9,10-dimethyl-1,2-benzanthracene has been researched along with Disease Exacerbation in 95 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (1.05) | 18.7374 |
1990's | 26 (27.37) | 18.2507 |
2000's | 30 (31.58) | 29.6817 |
2010's | 36 (37.89) | 24.3611 |
2020's | 2 (2.11) | 2.80 |
Authors | Studies |
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Gestl, SA; Gunther, EJ; Li, S | 1 |
Belmonte, B; Best, K; Botto, M; Castro Seoane, R; Fossati-Jimack, L; Gulino, A; Jackson, WD; Köhl, J; Strid, J; Tian, K | 1 |
Allen, AM; Alorro, M; Chand, AL; Clyne, CD; Connelly, AA; Coulson, R; Deb, S; Ernst, M; George, AJ; Hannan, NJ; Harrison, CA; Kumar, B; Lazarus, KA; Liew, SH; Morrow, RJ; O'Toole, SA; Parslow, AC; Poh, A; Putoczki, T; Vargas, AC; Walton, KL; Yeap, EFW; Yee, NS | 1 |
Christensen, R; Füchtbauer, AC; Füchtbauer, EM; Gunnarsson, A; Jensen, UB; Owens, DM; Ramsing, M | 1 |
Anguish, LJ; Coonrod, SA; Horibata, S; McElwee, JL; McLean, D; Mohanan, S; Mukai, C; Sams, K; Yan, A | 1 |
Bharath, G; Chaitanyakumar, A; Gomathi, A; Gothandam, KM; Jayasindu, M; Mageswari, A; Pavan Kumar, JGS; Shravan, JS; Srinivasan, R | 1 |
Al-Dhaheri, W; Hassouna, I; Karam, SM | 1 |
Anandakumar, P; Sakthisekaran, D; Vanitha, MK | 1 |
Askeland, RW; Fisher, RA; Maity, B; O'Malley, Y; Stewart, A; Sugg, SL | 1 |
Croxford, R; Deghan Manshadi, S; Ishiguro, L; Kim, YI; Medline, A; Renlund, R; Sohn, KJ | 1 |
Aoto, Y; Goitsuka, R; Hachiya, T; Hirose, S; Isogai, E; Katsuragi, Y; Kominami, R; Nakamura, T; Okumura, K; Saito, M; Sakakibara, Y; Wakabayashi, Y | 1 |
Alves-Júnior, MJ; Anhê, GF; de Moraes Schenka, NG; De Souza, PC; de Souza, VB; Hyslop, S; Jampietro, J; Rennó, AL; Rocha, RM; Schenka, AA; Soares, FA; Vassallo, J | 1 |
Ali, N; Ali, R; Hasan, SK; Khan, AQ; Khan, R; Majed, F; Mehdi, SJ; Nafees, S; Rashid, S; Sultana, S | 1 |
Alves, ÂV; Cardoso, JC; de Albuquerque-Júnior, RL; de Alencar, SM; dos Santos, EP; Gomes, MZ; Massarioli, AP; Padilha, FF; Rabelo, AS; Ribeiro, DR | 1 |
Brylka, H; Kraus, A; Niemann, C; Petersson, M; Reuter, K; Schettina, P | 1 |
Athar, M; Cochran, JB; Elmets, CA; McKay, KM; Nasti, TH; Timares, L; Tsuruta, Y; Yusuf, N | 1 |
Apostoli, AJ; Di Lena, MA; Nicol, CJ; Peterson, NT; Roche, JM; Rubino, RE; Schneider, MM; SenGupta, SK | 1 |
Bao, R; Bechill, J; Bindokas, VP; Faber, PW; Lingen, MW; Spiotto, MT; Zhong, R | 1 |
Adams, DJ; Balmain, A; Chin, D; Delrosario, R; Halliwill, KD; Hewinson, J; Hirst, G; Jen, KY; McCreery, MQ; Vuong, P | 1 |
de Gruijl, FR; Gerritsen, HC; Song, JY; Sterenborg, HJ; Thomas, G; Truong, H; Tuk, B | 1 |
Devlin, KL; Harrison, LM; Hursting, SD; Lashinger, LM; LeBourgeois, P; Mambo, E; Sanford, T | 1 |
Al-Dhaheri, WS; Al-Salam, S; Hassouna, I; Karam, SM | 1 |
Gaafar, AI; Grawish, ME; Nasif, WA; Zaher, AR | 1 |
Arbeit, JM; Kladney, RD; Martin, RJ; Neumann, RG; Scortegagna, M | 1 |
Fischer, SM; Herschman, HR; Huang, SC; Ishikawa, TO; Kumar, IP; Kusewitt, D; Machado, HB; Wong, KP | 1 |
Benakanakere, I; Besch-Williford, C; Carroll, CE; Hyder, SM | 1 |
Box, NF; Boyle, GM; Dai, D; Gonzalez, V; Lozano, G; Murao, K; Pollock, PM; Powell, MB; Robinson, SE; Robinson, WA; Roop, DR; Stiegmann, RA; Terzian, T; Torchia, EC | 1 |
Becks, L; Broadway, M; Burson, H; Christophe, C; Itoh, K; Kleiner-Hancock, HE; Mathis, M; McLarty, J; Orchard, E; Prince, M; Pruitt, K; Shi, R; Yamamoto, M; Zhang, S | 1 |
Akakura, S; Bouchard, R; Bshara, W; Gelman, IH; Morrison, C | 1 |
Abel, E; Fischer, SM; Mikulec, C; Pavone, A; Rundhaug, J; Surh, I | 1 |
Jin, JY; Leshin, B; Lutfeali, S; Miliani de Marval, P; Selim, MA; Zhang, JY | 1 |
Aciole, GT; Canguss, MC; de C Monteiro, JS; de Oliveira, SC; Dos Santos, JN; Pinheiro, AN; Sousa, JA | 1 |
Abel, E; Fischer, SM; Mikulec, C; Pavone, A; Rundhaug, JE; Simper, M; Surh, I | 1 |
Chaiswing, L; Dhar, SK; Oberley, TD; St Clair, DK; Tangpong, J | 1 |
Chen, L; Chen, RM; Han, J; Hong, L; Hu, WY; Liao, R; Sun, P; Xu, Z; Yoshizuka, N; Yu, G | 1 |
Bendt, KM; Edwards, RH; Moore, DT; Nielsen, JN; Raab-Traub, N; Shair, KH | 1 |
Carlson, BA; Green, JE; Hatfield, DL; Hoeneroff, MJ; Hudson, TS; Muller, WJ; Sordillo, L; Young, HA | 1 |
Kreft, M; Sachs, N; Secades, P; Song, JY; Sonnenberg, A; van Hulst, L | 1 |
Braeuning, A; Münzel, PA; Schwarz, M | 1 |
Barton, JK; Brewer, MA; Hoyer, PB; Marion, SL; Rice, PF; Utzinger, U; Watson, JM | 1 |
Hirose, M; Imai, T; Matsui, T; Mitsumori, K; Onodera, H; Takagi, H; Takizawa, T; Ueda, M; Yasuhara, K | 1 |
Campbell, DH; Macdiarmid, J; Stevenson, D; Wilson, JB | 1 |
Athar, M; Bhasin, G; Kauser, H | 1 |
Bohlmann, R; Gieschen, H; Heinrich, N; Hoffmann, J; Hofmeister, H; Kroll, J; Künzer, H; Lichtner, RB; Nishino, Y; Parczyk, K; Sauer, G; Schneider, MR; Ulbrich, HF | 1 |
Aguilar, M; Garcia del Moral, R; Martín-Oliva, D; Muñoz-Gámez, JA; Nuñez, MI; O'Valle, F; Oliver, FJ; Ruiz de Almodóvar, JM; Valenzuela, MT | 1 |
Hirose, M; Imai, T; Matsui, T; Mitsumori, K; Niho, N; Shibutani, M; Ueda, M | 1 |
Glick, A; Hennings, H; Michael, E; Smith, L; Vijayachandra, K; Woodworth, CD; Yuspa, SH | 1 |
Balmain, A; Del Rosario, R; Mao, JH; Perez-Losada, J; To, MD; Wu, D | 1 |
Gurley, KE; Kelly-Spratt, KS; Kemp, CJ; Yasui, Y | 1 |
Sakai, Y; Shirakawa, M; Tanaka, M | 1 |
Gorgoulis, VG; Papaevangeliou, D; Papassava, P; van Dam, H; Vlahopoulos, S; Zoumpourlis, V | 1 |
Amatangelo, MD; Bassi, DE; Cukierman, E; Klein-Szanto, AJ | 1 |
Boscá, L; Cano, A; Millán, O; Peinado, H; Pérez-Sala, D; Rico, D; Rojas, JM; Stamatakis, K; Zarich, N | 1 |
Fabian, CJ; Kimler, BF; Petroff, BK; Ting, AY | 1 |
Feng, L; Wang, Z | 1 |
Boulden, J; Chang, MY; Duhadaway, JB; Muller, AJ; Prendergast, GC; Soler, AP; Sutanto-Ward, E | 1 |
