
The efficacy of conjugated linoleic acid in mammary cancer prevention is independent of the level or type of fat in the diet.
Topics: 8-Hydroxy-2'-Deoxyguanosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Deoxyguanosine; Dietary Fats; Female; Linoleic Acid; Linoleic Acids; Lipid Peroxidation; Mammary Neoplasms, Experimental; Membrane Lipids; Rats; Rats, Sprague-Dawley | 1996 |
Exposure of DMBA-treated female rats in a 50-Hz, 50 microTesla magnetic field: effects on mammary tumor growth, melatonin levels, and T lymphocyte activation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Lymphocyte Activation; Magnetics; Mammary Neoplasms, Experimental; Melatonin; Rats; Rats, Sprague-Dawley; T-Lymphocytes | 1996 |
Study on pineal function and DMBA-induced breast cancer formation in rats during exposure to a 100-mG, 50 Hz magnetic field.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Analysis of Variance; Animals; Carcinogens; Dose-Response Relationship, Drug; Electromagnetic Fields; Female; Mammary Neoplasms, Experimental; Melatonin; Pineal Gland; Random Allocation; Rats; Rats, Sprague-Dawley | 1996 |
In vivo modulators of antibody kinetics.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adjuvants, Immunologic; Animals; Antibodies, Monoclonal; Carcinogens; Carcinoma; Endothelium, Vascular; Female; Immunoconjugates; Immunoglobulin G; Injections, Intralesional; Injections, Intraperitoneal; Interleukin-2; Iodine Radioisotopes; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Neoplasm Transplantation; Neovascularization, Pathologic; Polysorbates; Rats; Receptor Protein-Tyrosine Kinases; Surface-Active Agents; Time Factors; Transplantation, Heterologous | 1996 |
Effects of the phytochemicals, curcumin and quercetin, upon azoxymethane-induced colon cancer and 7,12-dimethylbenz[a]anthracene-induced mammary cancer in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Carcinogens; Colonic Neoplasms; Curcumin; Drug Interactions; Female; Male; Mammary Neoplasms, Experimental; Plant Extracts; Precancerous Conditions; Quercetin; Rats; Rats, Inbred F344; Rats, Sprague-Dawley | 1996 |
Pregnancy-dependent growth of mammary tumors is associated with overexpression of insulin-like growth factor II.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Female; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor II; Mammary Neoplasms, Experimental; Pregnancy; Pregnancy Complications, Neoplastic; Rats; RNA, Messenger; Tumor Cells, Cultured | 1996 |
Prepubertal genistein exposure suppresses mammary cancer and enhances gland differentiation in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Anticarcinogenic Agents; Carcinogens; Corpus Luteum; Dimethyl Sulfoxide; Estrus; Female; Genistein; Isoflavones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Oocytes; Ovarian Follicle; Rats; Rats, Sprague-Dawley; Sexual Maturation; Time Factors | 1996 |
1-(2-Tetrahydrofuryl)-5-fluorouracil in combination with uracil suppresses mammary carcinogenesis and growth of tumors induced with 7,12-dimethylbenz[a]anthracene in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Bromodeoxyuridine; Female; Hormones; Immunohistochemistry; Incidence; Mammary Neoplasms, Experimental; Organ Size; Rats; Rats, Sprague-Dawley; Tegafur; Thymidine Kinase; Thymidylate Synthase; Uracil | 1996 |
Selenium-enriched garlic inhibits the early stage but not the late stage of mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Female; Food, Fortified; Garlic; Kidney; Liver; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Staging; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Selenium; Tissue Distribution | 1996 |
Medroxyprogesterone acetate accelerates the development and increases the incidence of mouse mammary tumors induced by dimethylbenzanthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Base Sequence; Carcinogens; DNA Primers; Drug Synergism; Exons; Female; Genes, ras; Humans; Incidence; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Polymerase Chain Reaction | 1996 |
Impact of dietary fatty acids on 7,12-dimethylbenz[a]anthracene-induced mammary DNA adducts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Corn Oil; Dietary Fats, Unsaturated; DNA Adducts; Fatty Acids; Female; Glutathione Transferase; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Weight Gain | 1996 |
Antitumorigenic effect of a mammalian lignan precursor from flaxseed.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Butylene Glycols; Carcinogens; Dietary Fiber; Female; Lignans; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1996 |
Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juices.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Beverages; Breast Neoplasms; Cell Division; Citrus; Female; Flavanones; Flavonoids; Genistein; Hesperidin; Humans; Isoflavones; Mammary Neoplasms, Experimental; Quercetin; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 1996 |
Lymphocyte mutant frequency in relation to DNA adduct formation in rats treated with tumorigenic doses of the mammary gland carcinogen 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; DNA Adducts; Dose-Response Relationship, Drug; Female; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Spleen; Time Factors | 1996 |
Incidence of p53 and Ha-ras gene mutations in chemically induced rat mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; DNA, Neoplasm; Female; Genes, p53; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Point Mutation; Polymorphism, Single-Stranded Conformational; Rats; Rats, Sprague-Dawley; Species Specificity | 1996 |
A rice protein isolate alters 7,12-dimethylbenz[alpha]anthracene-induced mammary tumor development in female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Caseins; Dietary Proteins; Eating; Estradiol; Female; Liver; Mammary Neoplasms, Experimental; Organ Size; Oryza; Rats; Rats, Sprague-Dawley; Soybean Proteins; Weight Gain | 1996 |
A role for insulin-like growth factor binding protein 5 in the antiproliferative action of the antiestrogen ICI 182780.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Carcinoma; Cell Division; Culture Media, Conditioned; Estradiol; Estrogen Antagonists; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor Binding Protein 5; Mammary Neoplasms, Experimental; Oligonucleotides, Antisense; Rats; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1996 |
Allelic imbalance in mammary carcinomas induced by either 7,12-dimethylbenz[a]anthracene or ionizing radiation in rats carrying genes conferring differential susceptibilities to mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Carcinogens; Chromosomes; Disease Susceptibility; DNA, Neoplasm; Female; Gene Deletion; Genes, ras; Genes, Tumor Suppressor; Genome; Heterozygote; Mammary Neoplasms, Experimental; Mutation; Neoplasms, Radiation-Induced; Phenotype; Rats; Rats, Inbred F344; Rats, Inbred WKY; Species Specificity | 1996 |
Allelotypic and cytogenetic characterization of chemically induced mouse mammary tumors: high frequency of chromosome 4 loss of heterozygosity at advanced stages of progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Carcinogens; Chromosomes; Disease Progression; Female; Gene Deletion; Heterozygote; Karyotyping; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasm Staging; Neoplasm Transplantation | 1996 |
Breast cancer risk in rats fed a diet high in n-6 polyunsaturated fatty acids during pregnancy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blood Glucose; Dietary Fats; Energy Intake; Estrogens; Fatty Acids, Unsaturated; Female; Humans; Insulin; Mammary Neoplasms, Experimental; Pregnancy; Pregnancy Complications, Neoplastic; Rats; Rats, Sprague-Dawley; Risk | 1996 |
Sulfone metabolite of sulindac inhibits mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Drug Screening Assays, Antitumor; Female; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Sulindac | 1997 |
Protective effect of leuprolide acetate on 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Carcinogens; Female; Leuprolide; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
Prevention of preneoplastic mammary lesion development by a novel vitamin D analogue, 1alpha-hydroxyvitamin D5.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcitriol; Calcium; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Hydroxycholecalciferols; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, Calcitriol; Transforming Growth Factor beta; Vitamin D | 1997 |
Chemoprevention of DMBA-induced mammary carcinogenesis in rats by low-dose EPA and DHA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Cell Division; Diet, Fat-Restricted; Dietary Fats; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Nonesterified; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1997 |
Effects of green tea catechins on the progression or late promotion stage of mammary gland carcinogenesis in female Sprague-Dawley rats pretreated with 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Carcinogens; Catechin; Disease Progression; Female; Mammary Neoplasms, Experimental; Neoplasm Staging; Rats; Rats, Sprague-Dawley; Tea | 1997 |
Induction of mammary cancer and lymphoma by multiple, low oral doses of 7,12-dimethylbenz[a]anthracene in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Administration, Oral; Animals; Carcinogens; Codon; DNA Mutational Analysis; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Genes, ras; Lymphoma; Mammary Neoplasms, Experimental; Mice; Mice, Inbred SENCAR; Organ Specificity; Point Mutation; Polymerase Chain Reaction | 1997 |
Influence of selenium on glutathione and some associated enzymes in rats with mammary tumor induced by 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Female; Glutathione; Mammary Neoplasms, Experimental; Rats; Rats, Wistar; Selenium | 1996 |
Laser-photosensitizer assisted immunotherapy: a novel modality for cancer treatment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adjuvants, Immunologic; Animals; Chitin; Chitosan; Female; Indocyanine Green; Lasers; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Photosensitizing Agents; Rats; Rats, Inbred WF; Tumor Cells, Cultured | 1997 |
Effects of lycopene-enriched tomato oleoresin on 7,12-dimethyl-benz[a]anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; beta Carotene; Carotenoids; Drug Screening Assays, Antitumor; Female; Lycopene; Mammary Neoplasms, Experimental; Plant Extracts; Rats; Rats, Sprague-Dawley | 1997 |
Tea, or tea and milk, inhibit mammary gland and colon carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogens; Colonic Diseases; Colonic Neoplasms; Female; Fibroadenoma; Intestinal Mucosa; Male; Mammary Neoplasms, Experimental; Milk; Precancerous Conditions; Quinolines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Tea; Time Factors | 1997 |
Retention of conjugated linoleic acid in the mammary gland is associated with tumor inhibition during the post-initiation phase of carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Genes, ras; Linoleic Acid; Linoleic Acids; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1997 |
Conjugated linoleic acid and linoleic acid are distinctive modulators of mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Arachidonic Acid; Carcinogens; Dietary Fats; Female; Linoleic Acid; Linoleic Acids; Lipid Metabolism; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Phospholipids; Rats; Rats, Sprague-Dawley | 1997 |
Effects of dehydroepiandrosterone and other sex steroid hormones on mammary carcinogenesis by direct injection of 7,12-dimethylbenz(a) anthracene (DMBA) in hyperprolactinemic female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogens; Cocarcinogenesis; Dehydroepiandrosterone; Drug Interactions; Estradiol; Female; Gonadal Steroid Hormones; Hyperprolactinemia; Mammary Neoplasms, Experimental; Pimozide; Progesterone; Rats; Rats, Wistar; Testosterone | 1997 |
Breast cancer risk in rats fed a diet high in n-6 polyunsaturated fatty acids during pregnancy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Dietary Fiber; Energy Intake; Fatty Acids, Unsaturated; Female; Mammary Neoplasms, Experimental; Pregnancy; Pregnancy Complications, Neoplastic; Rats | 1997 |
D-21266, a new heterocyclic alkylphospholipid with antitumour activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 1997 |
Post-initiation inhibitory effects of green tea catechins on 7,12-dimethylbenz[a]anthracene-induced mammary gland carcinogenesis in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Catechin; Dose-Response Relationship, Drug; Female; Liver; Mammary Neoplasms, Experimental; Organ Size; Rats; Rats, Sprague-Dawley; Tea; Time Factors | 1997 |
Comparison of pure inositol hexaphosphate and high-bran diet in the prevention of DMBA-induced rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Dietary Fiber; Drinking; Female; Mammary Neoplasms, Experimental; Minerals; Phytic Acid; Rats; Rats, Sprague-Dawley | 1997 |
Chemopreventive efficacy of anethole trithione, N-acetyl-L-cysteine, miconazole and phenethylisothiocyanate in the DMBA-induced rat mammary cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylcysteine; Anethole Trithione; Animals; Anticarcinogenic Agents; Body Weight; Female; Isothiocyanates; Mammary Neoplasms, Experimental; Miconazole; Rats; Rats, Sprague-Dawley; Time Factors | 1997 |
Inhibition of mammary carcinogenesis in rats by parenteral high-dose vitamin E.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogens; Carcinoma, Papillary; Female; Infusions, Parenteral; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Vitamin E | 1997 |
Prazosin and stress effect on tumoral growth of 7,12-dimethylbenz[A]anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenergic alpha-Antagonists; Animals; Female; Mammary Neoplasms, Experimental; Prazosin; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Stress, Physiological | 1996 |
Maternal handling during pregnancy reduces DMBA-induced mammary tumorigenesis among female offspring.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptation, Psychological; Animals; Animals, Newborn; Arousal; Carcinogens; Female; Handling, Psychological; Incidence; Mammary Neoplasms, Experimental; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Stress, Psychological; Weight Gain | 1997 |
Cancer chemopreventive activity mediated by deguelin, a naturally occurring rotenoid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Carcinogens; Drug Screening Assays, Antitumor; Enzyme Induction; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasms, Experimental; Ornithine Decarboxylase Inhibitors; Rats; Rats, Sprague-Dawley; Skin Neoplasms | 1997 |
The plasticizer benzyl butyl phthalate (BBP) inhibits 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary DNA adduct formation and tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Cytochrome P-450 CYP1A1; DNA Adducts; Female; Glutathione Transferase; Injections, Intraperitoneal; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Phthalic Acids; Rats; Rats, Sprague-Dawley | 1997 |
Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Brassica; Enzyme Induction; Female; Germination; Glucosinolates; Isothiocyanates; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1997 |
A novel in vitro and in vivo breast cancer model for testing inhibitors of estrogen biosynthesis and its action using mammary tumor cells with an activated int-5/aromatase gene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Analysis of Variance; Anastrozole; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Enzyme Inhibitors; Fadrozole; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Ovariectomy; Postmenopause; Triazoles; Tumor Cells, Cultured | 1997 |
Combined effects of dehydroepiandrosterone and EM-800 on bone mass, serum lipids, and the development of dimethylbenz(A)anthracene-induced mammary carcinoma in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaline Phosphatase; Animals; Benzopyrans; Bone Density; Calcium; Carcinogens; Cell Transformation, Neoplastic; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Estradiol; Estrogen Antagonists; Female; Genitalia, Female; Lipids; Luteinizing Hormone; Mammary Neoplasms, Experimental; Organ Size; Phosphorus; Prolactin; Propionates; Random Allocation; Rats; Rats, Sprague-Dawley | 1997 |
Promotion of dimethylbenz[a]anthracene-initiated mammary carcinogenesis by iron in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Carcinogens; Cocarcinogenesis; Female; Fibroadenoma; Iron; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Weight Gain | 1997 |
Chorionic gonadotropin inhibits rat mammary carcinogenesis through activation of programmed cell death.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Apoptosis; Chorionic Gonadotropin; Female; Genes, Tumor Suppressor; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1997 |
Immunoneutralisation of gonadotrophin releasing hormone: a potential treatment for oestrogen-dependent breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Atrophy; Disease Progression; Estradiol; Female; Genitalia, Female; Gonadotropin-Releasing Hormone; Immunization; Immunoglobulin G; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Palpation; Rats; Rats, Sprague-Dawley | 1997 |
Gene expression changes associated with chemically induced rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Amino Acid Sequence; Animals; Base Sequence; Carcinogens; Cloning, Molecular; Colonic Neoplasms; DNA, Neoplasm; Female; Gene Expression; Genetic Markers; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sequence Homology, Amino Acid | 1997 |
Morphological and biochemical status of the mammary gland as influenced by conjugated linoleic acid: implication for a reduction in mammary cancer risk.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Epithelium; Female; Linoleic Acid; Lipids; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Phospholipids; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Specific Pathogen-Free Organisms; Time Factors | 1997 |
Inhibitory effect of the novel anti-estrogen EM-800 and medroxyprogesterone acetate on estrone-stimulated growth of dimethylbenz[a]anthracene-induced mammary carcinoma in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Benzopyrans; Carcinogens; Cell Division; Drug Screening Assays, Antitumor; Estrogen Antagonists; Estrone; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Organ Size; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Uterus; Vagina | 1997 |
Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Breast Neoplasms; Carcinogens; Cell Nucleus; Epithelial Cells; Female; Humans; Mammary Neoplasms, Experimental; NF-kappa B; NF-kappa B p50 Subunit; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-rel; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Transcription Factor RelA; Transcription Factor RelB; Transcription Factors; Tumor Cells, Cultured | 1997 |
Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor beta receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Female; Gene Expression; Humans; Lung; Lung Neoplasms; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Mutation; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Transfection; Transforming Growth Factor beta; Transgenes | 1997 |
Biodistribution of 123I-labeled 4-hydroxytamoxifen derivatives in rats with dimethylbenzanthracene-induced mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Carcinogens; Estrogen Antagonists; Female; Iodine Radioisotopes; Mammary Neoplasms, Experimental; Radiopharmaceuticals; Rats; Rats, Wistar; Tamoxifen; Tissue Distribution | 1997 |
Seasonal influence on 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in Sprague-Dawley rats under controlled laboratory conditions.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Carcinogens; Female; Mammary Neoplasms, Experimental; Melatonin; Palpation; Pineal Gland; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Seasons | 1997 |
Effect of wheat bran fiber on the development of mammary tumors in female intact and ovariectomized rats treated with 7,12-dimethylbenz(a)anthracene and in mice with spontaneously developing mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Dietary Fiber; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Ovariectomy; Ovary; Rats; Rats, Sprague-Dawley; Triticum; Tumor Cells, Cultured | 1998 |
Chemopreventive efficacy of curcumin-free aqueous turmeric extract in 7,12-dimethylbenz[a]anthracene-induced rat mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chemoprevention; Curcuma; Curcumin; Female; Mammary Neoplasms, Experimental; Plant Extracts; Rats; Rats, Sprague-Dawley | 1998 |
Mammary tumours in Sprague-Dawley rats after initiation with DMBA followed by exposure to 50 Hz electromagnetic fields in a promotional scheme.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Dose-Response Relationship, Radiation; Electromagnetic Fields; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1998 |
Ibuprofen-induced inhibition of cyclooxygenase isoform gene expression and regression of rat mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Gene Expression Regulation, Enzymologic; Ibuprofen; Mammary Neoplasms, Experimental; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley | 1998 |
Antitumor effect of L-deprenyl in rats with carcinogen-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Chromatography, High Pressure Liquid; Dopamine; Female; Hypothalamus, Middle; Injections, Intraperitoneal; Mammary Neoplasms, Experimental; Neuroprotective Agents; Norepinephrine; Rats; Rats, Sprague-Dawley; Selegiline; Serotonin; Time Factors | 1998 |
Genistein alters the ontogeny of mammary gland development and protects against chemically-induced mammary cancer in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Division; DNA Adducts; Estrus; Female; Genistein; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1998 |
Prevention of DMBA-induced rat mammary carcinomas comparing leuprolide, oophorectomy, and tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Estrogen Antagonists; Female; Leuprolide; Mammary Neoplasms, Experimental; Ovariectomy; Rats; Rats, Sprague-Dawley; Tamoxifen | 1998 |
Fasting-refeeding stimulates the development of mammary tumors induced by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Fasting; Female; Food; Haloperidol; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1998 |
Acceleration of mammary tumorigenesis by exposure of 7,12-dimethylbenz[a]anthracene-treated female rats in a 50-Hz, 100-microT magnetic field: replication study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Models, Animal; Electromagnetic Fields; Female; Mammary Neoplasms, Experimental; Melatonin; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Research Design | 1998 |
A transgenic mouse model for mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Disease Models, Animal; Disease Susceptibility; Female; Gene Expression; Genes, p53; Genes, ras; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Mutation; Transgenes; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1998 |
Inhibition of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumor growth by aryl hydrocarbon receptor agonists.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Aryl Hydrocarbon Receptor Nuclear Translocator; Benzofurans; Cytochrome P-450 CYP1A1; DNA-Binding Proteins; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Transcription Factors | 1997 |
Synergistic effect of MNU and DMBA in mammary carcinogenesis and H-ras activation in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Drug Synergism; Female; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Point Mutation; Proto-Oncogene Proteins p21(ras); Rats; Rats, Sprague-Dawley | 1997 |
Effects of dietary n-3-to-n-6 polyunsaturated fatty acid ratio on mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Dinoprostone; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Female; Lipid Peroxides; Liver; Mammary Neoplasms, Experimental; Organ Size; Rats; Rats, Sprague-Dawley; Spleen | 1998 |
Additive effects of medroxyprogesterone acetate and 5-fluorouracil derivative on 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Density; Estradiol; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Organ Size; Polymerase Chain Reaction; Progesterone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tegafur; Thymidine Kinase; Thymidylate Synthase; Transcription, Genetic | 1998 |
3,3',4,4'-tetrachlorobiphenyl (TCB) can enhance DMBA-induced mammary carcinogenesis in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Diet, Fat-Restricted; Drug Synergism; Female; Mammary Neoplasms, Experimental; Polychlorinated Biphenyls; Rats; Rats, Sprague-Dawley | 1998 |
Effect of the beta-diketones diferuloylmethane (curcumin) and dibenzoylmethane on rat mammary DNA adducts and tumors induced by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzoates; Carcinogens; Chalcones; Curcumin; DNA Adducts; Female; Liver Neoplasms, Experimental; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1998 |
Black tea and mammary gland carcinogenesis by 7,12-dimethylbenz[a]anthracene in rats fed control or high fat diets.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cocarcinogenesis; Dietary Fats; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Tea | 1998 |
Suppression of mammary-derived growth inhibitor gene expression by growth hormone and insulin-like growth factor I.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carrier Proteins; Fatty Acid Binding Protein 3; Fatty Acid-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Growth Hormone; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Mammary Neoplasms, Experimental; Mice; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide; Receptors, Pituitary Hormone-Regulating Hormone; Recombinant Proteins; RNA, Messenger | 1998 |
Prevention of development of dimethylbenz(a)anthracene (DMBA)-induced mammary tumors in the rat by the new nonsteroidal antiestrogen EM-800 (SCH57050).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrans; Body Weight; Bone and Bones; Bone Density; Estrogen Antagonists; Female; Lipids; Mammary Neoplasms, Experimental; Organ Size; Ovary; Prodrugs; Propionates; Rats; Rats, Sprague-Dawley; Stereoisomerism; Uterus; Vagina | 1998 |
[Direct-current treatment of chemically induced mammary carcinoma in an animal model: MR volumetric assessment of the effect of the therapy].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogens; Disease Models, Animal; Electric Stimulation Therapy; Electrodes; Female; Magnetic Resonance Imaging; Mammary Neoplasms, Experimental; Rats; Rats, Wistar; Remission Induction; Statistics, Nonparametric; Time Factors | 1998 |
Relationship between immune state and tumor growth rate in rats bearing progressive and non-progressive mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinoma, Ductal, Breast; Disease Progression; Erythrocytes; Female; Hemagglutination Tests; Hypersensitivity, Delayed; Immunity, Cellular; Immunization; Macrophage Activation; Macrophages, Peritoneal; Mammary Neoplasms, Experimental; Nitric Oxide; Rats; Rats, Wistar; Reactive Oxygen Species; Sheep | 1998 |
Effect of dietary curcumin and dibenzoylmethane on formation of 7,12-dimethylbenz[a]anthracene-induced mammary tumors and lymphomas/leukemias in Sencar mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzoates; Chalcones; Curcumin; Female; Leukemia, Experimental; Lymphoma; Mammary Neoplasms, Experimental; Mice | 1998 |
No effects of low copper intake on rat mammary tissue superoxide dismutase 1 activity and mammary chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Copper; Diet; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxide Dismutase-1 | 1998 |
Inhibition of DMBA-initiated rat mammary tumour development by 1-O-hexyl-2,3,5-trimethylhydroquinone, phenylethyl isothiocyanate, and novel synthetic ascorbic acid derivatives.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Carcinogens; Cell Transformation, Neoplastic; Chemoprevention; Diet; Female; Hydroquinones; Isothiocyanates; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1998 |
Chemoprevention of DMBA-induced mammary gland carcinogenesis--preventive effects of free oxygen radical scavengers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Calcium Channel Blockers; Carcinogens; Deferoxamine; Female; Free Radical Scavengers; Mammary Neoplasms, Experimental; Organometallic Compounds; Rats; Rats, Sprague-Dawley; Verapamil | 1998 |
Linkage mapping of the Bra, Brb and Brg genes for rat protein phosphatase 2A 55 kDa B-regulatory subunit isotypes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animal Feed; Animals; Base Sequence; Carcinogens; Chromosome Mapping; Crosses, Genetic; DNA Primers; Female; Gene Library; Genetic Markers; Imidazoles; Isoenzymes; Loss of Heterozygosity; Macromolecular Substances; Male; Mammary Neoplasms, Experimental; Molecular Sequence Data; Polymorphism, Genetic; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Rats; Rats, Inbred ACI; Rats, Inbred BN; Rats, Inbred BUF; Rats, Inbred F344; Rats, Inbred Strains; Rats, Sprague-Dawley; Testis | 1998 |
New iodinated progestins as potential ligands for progesterone receptor imaging in breast cancer. Part 2: In vivo pharmacological characterization.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Female; Humans; Iodine Radioisotopes; Ligands; Mammary Neoplasms, Experimental; Nandrolone; Ovary; Progesterone Congeners; Rabbits; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Uterus | 1998 |
Hypomethylation of an exon I estrogen receptor CpG island in spontaneous and carcinogen-induced mammary tumorigenesis in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Carcinogenicity Tests; Carcinogens; Cell Line; CpG Islands; DNA Methylation; Exons; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Estrogen | 1998 |
Dietary genistein: perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Anticarcinogenic Agents; Biological Availability; Carcinogens; Cell Division; Diet; Dose-Response Relationship, Drug; Female; Genistein; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Organ Size; Rats; Rats, Sprague-Dawley; Uterus | 1998 |
A novel aromatase inhibitor, vorozole, shows antitumor activity and a decrease of tissue insulin-like growth factor-I level in 7, 12-dimethylbenz[a]anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents; Aromatase Inhibitors; Enzyme Inhibitors; Female; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Rats; Triazoles | 1999 |
3,3'4,4'-Tetrachlorobiphenyl exhibits antiestrogenic and antitumorigenic activity in the rodent uterus and mammary cells and in human breast cancer cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Binding, Competitive; Breast Neoplasms; Cell Division; Estradiol; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation; Genes, Reporter; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Neoplasms, Hormone-Dependent; Organ Size; Peroxidases; Polychlorinated Biphenyls; Promegestone; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Structure-Activity Relationship; Transfection; Tumor Cells, Cultured; Uterus | 1999 |
Serial transplants of DMBA-induced mammary tumors in Fischer rats as a model system for human breast cancer. VI. The role of different forms of tumor-associated stress for the regulation of pineal melatonin secretion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Biopterins; Breast Neoplasms; Catecholamines; Corticosterone; Disease Models, Animal; Female; Humans; Interferon-gamma; Mammary Neoplasms, Experimental; Melatonin; Pineal Gland; Rats; Rats, Inbred F344 | 1999 |
Resistance to mammary tumorigenesis in Copenhagen rats is associated with the loss of preneoplastic lesions.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Progression; Drug Resistance; Female; Genes, ras; Genes, Tumor Suppressor; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Rats; Rats, Inbred WF | 1999 |
Very low sensitivity of Wistar:Han female rats to chemocarcinogens in mammary carcinogenesis induction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Rats, Wistar | 1998 |
