9,10-dimethyl-1,2-benzanthracene has been researched along with Cell Transformation, Neoplastic in 518 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 196 (37.84) | 18.7374 |
1990's | 88 (16.99) | 18.2507 |
2000's | 102 (19.69) | 29.6817 |
2010's | 128 (24.71) | 24.3611 |
2020's | 4 (0.77) | 2.80 |
Authors | Studies |
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Bessonneau, V; Chen, Z; Dang, NM; Gurdogan, H; Hillegass, M; Joshi, S; Kanefsky, J; Rahulkannan, V; Rudel, R; Russo, J; Santucci-Pereira, J; Schneider, SS; Ser-Dolansky, J; Su, Y | 1 |
Bhattacharjee, K; Choudhury, Y; Laskar, YB; Mazumder, PB; Nath, M; Talukdar, AD | 1 |
Jothi, EA; Lv, P; Xiao, Z; Yang, J; Zhang, H | 1 |
Kreft, M; Krotenberg Garcia, A; Ramovs, V; Sonnenberg, A | 1 |
Chang, A; Huang, KM; Huang, Y; Liu, MM; Mei, N; Orlando, R; Parsa, C; Yeung, S; Zhang, S | 1 |
Callejas-Valera, JL; Cimas, FJ; Fernandez-Aroca, DM; Garcia-Gil, E; García-Olmo, DC; Gutkind, JS; Hernández-Losa, J; Marcos, P; Melgar-Rojas, P; Ortega-Muelas, M; Pascual-Serra, R; Ramón Y Cajal, S; Roche, O; Ruiz-Hidalgo, MJ; Sanchez-Prieto, R | 1 |
Bhatia, D; Bishayee, A; Mandal, A | 2 |
Ananthakrishnan, D; Gunasekaran, K; Pugalendhi, P; Rajakumar, T; Thilagavathi, S | 1 |
Alexander-Savino, C; Chen, L; Gillespie, K; Gilmore, ES; Hayden, MS; Oleksyn, D; Poligone, B; Zhao, J | 1 |
Balmain, A; Del Rosario, R; Harris, S; Kandyba, E; Reeves, MQ | 1 |
Balaiya, V; Johnson, LK; Koster, MI; Lakshmanachetty, S | 1 |
Cao, X; Feng, X; Howard, EW; Jiang, Y; Kim, YM; Kosanke, SD; Li, S; Ma, Z; Parris, AB; Yang, S; Yang, X | 1 |
Hall, JR; House, JS; Jima, DD; Messenger, ZJ; Smart, RC; Tam, HW; Tokarz, DA | 1 |
Asfaha, S; Boland, K; Gordon, D; Jin, G; Johnson, K; Lad, S; Londono, D; Morris, RJ; Park, H; Patterson, KS; Readio, N; Singh, A; Trempus, C; Wang, TC; Yang, X | 1 |
Ganapathy, S; Gopalakrishnan, T; Namasivayam, N; Veeran, V | 1 |
Gubareva, EA; Maidin, MA; Panchenko, AV; Tyndyk, ML; Vinogradova, LA | 1 |
Awasthi, S; Horne, D; Salgia, R; Singhal, J; Singhal, SS; Vonderfecht, S | 1 |
Aleksandrov, VA; Bespalov, VG | 1 |
Karthikeyan, S; Manimaran, A; Manoharan, S; Prabhakar, MM; Rajasekaran, D; Vasudevan, K; Wani, SA | 1 |
Cescon, D; Chio, II; Dominguez-Brauer, C; Elia, AJ; Ghazarian, D; Gorrini, C; Haight, J; Hao, Z; Harris, IS; Inoue, S; Itsumi, M; Li, WY; Mak, TW; McCracken, S; Melino, G; Penn, LJ; Sasaki, M; Silvester, J; Snow, B; Ueda, T; Wakeham, A; Yamamoto, K; You-Ten, A; Zhou, L | 1 |
Arora, N; Bansal, MP; Koul, A | 1 |
Hamid, RA; Khaza'ai, H; Yazan, LS; Yeong, LT | 1 |
Hong, JI; Jung, BG; Kim, TH; Ko, JH; Lee, BJ; Lee, JA; Park, YS | 1 |
Kathiresan, S; Mariadoss, AV; Muthusamy, R | 1 |
Altenburg, J; Camarillo, I; Harvey, KA; Jones-Hall, Y; Mariash, C; Siddiqui, RA; Terry, C; Walker, C; Xu, Z | 1 |
Fujiwara, K; Ghosh, S; Liang, P; Morien, E; Nagase, H; Soma, M | 1 |
Bouker, KB; de Assis, S; Hilakivi-Clarke, LA; Jin, L; Wang, M | 1 |
Cogliati, B; Dagli, ML; de Oliveira, KD; Tedardi, MV | 1 |
Accurso, BT; Casto, BC; Galioto, RL; Knobloch, TJ; Warner, BM; Yu, Z | 1 |
Manimaran, A; Manoharan, S; Rajasekaran, D; Singh, AK; Suresh, K; Vasudevan, K | 1 |
Ali, H; Dixit, S | 1 |
Hogg, N; McNeill, E | 1 |
Chawsheen, HA; Colburn, NH; Gerard, M; Jiang, H; Mishra, M; Toledano, MB; Wei, Q; Wu, L; Young, MR | 1 |
Albrecht, PP; Amin, S; Bility, MT; Borland, MG; Gonzalez, FJ; Krishnan, P; Lee, C; Lin, JM; Marcus, CB; Perdew, GH; Peters, JM; Shan, W | 1 |
Cipolat, S; Hoste, E; Natsuga, K; Quist, SR; Watt, FM | 1 |
Blanco, MA; Bronson, RT; Chakrabarti, R; Chekmareva, M; Guo, F; Haffty, BG; Hua, Y; Kang, Y; Lu, X; Shen, M; Smith, HA; Wan, L; Wei, Y; Wu, H; Xing, Y; Yuan, M; Yuan, S | 1 |
Aoto, Y; Goitsuka, R; Hachiya, T; Hirose, S; Isogai, E; Katsuragi, Y; Kominami, R; Nakamura, T; Okumura, K; Saito, M; Sakakibara, Y; Wakabayashi, Y | 1 |
Fujimoto, H; Fukuda, I; Lee, KM; Nishino, T; Okubo, C; Tsuji, H; Yoshimura, H | 1 |
Jeena, K; Kuttan, R; Liju, VB | 1 |
Bobrov, N; Bojková, B; Bomba, A; Demečková, V; Kassayová, M; Kisková, T; Kubatka, P; Mikeš, J; Orendáš, P; Péč, M; Strojný, L | 1 |
Bürgler, CD; Filler, RB; Fraser, JA; Girardi, M; Golubets, K; Kucher, CL; Lewis, JM; Liao, H; Tigelaar, RE; Zhao, PY | 1 |
Brylka, H; Kraus, A; Niemann, C; Petersson, M; Reuter, K; Schettina, P | 1 |
Carr, TD; Feehan, RP; Hall, MN; Rüegg, MA; Shantz, LM | 1 |
Benetti, R; Blasco, MA; Buemi, V; Dinami, R; Jordi, F; Petti, E; Schoeftner, S | 1 |
Aruna, PR; Ebenezar, J; Ganesan, S | 1 |
Gu, X; Jin, R; Li, G; Li, T; Li, W; Ren, A; Shi, R; Zhang, C; Zhao, Y | 1 |
Chen, Z; Dong, L; Dong, Y; Fang, F; Fu, M; Guo, X; Li, J; Liu, C; Liu, X; Ma, G; Ma, X; Shao, S; Xiao, J; Xue, L; Yang, X; Yu, L; Zhan, Q; Zhang, L; Zhang, W; Zhang, Y; Zhao, Q | 1 |
Bhattacharjee, T; Ingle, A; Krishna, CM; Kumar, P; Maru, G | 1 |
Bao, R; Bechill, J; Bindokas, VP; Faber, PW; Lingen, MW; Spiotto, MT; Zhong, R | 1 |
Bechberger, JF; Laird, DW; Naus, CC; Stewart, MK; Welch, I | 1 |
Abdul Hamid, R; Khaza'ai, H; Mohtarrudin, N; Saiful Yazan, L; Yeong, LT | 1 |
Bishayee, A; Mandal, A | 1 |
Alam, S; Bostanci, Z; Brown, A; Enomoto, LM; Kelleher, SL; Mack, RP; Neumann, C; Soybel, DI | 1 |
Guo, SC; He, YU; Li, QQ | 1 |
Babu, TD; Divya, MK; Lincy, L; Meera, N; Raghavamenon, AC; Salini, S; Seema, M | 1 |
Abba, MC; Aldaz, CM; Gaddis, S; Kil, H; Lee, J; Lu, Y; Shen, J; Simper, MS; Takata, Y; Zhong, Y | 1 |
Berx, G; Declercq, W; Denecker, G; Devos, M; Gilbert, B; Haigh, J; Hochepied, T; Lambert, J; Lemeire, K; Leurs, K; Libbrecht, L; Lippens, S; Mc Guire, C; Van Den Broecke, C; Vandenabeele, P; Vuylsteke, M | 1 |
Asai, M; Asai, N; Enomoto, A; Kato, T; Mii, S; Murakumo, Y; Nagino, M; Shiraki, Y; Sunagawa, M; Takahashi, M | 1 |
Conti, CJ; De Siervi, A; Macias, E; Miliani de Marval, PL; Rodriguez-Puebla, ML; Senderowicz, AM | 1 |
Han, L; Hang, H; He, W; Hopkins, KM; Hu, Z; Lieberman, HB; Liu, Y; Yang, L; Yang, X; Zhang, C; Zhao, Y | 1 |
Barra, JL; Brunotto, M; Malberti, A; Zarate, AM | 1 |
Hori, Y; Iigo, M; Imai, T; Kitahashi, T; Sugimura, T; Takahashi, M; Takasuka, N; Wakabayashi, K; Yoshimi, N | 1 |
Cataisson, C; Hennings, H; Jay, S; Ohman, R; Patel, G; Pearson, A; Tsien, M; Wright, L; Yuspa, SH | 1 |
Ge, JP; Yang, Y; Zhou, ZT | 3 |
Chung, YL; Lee, MY; Pui, NN | 1 |
Barragan, DI; Charron, J; Dumesic, PA; Harada, K; Khavari, PA; Scholl, FA | 1 |
Cheepala, SB; Clifford, JL; Cvek, U; Gill, JN; Kleiner, HE; Loganantharaj, R; Lynch, M; McMillian, A; Syed, Z; Trutschl, M; Yin, W | 1 |
Cao, YT; Gong, RG; Li, A; Wang, CM; Wang, XY; Wen, YM; Yang, S; Yi, XZ; Yu, T | 1 |
Arlt, VM; Fürstenberger, G; Phillips, DH; Schmeiser, HH; Takamura-Enya, T | 1 |
Boily, G; He, XH; Jardine, K; McBurney, MW; Pearce, B | 1 |
Dziadziuszko, H; Glosnicka, R; Graczyk, A; Jankowski, D; Jaskiewicz, K; Juzeniene, A; Kaliszewski, M; Kunikowska, D; Kwasny, M; Kwitniewski, M; Ma, LW; Moan, J; Peksa, R | 1 |
Cotsarelis, G; Digiovanni, J; Kataoka, K; Kiguchi, K; Kim, DJ; Rao, D | 1 |
Brinkley, WR; Caulin, C; Chen, Y; Fitzpatrick, J; Katayama, H; Roop, DR; Sen, S; Sheng, H; Torchia, EC | 1 |
Berta, GN; Carlotti, ME; Cavalli, R; Di Carlo, F; Di Scipio, F; Marinos, LM; Salamone, P; Sapino, S; Sprio, AE | 1 |
Beck, GR; Bobe, G; Camalier, CE; Colburn, NH; Perella, CM; Young, MR | 1 |
Azuine, MA; Kapadia, GJ; Shigeta, Y; Suzuki, N; Tokuda, H | 1 |
Banerjee, S; Das, S; Mukherjee, S; Pal, D; Panda, CK; Roy, A | 1 |
Boldrin, NF; de Camargo, JL; de Oliveira, ML; Ferrucio, B; Franchi, CA | 1 |
Finegan, KG; Tournier, C | 1 |
Branstetter, D; Dougall, WC; Erwert, R; Gonzalez-Suarez, E; Jacob, AP; Jones, J; Miller, R; Pinkas, J; Roudier-Meyer, MP | 1 |
Coste, I; Druillennec, S; Eychene, A; Hainaut, P; Hmitou, I; Kfoury, A; Le Corf, K; Lebecque, S; Renno, T | 1 |
Lambert, PF; Liem, A; Mahoney, C; Pitot, HC; Schweizer, J; Stelzer, MK | 1 |
Fukami, K; Hara, E; Hirao, A; Ishikawa, Y; Motoi, N; Ohtani, N; Sone, S; Tajima, T; Takahashi, A; Takeuchi, S; Yamakoshi, K; Yanagi, S; Yoshimoto, S | 1 |
Goyal, PK; Parmar, J; Sharma, P; Verma, P | 1 |
Kennedy, GD; Lambert, PF; Lee, D; Liem, A; Pitot, HC; Stelzer, MK | 1 |
Agrawal, A; Goyal, PK; Verma, P | 1 |
Chen, L; Qin, Z; Wang, C; Xiao, M; Zhang, J | 1 |
Arthur, JS; Chang, S; Iversen, L; Johansen, C; Kragballe, K | 1 |
Bode, AM; Carper, AL; Dong, Z; Kim, MO; Langfald, AK; Li, S; Liu, K; Ma, WY; Reddy, K; Zhang, J; Zhu, F; Zykova, T | 1 |
Costa, I; de Villa, MC; Escrich, E; Escrich, R; Moral, R; Solanas, M; Vela, E | 1 |
Hu, K; Liu, H; Sun, H; Tang, Y; Wu, M; Xiong, J; Yang, Y; Yuan, L | 1 |
de Lumen, BO; Hernández-Ledesma, B; Hsieh, CC | 1 |
Arai, T; Hamashima, Y; Hasegawa, J; Kajimoto, T; Node, M; Suzuki, N; Tanaka, R; Tokuda, H; Tsujii, H; Yamada, T | 1 |
Barker, JR; Becker Buscaglia, LE; Choudhury, SN; Kanakamedala, K; Kumar, M; Li, Y; Liu, MF; Ma, X | 1 |
Brotman, JJ; Judd, NP; Lewis, JS; Pittman, ME; Schreiber, RD; Uppaluri, R; Winkler, AE | 1 |
Albuquerque, RL; Cardoso, JC; Cavalcante, DR; Góis, SM; Oliveira, PS; Padilha, FF; Soares, AF | 1 |
Gong, Z; He, S; Hogendoorn, PC; Krens, SG; Snaar-Jagalska, BE; Spaink, HP; Zhan, H | 1 |
Bikle, DD; Elalieh, H; Elias, PM; Teichert, AE; Welsh, J | 1 |
Bhui, K; Chaturvedi, PK; George, J; Roy, P; Shukla, Y; Singh, M; Srivastava, AK | 1 |
Kim, SH; Li, Q; Lu, H; Lu, HJ; Lu, Q; Sambandam, SA; Thomson, A; Xin, Y | 1 |
Arbeit, JM; Chung, CH; Day, R; Dong, Y; Grabowska, D; Humphrey, P; Kladney, RD; Lewis, J; Li, A; Michel, LS; Wang, J; Weber, JD; Zhang, K | 1 |
Lambert, PF; Liem, A; Pitot, HC; Thomas, MK | 1 |
Chen, JJ; Geng, CZ; Ju, YC; Wu, JH; Yang, HC; Zhao, JA | 1 |
Chen, L; Chen, RM; Han, J; Hong, L; Hu, WY; Liao, R; Sun, P; Xu, Z; Yoshizuka, N; Yu, G | 1 |
Kale, RK; Mendez, E; Rao, AR; Singh, M | 1 |
Beermann, F; Contassot, E; French, LE; Gehrke, S; Jankovic, D; Kerl, K; Preynat-Seauve, O; Schuler, P | 1 |
Anitha, P; Kavitha, K; Nagini, S; Priyadarsini, RV; Thiyagarajan, P | 1 |
Bobrowska, B; Skrajnowska, D; Tokarz, A | 1 |
Kim, Y; Miliani de Marval, PL; Rodriguez-Puebla, ML; Sistrunk, C; Wang, X | 1 |
Binda, E; Cai, L; Filler, RB; Fu, P; Galan, A; Girardi, M; Hayday, A; Kaplan, DH; Kwong, BY; Lewis, J; Modi, BG; Neustadter, J; Overton, JD; Reddy, S; Roberts, SJ; Shlomchik, M; Tigelaar, R | 1 |
DaSilva, SC; Konger, RL; Kozman, AA; Martel, KC; Rezania, S; Sahu, RP; Travers, JB; Warren, SJ; Yao, Y | 1 |
Dahlhoff, M; de Angelis, MH; Rose, C; Schneider, MR; Wolf, E | 1 |
Chen, XX; Guan, XB; Sun, Z; Wu, HR; Zhang, XY | 1 |
Akihisa, T; Fukatsu, M; Kikuchi, T; Kimura, Y; Motoi, T; Seki, A; Suzuki, N; Tokuda, H | 1 |
Akihisa, T; Huang, Y; Inafuku, K; Kikuchi, T; Miura, M; Motohashi, S; Suzuki, N; Suzuki, T; Tokuda, H; Zhang, J | 1 |
Desai, R; Gao, YR; Handelsman, DJ; Jimenez, M; Simanainen, U; Walters, KA; Watson, G | 1 |
Cotsarelis, G; Gordon, D; Li, S; Liu, Y; Morris, RJ; Park, H; Trempus, CS | 1 |
Khan, I; Kondaiah, P; Kumar, N; Nagini, S; Thiyagarajan, P; Vidya Priyadarsini, R | 1 |
Ai, W; Huang, S; Li, J; Liu, C; Wang, TC; Yu, F; Yu, T; Zheng, H | 1 |
Eilers, M; Elsässer, HP; Hönnemann, J; Sanz-Moreno, A; Wolf, E | 1 |
Cross, SS; Elks, PM; Elworthy, S; Judson, EC; McKee, S; Renshaw, SA; Santhakumar, K; van Eeden, FJ; van Rooijen, E; Walmsley, SS | 1 |
Adegboyega, P; Batra, V; Clifford, JL; Coburn, MA; DiGiovanni, J; Gill, JN; Kleiner-Hancock, HE; Mathis, JM; Shi, R; Syed, Z | 1 |
Manoharan, S; Nirmal, MR; Sindhu, G; Vetrichelvi, V; Vinothkumar, V | 1 |
Cho, BC; Choi, JM; Devkota, S; Ha, NY; Kim, H; Lee, HW; Lee, J; Song, J; Sung, YH | 1 |
Granter, SR; Hemler, ME; Knoblich, K; Li, Q; Rabinovitz, I; Sharma, C; Wang, HX; Xu, F; Yang, XH | 1 |
Chida, K; Hakuno, F; Hara, T; Matsumura, S; Takahashi, S | 1 |
Christodoulou, I; Gorgoulis, V; Logotheti, S; Michalopoulos, I; Papaevangeliou, D; Pyrillou, K; Sideridou, M; Tsimaratou, K; Vlahopoulos, S; Zoumpourlis, V | 1 |
Behboudi, A; Karlsson, S; Nilsson, S; Partheen, K; Samuelson, E; Szpirer, C | 1 |
Beltran, L; Carbajal, S; DiGiovanni, J; Hursting, SD; Moore, T | 1 |
Cataisson, C; Dai, RM; Hakim, S; Lyakh, L; Moffitt, BA; Salcedo, R; Schenten, D; Stephens, R; Trinchieri, G; Wright, L; Yi, M; Yuspa, HS | 1 |
Clarke, M; Das, S; Huels, D; Jamieson, T; Jung, A; Neumann, J; Nibbs, RJ; Olson, MF; Samuel, MS; Sansom, OJ; Steele, CW | 1 |
Fezah, O; Hamizah, S; Roslida, AH; Tan, CI; Tan, KL; Tor, YS | 1 |
Balmain, A; Banta, KL; Rosario, RD; To, MD; Westcott, PM | 1 |
Chang, WJ; Chou, HY; Li, TK; Shen, TL; Tai, PH; Yang, YC | 1 |
Bonsignore, L; Drexler, SK; Gross, O; Hermeking, H; Jackstadt, R; Masin, M; Schneider, P; Tardivel, A; Tschopp, J; Yazdi, AS | 1 |
Belloli, S; Beltrami, E; Fassina, A; Fazio, F; Giorgio, M; Marcu, R; Moresco, R; Pelicci, P; Valtorta, S | 1 |
Bradish, JR; DaSilva-Arnold, SC; Kim, YL; Konger, RL; Mehta, SR; Mohamed, DR; Rashid, BM; Sahu, RP; Warren, SJ; Xu, Z | 1 |
Chen, HD; He, CD; Liu, CH; Lu, T; Ma, GZ; Qiao, J; Wei, B; Wei, HC | 1 |
Harrison, AM; Jeganathan, KB; Malureanu, L; Ricke, RM; van Deursen, JM | 1 |
Kreft, M; Sachs, N; Secades, P; Song, JY; Sonnenberg, A; van Hulst, L | 1 |
Baskaran, N; Karthikeyan, S; Manoharan, S; Prabhakar, MM; Silvan, S; Vasudevan, K | 1 |
Baskaran, N; Karthikeyan, S; Manoharan, S; Prabhakar, MM | 1 |
Baskaran, N; Manoharan, S; Singh, AK; Subhasini, R; Suresh, K; Vasudevan, K | 1 |
Baskaran, N; Manoharan, S; Palanimuthu, D; Silvan, S | 1 |
Cheng, KH; Chiou, YS; Ho, CT; Pan, MH; Sang, S; Wang, YJ | 1 |
Anthony, JJ; Hamid, RA; Othman, F; Ting, YL | 1 |
Fukamachi, K; Han, BS; Maeda, M; Ohnishi, T; Takasuka, N; Tsuda, H; Yamasaki, T | 1 |
Duan, K; Li, B; Zheng, G | 1 |
Chen, Y; Rittling, SR | 1 |
Kupper, TS; Morales, RE; Murphy, JE; Scott, J | 1 |
Campbell, DH; Macdiarmid, J; Stevenson, D; Wilson, JB | 1 |
De Jonage-Canonico, MB; Kerdelhué, B; Lenoir, V; Martin, A; Scholler, R | 1 |
Gardner, C; Owens, DM; Romero, MR; Watt, FM | 1 |
Cabieses, F; Fong, HH; Graham, JG; Hawthorne, ME; Jang, DS; Kang, YH; Kinghorn, AD; Mehta, RG; Park, EJ; Pezzuto, JM; Su, BN; Vigo, JS | 1 |
MALTONI, C; PRODI, G | 1 |
ARGUS, MF; KANE, JF; RAY, FE; SAKUNTALA, M | 1 |
Niwa, Y; Sumi, H; Terashima, T | 1 |
Beg, ZH; Iqbal, J; Minhajuddin, M | 1 |
Bowman, L; Castranova, V; Ding, M; Huang, C; Leonard, S; Lu, Y; Shi, X; Vallyathan, V; Wang, L | 1 |
Cado, D; Itoh, T; Kamide, R; Linn, S | 1 |
Fukamachi, K; Hamaguchi, T; Kawaguchi, H; Kusunoki, M; Matsuoka, Y; Ohki, M; Sakakura, T; Shimizu, K; Takasuka, N; Tsuda, H; Ueda, S; Yoshida, H | 1 |
Hirose, M; Imai, T; Matsui, T; Mitsumori, K; Niho, N; Shibutani, M; Ueda, M | 1 |
Barnes, J; Boudreau, N; Cayer, M; Hall, C; Heckman, CA; Kozma, R; Li, Y; Lim, L; Plummer, HK; Urban, JM | 1 |
Glick, A; Hennings, H; Michael, E; Smith, L; Vijayachandra, K; Woodworth, CD; Yuspa, SH | 1 |
Kohno, H; Sugie, S; Suzuki, R; Tanaka, T | 1 |
Jones, J; Kirma, N; Liu, YG; Luthra, R; Mandava, U; Nair, HB; Tekmal, RR | 1 |
Chimeno Zoth, SA; Collet, AM; Heber, E; Itoiz, ME; Schwint, AE | 1 |
Jahnen-Dechent, W; King, LE; Leite-Browning, ML; Matrisian, LM; McCawley, LJ; Ochieng, J | 1 |
Criado, LM; Efeyan, A; Flores, JM; Klatt, P; Martín-Caballero, J; Matheu, A; Pantoja, C; Serrano, M | 1 |
Bai, Y; Edamatsu, H; Kataoka, T; Maeda, S; Saito, H; Satoh, T; Suzuki, N | 1 |
Cabrini, R; Itoiz, ME; Raimondi, A | 1 |
Chen, X; Fang, M; Li, N; Sood, S; Sun, Z; Wang, P; Wang, S; Yang, CS | 1 |
Fischer, SM; He, G; Lubet, RA; Muga, S; Thuillier, P | 1 |
Adamson, ED; English, C; Krones-Herzig, A; Liang, H; Mercola, D; Mittal, S; Soni, T; Urcis, R; Yule, K | 1 |
de Jonage-Canonico, MB; Kerdelhué, B; Lenoir, V; Martin, A; Perrin, MH; Scholler, R | 1 |
Beguinot, F; Formisano, P; Libertini, S; Miele, C; Oriente, F; Perruolo, G; Portella, G; Raciti, GA; Santopietro, S; Troncone, G | 1 |
Aoki, I; Colledge, WH; Foidart, JM; Hata, R; Kato, Y; Koshika, S; Kubota, Y; Nagashima, Y; Sakai, N; Thompson, EW; Tsukuda, M; Yao, M | 1 |
Bugge, TH; Burke, B; Gutkind, JS; List, K; Molinolo, A; Murdock, T; Nielsen, BS; Redeye, V; Sriuranpong, V; Szabo, R | 1 |
Boscá, L; Cano, A; Millán, O; Peinado, H; Pérez-Sala, D; Rico, D; Rojas, JM; Stamatakis, K; Zarich, N | 1 |
Chen, YK; Huse, SS; Lin, LM | 1 |
Chen, WY; Holle, E; Jacquemart, IC; Langenheim, JF; Tomblyn, S | 1 |
Fischer, SM; He, G; Sung, YM | 1 |
Anvari, B; Diagaradjane, P; Wong, MS; Yaseen, MA; Yu, J | 1 |
Cho, YM; Hasumura, M; Hirose, M; Imai, T | 1 |
Ballestín, C; Lara, MF; Paramio, JM; Ruiz, S; Santos, M; Segrelles, C | 1 |
Sánchez-Velar, N; Sherr, DH; Shin, SR; Sonenshein, GE | 1 |
Chen, Z; Hicks, J; Honeycutt, KA; Koster, MI; Miers, M; Nuchtern, J; Roop, DR; Shohet, JM | 1 |
Davies, R; Edwards, RE; Gant, TW; Greaves, P; Ridd, K; Smith, AG; Wolfreys, A; Zhang, SD | 1 |
Bakthavatchalu, V; Chaiswing, L; Oberley, TD; St Clair, DK; Zhao, Y | 1 |
Denning, MF; Gerber, L; Gilliam, AC; Guo, H; Miao, H; Singh, J; Wang, B | 1 |
Beard, P; Chambon, P; Dubey, C; Dubois, N; Essers, MA; Hummler, E; Metzger, D; Offner, S; Oskarsson, T; Roger, C; Trumpp, A | 1 |
Barra, JL; Brunotto, M; Calderón, O; Crosa, M; Malberti, A; Piñas, E; Plavnik, L; Zárate, AM | 1 |
Aromando, RF; Heber, EM; Itoiz, ME; Kreimann, EL; Nigg, DW; Schwint, AE; Trivillin, VA | 1 |
Choi, HG; Kim, JA; Kim, SJ; Lee, ES; Lee, YS; Paek, SH; Park, BC; Yong, CS | 1 |
Boulden, J; Chang, MY; Duhadaway, JB; Muller, AJ; Prendergast, GC; Soler, AP; Sutanto-Ward, E | 1 |
Castranova, V; Kisin, ER; Kommineni, C; Murray, AR; Shvedova, AA; Vallyathan, V | 1 |
Endoh, M; Hamada, S; Hirota, M; Kanno, A; Kimura, K; Masamune, A; Satoh, K; Shimosegawa, T | 1 |
Antal, MC; Castaneda, E; Chambon, P; Desvergne, B; Gariglio, P; Indra, AK; Jiang, M; Kato, S; Loehr, CV; Meng, X; Messaddeq, N; Metzger, D; Wahli, W | 1 |
Jeong, KS; Jeong, WI; Kim, HA; Kim, YK; Lee, JA; Park, DH | 1 |
Niemann, C; Owens, DM; Schettina, P; Watt, FM | 1 |
DeGregorio, MW; Marchisano-Karpman, C; Wurz, GT | 1 |
Bae, DS; Darwiche, N; Glick, AB; Hennings, H; Perez-Lorenzo, R; Ryscavage, A; Wright, L; Yuspa, SH | 1 |
Hasumura, M; Hirose, M; Imai, T; Onose, J; Ueda, M | 1 |
Fischer, SM; Kim, E; Pavone, A; Rundhaug, JE | 1 |
Cheung, HW; Ling, MT; To-Ho, KW; Wang, X; Wong, YC | 1 |
Horie, S; Katsuki, M; Muto, S | 1 |
Andrée, B; Bylaite, M; Kellermann, S; Kloepper, JE; Paus, R; Reifenberger, J; Rüther, U; Ruzicka, T; Walz, M | 1 |
Abel, E; Beltran, L; Carbajal, S; Chan, KS; Clifford, J; Digiovanni, J; Kataoka, K; Peavey, M; Sano, S; Shen, J | 1 |
Dai, C; Lindquist, S; Rogers, AB; Whitesell, L | 1 |
Auttachoat, W; Chi, RP; Guo, TL; Hernandez, DM; Zheng, JF | 1 |
Chen, X; Li, N; Newman, RA; Sood, S; Sun, Z; Yang, CS; Yang, P | 1 |
Chiappetta, G; Costinean, S; Croce, CM; De Martino, I; Fedele, M; Fusco, A; Iuliano, R; Kusewitt, DF; Oberyszyn, TM; Palmieri, D; Server, IN; Visone, R | 1 |
Bardeesy, N; Berger, JH; Bosenberg, MW; Gurumurthy, S; Hezel, AF; Sahin, E | 1 |
Krishnan, R; Maru, G; Patel, R; Ramchandani, A | 1 |
Bansal, MP; Kaur, J; Sharma, M; Sharma, PD | 1 |
Carbajal, S; Clifford, JL; DiGiovanni, J; Kataoka, K; Kim, DJ | 1 |
Hosaka, M; Hyun, KH; Mori, M; Murase, N; Takai, Y | 1 |
Fujita, J; Sugawara, K; Tokuda, H; Yoshida, O | 1 |
Medina, D; Shepherd, FS | 1 |
Deffie, AM; LéJohn, HB | 1 |
Klein-Szanto, AJ; Shiba, M | 1 |
Tachikawa, T; Yamamura, T; Yoshiki, S | 1 |
Bertram, JS; Libby, PR; Merriman, RL | 1 |
Chen, LB; Summerhayes, IC | 1 |
Edelman, AS; Galton, JE; Palladino, MA; Thorbecke, GJ; Xue, B | 1 |
Bar-Eyal, A; Efrati, M; Ehrlich, R; Malatzky, E; Shochat, L; Witz, IP | 1 |
Hozumi, M | 1 |
Digernes, V; Holbrook, KA; Kilkenny, AE; Kulesz-Martin, M; Yuspa, SH | 1 |
Banerjee, MR; Chatterjee, M | 1 |
Cowell, JK | 1 |
Kuszynski, C; Langenbach, R; Nesnow, S; Somogyi, A | 1 |
Levine, AJ; Maltzman, W; Oren, M | 1 |
Arthur, LA; Medina, D; Smith, GH | 1 |
Cooper, GM; Lane, MA; Sainten, A | 1 |
Chen, A; Essex, M; Koh, KS; Rhim, JS | 1 |
Hodges, GM; Nathrath, WJ; Summerhayes, IC; Trejdosiewicz, LK; Wilson, PD | 1 |
Fisher, PB; Howard, DK; Schlom, J | 1 |
Gershon, H; Lichtig, C; Nahas, F | 1 |
Russo, IH; Russo, J; Tait, L | 1 |
Agrawal, HP; Randerath, E; Randerath, K; Reddy, MV | 1 |
DiPaolo, JA; Evans, CH; Greiner, JW | 1 |
Ciocca, DR; Russo, IH; Russo, J; Tay, LK | 1 |
Dederer, E; Goerttler, K; Hesse, B; Loehrke, H; Rosenkranz, G; Schweizer, J | 1 |
Delgado Fdez, R; Main, JH; Mock, D | 1 |
Ito, N; Lurie, AG; Nakatsuka, T; Rippey, RM; Tatematsu, M | 1 |
Bandyopadhyay, SK; Ray, PK | 1 |
Blair, DG; Cooper, CS; Eader, LA; Oskarsson, MK; Tainsky, MA; Vande Woude, GF | 1 |
Juneja, HS; Mhatre, MC; Shah, PN | 1 |
Beebe, DR; Müller, E; Wotiz, HH | 1 |
Banerjee, MR; Chatterjee, M; Som, S | 1 |
Kitamura, Y; Taguchi, T; Yokoyama, M | 1 |
Fürstenberger, G; Goerttler, K; Kinzel, V; Loehrke, H; Marks, F | 1 |
Feren, K; Reith, A; Rigaut, JP; Thiebaut, F | 2 |
Khaetskaia, VI; Khaetskiĭ, IK | 1 |
Russo, J | 1 |
Barrett, JC; Gray, TE; Mass, MJ; Nettesheim, P; Steele, VE | 1 |
Fürstenberger, G; Marks, F | 1 |
Chen, LB; Summerhayes, I | 1 |
Mardanova, GV | 1 |
Dickens, MS; Sorof, S | 1 |
Puntervold, R; Reith, A; Saxholm, HJ | 1 |
Allen, TD; Connell, JR; Harrison, CJ; Ockey, CH | 1 |
Klein-Szanto, AJ; Marchok, AC; Nettesheim, P; Steele, VE; Terzaghi, M; Topping, DC | 1 |
Enaka, K; Ono, T; Umeda, M | 1 |
Banerjee, MR; Iyer, AP | 1 |
Andreeva, EA; Belisheva, NK; Margulis, BA | 1 |
Hill, SD; Rivera, EM; Taylor, M | 1 |
Bromberg, MJ; Toto, M; Toto, PD | 1 |
Cazer, FD; Inbasekaran, MN; Milo, GE; Tejwani, R; Witiak, DT | 1 |
Gohari, K; White, FH | 2 |
Feren, K; Reith, A | 1 |
Christensen, T; Feren, K; Moan, J; Steen, HB | 1 |
Banerjee, MR; Ganguly, N; Ganguly, R; Mehta, NM | 1 |
Moriya, T | 1 |
Johnston, WW; Marchok, AC; Nettesheim, P | 1 |
Chi, JG; Lee, SK; Mori, M; Park, SC; Sakamoto, F; Shrestha, P | 1 |
Chang, RL; Conney, AH; Fisher, C; Huang, MT; Lu, YP; Ma, W; Manchand, PS; Newmark, HL | 1 |
Owens, DM; Smart, RC; Spalding, JW; Tennant, RW | 1 |
Bertrand, O; Fitzgerald, DJ; Mironov, N; Nakazawa, H; Sasaki, K; Yamasaki, H | 1 |
Bauluz, C; Cano, A; Caulín, C; Gandarillas, A; Quintanilla, M | 1 |
Crean, DH; Kamer, AR; Lee, MT; Liebow, C; Mang, TS; Schally, AV | 1 |
Ip, C; Scimeca, JA; Thompson, HJ | 1 |
Qin, JX; Wang, HJ; Zhang, KH | 1 |
Chiang, T; Chou, LS; Chou, MY; Hsieh, SC; Li, SY; Lin, MH; McBride, J; Shih, HC; Todd, R; Wong, DT | 1 |
Carbonelli, DL; Durán, HA; Molinari de Rey, B; Schwint, A | 1 |
Beltràn, L; DiGiovanni, J; Rho, O; Xian, W | 1 |
Alvarado, ME; Calaf, G; Cox, T; Estrada, S; Russo, J; Tahin, Q | 1 |
Elkind, MM; Shen, Z; Wells, RL | 1 |
Cuthill, S | 1 |
Beittenmiller, H; Esselman, WJ; Gould, MN; Oakley, C; Wang, B; Welsch, CW; Zhai, YF | 1 |
Gill, TJ; Kunz, HW; Lu, D; Melhem, MF | 1 |
Crean, DH; Liebow, C; Mang, TS; Penetrante, RB | 1 |
Matsuoka, K; Nishikawa, T; Nishimura, Y; Okano, H; Tanaka, A; Tsutsui, J; Wada, S; Wato, M | 1 |
Bradlow, HL; Osborne, MP; Suto, A; Telang, NT; Wong, GY | 1 |
Bowden, GT; Han, KA; Kulesz-Martin, MF; Schneider, BL; Schweizer, J; Sutter, C | 1 |
Chiao, PJ; Hittelman, WN; Hong, WK; Sacks, PG; Shin, DM; Shin, HJ; Tainsky, MA | 1 |
Kittrell, FS; Medina, D | 1 |
Christou, M; Jefcoate, CR; Keith, IM; Schroeder, ME; Shen, X | 1 |
Ember, I; Kertai, P; Kiss, A; Kozma, L | 1 |
Fishman, J; Osborne, MP; Telang, NT | 1 |
Herlyn, M; Montone, KT; Nesbit, M; Satyamoorthy, K; Soballe, PW | 1 |
Alitalo, R; Hatva, E; Jalkanen, M; Jeskanen, L; Kaipainen, A; Lymboussaki, A; Stenbäck, F; Västrik, I; Werner, S | 1 |
Hashimura, K; Mori, M; Sumitomo, S | 1 |
Schwartz, JL; Shklar, G | 2 |
Crean, DH; Furukawa, K; Kato, H; Mang, TS; Yamamoto, H | 1 |
Cabrini, RL; Folco, A; Itoiz, ME; Morales, A; Schwint, AE | 1 |
Conti, CJ; Stern, MC | 1 |
Chen, FF; Chen, RM; Jin, YT; Tsai, ST; Wong, TY | 1 |
Iacopino, AM; Miller, EG; Rees, TD; Shih, SD; Wright, JM | 1 |
Alexander, WS; Burgess, AW; Dunn, AR; Fowler, KJ; Grail, D; Hibbs, ML; Mann, GB; Walker, F | 1 |
Katdare, M; Newmark, H; Osborne, MP; Singhal, H; Telang, NT | 1 |
Barton, SL; Burchiel, SW; Ethier, SP; Tannheimer, SL | 1 |
Bélanger, A; Labrie, C; Labrie, F; Luo, S; Sourla, A | 1 |
Benito, N; Gamallo, C; Gandarillas, A; Quintanilla, M; Scholl, FG | 1 |
Aruna, P; Ganesan, S; Vengadesan, N | 1 |
Dhingra, JK; Feld, MS; Itzkan, I; Kabani, S; Manoharan, R; McMillan, K; Shapshay, SM; Zhang, X | 1 |
George, K; Gilliard, G; Megosh, L; O'Brien, TG; Peralta Soler, A | 1 |
Pena, JC; Rudin, CM; Thompson, CB | 1 |
Mäkinen, M; Stenbäck, F | 1 |
Farkash, E; Halpern, M; Megosh, L; O'Brien, TG | 1 |
Furalyov, VA; Kravchenko, IV; Pylev, LN; Vasylieva, LA | 1 |
Heddle, JA | 1 |
Futakuchi, M; Hirose, M; Miki, T; Ozaki, M; Shirai, T; Tanaka, H | 1 |
Bonin, A; Crotty, K; Khalil, M; Menzies, S | 1 |
Ferraris, ME; Fonseca, M; Gendelman, H | 1 |
Schwartz, JL | 1 |
Chatterjee, M; Indira, BN; Karmakar, R; Oinam, S; Roy, A | 1 |
Iida, K; Kato, M; Kurita, K; Tatematsu, M; Yoshida, K | 1 |
Bartorelli, A; Berta, GN; Bosio, A; Bussolati, B; Bussolati, G; Corvetti, G; Di Carlo, F; Ghezzo, F; Guglielmone, R | 1 |
Gurley, KE; Kemp, CJ; Philipp, J; Seidel, K; Vo, K | 1 |
Owens, DM; Smart, RC; Wei, S | 1 |
Chen, J; Han, C; Li, N | 1 |
Bradlow, HL; Guo, L; Mittelman, A; Singhal, H; Tiwari, RK | 1 |
Galfi, M; Gáspár, L; Julesz, J; Khalil, WK; Szalai, G | 1 |
Chen, JK; Ganss, B; Sasaguri, K; Sodek, J | 1 |
Boorman, GA; Haseman, JK; McCormick, DL; Sills, RC; Ward, JM | 1 |
Duesberg, P; Hehlmann, R; Kraemer, A; Li, R; Rasnick, D; Rausch, C; Willer, A; Yerganian, G | 1 |
Alvarado, ME; Calaf, G; Estrad, S; Russo, J; Tait, L | 1 |
Lee, DC; Schroeder, JA | 1 |
Brinkley, BR; Go, C; He, W; Huang, J; Li, P; Wang, XJ; Zhong, L | 1 |
Wang, Y; Zhang, S; Zhou, Y; Zhou, Z | 1 |
Ahmed, A; Hengesteg, A; Robbins, KT; Wani, MK; Yarber, RH | 1 |
Klein-Szanto, A; Zhang, S | 1 |
Hennings, H; Koehler, B; Kulesz-Martin, MF; Yuspa, SH | 1 |
Cao, T; He, W; Myers, TE; Smith, DA; Wang, XJ | 1 |
Chen, XG; Han, R; Li, LN; Li, Y; Yan, CH | 1 |
Asamoto, M; Naito, A; Ochiya, T; Ota, T; Sekiya, T; Terada, M; Toriyama-Baba, H; Tsuda, H | 1 |
Owens, DM; Watt, FM | 1 |
Berns, A; Krimpenfort, P; Loonstra, A; Mooi, WJ; Quon, KC | 1 |
Aguirre, AJ; Bardeesy, N; Carrasco, D; Castrillon, DH; DePinho, RA; Horner, JW; Lee, KH; Sharpless, NE; Wu, EA | 1 |
Fujiki, H; Iida, N; Kishimoto, T; Kurusu, M; Ohshima, S; Okabe, S; Saeki, Y; Suganuma, M | 1 |
Budunova, IV; Gutkind, JS; Jorcano, JL; Larcher, F; Martínez, J; Murga, C; Paramio, JM; Perez, P; Ruiz, S; Santos, M; Segrelles, C; Slaga, TJ | 1 |
Cuendet, M; Fong, HH; Hawthorne, ME; Kardono, LB; Kinghorn, AD; Mehta, RG; Pezzuto, JM; Riswan, S; Su, BN | 1 |
Bowden, T; Finch, S; Joseloff, E | 1 |