Christov, K; Mehta, R; Wiehle, RD | 1 |
Hasumura, M; Hirose, M; Imai, T; Onose, J; Ueda, M | 1 |
Lambert, PF; Maufort, JP; Pitot, HC; Williams, SM | 1 |
Abel, E; Beltran, L; Carbajal, S; Chan, KS; Clifford, J; Digiovanni, J; Kataoka, K; Peavey, M; Sano, S; Shen, J | 1 |
Arabzadeh, A; Troy, TC; Turksen, K | 1 |
Cline, JM; Lorenzo, PS; Luke, CT; Oki-Idouchi, CE | 1 |
Goddard, M; Johnson, F; Lecuyer, D; McLean, J; Scaiano, JC; Thansandote, A; Tryphonas, L | 1 |
Kertai, P; Pocsai, Z; Varga, C | 1 |
Fürstenberger, G; Kopp-Schneider, A | 1 |
Beltràn, L; DiGiovanni, J; Rho, O; Xian, W | 1 |
Russo, IH; Russo, J | 1 |
Cabrini, RL; Folco, A; Itoiz, ME; Morales, A; Schwint, AE | 1 |
Conti, CJ; Stern, MC | 1 |
Aldaz, CM; Liao, QY; Paladugu, A; Rehm, S; Wang, H | 1 |
Furuya, Y; Onizawa, K; Saginoya, H; Yoshida, H | 1 |
Hirose, M; Mizoguchi, Y; Shirai, T; Tanaka, H; Yamaguchi, T; Yaono, M | 1 |
Agarwal, R; Katiyar, SK; Mohan, RR; Mukhtar, H | 1 |
Ferro, VA; Stimson, WH | 1 |
Dhingra, JK; Feld, MS; Itzkan, I; Kabani, S; Manoharan, R; McMillan, K; Shapshay, SM; Zhang, X | 1 |
Pena, JC; Rudin, CM; Thompson, CB | 1 |
Beltran, L; Conti, CJ; DiGiovanni, J; DuBowski, A; Johnston, DA; Rupp, T | 1 |
Demarchi, M; Depiante-Depaoli, M; Hliba, E; Remedi, MM | 1 |
Brinkley, BR; Greenhalgh, DA; He, D; Jiang, A; Roop, DR; Wang, XJ; Zhong, L | 1 |
Binder, RL; Bolontrade, MF; Conti, CJ; Gimenez-Conti, IB; Stern, MC; Zenklusen, JC | 1 |
Archer, MC; Korkola, JE | 1 |
Iida, K; Kato, M; Kurita, K; Tatematsu, M; Yamamoto, M; Yoshida, K | 1 |
Deng, C; Fernandez-Salas, E; Hennings, H; Mirosh, E; Morgan, DL; Shalizi, A; Stanulis, E; Weinberg, WC; Yuspa, SH | 1 |
Bodner, S; Kamijo, T; Randle, DH; Sherr, CJ; van de Kamp, E | 1 |
Fischer, SM; La, E; Locniskar, MF; Muga, SJ | 1 |
Bamezai, R; Singh, A; Singh, SP | 1 |
Alfano, RR; Guo, Y; Ho, PP; Liu, F; Savage, HE; Schantz, SP | 1 |
Russo, IH; Russo, J; Srivastava, P | 1 |
Lambert, PF; Liem, A; Miller, JA; Song, S | 1 |
Benavides, F; Conti, CJ; Klingelberger, EA; Stern, MC | 1 |
Dreckschmidt, NE; Jansen, AP; Oberley, TD; Verma, AK; Verwiebe, EG; Wheeler, DL | 1 |
Klein-Szanto, AJ; Nettesheim, P; Olson, AC; Topping, DC | 1 |
Blouin, MJ; Kopchick, JJ; Pollak, M; Zhang, JC | 1 |
Jang, TJ; Kim, DK | 1 |
Clark, K; Collard, JG; Malliri, A; Michiels, F; van der Kammen, RA; van der Valk, M | 1 |
4 review(s) available for 9,10-dimethyl-1,2-benzanthracene and Disease Exacerbation
Article | Year |
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Non-melanoma skin cancer in mouse and man.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Disease Progression; Genes, p53; Genes, ras; Humans; Melanoma; Mice; Mutation; Neoplasm Invasiveness; Neoplastic Stem Cells; Papilloma; Risk Assessment; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 2013 |
Role of the epidermal growth factor receptor and transforming growth factor alpha in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Disease Progression; ErbB Receptors; Mice; Models, Biological; Papilloma; Phorbol Esters; Precancerous Conditions; Skin Neoplasms; Transforming Growth Factor alpha | 1994 |
Experimentally induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diet; Disease Models, Animal; Disease Progression; Disease Susceptibility; Female; Gonadal Steroid Hormones; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Radiation-Induced; Rats; Rats, Inbred F344; Rats, Sprague-Dawley | 1996 |
Genetic susceptibility to tumor progression in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Crosses, Genetic; Disease Progression; Disease Susceptibility; Hyperplasia; Mice; Mice, Inbred SENCAR; Mice, Inbred Strains; Papilloma; Precancerous Conditions; Skin; Skin Neoplasms | 1996 |
91 other study(ies) available for 9,10-dimethyl-1,2-benzanthracene and Disease Exacerbation
Article | Year |
---|---|
A Multistage Murine Breast Cancer Model Reveals Long-Lived Premalignant Clones Refractory to Parity-Induced Protection.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Clone Cells; Disease Progression; Epithelial Cells; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Mutation; Parity; Pregnancy; Proto-Oncogene Proteins p21(ras); Time Factors; Wnt Signaling Pathway; Wnt1 Protein | 2020 |
C3 Drives Inflammatory Skin Carcinogenesis Independently of C5.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Complement Activation; Complement C3; Complement C5; Complement Membrane Attack Complex; Disease Models, Animal; Disease Progression; Humans; Mice; Mice, Knockout; Mice, Transgenic; Neoplasms, Experimental; Receptor, Anaphylatoxin C5a; Receptors, Complement; Signal Transduction; Skin; Skin Neoplasms; Tumor Escape | 2021 |
The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiotensin II Type 1 Receptor Blockers; Animals; Biopsy; Breast Neoplasms; Carcinogenesis; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Cell Proliferation; Disease Progression; Female; Humans; Immunohistochemistry; Interleukin-6; Losartan; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Neoplasm Invasiveness; Phosphorylation; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; STAT3 Transcription Factor; Tumor Burden; Tumor Necrosis Factor-alpha; Up-Regulation | 2017 |
Constitutive transgene expression of Stem Cell Antigen-1 in the hair follicle alters the sensitivity to tumor formation and progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Ly; Carcinogenesis; Clone Cells; Colony-Forming Units Assay; Disease Progression; Female; Hair Follicle; Integrases; Membrane Proteins; Mice, Inbred C57BL; Mice, Transgenic; Morphogenesis; Skin; Tetradecanoylphorbol Acetate; Transgenes | 2017 |