Inhibitory effect of munetone, an isoflavonoid, on 12-O-tetradecanoylphorbol 13-acetate-induced ornithine decarboxylase activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Epidermal Cells; Epidermis; Isoflavones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Ornithine Decarboxylase Inhibitors; Plant Extracts; Tetradecanoylphorbol Acetate | 1999 |
Effect of 26 week magnetic field exposures in a DMBA initiation-promotion mammary gland model in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Cocarcinogenesis; Disease Models, Animal; Electromagnetic Fields; Female; Humidity; Mammary Neoplasms, Experimental; Palpation; Rats; Rats, Sprague-Dawley; Temperature; Time Factors | 1999 |
Effect of vitamin D3 on carcinogen-modified liver enzymes and tumour incidence in experimental rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cholecalciferol; Female; Glutathione Transferase; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1999 |
Chemical carcinogen-induced tumorigenesis in parous, involuted mouse mammary glands.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Parity; Risk Factors | 1999 |
Concurrent deregulation of gelsolin and cyclin D1 in the majority of human and rodent breast cancers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Polyomavirus Transforming; Breast Neoplasms; Cyclin D1; Female; Gelsolin; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Mice, Transgenic; Pregnancy; Protein Biosynthesis; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic | 1999 |
The mechanisms of antitumor effects of luteinizing hormone-releasing hormone agonist (buserelin) in 7, 12-dimethylbenz(a)anthracene-induced rat mammary cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Buserelin; Drug Implants; Estradiol; Female; Gonadotropin-Releasing Hormone; Mammary Neoplasms, Experimental; Organ Size; Ovariectomy; Rats; Rats, Sprague-Dawley; Uterus | 1999 |
The effects of sustained elevated levels of circulating tissue inhibitor of metalloproteinases-1 on the development of breast cancer in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Enzyme-Linked Immunosorbent Assay; Female; Gelatinases; Humans; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 2; Medroxyprogesterone Acetate; Metalloendopeptidases; Mice; Mice, Transgenic; Tissue Inhibitor of Metalloproteinase-1 | 1999 |
Effect of 13 week magnetic field exposures on DMBA-initiated mammary gland carcinomas in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Carcinogens; Cocarcinogenesis; Electromagnetic Fields; Female; Fibroadenoma; Magnetics; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Time Factors | 1999 |
Exposure of Sprague-Dawley rats to a 50-Hertz, 100-microTesla magnetic field for 27 weeks facilitates mammary tumorigenesis in the 7,12-dimethylbenz[a]-anthracene model of breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Carcinogens; Circadian Rhythm; Cocarcinogenesis; Dose-Response Relationship, Drug; Electromagnetic Phenomena; Female; Fibroadenoma; Magnetics; Mammary Neoplasms, Experimental; Melatonin; Models, Biological; Neoplasms, Radiation-Induced; Organ Specificity; Ornithine Decarboxylase; Rats; Rats, Sprague-Dawley; Time Factors | 1999 |
Alterations in ornithine decarboxylase activity in the rat mammary gland after different periods of 50 Hz magnetic field exposure.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cocarcinogenesis; Female; Magnetics; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Melatonin; Ornithine Decarboxylase; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1999 |
Prepubertal exposure to zearalenone or genistein reduces mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Division; Female; Genistein; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Sexual Maturation; Time Factors; Weight Gain; Zearalenone | 1999 |
Benign and malignant mammary tumors induced by DMBA in female Wistar rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Female; Fibroadenoma; Hyperplasia; Incidence; Mammary Neoplasms, Experimental; Papilloma, Intraductal; Rats; Rats, Wistar | 1999 |
Transplacental effects of IgG generated against soluble 53 kDa protein on the splenic lymph system of rat progeny exposed to carcinogen: rate of apoptosis, proliferation of lymphocytes and expression of Fas and Fas ligand proteins.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Division; Fas Ligand Protein; fas Receptor; Female; Immunity, Maternally-Acquired; Immunization, Passive; Immunoglobulin G; Immunohistochemistry; In Situ Nick-End Labeling; Lymphocytes, Tumor-Infiltrating; Mammary Neoplasms, Experimental; Membrane Glycoproteins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Spleen; T-Lymphocytes; Tumor Suppressor Protein p53 | 1999 |
Murine mammary gland carcinogenesis is critically dependent on progesterone receptor function.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Immunohistochemistry; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Progesterone | 1999 |
Inhibition of rat mammary tumorigenesis by human chorionic gonadotropin associated with increased expression of inhibin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chorionic Gonadotropin; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Genes, myc; Humans; Immunohistochemistry; Inhibins; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Proto-Oncogene Proteins c-myc; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcriptional Activation | 1999 |
Increased susceptibility to carcinogen-induced mammary tumors in MMTV-Cdc25B transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; cdc25 Phosphatases; Cell Cycle Proteins; Epithelial Cells; Gene Expression Regulation, Viral; Genetic Predisposition to Disease; Isoenzymes; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred CBA; Mice, Transgenic; Phosphoprotein Phosphatases; Phosphorylation; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Terminal Repeat Sequences; Transgenes | 1999 |
Effect of Siamese cassia leaves on the activities of chemical carcinogen metabolizing enzymes and on mammary gland carcinogenesis in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cassia; Cytochrome P-450 Enzyme System; Enzymes; Female; Male; Mammary Neoplasms, Experimental; Microsomes, Liver; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Rats, Wistar | 1999 |
Wakame seaweed suppresses the proliferation of 7,12-dimethylbenz(a)-anthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Body Weight; Bromodeoxyuridine; Cell Division; Endocrine Glands; Eosine Yellowish-(YS); Female; Hematoxylin; Immunohistochemistry; In Situ Nick-End Labeling; Iodine; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Phaeophyceae; Plant Extracts; Rats; Rats, Sprague-Dawley; Seaweed; Thyroid Gland; Thyroxine; Transforming Growth Factor beta | 1999 |
Consumption of a buckwheat protein extract retards 7,12-dimethylbenz[alpha]anthracene-induced mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Caseins; Diet; Dietary Proteins; Estradiol; Fagopyrum; Female; Mammary Neoplasms, Experimental; Plant Proteins; Rats; Rats, Sprague-Dawley; Time Factors | 1999 |
Bcl-2 expression delays mammary tumor development in dimethylbenz(a)anthracene-treated transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Division; Genes, p53; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Milk Proteins; Proto-Oncogene Proteins c-bcl-2; Transgenes | 1999 |
Selective estrogenic effects of a novel triphenylethylene compound, FC1271a, on bone, cholesterol level, and reproductive tissues in intact and ovariectomized rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bone and Bones; Breast Neoplasms; Cholesterol; Estrogen Antagonists; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Organ Size; Osteoporosis; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Reference Values; Tamoxifen; Toremifene; Transplantation, Heterologous; Tumor Cells, Cultured; Uterus | 2000 |
Maternal exposure to tamoxifen during pregnancy increases carcinogen-induced mammary tumorigenesis among female rat offspring.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Female; Litter Size; Mammary Neoplasms, Experimental; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Tamoxifen; Time Factors; Weight Gain | 2000 |
DNA adduct formation and molecular analysis of in vivo lacI mutations in the mammary tissue of Big Blue rats treated with 7, 12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Substitution; Animals; Animals, Genetically Modified; Carcinogens; Codon; DNA Adducts; DNA Damage; DNA Mutational Analysis; Female; Frameshift Mutation; Lac Operon; Lymphocytes; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mutagens; Mutation; Organ Specificity; Point Mutation; Rats; Spleen | 2000 |
Post-initiation effects of a super critical extract of propolis in a rat two-stage carcinogenesis model in female F344 rats.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carcinogenicity Tests; Carcinogens; Chemoprevention; Colon; Female; Glutathione Transferase; Hyperplasia; Kidney; Liver; Lung; Mammary Neoplasms, Experimental; Nitrosamines; Organ Size; Propolis; Rats; Rats, Inbred F344; Urinary Bladder | 1999 |
Diets containing whey proteins or soy protein isolate protect against 7,12-dimethylbenz(a)anthracene-induced mammary tumors in female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Analysis of Variance; Animals; Anticarcinogenic Agents; Carcinogens; Caseins; Cattle; Chemoprevention; Dietary Proteins; Female; Incidence; Mammary Neoplasms, Experimental; Milk Proteins; Rats; Rats, Sprague-Dawley; Soybean Proteins; Time Factors; Vagina; Weight Gain; Whey Proteins | 2000 |
Prevention of rat mammary carcinoma utilizing leuprolide as an equivalent to oophorectomy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Hormonal; Carcinogens; Disease Models, Animal; Female; Leuprolide; Mammary Neoplasms, Experimental; Ovariectomy; Random Allocation; Rats; Rats, Sprague-Dawley | 1999 |
Effect of constant light on DMBA mammary tumorigenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Circadian Rhythm; Cocarcinogenesis; Darkness; Female; Light; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 2000 |
A ligand of peroxisome proliferator-activated receptor gamma, retinoids, and prevention of preneoplastic mammary lesions.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Carcinogens; Chromans; Estradiol; Female; Ligands; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Precancerous Conditions; Progesterone; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoid X Receptors; Retinoids; Thiazoles; Thiazolidinediones; Transcription Factors; Tretinoin; Troglitazone | 2000 |
A mammary-specific model demonstrates the role of the p53 tumor suppressor gene in tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Aneuploidy; Animals; Carcinogens; Disease Models, Animal; Epithelial Cells; Female; Genes, Tumor Suppressor; Incidence; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Pituitary Gland; Pregnancy; Tumor Suppressor Protein p53 | 2000 |
Inhibition of N-methyl-N-nitrosourea- and 7,12-dimethylbenz[a] anthracene-induced rat mammary tumorigenesis by dietary cholesterol is independent of Ha-Ras mutations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cholesterol, Dietary; Female; Genes, ras; Hydroxymethylglutaryl CoA Reductases; Mammary Neoplasms, Experimental; Methylnitrosourea; Mutation; Rats; Rats, Sprague-Dawley | 2000 |
Antitumor activity of endostatin against carcinogen-induced rat primary mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Antineoplastic Agents; Base Sequence; Carcinogens; Collagen; Collagen Type XVIII; Endostatins; Female; Humans; Mammary Neoplasms, Experimental; Mice; Molecular Sequence Data; Peptide Fragments; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid | 2000 |
DMBA-induced mammary pathologies are angiogenic in vivo and in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Models, Animal; Endothelial Growth Factors; Female; Humans; Lymphokines; Mammary Neoplasms, Experimental; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
Pregnancy induced mammary tumor specific effector cells are present long after parturition in a breast cancer model in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Coculture Techniques; Cytotoxicity, Immunologic; Female; Labor, Obstetric; Mammary Neoplasms, Experimental; Parity; Pregnancy; Pregnancy, Animal; Radiation Effects; Rats; Rats, Sprague-Dawley; Spleen; T-Lymphocytes; Time Factors; Tumor Cells, Cultured | 2000 |
Inhibition by 9alpha-fluoromedoroxyprogesterone acetate (FMPA) against mammary carcinoma induced by dimethylbenz[a]anthracene in rats and angiogenesis in the rabbit cornea - comparison with medroxyprogesterone acetate (MPA).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cornea; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Neovascularization, Pathologic; Progesterone; Rabbits; Rats; Rats, Sprague-Dawley; Time Factors | 2000 |
Melatonin and retinyl acetate as chemopreventives in DMBA-induced mammary carcinogenesis in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Diterpenes; Drug Synergism; Female; Mammary Neoplasms, Experimental; Melatonin; Rats; Rats, Sprague-Dawley; Retinyl Esters; Vitamin A | 2000 |
Biodistribution and breast tumor uptake of 16alpha-[18F]-fluoro-17beta-estradiol in rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Estradiol; Female; Fluorine Radioisotopes; Mammary Neoplasms, Experimental; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tissue Distribution | 2000 |
In vitro and in vivo studies of methylseleninic acid: evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Comet Assay; Female; Glutathione Peroxidase; Liver; Lyases; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasms, Experimental; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Selenium; Thioredoxin-Disulfide Reductase; Tissue Distribution; Tumor Cells, Cultured | 2000 |
Possible mechanisms underlying mammary carcinogenesis in female Wistar rats by nitrofurazone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Infective Agents, Local; Carcinogens; Diestrus; Dose-Response Relationship, Drug; Estradiol; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Mammary Neoplasms, Experimental; Nitrofurazone; Proestrus; Progesterone; Prolactin; Rats; Rats, Wistar; Thyrotropin | 2000 |
Transplacental effects of maternal feeding with high fat diets on lipid exchange and response of the splenic lymphoid system in mice offspring exposed to low doses of carcinogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; B-Lymphocytes; Carcinogens; Corn Oil; Dietary Fats, Unsaturated; Female; Immunohistochemistry; In Situ Nick-End Labeling; Linoleic Acid; Liver; Lymphocyte Activation; Lymphocyte Count; Mammary Neoplasms, Experimental; Maternal-Fetal Exchange; Mice; Mice, Inbred BALB C; Oleic Acid; Olive Oil; Organ Size; Plant Oils; Pregnancy; Spleen; T-Lymphocytes | 2000 |
Serial transplants of DMBA-induced mammary tumors in fischer rats as model system for human breast cancer: V. Myoepithelial-mesenchymal conversion during passaging as possible cause for modulation of pineal-tumor interaction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Adenocarcinoma; Animals; Disease Models, Animal; Epithelium; Female; Humans; Immunohistochemistry; Keratins; Kinetics; Mammary Neoplasms, Experimental; Melatonin; Neoplasm Transplantation; Rats; Rats, Inbred F344 | 2000 |
Anti-tumor effect of L-deprenyl is associated with enhanced central and peripheral neurotransmission and immune reactivity in rats with carcinogen-induced mammary tumors.
Topics: 3,4-Dihydroxyphenylacetic Acid; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Female; Flow Cytometry; Hydroxyindoleacetic Acid; Immune System; Interferon-gamma; Interleukin-2; Killer Cells, Natural; Mammary Neoplasms, Experimental; Monoamine Oxidase Inhibitors; Neuroimmunomodulation; Norepinephrine; Rats; Rats, Sprague-Dawley; Selegiline; Serotonin; Spleen; Sympathetic Nervous System; Synaptic Transmission; T-Lymphocytes | 2000 |
Mammary carcinogenesis induced in Wistar:han rats by the combination of ionizing radiation and dimethylbenz(a)anthracene: prevention with melatonin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Female; Mammary Neoplasms, Experimental; Neoplasms, Radiation-Induced; Rats; Rats, Wistar | 2000 |
Repeated administration of carcinogen in critical developmental periods increases susceptibility of female Wistar: han rats to mammary carcinogenesis induction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Drug Administration Schedule; Female; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Wistar | 2000 |
Post-initiation treatment of rats with indole-3-carbinol or beta-naphthoflavone does not suppress 7, 12-dimethylbenz[a]anthracene-induced mammary gland carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; beta-Naphthoflavone; Body Weight; Cytochrome P-450 Enzyme System; Drug Administration Schedule; Enzyme Induction; Female; Indoles; Isoenzymes; Mammary Neoplasms, Experimental; Microsomes, Liver; Rats; Rats, Sprague-Dawley | 2000 |
Expression of the aryl hydrocarbon receptor/transcription factor (AhR) and AhR-regulated CYP1 gene transcripts in a rat model of mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; RNA, Messenger | 2000 |
Vanadium chemoprevention of 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinogenesis: probable involvement of representative hepatic phase I and II xenobiotic metabolizing enzymes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cytochrome P-450 Enzyme System; Female; Glutathione; Glutathione Transferase; Lipid Peroxidation; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Organ Size; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vanadium; Xenobiotics | 2000 |
Increased expression of cyclin D1, cyclin E and p21(Cip1) associated with decreased expression of p27(Kip1) in chemically induced rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cell Cycle Proteins; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Mammary Neoplasms, Experimental; Microtubule-Associated Proteins; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Proteins | 2000 |
Distinguishing effects on tumor multiplicity and growth rate in chemoprevention experiments.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Biometry; Canthaxanthin; Diterpenes; Drug Screening Assays, Antitumor; Female; Mammary Neoplasms, Experimental; Models, Statistical; Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Retinyl Esters; Vitamin A | 2000 |
Genetic loci controlling breast cancer susceptibility in the Wistar-Kyoto rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Crosses, Genetic; Female; Genes, Tumor Suppressor; Genotype; Humans; Male; Mammary Neoplasms, Experimental; Models, Genetic; Oncogenes; Quantitative Trait, Heritable; Rats; Rats, Inbred WF; Rats, Inbred WKY | 2001 |
Effects of tamoxifen and melatonin on mammary gland cancer induced by N-methyl-N-nitrosourea and by 7,12-dimethylbenz(a)anthracene, respectively, in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Estrogen Receptor Modulators; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen | 2001 |
Two-stage carcinogenesis in NMRI mice: intravaginal application of 7,12-dimethylbenz[a]anthracene as initiator followed by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate as promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Administration, Intravaginal; Animals; Carcinogens; Carcinoma; Cocarcinogenesis; Drug Synergism; Female; Hyperplasia; Leukemia, Experimental; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Models, Animal; Neoplasms, Experimental; Organ Specificity; Ovarian Neoplasms; Papilloma; Precancerous Conditions; Sarcoma, Experimental; Specific Pathogen-Free Organisms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Vagina; Vaginal Neoplasms | 1980 |
Preventive effect of indomethacin and melatonin on 7, 12-dimethybenz/a/anthracene-induced mammary carcinogenesis in female Sprague-Dawley rats. A preliminary report.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Female; Indomethacin; Mammary Neoplasms, Experimental; Melatonin; Rats; Rats, Sprague-Dawley | 2001 |
Cloning and characterization of a novel gene that is regulated by estrogen and is associated with mammary gland carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Base Sequence; Carcinogens; Cloning, Molecular; Endothelium, Vascular; Estradiol; Female; Fluorescent Antibody Technique; Gene Expression Regulation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Molecular Sequence Data; Neoplasm Proteins; Ovariectomy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Suppressor Proteins | 2001 |
Site-dependent modulating effects of conjugated fatty acids from safflower oil in a rat two-stage carcinogenesis model in female Sprague-Dawley rats.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Dietary Supplements; Dose-Response Relationship, Drug; Fatty Acids; Female; Glutathione Transferase; Hyperplasia; Linoleic Acid; Mammary Neoplasms, Experimental; Neoplasms; Nitrosamines; Organ Size; Phosphorylation; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Safflower Oil; Time Factors; Urinary Bladder Neoplasms | 2001 |
Acceleration of mammary neoplasia in aromatase transgenic mice by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aromatase; Carcinogenicity Tests; Disease Models, Animal; Female; Incidence; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Transgenic | 2001 |
Seaweed prevents breast cancer?
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Breast Neoplasms; Culture Media; Humans; Iodine; Mammary Neoplasms, Experimental; Rats; Seaweed; Solutions; Tumor Cells, Cultured | 2001 |
High susceptibility of transgenic rats carrying the human c-Ha-ras proto-oncogene to chemically-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Genetically Modified; Carcinogens; Cell Transformation, Neoplastic; Female; Genes, ras; Genetic Predisposition to Disease; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Mas; Rats | 2001 |
Inhibition by dietary dibenzoylmethane of mammary gland proliferation, formation of DMBA-DNA adducts in mammary glands, and mammary tumorigenesis in Sencar mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzoates; Carcinogens; Cell Division; Chalcones; Diet; DNA Adducts; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred SENCAR; Organ Size; Uterus | 2001 |
Bifidobacterium longum as a delivery system for gene therapy of chemically induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bifidobacterium; DNA Primers; Drug Delivery Systems; Female; Genetic Engineering; Genetic Therapy; Mammary Neoplasms, Experimental; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley | 2001 |
Induction of mammary epithelial cell differentiation and inhibition of dimethylbenz(A)anthracene-induced mammary tumour by co-administration of a pure antiestrogen ICI 182,780 and testosterone enanthate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Drug Therapy, Combination; Epithelial Cells; Estradiol; Female; Fulvestrant; Immunohistochemistry; Ki-67 Antigen; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Testosterone; Time Factors | 2001 |
Soluble low-molecular-mass tumor-associated proteins promote the suppression of mammary tumors by cyclophosphamide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Alkylating; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Humans; Mammary Neoplasms, Experimental; Molecular Weight; Neoplasm Proteins; Rats; Solubility; Time Factors; Treatment Outcome | 2001 |
Mechanistic studies on the inhibitory action of dietary dibenzoylmethane, a beta-diketone analogue of curcumin, on 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzoates; Binding, Competitive; Carcinogens; Cattle; Chalcones; Curcumin; Cytosol; Dietary Fats; DNA; DNA Adducts; DNA Damage; Drug Screening Assays, Antitumor; Estradiol; Female; Hypolipidemic Agents; Mammary Neoplasms, Experimental; Mice; Mice, Inbred SENCAR; Microsomes, Liver; Molecular Structure; Ovariectomy; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Spices; Triglycerides; Uterus | 2001 |
Reduced mammary gland carcinogenesis in transgenic mice expressing a growth hormone antagonist.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Birth Weight; Carcinogens; Disease Progression; Female; Growth Hormone; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Risk Factors | 2001 |
A virus (RMTDV) derived from chemically induced rat mammary tumors. I. Isolation and general characteristics.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Microscopy, Electron; Oncogenic Viruses; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Tumor Cells, Cultured | 1970 |
Do cocarcinogenic effects of ELF electromagnetic fields require repeated long-term interaction with carcinogens? Characteristics of positive studies using the DMBA breast cancer model in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Electromagnetic Fields; Female; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Species Specificity; Time Factors | 2001 |
Dietary genistein increased DMBA-induced mammary adenocarcinoma in wild-type, but not ER alpha KO, mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Caseins; Diet; Estradiol; Estrogen Receptor alpha; Female; Genistein; Insulin-Like Growth Factor I; Male; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Size; Ovary; Receptors, Estrogen; Skin Neoplasms; Uterus; Weight Gain | 2001 |
Effect of grape seed proanthocyanidins on colon aberrant crypts and breast tumors in a rat dual-organ tumor model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthocyanins; Azoxymethane; Carcinogens; Colonic Neoplasms; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Female; Glutathione Transferase; Liver; Mammary Neoplasms, Experimental; Ornithine Decarboxylase; Precancerous Conditions; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Seeds; Vitis | 2001 |
Soluble low-molecular-mass tumor-associated antigens promote the suppression of rat mammary tumors by tamoxifen and prevent its toxic effect.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Female; Mammary Neoplasms, Experimental; Molecular Weight; Rats; Rats, Wistar; Solubility; Survival Rate; Tamoxifen; Time Factors | 2002 |
Treatment of tamoxifen-refractory breast cancer--approach by animal models.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Cyclohexanes; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Mice; Mice, Nude; O-(Chloroacetylcarbamoyl)fumagillol; Picibanil; Prognosis; Rats; Receptors, Estrogen; Risk Assessment; Sesquiterpenes; Tamoxifen; Tegafur; Treatment Failure; Uracil | 2001 |
Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Southern; Breast Neoplasms; Carcinogens; Carcinoma in Situ; Carcinoma, Ductal, Breast; Chromosome Aberrations; DNA, Neoplasm; Estrogens; Female; Genes, myc; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Invasiveness; Ploidies; Rats; Rats, Inbred ACI; Rats, Sprague-Dawley; Testosterone | 2002 |
Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy of indole-3-carbinol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Carcinogens; Colonic Neoplasms; Disease Models, Animal; Female; Indoles; Liver; Liver Neoplasms; Mammary Neoplasms, Experimental; Mutagens; Neoplasms; Rats; Rats, Sprague-Dawley; Time Factors | 2002 |
Environmental carcinogens and p53 tumor-suppressor gene interactions in a transgenic mouse model for mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; BRCA2 Protein; Carcinogens, Environmental; Female; Genes, p53; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Knockout; Mice, Transgenic; Progesterone; Radiation Dosage | 2002 |
Deregulated expression of the PCPH proto-oncogene in rat mammary tumors induced with 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cricetinae; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Lactation; Mammary Neoplasms, Experimental; Mesocricetus; Oncogene Proteins; Organ Specificity; Proto-Oncogene Mas; Pyrophosphatases; Rats; Reference Values | 2002 |
Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Biflavonoids; Catechin; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Isoenzymes; Mammary Neoplasms, Experimental; Membrane Proteins; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Oxygen Consumption; Phenols; Plant Extracts; Proanthocyanidins; Prostaglandin-Endoperoxide Synthases; Resveratrol; Stilbenes; Vitis; Wine | 2001 |
Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer.
Topics: 17-Hydroxysteroid Dehydrogenases; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Cell Differentiation; Chemoprevention; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Onagraceae; Phytotherapy; Plant Extracts; Plant Oils; Tumor Cells, Cultured; Yeasts | 2002 |
[Anti-mutagenicity activity of dehydroepiandrosterone].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adjuvants, Immunologic; Animals; Antimutagenic Agents; Dehydroepiandrosterone; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Glucosephosphate Dehydrogenase; Mammary Neoplasms, Experimental; Mutagenicity Tests; Rats; Rats, Sprague-Dawley; Salmonella; Time Factors; Tumor Cells, Cultured | 2002 |
Constitutive telomerase expression promotes mammary carcinomas in aging mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Catalytic Domain; Cloning, Molecular; DNA-Binding Proteins; Female; Gene Expression; Kinetics; Mammary Neoplasms, Experimental; Mice; Mice, Knockout; Mice, Transgenic; Open Reading Frames; Telomerase; Telomere | 2002 |
Inducible nitric oxide synthase expression of tumor and stromal cells is associated with the progression of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Progression; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Neoplasm Invasiveness; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Reference Values; Stromal Cells | 2002 |
Lack of promotion of estrogen-dependent mammary gland tumors in vivo by an isopropanolic Cimicifuga racemosa extract.
Topics: 2-Propanol; 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Cell Division; Cimicifuga; Estrogens; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Plant Extracts; Prolactin; Ranunculaceae; Rats; Rats, Sprague-Dawley | 2002 |
The growth hormone-deficient Spontaneous Dwarf rat is resistant to chemically induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Cell Division; Crosses, Genetic; Disease Models, Animal; Dwarfism; Female; Growth Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley | 2002 |
The influence of the route of administration of 17beta-estradiol, intravenous (pulsed) versus oral, upon DMBA-induced mammary tumour development in ovariectomised rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Intranasal; Administration, Oral; Animals; Body Weight; Carcinogens; Dose-Response Relationship, Drug; Estradiol; Female; Infusions, Intravenous; Mammary Neoplasms, Experimental; Ovariectomy; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured; Uterus | 2002 |
Long-term effects of the mammary carcinogen 7,12-dimethylbenz(a) anthracene on hypothalamic gonadotropin-releasing hormone and its pituitary receptor gene expression, during the promotion stage, in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Gonadotropin-Releasing Hormone; Hypothalamus, Anterior; In Vitro Techniques; Mammary Neoplasms, Experimental; Pituitary Gland, Anterior; Proestrus; Rats; Rats, Sprague-Dawley; Receptors, LHRH; Ribonuclease, Pancreatic; RNA Probes; RNA, Messenger; Time Factors | 2002 |
Effect of selective ablation of proliferating mammary epithelial cells on MNU induced rat mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoviridae; Animals; Antiviral Agents; beta-Galactosidase; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Ganciclovir; Gene Expression Regulation, Developmental; Immunoenzyme Techniques; Incidence; Injections, Intralesional; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred WF; Thymidine Kinase | 2002 |
Chemopreventive effects of soy protein and purified soy isoflavones on DMBA-induced mammary tumors in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Diet; Female; Genistein; Glycine max; Isoflavones; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Soybean Proteins | 2001 |
Uptake and metabolism of hydroxymatairesinol in relation to its anticarcinogenicity in DMBA-induced rat mammary carcinoma model.