Kohno, H; Tanaka, T; Tanino, M; Yanaida, Y | 1 |
Conneely, OM; Gay, J; Hilsenbeck, SG; Medina, D; O'Malley, BW; Shine, HD; Sivaraman, L | 1 |
Courtney, RJ; Flannery, VL; Schaffer, PA | 1 |
Kitano, Y | 1 |
Mondal, S; Sala, M | 1 |
Nishizuka, Y | 1 |
Ekelman, KB; Milo, GE | 1 |
Nandi, S; Richards, J | 1 |
Hillesund, T; Pienta, RJ; Poiley, JA; Raineri, R | 1 |
Chouroulinkov, I; Lasne, C | 1 |
Amer, SM; Boukamp, P; Fusenig, NE; Worst, PK | 1 |
Baker, S; Grover, PL; Marquardt, H; Sims, P; Tierney, B | 2 |
Franks, LM; Summerhayes, IC; Wilson, PD | 1 |
Bapat, CV; Bhat, AV; Gokhale, JA; Rao, KV | 1 |
Franks, LM; Summerhayes, IC | 1 |
Saxholm, HJ | 1 |
Fisher, PB; Goldstein, NI; Weinstein, IB | 1 |
Ludwig, G; Thielmann, HW | 1 |
Christian, ST; Monti, JA; Sarrif, AM; Saxholm, HJ | 1 |
Essex, M; Nelson-Rees, WA; Rhim, JS | 1 |
Dipple, A; Iype, PT; Tomaszewski, JE | 1 |
Reith, A; Saxholm, HJ | 1 |
Bertram, JS | 2 |
Banerjee, MR; Iyer, AP; Kundu, AB; Telang, NT | 1 |
Custer, RP; Dickens, MS; Sorof, S | 1 |
Normann, SJ; Schardt, M; Sorkin, E | 1 |
Perantoni, A; Schwartz, AG | 1 |
Ehemann, V; Goerttler, K; Haag, D; Schlieter, F | 1 |
Stenbäck, F | 1 |
Heidelberger, C; Nowinski, RC; Rapp, UR; Reznikoff, CA | 1 |
Bigner, DD; Cloyd, MW | 1 |
Kaji, H; Rao, P | 1 |
Gullino, PM | 1 |
Medina, D; Pauley, RJ; Socher, SH | 1 |
Ball, JK | 1 |
Brem, SS; Gullino, PM; Medina, D | 1 |
Miyazawa, T; Umeda, M | 1 |
Chouroulinkov, I; Gentil, A; Lasne, C | 2 |
Beesau, O; Chamaillard, L; Hubert-Harbart, M; Levy, S; Markovits, P; Papadopoulo, D | 1 |
Hosick, HL; Starkey, JR | 1 |
Flaks, A; Sims, P | 1 |
Franks, LM; Knowles, MA | 1 |
Goerttler, K; Komitowski, D; Löhrke, H | 1 |
Kobliakov, VA | 1 |
Tsunawaki, A | 1 |
Arnstein, P; Cho, HY; Rhim, JS | 1 |
Black, O; Bockman, DE; Mills, LR; Webster, PD | 1 |
Kennedy, S; Langenbach, R | 1 |
Bulovskaia, LN | 1 |
Blakeslee, J; DiPaolo, JA; Milo, GE; Yohn, DS | 1 |
Curtis, GL; Heidrick, ML; Ryan, WL | 1 |
Marchok, AC; Nettesheim, P; Rhoton, JC | 1 |
Embleton, MJ; Heidelberger, C | 1 |
Jabara, AG; Matthews, JP; Minasian, LC | 1 |
Ahlström, U; Mark, J | 1 |
Olenov, IuM | 1 |
Arnstein, P; Huebner, RJ; Kim, CM; Nelson Ress, WA; Rhim, JS; Weisburger, EK | 1 |
Franks, LM; Hemmings, VJ; Hynes, RO; Pearlstein, E | 1 |
Casto, BC; Dipaolo, JA; Janosko, N; Pieczynski, WJ | 1 |
Grover, PL; Marquardt, H; Sims, P | 1 |
Brankow, DW; Heidelberger, C; Mondal, S | 1 |
Griesemer, RA; Marchok, AC; Nettesheim, P | 1 |
Shklar, G; Sonis, ST | 1 |
Buty, SG; Slaga, TJ; Thompson, S | 1 |
Aspegren, K; Biörklund, A; Tropé, C | 1 |
Clark, WH; Kligman, LH; Min, BH | 1 |
DiPaolo, JA; Popescu, NC | 1 |
Langenbach, R; Malick, LE | 1 |
Aguelon, AM; Nakazawa, H; Yamasaki, H | 1 |
Mesnil, M; Nakazawa, H; Yamasaki, H | 1 |
Kato, R; Wang, JC; Yamamoto, S | 1 |
Bowden, GT; Schneider, BL | 1 |
Chen, CC; Elkind, MM; Wells, RL | 1 |
Bandyopadhyay, AM; Banerjee, MR; Das, SK; Jia, TZ | 1 |
Biswas, DK; Husain, Z; Kwong, YY | 1 |
Bonham, K; Bowden, GT; Krieg, P; Ostrowski, LE | 1 |
Austin, SJ; Beeman, DK; Lasley, JA; Mass, MJ; Schorschinsky, NS | 2 |
Moroco, JR; Polverini, PJ; Solt, DB | 2 |
Aldaz, CM; Bianchi, AB; Conti, CJ | 1 |
Fürstenberger, G; Krieg, P; Marks, F; Schnapke, R; Vogt, I | 1 |
Otsuka, M; Yang, HC | 1 |
Gallagher, GT; Ghiabi, M; Wong, DT | 1 |
Hennings, H | 1 |
Biozzi, G | 1 |
Balmain, A; Bowden, GT; Haddow, S; Jaffe, D; Jonas, D; Quintanilla, M | 1 |
Senger, D; Torsten, U; Weitzel, HK | 1 |
Koszalka, M; Russo, IH; Russo, J | 1 |
Chang, LC; Chou, MY; Gallagher, GT; Wong, DT | 1 |
Belman, S; Bosland, MC; Estensen, RD; Savarese, K; Sellakumar, A | 1 |
Fialkow, PJ; Reddy, AL | 1 |
Chambers, AF; Craig, AM; Denhardt, DT; Edwards, DR; Guo, XJ; Murphy, LC; Parfett, CL; Reid, RE; Waterhouse, P | 1 |
Hosaka, M; Kawamura, K; Mori, M; Murase, N; Takai, Y | 1 |
Harper, JR; Roop, DR; Yuspa, SH | 1 |
Billings, PC; Landolph, JR; Lillehaug, J; Miura, T; Roy-Burman, P; Shuin, T | 1 |
Chang, AL; Gallagher, GT; Gertz, R; Shklar, G; Wong, DT | 1 |
Cheng, CK; Krieg, TM; Mehrel, T; Roop, DR; Yuspa, SH | 1 |
Aldaz, CM; Conti, CJ | 1 |
Baird, WM; Bandyopadhyay, AM; Banerjee, MR; Das, SK; Delp, CR; Mathiesen, M | 1 |
Biswas, DK; Fei, YB; Husain, Z; Polverini, PJ; Roy, S; Solt, DB | 1 |
Miller, DR; Morris, RJ; O'Connell, JF; Patskan, GP; Slaga, TJ; Tacker, K; Viaje, AV | 1 |
Chang, AL; Chiang, T; Chow, P; Gallagher, G; Gertz, R; Matossian, K; McBride, J; Shklar, G; Wong, DT | 1 |
Carter, CA; Ip, C; Ip, MM | 1 |
Arboleda, MJ; Der, CJ; Kimoto, KA; MacDonald, MJ; Ochiai, R; Weissman, BE | 1 |
Athar, M; Bickers, DR; Lloyd, JR; Mukhtar, H | 1 |
Chang, LC; Chou, MY; Chow, P; Gallagher, GT; Matossian, K; McBride, J; Tao, CA; Wong, DT | 1 |
Austin, SJ; Mass, MJ | 1 |
Kandarkar, SV; Potdar, PD; Sirsat, SM | 1 |
Xie, JF; Zhang, KH | 1 |
Indo, K; Miyaji, H | 1 |
Hanausek-Walaszek, M; Lang, RW; Walaszek, Z; Webb, TE | 1 |
Banerjee, MR; Manoharan, K | 1 |
Matsuzawa, A | 1 |
Basolo, F; Bistocchi, M; Sarnelli, R; Squartini, F | 1 |
Cardiff, RD; Faulkin, LJ; Gardner, MB; Malone, RW; Mitchell, DJ; Morris, DW; Strange, R; Young, LJ | 1 |
Kritchevsky, D | 1 |
Breznik, T; Butel, JS; Cohen, JC; Gama-Sosa, MA; Medina, D | 1 |
Billings, P; Kennedy, AR; Messadi, DV; Shklar, G | 1 |
Miao, RM; Miller, A; Reist, EJ; Suk, WA; Tanga, MJ | 1 |
Cheng, HF; Cole, DA; Lindholm, PA; Stevens, RH | 1 |
Bock, KW; Fusenig, NE; Irmscher, G; Lilienblum, W | 1 |
Barbacid, M | 1 |
Fukushima, S; Hirose, M; Inoue, T; Ito, N; Masuda, A | 1 |
Anderson, TM; Cameron, JW; Hatch, GG; Kouri, RE; Lubet, RA; Nims, RW; Putman, DL; Schechtman, LM; Spalding, JW; Tennant, RW | 1 |
Blumenson, L; Kulesz-Martin, M; Lisafeld, B | 1 |
Mehta, RG; Moon, RC | 1 |
Bower, EA; Kaji, H | 1 |
Giles, A; Kornhauser, A; Wamer, W | 1 |
Blask, DE; Hill, SM; Massa, JS; Orstead, KM | 1 |
Hawrylewicz, EJ | 1 |
Telang, NT | 1 |
Hashimoto, Y; Shudo, K | 1 |
Asch, BB; Bartley, JC; Guzman, RC; Imagawa, W; Nandi, S; Osborn, RC | 1 |
Cardiff, RD; Dandekar, S; Sukumar, S; Young, LJ; Zarbl, H | 1 |
Huh, N; Kuroki, T | 1 |
Marchok, AC; Martin, DH | 1 |
Russo, IH; Russo, J | 1 |
Hendrix, MJ; Huerta, CC; Persky, B | 1 |
Lahiri, P; Lahiri, T | 1 |
Biswas, DK; Wong, DT | 1 |
Kamino, H; Leon, J; Pellicer, A; Steinberg, JJ | 1 |
Frederick, J; Reina, D; Russo, IH; Russo, J | 1 |
Heideman, KA; Lin, LM; Toto, PD | 1 |
Baba, M; Bonfil, RD; Klein-Szanto, AJ; Obara, T; Resau, J; Trump, BF; Yamaguchi, Y | 1 |
de Campos Vidal, B; Russo, J | 1 |
Biswas, DK; Fei, Y; Polverini, PJ; Ray, S; Solt, DB | 1 |
Brookes, P; Cooper, CS; Ellis, MV; Gardner, E; Summerhayes, IC; Warren, W | 1 |
Aalfs, KK; DiGiovanni, J; Fisher, EP; Prichett, WP | 1 |
Hennings, H; Yuspa, SH | 1 |
Furuya, K; Williams, GM | 1 |
Fürstenberger, G; Kinzel, V; Marks, F; Schwarz, M | 1 |
Aboud, M; Hassan, Y; Huleihel, M; Priel, E; Wolfson, M | 1 |
Codd, RM; Gohari, K; White, FH | 1 |
Levina, NV; Mekler, LB; Skorikova, AS; Skurkovich, SV | 1 |
29 review(s) available for 9,10-dimethyl-1,2-benzanthracene and Cell Transformation, Neoplastic
Article | Year |
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[Chemoprevention of carcinogenesis].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cyclic AMP; DNA, Neoplasm; Glutathione Transferase; Humans; Interferons; Mice; Neoplasms; Oncogenes; Phenobarbital; Protease Inhibitors; Rats; Selenium; Tryptophan Oxygenase; Vitamin A | 1983 |
Molecular and cellular basis of the mammary gland susceptibility to carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Binding Sites; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA Repair; Female; Hormones; In Vitro Techniques; Kinetics; Mammary Neoplasms, Experimental; Polycyclic Compounds; Rats; Rats, Inbred Strains | 1983 |
Basis of cellular autonomy in the susceptibility to carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Cycle; Cell Transformation, Neoplastic; Chorionic Gonadotropin; DNA; DNA Repair; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1983 |
Effect of conjugated linoleic acid on carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimutagenic Agents; Cell Transformation, Neoplastic; Female; Gastrointestinal Neoplasms; Linoleic Acids; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred ICR; Rats; Rats, Inbred F344; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
Role of the epidermal growth factor receptor and transforming growth factor alpha in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Disease Progression; ErbB Receptors; Mice; Models, Biological; Papilloma; Phorbol Esters; Precancerous Conditions; Skin Neoplasms; Transforming Growth Factor alpha | 1994 |
Cellular epigenetics and the origin of cancer.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Culture Media; Genes, Tumor Suppressor; Growth Substances; Mice; Models, Biological; Neoplasms; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Oncogenes; Phenotype; Rats; Selection, Genetic | 1994 |
The role of estrogen in mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast; Breast Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Epithelium; Estradiol; Female; Humans; Mammary Glands, Animal; Menstrual Cycle; Mice; Mice, Inbred Strains; Organ Culture Techniques; Receptors, Estrogen; Risk Factors; Transcription Factors; United States | 1995 |
Genetic susceptibility to tumor progression in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Crosses, Genetic; Disease Progression; Disease Susceptibility; Hyperplasia; Mice; Mice, Inbred SENCAR; Mice, Inbred Strains; Papilloma; Precancerous Conditions; Skin; Skin Neoplasms | 1996 |
Insights into the physiology of TGF alpha and signaling through the EGF receptor revealed by gene targeting and acts of nature.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Epidermal Growth Factor; ErbB Receptors; Gene Targeting; Hair; Mice; Mice, Knockout; Mice, Mutant Strains; Multigene Family; Mutagenesis, Insertional; Papilloma; Recombination, Genetic; Signal Transduction; Skin Neoplasms; Transforming Growth Factor alpha; Vibrissae; Wound Healing | 1994 |
The use of transgenic animals in research.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Animals, Genetically Modified; Carcinogens, Environmental; Cell Transformation, Neoplastic; Codon; Genes, ras; Liver; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Knockout; Mitosis; Mutagenesis; Mutagenicity Tests; Mutagens; Neoplasms; Polymerase Chain Reaction; Rats; Sensitivity and Specificity; Transgenes | 1998 |
Magnetic fields and mammary cancer in rodents: a critical review and evaluation of published literature.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Biological Assay; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Disease Models, Animal; Electromagnetic Fields; Female; Fibroadenoma; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Rats | 2000 |
Transgenic mice reveal roles for TGFalpha and EGF receptor in mammary gland development and neoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Transformation, Neoplastic; ErbB Receptors; Female; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Pregnancy; Transforming Growth Factor alpha | 1997 |
Keratinization of human epidermal cells in culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acids; Antigens; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Culture Techniques; DNA; Epidermal Cells; Epidermis; Humans; Immunoglobulin G; Keratins; Melanocytes; Microscopy, Electron | 1979 |
[Transformations of polycyclic aromatic hydrocarbons in the cell].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Carcinogens, Environmental; Cell Transformation, Neoplastic; DNA; Drug Interactions; Endoplasmic Reticulum; Enzyme Activation; Epoxy Compounds; Free Radicals; Humans; Methylation; Microsomes; Oxidation-Reduction; Phenols; Polycyclic Compounds | 1977 |
[Securing the primary effect in experiments with chemical carcinogens].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Carbohydrate Metabolism; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chromosomes; DNA; Embryo, Mammalian; Embryo, Nonmammalian; Genes; Genes, Regulator; Mutation; Neoplasm Proteins; Neoplasms; Neoplasms, Experimental; Organ Culture Techniques; p-Dimethylaminoazobenzene; Precancerous Conditions; RNA, Neoplasm | 1975 |
Relationship of chromosome changes to neoplastic cell transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Azure Stains; Carcinogens; Cell Line; Cell Nucleolus; Cell Transformation, Neoplastic; Chromatids; Chromosomes; Humans; Karyotyping; Methylnitronitrosoguanidine; Neoplasms; Transformation, Genetic; Trisomy | 1976 |
Interaction and distinction of genotoxic and non-genotoxic events in carcinogenesis.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Humans; Mice; Mutagens; Neoplasms; Risk Factors; Tetradecanoylphorbol Acetate | 1992 |
Selective pressures and ras activation in carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Genes, ras; Mice; Mutation; Rats; Selection, Genetic; Tumor Cells, Cultured | 1992 |
Differential gene expression during tumor promotion and progression in the mouse skin model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA; Gene Expression Regulation, Neoplastic; Matrix Metalloproteinase 3; Metalloendopeptidases; Methylnitronitrosoguanidine; Mice; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms, Multiple Primary; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ubiquitins | 1991 |
The premalignant nature of mouse skin papillomas: histopathologic, cytogenetic, and biochemical evidence.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; Karyotyping; Keratins; Mice; Papilloma; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Investigations of multistage carcinogenesis: applications of in vitro-in vivo studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Methylnitronitrosoguanidine; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
[The role of hormones in neoplastic transformation].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Epidermal Growth Factor; Hormones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Prolactin; Receptors, Cell Surface; Thyrotropin; Urethane | 1986 |
Early pathologic changes in experimental and human breast cancer: facts and comments.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast; Breast Neoplasms; Cell Transformation, Neoplastic; Female; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methylcholanthrene; Mice; Mice, Inbred BALB C; Models, Biological; Mosaicism; Precancerous Conditions; Pregnancy | 1986 |
Fat, calories and fiber.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Colon; Dietary Fats; Dietary Fiber; Energy Intake; Energy Metabolism; Feces; Food Deprivation; Neoplasms, Experimental; Nutritional Requirements | 1986 |
Oncogenes and human cancer: cause or consequence?
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Chromosome Mapping; Gene Expression Regulation; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Neoplasms; Neoplasms, Experimental; Oncogenes; Proto-Oncogenes; Rats; Retroviridae; Skin Neoplasms | 1986 |
Fat-protein interaction, defined 2-generation studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Cell Transformation, Neoplastic; Cocarcinogenesis; Dietary Fats; Dietary Proteins; Disease Models, Animal; Eating; Epidemiologic Methods; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Prolactin; Thymidine | 1986 |
Fatty acid-induced modifications of mouse mammary epithelium as studied in an organ and cell culture system.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Fatty Acids; Mammary Glands, Animal; Mice; Organ Culture Techniques | 1986 |
[Oncogenes, their implications in cell growth, differentiation and carcinogenesis].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cell Transformation, Viral; Epidermal Growth Factor; Genes, Viral; Humans; Mammary Neoplasms, Experimental; Neoplasms; Platelet-Derived Growth Factor; Retroviridae; Transfection; Urinary Bladder Neoplasms | 1987 |
From pathogenesis to hormone prevention of mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Contraceptive Agents, Female; Disease Models, Animal; Disease Susceptibility; Female; Hormones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Placental Hormones; Pregnancy | 1986 |
489 other study(ies) available for 9,10-dimethyl-1,2-benzanthracene and Cell Transformation, Neoplastic
Article | Year |
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Effects of Pubertal Exposure to Butyl Benzyl Phthalate, Perfluorooctanoic Acid, and Zeranol on Mammary Gland Development and Tumorigenesis in Rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Caprylates; Carcinogenesis; Cell Transformation, Neoplastic; Endocrine Disruptors; Female; Fluorocarbons; Hormones; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Phthalic Acids; Rats; Rats, Sprague-Dawley; Zeranol | 2022 |
Protective Effects of Pelargonidin against DMBA-Induced Mammary Tumorigenesis in BALB/c Mice through Reduced Oxidative Stress and Lipid Anomalies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Lipids; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Oxidative Stress; Tamoxifen | 2023 |
Nobiletin Attenuates Cell Proliferation by Modulating the Activating Protein-1 Signaling Pathway in 7,12-Dimethylbenz[a]anthracene-Induced Mammary Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Breast Neoplasms; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Female; Flavones; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Signal Transduction; Transcription Factor AP-1 | 2020 |
Integrin α3β1 Is a Key Regulator of Several Protumorigenic Pathways during Skin Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Epidermis; Humans; Integrin alpha3beta1; Kalinin; Keratinocytes; Mice; Neoplasms, Experimental; Signal Transduction; Skin Neoplasms; Spheroids, Cellular; Tetradecanoylphorbol Acetate; Tetraspanin 24 | 2021 |
Inhibition of Neoplastic Transformation and Chemically-Induced Skin Hyperplasia in Mice by Traditional Chinese Medicinal Formula Si-Wu-Tang.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carrier Proteins; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Damage; Drugs, Chinese Herbal; Female; Gene Expression Regulation; Genes, Reporter; Hyperplasia; Mice; Mice, Inbred SENCAR; NF-E2-Related Factor 2; NF-kappa B; Skin; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2017 |
E1a is an exogenous in vivo tumour suppressor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenovirus E1A Proteins; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Female; HCT116 Cells; Humans; Melanoma, Experimental; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Burden; Tumor Suppressor Proteins | 2017 |
Anti-Inflammatory Mechanism Involved in Pomegranate-Mediated Prevention of Breast Cancer: the Role of NF-κB and Nrf2 Signaling Pathways.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Apoptosis; Cell Transformation, Neoplastic; Cyclooxygenase 2; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; I-kappa B Kinase; Lythraceae; Mammary Neoplasms, Experimental; NF-E2-Related Factor 2; NF-kappa B; Plant Preparations; Rats; Signal Transduction | 2017 |
Allyl isothiocyanate, a potent chemopreventive agent targets AhR/Nrf2 signaling pathway in chemically induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Transformation, Neoplastic; Female; Isothiocyanates; Mammary Neoplasms, Experimental; Neoplasm Proteins; NF-E2-Related Factor 2; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Signal Transduction | 2018 |
PKK deletion in basal keratinocytes promotes tumorigenesis after chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Genes, Tumor Suppressor; Humans; Keratinocytes; Mice; Mice, Knockout; Protein Serine-Threonine Kinases; Pyridines; Signal Transduction; Skin Neoplasms | 2018 |
Multicolour lineage tracing reveals clonal dynamics of squamous carcinoma evolution from initiation to metastasis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Lineage; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Clonal Evolution; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Genetic Predisposition to Disease; Male; Mice, Transgenic; Mutation; Neoplasms, Experimental; Phenotype; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Burden | 2018 |
TRP63/TP63 loss accelerates skin tumorigenesis through activation of Wnt/β-catenin signaling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Mice, Knockout; Mice, Nude; Phosphoproteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Trans-Activators; Transcription Factors; Tumor Burden; Tumor Suppressor Proteins; Wnt Signaling Pathway | 2018 |
DMBA promotes ErbB2‑mediated carcinogenesis via ErbB2 and estrogen receptor pathway activation and genomic instability.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Female; Genomic Instability; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Receptor, ErbB-2; Receptors, Estrogen; Tumor Cells, Cultured | 2018 |
C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genes, Lethal; Keratinocytes; Mice; Mice, Knockout; ras Proteins; Receptors, Death Domain; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2018 |
Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Bone Morphogenetic Protein 5; Cell Movement; Cell Plasticity; Cell Transformation, Neoplastic; Coculture Techniques; Epithelial Cells; Female; Hair Follicle; HMGB1 Protein; Keratinocytes; Keratins; Male; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Papilloma; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2018 |
Preventive effect of D-carvone during DMBA induced mouse skin tumorigenesis by modulating xenobiotic metabolism and induction of apoptotic events.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinogenesis; Carcinogens; Cell Transformation, Neoplastic; Cyclohexane Monoterpenes; Dose-Response Relationship, Drug; Male; Mice; Monoterpenes; Random Allocation; Skin Neoplasms; Treatment Outcome; Xenobiotics | 2019 |
[Role of clock proteins in skin carcinogenesis in 14-month-old SHR mice maintained under disrupted light regimen].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; ARNTL Transcription Factors; Cell Transformation, Neoplastic; CLOCK Proteins; Cryptochromes; Gene Expression Regulation, Neoplastic; Lighting; Male; Mice; Neoplasm Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
Synergistic efficacy of RLIP inhibition and 2'-hydroxyflavanone against DMBA-induced mammary carcinogenesis in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; CDC2 Protein Kinase; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Flavanones; GTPase-Activating Proteins; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred SENCAR; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt | 2019 |
[Anticarcinogenic effect of potassium salts of glucaric and glucuronic acid in induced models of cervical and esophageal tumors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Calcium Compounds; Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; Disease Models, Animal; Esophageal Neoplasms; Female; Glucaric Acid; Glucuronic Acid; Mice; Potassium Compounds; Salts; Uterine Cervical Neoplasms | 2012 |
Saffron reduction of 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Chemoprevention; Cricetinae; Crocus; Hyperplasia; Lipid Peroxidation; Male; Mouth Mucosa; Mouth Neoplasms; Plant Preparations | 2013 |
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Female; Genes, ras; Keratinocytes; Male; Mice; Mice, Knockout; Nuclear Proteins; Oncogene Protein p21(ras); Protein Inhibitors of Activated STAT; Proto-Oncogene Proteins c-myc; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases | 2013 |
Modulatory effects of Azadirachta indica leaf extract on cutaneous and hepatic biochemical status during promotion phase of DMBA/TPA-induced skin tumorigenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antioxidants; Azadirachta; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; Cytochromes b5; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Lipid Peroxidation; Liver; Male; Mice; Micronucleus Tests; Neoplasms, Experimental; Phytotherapy; Plant Extracts; Plant Leaves; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Xenobiotics | 2013 |
Isolation of a quinone-rich fraction from Ardisia crispa roots and its attenuating effects on murine skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ardisia; Benzoquinones; Carcinogens; Cell Transformation, Neoplastic; Female; Gas Chromatography-Mass Spectrometry; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Skin Neoplasms | 2013 |
Fermented Prunus mume with probiotics inhibits 7,12-dimethylbenz[a]anthracene and 12-o-tetradecanoyl phorbol-13-acetate induced skin carcinogenesis through alleviation of oxidative stress.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antioxidants; Cell Proliferation; Cell Transformation, Neoplastic; Diet; Female; Fermentation; Lipid Peroxidation; Mice; Mice, Inbred BALB C; Oxidative Stress; Plant Preparations; Probiotics; Prunus; Skin; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2013 |
Protective effects of [6]-paradol on histological lesions and immunohistochemical gene expression in DMBA induced hamster buccal pouch carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Caspase 3; Cell Proliferation; Cell Transformation, Neoplastic; Cheek; Cricetinae; Guaiacol; Immunoenzyme Techniques; Ketones; Male; Mesocricetus; Mouth Neoplasms; Proto-Oncogene Proteins c-bcl-2; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Zingiber officinale | 2013 |
Characterization of synergistic anti-cancer effects of docosahexaenoic acid and curcumin on DMBA-induced mammary tumorigenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Transformation, Neoplastic; Cluster Analysis; Curcumin; Diet; Docosahexaenoic Acids; Drug Synergism; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Inhibitor of Apoptosis Proteins; Mammary Neoplasms, Experimental; Mice; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Serpins; Survivin; Tumor Burden; Tumor Microenvironment | 2013 |
Simultaneous disruption of estrogen receptor and Wnt/β-catenin signaling is involved in methyl amooranin-mediated chemoprevention of mammary gland carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Catenin; Carcinogenesis; Cell Transformation, Neoplastic; Chemoprevention; Cyclin D1; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Kidney; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Triterpenes; Wnt Proteins; Wnt Signaling Pathway | 2013 |