PAD2 overexpression in transgenic mice augments malignancy and tumor-associated inflammation in chemically initiated skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Male; Mice; Mice, Transgenic; Papilloma; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2017 |
Oral administration of lyophilized Dunaliella salina, a carotenoid-rich marine alga, reduces tumor progression in mammary cancer induced rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Anticarcinogenic Agents; Apoptosis; Benz(a)Anthracenes; Breast Neoplasms; Carotenoids; Caspase 3; Cell Proliferation; Chlorophyta; Disease Progression; Female; Humans; Lipid Peroxidation; Plant Extracts; Rats; Rats, Sprague-Dawley; Rats, Wistar | 2017 |
Genetic polymorphisms and protein expression of P53 and BRCA1 in preneoplastic and neoplastic rat mammary glands.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; BRCA1 Protein; Cell Cycle; Cell Nucleus; Cytoplasm; Disease Progression; Exons; Female; Gene Expression Regulation, Neoplastic; Genetic Variation; Mammary Neoplasms, Experimental; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Precancerous Conditions; Protein Transport; Rats; Tumor Suppressor Protein p53 | 2018 |
Taurine abrogates mammary carcinogenesis through induction of apoptosis in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; bcl-2-Associated X Protein; Carcinogens; Caspases; Disease Progression; Female; Mammary Neoplasms, Experimental; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley; Taurine; Tumor Suppressor Protein p53 | 2018 |
Regulator of G protein signaling 6 is a novel suppressor of breast tumor initiation and progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms; Carcinogenesis; Cell Line, Tumor; Disease Progression; DNA Damage; Epithelial Cells; ErbB Receptors; Female; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Receptors, Estrogen; RGS Proteins; Signal Transduction; Tumor Suppressor Protein p53 | 2013 |
Folic acid supplementation promotes mammary tumor progression in a rat model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; bcl-2-Associated X Protein; Dietary Supplements; Disease Progression; Female; Folic Acid; Gene Expression; Humans; Mammary Neoplasms, Experimental; Neoplasm Proteins; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Tumor Burden | 2014 |
Meis1 regulates epidermal stem cells and is required for skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult Stem Cells; Animals; Carcinogens; Carcinoma; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Gene Expression Regulation, Neoplastic; Hair Follicle; Homeodomain Proteins; Keratinocytes; Mice; Mice, Transgenic; Multipotent Stem Cells; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Decreased expression of stem cell markers by simvastatin in 7,12-dimethylbenz(a)anthracene (DMBA)-induced breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Biomarkers; Biomarkers, Tumor; Carcinogens; Disease Progression; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Mammary Neoplasms, Experimental; Necrosis; Neoplastic Stem Cells; Rats; Rats, Sprague-Dawley; Simvastatin | 2015 |
Tannic acid mitigates the DMBA/croton oil-induced skin cancer progression in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Croton; Cyclooxygenase 2; Disease Progression; Drug Evaluation, Preclinical; Female; Glutathione; Hydrogen Peroxide; Interleukin-6; Lipid Peroxidation; Mice; Nitric Oxide Synthase Type II; Plant Oils; Proliferating Cell Nuclear Antigen; Skin; Skin Neoplasms; Tannins; Xanthine Oxidase | 2015 |
Inhibition of DMBA-induced Oral Squamous Cells Carcinoma Growth by Brazilian Red Propolis in Rodent Model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Brazil; Carcinoma, Squamous Cell; Chemoprevention; Chromatography, High Pressure Liquid; Disease Progression; Dose-Response Relationship, Drug; Male; Mice; Mouth Neoplasms; Propolis; Rats | 2015 |
Interfering with stem cell-specific gatekeeper functions controls tumour initiation and malignant progression of skin tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Apoptosis; Carcinogenesis; Carcinogens; Cell Lineage; Cell Proliferation; Cell Separation; Cell Transformation, Neoplastic; Crosses, Genetic; Disease Progression; DNA Damage; Epidermis; Flow Cytometry; Humans; Lymphoid Enhancer-Binding Factor 1; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Phenotype; Sebaceous Gland Neoplasms; Skin Neoplasms; Stem Cells; Tumor Suppressor Protein p53; Ultraviolet Rays | 2015 |
A murine model for the development of melanocytic nevi and their progression to melanoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line, Tumor; Cell Separation; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Disease Progression; Melanoma; Mice; Mice, Nude; Mutation; Neoplasm Proteins; Nevus, Pigmented; ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
Opposing roles for mammary epithelial-specific PPARγ signaling and activation during breast tumour progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; BRCA1 Protein; Cytokines; Disease Progression; Epithelial Cells; Female; Gene Deletion; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice, Knockout; Models, Biological; Organ Specificity; PPAR gamma; Signal Transduction; Tumor Burden | 2015 |
Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Carcinoma, Verrucous; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; Disease Progression; DNA Transposable Elements; Female; Humans; Mice; Mice, Transgenic; Mouth Neoplasms; Mutagenesis, Insertional; Neoplasm Invasiveness; Oncogenes; Papilloma; Papillomaviridae; Receptor, Notch1; Skin Neoplasms; Specific Pathogen-Free Organisms; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Virus Infections; Uterine Cervical Neoplasms | 2015 |