Topics: 4-Butyrolactone; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Anticarcinogenic Agents; Diet; Estrogens, Non-Steroidal; Female; Isoflavones; Lignans; Mammary Neoplasms, Experimental; Organ Size; Phytoestrogens; Plant Preparations; Rats; Rats, Sprague-Dawley; Uterus | 2001 |
Etiology-specific gene expression profiles in rat mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Imidazoles; Mammary Neoplasms, Experimental; Multigene Family; Oligonucleotide Array Sequence Analysis; Rats; Rats, Inbred F344; Rats, Sprague-Dawley | 2002 |
Cyclic nucleotides and their associated enzymes in 9,10-dimethyl-1,2-benzanthracene-induced mammary tumors of rats.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 9,10-Dimethyl-1,2-benzanthracene; Adenylyl Cyclases; Animals; Benz(a)Anthracenes; Cyclic AMP; Cyclic GMP; Female; Guanylate Cyclase; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Pregnancy; Rats | 1978 |
Steroid metabolism in normal mammary gland and in the dimethylbenzanthracene-induced mammary tumor of rats.
Topics: 20-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cytosol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; NAD; NADP; Progesterone; Rats; Testosterone | 1978 |
Analysis of mammary tumors for cytochemical evidence of endogenous mammary peroxidase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Female; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Peroxidases; Pregnancy; Rats | 1979 |
[Distribution of bleomycin in sesame oil suspension in organs of rat with mammary carcinoma induced by 7,12-dimethylbenz (a) anthracene and its effect on the tumors (author's transl)].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bleomycin; Female; Lung; Mammary Neoplasms, Experimental; Rats; Sesame Oil; Suspensions | 1975 |
Quantitation of casein messenger ribonucleic acid sequences using a specific complementary DNA hybridization probe.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Avian Myeloblastosis Virus; Base Sequence; Caseins; DNA; Female; Kinetics; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Nucleic Acid Hybridization; Pregnancy; Rats; RNA-Directed DNA Polymerase; RNA, Messenger; Temperature; Templates, Genetic | 1976 |
Stimulation in rat DMBA-mammary tumours of the synthesis of a protein similar to the oestrogen-induced protein of the rat uterus [proceedings].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Neoplasm Proteins; Protein Biosynthesis; Rats; Receptors, Estrogen; Uterus | 1976 |
[Joint use of thyroid and antithyroid preparations].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antithyroid Agents; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Female; Mammary Neoplasms, Experimental; Rats; Thyroxine; Time Factors | 1979 |
Antitumour effect of cyclofenil (F6066) on DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cresols; Cyclofenil; Estrus; Female; Mammary Neoplasms, Experimental; Pregnancy; Rats; Receptors, Estrogen | 1978 |
Effect of fetal tissue on experimental (7,12-dimethylbenz[a]anthracene) breast cancer in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Fetus; Liver; Mammary Neoplasms, Experimental; Rats | 1978 |
[Changes in biogenic amines and connective tissue in the process of chemical carcinogenesis].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biogenic Amines; Carcinogens; Connective Tissue; Female; Mammary Neoplasms, Experimental; Methylcholanthrene; Neoplasms, Experimental; Rats; Sarcoma, Experimental | 1978 |
Effect of oophorectomy on estrogen receptors in rat mammary tumors induced by 7,12-dimethylbenz (a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen | 1977 |
Characterization of androgen receptors in 7,12-dimethylbenz(a)-anthracene-induced and transplantable rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Binding, Competitive; Cytosol; Diethylstilbestrol; Dihydrotestosterone; Estradiol; Female; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Rats; Rats, Inbred WF; Receptors, Androgen; Receptors, Steroid; Testosterone; Transplantation, Isogeneic | 1978 |
Binding of 7,12-dimethylbenz[a]anthracene to BALB/c mouse mammary gland DNA in organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aldosterone; Animals; Benz(a)Anthracenes; DNA; Female; Hydrocortisone; Insulin; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Precancerous Conditions; Prolactin | 1978 |
Restraint-induced inhibition of 7,12-dimethylbenz[a]anthracene-induced mammary tumors: relation to stages of tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Cell Division; Cell Survival; Female; Mammary Neoplasms, Experimental; Rats; Restraint, Physical; Time Factors | 1978 |
Neoplastic transformation of rat mammary cells exposed to 7,12-dimethylbenz[alpha]anthracene or N-nitrosomethylurea in cell culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Cells, Cultured; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats | 1978 |
The effect of altered thyroid state on prolactin binding to liver and 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Hyperthyroidism; Hypothyroidism; Liver; Mammary Neoplasms, Experimental; Prolactin; Propylthiouracil; Rats; Thyroid Gland; Thyroxine | 1978 |
[Induction of mammary gland cancer in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Benz(a)Anthracenes; Disease Models, Animal; Female; Humans; Mammary Neoplasms, Experimental; Placental Hormones; Rats | 1978 |
Androgen effects mediated by estrogen receptor in 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Binding Sites; Cell Nucleus; Cytosol; Dihydrotestosterone; Estradiol; Female; Leucine; Mammary Neoplasms, Experimental; Neoplasm Proteins; Rats; Receptors, Estrogen | 1978 |
Regulatory interrelationships for insulin and estrogen action in mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Amino Acids; Animals; Carbohydrate Metabolism; Castration; Diabetes Mellitus, Experimental; Estradiol; Female; Insulin; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Receptor, Insulin; Receptors, Estrogen | 1978 |
Isolation and purification of rat mammary tumor peroxidase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcium Chloride; Chromatography, Affinity; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Peroxidases; Rats; Receptors, Estrogen; Solubility | 1978 |
Unsaturated fatty acid requirements for growth and survival of a rat mammary tumor cell line.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cell Line; Cell Survival; Culture Media; Fatty Acids, Unsaturated; Female; Linoleic Acids; Mammary Neoplasms, Experimental; Microscopy, Electron; Rats | 1978 |
Vasopressin stimulation of acetate incorporation into lipids in a dimethylbenz(a)anthracene-induced rat mammary tumor cell line.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetates; Animals; Benz(a)Anthracenes; Cell Line; Growth Hormone; Insulin; Lipids; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Oxytocin; Prolactin; Rats; Vasopressins | 1978 |
[Early effect of estradiol on ultrastructure of chromatin in the endometrium and hormone-dependent mammary tumors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Chromatin; Dihydrotestosterone; Endometrium; Estradiol; Female; Heterochromatin; In Vitro Techniques; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Progesterone; Rats; Receptors, Estrogen; Sheep; Tamoxifen; Time Factors | 1978 |
Effect of chemical carcinogen treatment on the immunogenicity of mouse mammary tumors arising from hyperplastic alveolar nodule outgrowth lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Benz(a)Anthracenes; Cytotoxicity Tests, Immunologic; Female; Graft Rejection; Immunity; In Vitro Techniques; Mammary Neoplasms, Experimental; Methylcholanthrene; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Precancerous Conditions; Transplantation, Isogeneic | 1978 |
Is there any association between the pharmacologic control of prolactin release and its action on mammary carcinogenesis in the rat?
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carbon Tetrachloride; Coumarins; Female; Mammary Neoplasms, Experimental; Phenobarbital; Prolactin; Rats | 1977 |
Arachidonic acid distribution in lipids of mammary glands and DMBA-induced tumors of rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonic Acids; Fatty Acids; Female; Gestational Age; Lipid Metabolism; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Phospholipids; Pregnancy; Rats | 1978 |
A proposed selective cell carcinogenesis in mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Histological Techniques; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Microscopy, Electron; Rats | 1978 |
Acquisition of angiogenic capacity and neoplastic transformation in the rat mammary gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Pregnancy; Rats; Rats, Inbred BN; Rats, Inbred F344 | 1978 |
[Measurement of estrogen receptor in relation to the prediction of hormone dependency in 7,12-dimethylbenz(a)anthracene-induced rat breast cancer and in human breast cancer (author's transl)].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Castration; Female; Humans; Mammary Neoplasms, Experimental; Prognosis; Rats; Receptors, Estrogen | 1978 |
Developmental stage of the rat mammary gland as determinant of its susceptibility to 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Age Factors; Animals; Benz(a)Anthracenes; Female; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Precancerous Conditions; Pregnancy; Rats | 1978 |
DNA labeling index and structure of the rat mammary gland as determinants of its susceptibility to carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; DNA; Female; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Parity; Pregnancy; Rats | 1978 |
Lactate dehydrogenase in normal mammary glands and in 7,12-dimethylbenz[a]anthracene-induced mammary tumors in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Female; Isoenzymes; L-Lactate Dehydrogenase; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Ovary; Pregnancy; Rats | 1979 |
Serum haptoglobin levels in mice with 7, 12-dimethylbenz[a]anthracene-induced tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Haptoglobins; Lymphoma, Non-Hodgkin; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Sarcoma, Experimental; Time Factors | 1978 |
Effect of neonatal administration of sex steroids on 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma and dysplasia in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Benz(a)Anthracenes; Corpus Luteum; Dihydrotestosterone; Estradiol; Female; Gonadal Steroid Hormones; Mammary Neoplasms, Experimental; Progesterone; Rats; Testosterone | 1978 |
Pilot study on the growth inhibition by estramustine phosphate (Estracyt) of rat mammary tumours sensitive and insensitive of oestrogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Estramustine; Estrogens; Female; Mammary Neoplasms, Experimental; Nitrogen Mustard Compounds; Pilot Projects; Rats | 1979 |
Serial transplantation of chemical carcinogen-induced mouse mammary ductal dysplasias.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Ovary; Precancerous Conditions; Time Factors; Transplantation, Isogeneic; Urethane | 1979 |
[Blastomogenesis in repeated administration of DMBA in rats during different life periods].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Benz(a)Anthracenes; Brain Neoplasms; Carcinogens; Female; Fetus; Injections; Kidney Neoplasms; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Placenta; Pregnancy; Rats; Spinal Cord Neoplasms; Time Factors | 1978 |
Synthesis of steroidal nitrosoureas with antitumor activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antineoplastic Agents; Estradiol; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Nitrosourea Compounds; Rats; Rats, Inbred F344 | 1979 |
Estradiol and progesterone receptor activities in stored lyophilised target tissue.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cattle; Drug Stability; Estradiol; Female; Freeze Drying; Humans; Kinetics; Mammary Neoplasms, Experimental; Promegestone; Rats; Receptors, Progesterone; Time Factors; Uterus | 1978 |
Effects of estradiol and prolactin on steroid receptor levels in 7,12-dimethylbenz(a)anthracene-induced mammary tumors and uterus in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Estradiol; Female; Hypophysectomy; Mammary Neoplasms, Experimental; Prolactin; Promegestone; Rats; Receptors, Estrogen; Receptors, Progesterone; Uterus | 1978 |
Dietary polyunsaturated fat versus saturated fat in relation to mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Fatty Acids, Unsaturated; Female; Humans; Mammary Neoplasms, Experimental; Oils; Rats | 1979 |
[Proton hypophysectomy and the induction of mammary cancer].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Pituitary Gland; Pituitary Irradiation; Protons; Rats; Time Factors | 1979 |
[Role of vitamin A in chemical carcinogenesis in the mammary gland].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Female; Liver; Mammary Neoplasms, Experimental; Rats; Time Factors; Vitamin A | 1979 |
Inhibition of chemical carcinogen-induced neoplasia by coumarins and alpha-angelicalactone.
Topics: 4-Butyrolactone; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Coumarins; Female; Furans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Rats; Stomach Neoplasms; Structure-Activity Relationship | 1979 |
Relationship between amount and type of dietary fat in promotion of mammary carcinogenesis induced by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Breast Neoplasms; Cocarcinogenesis; Dietary Fats; Female; Humans; Linoleic Acids; Mammary Neoplasms, Experimental; Rats | 1979 |
Induction of pituitary and mammary tumors in male, "fale" and female rats by either DMBA, estradiol implant or combined treatment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Drug Implants; Estradiol; Estrogens; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Mammary Neoplasms, Experimental; Pituitary Neoplasms; Prolactin; Rats; Sex Factors | 1979 |
Effects of LS 1727, a nitrosocarbamate of 19-nortestosterone, on dimethylbenz (a)anthracene-induced mammary tumors in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Female; Hormones; Lomustine; Mammary Neoplasms, Experimental; Nandrolone; Rats; Tissue Distribution | 1979 |
[The behavior of 7, 12-dimethylbenz(a)anthracene (DMBA)-induced mammary tumors in rats during pregnancy and lactation and hormone levels in the pituitary and plasma (author's transl)].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Follicle Stimulating Hormone; Lactation; Luteinizing Hormone; Mammary Neoplasms, Experimental; Pituitary Gland; Pregnancy; Pregnancy Complications; Progesterone; Prolactin; Rats | 1979 |
Inhibition of 7,12-dimethylbenz[alpha]anthracene-induced mammary tumorigenesis in rats by a synthetic protease inhibitor, N,N-dimethylamino-(p-(p'-guanidinobenzoyloxy)) benzilcarbonyloxyglycolate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Benz(a)Anthracenes; Female; Glycolates; Guanidines; Mammary Neoplasms, Experimental; Protease Inhibitors; Rats | 1978 |
Age as a modifying factor of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in the lewis rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Benz(a)Anthracenes; Female; Mammary Neoplasms, Experimental; Neoplasm Regression, Spontaneous; Rats | 1979 |
Fat droplet formation in rat lactating mammary gland and mammary carcinomas viewed by freeze-fracture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Endoplasmic Reticulum; Female; Freeze Fracturing; Golgi Apparatus; Intracellular Membranes; Lactation; Lipids; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Membrane Lipids; Methylnitrosourea; Pregnancy; Rats | 1979 |
Opiate antagonists can inhibit mammary tumor growth in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Endorphins; Female; Mammary Neoplasms, Experimental; Naloxone; Naltrexone; Rats | 1979 |
The effect of hydroxylamine on the morphology of the rat mammary gland and on the induction of mammary tumors by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Atrophy; Epithelium; Female; Hydroxylamines; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats | 1979 |
Hormonal regulation in two rat mammary cancer cell lines: glucocorticoid and androgen receptors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cell Line; Cytosol; Dexamethasone; Dihydrotestosterone; Estradiol; Estrenes; Female; Hydrocortisone; Mammary Neoplasms, Experimental; Methylnitrosourea; Progesterone; Rats; Receptors, Androgen; Receptors, Glucocorticoid; Receptors, Steroid; Testosterone Congeners | 1979 |
Estradiol binding to nuclear receptors in human breast cancer tissue (MCF-7 cell line) and in dimethylbenz(a)anthracene-induced mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Line; Cell Nucleus; Cytoplasm; Estradiol; Female; Humans; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Rats; Receptors, Estrogen; Temperature; Time Factors | 1979 |
Aromatase inhibitors--IV. Regression of hormone-dependent, mammary tumors in the rat with 4-acetoxy-4-androstene-3,17-dione.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Aromatase Inhibitors; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Oxidoreductases; Progesterone; Prolactin; Rats; Testosterone | 1979 |
Steroid delta 4-5 beta-reductase in human mammary tumors.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Breast Neoplasms; Dihydrotestosterone; Etiocholanolone; Female; History, 18th Century; Humans; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Stereoisomerism; Testosterone | 1979 |
Control of experimental breast cancer by antioestrogenic therapies [proceedings].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Female; Mammary Neoplasms, Experimental; Ovary; Rats; Tamoxifen | 1979 |
Collagen synthesis in capsules surrounding dimethylbenzanthracene-induced rat breast tumors and the effect of pretreatment with beta-aminopropionitrile.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminopropionitrile; Animals; Benz(a)Anthracenes; Collagen; Female; Lathyrism; Mammary Neoplasms, Experimental; Neoplasm Metastasis; Rats | 1979 |
Synthesis of DNA and lecithin in tissue culture and oestrogen receptor activity in rat mammary tumours dependent on and independent of the ovary.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Culture Techniques; DNA, Neoplasm; Female; Hormones; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Ovary; Phosphatidylcholines; Rats; Receptors, Estrogen; Transplantation, Homologous | 1979 |
Purification of the cytoplasmic oestrogen receptor from mammary tumours induced in rats with dimethylbenzanthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromatography, Affinity; Chromatography, Gel; Cytoplasm; Estradiol; Female; Isoelectric Focusing; Mammary Neoplasms, Experimental; Molecular Weight; Rats; Receptors, Estrogen | 1979 |
Incidence and growth of mammary tumors induced by 7,12-dimethylbenz[a]anthracene as related to the dietary content of fat and antioxidant.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Butylated Hydroxytoluene; Cocarcinogenesis; Cresols; Dietary Fats; Fats, Unsaturated; Female; In Vitro Techniques; Mammary Neoplasms, Experimental; Microsomes, Liver; Mutagens; Rats | 1979 |
Susceptibility of the mammary gland to carcinogenesis: I Differentiation of the mammary gland as determinant of tumor incidence and type of lesion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Age Factors; Animals; Cell Differentiation; DNA; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats | 1979 |
Effects of progesterone on mammary carcinogenesis by DMBA applied directly to rat mammae.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Administration, Topical; Animals; Benz(a)Anthracenes; Female; Injections, Subcutaneous; Mammary Neoplasms, Experimental; Mice; Progesterone | 1979 |
Modification of the effect of a gonadoliberin analog on 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors by hormone replacement.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Gonadotropin-Releasing Hormone; Hormones; Mammary Neoplasms, Experimental; Ovary; Perphenazine; Prolactin; Rats | 1979 |
Apparent rat strain-related sensitivity to phorbol promotion of mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Drug Synergism; Female; Leukemia, Experimental; Leukemia, Lymphoid; Mammary Neoplasms, Experimental; Neoplasms, Multiple Primary; Neoplasms, Radiation-Induced; Phorbols; Procarbazine; Rats; Rats, Inbred Strains; Species Specificity; X-Rays | 1979 |
[Study of the tropism of sodium Selenium-75-selenite to experimental cancer of the mammary gland].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Female; Kinetics; Mammary Neoplasms, Experimental; Radioisotopes; Rats; Selenium | 1979 |
Occurrence of steroidal allyl alcohols in normal mammary tissues in vitro, in relation to experimental mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenediols; Animals; Castration; Estradiol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Pregnenes; Progesterone; Rats; Species Specificity; Testosterone | 1979 |
Effects of transplacental exposure to diethylstilbestrol on carcinogenic susceptibility during postnatal life in hamster progeny.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Cricetinae; Diethylstilbestrol; Female; Genital Neoplasms, Female; Male; Mammary Neoplasms, Experimental; Maternal-Fetal Exchange; Melanoma; Mesocricetus; Neoplasms, Experimental; Pregnancy; Skin Neoplasms; Stomach Neoplasms | 1979 |
Effect of catechol estrogens on rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Estriol; Estrone; Female; Hydroxyestrones; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred F344 | 1979 |
Inhibition of mammary tumorigenesis in carcinogen-treated Lewis rats by suppression of prolactin secretion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Precancerous Conditions; Prolactin; Rats; Time Factors | 1979 |
Effective tumor immunization induced by cells of elevated membrane-lipid microviscosity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; B-Lymphocytes; Female; Lymphoma; Mammary Neoplasms, Experimental; Membrane Fluidity; Membrane Lipids; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; T-Lymphocytes; Transplantation, Isogeneic | 1979 |
Inhibition of mammary carcinogenesis of dimethylbenzanthracene treated rats with a brominated triphenylethylene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Adrenal Cortex; Animals; Benz(a)Anthracenes; Corpus Luteum; Estradiol Congeners; Female; Mammary Neoplasms, Experimental; Necrosis; Organ Size; Ovary; Rats; Stilbenes | 1979 |
Sialic acid metabolism in rats undergoing chemically-induced mammary gland carcinogenesis in specific dietary states.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Dietary Fats; Female; Liver; Mammary Neoplasms, Experimental; N-Acylneuraminate Cytidylyltransferase; Neuraminidase; Rats; Sialic Acids; Sialyltransferases | 1979 |
Study of the anti-tumor effect of polypeptide pineal extract.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cattle; Female; Leukemia, Experimental; Liver Neoplasms, Experimental; Mammary Neoplasms, Experimental; Melanoma; Mice; Peptides; Pineal Gland; Rats; Uterine Cervical Neoplasms | 1979 |
The methanol extraction residue of Bacillus Calmette-Guerin protects against 7,12-dimethylbenz(alpha)anthracene-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Dietary Fats; Female; Immunotherapy; Mammary Neoplasms, Experimental; Mycobacterium bovis; Rats | 1979 |
Hormone dependency of rat mammary carcinoma--a comparison of two assay systems.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Ovary; Prolactin; Rats; Receptors, Estrogen; Receptors, Progesterone; Succinate Dehydrogenase | 1979 |
Neoplastic transformation of epithelial cells in whole mammary gland in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Culture Media; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Organ Culture Techniques | 1979 |
Retinoid prevents mammary gland transformation by carcinogenic hydrocarbon in whole-organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Retinoids; Vitamin A | 1979 |
Peroxidase as a marker enzyme in estrogen-responsive tissues.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Cell Nucleus; Enzyme Induction; Estradiol; Estrogens; Female; Mammary Neoplasms, Experimental; Peroxidases; Progesterone; Rats; Receptors, Estrogen; Uterus | 1978 |
Mammary tumorigenesis in the rat following prenatal exposure to diethylstilbestrol and postnatal treatment with 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Diethylstilbestrol; Female; Mammary Neoplasms, Experimental; Maternal-Fetal Exchange; Pregnancy; Rats; Time Factors | 1979 |
[Chloramphenicol and dextramycin, inhibitors of mammary carcinogenesis induced by 7,12-dimethylbenz(a)anthracene].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chloramphenicol; Female; Mammary Neoplasms, Experimental; Rats; Stereoisomerism | 1979 |
Normalization of anti-radical activity of lipids by retinyl acetate in mammary gland tumorigenesis induced by 7, 12-dimethylbenz (a) anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Free Radicals; Lipid Metabolism; Mammary Neoplasms, Experimental; Rats; Vitamin A | 1979 |
Prolactin binding to dissociated cells from rat mammary tumors and mammary gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding, Competitive; Cell Line; Female; Kinetics; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Pregnancy; Prolactin; Protein Binding; Rats | 1979 |
Elevated collagen synthesis in dimethylbenz(a)-anthracene rat breast tumors and the effect of beta-amino propionitrile on tumor growth.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminopropionitrile; Animals; Collagen; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1978 |
Anti-tumour efficacy of calusterone against DMBA-induced rat mammary adenocarcinoma in vivo and in organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Castration; DNA, Neoplasm; Estradiol; Female; Mammary Neoplasms, Experimental; Methyltestosterone; Organ Culture Techniques; Rats; Rats, Inbred Lew; RNA, Neoplasm; Testosterone | 1976 |
Influence of hormonal alteration of host on estrogen-binding capacity in 7,12-dimethylbenz(a)anthracene-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetonitriles; Animals; Castration; Diabetes Mellitus; Ergolines; Estradiol; Estrogens; Female; Insulin; Mammary Neoplasms, Experimental; Prolactin; Rats; Streptozocin; Time Factors | 1976 |
The role of myoepithelial cells in the morphogenesis of induced mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinosarcoma; Female; Mammary Neoplasms, Experimental; Microscopy, Electron; Rats | 1979 |
Hormone dependence and estradiol receptors in the D series of mammary nodule outgrowth lines and tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Adrenalectomy; Animals; Castration; Cell Line; Cytoplasm; Estradiol; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Precancerous Conditions; Receptors, Cell Surface; Time Factors; Transplantation, Homologous | 1975 |
On the mechanism of prolactin and estrogen action in 7,12 dimethylbenz(A)anthracene-induced mammary carcinoma in the rat. II. In vivo tumor responses and estrogen receptor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Estrogens; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Receptors, Cell Surface | 1975 |
Neoplasms in strains of splenectomized mice after a single 7,12-dimethylbenz[alpha]anthracene treatment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Adrenal Gland Neoplasms; Amyloidosis; Animals; Benz(a)Anthracenes; Carcinoma, Hepatocellular; Colonic Neoplasms; Female; Hemangioma; Leukemia, Experimental; Liver Neoplasms; Lung Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Ovarian Neoplasms; Skin Neoplasms; Spleen; Splenectomy; Stomach Neoplasms | 1975 |
Macrophage migration inhibition and lymphocyte stimulation with mammary tumor virus associated antigens in Balb/c mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Antigens, Viral; Cell Migration Inhibition; Female; Lymphocyte Activation; Macrophages; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Spleen | 1976 |
Tamoxifen as an anti-tumour agent: effect on oestrogen binding.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Receptors, Cell Surface; Stilbenes; Tamoxifen; Uterus; Vagina | 1976 |
Proceedings: Specificity of steroid binding by the oestrogen receptor of rat mammary tumours induced by 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Receptors, Cell Surface | 1976 |
Relationship of adenosine 3',5'-cyclic monophosphate and guanosine 3',5'-cyclic monophosphate to growth of dimethylbenz(a)anthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Cyclic AMP; Cyclic GMP; Cyclophosphamide; Estrogens; Female; Insulin; Mammary Neoplasms, Experimental; Ovary; Prolactin; Rats | 1976 |
Estrogen and prolactin receptor concentrations in rat mammary tumors and response to endocrine ablation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Estrogens; Female; Hypophysectomy; Mammary Neoplasms, Experimental; Prolactin; Rats; Receptors, Cell Surface | 1976 |
Regulation of estrogen receptors in ovarian-dependent rat mammary tumors. I. Effects of castration and prolactin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Castration; Cell Nucleus; Cytosol; Estradiol; Estrogens; Female; Mammary Neoplasms, Experimental; Ovary; Prolactin; Rats; Receptors, Cell Surface | 1976 |
Specific progesterone receptors in dimethylbenzanthracene (DMBA)-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Binding, Competitive; Cytosol; Dexamethasone; Estradiol; Female; Hydrocortisone; Kinetics; Mammary Neoplasms, Experimental; Progesterone; Protein Binding; Rats; Receptors, Cell Surface | 1976 |
Cell cycle-related hormone carcinogen interaction during chemical carcinogen induction of nodule-like mammary lesions in organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aldosterone; Animals; Carcinogens; Cell Division; Cell Survival; DNA, Neoplasm; Drug Interactions; Female; Hormones; Hydrocortisone; Insulin; Mammary Neoplasms, Experimental; Methylcholanthrene; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Precancerous Conditions; Prolactin; Receptors, Cell Surface | 1976 |
Characteristics of progesterone-binding components in neoplastic mammary tissues of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Aldosterone; Androgens; Animals; Binding, Competitive; Corticosterone; Cytosol; Estrogens; Female; Hydrocortisone; In Vitro Techniques; Kinetics; Ligands; Mammary Neoplasms, Experimental; Progesterone; Rats; Receptors, Cell Surface; Triamcinolone Acetonide | 1976 |
Lack of correlation between the presence of estrogen receptor and histological type of mammary cancer induced by 7,12-dimethylbenz[alpha]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Estrogens; Female; Mammary Neoplasms, Experimental; Rats; Receptors, Cell Surface | 1975 |
Preneoplastic lesions in murine mammary cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; Female; Hyperplasia; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Precancerous Conditions; Urethane | 1976 |
Prolactin receptors in 7,12-dimethylbenz(a) anthracene-induced mammary tumors following endocrine ablation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Depression, Chemical; Female; Hypophysectomy; Liver; Mammary Neoplasms, Experimental; Prolactin; Rats; Receptors, Cell Surface | 1976 |
Prolactin receptors and androgen-induced regression of 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Receptors, Cell Surface; Testosterone | 1976 |
High inhibitory activity of a new antiestrogen, RU 16117 (11alpha-methoxy ethinyl estradiol), on the development of dimethylbenz(a)anthracene-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Estradiol; Estrogen Antagonists; Ethinyl Estradiol; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Ovary; Prolactin; Rats; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Progesterone | 1977 |
Mammary tumorigenesis in chemical carcinogen-treated mice. VI. Tumor-producing capabilities of mammary dysplasias in BALB/cCrgl mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cell Line; Disease Models, Animal; Female; Hyperplasia; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Ovary; Pituitary Gland; Precancerous Conditions; Transplantation, Isogeneic | 1976 |
Predominant role of prolactin in stimulating the growth of 7, 12-dimethylbenz(a)anthracene-induced rat mammary tumor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetonitriles; Animals; Benz(a)Anthracenes; Drug Administration Schedule; Ergolines; Estrogens; Female; Mammary Neoplasms, Experimental; Ovary; Perphenazine; Prolactin; Rats; Receptors, Cell Surface; Receptors, Estrogen; Tamoxifen | 1977 |
Autoradiographic localization of prolactin receptors in 7,12-dimethylbnez[a]anthracene-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Autoradiography; Benz(a)Anthracenes; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Receptors, Cell Surface | 1977 |
Estrogen receptors in androgen-induced breast tumor regression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Cytoplasm; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Receptors, Cell Surface; Receptors, Estrogen; Remission, Spontaneous; Testosterone | 1977 |
Effect of high-oleic and high-linoleic safflower oils on mammary tumors induced in rats by 7,12-dimethylbenz(alpha)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Body Weight; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Papillary; Cocarcinogenesis; Cocos; Dietary Fats; Drug Synergism; Female; Linoleic Acids; Mammary Neoplasms, Experimental; Oils; Oleic Acids; Phytosterols; Rats; Safflower Oil; Vitamin E | 1977 |
Control of hormone receptor levels and growth of 7,12-dimethylbenz(a)anthracene-induced mammary tumors by estrogens, progesterone and prolactin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Estradiol; Female; Mammary Neoplasms, Experimental; Norpregnadienes; Progesterone; Progesterone Congeners; Protein Binding; Rats; Receptors, Cell Surface | 1977 |
Considerations on the preneoplastic lesions of the mammary gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast; Breast Neoplasms; Bromocriptine; Cell Transformation, Neoplastic; Cells, Cultured; Ergolines; Female; Humans; Hyperplasia; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Neoplasm Transplantation; Precancerous Conditions; Transplantation, Heterologous; Urethane | 1977 |
Influence of altered lysosomal enzyme activities on the regression of DMBA-induced rat mammary tumours.