Genome-wide screening of aberrant DNA methylation which associated with gene expression in mouse skin cancers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Azacitidine; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred C57BL; Papilloma; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-2 | 2015 |
Exposure to excess estradiol or leptin during pregnancy increases mammary cancer risk and prevents parity-induced protective genomic changes in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Biomarkers, Tumor; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Estradiol; Estrogens; Female; Gene Expression Profiling; Genomics; Immunoenzyme Techniques; Leptin; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Oligonucleotide Array Sequence Analysis; Parity; Pregnancy; Pregnancy Complications, Neoplastic; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger | 2013 |
Higher incidence of lung adenocarcinomas induced by DMBA in connexin 43 heterozygous knockout mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogens; Cell Transformation, Neoplastic; Connexin 43; Lung Neoplasms; Mice; Mice, Knockout; Neoplasms, Experimental | 2013 |
Chemoprevention of oral cancer by lyophilized strawberries.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cricetinae; Fragaria; Freeze Drying; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2013 |
Anti-cell proliferative and anti-angiogenic potential of andrographolide during 7,12- dimethylbenz(a)anthracene induced hamster buccal pouch carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Apoptosis; Carcinogens; Carcinoma, Squamous Cell; Cell Proliferation; Cell Transformation, Neoplastic; Cricetinae; Cyclin D1; Diterpenes; Immunoenzyme Techniques; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Neoplasms, Experimental; Neovascularization, Pathologic; Proliferating Cell Nuclear Antigen; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2013 |
Extraction optimization of Tinospora cordifolia and assessment of the anticancer activity of its alkaloid palmatine.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alanine Transaminase; Animals; Antineoplastic Agents; Aspartate Aminotransferases; Berberine Alkaloids; Carcinogens; Catalase; Cell Transformation, Neoplastic; Chemoprevention; Croton Oil; Disease Models, Animal; DNA Damage; Glutathione; Mice; Oxidative Stress; Plant Extracts; Skin Neoplasms; Superoxide Dismutase; Tinospora | 2013 |
S100A9 has a protective role in inflammation-induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calgranulin A; Calgranulin B; Carcinogenesis; Cell Transformation, Neoplastic; Dimerization; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Inflammation; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2014 |
Tumor promoter-induced sulfiredoxin is required for mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Gene Expression Regulation; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2014 |
Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chromatin Immunoprecipitation; Dermis; Female; Fibroblasts; Humans; Immunoenzyme Techniques; Keratinocytes; Mice; Mice, Knockout; PPAR delta; PPAR-beta; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Skin Neoplasms | 2014 |
Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Communication; Cell Differentiation; Cell Transformation, Neoplastic; Cytokines; Dermatitis, Atopic; Disease Models, Animal; Epidermis; Keratinocytes; Membrane Proteins; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; NK Cell Lectin-Like Receptor Subfamily K; Papilloma; Permeability; Plakins; Protein Precursors; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin; Time Factors | 2014 |
MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cell Transformation, Viral; Endonucleases; Female; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; HEK293 Cells; Humans; Mammary Glands, Animal; Mammary Tumor Virus, Mouse; Medroxyprogesterone Acetate; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neoplasm Invasiveness; Neoplastic Stem Cells; Nuclear Proteins; Phenotype; Protein Binding; RNA Interference; RNA-Binding Proteins; Time Factors; Transfection; Tumor Cells, Cultured | 2014 |
Meis1 regulates epidermal stem cells and is required for skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult Stem Cells; Animals; Carcinogens; Carcinoma; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Gene Expression Regulation, Neoplastic; Hair Follicle; Homeodomain Proteins; Keratinocytes; Mice; Mice, Transgenic; Multipotent Stem Cells; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Comparison of dermal tumor promotion activity of cigarette smoke condensate from prototype (heated) cigarette and reference (combusted) cigarette in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred SENCAR; Organ Size; Skin; Skin Neoplasms; Smoking; Tobacco Products | 2014 |
Chemopreventive activity of turmeric essential oil and possible mechanisms of action.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Carcinogens; Cell Transformation, Neoplastic; Chemoprevention; Croton Oil; Curcuma; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Male; Mice; Mice, Inbred BALB C; Mutagenicity Tests; Mutagens; Oils, Volatile; Papilloma; Plant Extracts; Rats; Rats, Wistar; Skin; Skin Neoplasms | 2014 |
Preventive effects of probiotic bacteria Lactobacillus plantarum and dietary fiber in chemically-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cytokines; Diet; Dietary Fiber; Disease Models, Animal; Female; Inulin; Lactobacillus plantarum; Mammary Neoplasms, Experimental; Neoplasm Invasiveness; Neoplasm Staging; Probiotics; Rats; T-Lymphocyte Subsets | 2014 |
Mechanisms of chemical cooperative carcinogenesis by epidermal Langerhans cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cytochrome P-450 CYP1B1; Disease Models, Animal; Keratinocytes; Langerhans Cells; Mice; Mice, Knockout; Mutagens; Skin Neoplasms | 2015 |
Interfering with stem cell-specific gatekeeper functions controls tumour initiation and malignant progression of skin tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Apoptosis; Carcinogenesis; Carcinogens; Cell Lineage; Cell Proliferation; Cell Separation; Cell Transformation, Neoplastic; Crosses, Genetic; Disease Progression; DNA Damage; Epidermis; Flow Cytometry; Humans; Lymphoid Enhancer-Binding Factor 1; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Phenotype; Sebaceous Gland Neoplasms; Skin Neoplasms; Stem Cells; Tumor Suppressor Protein p53; Ultraviolet Rays | 2015 |
Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Carrier Proteins; Caspase 3; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Chemoprevention; Keratinocytes; Mechanistic Target of Rapamycin Complex 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Multiprotein Complexes; Proto-Oncogene Proteins c-akt; Rapamycin-Insensitive Companion of mTOR Protein; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Ultraviolet Rays | 2015 |
Altered telomere homeostasis and resistance to skin carcinogenesis in Suv39h1 transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromatin Assembly and Disassembly; Chromosomal Proteins, Non-Histone; Epidermis; Female; Histones; Humans; Male; Methylation; Methyltransferases; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Mutation; ras Proteins; Repressor Proteins; Skin Neoplasms; Telomere; Telomere Homeostasis; Telomere Shortening | 2015 |
Native fluorescence spectroscopic characterization of DMBA induced carcinogenesis in mice skin for the early detection of tissue transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Cell Transformation, Neoplastic; Female; Male; Mice; Porphyrins; Skin; Spectrometry, Fluorescence; Time Factors | 2015 |
Shikonin Suppresses Skin Carcinogenesis via Inhibiting Cell Proliferation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Activating Transcription Factor 2; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinogens; Carrier Proteins; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase 4; Epidermis; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Mice; Mice, Inbred DBA; Naphthoquinones; Proto-Oncogene Proteins c-fos; Pyridines; Signal Transduction; Skin Neoplasms; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Transcriptional Activation | 2015 |
Establishment of a new OSCC cell line derived from OLK and identification of malignant transformation-related proteins by differential proteomics approach.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Apoptosis; Benzo(a)pyrene; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation; Humans; Leukoplakia, Oral; Mouth Neoplasms; Neoplasm Proteins; Proteomics | 2015 |
Raman Spectroscopy of Experimental Oral Carcinogenesis: Study on Sequential Cancer Progression in Hamster Buccal Pouch Model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biopsy; Cell Transformation, Neoplastic; Cricetinae; Disease Models, Animal; Male; Mouth Mucosa; Mouth Neoplasms; Principal Component Analysis; Spectrum Analysis, Raman; Time Factors | 2016 |
Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Carcinoma, Verrucous; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; Disease Progression; DNA Transposable Elements; Female; Humans; Mice; Mice, Transgenic; Mouth Neoplasms; Mutagenesis, Insertional; Neoplasm Invasiveness; Oncogenes; Papilloma; Papillomaviridae; Receptor, Notch1; Skin Neoplasms; Specific Pathogen-Free Organisms; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Virus Infections; Uterine Cervical Neoplasms | 2015 |
Cx26 knockout predisposes the mammary gland to primary mammary tumors in a DMBA-induced mouse model of breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Connexin 26; Connexins; Disease Models, Animal; Female; Fluorescent Antibody Technique; Humans; Integrases; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Knockout | 2015 |
Low dose triterpene-quinone fraction from Ardisia crispa root precludes chemical-induced mouse skin tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Ardisia; Cell Transformation, Neoplastic; Chemical Fractionation; Chemoprevention; Curcumin; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Male; Mice; Mice, Inbred ICR; Plant Extracts; Plant Roots; Quinones; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2015 |
Mechanism of Breast Cancer Preventive Action of Pomegranate: Disruption of Estrogen Receptor and Wnt/β-Catenin Signaling Pathways.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; beta Catenin; Breast Neoplasms; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Down-Regulation; Estrogen Receptor alpha; Female; Lythraceae; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Wnt Proteins; Wnt Signaling Pathway | 2015 |
Marginal zinc intake reduces the protective effect of lactation on mammary gland carcinogenesis in a DMBA-induced tumor model in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Breast Neoplasms; Carcinogenesis; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Female; Humans; Lactation; Mammary Glands, Animal; Mice; Oxidative Stress; Peroxiredoxins; Tumor Suppressor Protein p53; Zinc | 2016 |
Taurine Attenuates Dimethylbenz[a]anthracene-induced Breast Tumorigenesis in Rats: A Plasma Metabolomic Study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Female; Gas Chromatography-Mass Spectrometry; Mammary Neoplasms, Experimental; Metabolomics; Plasma; Rats; Rats, Sprague-Dawley; Taurine | 2016 |
Attenuation of DMBA/croton oil induced mouse skin papilloma by Apodytes dimidiata mediated by its antioxidant and antimutagenic potential.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Antioxidants; Catalase; Cell Transformation, Neoplastic; Croton Oil; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Glutathione; Magnoliopsida; Male; Methanol; Mice, Inbred BALB C; Mutation; Oxidative Stress; Papilloma; Phytotherapy; Plant Extracts; Plant Leaves; Plants, Medicinal; Salmonella typhimurium; Skin Neoplasms; Sodium Fluoride; Solvents; Superoxide Dismutase; Time Factors | 2016 |
DMBA induced mouse mammary tumors display high incidence of activating Pik3caH1047 and loss of function Pten mutations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Class I Phosphatidylinositol 3-Kinases; DNA Mutational Analysis; Exome Sequencing; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice, Inbred C57BL; Mice, Inbred DBA; Mutation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; RANK Ligand; Sequence Analysis, RNA; Time Factors; Transcriptome | 2016 |
Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bile Duct Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Hyperplasia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphoproteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trans-Activators | 2017 |
Suppression of skin tumorigenesis in CD109-deficient mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; DNA Damage; Genes, ras; Genetic Predisposition to Disease; Keratinocytes; Mice, Knockout; Mutation; Neoplasm Proteins; NF-E2-Related Factor 2; Papilloma; Phenotype; Phosphorylation; Signal Transduction; Skin Neoplasms; Smad2 Protein; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta1 | 2016 |
CDK2 activation in mouse epidermis induces keratinocyte proliferation but does not affect skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Enzyme Activation; Epidermis; Keratinocytes; Mice; Mice, Transgenic; Mutation; Skin Neoplasms | 2008 |
Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cell Transformation, Neoplastic; DNA Damage; Gene Deletion; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Keratinocytes; Mice; Mutagens; Skin | 2008 |
Graph models for phenotype and genotype association between oral mucosa and submandibular gland tumorigenesis in rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cyclin D1; DNA; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Linear Models; Male; Markov Chains; Models, Statistical; Mouth Mucosa; Neoplasms, Experimental; Normal Distribution; Rats; Rats, Wistar; Submandibular Gland; Submandibular Gland Neoplasms; Tumor Suppressor Protein p53 | 2009 |
Promotion of mouse two-stage skin carcinogenesis by diacylglycerol-rich edible oil.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Diglycerides; Fatty Acids; Female; Fluocinolone Acetonide; Linoleic Acid; Mice; Oils; Oleic Acid; Protein Kinase C; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Inducible cutaneous inflammation reveals a protumorigenic role for keratinocyte CXCR2 in skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Drug Eruptions; Enzyme Activation; Female; Hair Follicle; HeLa Cells; Humans; Keratinocytes; Ligands; Male; Mice; Neutrophils; Protein Kinase C-alpha; Receptors, Interleukin-8B; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Effects of thalidomide on DMBA-induced oral carcinogenesis in hamster with respect to angiogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Chemoprevention; Cricetinae; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Neoplasms, Experimental; Neovascularization, Pathologic; Precancerous Conditions; RNA, Messenger; Thalidomide; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2009 |
Epigenetic therapy using the histone deacetylase inhibitor for increasing therapeutic gain in oral cancer: prevention of radiation-induced oral mucositis and inhibition of chemical-induced oral carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylation; Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA Damage; DNA Repair; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Immunoenzyme Techniques; Male; Mesocricetus; Mouth Neoplasms; Phenylbutyrates; Rad51 Recombinase; Radiation Injuries; Radiation Tolerance; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomatitis; Xenograft Model Antitumor Assays | 2009 |
Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Genotype; Hyperplasia; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mice, Knockout; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oncogene Protein v-akt; Papilloma; Phosphorylation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression; Immunohistochemistry; MAP Kinase Kinase Kinases; Mice; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins B-raf; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 2009 |
The expression profile of microRNAs in a model of 7,12-dimethyl-benz[a]anthrance-induced oral carcinogenesis in Syrian hamster.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cricetinae; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Male; Mesocricetus; MicroRNAs; Mouth Neoplasms | 2009 |
The genotoxic air pollutant 3-nitrobenzanthrone and its reactive metabolite N-hydroxy-3-aminobenzanthrone lack initiating and complete carcinogenic activity in NMRI mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Air Pollutants; Animals; Benz(a)Anthracenes; Carcinogens; Cell Transformation, Neoplastic; DNA Adducts; DNA Damage; Epidermis; Female; Mice; Skin; Skin Neoplasms; Vehicle Emissions | 2009 |
SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Blood Vessels; Carcinogens; Cell Transformation, Neoplastic; Female; Genotype; Immunohistochemistry; Intestinal Polyps; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Neoplasms, Experimental; NIH 3T3 Cells; Resveratrol; Sirtuin 1; Sirtuins; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Transfection | 2009 |
Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminolevulinic Acid; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Kaplan-Meier Estimate; Mice; Mice, Inbred Strains; Papilloma; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Targeted disruption of stat3 reveals a major role for follicular stem cells in skin tumor initiation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Transformation, Neoplastic; Genes, ras; Keratinocytes; Mice; Mice, Transgenic; Mifepristone; Mutation; Skin Neoplasms; STAT3 Transcription Factor; Stem Cells | 2009 |
A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Animals; Aurora Kinase A; Aurora Kinases; Carcinoma, Squamous Cell; Cell Death; Cell Transformation, Neoplastic; Genomic Instability; Humans; Keratinocytes; Mice; Mice, Transgenic; Papilloma; Protein Serine-Threonine Kinases; Skin Neoplasms; Spindle Apparatus | 2009 |
Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch by topical application of resveratrol complexed with 2-hydroxypropyl-beta-cyclodextrin.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; beta-Cyclodextrins; Carcinogens; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Transformation, Neoplastic; Cheek; Cricetinae; Drug Combinations; Mesocricetus; Mouth Neoplasms; Pharmaceutical Vehicles; Resveratrol; Stilbenes | 2010 |
Elevated phosphate activates N-ras and promotes cell transformation and skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Chromatin Immunoprecipitation; Cyclooxygenase 2; Electrophoretic Mobility Shift Assay; Epidermis; Female; Genes, ras; Luciferases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteopontin; Papilloma; Parathyroid Hormone; Phosphates; Phosphorus, Dietary; Proto-Oncogene Proteins c-fos; Skin Neoplasms; Transcription Factor AP-1; Transfection | 2010 |
Chemopreventive activities of etodolac and oxyphenbutazone against mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Etodolac; Mice; Oxyphenbutazone; Skin Neoplasms | 2010 |
Eugenol restricts DMBA croton oil induced skin carcinogenesis in mice: downregulation of c-Myc and H-ras, and activation of p53 dependent apoptotic pathway.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Transformation, Neoplastic; Croton Oil; Down-Regulation; Eugenol; Female; Genes, myc; Genes, p53; Genes, ras; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Skin Neoplasms; Up-Regulation | 2010 |
Evaluation of diuron (3-[3,4-dichlorophenyl]-1,1-dimethyl urea) in a two-stage mouse skin carcinogenesis assay.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Diuron; Female; Herbicides; Mice; Pyridines; Skin; Skin Neoplasms; Solvents | 2010 |
The mitogen-activated protein kinase kinase 4 has a pro-oncogenic role in skin cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Enzyme Activation; Female; Genes, ras; Inbreeding; Male; MAP Kinase Kinase 4; Mice; Skin; Skin Neoplasms | 2010 |
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Epithelial Cells; Female; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Invasiveness; Precancerous Conditions; Progesterone; Progestins; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B | 2010 |
Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Cycle; Cell Transformation, Neoplastic; Extracellular Signal-Regulated MAP Kinases; Humans; Inflammation; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; Phosphorylation; ras Proteins; Signal Transduction; Tetradecanoylphorbol Acetate | 2010 |
A mouse model for human anal cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anus Neoplasms; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Humans; Immunoenzyme Techniques; Immunoprecipitation; Male; Mice; Mice, Transgenic; Oncogene Proteins, Viral; Papillomaviridae; Papillomavirus E7 Proteins; Phenotype; Repressor Proteins | 2010 |
Intrinsic cooperation between p16INK4a and p21Waf1/Cip1 in the onset of cellular senescence and tumor suppression in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Embryo, Mammalian; Fibroblasts; Histones; Mice; Mice, Inbred C57BL; Mice, Knockout; Octamer Transcription Factor-3; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
Elimination of deleterious effects of DMBA-induced skin carcinogenesis in mice by Syzygium cumini seed extract.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Catalase; Cell Transformation, Neoplastic; Chemoprevention; Croton Oil; Glutathione; Herbal Medicine; Lipid Peroxidation; Liver; Male; Mice; Papilloma; Plant Extracts; Seeds; Skin; Skin Neoplasms; Superoxide Dismutase; Syzygium | 2011 |
Rapamycin inhibits anal carcinogenesis in two preclinical animal models.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibiotics, Antineoplastic; Anus Neoplasms; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Male; Mice; Mice, Nude; Mice, SCID; Mice, Transgenic; Oncogene Proteins, Viral; Papilloma; Papillomaviridae; Papillomavirus E7 Proteins; Repressor Proteins; Sirolimus | 2010 |
Chemomodulatory effects of Aegle marmelos against DMBA-induced skin tumorigenesis in Swiss albino mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aegle; Animals; Antineoplastic Agents; Apoptosis; Cell Transformation, Neoplastic; Chemoprevention; Croton Oil; Medicine, Ayurvedic; Mice; Phytotherapy; Plant Extracts; Plant Preparations; Skin; Skin Neoplasms; Tumor Burden | 2010 |
FSP1+ fibroblasts promote skin carcinogenesis by maintaining MCP-1-mediated macrophage infiltration and chronic inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Chemokine CCL2; Chronic Disease; Fibroblasts; Humans; Inflammation; Macrophages; Mice; Mice, Inbred BALB C; Mice, Transgenic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Mice lacking MSK1 and MSK2 show reduced skin tumor development in a two-stage chemical carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Skin Neoplasms | 2011 |
TRPV1-antagonist AMG9810 promotes mouse skin tumorigenesis through EGFR/Akt signaling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acrylamides; Animals; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; ErbB Receptors; Female; Humans; Keratinocytes; Male; Mice; Mice, Hairless; Proto-Oncogene Proteins c-akt; Signal Transduction; Skin Neoplasms; TRPV Cation Channels | 2011 |
Diets high in corn oil or extra-virgin olive oil provided from weaning advance sexual maturation and differentially modify susceptibility to mammary carcinogenesis in female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Analysis of Variance; Animals; Body Weight; Breast; Caseins; Cell Transformation, Neoplastic; Corn Oil; Dietary Fats; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Kisspeptins; Mammary Neoplasms, Experimental; Molecular Sequence Data; Olive Oil; Ovary; Plant Oils; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sexual Maturation | 2011 |
Contact by melanoma cells causes malignant transformation of human epithelial-like stem cells via alpha V integrin activation of transforming growth factor β1 signaling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Cell Transformation, Neoplastic; Cells, Cultured; Coculture Techniques; Humans; Integrin alphaV; Melanoma; Mutagens; Signal Transduction; Stem Cells; Transforming Growth Factor beta1 | 2011 |
Lunasin-aspirin combination against NIH/3T3 cells transformation induced by chemical carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anacardic Acids; Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Carcinogens; Cell Line, Transformed; Cell Proliferation; Cell Transformation, Neoplastic; Methylcholanthrene; Mice; NIH 3T3 Cells; Soybean Proteins | 2011 |
Conjugates of 3α-methoxyserrat-14-en-21β-ol (PJ-1) and 3β-methoxyserrat-14-en-21β-ol (PJ-2) as cancer chemopreventive agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Carcinogenicity Tests; Cell Transformation, Neoplastic; Epstein-Barr Virus Infections; Flavanones; Genistein; Herpesvirus 4, Human; Hesperidin; Isoflavones; Mice; Oleanolic Acid; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2011 |
Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Epidermal Cells; Epidermis; Female; Gene Expression Regulation, Neoplastic; Keratinocytes; Mice; Mice, Knockout; MicroRNAs; ras Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
CXCR3 enhances a T-cell-dependent epidermal proliferative response and promotes skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Proliferation; Cell Transformation, Neoplastic; Epidermis; Humans; Lymphocytes, Tumor-Infiltrating; Methylcholanthrene; Mice; Mice, Mutant Strains; Receptors, CXCR3; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2011 |
Effect of green propolis on oral epithelial dysplasia in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Epithelial Cells; Male; Precancerous Conditions; Propolis; Rats; Rats, Wistar; Severity of Illness Index; Tongue Neoplasms | 2011 |