Evolution of metastasis revealed by mutational landscapes of chemically induced skin cancers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Clonal Evolution; Crosses, Genetic; Disease Progression; DNA Copy Number Variations; Epithelial-Mesenchymal Transition; Female; Humans; Male; Mice; Mutation; Phylogeny; ras Proteins; Skin Neoplasms | 2015 |
Studying skin tumourigenesis and progression in immunocompetent hairless SKH1-hr mice using chronic 7,12-dimethylbenz(a)anthracene topical applications to develop a useful experimental skin cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Carcinogenesis; Carcinogens; Disease Models, Animal; Disease Progression; Female; Mice; Mice, Hairless; Skin Neoplasms | 2017 |
Stage-Specific MicroRNAs and Their Role in the Anticancer Effects of Calorie Restriction in a Rat Model of ER-Positive Luminal Breast Cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Caloric Restriction; Disease Progression; Disease-Free Survival; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; MCF-7 Cells; MicroRNAs; Oligoribonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Tumor Burden | 2016 |
Characterization of breast cancer progression in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Progression; Female; Immunohistochemistry; Mammary Neoplasms, Experimental; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar | 2008 |
Long-term effect of Spirulina platensis extract on DMBA-induced hamster buccal pouch carcinogenesis (immunohistochemical study).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cheek; Cricetinae; Dietary Supplements; Disease Progression; Humans; Immunohistochemistry; Male; Mesocricetus; Mouth Neoplasms; Proliferating Cell Nuclear Antigen; Spirulina; Time | 2010 |
Hypoxia-inducible factor-1alpha suppresses squamous carcinogenic progression and epithelial-mesenchymal transition.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle Proteins; Disease Progression; Epithelial Cells; Hypoxia-Inducible Factor 1, alpha Subunit; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Selenium-Binding Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 2009 |
Positron emission tomography imaging of DMBA/TPA mouse skin multi-step tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Progression; Female; Fluorodeoxyglucose F18; Glucose; Mice; Papilloma; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tomography, X-Ray Computed | 2010 |
Synthetic progestins differentially promote or prevent 7,12-dimethylbenz(a)anthracene-induced mammary tumors in sprague-dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cytoprotection; Disease Progression; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Female; Mammary Neoplasms, Experimental; Neoplasm Staging; Placebos; Progesterone Congeners; Rats; Rats, Sprague-Dawley | 2010 |
p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cellular Senescence; Clone Cells; Disease Models, Animal; Disease Progression; Humans; Imidazoles; Melanocytes; Melanoma; Mice; Mice, Inbred C57BL; Nevus; Pigmentation; Piperazines; Proto-Oncogene Proteins; Skin Neoplasms; Staining and Labeling; Survival Analysis; Transcription, Genetic; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases | 2010 |
Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animal Feed; Animals; Coumarins; Cytosol; Disease Progression; Drug Design; Female; Genotype; Liver; Lymphoma; Mammary Neoplasms, Animal; Mice; Mice, Inbred ICR; Mice, Knockout; NF-E2-Related Factor 2 | 2010 |
Carcinogen-induced squamous papillomas and oncogenic progression in the absence of the SSeCKS/AKAP12 metastasis suppressor correlate with FAK upregulation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; A Kinase Anchor Proteins; Animals; Cell Cycle Proteins; Disease Progression; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2011 |
Upregulation of the EP1 receptor for prostaglandin E2 promotes skin tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Blotting, Western; Carcinogens; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Disease Progression; Epidermis; Female; Humans; Mice; Mice, Hairless; Mice, Transgenic; Receptors, Prostaglandin E, EP1 Subtype; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays; Up-Regulation | 2011 |
CYLD inhibits tumorigenesis and metastasis by blocking JNK/AP1 signaling at multiple levels.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cysteine Endopeptidases; Deubiquitinating Enzyme CYLD; Disease Progression; Epidermal Cells; Epidermis; Humans; Hyperplasia; Immunoblotting; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases; Lymphatic Metastasis; Mice; Mice, Transgenic; Mutation; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitination | 2011 |
Influence of laser phototherapy (λ660 nm) on the outcome of oral chemical carcinogenesis on the hamster cheek pouch model: histological study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cheek; Cricetinae; Disease Progression; Head and Neck Neoplasms; Low-Level Light Therapy; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Squamous Cell Carcinoma of Head and Neck | 2011 |
The EP1 receptor for prostaglandin E2 promotes the development and progression of malignant murine skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Disease Progression; Female; Immunohistochemistry; Mice; Mice, Transgenic; Receptors, Prostaglandin E, EP1 Subtype; Skin Neoplasms | 2012 |