Topics: 4-Nitrophenylphosphatase; 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Cycloheximide; Enzyme Activation; Female; Glucosephosphate Dehydrogenase; Glucuronidase; Lysosomes; Mammary Neoplasms, Experimental; Phosphogluconate Dehydrogenase; Rats | 1977 |
Distribution of 18F-5-fluorouracil in tumor-bearing mice and rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Fluorine; Fluorouracil; Leukemia, Experimental; Liver Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Radioisotopes; Rats; Rats, Inbred BUF; Rats, Inbred F344; Sarcoma, Experimental; Tissue Distribution | 1978 |
Protection against 7, 12-dimethylbenz[a]anthracene-induced rat mammary carcinoma by infection with mouse xenotropic type C virus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Viral; Antigens, Viral; Benz(a)Anthracenes; Female; Immunity; In Vitro Techniques; Lymphocyte Activation; Mammary Neoplasms, Experimental; Rats; Retroviridae; Time Factors; Tumor Virus Infections | 1978 |
Antagonistic action between cyclic AMP and estrogen in phosphorylation of mammary tumor nuclear proteins.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cyclic AMP; Estradiol; Female; In Vitro Techniques; Mammary Neoplasms, Experimental; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nucleoproteins; Phosphorylation; Rats; Remission, Spontaneous | 1978 |
Nuclear protein phosphorylation and hormone-dependent mammary tumor regression following dibutyryl cyclic adenosine 3':5'-monophosphate treatment or ovariectomy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bucladesine; Castration; Female; Histones; Mammary Neoplasms, Experimental; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nucleoproteins; Phosphorylation; Protein Kinases; Rats; Remission, Spontaneous | 1978 |
Inverse relation between estrogen receptors and cyclic adenosine 3':5'-monophosphate-binding proteins in hormone-dependent mammary tumor regression due to dibutyryl cyclic adenosine 3':5'-monophosphate treatment or ovariectomy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bucladesine; Castration; Cell Nucleus; Cyclic AMP; Cytoplasm; Female; Mammary Neoplasms, Experimental; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Protein Kinases; Rats; Receptors, Cyclic AMP; Receptors, Estrogen; Remission, Spontaneous | 1978 |
Expression of RNA of an endogenous replication-defective retrovirus in rat mammary adenocarcinomas induced by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Cell Line; Defective Viruses; Female; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Nucleic Acid Hybridization; Rats; Retroviridae; RNA, Viral; Uterine Neoplasms; Virus Replication | 1978 |
Chemical carcinogenesis in C3H/StWi mice, a worthwhile experimental model for breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Diethylstilbestrol; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C3H; Retroviridae; RNA, Viral | 1978 |
Increase of cyclic AMP-dependent protein kinase type II as an early event in hormone-dependent mammary tumor regression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cyclic AMP; Enzyme Activation; Estradiol; Female; Mammary Neoplasms, Experimental; Neoplasm Regression, Spontaneous; Phosphorylation; Protamine Kinase; Protein Kinases; Rats | 1978 |
Murine mammary tumor virus expression during mammary tumorigenesis in BALB/c mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Cell Transformation, Neoplastic; Hormones; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Nucleic Acid Hybridization; RNA, Viral | 1979 |
Dibutyryl cyclic-AMP mimics the effect of ovariectomy on a dehydrogenase in hormone-dependent mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bucladesine; Castration; Female; Glucosephosphate Dehydrogenase; Isoenzymes; Mammary Neoplasms, Experimental; Microsomes; Neoplasms, Hormone-Dependent; Ovary; Rats | 1979 |
Paramagnetic changes during development of DMBA-induced mammary tumours in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Benz(a)Anthracenes; Carcinoma; Carcinoma, Papillary; Ceruloplasmin; Electron Spin Resonance Spectroscopy; Female; Free Radicals; Mammary Neoplasms, Experimental; Rats | 1979 |
Prolactin receptors in primary cultures of carcinogen-induced rat-mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cells, Cultured; Cytosol; Estradiol; Female; Hyaluronoglucosaminidase; Mammary Neoplasms, Experimental; Microbial Collagenase; Placental Lactogen; Prolactin; Promegestone; Rats; Receptors, Cell Surface | 1979 |
Paramagnetic changes in cancer: DMBA-induced tumours studied in non-lyophilized and lyophilized tissues.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Electron Spin Resonance Spectroscopy; Female; Free Radicals; Freeze Drying; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Manganese; Rats | 1979 |
Cyclic AMP receptor triggers nuclear protein phosphorylation in a hormone-dependent mammary tumor cell-free system.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Cell-Free System; Chromosomal Proteins, Non-Histone; Cyclic AMP; Female; Mammary Neoplasms, Experimental; Neoplasm Proteins; Phosphorylation; Protein Kinases; Rats; Receptors, Cyclic AMP | 1979 |
Antiestrogen modulation of the growth and properties of ovarian-autonomous and ovarian-dependent mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Ovary; Rats; Rats, Inbred F344; Receptors, Cell Surface | 1979 |
Mouse mammary tumor virus genome expression in chemical carcinogen-induced mammary tumors in low- and high-tumor-incidence mouse strains.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Genes, Viral; Kinetics; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred Strains; Nucleic Acid Hybridization; RNA, Viral; Species Specificity | 1979 |
Effects of progesterone and R2323 on the development of dimethylbenzanthracene-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Dose-Response Relationship, Drug; Estradiol; Female; Gestrinone; Mammary Neoplasms, Experimental; Norpregnatrienes; Progesterone; Prolactin; Promegestone; Rats; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Progesterone | 1979 |
Comparison of glucocorticoid-binding proteins in normal and neoplastic mammary tissues of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding, Competitive; Buffers; Cell Nucleus; Cytosol; Female; Hydrogen-Ion Concentration; Kinetics; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Molecular Weight; Neoplasm Proteins; Pregnancy; Proteins; Rats; Receptors, Cell Surface; Structure-Activity Relationship; Sulfhydryl Reagents; Time Factors; Triamcinolone Acetonide | 1975 |
Stimulation of growth of carcinogen-induced mammary cancers in rats by thyrotropin-releasing hormone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Stimulation, Chemical; Thyroidectomy; Thyrotropin-Releasing Hormone | 1977 |
Inhibition of mammary cancer by retinyl methyl ether.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenofibroma; Animals; Benz(a)Anthracenes; Drug Administration Schedule; Female; Mammary Neoplasms, Experimental; Neoplasm Proteins; Rats; Retinol-Binding Proteins; Vitamin A | 1977 |
Inhibition of carcinogenic effects of polycyclic hydrocarbons by benzyl isothiocyanate and related compounds.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Benz(a)Anthracenes; Benzopyrenes; Diet; Drug Administration Schedule; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Rats; Stomach Neoplasms; Thiocyanates | 1977 |
In vitro effects of prolactin and hydrocortisone on 7,12-DMBA-induced mammary tumour and virus-induced sarcoma in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; DNA, Neoplasm; Female; Hydrocortisone; Mammary Neoplasms, Experimental; Prolactin; Rats; Sarcoma, Experimental | 1977 |
Hyperplastic alveolar nodules of the rat mammary gland: tumor-producing capability in vivo and in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Organ Culture Techniques; Precancerous Conditions; Pregnancy; Rats; Rats, Inbred Strains; Transplantation, Isogeneic | 1977 |
Potent inhibitory effect of a new antiestrogen (RU 16117) on the growth of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estrogen Antagonists; Ethinyl Estradiol; Female; Mammary Neoplasms, Experimental; Ovary; Rats; Receptors, Steroid | 1977 |
Angiogenesis: a marker for neoplastic transformation of mammary papillary hyperplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Hyperplasia; Iris; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Papilloma; Transplantation, Heterologous; Urethane | 1977 |
Marked instability of character of cloned epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cell Line; Chromosomes; Clone Cells; Culture Media; Epithelial Cells; Epithelium; Hydrocortisone; Karyotyping; Mammary Neoplasms, Experimental; Rats | 1977 |
Antagonism of development and growth of 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors by the antiestrogen U 23,469 and effects on estrogen and progesterone receptors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Cell Nucleus; Cytosol; Estrogens; Female; Mammary Neoplasms, Experimental; Naphthalenes; Propylene Glycols; Rats; Receptors, Estrogen; Receptors, Progesterone; Time Factors | 1977 |
Progesterone and progesterone receptors in experimental breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Ovary; Progesterone; Rats; Receptors, Estrogen; Receptors, Progesterone; Recurrence; Remission, Spontaneous | 1977 |
The effect of an aromatase inhibitor, 4-hydroxy-4-androstene-3,17-dione, on estrogen-dependent processes in reproduction and breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Aromatase Inhibitors; Body Weight; Embryo Implantation; Estrogens; Female; Humans; Male; Mammary Neoplasms, Experimental; Pregnancy; Proestrus; Rats | 1977 |
Early increases in ribonucleic acid polymerase activities of dimethylbenzanthracene-induced mammary tumour nuclei in response to oestradiol-17beta and tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Cytoplasm; DNA-Directed RNA Polymerases; Estradiol; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Stilbenes; Tamoxifen; Time Factors | 1977 |
Morphology, growth characteristics and oestrogen-binding capacity of DMBA-induced mammary tumours from ovariectomized rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Castration; Female; Lipid Metabolism; Mammary Neoplasms, Experimental; Mitosis; Rats; Receptors, Estrogen | 1977 |
Effects of oestradiol-17beta and tamoxifen on nuclear oestradiol-17beta receptors in DMBA-induced rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Stilbenes; Tamoxifen; Temperature | 1977 |
Oestrogen receptor activity and endocrine status in DMBA-induced rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Estradiol; Estrogens; Estrus; Female; Mammary Neoplasms, Experimental; Perphenazine; Pregnancy; Prolactin; Rats; Receptors, Estrogen | 1977 |
Mammary tumorigenesis in chemical carcinogen-treated mice. VII. Prolactin and progesterone levels in BALB/c mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Adrenalectomy; Age Factors; Animals; Castration; Circadian Rhythm; Estrus; Female; Mammary Neoplasms, Experimental; Methylcholanthrene; Mice; Mice, Inbred BALB C; Ovary; Pituitary Gland; Precancerous Conditions; Pregnancy; Progesterone; Prolactin | 1977 |
[Synergistic therapeutic effect of adriamycin with 5-fluor-uracil, with prednisolon and with cyclophosphamide on chemically induced mammary cancer of the rat (author's transl)].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Mammary Neoplasms, Experimental; Methotrexate; Prednisolone; Rats; Vincristine | 1977 |
Modification of superoxide dismutase in rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Ischemia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Neoplasm Proteins; Oxygen; Rats; Superoxide Dismutase | 1977 |
Alternate fluctuations of leucine and thymidine incorporation by mammary tumors in rats during the estrous cycle.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; DNA, Neoplasm; Estrogens; Estrus; Female; Leucine; Mammary Neoplasms, Experimental; Neoplasm Proteins; Pregnancy; Prolactin; Rats; Thymidine; Time Factors | 1977 |
Increase in serum and tissue glycosyltransferases and glycosidases in tumor-bearing rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma 256, Walker; Female; Galactosyltransferases; Liver; Mammary Neoplasms, Experimental; Rats; Sialyltransferases; Transferases | 1977 |
Inhibition by neonatal hypothalamic estrogen implantation of carcinogen-induced mammary tumorigenesis in female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Age Factors; Animals; Corpus Luteum; Drug Implants; Estrogens; Estrus; Female; Hypothalamus; Hypothalamus, Anterior; Hypothalamus, Middle; Hypothalamus, Posterior; Infertility, Female; Mammary Neoplasms, Experimental; Organ Size; Ovary; Pregnancy; Rats; Vagina | 1977 |
Mammary tumor and leukemia in male Sprague-Dawley rats evoked by a series of intragastric administration of 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma, Papillary; Animals; Benz(a)Anthracenes; Carcinoma, Squamous Cell; Ear Neoplasms; Hematopoietic Stem Cells; Leukemia, Experimental; Leukemia, Myeloid; Male; Mammary Neoplasms, Experimental; Papilloma; Rats | 1977 |
Transplantable mammary tumors in Wistar/Furth rats: development, antigenicity, and effect of hormone manipulations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Estrogens; Female; Lymphocyte Activation; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Progesterone; Rats; Rats, Inbred WF; Transplantation, Isogeneic | 1977 |
Detection of casein messenger RNA in hormone-dependent mammary cancer by molecular hybridisation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Caseins; Castration; Cell Line; Estradiol; Female; Lactation; Mammary Neoplasms, Experimental; Mice; Nafoxidine; Nucleic Acid Hybridization; Pregnancy; Prolactin; Rats; RNA, Messenger | 1977 |
The effect of ovariectomy, tamoxifen and the combination adriamycin and 5-FU on 7,12-dimethylbenz(a)anthracene induced mammary cancer of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Mammary Neoplasms, Experimental; Rats; Remission, Spontaneous; Stilbenes; Tamoxifen | 1977 |
Single versus fractionated doses of X-radiation and their effect on mammary carcinoma in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Radiotherapy Dosage; Rats; Transplantation, Homologous; X-Rays | 1977 |
Dose dependence of immunopotentiation and tumor regression induced by levamisole.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Female; Immunity; Immunosuppression Therapy; In Vitro Techniques; Levamisole; Lymphocyte Activation; Lymphocytes; Mammary Neoplasms, Experimental; Mitogens; Rats; Spleen | 1977 |
Prolactin binding to 7,12-dimethylbenz(a)anthracene-induced mammary tumors and liver in diabetic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Diabetes Mellitus, Experimental; Female; Insulin; Liver; Mammary Neoplasms, Experimental; Nucleotidases; Prolactin; Rats | 1977 |
Effect of 7,12-dimethylbenz(a)anthracene on the binding of aminoacyl transfer RNA in rat liver.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; DDT; Female; In Vitro Techniques; Liver; Mammary Neoplasms, Experimental; Methionine; Peptide Biosynthesis; Peptide Elongation Factors; Peptide Initiation Factors; Phenylalanine; Rats; Ribosomes; RNA, Transfer, Amino Acyl | 1977 |
Histopathogenesis of 7,12-diemthylbenz(a)anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adipose Tissue; Animals; Benz(a)Anthracenes; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats | 1977 |
[Steroid excretion in rats with mammary gland tumors].
Topics: 17-Ketosteroids; 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Female; Mammary Neoplasms, Experimental; Rats; Time Factors | 1977 |
Estrogen receptors in DMBA-induced rat mammary tumors before and after ovariectomy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Cytoplasm; Female; Mammary Neoplasms, Experimental; Ovary; Rats; Receptors, Estrogen; Remission, Spontaneous | 1977 |
Effects of a gonadotropin-releasing hormone (GnRH) analogue (A-43818) on 7, 12- dimethylbenz (a)anthracene-induced rat mammary tumors. Histological and endocrine studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Female; Gonadotropins, Pituitary; Hormones; Mammary Neoplasms, Experimental; Pituitary Gland; Pituitary Hormone-Releasing Hormones; Rats | 1977 |
Danazol therapy in hormone-sensitive mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Danazol; Endocrine Glands; Female; Hormones; Mammary Neoplasms, Experimental; Pregnadienes; Rats; Remission, Spontaneous | 1977 |
Oestrogen-induced protein in rat mammary tumour and uterus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Neoplasm Proteins; Rats; Uterus | 1977 |
7,12-Dimethylbenz[a]anthracene-induced alteration of mammary epithelial cell RNA-synthetic patterns in rat strains of high and low tumor incidence.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Fractionation; Cell Nucleolus; Cells, Cultured; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Female; In Vitro Techniques; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methods; Rats; RNA; RNA, Ribosomal; Species Specificity; Time Factors; Uridine | 1978 |
The specificity of the oestrogen receptor of DMBA-induced mammary tumours of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding, Competitive; Cell Nucleus; Cytosol; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Subcellular Fractions | 1977 |
Multiple autotransplantation of rat mammary induced by 7,12-dimethylbenz[a]anthracene: brief communication.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Female; Graft Survival; Leucine; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Rats; Receptors, Estrogen; Transplantation, Autologous; Transplantation, Homologous | 1978 |
Relationship between insulin and estrogen binding to growth response in 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Diabetes Mellitus, Experimental; Estradiol; Female; Mammary Neoplasms, Experimental; Ovary; Rats; Receptor, Insulin; Receptors, Estrogen | 1978 |
Oestrogen receptors in transplantable ovary-independent, mammary tumours of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Estradiol; Female; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Ovary; Prolactin; Rats; Receptors, Estrogen; Transplantation, Homologous | 1978 |
Age-related modification of 7,12-dimethylbenz[a]anthracene binding to rat mammary gland DNA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Benz(a)Anthracenes; DNA; Dose-Response Relationship, Drug; Female; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Organ Specificity; Rats | 1978 |
Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetonitriles; Animals; Benz(a)Anthracenes; Diet; Female; Indoles; Mammary Neoplasms, Experimental; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Rats; Stomach Neoplasms | 1978 |
Perphenazine and testosterone metabolism by mammary tumours in oophorectomized rats [proceedings].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Female; Mammary Neoplasms, Experimental; Perphenazine; Prolactin; Rats; Testosterone | 1978 |
[Alteration in the secretion of anterior pituitary hormones during dimethylbenzathracene induction of mammary tumors in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Follicle Stimulating Hormone; Growth Hormone; Luteinizing Hormone; Mammary Neoplasms, Experimental; Pituitary Hormones, Anterior; Prolactin; Rats; Thyrotropin | 1977 |
Interaction of androgens with oestradiol-17beta receptor proteins in DMBA-induced mammary tumours--a possible oncolytic mechanism.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androgens; Animals; Binding, Competitive; Cytoplasm; Estradiol; Female; Mammary Neoplasms, Experimental; Neoplasms; Rats; Receptors, Estrogen | 1978 |
Inhibition of DMBA-induced carcinogenesis by phenformin in the mammary gland of rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blood Glucose; Cholesterol; Fatty Acids, Nonesterified; Insulin; Mammary Neoplasms, Experimental; Phenformin; Rats | 1978 |
Effect of estradiol and prolactin on galactosyltransferase and alpha-lactalbumin activities in rat mammary gland and mammary tumor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Galactosyltransferases; Lactalbumin; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Ovary; Pregnancy; Prolactin; Rats | 1978 |
Studies with carcinogen-induced mammary carcinoma of the rat. The trial of auto-immunization to inhibit tumor formation after the surgical removal of tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Carcinoma, Papillary; Female; Hemagglutination Tests; Immunization; Mammary Neoplasms, Experimental; Methylcholanthrene; Neoplasm Recurrence, Local; Rabbits; Rats; Sheep | 1975 |
Site of origin of mammary tumors induced by 7,12-dimethylbenz(a)anthracene in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Administration, Topical; Animals; Benz(a)Anthracenes; Injections, Intravenous; Male; Mammary Neoplasms, Experimental; Rats; Time Factors | 1975 |
Inhibitory effect of actinomycin D on the inductio of rat mammary tumors by in vitro exposure to 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Dactinomycin; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats | 1975 |
[Quantitative changes in the fat-soluble products of 9,10-dimethyl-1,2-benzanthracene-h3 metabolism during induction of mammary gland cancer in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Kinetics; Lipid Metabolism; Liver; Mammary Neoplasms, Experimental; Rats; Spleen; Tritium | 1975 |
High dietary fat, elevation of rat serum prolactin and mammary cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Dietary Fats; Estrus; Female; Humans; Infant, Newborn; Iodine Radioisotopes; Mammary Neoplasms, Experimental; Pregnancy; Proestrus; Prolactin; Radioimmunoassay; Rats | 1975 |
Poly(rA): oligo(dT)-directed DNA polymerase activity in carcinogen induced rat mammary tumors and in normal tissues.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Cytoplasm; DNA Nucleotidyltransferases; Female; Hydroxyapatites; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methods; Molecular Weight; Rats; Templates, Genetic | 1975 |
Inhibitory effect of L-arginine on growth of rat mammary tumors induced by 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Arginine; Diet; Female; Mammary Neoplasms, Experimental; Rats | 1975 |
Is there any association between elevated serum prolactin level and mammary adenocarcinoma induced by 7,12-dimethylbenz(alpha)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Coumarins; Female; Liver; Mammary Neoplasms, Experimental; Mixed Function Oxygenases; Phenobarbital; Prolactin; Rats; Stimulation, Chemical | 1975 |
Effects of 7,12-dimethylbenz(a)anthracene on rat mammary epithelial cell macromolecules: a time study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Nucleus; Cell Transformation, Neoplastic; Cytosol; DNA; Epithelial Cells; Epithelium; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Proteins; Rats; RNA; Time Factors | 1975 |
Effects of exposure of neonatal mice to 17beta-estradiol on subsequent age-incidence and morphology of carcinogen-induced mammary dysplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Age Factors; Animals; Animals, Newborn; Breast Neoplasms; Castration; Cysts; Estradiol; Female; Hyperplasia; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Pituitary Gland; Precancerous Conditions; Transplantation, Homologous | 1975 |
Protection by 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) against mammary tumors and leukemia during prolonged feeding of 7,12-dimethylbenz(a)anthracene to female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; DDT; Drug Synergism; Female; Leukemia, Experimental; Leukemia, Myeloid; Malathion; Mammary Neoplasms, Experimental; Rats | 1975 |
Temperature and blood flow measurements in and around 7,12-dimethylbenz(a)anthracene-induced tumor and Walker 256 carcinosarcomas in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Blood Flow Velocity; Carcinoma 256, Walker; Circadian Rhythm; Female; Mammary Neoplasms, Experimental; Rats; Regional Blood Flow; Skin; Skin Temperature; Temperature | 1975 |
Regional distribution of DMBA-induced mammary tumours in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abdomen; Animals; Benz(a)Anthracenes; Female; Mammary Neoplasms, Experimental; Rats; Thorax | 1975 |
Dietary fat and growth promotion of rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Cell Line; Dietary Fats; Dose-Response Relationship, Drug; Estradiol; Estrogens; Mammary Neoplasms, Experimental; Models, Biological; Prolactin; Rats | 1975 |
Metabolism of (4-14C)estradiol by 7,12-dimethylbenz(a) anthracene-induced mammary tumor peroxidase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amitrole; Animals; Ascorbic Acid; Azides; Benz(a)Anthracenes; Catalase; Cyanides; Estradiol; Ethylmaleimide; Female; Iodoacetamide; Kinetics; Lactoperoxidase; Mammary Neoplasms, Experimental; Peroxidases; Rats | 1975 |
DMBA-induced mammary tumours in locally irradiated rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Forelimb; Head; Hindlimb; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Neoplasms, Radiation-Induced; Radiation Effects; Rats | 1975 |
Enhancement by prolactin of carcinogen induced mammary cancerigenesis in the male rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Synergism; Male; Mammary Neoplasms, Experimental; Pituitary Gland; Prolactin; Rats; Time Factors; Transplantation, Homologous | 1975 |
Prolactin and estrogen dependency of rat mammary cancers at early and late stages of development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Ergolines; Estradiol; Estrogens; Female; Haloperidol; Mammary Neoplasms, Experimental; Prolactin; Rats | 1976 |
Stimulation of carcinogen-induced mammary tumor growth in rats by adrenalectomy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Animals; Ergolines; Female; Hydrocortisone; Mammary Neoplasms, Experimental; Prolactin; Rats | 1976 |
The effect of synthetic anti-oestrogens on the growth and biochemistry of rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Estradiol; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Stilbenes; Tamoxifen | 1975 |
Effect of dietary fats on the incidence of 7,12-dimethylbenz(a)-anthracene-induced tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Body Weight; Dietary Fats; Fats, Unsaturated; Female; Mammary Neoplasms, Experimental; Rats; Time Factors | 1976 |
Correlation between hormone binding and growth response of rat mammary tumor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biopsy; Bromocriptine; Estradiol; Female; Insulin; Mammary Neoplasms, Experimental; Prolactin; Rats | 1976 |
Effects on insulin, prolactin, progesterone, and estradiol on DNA synthesis in organ culture of 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; DNA, Neoplasm; Estradiol; Female; Insulin; Mammary Neoplasms, Experimental; Mitosis; Organ Culture Techniques; Progesterone; Prolactin; Rats | 1976 |
Inhibition of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis by retinyl acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Adenoma; Animals; Benz(a)Anthracenes; Estrogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Vitamin A | 1976 |
[The influence of thyroid and antithyroid preparations on the development of induced breast cancer].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Mammary Neoplasms, Experimental; Methylthiouracil; Potassium Iodide; Rats; Thyroxine | 1976 |
Circadian variations in 32P uptake of DMBA-induced mammary tumour and Walker carcinosarcoma in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Temperature; Carcinoma 256, Walker; Circadian Rhythm; Darkness; Female; Mammary Neoplasms, Experimental; Phosphorus; Rats; Skin | 1976 |
Therapy of dimethylbenzanthracene-induced mammary carcinomas in the rat by selective inhibition of steroidogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Androstenols; Animals; Body Weight; Castration; Corticosterone; Cyanoketone; Drug Therapy, Combination; Female; Hydroxysteroid Dehydrogenases; Mammary Neoplasms, Experimental; Multienzyme Complexes; Rats; Steroid Isomerases; Steroids | 1976 |