A ΔRaf1-ER-inducible oncogenic zebrafish liver cell model identifies hepatocellular carcinoma signatures.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms, Experimental; MAP Kinase Signaling System; Neoplasm Transplantation; Proto-Oncogene Proteins c-raf; Tamoxifen; Transplantation, Heterologous; Tumor Cells, Cultured; Zebrafish | 2011 |
Overexpression of hedgehog signaling is associated with epidermal tumor formation in vitamin D receptor-null mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcitriol; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Epidermis; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Calcitriol; Signal Transduction; Skin Neoplasms; Ultraviolet Rays | 2011 |
Resveratrol and black tea polyphenol combination synergistically suppress mouse skin tumors growth by inhibition of activated MAPKs and p53.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Activation; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Phosphorylation; Polyphenols; Proliferating Cell Nuclear Antigen; Protein Stability; Remission Induction; Resveratrol; Skin Neoplasms; Stilbenes; Tea; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2011 |
14-3-3σ and p63 play opposing roles in epidermal tumorigenesis.
Topics: 14-3-3 Proteins; 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Gene Silencing; Homeostasis; Keratinocytes; Mice; Mice, Mutant Strains; Phosphoproteins; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trans-Activators | 2011 |
Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Cell Dedifferentiation; Cell Line, Tumor; Cell Transformation, Neoplastic; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Dominant role of HPV16 E7 in anal carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anal Canal; Animals; Anus Neoplasms; Cell Transformation, Neoplastic; Female; Human papillomavirus 16; Humans; Male; Mice; Mice, Transgenic; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Repressor Proteins | 2011 |
The effect of childbirth on carcinogenesis of DMBA-induced breast cancer in female SD rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Nuclear; Carcinogens; Cell Transformation, Neoplastic; Female; Ki-67 Antigen; Mammary Neoplasms, Experimental; Minichromosome Maintenance Complex Component 2; Nuclear Proteins; Parity; Pregnancy; Proliferating Cell Nuclear Antigen; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Tumor Burden | 2011 |
A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cell Movement; Cell Transformation, Neoplastic; Cytoskeleton; Disease Progression; Endothelial Cells; Focal Adhesion Protein-Tyrosine Kinases; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Neovascularization, Pathologic; Papilloma; Phorbols; Protein Serine-Threonine Kinases; Skin Neoplasms; Vascular Endothelial Growth Factor Receptor-2 | 2012 |
Chemomodulatory potential of Glycine max against murine skin and cervical papillomagenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Catalase; Cell Transformation, Neoplastic; Chemoprevention; Female; Glutathione Transferase; Glycine max; Lactoylglutathione Lyase; Methylcholanthrene; Mice; NAD(P)H Dehydrogenase (Quinone); Neoplasms, Experimental; Papilloma; Plant Extracts; Skin Neoplasms; Superoxide Dismutase; Uterine Cervical Neoplasms | 2011 |
Carcinogen treatment in mouse selectively expressing activated N-Ras Q61K in melanocytes recapitulates metastatic cutaneous melanoma development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Substitution; Animals; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Genes, ras; Humans; Melanocytes; Melanoma; Mice; Mice, Inbred C57BL; Mutation; Neoplasm Metastasis; Neoplasm Transplantation; Skin Neoplasms | 2012 |
Ellagic acid coordinately attenuates Wnt/β-catenin and NF-κB signaling pathways to induce intrinsic apoptosis in an animal model of oral oncogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; beta Catenin; Blotting, Western; Cell Transformation, Neoplastic; Cheek; Cricetinae; Disease Models, Animal; Down-Regulation; Ellagic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Mouth Mucosa; Mouth Neoplasms; NF-kappa B; Plant Extracts; Wnt Signaling Pathway | 2013 |
Effect of Cu supplementation on genomic instability in chemically-induced mammary carcinogenesis in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Copper; Dietary Supplements; Female; Genomic Instability; Mammary Neoplasms, Experimental; Microsatellite Repeats; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2011 |
Combined effect of cyclin D3 expression and abrogation of cyclin D1 prevent mouse skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Cyclin D2; Cyclin D3; Gene Expression Regulation; Mice; Mice, Transgenic; Oncogene Protein p21(ras); Papilloma; Skin; Skin Neoplasms; Tumor Burden | 2012 |
Langerhans cells facilitate epithelial DNA damage and squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA Damage; Genes, ras; Humans; Keratinocytes; Langerhans Cells; Mice; Mice, Transgenic; Skin Neoplasms; T-Lymphocytes | 2012 |
Loss of the platelet activating factor receptor in mice augments PMA-induced inflammation and cutaneous chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2012 |
Negative feedback mechanisms surpass the effect of intrinsic EGFR activation during skin chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Cell Transformation, Neoplastic; Ear Neoplasms; ErbB Receptors; Feedback, Physiological; Female; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neoplasm Proteins; Point Mutation; Real-Time Polymerase Chain Reaction; Skin Neoplasms | 2012 |
Inhibitory effects of Zengshengping fractions on DMBA-induced buccal pouch carcinogenesis in hamsters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Cricetinae; Drugs, Chinese Herbal; Male; Mesocricetus; Mouth Neoplasms | 2012 |
Cytotoxic activities and anti-tumor-promoting effects of microbial transformation products of prenylated chalcones from Angelica keiskei.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angelica; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; Apoptosis; Aspergillus; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Chalcones; Humans; Mice; Molecular Structure; Prenylation; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2012 |
Cucurbitane triterpenoids from the leaves of Momordica charantia, and their cancer chemopreventive effects and cytotoxicities.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Glycosides; Humans; Mice; Molecular Structure; Momordica charantia; Plant Leaves; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes; Tumor Cells, Cultured | 2012 |
Androgen resistance in female mice increases susceptibility to DMBA-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androgens; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Epithelial Cells; Female; Genetic Predisposition to Disease; Gonadotropins, Pituitary; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Androgen; Testosterone | 2012 |
A keratin 15 containing stem cell population from the hair follicle contributes to squamous papilloma development in the mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Female; Genes, ras; Hair Follicle; Humans; Integrases; Keratin-15; Keratinocytes; Laser Capture Microdissection; Mice; Mice, Transgenic; Mutation; Papilloma; Skin; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate | 2013 |
Gene expression signature of DMBA-induced hamster buccal pouch carcinomas: modulation by chlorophyllin and ellagic acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Chlorophyllides; Cricetinae; Dietary Supplements; Ellagic Acid; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Transcription, Genetic; Tumor Burden | 2012 |
Deficiency of the Kruppel-like factor KLF4 correlates with increased cell proliferation and enhanced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Adhesion; Cell Differentiation; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Female; Gene Expression Regulation, Neoplastic; Humans; Keratinocytes; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mice; Mice, Transgenic; RNA Interference; RNA, Small Interfering; Skin Neoplasms; Tamoxifen; Tetradecanoylphorbol Acetate | 2012 |
Miz1 is a critical repressor of cdkn1a during skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p21; Mice; Mice, Transgenic; Neoplasms, Experimental; Nuclear Proteins; Protein Inhibitors of Activated STAT; Protein Structure, Tertiary; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ubiquitin-Protein Ligases | 2012 |
A zebrafish model to study and therapeutically manipulate hypoxia signaling in tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Hypoxia; Cell Transformation, Neoplastic; Disease Models, Animal; Hypoxia-Inducible Factor 1; Intestinal Neoplasms; Liver Neoplasms, Experimental; Signal Transduction; Tumor Suppressor Proteins; Zebrafish Proteins | 2012 |
Effects of the tropical ginger compound,1'-acetoxychavicol acetate, against tumor promotion in K5.Stat3C transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alpinia; Animals; Benzyl Alcohols; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Fluocinolone Acetonide; Humans; Mice; Mice, Transgenic; NF-kappa B; Plant Extracts; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Zingiber officinale | 2012 |
Geraniol modulates cell proliferation, apoptosis, inflammation, and angiogenesis during 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acyclic Monoterpenes; Animals; Apoptosis; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Proliferation; Cell Transformation, Neoplastic; Cricetinae; Inflammation; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Neoplasms, Experimental; Neovascularization, Pathologic; Terpenes | 2012 |
Ei24-deficiency attenuates protein kinase Cα signaling and skin carcinogenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Apoptosis Regulatory Proteins; Binding, Competitive; Cell Transformation, Neoplastic; Clone Cells; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cytoprotection; Enzyme Stability; ErbB Receptors; Female; Humans; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Molecular Sequence Data; Nuclear Proteins; Protein Binding; Proteolysis; Signal Transduction; Skin Neoplasms; Transcriptional Activation | 2012 |
Tetraspanin CD151 plays a key role in skin squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Proliferation; Cell Transformation, Neoplastic; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Integrin alpha6beta4; Mice; Mice, Knockout; Phosphorylation; Signal Transduction; Skin Neoplasms; STAT3 Transcription Factor; Tetraspanin 24; Tumor Cells, Cultured | 2013 |
PKCα suppresses 7,12-dimethylbenz[a]anthracene-induced skin tumor formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Female; Mice; Mice, Knockout; Protein Kinase C-alpha; Skin Neoplasms | 2012 |
Progression of mouse skin carcinogenesis is associated with increased ERα levels and is repressed by a dominant negative form of ERα.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Cytoskeleton; Estrogen Receptor alpha; Estrogen Receptor beta; Genes, Dominant; Mice; Neoplasm Proteins; Skin Neoplasms; Transfection | 2012 |
BAC CGH-array identified specific small-scale genomic imbalances in diploid DMBA-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Banding; Chromosomes, Artificial, Bacterial; Chromosomes, Mammalian; Comparative Genomic Hybridization; Diploidy; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred WKY | 2012 |
Energy balance modulates mouse skin tumor promotion through altered IGF-1R and EGFR crosstalk.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Caloric Restriction; Carcinogens; Cell Cycle; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Diet; Energy Metabolism; ErbB Receptors; Female; Insulin-Like Growth Factor I; Keratinocytes; Mice; Mice, Inbred ICR; Obesity; Papilloma; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Receptor, IGF Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Skin Neoplasms; TOR Serine-Threonine Kinases | 2012 |
IL-1R-MyD88 signaling in keratinocyte transformation and carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Transformation, Neoplastic; ErbB Receptors; Genes, ras; I-kappa B Proteins; Inflammation; Interleukin-1alpha; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myeloid Differentiation Factor 88; NF-kappa B; Phosphorylation; Receptors, Interleukin-1; Signal Transduction; Skin Neoplasms | 2012 |
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Animals, Inbred Strains; Azoxymethane; Cell Transformation, Neoplastic; Chemokines, CXC; Colitis; Colonic Neoplasms; Dermatitis, Contact; Dextran Sulfate; Gene Expression; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Papilloma; Peroxidase; Precancerous Conditions; Receptors, Interleukin-8B; Skin Neoplasms; Statistics, Nonparametric; Tetradecanoylphorbol Acetate; Tumor Burden | 2012 |
Chemopreventive potential of Annona muricata L leaves on chemically-induced skin papillomagenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Annona; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Croton Oil; Male; Mice; Mice, Inbred ICR; Papilloma; Phytotherapy; Plant Extracts; Plant Leaves; Skin Neoplasms | 2012 |
Interactions between wild-type and mutant Ras genes in lung and skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Epistasis, Genetic; Female; Genes, ras; Lung; Lung Neoplasms; Male; Mice; Mice, Knockout; Models, Genetic; Mutation; ras Proteins; Skin; Skin Neoplasms; Urethane | 2013 |
Topoisomerase II-mediated DNA cleavage and mutagenesis activated by nitric oxide underlie the inflammation-associated tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Cell Transformation, Neoplastic; Coculture Techniques; DNA Cleavage; DNA Topoisomerases, Type II; Etoposide; HCT116 Cells; HL-60 Cells; Humans; Inflammation; Mice; Mice, Knockout; Mutagenesis; Nitric Oxide; Nitric Oxide Donors; Pyridines; S-Nitrosoglutathione | 2013 |
Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptor Proteins, Signal Transducing; Animals; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Caspase 1; Cell Proliferation; Cell Transformation, Neoplastic; Cytokines; Cytoskeletal Proteins; Down-Regulation; Epithelium; Humans; Inflammasomes; Inflammation; Keratinocytes; Mice; Mice, Knockout; Myeloid Cells; Neoplasms, Squamous Cell; Organ Specificity; Receptors, Interleukin-1; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Microenvironment; Tumor Suppressor Protein p53 | 2012 |
The p53-p66Shc apoptotic pathway is dispensable for tumor suppression whereas the p66Shc-generated oxidative stress initiates tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Ultraviolet Rays | 2013 |
Spatiotemporal assessments of dermal hyperemia enable accurate prediction of experimental cutaneous carcinogenesis as well as chemopreventive activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Carcinogens; Celecoxib; Cell Transformation, Neoplastic; Female; Hyperemia; Inflammation; Mice; Optical Imaging; Pyrazoles; Skin; Skin Neoplasms; Sulfonamides; Ultraviolet Rays | 2013 |
Baicalein inhibits DMBA/TPA-induced skin tumorigenesis in mice by modulating proliferation, apoptosis, and inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Female; Flavanones; Hyperplasia; Inflammation; Mice; Mice, Inbred C57BL; Plant Extracts; Scutellaria baicalensis; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2013 |
Bub1 kinase activity drives error correction and mitotic checkpoint control but not tumor suppression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Aurora Kinase B; Aurora Kinases; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Segregation; Female; Fibroblasts; Gene Knock-In Techniques; Histones; M Phase Cell Cycle Checkpoints; Male; Mice; Phosphorylation; Protein Serine-Threonine Kinases; Threonine | 2012 |
Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Adhesion; Cell Cycle; Cell Differentiation; Cell Lineage; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Epidermis; Hair Follicle; Integrin alpha3; Keratin-15; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Skin Neoplasms; Staining and Labeling | 2012 |
Anti-cell proliferative efficacy of ferulic acid against 7, 12-dimethylbenz(a) anthracene induced hamster buccal pouch carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Coumaric Acids; Cricetinae; Cyclin D1; Immunoenzyme Techniques; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Neoplasms, Experimental; Proliferating Cell Nuclear Antigen; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2012 |
Chemopreventive potential of coumarin in 7, 12-dimethylbenz[a] anthracene induced hamster buccal pouch carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticoagulants; Carcinogens; Carcinoma, Squamous Cell; Cell Proliferation; Cell Transformation, Neoplastic; Coumarins; Cricetinae; Lipid Peroxidation; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Neoplasms, Experimental; Thiobarbituric Acid Reactive Substances | 2012 |
Anti-tumor initiating potential of andrographolide in 7,12-dimethylbenz[a]anthracene induced hamster buccal pouch carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Antioxidants; Carcinogens; Carcinoma, Squamous Cell; Catalase; Cell Transformation, Neoplastic; Cricetinae; Diterpenes; Lipid Peroxidation; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Neoplasms, Experimental; Superoxide Dismutase | 2012 |
Modulating effect of lupeol on the expression pattern of apoptotic markers in 7, 12-dimethylbenz(a)anthracene induced oral carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Apoptosis; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cricetinae; Enzyme-Linked Immunosorbent Assay; Immunoenzyme Techniques; Male; Mesocricetus; Mouth Neoplasms; Pentacyclic Triterpenes | 2012 |
Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently prevents skin carcinogenesis by suppressing the PKD1-dependent signaling pathway in CD34+ skin stem cells and skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetates; Animals; Antigens, CD34; Catechin; CCAAT-Enhancer-Binding Proteins; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Extracellular Signal-Regulated MAP Kinases; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitotic Index; Nitric Oxide Synthase Type II; Ornithine Decarboxylase; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2013 |
Chemopreventive effect of Ardisia crispa hexane fraction on the peri-initiation phase of mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ardisia; Carcinogens; Cell Transformation, Neoplastic; Chemoprevention; Croton Oil; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Plant Extracts; Skin Neoplasms | 2013 |
Inhibitory effects of 17beta-estradiol and 4-n-octylphenol on 7,12-dimethylbenz[a]anthracene-induced mammary tumor development in human c-Ha-ras proto-oncogene transgenic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Genetically Modified; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Estradiol; Female; Gene Transfer Techniques; Genes, ras; Genetic Predisposition to Disease; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Phenols; Proto-Oncogene Mas; Rats; Tumor Cells, Cultured | 2002 |
[Effect of taixian tablet on hamster buccal pouch carcinogenesis].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Cell Transformation, Neoplastic; Cricetinae; Drugs, Chinese Herbal; Female; Leukoplakia; Male; Mesocricetus; Mouth Neoplasms; Tablets | 1998 |
Novel murine mammary epithelial cell lines that form osteolytic bone metastases: effect of strain background on tumor homing.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Polyomavirus Transforming; Antineoplastic Agents, Hormonal; Bone Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Epithelial Cells; Female; Genes, ras; Heart Ventricles; Humans; Keratins; Liver Neoplasms, Experimental; Male; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Neoplastic Cells, Circulating; Osteolysis; Osteopontin; Retroviridae; Sialoglycoproteins; Transfection; Tumor Cells, Cultured | 2003 |
IL-1 alpha, innate immunity, and skin carcinogenesis: the effect of constitutive expression of IL-1 alpha in epidermis on chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA-Binding Proteins; Epidermis; Female; Humans; Immunity, Innate; Interleukin-1; Keratin-14; Keratins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nuclear Proteins; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2003 |
The latent membrane protein 1 of Epstein-Barr virus and loss of the INK4a locus: paradoxes resolve to cooperation in carcinogenesis in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; Disease Progression; Disease Susceptibility; DNA; DNA Primers; Epidermal Cells; Epidermis; Epithelial Cells; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Mice; Mice, Knockout; Mice, Transgenic; Nasopharyngeal Neoplasms; Papilloma; Polymerase Chain Reaction; Skin Neoplasms; Viral Matrix Proteins | 2003 |
Long term inhibition by estradiol or progesterone of melatonin secretion after administration of a mammary carcinogen, the dimethyl benz(a)anthracene, in Sprague-Dawley female rat; inhibitory effect of Melatonin on mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenergic beta-Agonists; Animals; Antioxidants; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Estradiol; Female; Isoproterenol; Mammary Neoplasms, Animal; Melatonin; Pineal Gland; Progesterone; Rats; Rats, Sprague-Dawley | 2003 |
Suprabasal alpha6beta4 integrin expression in epidermis results in enhanced tumourigenesis and disruption of TGFbeta signalling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cadherins; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; DNA-Binding Proteins; Enzyme Activation; Epidermis; Integrin alpha6beta4; Keratinocytes; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; Neoplasms, Experimental; Phosphatidylinositol 3-Kinases; Signal Transduction; Smad2 Protein; Smad3 Protein; Trans-Activators; Transforming Growth Factor beta | 2003 |
Compounds obtained from sida acuta with the potential to induce quinone reductase and to inhibit 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesions in a mouse mammary organ culture model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animal Use Alternatives; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Enzyme Induction; Malvaceae; Mammary Glands, Animal; Mice; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Organ Culture Techniques; Plant Extracts; Structure-Activity Relationship; Tumor Cells, Cultured | 2003 |
[Cutaneous oncogenesis in Cricetus auratus (hamster) by 9,10-dimethyl-1,2-benzanthracene].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Benz(a)Anthracenes; Carcinogenesis; Cell Transformation, Neoplastic; Cricetinae; Humans | 1957 |
Effect of ionizing radiation on 9,10-dimethyl-1,2-benzanthracene tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogenesis; Cell Transformation, Neoplastic; Neoplasms, Experimental; Radiation Effects; Radiation, Ionizing | 1962 |
Topical application of the immunosuppressant tacrolimus accelerates carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Carcinogens; Carcinoma, Squamous Cell; CD4 Lymphocyte Count; Cell Transformation, Neoplastic; Female; Immunosuppressive Agents; Lymph Nodes; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tacrolimus | 2003 |
Suppression of 7,12-dimethylbenz[alpha]anthracene-induced carcinogenesis and hypercholesterolaemia in rats by tocotrienol-rich fraction isolated from rice bran oil.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acyl Coenzyme A; Administration, Oral; Alkaline Phosphatase; Animals; Antioxidants; Carcinogens; Cell Transformation, Neoplastic; Cholesterol; Female; Glutathione Transferase; Hypercholesterolemia; Liver; Mammary Neoplasms, Animal; Plant Oils; Rats; Rats, Sprague-Dawley; Rice Bran Oil; Tocotrienols | 2003 |
Inhibition of AP-1 and neoplastic transformation by fresh apple peel extract.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Electron Spin Resonance Spectroscopy; Genes, Reporter; Hydrogen Peroxide; Hydroxyl Radical; Luciferases; Malus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Phosphorylation; Plant Extracts; Reactive Oxygen Species; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcriptional Activation; Transgenes; Ultraviolet Rays | 2004 |
DDB2 gene disruption leads to skin tumors and resistance to apoptosis after exposure to ultraviolet light but not a chemical carcinogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Caspase 3; Caspases; Cell Survival; Cell Transformation, Neoplastic; DNA-Binding Proteins; Fibroblasts; Gene Deletion; Mice; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays | 2004 |
Terminal endbuds and acini as the respective major targets for chemical and sporadic carcinogenesis in the mammary glands of human c-Ha-ras protooncogene transgenic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Genetically Modified; Carcinogens; Cell Division; Cell Transformation, Neoplastic; DNA Primers; Female; Genes, ras; Humans; In Situ Hybridization, Fluorescence; Mammary Neoplasms, Experimental; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Rats; Reverse Transcriptase Polymerase Chain Reaction | 2004 |
Lack of significant effects of genistein on the progression of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in ovariectomized Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Disease Progression; Dose-Response Relationship, Drug; Estrogens; Female; Genistein; Incidence; Mammary Neoplasms, Experimental; Ovariectomy; Random Allocation; Rats; Rats, Sprague-Dawley | 2003 |
Novel p21-activated kinase-dependent protrusions characteristically formed at the edge of transformed cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animals; Calcium-Binding Proteins; Carcinogens; cdc42 GTP-Binding Protein; Cell Cycle Proteins; Cell Line, Transformed; Cell Line, Tumor; Cell Size; Cell Surface Extensions; Cell Transformation, Neoplastic; Enzyme Activation; Epithelial Cells; Guanine Nucleotide Exchange Factors; Lysophospholipids; Microscopy, Electron, Scanning; Models, Biological; p21-Activated Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Inbred F344; Rho Guanine Nucleotide Exchange Factors; Tetradecanoylphorbol Acetate; Time Factors; Trachea | 2004 |