Manganese superoxide dismutase is a p53-regulated gene that switches cancers between early and advanced stages.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Disease Progression; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genes, Reporter; Genes, Synthetic; Humans; Mice; Mice, Transgenic; Neoplasm Proteins; Papilloma; Promoter Regions, Genetic; Recombinant Fusion Proteins; Skin Neoplasms; Sp1 Transcription Factor; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Suppressor Protein p53 | 2011 |
A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cell Movement; Cell Transformation, Neoplastic; Cytoskeleton; Disease Progression; Endothelial Cells; Focal Adhesion Protein-Tyrosine Kinases; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Neovascularization, Pathologic; Papilloma; Phorbols; Protein Serine-Threonine Kinases; Skin Neoplasms; Vascular Endothelial Growth Factor Receptor-2 | 2012 |
Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) and LMP2A function cooperatively to promote carcinoma development in a mouse carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cell Transformation, Viral; Disease Models, Animal; Disease Progression; Gene Expression; Genes, ras; Keratin-14; Mice; Mice, Inbred BALB C; Mice, Transgenic; Mutation; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Viral Matrix Proteins | 2012 |
Selenoproteins reduce susceptibility to DMBA-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Progression; Female; Genotype; Mammary Neoplasms, Animal; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C57BL; Mice, Knockout; RNA, Transfer, Amino Acid-Specific; Selenocysteine; Selenoproteins | 2012 |
Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Adhesion; Cell Cycle; Cell Differentiation; Cell Lineage; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Epidermis; Hair Follicle; Integrin alpha3; Keratin-15; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Skin Neoplasms; Staining and Labeling | 2012 |
Two-photon excited fluorescence imaging of endogenous contrast in a mouse model of ovarian cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Aging; Animals; Biomarkers, Tumor; Collagen; Cyclohexenes; Disease Progression; Elastin; Female; Image Interpretation, Computer-Assisted; Linear Models; Lipofuscin; Mice; Microscopy, Fluorescence, Multiphoton; NAD; Ovarian Neoplasms; Ovary; Vinyl Compounds | 2013 |
Enhancing effects of beta-estradiol 3-benzoate but not methoxychlor on the promotion/progression stage of chemically-induced mammary carcinogenesis in ovariectomized rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Disease Progression; Estradiol; Female; Mammary Neoplasms, Animal; Methoxychlor; Ovary; Rats; Rats, Sprague-Dawley; Time Factors | 2002 |
The latent membrane protein 1 of Epstein-Barr virus and loss of the INK4a locus: paradoxes resolve to cooperation in carcinogenesis in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; Disease Progression; Disease Susceptibility; DNA; DNA Primers; Epidermal Cells; Epidermis; Epithelial Cells; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Mice; Mice, Knockout; Mice, Transgenic; Nasopharyngeal Neoplasms; Papilloma; Polymerase Chain Reaction; Skin Neoplasms; Viral Matrix Proteins | 2003 |
Free radical generating agents lead to the rapid progression of benign skin tumors to carcinoma in iron-overloaded mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzene Derivatives; Benzoyl Peroxide; Carcinogens; Carcinoma, Squamous Cell; Disease Progression; Female; Free Radicals; Hydrogen Peroxide; Iron; Iron Overload; Iron-Dextran Complex; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Characterization of new estrogen receptor destabilizing compounds: effects on estrogen-sensitive and tamoxifen-resistant breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease Models, Animal; Disease Progression; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Modulators; Estrogens; Female; Humans; Injections, Subcutaneous; Methylnitrosourea; Mice; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Transplantation, Heterologous | 2004 |
Crosstalk between PARP-1 and NF-kappaB modulates the promotion of skin neoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Binding Sites; Carcinogens; Cell Division; Disease Progression; Enzyme Activation; Epidermis; Epithelium; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence; Mitosis; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2004 |
Lack of significant effects of genistein on the progression of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in ovariectomized Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Disease Progression; Dose-Response Relationship, Drug; Estrogens; Female; Genistein; Incidence; Mammary Neoplasms, Experimental; Ovariectomy; Random Allocation; Rats; Rats, Sprague-Dawley | 2003 |
Strain-dependent differences in malignant conversion of mouse skin tumors is an inherent property of the epidermal keratinocyte.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Disease Progression; Epidermis; Genetic Predisposition to Disease; Humans; Infant, Newborn; Keratinocytes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred SENCAR; Mice, Nude; Oncogene Proteins, Viral; Papilloma; Papillomaviridae; Papillomavirus E7 Proteins; Repressor Proteins; Skin Neoplasms; Species Specificity | 2004 |
Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Progression; Genes, ras; Heterozygote; Homozygote; Loss of Heterozygosity; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Mutation; Papilloma; Protein Tyrosine Phosphatases; PTEN Phosphohydrolase; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins | 2004 |