Changes in morphology and hormone dependency following transplantation of rat 9,10-Dimethyl-1,2-benzanthracene-induced mammary adenocarcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Castration; Estradiol; Female; Fibrosarcoma; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Transplantation, Homologous | 1976 |
Neonatal modification of endocrine functions and mammary carcinogenesis in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Castration; Female; Follicle Stimulating Hormone; Lactation; Luteinizing Hormone; Mammary Neoplasms, Experimental; Ovary; Pituitary Gland; Pregnancy; Prolactin; Rats; Testosterone | 1976 |
Prolactin binding to mammary gland, 7,12-dimethylbenz(a)-anthracene-induced mammary tumors, and liver in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetonitriles; Animals; Ergolines; Estradiol; Estrogen Antagonists; Female; Lactation; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Pregnancy; Pregnancy, Animal; Prolactin; Rats | 1976 |
Effect of tamoxifen (ICI 46,474) on initiation and growth of DMBA-induced rat mammary carcinomata.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Cell Division; Estradiol; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Stilbenes; Tamoxifen; Time Factors | 1976 |
Effects of prolactin and growth hormone on DNA synthesis of rat mammary carcinomas in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; DNA, Neoplasm; Female; Growth Hormone; Mammary Neoplasms, Experimental; Organ Culture Techniques; Prolactin; Rats | 1976 |
Heterogeneity in in vitro response to progesterone and melphalan of mammary tumours induced in the rat by 7,12-DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Cells, Cultured; Female; Mammary Neoplasms, Experimental; Melphalan; Progesterone; Rats | 1976 |
In vitro effects of prolactin upon testosterone metabolism by rat mammary adenocarcinomata.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Androstane-3,17-diol; Animals; Dihydrotestosterone; Female; In Vitro Techniques; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Prolactin; Rats; Testosterone; Thymectomy; Transplantation, Isogeneic | 1976 |
Effects of oestradiol - 17beta and tamoxifen on total and accessible cytoplasmic oestradiol - 17beta receptors in DMBA-induced rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cytoplasm; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Stilbenes; Tamoxifen; Temperature; Time Factors | 1976 |
Endocrine-dependent rat mammary tumor regression: use of a gonadotropin releasing hormone analog.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Castration; Female; Gonadotropin-Releasing Hormone; Hormones; Mammary Neoplasms, Experimental; Rats | 1976 |
Hormonal status and testosterone metabolism of DMBA-induced rat mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstane-3,17-diol; Animals; Castration; DNA; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Testosterone | 1976 |
Effects of high hoses of estrogen on prolactin-binding activity and growth of carcinogen-induced mammary cancers in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Dose-Response Relationship, Drug; Estradiol; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Receptors, Estrogen | 1976 |
Suppression of 7,12-dimethylbenz(alpha) anthracene-induced breast carcinoma by coumarin in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adrenal Cortex; Animals; Benz(a)Anthracenes; Coumarins; Dose-Response Relationship, Drug; Female; Hydroxylation; Liver; Mammary Neoplasms, Experimental; Prolactin; Rats; Time Factors | 1976 |
Effect of insulin on glucose transport in DMBA-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biological Transport; Depression, Chemical; Dose-Response Relationship, Drug; Female; Glucose; Insulin; Mammary Neoplasms, Experimental; Rats; Stimulation, Chemical | 1976 |
Plasma hormone levels and the incidence of carcinogen-induced mammary tumours in two strains of rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Gonadal Steroid Hormones; Mammary Neoplasms, Experimental; Prolactin; Rats; Rats, Inbred Strains | 1976 |
Mammary tumorigenesis in chemical carcinogen-treated mice. IV. Induction of mammary ductal hyperplasias.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Age Factors; Animals; Female; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Precancerous Conditions; Urethane | 1976 |
[Studies on biological characterization of mammary tumours of the sprague-dawley-rat in the syngeneic tumour-host system. I. Spontaneous primary mammary tumours and tumours induced by oral and intravenous application of DMBA (author's transl)].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Administration, Oral; Animals; Benz(a)Anthracenes; Female; Injections, Intravenous; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1976 |
Tests for tumor induction by antitumor agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Carcinogens; Dactinomycin; Daunorubicin; DNA; Female; Hydroxyurea; Mammary Neoplasms, Experimental; Mice; Mice, Inbred A; Neoplasms, Experimental; Rats | 1975 |
Potent inhibitory activity of a new antiestrogen, RU 16 117, on the development and growth of DMBA-induced rat mammary adenocarcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Binding, Competitive; Estradiol; Estrogen Antagonists; Ethinyl Estradiol; Female; Mammary Neoplasms, Experimental; Ovary; Progesterone Congeners; Prolactin; Rats; Receptors, Estrogen; Receptors, Progesterone | 1976 |
Effect of some rifamycin derivatives on chemically-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Interactions; Female; Lymphoma; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Rats; Rifampin; Rifamycins | 1976 |
[Influence of long-term lactation on 7,12-dimethylbenz(a)anthracene (DMBA) induced rat mammary tumor (author's transl)].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Estrus; Female; Labor, Obstetric; Lactation; Mammary Neoplasms, Experimental; Pregnancy; Rats; Time Factors | 1976 |
[Studies on biological characterization of mammary tumours of the Sprague-Dawley-Rat in the syngeneic tumour-host system. II. Establishment of transplantable mammary tumour lines (author's transl)].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenofibroma; Animals; Carcinoma; Cell Line; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Rats | 1976 |
Antiestrogenic and antitumor properties of tamoxifen in laboratory animals.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antineoplastic Agents; Binding, Competitive; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Stilbenes; Tamoxifen | 1976 |
Regression of "hormone-independent" DMBA-induced mammary carcinomas in response to GP 48989 and its effects on hormone receptors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenofibroma; Animals; Benz(a)Anthracenes; Carcinoma; Castration; Cytoplasm; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Thiazoles; Thiazolidines | 1976 |
A possible modulatory influence of melatonin on representative phase I and II drug metabolizing enzymes in 9,10-dimethyl-1,2-benzanthracene induced rat mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cytochrome P-450 Enzyme System; Cytochromes b5; Female; Glutathione; Glutathione Transferase; Mammary Neoplasms, Experimental; Melatonin; Rats | 1992 |
Effects of high and low dietary fat and indomethacin on tumour growth, hormone receptor status and growth factor expression in DMBA-induced rat breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Bromodeoxyuridine; Cell Division; Dietary Fats, Unsaturated; Female; Growth Substances; Immunohistochemistry; Incidence; Indomethacin; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone | 1992 |
Preclinical studies on the anticancer activity of the somatostatin analogue octreotide (SMS 201-995).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Autoradiography; Disease Models, Animal; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Octreotide; Pancreatic Neoplasms; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Somatostatin; Tumor Cells, Cultured | 1992 |
Influence of estrogen and progesterone on the induction of mammary carcinomas by 7,12-dimethylbenz(a)anthracene in ovariectomized rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Disease Models, Animal; Estradiol; Female; Mammary Neoplasms, Experimental; Ovariectomy; Ovary; Progesterone; Rats; Rats, Sprague-Dawley | 1992 |
Down-regulation of tenascin expression by antiprogestins during terminal differentiation of rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Adhesion Molecules, Neuronal; Cell Differentiation; Extracellular Matrix Proteins; Female; Gonanes; Immunohistochemistry; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Progesterone; Rats; Tamoxifen; Tenascin; Uterus | 1992 |
Antitumour synergism between non-toxic dietary combinations of isotretinoin and glucarate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Female; Fenretinide; Glucaric Acid; Isotretinoin; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tretinoin | 1992 |
1 alpha-hydroxyvitamin D3, hypercalcemia, and growth suppression of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Female; Fluorouracil; Hydroxycholecalciferols; Hypercalcemia; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Rats; Rats, Sprague-Dawley; Weight Loss | 1992 |
Inhibition of 7,12-dimethylbenz[a]anthracene-induced mammary tumors and DNA adducts by garlic powder.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Body Weight; DNA; DNA Adducts; Eating; Female; Garlic; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Plants, Medicinal; Rats; Rats, Sprague-Dawley | 1992 |
Mammary carcinoma suppressor and susceptibility genes in the Wistar-Kyoto rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Crosses, Genetic; Drug Resistance; Female; Genes, Tumor Suppressor; Hybridization, Genetic; Male; Mammary Neoplasms, Experimental; Rats; Rats, Inbred F344; Rats, Inbred Strains; Rats, Inbred WF; Rats, Inbred WKY | 1992 |
Effects of a long-chain fatty amine on mammary carcinogenesis induced in female Sprague-Dawley rats by DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amines; Animals; Body Weight; Corn Oil; Female; Mammary Neoplasms, Experimental; Protein Kinase C; Random Allocation; Rats; Rats, Sprague-Dawley | 1992 |
Mammary cancer prevention by regular garlic and selenium-enriched garlic.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Female; Garlic; Kidney; Liver; Mammary Neoplasms, Experimental; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Selenium | 1992 |
Immunohistochemical expression of monoclonal antibodies (epi-1 and myo-1) derived from human breast cancer against rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Adenoma; Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Breast Neoplasms; Female; Humans; Immunohistochemistry; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 1992 |
Differential expression of cAMP-kinase subunits is correlated with growth in rat mammary carcinomas and uterus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Injections, Subcutaneous; Isoenzymes; Mammary Neoplasms, Experimental; Ovariectomy; Ovary; Protein Kinases; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Neoplasm | 1992 |
Pregnancy-induced antitumor cytotoxicity of T cell-rich fraction against mammary adenocarcinoma cells in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; B-Lymphocytes; Cytotoxicity, Immunologic; Female; Male; Mammary Neoplasms, Experimental; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Spleen; T-Lymphocytes | 1992 |
Specific stimulation by estradiol of tissue-type plasminogen activator production in 7,12-dimethylbenz[a]anthracene-induced rat mammary tumor cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Enzyme Induction; Estradiol; Female; Fibrocystic Breast Disease; Mammary Neoplasms, Experimental; Molecular Sequence Data; Ovariectomy; Rats; Rats, Sprague-Dawley; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator | 1992 |
Effects of switching from a high-fat diet to a low-fat diet on tumor proliferation and cell kinetics of 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Bromodeoxyuridine; Cell Cycle; Cell Division; Dietary Fats; DNA, Neoplasm; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1992 |
Inhibition by butylated hydroxytoluene and its oxidative metabolites of DMBA-induced mammary tumorigenesis and of mammary DMBA-DNA adduct formation in vivo in the female rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Anticarcinogenic Agents; Butylated Hydroxytoluene; Chromatography, Thin Layer; DNA; DNA Adducts; DNA, Neoplasm; Female; Hydroxylation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Microsomes; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1992 |
Biological activities of trimethylselenonium as influenced by arsenite.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Arsenic; Arsenites; Diet; Drug Synergism; Female; Glutathione Peroxidase; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenium; Selenium Compounds | 1992 |
Demonstration of a possible link between high grade malignancy in dimethylbenz[a]anthracene-induced rat mammary carcinoma and increased urokinase plasminogen activator content.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; DNA; Female; Mammary Neoplasms, Experimental; Ploidies; Rats; Rats, Inbred Strains; Receptors, Estrogen; Survival Rate; Urokinase-Type Plasminogen Activator | 1992 |
Treatment of experimental DMBA induced mammary carcinoma with Cetrorelix (SB-75): a potent antagonist of luteinizing hormone-releasing hormone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Gonadotropin-Releasing Hormone; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Triptorelin Pamoate | 1992 |
[Experimental study of combination medical endocrine therapy on DMBA-induced mammary tumor, with special reference to the effect of drug-dose on various factors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Organ Size; Rats; Tamoxifen | 1992 |
Antitumor effects of SMANCS on rat mammary tumor induced by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Erythrocyte Count; Female; Hemoglobins; Maleic Anhydrides; Mammary Neoplasms, Experimental; Platelet Count; Polystyrenes; Rats; Rats, Inbred Strains; Zinostatin | 1992 |
Antitumour activity of folligen, a novel gonadotropin-releasing hormone analogue against DMBA-induced tumours in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Buserelin; Estradiol; Female; Gonadotropin-Releasing Hormone; Goserelin; Mammary Neoplasms, Experimental; Organ Size; Progesterone; Rats; Rats, Inbred Strains; Time Factors; Uterus | 1992 |
Differential effects of dietary linoleic acid on mouse skin-tumor promotion and mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Dinoprostone; Fatty Acids; Female; Linoleic Acid; Linoleic Acids; Mammary Neoplasms, Experimental; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Post-transcriptional regulation of urokinase plasminogen activator gene expression occurs in the nucleus of BC1 rat mammary tumor cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Blotting, Northern; Cell Line; Cycloheximide; DNA Probes; DNA, Neoplasm; Doxorubicin; Gene Expression; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Rats; RNA Processing, Post-Transcriptional; RNA, Neoplasm; Transcription, Genetic; Urokinase-Type Plasminogen Activator | 1992 |
Hormone control of total plasminogen activator activity is specific to malignant DMBA-induced rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Estrogens; Female; Mammary Neoplasms, Experimental; Ovariectomy; Plasminogen Activators; Progesterone; Rats; Receptors, Estrogen | 1992 |
RU54115, a tight-binding aromatase inhibitor potentially useful for the treatment of breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrenes; Estrogen Antagonists; Female; Gonadotropins, Equine; Humans; Kinetics; Mammary Neoplasms, Experimental; Microsomes; Molecular Structure; Placenta; Pregnancy; Rats; Rats, Inbred Strains | 1992 |
Inhibition of 7,12-dimethylbenz(a)anthracene-induced tumors and DNA adduct formation in the mammary glands of female Sprague-Dawley rats by the synthetic organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Deoxyribonucleosides; DNA; DNA Adducts; Female; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Organoselenium Compounds; Rats; Rats, Inbred Strains | 1992 |
Transcriptional and posttranscriptional activation of urokinase plasminogen activator gene expression in metastatic tumor cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; DNA; Down-Regulation; Enzyme Activation; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Molecular Sequence Data; Rats; Rats, Inbred F344; RNA, Messenger; Transcription, Genetic; Transcriptional Activation; Urokinase-Type Plasminogen Activator | 1992 |
Effect of the amount of dietary fat on the development of mammary tumors in BALB/c-MTV mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Dietary Fats; Fatty Acids; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C | 1992 |
The effect of castration on the synthesis and secretion of proteins in 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Molecular Weight; Neoplasm Proteins; Ovariectomy; Rats; Time Factors | 1992 |
Inhibition of 7,12-dimethylbenz[a]anthracene-induced lipid peroxidation and mammary tumor development in rats by vitamin E in conjunction with selenium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adipose Tissue; Animals; Chi-Square Distribution; Female; Lipid Peroxidation; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenium; Time Factors; Vitamin E | 1992 |
The effect of flaxseed supplementation on the initiation and promotional stages of mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Body Weight; Chi-Square Distribution; Female; Flour; Magnoliopsida; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Seeds | 1992 |
Stimulation of malignant growth in rodents by antidepressant drugs at clinically relevant doses.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amitriptyline; Animals; Antidepressive Agents; DNA; Fluoxetine; Lymphocyte Activation; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasms, Experimental | 1992 |
Limonene-induced regression of mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cyclohexenes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Limonene; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Terpenes | 1992 |
beta-Carotene-mediated inhibition of a DNA adduct induced by 7,12-dimethylbenz(a)anthracene and 7-hydroxymethyl-12-methylbenz(a)anthracene in mouse mammary gland in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Carotenoids; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C | 1992 |
Comparison of selenium and sulfur analogs in cancer prevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Betaine; Cystamine; Cysteamine; Cysteine; Diet; Female; Mammary Neoplasms, Experimental; Organoselenium Compounds; Rats; Rats, Inbred Strains; Selenocysteine | 1992 |
Chemoprevention of mammary carcinogenesis by hydroxylated derivatives of d-limonene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cyclohexane Monoterpenes; Cyclohexenes; Female; Hydroxylation; Limonene; Mammary Neoplasms, Experimental; Monoterpenes; Rats; Rats, Inbred WF; Structure-Activity Relationship; Terpenes | 1992 |
Hormonal regulation of plasminogen activator and peroxidase activities in 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors and the rat uterus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Estrogens; Female; Mammary Neoplasms, Experimental; Ovariectomy; Peroxidase; Plasminogen Activators; Rats; Rats, Inbred Strains; Uterus | 1991 |
Localization of peripheral benzodiazepine binding sites and diazepam-binding inhibitor (DBI) mRNA in mammary glands and dimethylbenz(a)antracene (DMBA)-induced mammary tumors in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Autoradiography; Diazepam Binding Inhibitor; Female; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Neuropeptides; Nucleic Acid Hybridization; Pregnancy; Rats; Rats, Inbred Strains; Receptors, GABA-A; RNA, Messenger | 1991 |
The mouse biliary glycoprotein gene (Bgp): partial nucleotide sequence, expression, and chromosomal assignment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Antigens, CD; Base Sequence; Carcinoembryonic Antigen; Cell Adhesion Molecules; Chromosome Mapping; Cricetinae; Cricetulus; Gene Expression Regulation, Neoplastic; Genes; Genes, Neoplasm; Genetic Markers; Glycoproteins; Humans; Hybrid Cells; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Molecular Sequence Data; Multigene Family; Neoplasm Proteins; Organ Specificity; RNA, Messenger; RNA, Neoplasm; Sequence Homology, Nucleic Acid | 1991 |
Chemically induced mammary gland adenomyoepitheliomas and myoepithelial carcinomas of mice. Immunohistochemical and ultrastructural features.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Adenocarcinoma; Animals; Female; Immunohistochemistry; Keratins; Mammary Neoplasms, Experimental; Mice; Microscopy, Electron; Myoepithelioma | 1990 |
Angiogenic factor of a rat mammary tumor cell line (RMT-1) (I). Secretion of two distinct angiogenic factors into serum-free conditioned medium by RMT-1 cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inducing Agents; Animals; Cell Division; Chick Embryo; Culture Media; DNA; Mammary Neoplasms, Experimental; Mice; Neovascularization, Pathologic; Rabbits; Rats; Tumor Cells, Cultured | 1991 |
Effects of low copper and high zinc intakes and related changes in Cu,Zn-superoxide dismutase activity on DMBA-induced mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Copper; Diet; Eating; Erythrocytes; Female; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Spectrophotometry, Atomic; Superoxide Dismutase; Zinc | 1991 |
Antitumor effect of 22-oxa-1 alpha,25-dihydroxyvitamin D3, a potent angiogenesis inhibitor, on rat mammary tumors induced by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Calcitriol; Calcium; Female; Mammary Neoplasms, Experimental; Neovascularization, Pathologic; Organ Size; Rats; Rats, Inbred Strains | 1991 |
Role of tamoxifen in the induction of hormone-independent rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tamoxifen | 1992 |
Iron deficiency alters DMBA-induced tumor burden and natural killer cell cytotoxicity in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Female; Iron; Iron Deficiencies; Killer Cells, Natural; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Spleen | 1992 |
Milk cream does not enhance 2,7-dimethylbenz[a]anthracene-induced mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Body Weight; Carcinoma; Cholesterol; Dietary Fats; Mammary Neoplasms, Experimental; Milk; Organ Size; Rats; Rats, Inbred Strains | 1992 |
The effect of dietary fat on the rapid development of mammary tumors induced by 7,12-dimethylbenz(a)anthracene in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Dietary Fats; Female; Linoleic Acid; Linoleic Acids; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Time Factors | 1992 |
Antitumoral and endocrine effects of (+)-vorozole in rats bearing dimethylbenzanthracene-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aromatase Inhibitors; Drug Administration Schedule; Drug Screening Assays, Antitumor; Estradiol; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Mammary Neoplasms, Experimental; Ovariectomy; Random Allocation; Rats; Rats, Inbred Strains; Triazoles | 1992 |
Effects of an androgenic derivative on pre-established mammary tumours chemically induced in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Danazol; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Ovary; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone | 1991 |
Caffeine inhibits development of benign mammary gland tumors in carcinogen-treated female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenofibroma; Animals; Caffeine; Carcinoma; Female; Fibrocystic Breast Disease; Mammary Neoplasms, Experimental; Ovariectomy; Parity; Rats; Rats, Inbred Strains | 1991 |
Flow cytometric analysis of oestrogen receptors in relation to histopathologic characteristics of DMBA-induced mammary tumours in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Female; Flow Cytometry; Mammary Neoplasms, Experimental; Microscopy, Electron; Rats; Rats, Inbred Strains; Receptors, Estradiol | 1991 |
Suppressive effect by melatonin on different phases of 9,10-dimethyl-1,2-benzanthracene (DMBA)-induced rat mammary gland carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Light; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Melatonin; Pineal Gland; Rats | 1991 |
Antitumor effects of droloxifene, a new antiestrogen drug, against 7,12-dimethylbenz(a)anthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cytosol; Estradiol; Estrogen Antagonists; Female; Iodine Radioisotopes; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Promegestone; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1991 |
Chemical form of selenium, critical metabolites, and cancer prevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Arsenic; Arsenites; Cysteine; Female; Glutathione Peroxidase; Liver; Mammary Neoplasms, Experimental; Organoselenium Compounds; Oxides; Rats; Rats, Inbred Strains; Selenious Acid; Selenium; Selenocysteine | 1991 |
Antitumor effects of a nonsteroidal aromatase inhibitor (CGS 16949A) on 7, 12-dimethylbenz[alpha]anthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Aromatase Inhibitors; Body Weight; Estradiol; Estrone; Fadrozole; Female; Imidazoles; Mammary Neoplasms, Experimental; Nitriles; Organ Size; Progesterone; Rats; Rats, Inbred Strains; Receptors, Estrogen; Testosterone; Uterus | 1991 |
Comparison of the effects of the irreversible aromatase inhibitor exemestane with atamestane and MDL 18962 in rats with DMBA-induced mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstadienes; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Cell Division; Dose-Response Relationship, Drug; Endocrine Glands; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Organ Size; Ovariectomy; Pargyline; Prolactin; Rats | 1991 |
A comparison of tocopherol and tocotrienol for the chemoprevention of chemically induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Vitamin E | 1991 |
Combination of blocking agents and suppressing agents in cancer prevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Allyl Compounds; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Cysteine; Drug Antagonism; Drug Synergism; Ellagic Acid; Female; Mammary Neoplasms, Experimental; Organoselenium Compounds; Quercetin; Rats; Rats, Inbred Strains; Selenium; Selenocysteine; Selenomethionine; Sulfides | 1991 |
The microvasculature of the 7,12-dimethylbenz(a)anthracene (DMBA)-induced rat mammary tumour. I. Vascular patterns as visualized by scanning electron microscopy of corrosion casts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capillaries; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Microcirculation; Microscopy, Electron, Scanning; Rats; Rats, Inbred Strains | 1991 |
A mammary cancer suppressor gene and its site of action in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Female; Genes, Tumor Suppressor; Homozygote; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Rats; Rats, Inbred Strains | 1991 |
Reduction of enhanced mammary carcinogenesis in LA/N-cp (corpulent) rats by energy restriction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blood Glucose; Body Composition; Body Weight; Cholesterol; Diet, Reducing; Female; Insulin; Mammary Neoplasms, Experimental; Obesity; Rats; Triglycerides | 1991 |
Facilitation of dimethylbenz[a]anthracene-induced rat mammary tumorigenesis by restraint stress: role of beta-endorphin, prolactin and naltrexone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta-Endorphin; Eating; Endorphins; Enkephalin, Methionine; Female; Immune System; Lymphocyte Activation; Mammary Neoplasms, Experimental; Naltrexone; Neurosecretory Systems; Prolactin; Rats; Rats, Inbred F344; Stress, Physiological | 1991 |