Strain-dependent differences in malignant conversion of mouse skin tumors is an inherent property of the epidermal keratinocyte.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Disease Progression; Epidermis; Genetic Predisposition to Disease; Humans; Infant, Newborn; Keratinocytes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred SENCAR; Mice, Nude; Oncogene Proteins, Viral; Papilloma; Papillomaviridae; Papillomavirus E7 Proteins; Repressor Proteins; Skin Neoplasms; Species Specificity | 2004 |
Lack of modifying effects of an estrogenic compound atrazine on 7,12-dimethylbenz(a)anthracene-induced ovarian carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Administration, Oral; Animals; Atrazine; Carcinogens; Cell Transformation, Neoplastic; Drug Interactions; Endocrine System; Female; Herbicides; Neoplasms, Experimental; Ovarian Neoplasms; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Receptors, Estrogen | 2004 |
Overexpression of the colony-stimulating factor (CSF-1) and/or its receptor c-fms in mammary glands of transgenic mice results in hyperplasia and tumor formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Cycle; Cell Transformation, Neoplastic; Female; Humans; Hyperplasia; Macrophage Colony-Stimulating Factor; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Receptor, Macrophage Colony-Stimulating Factor | 2004 |
Early detection of alterations associated to oral cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Hyperplasia; Mesocricetus; Mouth Neoplasms; Neoplasms, Radiation-Induced; Nucleolus Organizer Region; Silver Staining; Statistics, Nonparametric; Tetradecanoylphorbol Acetate | 2000 |
Alpha 2-HS glycoprotein (fetuin-A) modulates murine skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; alpha-2-HS-Glycoprotein; Animals; Apoptosis; Blood Proteins; Cell Proliferation; Cell Transformation, Neoplastic; Mice; Mice, Inbred C57BL; Mutation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Embryo, Mammalian; Female; Fibroblasts; Gene Dosage; Genes, Tumor Suppressor; Heterozygote; Homozygote; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental | 2004 |
Crucial role of phospholipase Cepsilon in chemical carcinogen-induced skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Mice; Mice, Inbred C57BL; Mutation; Phosphoinositide Phospholipase C; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2004 |
Ploidy analysis of field cancerization and cancer development in the hamster cheek pouch carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma; Carcinoma in Situ; Cell Proliferation; Cell Transformation, Neoplastic; Cricetinae; Disease Models, Animal; DNA, Neoplasm; Epithelium; Female; Hyperplasia; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Ploidies; Precancerous Conditions | 2005 |
Overexpression of 5-lipoxygenase and cyclooxygenase 2 in hamster and human oral cancer and chemopreventive effects of zileuton and celecoxib.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Carcinogens; Carcinoma, Squamous Cell; Celecoxib; Cell Transformation, Neoplastic; Chemoprevention; Cricetinae; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Humans; Hydroxyurea; Immunohistochemistry; In Situ Hybridization; Lipoxygenase Inhibitors; Male; Membrane Proteins; Mesocricetus; Mouth Neoplasms; Neoplasms, Experimental; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Up-Regulation | 2005 |
The effect of PPARgamma ligands on UV- or chemically-induced carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Chromans; Diet; Female; Keratinocytes; Ligands; Mice; PPAR gamma; RNA, Messenger; Rosiglitazone; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thiazolidinediones; Troglitazone; Ultraviolet Rays | 2005 |
Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Growth Processes; Cell Transformation, Neoplastic; Chromosome Mapping; DNA Damage; DNA-Binding Proteins; Early Growth Response Protein 1; Female; Fibroblasts; Gene Expression Profiling; Genes, Tumor Suppressor; Immediate-Early Proteins; Male; Mice; Mice, Inbred C57BL; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Suppressor Protein p53; Up-Regulation | 2005 |
Preventive and curative effect of melatonin on mammary carcinogenesis induced by dimethylbenz[a]anthracene in the female Sprague-Dawley rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antioxidants; Carcinogens; Cell Transformation, Neoplastic; DNA Damage; Environmental Exposure; Female; Humans; Mammary Neoplasms, Animal; Melatonin; Rats; Rats, Sprague-Dawley; Risk Factors | 2005 |
Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Carcinogens; Caspase 3; Caspases; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; DNA, Antisense; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Papilloma; Phosphoproteins; Sarcoma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 2005 |
Reduced excision repair cross-complementing 1 expression associates with enhanced papilloma formation and fibroblast transformation after genetic disruption of secreted protein acidic and rich in cysteine.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; DNA Adducts; DNA-Binding Proteins; Embryo, Mammalian; Endonucleases; Female; Fibroblasts; Gene Expression; Genotype; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Osteonectin; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Epidermis; Humans; Lymph Nodes; Membrane Glycoproteins; Mice; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Protein Kinase C; Proteinase Inhibitory Proteins, Secretory; ras Proteins; Serine Endopeptidases; Serine Proteinase Inhibitors | 2005 |
Potentiation of tumor formation by topical administration of 15-deoxy-delta12,14-prostaglandin J2 in a model of skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Cyclooxygenase 2; Disease Progression; Drug Interactions; Female; Immunologic Factors; Keratinocytes; Mice; Papilloma; Prostaglandin D2; Skin Neoplasms | 2006 |
Inhibitory effect of inducible nitric oxide synthase inhibitors on DMBA-induced hamster buccal-pouch squamous-cell carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cricetinae; Enzyme Inhibitors; Guanidines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II | 2005 |
Effect of genistein on DMBA-induced oral carcinogenesis in hamster.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Cricetinae; Genistein; Male; Mesocricetus; Mouth Neoplasms; Neoplasms, Experimental; Neovascularization, Pathologic | 2006 |
The role of human prolactin and its antagonist, G129R, in mammary gland development and DMBA-initiated tumorigenesis in transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Female; Mammary Glands, Animal; Mammary Neoplasms, Animal; Metallothionein; Mice; Mice, Transgenic; Prolactin; Promoter Regions, Genetic | 2005 |
Lack of expression of the EP2 but not EP3 receptor for prostaglandin E2 results in suppression of skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Growth Processes; Cell Transformation, Neoplastic; Cyclic AMP; Dinoprostone; Drug Eruptions; Female; Hyperplasia; Keratinocytes; Mice; Mice, Knockout; Neovascularization, Pathologic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2005 |
Autofluorescence characterization for the early diagnosis of neoplastic changes in DMBA/TPA-induced mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biopsy, Needle; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Disease Models, Animal; Early Diagnosis; Female; Immunohistochemistry; Linear Models; Mice; Multivariate Analysis; Probability; Sensitivity and Specificity; Skin Neoplasms; Spectrometry, Fluorescence | 2005 |
Enhancement by acrylamide of N-methyl-N-nitrosourea-induced rat mammary tumor development-possible application for a model to detect co-modifiers of carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acrylamide; Administration, Oral; Alkylating Agents; Animals; Carcinogens; Cell Transformation, Neoplastic; Disease Models, Animal; Drug Interactions; Female; Mammary Neoplasms, Animal; Methylnitrosourea; Nitrosamines; Rats; Rats, Sprague-Dawley; Thyroid Neoplasms | 2005 |
Unexpected roles for pRb in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; E2F Transcription Factors; Mice; Papilloma; Phosphorylation; Retinoblastoma Protein; Signal Transduction; Skin Neoplasms; Tumor Suppressor Protein p53 | 2005 |
The preventive effect of salvianolic acid B on malignant transformation of DMBA-induced oral premalignant lesion in hamsters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Benzofurans; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Chemoprevention; Cricetinae; Male; Mesocricetus; Mouth Neoplasms; Neovascularization, Pathologic; Precancerous Conditions; Random Allocation | 2006 |
7,12-dimethylbenz(a)anthracene treatment of a c-rel mouse mammary tumor cell line induces epithelial to mesenchymal transition via activation of nuclear factor-kappaB.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cadherins; Carcinoma, Adenosquamous; Cell Adhesion; Cell Growth Processes; Cell Line, Tumor; Cell Transformation, Neoplastic; Epithelial Cells; Genes, rel; I-kappa B Proteins; Mammary Neoplasms, Experimental; Mesoderm; Mice; Mice, Transgenic; NF-kappa B; NF-KappaB Inhibitor alpha; Proto-Oncogene Proteins c-rel | 2006 |
Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Proliferation; Cell Transformation, Neoplastic; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Minichromosome Maintenance Complex Component 7; Mutation; Neoplasm Proteins; Neoplasms, Experimental; Nuclear Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Association of gene expression with sequential proliferation, differentiation and tumor formation in murine skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers; Carcinogens; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Female; Filaggrin Proteins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Oligonucleotide Array Sequence Analysis; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Ras mutation promotes p53 activation and apoptosis of skin keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Enzyme Inhibitors; Genes, ras; Keratinocytes; Mice; Mice, Inbred C57BL; Mitochondria; Mutation; NADPH Oxidases; Onium Compounds; Protein Transport; rac1 GTP-Binding Protein; Reactive Oxygen Species; RNA, Small Interfering; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2006 |
Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Growth Processes; Cell Transformation, Neoplastic; Enzyme Activation; Ephrin-A1; Female; Genetic Predisposition to Disease; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Receptor, EphA2; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Epidermis; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Proto-Oncogene Proteins c-myc; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2006 |
Early phenotypic and genotypic alterations in submandibular gland oncogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Substitution; Analysis of Variance; Animals; Asparagine; Cell Transformation, Neoplastic; DNA Mutational Analysis; Immunoenzyme Techniques; Male; Mutation, Missense; Point Mutation; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Submandibular Gland Neoplasms; Threonine; Tumor Suppressor Protein p53 | 2006 |
Therapeutic effect of boron neutron capture therapy (BNCT) on field cancerized tissue: inhibition of DNA synthesis and lag in the development of second primary tumors in precancerous tissue around treated tumors in DMBA-induced carcinogenesis in the hamst
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Boron Neutron Capture Therapy; Carcinogens; Cell Transformation, Neoplastic; Cricetinae; Disease Models, Animal; DNA, Neoplasm; Mesocricetus; Mouth Neoplasms; Neoplasms, Multiple Primary; Precancerous Conditions; Radiotherapy Dosage | 2007 |
Inhibitory effects of asiatic acid on 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Induction; Female; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type II; Papilloma; Pentacyclic Triterpenes; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Triterpenes | 2007 |
Bin1 ablation in mammary gland delays tissue remodeling and drives cancer progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptor Proteins, Signal Transducing; Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Disease Progression; Female; Gene Deletion; Genes, ras; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Molecular Sequence Data; Nerve Tissue Proteins; Pregnancy; Tumor Suppressor Proteins | 2007 |
Pro/antioxidant status and AP-1 transcription factor in murine skin following topical exposure to cumene hydroperoxide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzene Derivatives; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Female; Gene Expression Regulation, Neoplastic; Glutathione; Mice; Mice, Transgenic; Oxidation-Reduction; Oxidative Stress; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2007 |
Activation of Notch signaling in tumorigenesis of experimental pancreatic cancer induced by dimethylbenzanthracene in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Homeodomain Proteins; Humans; Male; Mice; Mice, Inbred C57BL; Mutation; Pancreatic Neoplasms; ras Proteins; Receptors, Notch; RNA, Messenger; Signal Transduction; Trans-Activators | 2007 |
Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Epidermis; Gene Expression Regulation, Neoplastic; Keratinocytes; Mice; Mice, Transgenic; Nevus, Pigmented; Papilloma; PPAR gamma; Retinoid X Receptor alpha; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Heavy water labeling method for measuring the effect of genistein on mammary gland carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Water; Carcinogens; Cell Transformation, Neoplastic; Deuterium Oxide; Diet; Epithelial Cells; Female; Genistein; Humans; Male; Mammary Glands, Human; Pregnancy; Rats; Rats, Sprague-Dawley | 2007 |
Dual role of inactivating Lef1 mutations in epidermis: tumor promotion and specification of tumor type.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma, Sebaceous; Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p21; Epidermis; Female; Genes, ras; Lymphoid Enhancer-Binding Factor 1; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Mutation; Sebaceous Gland Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2007 |
Ineffectiveness of American ginseng in the prevention of dimethylbenzanthracene-induced mammary tumors in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred SENCAR; Panax; Phytotherapy; Plant Preparations; Plant Roots; Selective Estrogen Receptor Modulators; Tamoxifen; Time Factors | 2006 |
Expression profile of skin papillomas with high cancer risk displays a unique genetic signature that clusters with squamous cell carcinomas and predicts risk for malignant conversion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Female; Gene Expression Profiling; Immunity, Cellular; Immunophenotyping; Mice; Mice, Inbred SENCAR; Oligonucleotide Array Sequence Analysis; Papilloma; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Lack of a significant effect of arctiin on development of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in ovariectomized Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Disease Progression; Dose-Response Relationship, Drug; Female; Furans; Glucosides; Incidence; Mammary Neoplasms, Experimental; Ovariectomy; Random Allocation; Rats; Rats, Sprague-Dawley | 2007 |
The effect of cyclooxygenase-2 overexpression on skin carcinogenesis is context dependent.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Blotting, Northern; Blotting, Western; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Dermatologic Agents; Drug Resistance, Neoplasm; Female; Humans; Interleukin-1alpha; Mice; Mice, Transgenic; Ornithine Decarboxylase; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
MAD2DeltaC induces aneuploidy and promotes anchorage-independent growth in human prostate epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Calcium-Binding Proteins; Carcinogens; Cell Cycle Proteins; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Epithelial Cells; Humans; Mad2 Proteins; Male; Mitosis; Prostate; Prostatic Neoplasms; Repressor Proteins; Sequence Deletion; Tumor Suppressor Protein p53 | 2008 |
Decreased c-kit function inhibits enhanced skin carcinogenesis in c-Ha-ras protooncogene transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Female; Genes, ras; Humans; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Transgenic; Papilloma; Polymerase Chain Reaction; Promoter Regions, Genetic; Proto-Oncogene Proteins c-kit; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2007 |
Expression of the human Cathepsin L inhibitor hurpin in mice: skin alterations and increased carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cathepsin L; Cathepsins; Cell Transformation, Neoplastic; Cysteine Endopeptidases; Humans; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Microarray Analysis; Serpins; Skin; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2007 |
Forced expression of a constitutively active form of Stat3 in mouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Epidermis; Keratinocytes; Mice; Mice, Transgenic; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate | 2008 |
Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; DNA-Binding Proteins; Fibroblasts; Gene Expression Regulation, Neoplastic; Genotype; Glucose; Heat Shock Transcription Factors; Humans; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mice, Knockout; Mutation; Phenotype; Protein Biosynthesis; Proto-Oncogene Proteins c-sis; ras Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors; Transduction, Genetic; Tumor Suppressor Protein p53 | 2007 |
Decreased 7,12-dimethylbenz[a]anthracene-induced carcinogenesis coincides with the induction of antitumor immunities in adult female B6C3F1 mice pretreated with genistein.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Cytotoxicity, Immunologic; Female; Genistein; Killer Cells, Natural; Lymphocyte Activation; Mice; STAT1 Transcription Factor; STAT4 Transcription Factor; T-Lymphocyte Subsets; T-Lymphocytes; T-Lymphocytes, Cytotoxic | 2007 |
Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch by topical application of a dual inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 tyrosine kinases.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonate 5-Lipoxygenase; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Dinoprostone; ErbB Receptors; Humans; Male; Mouth Mucosa; Mouth Neoplasms; Quinazolines; Receptor, ErbB-2 | 2008 |
Hmga1 null mice are less susceptible to chemically induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Genetic Predisposition to Disease; HMGA Proteins; Keratinocytes; Mice; Mice, Knockout; Papilloma; Proto-Oncogene Proteins c-fos; rab GTP-Binding Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
LKB1 deficiency sensitizes mice to carcinogen-induced tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; AMP-Activated Protein Kinases; Animals; Carcinogens; Cell Transformation, Neoplastic; Epidermis; Lung Neoplasms; Mice; Mice, Mutant Strains; Neoplasms, Squamous Cell; Protein Serine-Threonine Kinases; Retinoblastoma Protein; Signal Transduction; Skin Neoplasms; Tumor Suppressor Protein p53 | 2008 |
Polymeric black tea polyphenols inhibit mouse skin chemical carcinogenesis by decreasing cell proliferation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Epidermis; Female; Flavonoids; Inflammation Mediators; MAP Kinase Signaling System; Mice; Ornithine Decarboxylase; Phenols; Polymers; Polyphenols; Precancerous Conditions; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Suppressor Protein p53 | 2008 |
Chemopreventive activity of lantadenes on two-stage carcinogenesis model in Swiss albino mice: AP-1 (c-jun), NFkappaB (p65) and P53 expression by ELISA and immunohistochemical localization.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Cytoprotection; Enzyme-Linked Immunosorbent Assay; Esters; Female; Immunohistochemistry; Mice; NF-kappa B; Oleanolic Acid; Papilloma; Skin Neoplasms; Tissue Distribution; Transcription Factor AP-1; Tumor Suppressor Protein p53 | 2008 |
Stage-specific disruption of Stat3 demonstrates a direct requirement during both the initiation and promotion stages of mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Immunohistochemistry; Mice; Mice, Transgenic; Polymerase Chain Reaction; Signal Transduction; Skin Neoplasms; STAT3 Transcription Factor; Tamoxifen; Tetradecanoylphorbol Acetate | 2008 |
Histopathologic studies of DMBA-induced mouse submandibular-gland tumors with or without cryoprobe treatment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma, Pleomorphic; Animals; Benz(a)Anthracenes; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cryosurgery; Male; Mice; Neoplasms, Experimental; Precancerous Conditions; Salivary Gland Neoplasms; Submandibular Gland; Submandibular Gland Neoplasms; Time Factors | 1984 |
Effect of an anticancer agent, vinblastine, on mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Female; Herpesvirus 4, Human; Hyperplasia; Mice; Skin; Tetradecanoylphorbol Acetate; Vinblastine; Virus Activation | 1984 |
Selenium inhibition of the neoplastic transformation in preneoplastic mammary cell populations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Diet; Female; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Precancerous Conditions; Selenium; Time Factors | 1984 |
Involvement of protease in L-glutamine control of nucleic acid and polyphosphate metabolism in cells transformed by 9,10-dimethyl-1,2-benzanthracene, SV40 and H-ras oncogene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Cell Line; Cell Transformation, Neoplastic; DNA Replication; Glutamine; Humans; Kinetics; Lung; Oncogenes; Peptide Hydrolases; Polyphosphates; Protease Inhibitors; Simian virus 40; Temperature; Transcription, Genetic | 1984 |
Variation of gamma glutamyl transpeptidase activity and lectin binding in the course of carcinogenesis of the respiratory tract epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Cell Transformation, Neoplastic; Concanavalin A; Epithelium; Female; gamma-Glutamyltransferase; Lectins; Rats; Rats, Inbred F344; Respiratory Tract Neoplasms | 1983 |
Changes occurring in plasma membranes and intercellular junctions during the process of carcinogenesis and in squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Membrane; Cell Transformation, Neoplastic; Freeze Fracturing; Intercellular Junctions; Microscopy, Electron; Mouth Mucosa; Mouth Neoplasms; Rats; Rats, Inbred Strains | 1984 |
Modulation of carcinogen-induced transformation by actinomycin D in the C3H/10T 1/2 cell line.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Cell Cycle; Cell Division; Cell Line; Cell Transformation, Neoplastic; Dactinomycin; Enzyme Induction; Methylcholanthrene; Mice; Mice, Inbred C3H; RNA | 1980 |
Localization of a Mr 52,000 keratin in basal epithelial cells of the mouse bladder and expression throughout neoplastic progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Epithelium; Fluorescent Antibody Technique; Humans; Immune Sera; Keratins; Mice; Microscopy, Phase-Contrast; Molecular Weight; Rats; Urinary Bladder; Urinary Bladder Neoplasms | 1982 |
Immunity to carcinogen-induced transplantable fibrosarcoma in B2/B2 chickens. V. Relationship to tumor cell-specific delayed hypersensitivity and serum antibody.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Antibodies, Neoplasm; Antigens, Neoplasm; Cell Transformation, Neoplastic; Chickens; Epitopes; Fibrosarcoma; Fluorescent Antibody Technique; Graft Rejection; Hypersensitivity, Delayed; Immunity, Cellular; Immunization, Passive; Neoplasm Transplantation; Spleen | 1982 |
Natural host defence during oncogenesis. NK activity and dimethylbenzanthracene carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Cytotoxicity, Immunologic; Female; Interferon Inducers; Interferons; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Spleen | 1983 |
Properties of carcinogen altered mouse epidermal cells resistant to calcium-induced terminal differentiation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Calcium; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Drug Resistance; Keratins; Methylnitronitrosoguanidine; Mice; Microscopy, Electron, Scanning; Skin; Skin Neoplasms; Skin Physiological Phenomena | 1983 |
Influence of hormones on N-(4-hydroxyphenyl) retinamide inhibition of 7,12-dimethylbenz[alpha]anthracene transformation of mammary cells in organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Cell Transformation, Neoplastic; Estrogens; Female; Fenretinide; Hormones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Progesterone; Tretinoin | 1982 |
Chromosome abnormalities associated with salivary gland epithelial cell lines transformed in vitro and in vivo with evidence of a role for genetic imbalance in transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Epithelium; Karyotyping; Male; Mice; Neoplasms, Experimental; Phenotype; Salivary Glands | 1981 |
Inhibition of benzo(a)pyrene-induced transformation of C3H/10T1/2 cells by allylisopropylacetamide and isopropylvaleramide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetamides; Allylisopropylacetamide; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Cell Transformation, Neoplastic; Cells, Cultured; Mice; Time Factors | 1981 |
The structural relationships between 54,000-molecular-weight cellular tumor antigens detected in viral- and nonviral-transformed cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Mice; Molecular Weight; Peptides; Phosphopeptides; Simian virus 40; Teratoma | 1981 |
Evidence of separate pathways for viral and chemical carcinogenesis in C3H/StWi mouse mammary glands.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Antigens, Viral; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice | 1980 |
Activation of related transforming genes in mouse and human mammary carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; DNA Restriction Enzymes; DNA, Neoplasm; DNA, Viral; Female; Gene Expression Regulation; Humans; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice | 1981 |
Characterization of clones of tumorigenic feline cells transformed by a chemical carcinogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Cats; Cell Transformation, Neoplastic; Clone Cells; Mice; Mice, Nude; Neoplasm Transplantation; Sarcoma Viruses, Feline; Sarcoma, Experimental; Transplantation, Heterologous | 1981 |
Cytochemical markers of bladder carcinogenesis.