p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Carcinogens; Carcinoma, Squamous Cell; Crosses, Genetic; Cyclin-Dependent Kinase Inhibitor p16; Disease Progression; Genes, ras; Genotype; Loss of Heterozygosity; Lymphatic Metastasis; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Papilloma; Polymerase Chain Reaction; Protein Binding; Proto-Oncogene Proteins p21(ras); Signal Transduction; Tumor Suppressor Protein p14ARF; Tumor Suppressor Protein p53; Up-Regulation | 2004 |
Lymphocyte changes in peripheral blood, spleen, and liver in DMBA-induced squamous cell carcinoma of mouse cheek skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; B-Lymphocytes; Body Weight; Carcinogens; Carcinoma, Squamous Cell; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cheek; Disease Progression; Flow Cytometry; Killer Cells, Natural; Liver; Lymphocyte Subsets; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mouth Neoplasms; Organ Size; Spleen; T-Lymphocytes; Time Factors | 2004 |
Overexpression of activating transcription factor-2 is required for tumor growth and progression in mouse skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Activating Transcription Factor 2; Activating Transcription Factor 3; Animals; Carcinogens; Carcinoma; Cell Cycle; Cell Growth Processes; Cyclic AMP Response Element-Binding Protein; Cyclin A; Cyclin D1; Disease Progression; Genes, jun; Mice; Mice, Inbred BALB C; Mice, SCID; Phosphorylation; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Transcription Factor AP-1; Transcription Factors; Transfection; Up-Regulation | 2004 |
Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Communication; Cell Differentiation; Disease Progression; Extracellular Matrix; Fibroblasts; Mice; Models, Biological; Skin Neoplasms; Stromal Cells | 2005 |
Potentiation of tumor formation by topical administration of 15-deoxy-delta12,14-prostaglandin J2 in a model of skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Cyclooxygenase 2; Disease Progression; Drug Interactions; Female; Immunologic Factors; Keratinocytes; Mice; Papilloma; Prostaglandin D2; Skin Neoplasms | 2006 |
Characterization of a preclinical model of simultaneous breast and ovarian cancer progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Alkylating Agents; Animals; Carcinogens; Carcinoma, Intraductal, Noninfiltrating; Cell Proliferation; Cells, Cultured; Cocarcinogenesis; Cyclooxygenase 2; Disease Models, Animal; Disease Progression; Epithelium; Estrogen Receptor alpha; Estrogens; Female; Hyperplasia; Immunoenzyme Techniques; Ki-67 Antigen; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovarian Neoplasms; Precancerous Conditions; Rats; Rats, Inbred F344 | 2007 |
Chemopreventive effect of celecoxib in oral precancers and cancers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Carcinogens; Celecoxib; Chemoprevention; Cricetinae; Cyclooxygenase 2 Inhibitors; Disease Progression; Dose-Response Relationship, Drug; Male; Mesocricetus; Mouth Neoplasms; Precancerous Conditions; Pyrazoles; Random Allocation; Sulfonamides; Time Factors; Treatment Outcome | 2006 |
Bin1 ablation in mammary gland delays tissue remodeling and drives cancer progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptor Proteins, Signal Transducing; Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Disease Progression; Female; Gene Deletion; Genes, ras; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Molecular Sequence Data; Nerve Tissue Proteins; Pregnancy; Tumor Suppressor Proteins | 2007 |
Anti-progestins suppress the growth of established tumors induced by 7,12-dimethylbenz(a)anthracene: comparison between RU486 and a new 21-substituted-19-nor-progestin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Proliferation; Disease Progression; Female; Hormone Antagonists; Mammary Neoplasms, Experimental; Mifepristone; Norpregnadienes; Progesterone Congeners; Progestins; Rats; Rats, Sprague-Dawley | 2007 |
Lack of a significant effect of arctiin on development of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in ovariectomized Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Disease Progression; Dose-Response Relationship, Drug; Female; Furans; Glucosides; Incidence; Mammary Neoplasms, Experimental; Ovariectomy; Random Allocation; Rats; Rats, Sprague-Dawley | 2007 |
Human papillomavirus 16 E5 oncogene contributes to two stages of skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Codon; Disease Progression; DNA; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Oncogene Proteins, Viral; Paraffin; Phenotype; ras Proteins; Skin Neoplasms | 2007 |
Forced expression of a constitutively active form of Stat3 in mouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Epidermis; Keratinocytes; Mice; Mice, Transgenic; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate | 2008 |
Changes in the distribution pattern of Claudin tight junction proteins during the progression of mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Claudin-1; Disease Progression; Epidermis; Gene Expression; Membrane Proteins; Mice; Models, Animal; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tight Junctions; Time Factors | 2007 |
RasGRP1 overexpression in the epidermis of transgenic mice contributes to tumor progression during multistage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Progression; Epidermis; Female; Guanine Nucleotide Exchange Factors; Keratinocytes; Male; Mice; Mice, Transgenic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