Effects of the prostaglandin synthetase inhibitor indomethacin on tumorigenesis, tumor proliferation, cell kinetics, and receptor contents of 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in Sprague-Dawley rats fed a high- or low-fat diet.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Cell Cycle; Cell Division; Cyclooxygenase Inhibitors; Dietary Fats; DNA, Neoplasm; Female; Flow Cytometry; Indomethacin; Kinetics; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Time Factors | 1991 |
Effect of canthaxanthin on chemically induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Canthaxanthin; Carotenoids; Diterpenes; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Retinyl Esters; Vitamin A | 1991 |
Increase of auto anti-phosphatidylinositol antibodies in plasma of female rats during the appearance of DMBA-induced malignant mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibody Affinity; Antibody Specificity; Autoantibodies; Enzyme-Linked Immunosorbent Assay; Female; Mammary Neoplasms, Experimental; Phosphatidylinositols; Rats; Rats, Inbred Strains; Reference Values; Time Factors | 1991 |
The danger of studying human chorionic gonadotrophin action or expression in animal models.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chorionic Gonadotropin; Humans; Mammary Neoplasms, Experimental | 1991 |
Effect of DMBA on the expression of prolactin receptors and IGF1 genes in rat mammary gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Blotting, Northern; Female; Gene Expression; Insulin-Like Growth Factor I; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptor, Insulin; Receptors, Prolactin | 1991 |
Influence of caffeine on development of benign and carcinomatous mammary gland tumors in female rats treated with the carcinogens 7,12-dimethylbenz(a)anthracene and N-methyl-N-nitrosourea.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Caffeine; Carcinogens; Drug Synergism; Feces; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains | 1991 |
Expression of a rat ovary-independent mammary tumor-associated antigen defined by a monoclonal antibody, TAK-B1.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Tumor-Associated, Carbohydrate; Electrophoresis, Polyacrylamide Gel; Female; Immunoenzyme Techniques; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Ovary; Rats; Rats, Inbred Strains; Skin | 1991 |
Effects of sequential and combined immuno-endocrine therapies using OK-432 (Picibanil) and tamoxifen on the growth of 7,12-dimethylbenz [alpha] anthracene-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Mammary Neoplasms, Experimental; Picibanil; Rats; Rats, Inbred Strains; Tamoxifen | 1991 |
Genetic control of susceptibility to diethylnitrosamine and dimethylbenzanthracene carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diethylnitrosamine; Female; Genetic Predisposition to Disease; Liver; Liver Neoplasms; Male; Mammary Neoplasms, Experimental; Necrosis; Neoplasms, Experimental; Rats | 1991 |
Serum poly(A)polymerase levels in rats during induction of mammary carcinoma with 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Polynucleotide Adenylyltransferase; Rats; Rats, Inbred Strains; Time Factors | 1991 |
Amine oxidase activities in rat breast cancer induced experimentally with 7,12-dimethylbenz(alpha)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Amine Oxidase (Copper-Containing); Animals; Clorgyline; Detergents; Female; Kinetics; Mammary Neoplasms, Experimental; Monoamine Oxidase; Rats; Rats, Inbred Strains; Subcellular Fractions | 1991 |
Comparative effects of omega-3 and omega-6 polyunsaturated fatty acids on protein metabolism in rats bearing the mammary adenocarcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carbon Radioisotopes; Dietary Fats; Fatty Acids, Nonesterified; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Fatty Acids, Unsaturated; Female; Fish Oils; Kinetics; Leucine; Liver; Mammary Neoplasms, Experimental; Muscle Proteins; Muscles; Proteins; Radioisotope Dilution Technique; Rats; Rats, Inbred F344; Regional Blood Flow; Safflower Oil | 1991 |
Effect of dietary kelp on lipid peroxidation and glutathione peroxidase activity in livers of rats given breast carcinogen DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents; Diet; Female; Glutathione Peroxidase; Immunohistochemistry; Lipid Peroxidation; Lipid Peroxides; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Seaweed; Selenium; Time Factors | 1991 |
The role of Ha-ras oncogenes in growth factor independence in rat mammary carcinoma cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Cell Division; Codon; DNA, Neoplasm; Exons; Genes, ras; Mammary Neoplasms, Experimental; Methylnitrosourea; Polymerase Chain Reaction; Rats; Transfection | 1991 |
Inhibition of 7,12-dimethylbenz(a)anthracene-induced mammary tumors and DNA adducts by dietary selenite.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; DNA; DNA Adducts; DNA, Neoplasm; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenium | 1991 |
Nd:YAG laser hyperthermia treatment of rat mammary adenocarcinoma in conjunction with surface cooling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Aerosols; Air; Aluminum Silicates; Animals; Body Temperature; Cryotherapy; Female; Hyperthermia, Induced; Laser Therapy; Mammary Neoplasms, Experimental; Neodymium; Oxygen; Rats; Rats, Inbred Strains; Skin Temperature; Thermometers; Water; Yttrium | 1991 |
Comparative study of the influence of pregnancy and hormonal treatment on mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Anticarcinogenic Agents; Chorionic Gonadotropin; Female; Mammary Neoplasms, Experimental; Pregnancy; Pregnancy Complications, Neoplastic; Rats; Rats, Inbred Strains | 1991 |
Enhancement of pulmonary tumour seeding by human coagulation factors II, IX, X--an investigation into the possible mechanisms involved.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cell Division; Factor IX; Factor X; Female; Humans; Idoxuridine; Iodine Radioisotopes; Lung Neoplasms; Mammary Neoplasms, Experimental; Neoplasm Metastasis; Prothrombin; Rats; Rats, Inbred F344; Tumor Stem Cell Assay | 1991 |
Ethanol consumption and DMBA-induced mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alcohol Drinking; Animals; Cocarcinogenesis; DNA; Energy Intake; Epithelium; Ethanol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1991 |
Stimulation of in vivo tumor growth and phorbol ester-induced inflammation by N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine HCl, a potent ligand for intracellular histamine receptors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Drug Synergism; Epithelium; Female; Histamine Antagonists; Hyperplasia; Inflammation; Leukemia L5178; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred DBA; Mitotic Index; Phenyl Ethers; Rats; Rats, Inbred Strains; Receptors, Histamine; Skin; Tetradecanoylphorbol Acetate | 1991 |
Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumorigenesis and of in vivo formation of mammary DMBA-DNA adducts by rosemary extract.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Body Weight; Condiments; DNA; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Plant Extracts; Rats; Rats, Inbred Strains | 1991 |
Mammary cancer prevention by conjugated dienoic derivative of linoleic acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Butylated Hydroxytoluene; Female; Glucuronosyltransferase; Linoleic Acid; Linoleic Acids; Lipid Peroxidation; Mammary Neoplasms, Experimental; Phospholipids; Rats; Rats, Inbred Strains; Vitamin E | 1991 |
Comparative dose-response tumorigenicity studies of dibenzo[alpha,l]pyrene versus 7,12-dimethylbenz[alpha]anthracene, benzo[alpha]pyrene and two dibenzo[alpha,l]pyrene dihydrodiols in mouse skin and rat mammary gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogenicity Tests; Carcinogens; Dihydroxydihydrobenzopyrenes; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Mice; Skin Neoplasms | 1991 |
The effect of diet, exercise and 7,12-dimethylbenz(a)anthracene on food intake, body composition and carcass energy levels in virgin female BALB/c mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Composition; Diet; Diet, Atherogenic; Eating; Energy Metabolism; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Physical Exertion; Sexual Maturation | 1991 |
Reduced energy intake and moderate exercise reduce mammary tumor incidence in virgin female BALB/c mice treated with 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Eating; Energy Metabolism; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Physical Exertion; Sexual Maturation | 1991 |
Influence of diet on breast cancer size and morphology in rats treated with DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cell Division; Cell Transformation, Neoplastic; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methionine; Rats; Rats, Inbred Strains | 1991 |
The somatostatin analog Sandostatin (SMS201-995) in treatment of DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Buserelin; Drug Screening Assays, Antitumor; Female; Mammary Neoplasms, Experimental; Octreotide; Pituitary Hormones, Anterior; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Somatostatin; Receptors, Steroid | 1990 |
New antitumor promoters: (-)-epigallocatechin gallate and sarcophytols A and B.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Catechin; Cnidaria; Cocarcinogenesis; Diterpenes; Female; Flavonoids; Lyngbya Toxins; Mammary Neoplasms, Experimental; Mice; Skin Neoplasms; Tea | 1990 |
Influence of caloric restriction and exercise on tumorigenesis in rats.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Colonic Neoplasms; Diet, Reducing; Dietary Fats; Dimethylhydrazines; Female; Male; Mammary Neoplasms, Experimental; Physical Conditioning, Animal; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1990 |
Activity of methylated forms of selenium in cancer prevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arsenic; Azoles; Betaine; Drug Synergism; Female; Isoindoles; Mammary Neoplasms, Experimental; Organoselenium Compounds; Rats; Rats, Inbred Strains; Selenious Acid; Selenium | 1990 |
Relationship between metastatic ability and H-ras oncogene expression in rat mammary cancer cells transfected with the v-H-ras oncogene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Southern; Gene Expression Regulation, Neoplastic; Genes, ras; Mammary Neoplasms, Experimental; Neoplasm Metastasis; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Rats; Rats, Inbred Strains; Transfection | 1990 |
Dietary olive and safflower oils in promotion of DMBA-induced mammary tumorigenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Body Weight; Carcinogens; Dietary Fats, Unsaturated; Female; Insulin-Like Growth Factor I; Linoleic Acid; Linoleic Acids; Liver; Mammary Neoplasms, Experimental; Olive Oil; Organ Size; Plant Oils; Rats; Rats, Inbred Strains; Safflower Oil; Spleen | 1990 |
Effects of OK-432 (Picibanil) on estrogen receptor levels and tamoxifen treatment in 7,12-dimethylbenz[a]anthracene-induced rat mammary cancers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biological Products; Female; Mammary Neoplasms, Experimental; Picibanil; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen | 1990 |
Influence of strain and sex on the local development of mammary tumors induced by direct application of DMBA powder to rat mammary glands.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Administration, Topical; Animals; Disease Models, Animal; Female; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Orchiectomy; Ovariectomy; Rats; Rats, Inbred Strains; Sex Characteristics | 1990 |
Effect of dietary butylated hydroxytoluene on the in vivo distribution, metabolism and DNA-binding of 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Butylated Hydroxytoluene; Diet; DNA; Epoxide Hydrolases; Female; Glutathione Transferase; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tissue Distribution | 1990 |
The effect of four chemical forms of selenium on mammary tumor incidence in BALB/c female mice treated with 7-12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cystine; Female; Glutathione Peroxidase; Liver; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organoselenium Compounds; Selenic Acid; Selenious Acid; Selenium; Selenium Compounds; Selenomethionine | 1990 |
Radioiodinated ligands for the estrogen receptor: tissue distribution of 17 alpha-[125I]iodovinylestradiol derivatives in normal and tumor-bearing adult female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma 256, Walker; Estradiol; Female; Iodine Radioisotopes; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tissue Distribution | 1990 |
A mammary stimulating mitogen(s) from rat muscle: its possible influence in mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abdomen; Animals; Cell Division; Cells, Cultured; Female; Growth Substances; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Muscles; Rats; Rats, Inbred Strains; Tissue Extracts | 1990 |
Effects of high dietary fat on the total DNA and receptor contents in rats with 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Bromodeoxyuridine; Cell Division; Dietary Fats; DNA, Neoplasm; Female; Flow Cytometry; Kinetics; Mammary Neoplasms, Experimental; Rats; Receptors, Estrogen; Receptors, Progesterone | 1990 |
Human chorionic gonadotropin and rat mammary cancer prevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Chorionic Gonadotropin; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1990 |
Quantitative assessment of fat and calorie as risk factors in mammary carcinogenesis in an experimental model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diet, Reducing; Dietary Fats; Disease Models, Animal; Energy Intake; Female; Linoleic Acids; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Risk Factors | 1990 |
Protective effect of chorionic gonadotropin on DMBA-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Chorionic Gonadotropin; Endocrine Glands; Estrus; Female; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1990 |
Activation of H-ras oncogenes in preneoplastic mouse mammary tissues.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mutation; Polymerase Chain Reaction; Precancerous Conditions | 1990 |
Genetic instability and the acquisition of metastatic ability by rat mammary cancer cells following v-H-ras oncogene transfection.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Chromosome Aberrations; Chromosome Disorders; DNA, Neoplasm; Female; Genes, ras; Karyotyping; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Metastasis; Ploidies; Rats; Rats, Inbred Strains; Transfection | 1990 |
Modulatory influences of tamoxifen, tocopherol, retinyl acetate, aminoglutethimide, ergocryptine and selenium on DMBA-induced initiation of mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Animals; Diterpenes; Drug Interactions; Ergolines; Female; Mammary Neoplasms, Experimental; Rats; Retinyl Esters; Selenium; Tamoxifen; Vitamin A; Vitamin E | 1990 |
Site of expression and biological function of the rat mammary carcinoma suppressor gene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Crosses, Genetic; Female; Genes, Dominant; Genes, Suppressor; Mammary Neoplasms, Experimental; Rats; Rats, Inbred F344; Rats, Inbred Strains; Rats, Inbred WF; Time Factors | 1990 |
Effect of human chorionic gonadotropin on mammary gland differentiation and carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Body Weight; Cell Differentiation; Chorionic Gonadotropin; DNA Replication; Estrus; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Organ Size; Rats; Rats, Inbred Strains; Uterus | 1990 |
Effect of miso (Japanese soybean paste) and NaCl on DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Female; Food, Fortified; Glycine max; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Sodium Chloride | 1990 |
Mammary tumor lipids and plasma lipoproteins in DMBA-intubated rats fed olive or safflower oils.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Dietary Fats, Unsaturated; Female; Intubation; Lipid Metabolism; Lipoproteins; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Olive Oil; Plant Oils; Rats; Rats, Inbred Strains; Safflower Oil | 1990 |
Antiestrogen-binding sites in 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors: relation to growth.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen | 1990 |
Mammary tumor immunoscintigraphy in rats: the use of 131I-anti-estriol 3-sulfate antibody.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies; Estriol; Female; Goats; Guinea Pigs; Immunoglobulin G; Iodine Radioisotopes; Mammary Neoplasms, Experimental; Radionuclide Imaging; Rats; Rats, Inbred Strains; Tissue Distribution | 1990 |
[Effect of high dietary fat on the total DNA and receptor contents in rats with 7,12-dimethylbenz[A]anthracene-induced mammary carcinoma].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; DNA, Neoplasm; Female; Flow Cytometry; Mammary Neoplasms, Experimental; Ploidies; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; S Phase | 1990 |
Steady-state mRNA expression for growth factors in DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Blotting, Northern; DNA Probes; ErbB Receptors; Female; Growth Substances; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Nucleic Acid Hybridization; Phosphorylation; Rats; Rats, Inbred Strains; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor alpha | 1990 |
Chemoprevention of 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in rat by the combined actions of selenium, magnesium, ascorbic acid and retinyl acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Body Weight; Diterpenes; Drug Administration Schedule; Female; Magnesium Chloride; Mammary Neoplasms, Experimental; Rats; Retinyl Esters; Selenic Acid; Selenium; Selenium Compounds; Vitamin A | 1990 |
Effect of the mammary carcinogen 7,12-dimethylbenz[a]anthracene on pineal melatonin biosynthesis, secretion and peripheral metabolism.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Circadian Rhythm; Estradiol; Female; Kinetics; Mammary Neoplasms, Experimental; Melatonin; Pineal Gland; Prolactin; Rats; Rats, Inbred Strains; Serotonin | 1990 |
Strain difference in neoplastic response to DMBA powder dusted onto mammary tissues between Wistar/Furth and Copenhagen strains of rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Female; Male; Mammary Neoplasms, Experimental; Powders; Rats; Rats, Inbred Strains; Sarcoma, Experimental; Sex Factors; Species Specificity | 1990 |
Amine oxidase activities in chemically-induced mammary cancer in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amine Oxidase (Copper-Containing); Animals; Clorgyline; Female; Fibroma; Kinetics; Mammary Neoplasms, Experimental; Monoamine Oxidase; Rats; Rats, Inbred Strains | 1990 |
Chemoendocrine therapy in DMBA-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1990 |
Estrogen and progesterone receptor levels in 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors in each week--check points about experimental studies using DMBA-induced tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone | 1990 |
Enhancement of mammary carcinogenesis by high levels of dietary fat: a phenomenon dependent on ad libitum feeding.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Eating; Energy Intake; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Weight Gain | 1990 |
Antineoplastic properties of Maharishi-4 against DMBA-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; beta-Endorphin; Enkephalin, Methionine; Estradiol; Female; Hypothalamus; Mammary Neoplasms, Experimental; Medicine, Ayurvedic; Pituitary Gland; Plants, Medicinal; Prolactin; Rats; Rats, Inbred Strains | 1990 |
Antiestrogenic and antitumor properties of the new triphenylethylene derivative toremifene in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen; Toremifene; Uterus | 1990 |
Antitumor effects of combination toremifene and medroxyprogesterone acetate (MPA) in vitro and in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Estrogen Antagonists; Female; Humans; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Ovarian Neoplasms; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Toremifene; Tumor Cells, Cultured | 1990 |
Effect of CGS 16949A plus tamoxifen on induced mammary tumours in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrone; Fadrozole; Female; Follicle Stimulating Hormone; Imidazoles; Luteinizing Hormone; Mammary Neoplasms, Experimental; Nitriles; Prolactin; Rats; Rats, Inbred Strains; Tamoxifen | 1990 |
Biochemical and pharmacological effects of toremifene metabolites.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cell Division; Mammary Neoplasms, Experimental; Mice; Rats; Receptors, Estrogen; Tamoxifen; Toremifene; Tumor Cells, Cultured | 1990 |
Effects of sequential and combined endocrine therapies on the growth of 7,12-dimethylbenz [alpha] anthracene-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Ovariectomy; Rats; Rats, Inbred Strains; Tamoxifen | 1990 |
Expression of the retrotransposons, intracisternal A-particles, during neoplastic progression of mouse mammary epithelium analyzed with a monoclonal antibody.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Monoclonal; Blotting, Western; Cell Line; Cells, Cultured; DNA Transposable Elements; Epithelial Cells; Female; Fluorescent Antibody Technique; Gene Expression; Genes, Intracisternal A-Particle; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Proto-Oncogenes; Reference Values | 1990 |
Eicosanoid synthesis and ornithine decarboxylase activity in mammary tumors of rats fed varying levels and types of N-3 and/or N-6 fatty acids.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dietary Fats; Eicosanoids; Fatty Acids; Female; gamma-Linolenic Acid; Linolenic Acids; Mammary Neoplasms, Experimental; Ornithine Decarboxylase; Plant Oils; Rats; Rats, Inbred Strains | 1990 |
Dedifferentiation of rat mammary myoepithelial-like cell lines after passage in vivo or cloning in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Cell Differentiation; Clone Cells; Collagen; Epithelium; Female; Fluorescent Antibody Technique; Histocytochemistry; Keratins; Laminin; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Microscopy, Electron; Phenotype; Rats; Rats, Inbred Strains; Staining and Labeling; Vimentin | 1986 |
Immediate ascites conversion of mammary tumors induced in NYLR/Nya mice by 7,12-dimethylbenz-[a] anthracene and urethane feeding and by forced breeding.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Ascites; Breeding; Carcinoma; Cell Division; Cell Line; Chromosomes; Female; Karyotyping; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Microscopy, Electron; Staining and Labeling; Urethane | 1986 |
Chemoprevention of 7,12-dimethylbenz(alpha)anthracene (DMBA) induced rat mammary tumors by 2-amino-5-bromo-6-phenyl-4(3H)-pyrimidinone (ABPP).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cytosine; Female; Interferons; Mammary Neoplasms, Experimental; Organ Size; Rats; Rats, Inbred Strains | 1986 |
Interspecies comparison of human and rat mammary epithelial cell-mediated mutagenesis by polycyclic aromatic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Biotransformation; Breast; Breast Neoplasms; Carcinogens; Cells, Cultured; Epithelium; Female; Humans; Keratins; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mutation; Polycyclic Compounds; Rats; Rats, Inbred Strains; Species Specificity | 1986 |
[Antitumor activity of peplomycin against 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bleomycin; Doxorubicin; Female; Mammary Neoplasms, Experimental; Peplomycin; Rats; Rats, Inbred Strains | 1987 |
Immunohistochemical studies of DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Chondroitin Sulfates; Collagen; Female; Fibronectins; Glycosaminoglycans; Keratins; Laminin; Lectins; Mammary Neoplasms, Experimental; Mucins; Myosins; Rats | 1988 |
Angiogenic activity of rat mammary carcinomas induced by 7,12-dimethylbenz[a]anthracene and its inhibition by medroxyprogesterone acetate: possible involvement of antiangiogenic action of medroxyprogesterone acetate in its tumor growth inhibition.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cells, Cultured; Drug Interactions; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Neovascularization, Pathologic; Rats; Rats, Inbred Strains | 1988 |
A new irreversible aromatase inhibitor, 6-methylenandrosta-1,4-diene-3,17-dione (FCE 24304): antitumor activity and endocrine effects in rats with DMBA-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstadienes; Animals; Aromatase; Aromatase Inhibitors; Endocrine Glands; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Organ Size; Ovary; Prolactin; Rats; Rats, Inbred Strains | 1989 |
Fate of 7,12-dimethylbenz(a)anthracene in the mouse mammary gland during initiation and promotion stages of carcinogenesis in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biological Transport; Carbon Radioisotopes; Cell Transformation, Neoplastic; DNA; DNA Damage; Female; Kinetics; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Organ Culture Techniques; Protein Biosynthesis | 1989 |
Effects of host hormonal status on binding of activated estrogen receptor to nuclei from R3230AC and 7,12-dimethylbenz[a]anthracene-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Female; Gonadal Steroid Hormones; Mammary Neoplasms, Experimental; Ovariectomy; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Estrogen | 1989 |
Determination of degree of energy restriction necessary to reduce DMBA-induced mammary tumorigenesis in rats during the promotion phase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adipose Tissue; Animals; Blood Glucose; Body Composition; Body Weight; Energy Intake; Female; Insulin; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1989 |
Effect of dietary palm oils on mammary carcinogenesis in female rats induced by 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carotenoids; Cocarcinogenesis; Dietary Fats, Unsaturated; Fatty Acids; Female; Lipids; Mammary Neoplasms, Experimental; Palm Oil; Plant Oils; Rats; Rats, Inbred Strains | 1989 |
Effect of type and amount of dietary fat on the enhancement of rat mammary tumorigenesis by exercise.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adipose Tissue; Animals; Dietary Fats; Female; Mammary Neoplasms, Experimental; Physical Exertion; Rats; Rats, Inbred Strains | 1989 |
Phenotypic variability of chemically induced primary rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Phenotype; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Receptors, Estrogen; Sarcoma, Experimental | 1989 |
Androstenedione and androst-5-ene-3 beta,17 beta-diol stimulate DMBA-induced rat mammary tumors--role of aromatase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Androstenediol; Androstenediols; Androstenedione; Animals; Aromatase; Female; Flutamide; Mammary Neoplasms, Experimental; Ovariectomy; Rats; Rats, Inbred Strains; Silicone Elastomers | 1989 |
Histopathologic features of DMBA-induced mammary tumors in blind-underfed, blind-anosmic, and blind cold-exposed rats: influence of the pineal gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Blindness; Cold Temperature; Fasting; Female; Histocytochemistry; Mammary Neoplasms, Experimental; Olfaction Disorders; Pineal Gland; Rats; Rats, Inbred Strains | 1989 |
Effect of dietary brussels sprouts with increased selenium content on mammary carcinogenesis in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Diet; Female; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenium; Vegetables | 1989 |
Antitumor activity of the progesterone antagonists ZK 98.299 and RU 38.486 in the hormone-dependent MXT mammary tumor model of the mouse and the DMBA- and the MNU-induced mammary tumor models of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estrenes; Female; Gonanes; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mifepristone; Neoplasms, Hormone-Dependent; Progesterone; Rats; Rats, Inbred Strains | 1989 |
Inhibition of DMBA-induced mammary tumorigenesis by caloric restriction in rats fed high-fat diets.