Topics: 5'-Nucleotidase; 9,10-Dimethyl-1,2-benzanthracene; Alkaline Phosphatase; Animals; Cell Membrane; Cell Transformation, Neoplastic; Female; Methylnitrosourea; Mice; Mice, Inbred C57BL; Microscopy, Electron; Neoplasms, Experimental; Nucleotidases; Organ Culture Techniques; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1981 |
Chemical carcinogen-mouse mammary tumor virus interactions in cell transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Calcium; Cell Division; Cell Transformation, Neoplastic; Cell Transformation, Viral; Clone Cells; Cytochalasin B; Epithelium; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Nude; Phenotype | 1983 |
In vitro induction of malignant transformation and in vivo resistance to tumor growth in the X/Gf mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Agar; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Embryo, Mammalian; Female; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Sarcoma, Experimental | 1983 |
Susceptibility of the mammary gland to carcinogenesis. III. The cell of origin of rat mammary carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinoma, Intraductal, Noninfiltrating; Cell Differentiation; Cell Transformation, Neoplastic; Disease Susceptibility; DNA; Epithelium; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1983 |
Highly persistent polycyclic aromatic hydrocarbon-DNA adducts in mouse skin: detection by 32P-postlabeling analysis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; DNA; DNA Repair; DNA, Neoplasm; Female; Isotope Labeling; Methylcholanthrene; Mice; Mice, Inbred BALB C; Phosphorus Radioisotopes; Polycyclic Compounds; Skin | 1983 |
Carcinogen-induced phenotypic alterations in mammary epithelial cells accompanying the development of neoplastic transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Epithelium; Female; Mammary Glands, Animal; Phenotype; Rats; Rats, Inbred Strains; Tamoxifen; Tetradecanoylphorbol Acetate | 1983 |
On the persistence of tumor initiation in two-stage carcinogenesis on mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Cell Transformation, Neoplastic; Male; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
The effect of DMBA on hamster cheek pouch mucosa in vitro: constant exposure.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Cricetinae; Mesocricetus; Mouth Mucosa; Organ Culture Techniques; Time Factors | 1983 |
Anatomical and functional vascular changes in hamster cheek pouch during carcinogenesis induced by 7, 12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Capillaries; Cell Transformation, Neoplastic; Cheek; Cricetinae; Hemodynamics; Male; Mesocricetus; Microscopy, Electron; Microscopy, Electron, Scanning; Neoplasms, Experimental | 1983 |
Inhibition of rat mammary tumor growth by purified protein A--a potential anti-tumor agent.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antigen-Antibody Complex; Cell Transformation, Neoplastic; Female; Injections, Intravenous; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Staphylococcal Protein A | 1983 |
Characterization of human transforming genes from chemically transformed, teratocarcinoma, and pancreatic carcinoma cell lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Fibrosarcoma; Humans; Kidney Neoplasms; Leiomyosarcoma; Methylnitronitrosoguanidine; Mice; Mice, Nude; Neoplasm Transplantation; Oncogenes; Pancreatic Neoplasms; Teratoma; Transfection; Transplantation, Heterologous | 1984 |
Effect of varying photoperiods on mammary morphology, DNA synthesis, and hormone profile in female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromocriptine; Cell Transformation, Neoplastic; Darkness; DNA; Estradiol; Female; Light; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Melatonin; Neoplasms, Radiation-Induced; Pregnancy; Prolactin; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Effect of estrogens on DMBA induced breast tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Castration; Cell Transformation, Neoplastic; Estradiol; Estriol; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Beta-carotene inhibition of 7,12-dimethylbenz[a]anthracene-induced transformation of murine mammary cells in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Carotenoids; Cell Transformation, Neoplastic; Epithelium; Female; In Vitro Techniques; Mammary Glands, Animal; Mice; Mice, Inbred BALB C | 1984 |
Intraclonal conversion from papilloma to carcinoma in the skin of Pgk-1a/Pgk-1b mice treated by a complete carcinogenesis process or by an initiation-promotion regimen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Female; Male; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Species Specificity | 1984 |
Suppression of the first stage of phorbol 12-tetradecanoate 13-acetate-effected tumor promotion in mouse skin by nontoxic inhibition of DNA synthesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; DNA Replication; Female; Hydroxyurea; Mice; Mice, Inbred Strains; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1984 |
Smooth-surfaced control and transformed C3H/10T-1/2 cells differ in cytology: a study by secondary electron, backscattered electron and image analysis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Fibroblasts; Mice; Mice, Inbred C3H; Microscopy, Electron; Microscopy, Electron, Scanning; Microvilli; Pregnancy | 1984 |
[Effect of ionizing radiation on the sensitivity to hormonal inducers of differentiation in induced mammary cancer in rats].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Diethylstilbestrol; Drug Resistance; Electric Stimulation; Estradiol Congeners; Female; Gamma Rays; Mammary Neoplasms, Experimental; Rats; Time Factors | 1984 |
Studies on the action of tumour promoters and antipromoters on respiratory-tract epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Epithelium; Humans; Methylnitronitrosoguanidine; Mice; Rats; Respiratory Tract Neoplasms; Tetradecanoylphorbol Acetate; Trachea; Tracheal Neoplasms | 1984 |
Stages of tumour promotion in skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Aging; Animals; Animals, Newborn; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Hyperplasia; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Wounds and Injuries | 1984 |
Protein kinase in immunoprecipitate of DMBA-transformed epithelial cells with serum from tumour-bearing rabbits.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Cell Transformation, Neoplastic; Extracellular Space; Mice; Molecular Weight; Neoplasm Proteins; Neoplasms, Experimental; Phosphoproteins; Phosphorylation; Protein Kinases; Rabbits; Urinary Bladder Neoplasms | 1980 |
[Adenylate cyclase activity in capillary walls and in hairy cells during experimental carcinogenesis].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenylyl Cyclases; Animals; Brain; Capillaries; Cell Transformation, Neoplastic; Endothelium; Histocytochemistry; Microscopy, Electron; Rats | 1980 |
Retinoid prevents transformation of cultured mammary glands by procarcinogens but not by many activated carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biotransformation; Carcinogens; Cell Transformation, Neoplastic; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Organ Culture Techniques; Retinoids; Vitamin A | 1980 |
A quantitative scanning electron microscopic study of microvilli in interphase and mitosis of carcinogen-transformed fibroblasts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Membrane; Cell Transformation, Neoplastic; Fibroblasts; Interphase; Mice; Microscopy, Electron, Scanning; Microvilli; Mitosis | 1980 |
Changes in surface morphology associated with ageing and carcinogen treatment of Chinese hamster lung cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Carcinogens; Cell Membrane; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Cricetulus; Lung; Methylnitronitrosoguanidine; Microscopy, Electron, Scanning; Time Factors | 1980 |
Studies of neoplastic development in respiratory tract epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Carcinoma in Situ; Carcinoma, Bronchogenic; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Epithelium; Lung; Lung Neoplasms; Neoplasms, Experimental; Rats; Trachea; Tracheal Neoplasms | 1981 |
Properties of cell lots suitable for focus assay in the chemical transformation of Syrian hamster cells in culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Drug Evaluation, Preclinical; Mesocricetus; Tetradecanoylphorbol Acetate | 1980 |
Sequential expression of preneoplastic and neoplastic characteristics of mouse mammary epithelial cells transformed in organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Hyperplasia; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Organ Culture Techniques; Precancerous Conditions; Transplantation, Homologous | 1981 |
[Isoelectric focusing of normal and tumor cells].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Benz(a)Anthracenes; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Hydrogen-Ion Concentration; Isoelectric Focusing; Neoplasms, Experimental; Rats | 1981 |
Organ culture passage enhances the oncogenicity of carcinogen-induced hyperplastic mammary nodules.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast; Breast Neoplasms; Cell Transformation, Neoplastic; Culture Media; Female; Hyperplasia; Organ Culture Techniques; Rats; Transplantation, Homologous | 1981 |
Immunologic reaction to oral cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigen-Antibody Reactions; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cricetinae; Humans; Lymphocytes; Mouth Neoplasms; Neoplasms, Experimental | 1981 |
Characteristics of benzo[a]pyrene and A-ring reduced 7,12-dimethyl benz[a]anthracene induced neoplastic transformation of human cells in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benz(a)Anthracenes; Benzopyrenes; Biotransformation; Cell Transformation, Neoplastic; Cells, Cultured; Humans | 1981 |
Variations in the nuclear-cytoplasmic ration during epithelial differentiation in experimental oral carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Cell Transformation, Neoplastic; Cricetinae; Cytoplasm; Epithelium; Mouth Neoplasms; Neoplasms, Experimental; Precancerous Conditions | 1981 |
Surface topography and other characteristics of non-transformed and carcinogen transformed C3H/10T 1/2 cells in mitosis, as revealed by quantitative scanning electron microscopy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anaphase; Animals; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Metaphase; Mice; Microscopy, Electron, Scanning; Microvilli; Mitosis; Prophase; Telophase | 1981 |
Uptake of hematoporphyrin derivative and sensitized photoinactivation of C3H cells with different oncogenic potential.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Cell Membrane; Cell Survival; Cell Transformation, Neoplastic; Flow Cytometry; Hematoporphyrins; Light; Mice; Mice, Inbred C3H; Microvilli; Photochemotherapy | 1981 |
Growth and differentiation of hyperplastic outgrowths derived from mouse mammary epithelial cells transformed in organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aldosterone; Animals; Cell Division; Cell Transformation, Neoplastic; Epithelium; Hydrocortisone; Hyperplasia; Insulin; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Models, Biological; Organ Culture Techniques; Prolactin | 1982 |
[An experimental study of intraoral carcinogenesis, especially the changes in the plasma membrane and intercellular junctions in cancer formation and in squamous cell carcinoma].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Membrane; Cell Transformation, Neoplastic; Intercellular Junctions; Lip Neoplasms; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1982 |
Localization of specific lesions in dimethylbenz(a)anthracene-preexposed tracheal explants.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Male; Organ Culture Techniques; Rabbits; Time Factors; Tracheal Neoplasms | 1982 |
Expression of tenascin in hamster buccal pouch mucosa during experimental carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma in Situ; Cell Transformation, Neoplastic; Cheek; Cricetinae; Disease Models, Animal; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Proteins; Precancerous Conditions; Tenascin | 1995 |
Effects of curcumin, demethoxycurcumin, bisdemethoxycurcumin and tetrahydrocurcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Line; Cell Transformation, Neoplastic; Coumaric Acids; Curcumin; Diarylheptanoids; Dose-Response Relationship, Drug; Enzyme Induction; Female; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Genetic alterations cooperate with v-Ha-ras to accelerate multistage carcinogenesis in TG.AC transgenic mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Composition; Base Sequence; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Diglycerides; Female; Fibrosarcoma; Genes, p53; Genes, ras; Mice; Mice, Transgenic; Molecular Sequence Data; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Cell-type-specific ras mutations but no microsatellite instability in chemically induced mouse skin tumors and transformed 3T3 cells.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinoma; Cell Transformation, Neoplastic; DNA Primers; DNA, Neoplasm; DNA, Satellite; Female; Fibrosarcoma; Genes, ras; Genetic Markers; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Papilloma; Point Mutation; Repetitive Sequences, Nucleic Acid; Skin Neoplasms | 1995 |
Changes in keratin expression during malignant progression of transformed mouse epidermal keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Transformation, Neoplastic; Genes, ras; Keratinocytes; Keratins; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Skin Neoplasms; Up-Regulation | 1993 |
Alterations in receptor-mediated kinases and phosphatases during carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cricetinae; Epidermal Growth Factor; Gonadotropin-Releasing Hormone; Mesocricetus; Mouth Mucosa; Phosphorylation; Precancerous Conditions; Protein Tyrosine Phosphatases; Receptor Protein-Tyrosine Kinases; Somatostatin; Time Factors; Up-Regulation | 1995 |
[Effect of candidal infection on the hyperplastic oral epithelium].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Candidiasis, Oral; Cell Transformation, Neoplastic; Cricetinae; Leukoplakia, Oral; Mesocricetus; Mouth Neoplasms; Precancerous Conditions | 1994 |
Sequential cytogenetic alterations in hamster oral keratinocytes during DMBA-induced oral carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; Cheek; Chromosome Aberrations; Cricetinae; Karyotyping; Keratinocytes; Mesocricetus; Mouth Neoplasms; Ploidies; Time Factors | 1994 |
Nucleolar organizer regions as a marker of incipient transformation in a model of experimental carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Female; Keratoacanthoma; Mice; Mice, Inbred SENCAR; Nucleolus Organizer Region; Papilloma; Silver Staining; Skin Neoplasms | 1994 |
Hormone receptors and cathepsin D levels in human breast epithelial cells transformed by chemical carcinogens and c-Ha-ras transfection.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Breast; Breast Neoplasms; Cathepsin D; Cell Line, Transformed; Cell Transformation, Neoplastic; Chemotaxis; Clone Cells; Epithelium; ErbB Receptors; Female; Genes, ras; Humans; Mice; Mice, SCID; Neoplasm Invasiveness; Receptors, Cell Surface; Receptors, Estrogen; Receptors, Progesterone; Transfection; Transplantation, Heterologous | 1994 |
Enhanced cytochrome P450 (Cyp1b1) expression, aryl hydrocarbon hydroxylase activity, cytotoxicity, and transformation of C3H 10T1/2 cells by dimethylbenz(a)anthracene in conditioned medium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Cell Count; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Culture Media; Culture Media, Conditioned; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; DNA; Fibroblasts; Mice; Mice, Inbred C3H | 1994 |
Increased expression of specific protein tyrosine phosphatases in human breast epithelial cells neoplastically transformed by the neu oncogene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Blotting, Southern; Breast; Cell Division; Cell Transformation, Neoplastic; Epithelium; Female; Gene Expression; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Leukocyte Common Antigens; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Molecular Sequence Data; Oncogenes; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2 | 1993 |
Cell lines from grc congenic strains of rats having different susceptibilities to chemical carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Cell Adhesion; Cell Division; Cell Line, Transformed; Cell Survival; Cell Transformation, Neoplastic; Female; Fibroblasts; Gene Deletion; Histocompatibility Antigens Class I; Male; Methylnitronitrosoguanidine; Polymorphism, Restriction Fragment Length; Rats | 1993 |
Evaluation of porfimer sodium fluorescence for measuring tissue transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bombesin; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Dihematoporphyrin Ether; Disease Models, Animal; Fluorescence; Mesocricetus; Mouth Neoplasms; Peptide Fragments; Photometry; Protein-Tyrosine Kinases; Somatostatin | 1993 |
Cellular kinetics and lectin distribution in hamster buccal carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Cheek; Cricetinae; Epithelium; Hyperplasia; Immunoenzyme Techniques; Lectins; Male; Mouth Mucosa; Mouth Neoplasms; Papilloma; Protein Binding | 1994 |
Experimental down-regulation of intermediate biomarkers of carcinogenesis in mouse mammary epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers; Cell Line; Cell Transformation, Neoplastic; DNA Repair; Down-Regulation; Epithelium; Estradiol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL | 1993 |
7,12-Dimethylbenz[a]anthracene-induced mouse keratinocyte malignant transformation independent of Harvey ras activation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Gene Expression Regulation; Genes, ras; Keratinocytes; Mice; Molecular Probes; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction | 1993 |
Activation of ribosomal protein S2 gene expression in a hamster model of chemically induced oral carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cricetinae; Disease Models, Animal; Gene Expression; Genes, ras; Male; Mesocricetus; Mouth Neoplasms; Ribosomal Proteins; Tumor Cells, Cultured | 1993 |
Immortalization phenotype dissociated from the preneoplastic phenotype in mouse mammary epithelial outgrowths in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Epithelium; Female; Genes, p53; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Ovariectomy; Phenotype; Precancerous Conditions | 1993 |
Reversal of cytochrome P-4501A1 and P-450-EF expression in MCA-C3H/10T1/2 cell-derived tumors as compared to cultured cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Cell Transformation, Neoplastic; Cells, Cultured; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Female; Immunohistochemistry; Isoenzymes; Methylcholanthrene; Mice; Mice, Nude; Neoplasms, Experimental; Tumor Cells, Cultured | 1993 |
Studies on acute myelomonocytic leukemia in LBF1 rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Gene Expression; Genes, myc; Immunohistochemistry; Leukemia, Myelomonocytic, Acute; Male; Neoplasm Transplantation; Oncogene Protein p21(ras); Rats | 1993 |
Carcinogenesis in human skin grafted to SCID mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Carcinogens; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Humans; Keratins; Ki-67 Antigen; Mice; Mice, SCID; Neoplasm Proteins; Nuclear Proteins; Papilloma; Skin Neoplasms; Skin Transplantation; Tetradecanoylphorbol Acetate; Transplantation, Heterologous; Ultraviolet Rays | 1996 |
Expression of Mad, an antagonist of Myc oncoprotein function, in differentiating keratinocytes during tumorigenesis of the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Carcinogens; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Differentiation; Cell Transformation, Neoplastic; DNA-Binding Proteins; Epidermal Cells; Epidermis; Gene Expression; Humans; Immunohistochemistry; In Situ Hybridization; Keratinocytes; Mice; Mice, Inbred Strains; Proto-Oncogene Proteins c-myc; Repressor Proteins; RNA Probes; Skin; Skin Neoplasms | 1996 |
Growth pattern of experimental squamous cell carcinoma in rat submandibular glands--an immunohistochemical evaluation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Female; Immunoenzyme Techniques; Male; Rats; Rats, Sprague-Dawley; Submandibular Gland; Submandibular Gland Neoplasms; Time Factors | 1996 |
Vitamin E inhibits experimental carcinogenesis and tumour angiogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cricetinae; Drug Screening Assays, Antitumor; Immunoenzyme Techniques; Male; Mesocricetus; Neoplasms, Experimental; Neovascularization, Pathologic; Transforming Growth Factor alpha; Vitamin E | 1996 |
Localization and treatment of transformed tissues using the photodynamic sensitizer 2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cheek; Chlorophyll; Cricetinae; Fluorescence; Lasers; Male; Mesocricetus; Neoplasms, Experimental; Photochemotherapy; Photosensitizing Agents | 1996 |
AgNOR mark epithelial foci in malignant transformation in hamster cheek pouch carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cell Nucleus; Cell Transformation, Neoplastic; Cheek; Coloring Agents; Cricetinae; Disease Progression; Epithelium; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Nucleolus Organizer Region; Silver | 1996 |
Studies on promoting activity of Taiwan betel quid ingredients in hamster buccal pouch carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Areca; Cell Transformation, Neoplastic; Cheek; Cocarcinogenesis; Cricetinae; Male; Mesocricetus; Mouth Neoplasms; Plant Extracts; Plants, Medicinal | 1996 |
The effects of platelet-derived growth factor-BB and insulin-like growth factor-1 on epithelial dysplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Becaplermin; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cheek; Chi-Square Distribution; Cricetinae; Epithelium; Female; gamma-Glutamyltransferase; Growth Substances; Histocytochemistry; Insulin-Like Growth Factor I; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Platelet-Derived Growth Factor; Precancerous Conditions; Proto-Oncogene Proteins c-sis; Regression Analysis; Statistics, Nonparametric | 1996 |
Prevention of mammary preneoplastic transformation by naturally-occurring tumor inhibitors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Genes, myc; Genes, ras; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mice; Precancerous Conditions; Transfection; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1997 |
Carcinogenic polycyclic aromatic hydrocarbons increase intracellular Ca2+ and cell proliferation in primary human mammary epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzo(a)pyrene; Benzoflavones; Breast; Breast Neoplasms; Calcium; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Female; Homeostasis; Humans; Intracellular Fluid; Polychlorinated Dibenzodioxins; Polycyclic Aromatic Hydrocarbons | 1997 |
Combined effects of dehydroepiandrosterone and EM-800 on bone mass, serum lipids, and the development of dimethylbenz(A)anthracene-induced mammary carcinoma in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaline Phosphatase; Animals; Benzopyrans; Bone Density; Calcium; Carcinogens; Cell Transformation, Neoplastic; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Estradiol; Estrogen Antagonists; Female; Genitalia, Female; Lipids; Luteinizing Hormone; Mammary Neoplasms, Experimental; Organ Size; Phosphorus; Prolactin; Propionates; Random Allocation; Rats; Rats, Sprague-Dawley | 1997 |
Induction of PA2.26, a cell-surface antigen expressed by active fibroblasts, in mouse epidermal keratinocytes during carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Keratinocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microscopy, Fluorescence; Skin; Skin Neoplasms; Stromal Cells | 1997 |
Characterization of native fluorescence from DMBA-treated hamster cheek pouch buccal mucosa for measuring tissue transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cheek; Cricetinae; Fluorescence; Mesocricetus; Mouth Mucosa | 1998 |
Verification in syngeneic hamsters of in vitro transformation of hamster oral mucosa by 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Culture Techniques; Cell Cycle; Cell Transformation, Neoplastic; Cheek; Cricetinae; Dose-Response Relationship, Drug; Keratinocytes; Keratins; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Neoplasm Transplantation | 1997 |
Diagnosis of head and neck precancerous lesions in an animal model using fluorescence spectroscopy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma in Situ; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Color; Cricetinae; Disease Models, Animal; Disease Progression; Fluorescence; Follow-Up Studies; Hyperplasia; Lasers; Leukoplakia, Oral; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Neoplasm Invasiveness; Precancerous Conditions; Spectrometry, Fluorescence; Stomatitis | 1998 |
Polyamines regulate expression of the neoplastic phenotype in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Apoptosis; Carcinoma, Papillary; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Eflornithine; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ornithine Decarboxylase; Polyamines; Putrescine; Skin; Skin Neoplasms; Spermidine; Spermine | 1998 |
A Bcl-xL transgene promotes malignant conversion of chemically initiated skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; bcl-X Protein; Carcinogens; Cell Transformation, Neoplastic; Disease Progression; Mice; Mice, Transgenic; Papilloma; Proto-Oncogene Proteins c-bcl-2; Skin Neoplasms; Transgenes | 1998 |
Skin tumor development and keratin expression in different experimental models. Relation to inducing agent and target tissue structure.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Keratins; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Skin Neoplasms | 1998 |
Analysis of ras gene mutational spectra in epidermal papillomas from K6/ODC transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; DNA Primers; Genes, ras; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Ornithine Decarboxylase; Papilloma; Skin Neoplasms | 1998 |
Spontaneous and asbestos-induced transformation of mesothelial cells in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Asbestos; Benzo(a)pyrene; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Insulin; Insulin-Like Growth Factor I; Pleura; Rats; Rats, Wistar | 1998 |
Inhibition of DMBA-initiated rat mammary tumour development by 1-O-hexyl-2,3,5-trimethylhydroquinone, phenylethyl isothiocyanate, and novel synthetic ascorbic acid derivatives.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Carcinogens; Cell Transformation, Neoplastic; Chemoprevention; Diet; Female; Hydroquinones; Isothiocyanates; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1998 |
The augmentation of melanocytic nevi in guinea pigs by solar-simulated light: an animal model for human melanocytic nevi.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Deoxyribodipyrimidine Photo-Lyase; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Male; Nevus, Pigmented; Sunlight | 1998 |
Comparative study of AgNOR and PCNA in experimental carcinogenesis of salivary glands of rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogens; Cell Division; Cell Nucleus; Cell Transformation, Neoplastic; Coloring Agents; Immunoenzyme Techniques; Nucleolus Organizer Region; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Silver; Submandibular Gland; Submandibular Gland Neoplasms; Time Factors | 1997 |
In vitro growth changes of oral human keratinocytes after treatment with carotenoids, retinoid, and/or DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Animals; Anticarcinogenic Agents; beta Carotene; Canthaxanthin; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; Diterpenes; Flow Cytometry; Gene Expression Regulation; Humans; Immunohistochemistry; Keratinocytes; Male; Mice; Mice, Nude; Mouth Mucosa; Mouth Neoplasms; Retinyl Esters; Vitamin A | 1999 |
Effect of vitamin D3 on carcinogen-modified liver enzymes and tumour incidence in experimental rat mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cholecalciferol; Female; Glutathione Transferase; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley | 1999 |
Promotional effects of CO2 laser on DMBA-induced hamster buccal pouch carcinogenesis as shown by immunohistochemistry of the placental form of glutathione S-transferase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cricetinae; Glutathione Transferase; Immunohistochemistry; Laser Therapy; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms | 1999 |
Perchloric acid-soluble proteins from goat liver inhibit chemical carcinogenesis of Syrian hamster cheek-pouch carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cheek; Cricetinae; Dexamethasone; Goats; Liver; Male; Mesocricetus; Mouth Neoplasms; Perchlorates; Proteins; Solubility | 1999 |
Tumor suppression by p27Kip1 and p21Cip1 during chemically induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Carcinogens; Carcinoma; Cell Cycle Proteins; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Genes, ras; Genes, Tumor Suppressor; Intestinal Neoplasms; Keratinocytes; Mice; Mice, Knockout; Microtubule-Associated Proteins; Mutation; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins | 1999 |