A 60-Hz magnetic field increases the incidence of squamous cell carcinomas in mice previously exposed to chemical carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Disease Progression; Free Radicals; Magnetics; Mice; Mice, Inbred SENCAR; Papilloma; Skin; Skin Neoplasms | 1995 |
Urinary and serum mutagenicity studies with rats bearing experimental tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Composition; Chromatography, Ion Exchange; Dimethylnitrosamine; Disease Progression; Frameshift Mutation; Ion Exchange Resins; Kidney Neoplasms; Leukemia, Myelomonocytic, Acute; Liver Neoplasms, Experimental; Mutagenicity Tests; Nephroma, Mesoblastic; Polymers; Polystyrenes; Polyvinyls; Rats; Rats, Inbred F344; Salmonella typhimurium; Urine | 1995 |
Malignant progression of papillomas induced by the initiation--promotion protocol in NMRI mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Disease Models, Animal; Disease Progression; Female; Mice; Mice, Inbred Strains; Models, Statistical; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
AgNOR mark epithelial foci in malignant transformation in hamster cheek pouch carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cell Nucleus; Cell Transformation, Neoplastic; Cheek; Coloring Agents; Cricetinae; Disease Progression; Epithelium; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Nucleolus Organizer Region; Silver | 1996 |
Allelotypic and cytogenetic characterization of chemically induced mouse mammary tumors: high frequency of chromosome 4 loss of heterozygosity at advanced stages of progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Carcinogens; Chromosomes; Disease Progression; Female; Gene Deletion; Heterozygote; Karyotyping; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasm Staging; Neoplasm Transplantation | 1996 |
Fluorescence photography as a diagnostic method for oral cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Adenoid Cystic; Carcinoma, Squamous Cell; Cricetinae; Diagnosis, Differential; Disease Progression; Female; Fluorescence; Humans; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Muscles; Neoplasm Invasiveness; Papilloma; Photography; Predictive Value of Tests; Protoporphyrins; Reproducibility of Results; Sensitivity and Specificity; Stomatitis; Tongue Neoplasms | 1996 |
Effects of green tea catechins on the progression or late promotion stage of mammary gland carcinogenesis in female Sprague-Dawley rats pretreated with 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Carcinogens; Catechin; Disease Progression; Female; Mammary Neoplasms, Experimental; Neoplasm Staging; Rats; Rats, Sprague-Dawley; Tea | 1997 |
Protection against induction of mouse skin papillomas with low and high risk of conversion to malignancy by green tea polyphenols.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Carcinoma, Squamous Cell; Catechin; Cocarcinogenesis; Disease Progression; Diterpenes; Flavonoids; Mice; Mice, Inbred SENCAR; Papilloma; Phenols; Plant Extracts; Polymers; Skin Neoplasms; Tea; Terpenes | 1997 |
Immunoneutralisation of gonadotrophin releasing hormone: a potential treatment for oestrogen-dependent breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Atrophy; Disease Progression; Estradiol; Female; Genitalia, Female; Gonadotropin-Releasing Hormone; Immunization; Immunoglobulin G; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Palpation; Rats; Rats, Sprague-Dawley | 1997 |
Diagnosis of head and neck precancerous lesions in an animal model using fluorescence spectroscopy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma in Situ; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Color; Cricetinae; Disease Models, Animal; Disease Progression; Fluorescence; Follow-Up Studies; Hyperplasia; Lasers; Leukoplakia, Oral; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Neoplasm Invasiveness; Precancerous Conditions; Spectrometry, Fluorescence; Stomatitis | 1998 |
A Bcl-xL transgene promotes malignant conversion of chemically initiated skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; bcl-X Protein; Carcinogens; Cell Transformation, Neoplastic; Disease Progression; Mice; Mice, Transgenic; Papilloma; Proto-Oncogene Proteins c-bcl-2; Skin Neoplasms; Transgenes | 1998 |
Papillomas at high risk for malignant progression arising both early and late during two-stage carcinogenesis in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Progression; Female; Mice; Papilloma; Risk Factors; Skin Neoplasms | 1998 |
Relationship between immune state and tumor growth rate in rats bearing progressive and non-progressive mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinoma, Ductal, Breast; Disease Progression; Erythrocytes; Female; Hemagglutination Tests; Hypersensitivity, Delayed; Immunity, Cellular; Immunization; Macrophage Activation; Macrophages, Peritoneal; Mammary Neoplasms, Experimental; Nitric Oxide; Rats; Rats, Wistar; Reactive Oxygen Species; Sheep | 1998 |
Analysis of centrosome abnormalities and angiogenesis in epidermal-targeted p53172H mutant and p53-knockout mice after chemical carcinogenesis: evidence for a gain of function.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Centrosome; Disease Progression; Endothelial Growth Factors; Genes, p53; Humans; Lymphokines; Mice; Mice, Knockout; Neovascularization, Pathologic; Papilloma; Phenotype; Point Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thrombospondin 1; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Angiogenesis is an early event in the development of chemically induced skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; Disease Progression; Mice; Mice, Inbred SENCAR; Neovascularization, Pathologic; Papilloma; Skin Neoplasms | 1998 |