Topics: 3-Hydroxybutyric Acid; 9,10-Dimethyl-1,2-benzanthracene; Animals; Blood Glucose; Diet, Reducing; Dietary Fats; Female; Hydroxybutyrates; Insulin; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1989 |
Effects of dietary selenium on DMBA-induced carcinogenesis in rats fed a diet high in mixed fats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Diet; Dietary Fats; Erythrocytes; Female; Glutathione Peroxidase; Lipid Peroxides; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenium | 1989 |
Changes in selenium and antioxidant status during DMBA-induced mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diet; Erythrocytes; Female; Glutathione Peroxidase; Liver; Malondialdehyde; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenium; Spleen; Superoxide Dismutase | 1989 |
New approaches to cancer chemoprevention with difluoromethylornithine and selenite.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Diet; Eflornithine; Female; Liver; Mammary Neoplasms, Experimental; Methionine; Ornithine Decarboxylase Inhibitors; Rats; Rats, Inbred Strains; Selenious Acid; Selenium | 1989 |
Correlation of estrogen, progesterone, and androgen receptors in breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Receptors, Androgen; Receptors, Estrogen; Receptors, Progesterone | 1989 |
Influence of 1 alpha,25-dihydroxyvitamin D3 on the development and steroid hormone receptor contents of DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Calcitriol; Calcium; Female; Mammary Neoplasms, Experimental; Ovary; Phosphorus; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone | 1989 |
Caloric restriction and 7,12-dimethylbenz(a)anthracene-induced mammary tumor growth in rats: alterations in circulating insulin, insulin-like growth factors I and II, and epidermal growth factor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Energy Intake; Epidermal Growth Factor; Female; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Mammary Neoplasms, Experimental; Prolactin; Rats; Rats, Inbred Strains; Somatomedins | 1989 |
Growth factor binding to 7,12-dimethylbenz(a)anthracene-induced mammary tumors from rats subject to chronic caloric restriction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Energy Intake; Epidermal Growth Factor; Female; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Somatomedins | 1989 |
A comparison of the effects of the prostaglandin synthesis inhibitors indomethacin and carprofen on 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis in rats fed different amounts of essential fatty acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cell Transformation, Neoplastic; Dietary Fats; Fatty Acids, Essential; Female; Indomethacin; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Prostaglandin Antagonists; Prostaglandins E; Rats; Rats, Inbred Strains | 1989 |
[Mechanism of the stimulating effect of estradiol on protein kinase C in plasma membranes of target cells].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Membrane; Enzyme Activation; Estradiol; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Protein Kinase C; Rats; Rats, Inbred Strains | 1989 |
Transcriptional down-regulation of a rat gene, WDNM2, in metastatic DMBA-8 cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Base Sequence; Blotting, Southern; DNA, Circular; DNA, Neoplasm; Female; Gene Amplification; Mammary Neoplasms, Experimental; Molecular Sequence Data; Neoplasm Metastasis; Nucleic Acid Hybridization; Phenotype; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Neoplasm; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Induction of mixed function oxidase activities of protein A in rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaline Phosphatase; Animals; Biomarkers, Tumor; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzyme Induction; Female; Glutathione; Glutathione Transferase; Mammary Neoplasms, Experimental; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Reference Values; Staphylococcal Protein A | 1989 |
Response of mammary tumors to caloric restriction for different time periods during the promotion phase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Energy Intake; Female; Humans; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Effects of trilostane on 7,12-dimethylbenz[a]anthracene-induced rat mammary cancers and body weight of rats in relation to estrogen receptors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Dihydrotestosterone; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen | 1989 |
[Anti-carcinogenic and anti-blastic effect of vitamin A in various modes of its administration to random-bred rats during carcinogenesis of the mammary gland, induced by 7,12-dimethylbenz(a)anthracene].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Drug Administration Routes; Female; Mammary Neoplasms, Experimental; Rats; Vitamin A | 1989 |
Effects of dietary fat, calcium, and vitamin D on growth and mammary tumorigenesis induced by 7,12-dimethylbenz(a)anthracene in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Calcium, Dietary; Dietary Fats, Unsaturated; Female; Mammary Neoplasms, Experimental; Plant Oils; Rats; Rats, Inbred Strains; Sunflower Oil; Vitamin D | 1989 |
Inhibition of rat mammary carcinogenesis by monoterpenoids.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acyclic Monoterpenes; Animals; Cyclohexenes; Limonene; Mammary Neoplasms, Experimental; Menthol; Monoterpenes; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Terpenes | 1989 |
Imaging of rats with mammary cancer with two 2-deoxy-2-[18F]fluoro-D-hexoses.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Deoxyglucose; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Fucose; Galactose; Mammary Neoplasms, Experimental; Radionuclide Imaging; Rats; Rats, Inbred Strains | 1989 |
[Effects of chemo-endocrine therapy on DMBA-induced rat mammary carcinoma].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1989 |
Effect of the irreversible aromatase inhibitor FCE 24304 on DMBA-induced mammary tumors in ovariectomized rats treated with testosterone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstadienes; Animals; Antineoplastic Agents; Aromatase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Mammary Neoplasms, Experimental; Ovariectomy; Ovary; Rats; Rats, Inbred Strains; Testosterone | 1989 |
Hormone prevention of mammary carcinogenesis by norethynodrel-mestranol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Age Factors; Animals; Body Weight; Contraceptives, Oral, Combined; Disease Susceptibility; DNA; Dose-Response Relationship, Drug; Estrus; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mestranol; Norethynodrel; Rats; Rats, Inbred Strains | 1989 |
Intrinsic differences in the transplantability and outgrowth potential of DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Cell Division; Estrogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Ovariectomy; Parity; Progesterone; Rats; Rats, Inbred Lew | 1989 |
[Estrogen dependent plasminogen activator in breast cancer cells; experimental and clinical studies].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Breast Neoplasms; Clinical Enzyme Tests; Estradiol; Estrogen Antagonists; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Ovariectomy; Plasminogen Activators; Rats; Receptors, Estrogen; Tumor Cells, Cultured | 1989 |
Antitumor activity of the antiprogestins ZK 98.299 and RU 38.486 in hormone dependent rat and mouse mammary tumors: mechanistic studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Gonanes; Mammary Neoplasms, Experimental; Methylnitrosourea; Mifepristone; Neoplasm Transplantation; Organ Size; Ovariectomy; Ovary; Rats; Rats, Inbred Strains; Uterus; Vagina | 1989 |
Inhibitory effect of androgens on DMBA-induced mammary carcinoma in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dihydrotestosterone; Drug Implants; Estradiol; Female; Flutamide; Mammary Neoplasms, Experimental; Organ Size; Ovariectomy; Rats; Rats, Inbred Strains; Uterus | 1989 |
The effect of the aromatase inhibitor, 4-(phenylthio)-4-androstene-3,17-dione, on dimethylbenz(A)anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1989 |
Aromatase inhibition and experimental antitumor activity of FCE 24304, MDL 18962 and SH 489.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstadienes; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Female; Humans; Luteinizing Hormone; Male; Mammary Neoplasms, Experimental; Microsomes; Orchiectomy; Ovary; Pargyline; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Reference Values | 1989 |
The effect of pregnant mares serum gonadotrophin on the response of DMBA induced rat mammary tumours to tamoxifen or oestrogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diethylstilbestrol; Drug Interactions; Female; Gonadotropins, Equine; Mammary Neoplasms, Experimental; Ovariectomy; Rats; Rats, Inbred Strains; Tamoxifen | 1989 |
Lack of modifying effects of linolic acid hydroperoxides and their secondary oxidative products on combined 7,12-dimethylbenz[a]anthracene and 1,2-dimethylhydrazine-initiated mammary gland, ear duct and colon carcinogenesis in female Sprague-Dawley rats.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Colonic Neoplasms; Dimethylhydrazines; Ear Neoplasms; Female; Leukemia, Experimental; Linoleic Acids; Lipid Peroxides; Mammary Neoplasms, Experimental; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1989 |
Pineal gland in rats with 7,12-dimethylbenz(a)anthracene-induced mammary tumors subjected to manipulations known as enhancers of pineal actions.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blindness; Cold Temperature; Female; Mammary Neoplasms, Experimental; Nutrition Disorders; Olfaction Disorders; Olfactory Bulb; Pineal Gland; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1989 |
Sequential hormone therapy with medroxyprogesterone acetate for 7, 12-dimethylbenz [alpha] anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Therapy, Combination; Estradiol; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1989 |
Effect of medroxyprogesterone acetate on the response of the rat mammary gland to carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Drug Administration Schedule; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Rats, Inbred Strains; Weight Gain | 1989 |
In vivo assessment of 111In-labeled hematoporphyrin derivative in breast tumor-bearing animals.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Female; Hematoporphyrin Derivative; Hematoporphyrins; Indium Radioisotopes; Mammary Neoplasms, Experimental; Mice; Radionuclide Imaging; Rats; Rats, Inbred Strains; Tissue Distribution | 1989 |
Additive inhibitory effects of bromocryptine (CB-154) and medroxyprogesterone acetate (MPA) on dimethylbenz[a]anthracene (DMBA)-induced mammary tumors in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Bromocriptine; Drug Synergism; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone | 1989 |
Biodistribution and scintigraphy of 11C-toremifene in rats bearing DMBA-induced mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chemical Phenomena; Chemistry; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Rats; Tamoxifen; Tissue Distribution; Tomography, Emission-Computed; Toremifene | 1989 |
Endocrine and antitumor effects of combined treatment with an antiprogestin and antiestrogen or luteinizing hormone-releasing hormone agonist in female rats bearing mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Buserelin; Cytosol; Drug Implants; Estrenes; Female; Follicle Stimulating Hormone; Goserelin; Injections, Subcutaneous; Luteinizing Hormone; Mammary Neoplasms, Experimental; Mifepristone; Progestins; Rats; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1989 |
Chemotherapeutic evaluation of glucarate and N-(4-hydroxyphenyl)retinamide alone and in combination in the rat mammary tumor model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Female; Fenretinide; Glucaric Acid; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tretinoin | 1989 |
Antitumor effect of a specific aromatase inhibitor, 1-methyl-androsta-1,4-diene-3,17-dione (atamestane), in female rats bearing DMBA-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Fadrozole; Female; Imidazoles; Mammary Neoplasms, Experimental; Nitriles; Rats; Rats, Inbred Strains | 1989 |
Lability of steroid hormone receptors following devascularization of breast tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Half-Life; In Vitro Techniques; Ischemia; Mammary Neoplasms, Experimental; Rats; Receptors, Androgen; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Progesterone; Time Factors; Tissue Preservation | 1989 |
Effects of D,L-2-difluoromethylornithine and indomethacin on mammary tumor promotion in rats fed high n-3 and/or n-6 fat diets.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Eflornithine; Female; Indomethacin; Leukotriene B4; Mammary Neoplasms, Experimental; Ornithine Decarboxylase; Prostaglandins E; Rats; Rats, Inbred Strains | 1989 |
Chemoprevention of experimental mammary carcinogenesis by the synthetic organoselenium compound, benzylselenocyanate, in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cyanates; DNA; Female; Mammary Neoplasms, Experimental; Organoselenium Compounds; Rats; Rats, Inbred Strains; Selenium; Sodium Selenite; Thiocyanates | 1989 |
Tissue selenium levels in selenium-supplemented rats and their relevance in mammary cancer protection.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Glutathione Peroxidase; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenium; Selenomethionine; Sodium Selenite; Tissue Distribution | 1989 |
Beta-adrenergic receptors in DMBA-induced rat mammary tumors: correlation with progesterone receptor and tumor growth.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenergic beta-Antagonists; Aging; Animals; Catecholamines; Female; Hormones; Iodine Radioisotopes; Kinetics; Mammary Neoplasms, Experimental; Neoplasm Regression, Spontaneous; Neoplasms, Hormone-Dependent; Ovariectomy; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Progesterone; Substrate Specificity | 1989 |
Isolation and characterization of clonal cell lines from a transplantable metastasizing rat mammary tumor, TR2CL.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Female; Histocytochemistry; Keratins; Laminin; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Rats; Rats, Inbred F344 | 1985 |
Comparison of nuclear proteins from DMBA-induced mammary tumors and lactating mammary glands by polyacrylamide gel electrophoresis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; DNA; Electrophoresis, Polyacrylamide Gel; Female; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Nucleoproteins; Pregnancy; Rats; Rats, Inbred Strains; RNA | 1985 |
Immunological identity of a 60 kd oncofetal protein induced in rats by chemical carcinogens and released by transformed cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies; Antigens, Neoplasm; Carcinogens; Cell Transformation, Neoplastic; Epitopes; Female; Immunosorbent Techniques; Liver Neoplasms, Experimental; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Rats; Rats, Inbred BUF; Rats, Inbred Strains | 1985 |
Differential regulation of c-Ha-ras and c-Ki-ras gene expression in rat mammary gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Deoxyribonuclease HindIII; DNA Restriction Enzymes; Female; Gene Expression Regulation; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Oncogenes; Pregnancy; Rats; RNA, Neoplasm | 1987 |
[Endogenous MMTV in the normal mammary gland and in dimethylanthracene-induced mammary cancer in BALB/c mice].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Viral; Female; Genes, Viral; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Pregnancy; Viral Proteins | 1987 |
c-H-ras-1 expression in 7,12-dimethyl benzanthracene-induced Balb/c mouse mammary hyperplasias and their tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Codon; DNA; DNA, Viral; Female; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Mutation; Precancerous Conditions; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Proto-Oncogenes | 1988 |
Morphological and biological characteristics of mammary tumours induced by the direct application of DMBA powder to rat mammary glands.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenocarcinoma, Papillary; Animals; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Carcinosarcoma; Female; Male; Mammary Neoplasms, Experimental; Microscopy, Electron; Ovariectomy; Rats; Rats, Inbred Strains; Sarcoma, Experimental | 1988 |
Effect of 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis on the opioid peptide levels in the rat central nervous system.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Animals; beta-Endorphin; Brain; Corpus Striatum; Dynorphins; Endorphins; Enkephalin, Methionine; Female; Hypothalamus; Mammary Neoplasms, Experimental; Peptide Fragments; Pituitary Gland; Radioimmunoassay; Rats; Rats, Inbred Strains | 1986 |
Prolactin cells of female rats treated with the carcinogen 7,12-dimethylbenz(A) anthracene (DMBA) in vivo. An ultrastructural study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Mammary Neoplasms, Experimental; Pituitary Gland; Pituitary Neoplasms; Prolactin; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Inhibitory effect of an oxygenated cholesterol on the induction and progression of DMBA-induced mammary carcinomas in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Survival; Female; Hydroxycholesterols; Mammary Neoplasms, Experimental; Rats; Stereoisomerism | 1986 |
gamma-Glutamyltranspeptidase in dimethylbenz[a]anthracene-induced mammary adenocarcinomas and in livers of tumor bearing rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Female; gamma-Glutamyltransferase; Kinetics; Lactation; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Pregnancy; Rats; Rats, Inbred Strains | 1987 |
Effective sequential administration of tamoxifen and medroxyprogesterone acetate for 7,12-dimethylbenz[a-anthracene-induced rat mammary tumors in relation to hormone receptors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Administration Schedule; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Time Factors | 1985 |
[Combined therapies with medroxyprogesterone acetate (MPA) in DMBA-induced rat mammary cancer].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Estrogens; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Rats, Inbred Strains; Tegafur | 1986 |
Effect of hematoporphyrin derivative on estrogen receptors in the dimethylbenzanthracene-mammary tumor model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Hematoporphyrin Derivative; Hematoporphyrin Photoradiation; Hematoporphyrins; Mammary Neoplasms, Experimental; Photochemotherapy; Rats; Rats, Inbred Strains; Receptors, Estrogen | 1987 |
Adrenal steroids stimulate growth and progesterone receptor levels in rat uterus and DMBA-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex Hormones; Androstenediol; Androstenedione; Animals; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Mammary Neoplasms, Experimental; Ovariectomy; Promegestone; Rats; Rats, Inbred Strains; Receptors, Progesterone; Uterus | 1986 |
Effect of hematoporphyrin derivative 2 on estrogen receptors in experimental mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; Hematoporphyrin Derivative; Hematoporphyrin Photoradiation; Hematoporphyrins; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen | 1987 |
Effect of n-3 fatty acids on mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats, Unsaturated; Fatty Acids, Unsaturated; Female; Fish Oils; In Vitro Techniques; Lymphocyte Activation; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1987 |
CGS 16949A, a new nonsteroidal aromatase inhibitor: effects on hormone-dependent and -independent tumors in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Animals; Aromatase Inhibitors; Body Weight; Cell Line; Drug Screening Assays, Antitumor; Fadrozole; Female; Imidazoles; Mammary Neoplasms, Experimental; Nitriles; Rats; Tamoxifen | 1988 |
Inhibition of rat mammary carcinogenesis by an arotinoid without a polar end group (Ro 15-0778).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Dose-Response Relationship, Drug; Female; Fenretinide; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Retinoids; Time Factors; Tretinoin | 1987 |
Putative metabolites derived from dietary combinations of calcium glucarate and N-(4-hydroxyphenyl)retinamide act synergistically to inhibit the induction of rat mammary tumors by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Diet; Drug Synergism; Fenretinide; Glucaric Acid; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Sugar Acids; Tretinoin | 1988 |
[The activity of nonspecific bone marrow and spleen suppressors in the latent period of tumor growth].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antibody-Producing Cells; Bone Marrow; Bone Marrow Transplantation; Female; Fibrosarcoma; Immunization, Passive; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred A; Mice, Inbred C57BL; Spleen; T-Lymphocytes, Regulatory; Transplantation, Isogeneic | 1988 |
Expression of the c-Ha-ras and neu oncogenes in DMBA-induced, anti-estrogen-treated rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Deoxyribonucleases, Type II Site-Specific; DNA, Neoplasm; Estrogen Antagonists; Gene Expression Regulation; Genes, ras; Mammary Neoplasms, Experimental; Oncogenes; Rats; Rats, Inbred Strains; RNA, Neoplasm; Tamoxifen; Toremifene | 1988 |
Antitumor actions of toremifene in the 7,12-dimethylbenzanthracene (DMBA)-induced rat mammary tumor model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estrogen Antagonists; Mammary Neoplasms, Experimental; Progesterone; Rats; Rats, Inbred Strains; Tamoxifen; Toremifene | 1988 |
[Participation of the adenyl cyclase system in estradiol-activated growth of tumors in rat mammary glands].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 9,10-Dimethyl-1,2-benzanthracene; Adenylyl Cyclases; Animals; Cell Division; Cyclic AMP; Enzyme Activation; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Uterus | 1985 |
[Nuclear magnetic resonance investigations of DMBA-induced rat breast cancers--the relationship between tumor doubling times and water proton spin-lattice relaxation times].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Water; Cell Division; Estradiol; Female; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Protons; Rats; Rats, Inbred Strains; Receptors, Estrogen | 1985 |
Membranal tyrosine protein kinase activity (but not cAMP-dependent protein kinase activity) is associated with growth of rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiotensin II; Animals; Cell Division; Cyclic AMP; Female; Mammary Neoplasms, Experimental; Membranes; Oligopeptides; Perphenazine; Prolactin; Protein Kinases; Protein-Tyrosine Kinases; Quercetin; Rats | 1985 |
Phosphoinositide phosphorylation precedes growth in rat mammary tumors.
Topics: 1-Phosphatidylinositol 4-Kinase; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cyclic AMP; Female; Mammary Neoplasms, Experimental; Membranes; Phosphatidylinositols; Phosphorylation; Phosphotransferases; Protein-Tyrosine Kinases; Quercetin; Rats | 1986 |
Cyclic nucleotide levels in human breast cancer and in rat mammary tissues during tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenofibroma; Animals; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cyclic AMP; Cyclic GMP; DNA, Neoplasm; Female; Fibrocystic Breast Disease; Humans; Mammary Neoplasms, Experimental; Prognosis; Rats; Rats, Inbred Strains | 1985 |
Influence of alkyl-chain fluorination on the action of mammary tumor inhibiting 2,3-bis(hydroxyphenyl)butanes and 2,3-bis(hydroxyphenyl)but-2-enes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Binding, Competitive; Cattle; Estrogen Antagonists; Estrogens, Non-Steroidal; Female; Fluorine; Hexestrol; In Vitro Techniques; Mammary Neoplasms, Experimental; Mice; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Receptors, Estradiol; Structure-Activity Relationship; Uterus | 1986 |
Anticarcinogenic effect of retinoids on 7,12-dimethylbenz(a)anthracene-induced mammary tumor induction, and its relationship to cyclic AMP-dependent protein kinase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cyclic AMP; Female; Mammary Neoplasms, Experimental; Protamine Kinase; Protein Kinases; Rats; Retinoids | 1986 |
[The status of steroid receptors and hormone response in 7,12-dimethylbenz (a) anthracene (DMBA) induced rat mammary tumor].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Receptors, Steroid | 1985 |
Mammary tumors in feral mice lacking MuMTV DNA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Cell Transformation, Neoplastic; Collodion; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Genes, Viral; Liver; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Muridae; Paper; Spleen | 1985 |
Mammary preneoplasia and tumorigenesis in the BALB/c mouse: structure and modification of mouse mammary tumor virus DNA sequences.
Topics: 5-Methylcytosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cytosine; DNA Restriction Enzymes; DNA, Viral; Female; Genes, Viral; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methylation; Mice; Mice, Inbred BALB C; Precancerous Conditions; Recombination, Genetic; Virus Replication | 1987 |
Characterization of the cyclic adenosine 3':5'-monophosphate effector system in hormone-dependent and hormone-independent rat mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Cyclic AMP; Female; Macromolecular Substances; Mammary Neoplasms, Experimental; Molecular Weight; Phosphorylation; Protein Kinases; Rabbits; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1987 |
Biochemical alterations in 7,12-dimethylbenz[a]anthracene-induced mammary tumors from rats subjected to caloric restriction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Dietary Carbohydrates; Energy Intake; Female; Fructose-Bisphosphatase; Glucosephosphate Dehydrogenase; Hexokinase; L-Lactate Dehydrogenase; Liver; Malate Dehydrogenase; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Pyruvate Kinase; Rats; Rats, Inbred Strains | 1987 |
Activation of endogenous MMTV proviruses in murine mammary cancer induced by chemical carcinogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Line; DNA, Viral; Female; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methylation; Mice; Mice, Inbred BALB C; Proto-Oncogenes; Repetitive Sequences, Nucleic Acid; Retroviridae Proteins; RNA, Viral; Virus Activation | 1987 |
Enhancement of tumorigenicity with morphological progression in a BALB/c preneoplastic outgrowth line.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Ovariectomy; Precancerous Conditions | 1987 |
Effects of high dietary fat on the growth and development of ovarian-independent carcinogen-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Dietary Fats; Estrogens; Female; Mammary Neoplasms, Experimental; Ovariectomy; Ovary; Prolactin; Rats; Tamoxifen | 1986 |
Analysis of the risk reduction of prophylactic partial mastectomy in Sprague-Dawley rats with 7,12-dimethylbenzanthracene-induced breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Mastectomy; Rats; Rats, Inbred Strains; Risk; Time Factors | 1986 |
Protection by the alkyllysophospholipid, 1-octadecyl-2-methoxy-rac-glycero-3-phosphocholine, but not by the retinoid etretinate against leukemia development in DMBA-treated Long-Evans rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Etretinate; Female; Leukemia, Experimental; Lysophosphatidylcholines; Lysophospholipids; Male; Mammary Neoplasms, Experimental; Phospholipid Ethers; Phospholipids; Rats | 1986 |
Inheritance and site of expression of genes controlling susceptibility to mammary cancer in an inbred rat model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Gene Expression Regulation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mosaicism; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Regression of rat primary mammary tumors following dietary d-limonene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cyclohexenes; Female; Limonene; Mammary Neoplasms, Experimental; Palpation; Rats; Rats, Inbred Strains; Terpenes; Time Factors | 1986 |
Net energy effects of dietary fat on chemically induced mammary carcinogenesis in F344 rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Composition; Body Weight; Cocarcinogenesis; Dietary Fats; Energy Intake; Energy Metabolism; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred F344; Time Factors | 1986 |
Influence of dietary retinyl acetate on normal rat mammary gland development and on the enhancement of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumorigenesis by high levels of dietary fat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Cocarcinogenesis; Dietary Fats; Diterpenes; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Retinoids; Retinyl Esters; Time Factors; Vitamin A | 1986 |
Phospholipase C activity in normal rat mammary tissues and in DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Pregnancy; Rats; Rats, Inbred Strains; Type C Phospholipases | 1986 |
Effect of dietary polyunsaturated fat and 7,12-dimethylbenz(a)-anthracene on rat splenic natural killer cells and prostaglandin E synthesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Fatty Acids, Unsaturated; Female; Killer Cells, Natural; Mammary Neoplasms, Experimental; Prostaglandins E; Rats; Spleen | 1986 |
[Estradiol and progesterone receptors in DMBA-induced mammary neoplasms in rats under cyclic hormonal exposures].
Topics: 17-alpha-Hydroxyprogesterone; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cytosol; Female; Hydroxyprogesterones; Mammary Neoplasms, Experimental; Rats; Receptors, Estradiol; Receptors, Estrogen; Receptors, Progesterone; Testosterone; Time Factors | 1986 |
Inhibition of chemically induced mammary carcinogenesis in rats by long-term exposure to butylated hydroxytoluene (BHT): interrelations among BHT concentration, carcinogen dose, and diet.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actuarial Analysis; Adrenal Cortex; Animals; Body Weight; Butylated Hydroxytoluene; Diet; Dose-Response Relationship, Drug; Eating; Female; Mammary Neoplasms, Experimental; Rats | 1986 |
BCG-modulated mammary carcinogenesis is dependent on the schedule of immunization but is not affected by dietary fat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; BCG Vaccine; Dietary Fats; Female; Killer Cells, Natural; Lymphocyte Activation; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Spleen | 1986 |
[Activation of protein kinase by estradiol in plasma membranes of estradiol-dependent tumors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Estradiol; Mammary Neoplasms, Experimental; Membrane Proteins; Neoplasms, Hormone-Dependent; Phosphorylation; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
Induction and growth of mammary tumors after superior cervical ganglionectomy in sighted and blinded-anosmic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylserotonin O-Methyltransferase; Animals; Female; Hypothalamus; Mammary Neoplasms, Experimental; Melatonin; Olfaction Disorders; Pineal Gland; Rats; Rats, Inbred Strains; Sensory Deprivation; Stress, Physiological; Sympathectomy; Vision, Ocular | 1986 |
Vascular reactivity to norepinephrine of 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors and normal tissue as studied in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Norepinephrine; Perfusion; Rats; Regional Blood Flow; Vascular Resistance; Vasomotor System | 1986 |
Effect of moderate vitamin A supplementation and lack of dietary vitamin A on the development of mammary tumors in female rats treated with low carcinogenic dose levels of 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Body Weight; Dose-Response Relationship, Drug; Female; Liver; Mammary Neoplasms, Experimental; Rats; Vitamin A; Vitamin A Deficiency | 1986 |
Calories, fat and cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Colonic Neoplasms; Diet; Diet, Reducing; Dietary Fats; Energy Intake; Female; Male; Mammary Neoplasms, Experimental; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1986 |
Mammary tumorigenesis in rats fed diets high in lard.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Dietary polyunsaturated fat in relation to mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Coconut Oil; Corn Oil; Dietary Fats; Fatty Acids; Fatty Acids, Unsaturated; Female; Fish Oils; Mammary Neoplasms, Experimental; Oils; Plant Oils; Rats; Rats, Inbred Strains; Sunflower Oil | 1986 |
Selenium and experimental cancer.
Topics: 1,2-Dimethylhydrazine; 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Cricetinae; Diet; Dimethylhydrazines; DNA; Drug Interactions; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Rats; Selenium; Vitamin A; Vitamin E | 1986 |
Modification by antioxidants and p,p'-diaminodiphenylmethane of 7,12-dimethylbenz[a]anthracene-induced carcinogenesis of the mammary gland and ear duct in CD rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Ascorbic Acid; Bisacodyl; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Transformation, Neoplastic; Cresols; Diet; Ear Neoplasms; Ethoxyquin; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Vitamin E | 1986 |
Relationships between cellular superoxide dismutase and susceptibility to chemically induced cancer in the rat mammary gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Copper; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Manganese; Polycyclic Compounds; Pregnancy; Rats; Rats, Inbred Strains; Superoxide Dismutase | 1986 |
[Effect of vitamin A and hormones on the hormonal sensitivity of DMBA-induced mammary tumors in rats].