A multihit, multistage model of chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA Mutational Analysis; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Keratinocytes; Keratins; Mice; Models, Biological; Neoplasm Proteins; Papilloma; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; S Phase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Tea preparations protect against DMBA-induced oral carcinogenesis in hamsters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Anticarcinogenic Agents; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cricetinae; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Male; Mouth Mucosa; Mouth Neoplasms; Random Allocation; Tea | 1999 |
Endocrine characteristics of human breast epithelial cells, MCF-10F.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aromatase; Aryl Hydrocarbon Hydroxylases; Breast; Breast Neoplasms; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Epithelial Cells; Estradiol; Estriol; Female; Humans; Hydroxyestrones; Steroid 16-alpha-Hydroxylase; Tumor Cells, Cultured | 1999 |
Surface changes and hormone production in pituitary cells during tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acridines; Adrenocorticotropic Hormone; alpha-MSH; Animals; Carcinogens; Cell Transformation, Neoplastic; Estrone; Female; Growth Hormone; Pituitary Gland, Anterior; Pituitary Neoplasms; Prolactin; Prolactinoma; Rats; Rats, Wistar; Tumor Cells, Cultured | 1999 |
Expression of bone sialoprotein in mineralized tissues of tooth and bone and in buccal-pouch carcinomas of Syrian golden hamsters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Base Sequence; Bone and Bones; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Disease Models, Animal; Gene Expression Regulation; Integrin-Binding Sialoprotein; Male; Mesocricetus; Molecular Sequence Data; Mouth Mucosa; Mouth Neoplasms; Random Allocation; Sialoglycoproteins; Tooth | 2000 |
Aneuploidy precedes and segregates with chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Carcinogens; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Cricetulus; Cytarabine; DNA Mutational Analysis; Humans; Karyotyping; Male; Methylcholanthrene; Models, Biological; Neoplasms, Experimental; Precancerous Conditions; Time Factors | 2000 |
Morphological phenotypes in neoplastic progression of human breast epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast; Breast Neoplasms; Cell Transformation, Neoplastic; Epithelial Cells; Female; Genes, ras; Humans; Mice; Mice, SCID; Microscopy, Electron, Scanning; Transfection | 2000 |
Aberrant cell cycle progression contributes to the early-stage accelerated carcinogenesis in transgenic epidermis expressing the dominant negative TGFbetaRII.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinogens; Carcinoma, Squamous Cell; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Transformation, Neoplastic; Centrosome; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p27; Epidermal Cells; Gene Expression; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Mitosis; Papilloma; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Tetradecanoylphorbol Acetate; Time Factors; Tumor Suppressor Proteins | 2000 |
Effect of gynostemma pentaphyllum mak on carcinomatous conversions of golden hamster cheek pouches induced by dimethylbenzanthracene: a histological study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Carcinogens; Carcinoma in Situ; Cell Transformation, Neoplastic; Cheek; Cricetinae; Cucurbitaceae; Drugs, Chinese Herbal; Leukoplakia, Oral; Mesocricetus; Mouth Neoplasms; Phytotherapy; Random Allocation | 1998 |
Cancer induction in the DMBA hamster cheek pouch: a modified technique using a promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arecoline; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Disease Models, Animal; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Sutures | 2001 |
[p53 gene mutations in mouse skin tumors induced by DMBA-TPA-MNNG].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Exons; Genes, p53; Methylnitronitrosoguanidine; Mice; Mice, Inbred SENCAR; Papilloma; Point Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Quantitative assay for carcinogen altered differentiation in mouse epidermal cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcium; Carcinogens; Cell Adhesion; Cell Differentiation; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Coculture Techniques; Coloring Agents; Dose-Response Relationship, Drug; Epidermal Cells; Epidermis; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Phenotype; Rhodamines; Staining and Labeling | 1980 |
Smads mediate signaling of the TGFbeta superfamily in normal keratinocytes but are lost during skin chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; Keratinocytes; Mice; Mice, Inbred ICR; Protein Transport; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Skin Neoplasms; Transcription Factors; Transforming Growth Factor beta | 2001 |
Cancer chemopreventive activities of S-3-1, a synthetic derivative of danshinone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Benzofurans; Bepridil; Biphenyl Compounds; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Croton Oil; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Epithelial Cells; Fibroblasts; Free Radical Scavengers; Hypoxanthine; In Vitro Techniques; Iron; Lipid Peroxidation; Lung; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred ICR; Microsomes, Liver; Molecular Structure; Mutagens; Ornithine; Ornithine Decarboxylase; Papilloma; Pentetic Acid; Phenanthrenes; Picrates; Plants, Medicinal; Rats; Salmonella; Skin; Skin Neoplasms; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Xanthine Oxidase | 2001 |
High susceptibility of transgenic rats carrying the human c-Ha-ras proto-oncogene to chemically-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Genetically Modified; Carcinogens; Cell Transformation, Neoplastic; Female; Genes, ras; Genetic Predisposition to Disease; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Polymorphism, Single-Stranded Conformational; Proto-Oncogene Mas; Rats | 2001 |
Influence of beta1 integrins on epidermal squamous cell carcinoma formation in a transgenic mouse model: alpha3beta1, but not alpha2beta1, suppresses malignant conversion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Antigens, Neoplasm; Basigin; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Female; Integrin alpha3beta1; Integrins; Keratinocytes; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Papilloma; Receptors, Collagen; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tetraspanin 28 | 2001 |
Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p16; Embryo, Mammalian; Female; Fibroblasts; Gene Deletion; Genes, p16; Genes, ras; Genetic Predisposition to Disease; Humans; Male; Melanoma, Experimental; Mice; Point Mutation; Proteins; Tumor Suppressor Protein p14ARF | 2001 |
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Embryo, Mammalian; Female; Fibroblasts; Gene Deletion; Gene Targeting; Genes, p16; Genetic Predisposition to Disease; Male; Mice; Mice, Knockout; Neoplasms; Proteins; T-Lymphocytes; Thymus Gland; Tumor Suppressor Protein p14ARF; Urethane | 2001 |
Discrete roles of cytokines, TNF-alpha, IL-1, IL-6 in tumor promotion and cell transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; DNA Primers; Female; Humans; Interleukin-1; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Okadaic Acid; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha | 2002 |
Functional roles of Akt signaling in mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Nucleus; Cell Transformation, Neoplastic; Cyclin D1; Cytoplasm; Enzyme Activation; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Keratinocytes; MAP Kinase Signaling System; Mice; Mice, Inbred SENCAR; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Papilloma; Phosphatidylinositol 3-Kinases; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Skin Neoplasms; Tumor Suppressor Proteins | 2002 |
Constituents of the bark and twigs of Artocarpus dadah with cyclooxygenase inhibitory activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylation; Animals; Benzofurans; Breast; Catechin; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Indonesia; Isoenzymes; Membrane Proteins; Methylation; Mice; Mice, Inbred BALB C; Molecular Structure; Moraceae; Nuclear Magnetic Resonance, Biomolecular; Organ Culture Techniques; Plant Bark; Plant Extracts; Plant Shoots; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Stilbenes | 2002 |
JunB negatively regulates AP-1 activity and cell proliferation of malignant mouse keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Electroporation; Gene Expression Regulation; Keratinocytes; Kinetics; Mice; Oligodeoxyribonucleotides, Antisense; Proto-Oncogene Proteins c-jun; Recombinant Proteins; Skin Neoplasms; Transcription Factor AP-1; Transcriptional Activation; Transfection | 2002 |
Inhibitory effects of estrogenic compounds, 4-nonylphenol and genistein, on 7,12-dimethylbenz[a]anthracene-induced ovarian carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Administration, Oral; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Female; Genistein; Ovarian Neoplasms; Phenols; Rats; Rats, Sprague-Dawley | 2002 |
Effect of selective ablation of proliferating mammary epithelial cells on MNU induced rat mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoviridae; Animals; Antiviral Agents; beta-Galactosidase; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Ganciclovir; Gene Expression Regulation, Developmental; Immunoenzyme Techniques; Incidence; Injections, Intralesional; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred WF; Thymidine Kinase | 2002 |
Expression of an early, nonstructural antigen of herpes simplex virus in cell transformed in vitro by herpes simplex virus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoviruses, Human; Antigens, Viral; Cell Line; Cell Transformation, Neoplastic; Cytoplasm; DNA, Neoplasm; Epitopes; Fluorescent Antibody Technique; Mitosis; Peptides; Simian virus 40; Simplexvirus | 1977 |
Malignant transformation of a mouse epithelial cell line with polycyclic aromatic hydrocarbons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzopyrenes; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; Epithelium; Methylcholanthrene; Polycyclic Compounds | 1978 |
Biological influence of fat intake on mammary cancer and mammary tissue: experimental correlates.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast; Breast Neoplasms; Cell Transformation, Neoplastic; Dietary Fats; Neoplasms, Experimental; Prolactin; Rats | 1978 |
Cellular uptake, transport, and macromolecular binding of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene by human cells in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benz(a)Anthracenes; Benzopyrenes; Biological Transport, Active; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; Cytoplasm; Humans; Protein Binding; Time Factors | 1978 |
Neoplastic transformation of rat mammary cells exposed to 7,12-dimethylbenz[alpha]anthracene or N-nitrosomethylurea in cell culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Cells, Cultured; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Rats | 1978 |
Factors affecting the binding of polycyclic aromatic hydrocarbons to human embryo cells, and transformable and non-transformable hamster embryo cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA; Embryo, Mammalian; Humans; Mesocricetus; Polycyclic Compounds; Protein Binding; RNA | 1978 |
Two-stage (initiation-promotion) carcinogenesis in vivo and in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Croton Oil; Female; In Vitro Techniques; Mice; Models, Biological; Neoplasms, Experimental; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1978 |
Characteristics of chemically transformed mouse epidermal cells in vitro and in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cell Transformation, Neoplastic; Cells, Cultured; In Vitro Techniques; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Skin Neoplasms; Transplantation, Homologous | 1978 |
Induction of malignant transformation and mutagenesis by dihydrodiols derived from 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benz(a)Anthracenes; Cell Line; Cell Transformation, Neoplastic; Mutation; Structure-Activity Relationship | 1978 |
Alkaline phosphatase as a marker of transformation in adult mouse bladder epithelium after in vitro exposure to 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaline Phosphatase; Animals; Benz(a)Anthracenes; Cell Line; Cell Transformation, Neoplastic; Culture Techniques; Epithelium; Mice; Mitochondria; Urinary Bladder | 1978 |
Cultivation of human adult skin fibroblasts & induction of malignant transformation with 7, 12-dimethylbenz(e) anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Humans; Skin | 1978 |
Effects of donor age on neoplastic transformation of adult mouse bladder epithelium in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Aging; Animals; Cell Transformation, Neoplastic; Culture Techniques; Epithelium; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Isogeneic; Urinary Bladder Neoplasms | 1979 |
The oncogenic potential of three different 7,12-dimethylbenz(a)anthracene transformed C3H/10T1/2 cell clones at various passages and the importance of the mode of immunosuppression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antilymphocyte Serum; Benz(a)Anthracenes; Cell Line; Cell Transformation, Neoplastic; Embryo, Mammalian; Female; Immunity; Immunosuppression Therapy; Male; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Sarcoma, Experimental; T-Lymphocytes; Transplantation, Isogeneic | 1979 |
Phenotypic properties and tumor promotor-induced alterations in rat embryo cells transformed by adenovirus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoviruses, Human; Animals; Benzopyrenes; Cell Aggregation; Cell Division; Cell Transformation, Neoplastic; Cell Transformation, Viral; Clone Cells; Cocarcinogenesis; Concanavalin A; Embryo, Mammalian; Membrane Proteins; Phenotype; Phorbols; Plasminogen Activators; Rats; Tetradecanoylphorbol Acetate | 1979 |
Apurinic acid endonuclease activity from mouse epidermal cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apurinic Acid; Cell Line; Cell Transformation, Neoplastic; Deoxyribonucleases; Endonucleases; Kinetics; Mice; Molecular Weight; Polynucleotides; Skin; Substrate Specificity | 1979 |
Differential rotational mobility of a membrane-bound fluorochrome in cell types of increasing oncogenic potential.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Cell Transformation, Neoplastic; Fluorescent Dyes; Membrane Fluidity; Membrane Lipids; Methylcholanthrene; Mice; Phosphatidylcholines; Temperature | 1979 |
Comparison of mutagenesis and malignant transformation by dihydrodiols from benz[a]anthracene and 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Fibroblasts; Mice; Mutagens | 1979 |
Transformation of feline embryo cells in culture by a chemical carcinogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cats; Cell Aggregation; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Culture Media; Dimethyl Sulfoxide; Embryo, Mammalian; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental | 1979 |
Biochemical basis for cytotoxicity of 7,12-dimethylbenz(a)anthracene in rat liver epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Drug Resistance; Epithelium; Inactivation, Metabolic; Liver; Liver Neoplasms, Experimental; Rats | 1979 |
The surface structure of 7,12-dimethylbenz(a)anthracene transformed C3H/10T 1/2 cells. A quantitative scanning electron microscopical study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Fibroblasts; Mice; Mice, Inbred C3H; Microscopy, Electron, Scanning; Microvilli | 1979 |
Reduction in the formation of carcinogen-induced transformed foci by pencillin G sodium in the C3H/10T1/2 CL8 cell lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Division; Cell Line; Cell Transformation, Neoplastic; Culture Media; Gentamicins; Methylcholanthrene; Mice; Penicillin G; Streptomycin; X-Rays | 1979 |
Neoplastic transformation of epithelial cells in whole mammary gland in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Culture Media; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Organ Culture Techniques | 1979 |
Retinoid prevents mammary gland transformation by carcinogenic hydrocarbon in whole-organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Retinoids; Vitamin A | 1979 |
Anti-inflammatory consequences of transplanted tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Movement; Cell Transformation, Neoplastic; Chemotaxis; Fibrosarcoma; Inflammation; Macrophages; Monocytes; Neoplasm Transplantation; Peptones; Rats | 1979 |
Protective effect of dehydroepiandrosterone against aflatoxin B1-and 7,12-dimethylbenz(a)anthracene-induced cytotoxicity and transformation in cultured cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxins; Animals; Benz(a)Anthracenes; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dehydroepiandrosterone; Epithelial Cells; Epithelium; Etiocholanolone; Liver; Male; Rats; Testosterone; Thymidine; Time Factors | 1975 |
Cytological and cytophotometric studies on DMBA--induced changes of the conjunctival epithelium in Syrian golden hamsters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Nucleus; Cell Transformation, Neoplastic; Conjunctiva; Cricetinae; Cytological Techniques; DNA; Epithelial Cells; Epithelium; Female; Karyometry; Photometry | 1977 |
Tumor persistence and regression in skin carcinogenesis. An experimental study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Mice; Neoplasm Regression, Spontaneous; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1978 |
Endogenous oncornaviruses in chemically induced transformation. I. Transformation independent of virus production.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Benz(a)Anthracenes; Cell Line; Cell Transformation, Neoplastic; Clone Cells; DNA Nucleotidyltransferases; Fibroblasts; Fluorescent Antibody Technique; Idoxuridine; Kinetics; Leukemia Virus, Murine; Mammary Tumor Virus, Mouse; Methylcholanthrene; Mice; Mice, Inbred AKR; Mice, Inbred C3H; Viral Plaque Assay; Virus Replication | 1975 |
Surface morphology of normal and neoplastic rat cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alpharetrovirus; Animals; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Humans; Methylcholanthrene; Neoplasms, Experimental; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1977 |
Comparative studies on isoaccepting arginyl tRNAs from transformed cells and their utilization in post-translational protein modification.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Arginine; Cell Line; Cell Transformation, Neoplastic; Methylcholanthrene; Neoplasm Proteins; Polyomavirus; Proteins; RNA, Neoplasm; RNA, Transfer; Simian virus 40 | 1977 |
Considerations on the preneoplastic lesions of the mammary gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast; Breast Neoplasms; Bromocriptine; Cell Transformation, Neoplastic; Cells, Cultured; Ergolines; Female; Humans; Hyperplasia; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Neoplasm Transplantation; Precancerous Conditions; Transplantation, Heterologous; Urethane | 1977 |
Murine mammary tumor virus expression during mammary tumorigenesis in BALB/c mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Cell Transformation, Neoplastic; Hormones; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred BALB C; Nucleic Acid Hybridization; RNA, Viral | 1979 |
Leukemogenesis by an endogenous virus isolated from the CFW mouse. II. Early effects of virus on thymus gland and bone marrow cell populations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bone Marrow; Cell Transformation, Neoplastic; Cells, Cultured; Female; Leukemia Virus, Murine; Leukemia, Experimental; Lymphoma; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; T-Lymphocytes; Thymus Gland; Thymus Neoplasms; Transplantation, Isogeneic; Tumor Virus Infections | 1979 |
Effects of serum concentration on the expression of carcinogen-induced transformation in the C3H/10T1/2 CL8 cell line.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Culture Media; Mice; Time Factors | 1977 |
Angiogenesis: a marker for neoplastic transformation of mammary papillary hyperplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Hyperplasia; Iris; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Papilloma; Transplantation, Heterologous; Urethane | 1977 |
Establishment and characteristics of three mouse cell lines from embryos of different inbred strains.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Cell Division; Cell Line; Cell Transformation, Neoplastic; Contact Inhibition; Karyotyping; Methylnitronitrosoguanidine; Mice; Mice, Inbred AKR; Mice, Inbred C3H; Mice, Inbred Strains; Species Specificity | 1977 |
Two-stage carcinogenesis with rat embryo cells in tissue culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzopyrenes; Cell Transformation, Neoplastic; Clone Cells; Croton Oil; Fibroblasts; Neoplasms, Experimental; Phorbol Esters; Phorbols; Rats | 1977 |
Hamster cells, untreated and treated with chemical carcinogens, maintained in vitro for 2 1/2 years.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Brain; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Embryo, Mammalian; Lung; Neoplasm Transplantation; Time Factors; Transplantation | 1977 |
Clonal behavior of a rat liver cell line and its modification by repeated treatments with a carcinogenic polycyclic hydrocarbon.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chromosomes; Clone Cells; Enzyme Induction; Epithelial Cells; Epithelium; Liver; Serum Albumin | 1977 |
The activity of 7-methylbenz(a)anthracene metabolites in an in vitro-in vivo carcinogenicity test using mouse lung tissue.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Benz(a)Anthracenes; Carcinogens; Cell Transformation, Neoplastic; Female; In Vitro Techniques; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Isogeneic | 1977 |
Stages in neoplastic transformation of adult epithelial cells by 7,12-dimethylbenz(a)anthracene in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Cell Line; Cell Transformation, Neoplastic; Epithelium; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Submandibular Gland; Time Factors; Transplantation, Isogeneic | 1977 |
Epidermal intercellular relationships during carcinogenesis and cocarcinogenesis as revealed by scanning electron microscopy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Autoradiography; Cell Transformation, Neoplastic; Cocarcinogenesis; Epithelium; Extracellular Space; Female; Hyperplasia; Intercellular Junctions; Mice; Microscopy, Electron, Scanning; Skin; Tetradecanoylphorbol Acetate | 1977 |
[A study of experimental ovarian tumors. Consideration of tumorigenetic process with a chemical carcinogen, 7, 12-dimethylbenzanthracene (author's transl)].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Cystadenocarcinoma; Cystadenoma; Female; Ovarian Neoplasms; Rats; Sarcoma, Experimental | 1977 |
Chemical transformation of human revertant cells induced by murine sarcoma virus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Agar; Benzopyrenes; Carcinogens; Cell Aggregation; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cytotoxicity Tests, Immunologic; Humans; Methylcholanthrene; Polycyclic Compounds | 1978 |
Origin of tubular complexes developing during induction of pancreatic adenocarcinoma by 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Female; Male; Neoplasms, Experimental; Pancreas; Pancreatic Neoplasms; Rats | 1978 |
Gangliosides and their cell density-dependent changes in control and chemically transformed C3H/10T1/2 cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Cell Communication; Cell Count; Cell Division; Cell Line; Cell Transformation, Neoplastic; G(M3) Ganglioside; Gangliosides; Glucosamine; Methylcholanthrene | 1978 |
[Change in acetylation activity in 7,12-dimethylbenz(alpha)-anthracene induction].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetylation; Acetyltransferases; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Enzyme Activation; Female; Liver; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Sarcoma, Experimental; Skin Neoplasms | 1978 |
Biochemical activation of aryl hydrocarbon hydroxylase activity, cellular distribution of polynuclear hydrocarbon metabolites, and DNA damage by polynuclear hydrocarbon products in human cells in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA Repair; Enzyme Induction; Humans; Methylcholanthrene; Polycyclic Compounds | 1978 |
Stimulation of malignant skin cells by antibody to normal skin cells of mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Antibodies; Cell Transformation, Neoplastic; Cells, Cultured; Cytotoxicity Tests, Immunologic; Fluorescent Antibody Technique; Graft Survival; Immune Sera; Neoplasm Transplantation; Skin; Skin Neoplasms | 1978 |
In vitro development of oncogenicity in cell lines established from tracheal epithelium preexposed in vivo to 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Agar; Animals; Benz(a)Anthracenes; Cell Line; Cell Transformation, Neoplastic; Culture Media; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Time Factors; Tracheal Neoplasms; Transplantation, Isogeneic | 1978 |
Neoantigens on chemically transformed cloned C3H mouse embryo cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Cell Transformation, Neoplastic; Cells, Cultured; Cytotoxicity Tests, Immunologic; Female; Fluorescent Antibody Technique; Immunity, Cellular; Male; Methylcholanthrene; Mice; Mice, Inbred C3H; Pregnancy | 1975 |
Effects of 7,12-dimethylbenz(a)anthracene on rat mammary epithelial cell macromolecules: a time study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Nucleus; Cell Transformation, Neoplastic; Cytosol; DNA; Epithelial Cells; Epithelium; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Proteins; Rats; RNA; Time Factors | 1975 |
[Carcinogenic effect of 7,12-dimethylbenz(a)anthracene 5,6-oxide in mice].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benz(a)Anthracenes; Carcinogens; Cell Transformation, Neoplastic; Epoxy Compounds; Female; Fibrosarcoma; Hemangioma; Injections, Subcutaneous; Male; Osteoma, Osteoid; Papilloma; Skin; Skin Neoplasms | 1975 |
Cytogenetic analysis of oral and cutaneous squamous cell carcinomas in the rat.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Chromosome Aberrations; Culture Techniques; Karyotyping; Mouth Neoplasms; Rats; Skin Neoplasms | 1975 |
Transformation of human osteosarcoma cells by a chemical carcinogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Dimethyl Sulfoxide; Mice; Mice, Nude; Neoplasms, Experimental; Osteosarcoma | 1975 |
Surface proteins and fibrinolytic activity of cultured mammalian cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Carcinoma; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Fibrinolysis; Glycoproteins; Methylcholanthrene; Neoplasms, Experimental; Oncogenic Viruses; Plasminogen; Sarcoma; Urinary Bladder Neoplasms | 1976 |
Significance of treatment interval and DNA repair in the enhancement of viral transformation by chemical carcinogens and mutagens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetoxyacetylaminofluorene; Adenoviridae; Aflatoxins; Benzopyrenes; Caffeine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cytarabine; DNA Repair; DNA Replication; Methyl Methanesulfonate; Methylcholanthrene; Methylnitronitrosoguanidine; Mutagens; Oncogenic Viruses; Propiolactone | 1976 |
In vitro malignant transformation of mouse fibroblasts by non-K-region dihydrodiols derived from 7-methylbenz(a)anthracene, 7,12-dimethylbenz(a)anthracene, and benzo(a)pyrene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Glycols; Mice; Sarcoma, Experimental | 1976 |
Two-stage chemical oncogenesis in cultures of C3H/10T1/2 cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Drug Administration Schedule; Methylcholanthrene; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1976 |
Fate of early carcinogen-induced lesions in tracheal epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Epithelium; Hyperplasia; Neoplasms, Experimental; Precancerous Conditions; Rats; Time Factors; Tracheal Neoplasms | 1976 |
The effect of methotrexate on experimental salivary gland neoplasm in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Female; Male; Methotrexate; Neoplasms, Experimental; Rats; Salivary Gland Neoplasms; Stimulation, Chemical; Time Factors | 1975 |
The role of epidermal aryl hydrocarbon hydroxylase in the covalent binding of polycyclic hydrocarbon to DNA and its relationship to tumor initiation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Benzopyrenes; Binding Sites; Carcinogens; Cell Transformation, Neoplastic; DNA; Male; Methylcholanthrene; Mice; Skin | 1976 |
Heterogeneity in in vitro response to progesterone and melphalan of mammary tumours induced in the rat by 7,12-DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Cells, Cultured; Female; Mammary Neoplasms, Experimental; Melphalan; Progesterone; Rats | 1976 |
The developmental biology of induced malignant melanoma in guinea pigs and a comparison with other neoplastic systems.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Guinea Pigs; Humans; Hyperplasia; Male; Melanocytes; Melanoma; Neoplasm Metastasis; Neoplasms, Experimental; Rodentia; Time Factors | 1976 |
Scanning electron microscopy of in vitro chemically transformed mouse embryo cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Contact Inhibition; Methylcholanthrene; Microscopy, Electron, Scanning | 1976 |
Identification and quantification of a carcinogen-induced molecular initiation event in cell transformation.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Gene Expression; Genes, ras; Mice; Molecular Sequence Data; Mutation; Tetradecanoylphorbol Acetate | 1992 |
Phenotypic expression of carcinogen-initiated epidermal cells to tumor cells by 12-O-tetradecanoylphorbol-13-acetate in a manner dependent on 3T3 fibroblast-derived humoral factor(s).