Resistance to mammary tumorigenesis in Copenhagen rats is associated with the loss of preneoplastic lesions.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Progression; Drug Resistance; Female; Genes, ras; Genes, Tumor Suppressor; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Rats; Rats, Inbred WF | 1999 |
Strong expression of glutathione S-transferase placental form in early preneoplastic lesions and decrease with progression in hamster buccal pouch carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cheek; Cricetinae; Disease Progression; Glutathione Transferase; Hyperplasia; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Papilloma; Precancerous Conditions | 1999 |
Genetic deletion of p21WAF1 enhances papilloma formation but not malignant conversion in experimental mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Differentiation; Biomarkers; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Disease Progression; Epidermis; Gene Deletion; Genes, p53; Genotype; Hyperplasia; Mice; Mice, Knockout; Mitotic Index; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 1999 |
Tumor spectrum in ARF-deficient mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cell Lineage; Cocarcinogenesis; Disease Progression; Female; Fibrosarcoma; Gene Deletion; Genes, p53; Genotype; Loss of Heterozygosity; Lymphoma; Male; Mice; Mice, Knockout; Neoplasms, Experimental; Neoplasms, Nerve Tissue; Neoplasms, Radiation-Induced; Neoplastic Stem Cells; Nuclear Proteins; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Time Factors; Tumor Suppressor Protein p14ARF; Tumor Suppressor Protein p53 | 1999 |
Altered expression of interleukin-1 receptor antagonist in different stages of mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Blotting, Northern; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Polarity; Cytoplasm; Disease Progression; Epidermis; Gene Expression Regulation, Neoplastic; Hyperplasia; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Keratinocytes; Mice; Mice, Inbred SENCAR; Neoplasm Proteins; Papilloma; Precancerous Conditions; RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1999 |
Modulatory potential of clocimum oil on mouse skin papillomagenesis and the xenobiotic detoxication system.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chemoprevention; Disease Progression; Inactivation, Metabolic; Male; Mice; Ocimum; Ocimum basilicum; Papilloma; Plant Oils; Skin Neoplasms; Xenobiotics | 1999 |
Subsurface tumor progression investigated by noninvasive optical second harmonic tomography.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cheek; Cricetinae; Disease Progression; Neoplasms, Experimental; Time Factors; Tomography | 1999 |
Inhibition of rat mammary tumorigenesis by human chorionic gonadotropin associated with increased expression of inhibin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chorionic Gonadotropin; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Genes, myc; Humans; Immunohistochemistry; Inhibins; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Proto-Oncogene Proteins c-myc; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcriptional Activation | 1999 |
Human papillomavirus types 16 E6 and E7 contribute differently to carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Mutation; Oncogene Proteins, Viral; Papilloma; Papillomavirus E7 Proteins; Repressor Proteins; Severity of Illness Index; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Allelotype analysis of chemically induced squamous cell carcinomas in F(1) hybrids of two inbred mouse strains with different susceptibility to tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Carcinogens; Carcinoma, Squamous Cell; Chimera; Crosses, Genetic; Disease Progression; Genetic Predisposition to Disease; Genotype; Humans; Loss of Heterozygosity; Mice; Mice, Inbred SENCAR; Microsatellite Repeats; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Protein kinase C-epsilon transgenic mice: a unique model for metastatic squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; Disease Progression; Female; Hair Follicle; Isoenzymes; Lymphatic Metastasis; Male; Mice; Mice, Transgenic; Protein Kinase C; Protein Kinase C-epsilon; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Quantitative analysis of disturbed cell maturation in dysplastic lesions of the respiratory tract epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma in Situ; Carcinoma, Squamous Cell; Cell Differentiation; Disease Progression; Epithelial Cells; Female; Lung Neoplasms; Metaplasia; Precancerous Conditions; Rats; Rats, Inbred F344; Trachea; Transplantation, Heterotopic | 1980 |
Reduced mammary gland carcinogenesis in transgenic mice expressing a growth hormone antagonist.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Birth Weight; Carcinogens; Disease Progression; Female; Growth Hormone; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Risk Factors | 2001 |
Inducible nitric oxide synthase expression of tumor and stromal cells is associated with the progression of 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Progression; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Neoplasm Invasiveness; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Reference Values; Stromal Cells | 2002 |
Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Division; Disease Progression; Gene Dosage; Genotype; Guanine Nucleotide Exchange Factors; Immunohistochemistry; Keratins; Mice; Mice, Knockout; Proteins; ras Proteins; Skin Neoplasms; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Tetradecanoylphorbol Acetate | 2002 |