Topics: 17 alpha-Hydroxyprogesterone Caproate; 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Evaluation, Preclinical; Drug Therapy, Combination; Estrus; Female; Hormones; Hydroxyprogesterones; Insulin; Mammary Neoplasms, Experimental; Prednisolone; Rats; Testosterone; Time Factors; Vitamin A | 1986 |
An approach to the molecular mechanisms of cancer induction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Humans; Mammary Neoplasms, Experimental; Mice; Mutation; Neoplasms; Oncogenes; Papilloma; Skin Neoplasms; Transcription, Genetic | 1986 |
Interaction of vitamin C and selenium supplementation in the modification of mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ascorbic Acid; Dose-Response Relationship, Drug; Drug Interactions; Female; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenious Acid; Selenium; Selenomethionine | 1986 |
Combination chemoprevention of rat mammary carcinogenesis by indomethacin and butylated hydroxytoluene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Butylated Hydroxytoluene; Dose-Response Relationship, Drug; Female; Indomethacin; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1986 |
Genetic control of resistance to chemically induced mammary adenocarcinogenesis in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Alleles; Animals; Crosses, Genetic; Female; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Species Specificity | 1986 |
Dietary glucarate as anti-promoter of 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcium; Diet; Female; Glucaric Acid; Glucuronidase; Gonadal Steroid Hormones; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Sugar Acids | 1986 |
Anticarcinogenic and hepatotoxic interactions between retinyl acetate and butylated hydroxytoluene in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Butylated Hydroxytoluene; Diterpenes; Drug Administration Schedule; Female; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Retinyl Esters; Vitamin A | 1986 |
Effects of 12-O-tetradecanoylphorbol-13-acetate on carcinogen-induced mouse mammary lesions in organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Drug Synergism; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Tetradecanoylphorbol Acetate | 1986 |
[The effects of estradiol and prolactin on DMBA-induced mammary tumor in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Rats, Inbred Strains | 1986 |
Pathogenesis and characteristics of spontaneously metastasizing mammary carcinomas and the general principle of metastasis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antigens, Neoplasm; Antigens, Surface; Female; Immunization; Immunosuppression Therapy; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Methylcholanthrene; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Neoplastic Cells, Circulating; Organ Specificity; Rats; Rats, Inbred WF; Surface Properties | 1986 |
Quantitation of nuclear aberrations as a screen for agents damaging to mammary epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Nucleus; Epithelium; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mutagenicity Tests | 1986 |
Effect of D,L-2-difluoromethylornithine and endocrine manipulation on the induction of mammary carcinogenesis by 1-methyl-1-nitrosourea.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Eflornithine; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Polyamines; Rats; Rats, Inbred Strains; Tamoxifen | 1986 |
Inhibitory effects of the pineal hormone melatonin and underfeeding during the promotional phase of 7,12-dimethylbenzanthracene-(DMBA)-induced mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Cell Transformation, Neoplastic; Female; Food Deprivation; Mammary Neoplasms, Experimental; Melatonin; Prolactin; Rats; Rats, Inbred Strains | 1986 |
Polar solvents in the chemoprevention of dimethylbenzanthracene-induced rat mammary cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Dimethyl Sulfoxide; Diterpenes; Formamides; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Retinyl Esters; Solvents; Sulfones; Vitamin A | 1986 |
In vitro transformation of mouse mammary epithelial cells grown serum-free inside collagen gels.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blood Physiological Phenomena; Cell Transformation, Neoplastic; Cells, Cultured; Collagen; Epithelium; Female; Gels; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C | 1987 |
Effects of dietary protein, fat and energy intake during an initiation phase study of 7,12-dimethylbenz[a]anthracene-induced breast cancer in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Carcinogens; Dietary Fats; Dietary Proteins; Energy Intake; Female; Mammary Neoplasms, Experimental; Microsomes, Liver; Rats; Rats, Inbred Strains | 1986 |
[Ultrastructural study of rat mammary tumors and human breast cancer cells following treatment with tamoxifen].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Aged; Animals; Breast Neoplasms; Cell Nucleolus; Female; Humans; Mammary Neoplasms, Experimental; Microscopy, Electron; Middle Aged; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1986 |
Specific activation of the cellular Harvey-ras oncogene in dimethylbenzanthracene-induced mouse mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Mutation; Oncogenes; Polymorphism, Genetic | 1986 |
Cytochemical investigation of glucose-6-phosphate dehydrogenase activity in rat mammary tissue.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Glucosephosphate Dehydrogenase; Histocytochemistry; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Nitrogen; Oxygen; Pregnancy; Rats; Rats, Inbred Strains | 1987 |
Effects of estradiol and tamoxifen on creatine kinase in rodent mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenylate Kinase; Animals; Creatine Kinase; Estradiol; Female; Glucosephosphate Dehydrogenase; Isoenzymes; L-Lactate Dehydrogenase; Mammary Neoplasms, Experimental; Ovariectomy; Rats; Rats, Inbred Strains; Tamoxifen; Uterus | 1987 |
Selective induction of hormone-dependent mammary adenocarcinoma in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Age Factors; Animals; Female; Male; Mammary Neoplasms, Experimental; Methylcholanthrene; Neoplasms, Hormone-Dependent; Rats; Species Specificity | 1987 |
Normal but not carcinomatous primary rat mammary epithelium: readily transplanted to and maintained in the athymic nude mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Epithelium; Estrogens; Female; Graft Survival; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Perphenazine; Pituitary Neoplasms; Rats; Rats, Inbred Strains; Transplantation, Heterologous | 1987 |
Influence of chronic melatonin on 9,10-dimethyl-1,2-benzanthracene-induced mammary tumors in female Holtzman rats exposed to continuous light.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Light; Mammary Neoplasms, Experimental; Melatonin; Pineal Gland; Rats; Risk; Statistics as Topic | 1987 |
[Research related to hormones in Nagase analbuminemic rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Male; Mammary Neoplasms, Experimental; Pituitary Hormones, Anterior; Rats; Rats, Mutant Strains; Serum Albumin; Testosterone; Thyrotropin | 1987 |
Estrogen receptor binding to nuclei from normal and neoplastic rat mammary tissues in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Cell Nucleus; Deoxyribonuclease I; Female; Hydrogen-Ion Concentration; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Potassium Chloride; Pregnancy; Rats; Receptors, Estrogen | 1987 |
The effect of dietary seaweeds on 7,12-dimethyl-benz[a]anthracene-induced mammary tumorigenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Diet; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Seaweed; Sulfates | 1987 |
Characterization of the uptake of 16 alpha-([18F]fluoro)-17 beta-estradiol in DMBA-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biological Transport, Active; Blood Flow Velocity; Blood Volume; Estradiol; Female; Mammary Neoplasms, Experimental; Radioisotopes; Radionuclide Imaging; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tissue Distribution | 1987 |
Resistance to biological and chemical challenge in rodents treated with xerosin II, a natural product of Achromobacter xerosis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Achromobacter; Adjuvants, Immunologic; Animals; Anti-Bacterial Agents; Biological Assay; Endotoxins; Gram-Negative Aerobic Bacteria; Mammary Neoplasms, Experimental; Mice; Newcastle disease virus; Pneumonia; Rats | 1987 |
Enhanced in vitro proliferation and in vivo tumorigenic potential of mammary epithelium from BALB/c mice exposed in vivo to gamma-radiation and/or 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cells, Cultured; Epithelium; Female; Gamma Rays; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C | 1987 |
[Characteristics of the inhibition of thymus endocrine function and synthesis of substances with thymosin-like activity caused by thymostimulin and splenin during DMBA-induced mammary gland carcinogenesis in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Rats; Thymopoietins; Thymosin; Thymus Extracts; Thymus Gland; Thymus Hormones | 1987 |
Effect of submandibular gland removal on carcinogen induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Submandibular Gland | 1987 |
Stimulation of estradiol-17 beta secretion by 7,12-dimethylbenz (a) anthracene during mammary tumor induction in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androgens; Animals; Estradiol; Estrone; Estrus; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Proestrus; Progestins; Prolactin; Rats; Rats, Inbred Strains | 1987 |
Priming action on progesterone receptor synthesis by estradiol and tamoxifen in the 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1987 |
Cholestyramine promotes 7,12-dimethylbenzanthracene induced mammary cancer in Wistar rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Cholestyramine Resin; Cocarcinogenesis; Diet; Drug Synergism; Female; Lipids; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1987 |
Assessment of interaction among three carcinogens on rat mammary carcinogenesis in a factorially designed experiment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Cocarcinogenesis; Drug Synergism; Female; Mammary Neoplasms, Experimental; Procarbazine; Rats; Rats, Inbred Strains; Statistics as Topic; Time Factors; Whole-Body Irradiation | 1987 |
Importance of extended growth potential and growth factor independence on in vivo neoplastic potential of primary rat mammary carcinoma cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cholera Toxin; Epidermal Growth Factor; Female; Growth Substances; Insulin; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Lew | 1987 |
Reversal of the antitumor effects of tamoxifen by progesterone in the 7,12-dimethylbenzanthracene-induced rat mammary carcinoma model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Interactions; Estradiol; Estrenes; Estrogens; Estrone; Mammary Neoplasms, Experimental; Mifepristone; Organ Size; Progesterone; Rats; Tamoxifen | 1987 |
Analyses of two-way chronic studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Biometry; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Monte Carlo Method; Neoplasms; Species Specificity | 1987 |
Induction of mammary tumors in Wistar rats by intragastric intubation and by intramammary injection of 9-10 dimethyl-1-2 benzanthrancene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Freund's Adjuvant; Injections; Intubation, Gastrointestinal; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1987 |
Antimammary carcinogenic activity of 17-alpha-ethinyl estriol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Ethinyl Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Time Factors | 1987 |
Mammary cancer chemoprevention by inorganic and organic selenium: single agent treatment or in combination with vitamin E and their effects on in vitro immune functions.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Cytotoxicity, Immunologic; Female; Immune System; Killer Cells, Natural; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenious Acid; Selenium; Selenomethionine; Vitamin E | 1987 |
[Effect of correcting liver function on the development of DMBA-induced mammary gland tumors and the metabolism of sex steroid hormones in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Estradiol; Estriol; Female; Gonadal Steroid Hormones; Liver; Mammary Neoplasms, Experimental; Rats; Testosterone | 1987 |
Persistence of carcinogenic effect in intact progeny of mice treated transplacentally with 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Fetus; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Pregnancy; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Effects of subsequent antioxidant treatment on 7,12-dimethylbenz[a]anthracene-initiated carcinogenesis of the mammary gland, ear duct and forestomach in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Butylated Hydroxytoluene; Caffeic Acids; Ear Canal; Ear Neoplasms; Female; Guaiac; Hydroquinones; Mammary Neoplasms, Experimental; Propionates; Propyl Gallate; Quercetin; Rats; Rats, Inbred Strains; Stomach Neoplasms; Tetramethylphenylenediamine | 1988 |
Variability in response pattern of DMBA induced mammary tumors of Wistar rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Female; Mammary Neoplasms, Experimental; Neoplasm Regression, Spontaneous; Rats; Rats, Inbred Strains; Time Factors | 1987 |
Is the 7,12-dimethylbenz[a]anthracene-induced rat mammary tumor model suitable as a preclinical model to study mammary tumor malignancy?
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Neoplasm Metastasis; Neoplasm Recurrence, Local; Rats; Rats, Inbred Strains | 1987 |
Retinyl acetate inhibits estrogen-induced mammary carcinogenesis in female ACI rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Diterpenes; Eating; Ethinyl Estradiol; Female; Mammary Neoplasms, Experimental; Neoplasms, Multiple Primary; Rats; Rats, Inbred ACI; Retinyl Esters; Vitamin A | 1988 |
Anti-carcinogenic activity of d-limonene during the initiation and promotion/progression stages of DMBA-induced rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Cyclohexenes; Diet; Female; Limonene; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Terpenes | 1988 |
Suppression of growth of 7,12-dimethylbenzanthracene-induced mammary carcinomas in female rats by repeated whole-body hyperthermia (41-42 degrees C).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Female; Hyperthermia, Induced; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1988 |
Reduction of estrogen and prolactin receptors in 7,12-dimethylbenz(a)anthracene-induced rat mammary tumor by high doses of estrogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Receptors, Prolactin; Tamoxifen | 1987 |
Influence of caffeine and/or coffee consumption on the initiation and promotion phases of 7,12-dimethylbenz(a)anthracene-induced rat mammary gland tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Caffeine; Cocarcinogenesis; Coffee; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1988 |
Influence of caffeine consumption on 7,12-dimethylbenz(a)anthracene-induced mammary gland tumorigenesis in female rats fed a chemically defined diet containing standard and high levels of unsaturated fat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Caffeine; Cocarcinogenesis; Coffee; Dietary Fats; Fats, Unsaturated; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1988 |
Influence of caffeine consumption on carcinomatous and normal mammary gland development in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Caffeine; Cocarcinogenesis; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H | 1988 |
Inheritance of a genetic factor from the Copenhagen rat and the suppression of chemically induced mammary adenocarcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Alleles; Animals; Estrus; Female; Hormones; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Species Specificity | 1988 |
Modulation of chemical carcinogenesis in rats by alkyl lysophospholipids.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Female; Leukemia, Experimental; Lysophospholipids; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Experimental; Organophosphates; Organophosphorus Compounds; Phospholipid Ethers; Rats; Rats, Inbred Strains | 1987 |
Protective effect of dietary brussels sprouts against mammary carcinogenesis in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Brassica; Diet; Female; Glucosinolates; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1988 |
Feasibility of using lower doses of chemopreventive agents in a combination regimen for cancer protection.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diterpenes; Drug Combinations; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Retinyl Esters; Selenium; Vitamin A; Vitamin E | 1988 |
[Epithelial-stromal interrelations in mammary gland tumors induced by 7,12-dimethylbenzanthracene in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Epithelium; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Microscopy, Electron; Rats | 1988 |
Application of a mathematical model for two component receptor binding to two high affinity oestrogen binding sites in nuclei from DMBA rat mammary tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Cell Nucleus; Estradiol; Mammary Neoplasms, Experimental; Mathematics; Models, Theoretical; Rats; Receptors, Estrogen; Tamoxifen | 1988 |
Effects of dietary primrose oil on mammary tumorigenesis induced by 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Corn Oil; Dietary Fats; Fatty Acids, Essential; Female; gamma-Linolenic Acid; Linoleic Acids; Mammary Neoplasms, Experimental; Oenothera biennis; Plant Oils; Rats; Rats, Inbred Strains | 1987 |
[Translocation of protein kinase C from cytosol into cell membranes after treatment with estradiol and enzyme activation in target cells].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biological Transport; Cell Membrane; Cytosol; Enzyme Activation; Estradiol; Female; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Protein Kinase C; Rats; Rats, Inbred Strains | 1988 |
Adrenal regulation of mammary tumorigenesis in female Sprague-Dawley rats: incidence, latency, and yield of mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Age Factors; Animals; Cell Division; Female; Hypophysectomy; Mammary Neoplasms, Experimental; Metyrapone; Necrosis; Ovariectomy; Prolactin; Rats; Time Factors | 1988 |
Adrenal regulation of mammary tumorigenesis in female Sprague-Dawley rats: histopathology of mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Adrenalectomy; Age Factors; Animals; Carcinoma; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylprednisolone; Neoplasm Transplantation; Pituitary Gland; Rats; Time Factors | 1988 |
Inhibition of mammary carcinogenesis in rats by dietary restriction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Diet, Reducing; DNA; Estrogens; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1988 |
Actions of an endogenous antitumorigenic agent on mammary tumor development and modeling analysis of its capacity for interacting with DNA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzeneacetamides; DNA, Neoplasm; Female; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Orchiectomy; Piperidines; Piperidones; Rats; Tamoxifen | 1988 |
Prevention of mammary carcinogenesis in rats by pregnancy: effect of full-term and interrupted pregnancy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abortion, Induced; Animals; DNA; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Time Factors | 1988 |
Active immunization to luteinizing hormone releasing hormone to inhibit the induction of mammary tumors in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estradiol; Estrus; Female; Gonadotropin-Releasing Hormone; Immunization; Mammary Neoplasms, Experimental; Organ Size; Ovary; Progesterone; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Uterus | 1988 |
Changes in the hormone dependency of DMBA-induced rat mammary tumors with reference to the effect of tamoxifen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred Strains; Receptors, Estradiol; Receptors, Progesterone; Tamoxifen | 1988 |
Differential expression of a novel gene, WDNM1, in nonmetastatic rat mammary adenocarcinoma cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Clone Cells; DNA; Gene Expression Regulation; Genes, ras; Mammary Neoplasms, Experimental; Molecular Sequence Data; Rats; Transcription, Genetic | 1988 |
Therapeutic effect of the arotinoid Ro 15-0778 on chemically induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Retinoids; Tamoxifen | 1988 |
Inhibition of 7,12-dimethylbenz(a)anthracene- and N-nitrosomethylurea-induced rat mammary cancer by dietary flavonol quercetin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diet; Female; Flavonoids; Mammary Neoplasms, Experimental; Methylnitrosourea; Quercetin; Rats; Rats, Inbred Strains; Weight Gain | 1988 |
Effects of the aromatase inhibitor 7 alpha-(4'-amino)phenylthio-4-androstene-3,17-dione on 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstadienes; Androstenedione; Animals; Aromatase Inhibitors; Estradiol; Estrogens; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred Strains | 1988 |
Comparison of 7,12-dimethylbenz[a]anthracene metabolism and DNA binding in mammary epithelial cells from three rat strains with differing susceptibilities to mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; DNA Damage; Epithelium; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1988 |
Characterization of the antitumor activity of hexadecylphosphocholine (D 18506).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Choline; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Leukocytosis; Mammary Neoplasms, Experimental; Phosphorylcholine; Rats; Rats, Inbred Strains; Sarcoma, Experimental | 1988 |
[Modeling of differentiation and physiological involution in the tissues of induced cancer of the mammary gland].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Survival; Estrogens; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Papaverine; Rats; Tamoxifen; Vitamin A | 1988 |
Glucocorticoid-induced alterations of morphology and growth of fibrosarcoma cells derived from 7,12-dimethylbenz(a)anthracene rat mammary tumor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cells, Cultured; Corticosterone; Dexamethasone; Dose-Response Relationship, Drug; Fibrosarcoma; Fluorescent Antibody Technique; Glucocorticoids; Hydrocortisone; Mammary Neoplasms, Experimental; Rats | 1988 |
Eicosanoid synthesis in 7,12-dimethylbenz(a)anthracene-induced mammary carcinomas in Sprague-Dawley rats fed primrose oil, menhaden oil or corn oil diet.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Corn Oil; Dietary Fats; Eicosanoic Acids; Fatty Acids; Fatty Acids, Essential; Female; Fish Oils; gamma-Linolenic Acid; Linoleic Acids; Mammary Neoplasms, Experimental; Models, Biological; Oenothera biennis; Plant Oils; Rats; Rats, Inbred Strains | 1988 |
The combined effects of dietary protein and fat intake during the promotion phase of 7,12-dimethylbenz(a)anthracene-induced breast cancer in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Dietary Fats; Dietary Proteins; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Risk Factors; Time Factors | 1988 |
Effects of dietary fat on long-term growth and mammary tumorigenesis in female Sprague-Dawley rats given a low dose of DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Dietary Fats; Disease Models, Animal; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors | 1988 |
Effects of the aromatase inhibitor 4-hydroxyandrostenedione and the antiandrogen flutamide on growth and steroid levels in DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Anilides; Animals; Cell Division; Female; Flutamide; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Steroids | 1988 |
Composition of phospholipid molecular species from mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Calcium, Dietary; Female; Mammary Neoplasms, Experimental; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains | 1988 |
Effects of tamoxifen, estradiol benzoate and medroxyprogesterone acetate on the growth of DMBA-induced rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Estradiol; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Medroxyprogesterone Acetate; Rats; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen | 1985 |
Effects of selenium on 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis and DNA adduct formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; DNA; DNA, Neoplasm; Kinetics; Liver; Male; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenium; Tritium | 1985 |
Plasma estradiol and prolactin levels and their response to stress in two strains of rat with different sensitivities to 7,12-dimethylbenz[a]anthracene-induced tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Corticosterone; Estradiol; Female; Mammary Neoplasms, Experimental; Prolactin; Rats; Rats, Inbred Strains; Restraint, Physical; Stress, Physiological; Time Factors | 1985 |
Attenuation of the anticarcinogenic action of selenium by vitamin E deficiency.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Female; In Vitro Techniques; Lipid Peroxides; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Selenium; Vitamin E; Vitamin E Deficiency | 1985 |
Effects of diazoxide-induced reversible diabetes on chemically induced autochthonous mammary carcinomas in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diazoxide; DNA; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Flow Cytometry; Insulin; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Time Factors | 1985 |
Effects of nonsteroidal antiestrogens, analog II and tamoxifen, on a metastatic transplantable rat mammary tumor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Experimental; Neoplasm Metastasis; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Tamoxifen | 1985 |
Inhibitory action of Piper betle on the initiation of 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Areca; Female; Mammary Neoplasms, Experimental; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred Strains | 1985 |
Modulation of rat mammary carcinogenesis by indomethacin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animal Feed; Animals; Dose-Response Relationship, Drug; Female; Indomethacin; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1985 |
The role of high levels of dietary fat in 7,12-dimethylbenzanthracene-induced mouse mammary tumorigenesis: lack of an effect on lipid peroxidation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Cocarcinogenesis; Dietary Fats; Dose-Response Relationship, Drug; Female; Hormones; Lipid Peroxides; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C | 1985 |
Early local reaction and lymph node permeation of rat carcinoma HH9-cl 14 cells. An immunohistological approach.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antibodies, Monoclonal; Antibody-Dependent Cell Cytotoxicity; Female; Immunoenzyme Techniques; Lymph Nodes; Lymphatic Metastasis; Macrophages; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; T-Lymphocytes; Time Factors | 1985 |
Requirement of essential fatty acid for mammary tumorigenesis in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Dietary Fats; Fatty Acids, Essential; Female; Linoleic Acid; Linoleic Acids; Mammary Neoplasms, Experimental; Prostaglandins; Rats; Rats, Inbred Strains; Regression Analysis | 1985 |
Vascular resistance characteristics of 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors and normal tissues as studied in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; In Vitro Techniques; Mammary Neoplasms, Experimental; Perfusion; Rats; Rats, Inbred Strains; Vascular Resistance | 1985 |
Effects of aromatase inhibitors, aminoglutethimide, and 4-hydroxyandrostenedione on cyclic rats and rats with 7,12-dimethylbenz(a)anthracene-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Estradiol; Estrus; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Oxidoreductases; Pregnancy; Rats; Rats, Inbred Strains | 1985 |
Chemical induction of ovarian tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Adenoma; Animals; Carcinoma, Squamous Cell; Female; Fenitrothion; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovarian Neoplasms; Rats; Uterine Neoplasms | 1985 |
Inhibitory action of aminoglutethimide on DMBA-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Animals; Diet; Female; Mammary Neoplasms, Experimental; Rats | 1985 |
Selenium inhibition of chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adipose Tissue; Animals; Diet; Female; Glutathione Peroxidase; Lipid Peroxides; Liver; Mammary Neoplasms, Experimental; Precancerous Conditions; Rats; Selenium; Vitamin E | 1985 |
Hormone-dependent changes of blood vessels in DMBA-induced rat mammary carcinoma and its regression studied by 3H-thymidine autoradiography.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Autoradiography; Capillaries; Castration; DNA, Neoplasm; Endothelium; Estradiol; Female; Male; Mammary Neoplasms, Experimental; Rats; Testosterone; Thymidine | 1985 |
Carcinogenic responses to chemicals applied directly to rat mammary glands in situ.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogens; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains | 1985 |
The inhibitory effect of 5-acetoxy-2-(4-acetoxyphenyl)-1-ethyl-3-methylindole (D 16726) on estrogen-dependent mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Female; Humans; Indoles; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen | 1985 |
Sequential assays of hormone receptors and the Tritiated Thymidine Labeling Index in 7,12-dimethylbenz(a)anthracene-induced rat mammary cancers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Castration; Doxorubicin; Female; Mammary Neoplasms, Experimental; Mesothelin; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Thymidine; Tritium | 1985 |
The effects of arotinoids on rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Benzoates; Body Weight; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Retinoids | 1985 |
Synthesis and pharmacokinetics of 131I labeled benzoyl derivatives of estrone and estradiol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Estradiol; Estrone; Female; Iodine Radioisotopes; Isotope Labeling; Kinetics; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tissue Distribution | 1985 |
Determination of the number of events required for mammary carcinogenesis in the Sprague-Dawley female rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Models, Biological; Oncogenes; Probability; Rats; Rats, Inbred Strains | 1985 |
Effects of medroxyprogesterone acetate on DMBA-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cytoplasm; Female; Mammary Neoplasms, Experimental; Medroxyprogesterone; Rats; Receptors, Estrogen; Receptors, Progesterone | 1985 |
Maintenance of milk protein gene expression in a subpopulation of 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinoma cells grown on attached collagen gels.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Caseins; Cells, Cultured; Female; Gene Expression Regulation; Half-Life; Hydrocortisone; Insulin; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Milk Proteins; Organ Culture Techniques; Pregnancy; Prolactin; Rats; Rats, Inbred Strains; RNA, Messenger; Transcription, Genetic | 1985 |
Mechanism of growth enhancement of 7,12-dimethylbenz[a]-anthracene-induced mammary tumors in rats given high polyunsaturated fat diet.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adipose Tissue; Animals; Cell Division; Dietary Fats; DNA, Neoplasm; Energy Intake; Estrus; Fatty Acids, Unsaturated; Female; Lipid Metabolism; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1985 |
Mode of action of selenium inhibition of 7,12-dimethylbenz[a]anthracene-induced mouse mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Glutathione Peroxidase; Lipid Peroxides; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Selenium | 1985 |
Effect of human chorionic gonadotrophin on 7,12-dimethylbenz[a]anthracene-induced DNA binding and repair synthesis by rat mammary epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cells, Cultured; Chorionic Gonadotropin; DNA; DNA Repair; Epithelial Cells; Epithelium; Female; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1985 |
Factors influencing differential growth of rat mammary tumor fragments and cells transplanted in gland-free and gland-containing mammary fat pads.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adipose Tissue; Animals; Female; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Rats; Rats, Inbred Lew | 1985 |
Abnormal deposition of basement membrane and connective tissue components in dimethylbenzanthracene-induced rat mammary tumours: an immunocytochemical and ultrastructural study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Basement Membrane; Collagen; Connective Tissue; Female; Fibronectins; Histocytochemistry; Immunoenzyme Techniques; Laminin; Mammary Neoplasms, Experimental; Microscopy, Electron; Rats; Rats, Inbred WF | 1985 |
[Relation between hormone dependency and the estrogen receptor of mammary carcinoma--comparative study of rat and human mammary tumors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Female; Humans; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Receptors, Estrogen | 1985 |
Biological activities of tamoxifen aziridine, an antiestrogen-based affinity label for the estrogen receptor, in vivo and in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Affinity Labels; Animals; Cell Division; Female; Humans; In Vitro Techniques; Mammary Neoplasms, Experimental; Organ Size; Plasminogen Activators; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen; Uterus | 1985 |
Relation between the mass of the pituitary gland and the incidence and mass of mammary tumors in female rats after dimethylbenzanthracene administration.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Female; Mammary Neoplasms, Experimental; Pituitary Gland; Rats; Rats, Inbred Strains | 1985 |
Age-related changes in mammary gland DNA synthesis as a limiting factor for mammary tumorigenesis in rats and its implication for human breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Breast Neoplasms; DNA; Female; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Maternal Age; Pregnancy; Rats; Risk | 1985 |
Inhibitory effects of superior cervical ganglionectomy on dimethylbenz(a)anthracene-induced mammary tumors in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Ganglia, Sympathetic; Light; Mammary Neoplasms, Experimental; Pineal Gland; Rats; Rats, Inbred Strains; Sensory Deprivation; Smell; Sympathectomy | 1985 |
The interaction of dietary fat and antiestrogen treatment on DMBA-induced mammary tumors in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Rats, Inbred Strains; Tamoxifen | 1985 |
Melatonin and malignant disease.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Line; Female; Hormones; Humans; Mammary Neoplasms, Experimental; Melatonin; Neoplasms, Experimental; Rats; Reference Values; Risk | 1985 |
Relationship between histological structure and lactate dehydrogenase isoenzyme pattern of rat mammary tumors induced by dimethylbenz(a)-anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cystadenoma; Female; Isoenzymes; L-Lactate Dehydrogenase; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Myocardium; Rats; Rats, Inbred Strains | 1985 |
Estrogen-binding in vitro by DMBA-induced rat mammary tumors: its relationship to hormone responsiveness.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Binding Sites; Castration; Estradiol; Female; In Vitro Techniques; Mammary Neoplasms, Experimental; Rats | 1974 |
The effect of bovine growth hormone on growth of mammary tumors in hypophysectomized rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Female; Growth Hormone; Hypophysectomy; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1974 |
Link between carcinogenicity and hepatic metabolism of 7,12-dimethylbenz(alpha)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Coumarins; Female; Glucose-6-Phosphatase; Liver; Mammary Neoplasms, Experimental; Mixed Function Oxygenases; Pregnancy; Rats | 1974 |
Uptake of progesterone-14C and estradiol-3H by isolated normal mammary parenchymal and cancer cells of the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cells, Cultured; Estradiol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Microbial Collagenase; Progesterone; Rats | 1974 |
Benzo[d,e]testosterone acetate: a new synthetic steroid with dissociation of biological activities.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Estrogen Antagonists; Female; Gonadotropins; Male; Mammary Neoplasms, Experimental; Mice; Rats; Rats, Inbred Strains; Testosterone; Testosterone Congeners | 1967 |