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcium; Cell Transformation, Neoplastic; Cells, Cultured; Epidermis; Macrophages; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Abrogation of killing and neoplastic transformation of C3H10T1/2 cells due to 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoflavones; Cell Line; Cell Survival; Cell Transformation, Neoplastic; DNA; Mice | 1992 |
beta-Carotene-mediated inhibition of a DNA adduct induced by 7,12-dimethylbenz(a)anthracene and 7-hydroxymethyl-12-methylbenz(a)anthracene in mouse mammary gland in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Carotenoids; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C | 1992 |
c-Ha-ras gene mutation and activation precede pathological changes in DMBA-induced in vivo carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Cell Transformation, Neoplastic; Cricetinae; ErbB Receptors; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Genes, ras; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Tumor Cells, Cultured | 1992 |
Oncogene alterations in in vitro transformed rat tracheal epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; Cell Line; Cell Transformation, Neoplastic; DNA; Epithelium; Gene Amplification; Gene Rearrangement; Genes, ras; Male; Nucleic Acid Hybridization; Oncogene Protein p21(ras); Oncogenes; Polymorphism, Restriction Fragment Length; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Rats; RNA; Tetradecanoylphorbol Acetate; Trachea; Transfection | 1990 |
Sequential loss of suppressor genes for three specific functions during in vivo carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cornea; Cricetinae; Female; Hybridomas; Keratinocytes; Male; Neovascularization, Pathologic; Phenotype; Rats; Suppression, Genetic | 1990 |
Nonrandom duplication of the chromosome bearing a mutated Ha-ras-1 allele in mouse skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Cell Transformation, Neoplastic; Chromosome Mapping; Gene Amplification; Genes, ras; Immunoenzyme Techniques; Keratins; Mice; Mice, Inbred Strains; Models, Genetic; Mutation; Nucleic Acid Hybridization; Polymorphism, Restriction Fragment Length; Skin Neoplasms | 1990 |
Sequential loss of suppressor gene functions during in vivo carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Genes, Suppressor; Mouth Neoplasms; Neoplasms, Experimental; Neovascularization, Pathologic | 1990 |
TGF-beta 1 and skin carcinogenesis: antiproliferative effect in vitro and TGF-beta 1 mRNA expression during epidermal hyperproliferation and multistage tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Blotting, Northern; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA Replication; DNA, Neoplasm; Female; Gene Expression; Keratinocytes; Mice; Mice, Inbred Strains; Phorbol Esters; RNA; RNA, Messenger; RNA, Neoplasm; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1991 |
Decreased expression of the myristoylated alanine-rich C kinase substrate in transformed BALB/C 3T3 mouse fibroblasts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Blotting, Southern; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; DNA Probes; Fibroblasts; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins; Kirsten murine sarcoma virus; Membrane Proteins; Mice; Mice, Inbred BALB C; Myristoylated Alanine-Rich C Kinase Substrate; Protein Kinase C; Proteins; RNA; RNA, Messenger | 1991 |
Eosinophils, tissue eosinophilia, and eosinophil-derived transforming growth factor alpha in hamster oral carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cricetinae; Eosinophils; Gene Expression; Male; Mesocricetus; Mouth Neoplasms; Precancerous Conditions; RNA, Messenger; Transforming Growth Factor beta | 1992 |
Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Female; Hyperplasia; Mice; Neoplasm Metastasis; Neoplasms, Multiple Primary; Papilloma; Phorbol Esters; Skin; Skin Neoplasms; Urethane | 1991 |
[Genetics of cancerogenesis. Experimental model in mice].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Drug Resistance; Incidence; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phenotype; Tetradecanoylphorbol Acetate | 1991 |
Comparison of ras activation during epidermal carcinogenesis in vitro and in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcium; Carcinoma, Squamous Cell; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Culture Media; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Neoplasm Transplantation; Papilloma; Skin Neoplasms; Transfection; Tumor Cells, Cultured | 1991 |
Influence of diet on breast cancer size and morphology in rats treated with DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cell Division; Cell Transformation, Neoplastic; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methionine; Rats; Rats, Inbred Strains | 1991 |
Human chorionic gonadotropin and rat mammary cancer prevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Chorionic Gonadotropin; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1990 |
Use of intracellular H3 messenger RNA as a marker to determine the proliferation pattern of normal and 7,12-dimethylbenz[a]anthracene-transformed hamster oral epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cheek; Cricetinae; DNA Probes; Epithelial Cells; Epithelium; Histones; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Nucleic Acid Hybridization; RNA, Messenger | 1990 |
Papilloma and carcinoma production in DMBA-initiated, onion oil-promoted mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Allium; Animals; Carcinoma; Cell Transformation, Neoplastic; Female; Garlic; Mice; Papilloma; Plant Oils; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Evidence that weak promotion of carcinogen-initiated cells prevents their progression to malignancy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoflavones; Benzyl Alcohols; Cell Transformation, Neoplastic; Cortisone; Dose-Response Relationship, Drug; Indoles; Mice; Mice, Inbred BALB C; Papilloma; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin E | 1990 |
Identification of a serum-inducible messenger RNA (5B10) as the mouse homologue of calcyclin: tissue distribution and expression in metastatic, ras-transformed NIH 3T3 cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Base Sequence; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation, Viral; Chick Embryo; Fibroblasts; Gene Expression Regulation; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Transplantation; Oncogene Protein p21(ras); Organ Specificity; S100 Calcium Binding Protein A6; S100 Proteins; Simian virus 40; Species Specificity; Tetradecanoylphorbol Acetate | 1990 |
Immunohistochemical localization of keratin in experimental carcinoma of the mouse submandibular gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Epithelium; Histocytochemistry; Immunoenzyme Techniques; Keratins; Male; Metaplasia; Mice; Mice, Inbred Strains; Precancerous Conditions; Salivary Gland Neoplasms; Submandibular Gland; Submandibular Gland Neoplasms | 1986 |
Transfection of the EJ rasHa gene into keratinocytes derived from carcinogen-induced mouse papillomas causes malignant progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Keratins; Mice; Mice, Inbred Strains; Mice, Nude; Neoplasm Transplantation; Oncogenes; Papilloma; Skin | 1986 |
Enhanced expression and state of the c-myc oncogene in chemically and X-ray-transformed C3H/10T1/2 Cl 8 mouse embryo fibroblasts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bleomycin; Cell Line; Cell Transformation, Neoplastic; DNA Restriction Enzymes; Fibroblasts; Gene Expression Regulation; Methylcholanthrene; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Oncogenes; RNA, Neoplasm | 1987 |
Transforming growth factor alpha in chemically transformed hamster oral keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; Cloning, Molecular; Cricetinae; DNA Replication; Epidermal Cells; Epidermal Growth Factor; Epidermis; ErbB Receptors; Growth Substances; Keratins; Mouth Neoplasms; Peptides; Transforming Growth Factors | 1988 |
Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Carcinoma; Cell Transformation, Neoplastic; Female; Gene Expression Regulation; Genes; Keratins; Mice; Mice, Inbred Strains; Nucleic Acid Hybridization; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
Fate of 7,12-dimethylbenz(a)anthracene in the mouse mammary gland during initiation and promotion stages of carcinogenesis in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biological Transport; Carbon Radioisotopes; Cell Transformation, Neoplastic; DNA; DNA Damage; Female; Kinetics; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Organ Culture Techniques; Protein Biosynthesis | 1989 |
Sequential expression and cooperative interaction of c-Ha-ras and c-erbB genes in in vivo chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; Cell Transformation, Neoplastic; Cricetinae; Gene Expression Regulation; Genes, ras; Male; Membrane Proteins; Mice; Mice, Nude; Mouth Mucosa; Proto-Oncogene Proteins; Proto-Oncogenes; RNA, Neoplasm; Transcription, Genetic | 1989 |
Detection of Ki-ras messenger RNA in normal and chemically transformed hamster oral keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; Cell Cycle; Cell Transformation, Neoplastic; Cheek; Cricetinae; DNA, Neoplasm; Epidermal Cells; Epidermis; Hyperplasia; Mouth Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); RNA, Messenger; RNA, Neoplasm | 1989 |
A comparison of the effects of the prostaglandin synthesis inhibitors indomethacin and carprofen on 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis in rats fed different amounts of essential fatty acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cell Transformation, Neoplastic; Dietary Fats; Fatty Acids, Essential; Female; Indomethacin; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Prostaglandin Antagonists; Prostaglandins E; Rats; Rats, Inbred Strains | 1989 |
Activation of ras oncogenes in chemically transformed BALB/MK-2 mouse keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcium Chloride; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Gene Expression Regulation, Neoplastic; Genes, ras; Keratinocytes; Methylcholanthrene; Methylnitronitrosoguanidine; Mice; Mice, Nude; Nucleic Acid Hybridization; Oncogene Protein p21(ras); Transfection | 1989 |
Malignant conversion of UV radiation and chemically induced mouse skin benign tumors by free-radical-generating compounds.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Amidines; Animals; Benzoyl Peroxide; Carcinogens; Cell Transformation, Neoplastic; Female; Free Radicals; Mice; Mice, Hairless; Mice, Inbred Strains; Neoplasms, Radiation-Induced; Papilloma; Peroxides; Skin; Skin Diseases; Skin Neoplasms; tert-Butylhydroperoxide; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1989 |
Consistent oncogene methylation changes in epithelial cells chemically transformed in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Benzo(a)pyrene; Blotting, Southern; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Epithelial Cells; Epithelium; Genes, ras; Male; Methylation; Proto-Oncogenes; Rats; Rats, Inbred F344; Restriction Mapping; Tetradecanoylphorbol Acetate; Trachea | 1989 |
Detection of transforming growth factor-alpha messenger RNA in normal and chemically transformed hamster oral epithelium by in situ hybridization.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma in Situ; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cricetinae; Gene Expression Regulation, Neoplastic; Mouth Mucosa; Nucleic Acid Hybridization; RNA, Messenger; RNA, Neoplasm; Time Factors; Transforming Growth Factors | 1989 |
Absence of mutations in codon 61 of the Ha-ras oncogene in epithelial cells transformed in vitro by 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Cell Line, Transformed; Cell Transformation, Neoplastic; Codon; Epithelium; Exons; Genes, ras; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Rats; Respiratory System; RNA, Messenger | 1989 |
Light and electron microscopic study of hamster cheek pouch treated with 9,10 dimethyl 1,2 benzanthracene and retinoic acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Papillary; Carcinoma, Squamous Cell; Cell Nucleus; Cell Transformation, Neoplastic; Cheek; Cricetinae; Cytoplasm; Epithelium; Female; Male; Mesocricetus; Microscopy, Electron; Mouth Mucosa; Mouth Neoplasms; Neoplasm Invasiveness; Tretinoin | 1989 |
Experimental study on the treatment of oral precancerous lesion--short and long term effect of tablet Anticancer II.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Cell Transformation, Neoplastic; Cricetinae; DNA, Neoplasm; Drugs, Chinese Herbal; Female; Image Processing, Computer-Assisted; Male; Mesocricetus; Mouth Neoplasms; Precancerous Conditions; Random Allocation; Time Factors | 1989 |
Malignant transformation of a cloned, nontumorigenic mouse epidermal keratinocyte cell line, MSK-C3H-NU, by 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; Chromosomes; Clone Cells; Keratins; Mice; Mice, Inbred C3H; Mice, Nude; Skin Neoplasms | 1985 |
Immunological identity of a 60 kd oncofetal protein induced in rats by chemical carcinogens and released by transformed cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies; Antigens, Neoplasm; Carcinogens; Cell Transformation, Neoplastic; Epitopes; Female; Immunosorbent Techniques; Liver Neoplasms, Experimental; Mammary Neoplasms, Experimental; Neoplasm Transplantation; Rats; Rats, Inbred BUF; Rats, Inbred Strains | 1985 |
beta-Carotene reduces sister chromatid exchanges induced by chemical carcinogens in mouse mammary cells in organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Carcinogens; Carotenoids; Cell Transformation, Neoplastic; Diethylnitrosamine; Female; Fenretinide; Mammary Glands, Animal; Methylnitrosourea; Mice; Organ Culture Techniques; Retinoids; Sister Chromatid Exchange; Tretinoin | 1985 |
Mammary tumors in feral mice lacking MuMTV DNA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Cell Transformation, Neoplastic; Collodion; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Genes, Viral; Liver; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Muridae; Paper; Spleen | 1985 |
Mammary preneoplasia and tumorigenesis in the BALB/c mouse: structure and modification of mouse mammary tumor virus DNA sequences.
Topics: 5-Methylcytosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cytosine; DNA Restriction Enzymes; DNA, Viral; Female; Genes, Viral; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methylation; Mice; Mice, Inbred BALB C; Precancerous Conditions; Recombination, Genetic; Virus Replication | 1987 |
Inhibition of oral carcinogenesis by a protease inhibitor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cricetinae; Diethyl Pyrocarbonate; Iodoacetamide; Isoflurophate; Male; Mesocricetus; Mouth Neoplasms; Peptide Hydrolases; Trypsin Inhibitor, Bowman-Birk Soybean; Trypsin Inhibitors | 1986 |
Potential carcinogenicity of aza-aromatic hydrocarbons: azabenz(a)anthracenes.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Aza Compounds; Benz(a)Anthracenes; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Rats | 1986 |
Identification of environmental carcinogens utilizing T-cell mediated immunity.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Asbestos; Carcinogens, Environmental; Cell Transformation, Neoplastic; Cytotoxicity, Immunologic; Dimethylhydrazines; Dose-Response Relationship, Radiation; Environmental Exposure; Humans; Hydrocarbons, Halogenated; Immunity, Cellular; Intestinal Neoplasms; Mathematics; Neoplasms; Neoplasms, Radiation-Induced; Radioisotopes; Risk; T-Lymphocytes | 1986 |
Induction of UDP-glucuronyltransferase and arylhydrocarbon hydroxylase activity in mouse skin and in normal and transformed skin cells in culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aroclors; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Cells, Cultured; Chlorodiphenyl (54% Chlorine); Enzyme Induction; Female; Glucuronosyltransferase; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Skin; Skin Neoplasms | 1986 |
Modification by antioxidants and p,p'-diaminodiphenylmethane of 7,12-dimethylbenz[a]anthracene-induced carcinogenesis of the mammary gland and ear duct in CD rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Ascorbic Acid; Bisacodyl; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Transformation, Neoplastic; Cresols; Diet; Ear Neoplasms; Ethoxyquin; Female; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Vitamin E | 1986 |
Analysis of the interlaboratory and intralaboratory reproducibility of the enhancement of simian adenovirus SA7 transformation of Syrian hamster embryo cells by model carcinogenic and noncarcinogenic compounds.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Adenoviridae; Adenoviruses, Simian; Animals; Benzo(a)pyrene; Carcinogens; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Chromates; Cocarcinogenesis; Cricetinae; Diethylnitrosamine; Dose-Response Relationship, Drug; Embryo, Mammalian; Lead; Mesocricetus; Methylnitronitrosoguanidine | 1986 |
Retinoic acid enhancement of an early step in the transformation of mouse epidermal cells in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Dose-Response Relationship, Drug; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Effects of 12-O-tetradecanoylphorbol-13-acetate on carcinogen-induced mouse mammary lesions in organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Drug Synergism; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Tetradecanoylphorbol Acetate | 1986 |
Characterization of human IMR-90 fibroblasts as a model system for the study of chemical carcinogenesis in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aryl Hydrocarbon Hydroxylases; Cell Line; Cell Transformation, Neoplastic; DNA Replication; Fibroblasts; Humans; Mutagenicity Tests | 1986 |
Protective effects of beta-carotene against psoralen phototoxicity: relevance to protection against carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Carotenoids; Cell Transformation, Neoplastic; DNA; Furocoumarins; Humans; Neoplasms; Skin; Ultraviolet Rays; Vegetables | 1986 |
Inhibitory effects of the pineal hormone melatonin and underfeeding during the promotional phase of 7,12-dimethylbenzanthracene-(DMBA)-induced mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Cell Transformation, Neoplastic; Female; Food Deprivation; Mammary Neoplasms, Experimental; Melatonin; Prolactin; Rats; Rats, Inbred Strains | 1986 |
[Activation of oncogenes by chemical modification with carcinogens].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; DNA; Liver Neoplasms, Experimental; Mice; Mutation; Neoplasms, Experimental; Oncogenes; Papilloma; Proto-Oncogenes; Rats; Skin Neoplasms | 1986 |
In vitro transformation of mouse mammary epithelial cells grown serum-free inside collagen gels.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blood Physiological Phenomena; Cell Transformation, Neoplastic; Cells, Cultured; Collagen; Epithelium; Female; Gels; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C | 1987 |
Specific activation of the cellular Harvey-ras oncogene in dimethylbenzanthracene-induced mouse mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Mutation; Oncogenes; Polymorphism, Genetic | 1986 |
Sequential appearance of anchorage independence, uncontrolled nuclear division and tumorigenicity in 7,12-dimethylbenz(a)anthracene-exposed rat tracheal epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Adhesion; Cell Division; Cell Nucleus; Cell Transformation, Neoplastic; Cytochalasin B; Epithelial Cells; Neoplasms, Experimental; Rats; Time Factors; Trachea | 1987 |
Morphological characterization of cellular and extracellular components of 7,12 dimethylbenz[a]anthracene induced melanoma tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cricetinae; Male; Melanoma; Mesocricetus; Microscopy, Electron; Skin Neoplasms | 1987 |
Variability in response pattern of DMBA induced mammary tumors of Wistar rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Female; Mammary Neoplasms, Experimental; Neoplasm Regression, Spontaneous; Rats; Rats, Inbred Strains; Time Factors | 1987 |
Expression of c-erbB proto-oncogene during dimethylbenzanthracene-induced tumorigenesis in hamster cheek pouch.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cell Transformation, Neoplastic; Cricetinae; Gene Expression Regulation; Genes; Mouth Neoplasms; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; RNA, Messenger | 1987 |
H-ras activation in benign and self-regressing skin tumors (keratoacanthomas) in both humans and an animal model system.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Disease Models, Animal; Gene Expression Regulation; Genes, ras; Humans; Keratoacanthoma; Male; Middle Aged; Rabbits; Skin Diseases | 1988 |
Expression of phenotypical changes by human breast epithelial cells treated with carcinogens in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adolescent; Adult; Animals; Antigens, Neoplasm; Breast; Cell Transformation, Neoplastic; Cells, Cultured; Cytochalasin B; Epithelium; Female; Humans; Karyotyping; Lectins; Male; Membrane Glycoproteins; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Mucin-1; Oncogenes; Phenotype | 1988 |
Tumor induction through varying lengths of carcinogen exposure.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Mesocricetus; Mouth Neoplasms; Papilloma; Time Factors | 1986 |
Resistance to serum-induced terminal differentiation in normal human tracheobronchial epithelial cells after in vivo exposure to 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blood Physiological Phenomena; Bronchi; Cell Transformation, Neoplastic; Epithelium; Humans; Phenotype; Rats; Rats, Inbred F344; Trachea; Transplantation, Heterologous | 1988 |
Nuclear phenotypical changes of human breast epithelial cells treated with carcinogens.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Adult; Breast; Cell Nucleolus; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; Chromatin; Female; Humans; Methylnitrosourea; Nitroquinolines; Phenotype | 1987 |
Early neoplastic commitment of hamster buccal pouch epithelium exposed biweekly to 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cheek; Cricetinae; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Time Factors; Transfection | 1988 |
Activated Ki-ras genes in bladder epithelial cell lines transformed by treatment of primary mouse bladder explant cultures with 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Southern; Cell Line, Transformed; Cell Transformation, Neoplastic; Cricetinae; DNA; DNA Mutational Analysis; DNA-Directed DNA Polymerase; Gene Expression Regulation; Mice; Oligonucleotide Probes; Oncogenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Transfection; Urinary Bladder Neoplasms | 1988 |
Covalent binding of 7,12-dimethylbenz(a)anthracene and 10-fluoro-7,12-dimethylbenz(a)anthracene to mouse epidermal DNA and its relationship to tumor-initiating activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Chromatography, High Pressure Liquid; DNA; Epidermis; Mice; Skin; Structure-Activity Relationship | 1985 |
A quantitative ultrastructural study of alterations in the area of the basal cell-stromal interface during experimental oral carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Basement Membrane; Cell Membrane; Cell Transformation, Neoplastic; Connective Tissue; Cricetinae; Epithelium; Hyperplasia; Male; Mesocricetus; Microscopy, Electron; Mouth Mucosa; Mouth Neoplasms | 1985 |
Two-stage tumor promotion in mouse skin: an alternative interpretation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Croton Oil; Fluocinolone Acetonide; Mice; Mice, Inbred Strains; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1985 |
Stereoscopic back-scattered electron imaging of silver-stained proteins in nucleoli.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Cell Nucleolus; Cell Transformation, Neoplastic; Cells, Cultured; Nucleolus Organizer Region; Silver | 1985 |
Iron exclusion by proliferative foci and neoplastic lesions induced by 7,12-dimethylbenz(a)anthracene in the rat adrenal cortex.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Animals; Cell Transformation, Neoplastic; Female; Histocytochemistry; Iron; Male; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1985 |
Partial inversion of the initiation-promotion sequence of multistage tumorigenesis in the skin of NMRI mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Diterpenes; Female; Mice; Phorbol Esters; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Effect of mouse interferon on chemical carcinogenesis in normal rat kidney cells infected with Moloney murine leukemia virus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Interferon Type I; Kidney; Methylcholanthrene; Mice; Moloney murine leukemia virus; Rats | 1985 |
An ultrastructural morphometric study of cellular and nuclear volume alterations during experimental oral carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Nucleus; Cell Transformation, Neoplastic; Cheek; Cricetinae; Cytoplasm; Epithelium; Male; Mesocricetus; Microscopy, Electron; Mouth Mucosa; Mouth Neoplasms | 1985 |
On the possibility of in vitro transformation of human peripheral blood lymphocytes by chemical carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benz(a)Anthracenes; Carcinogens; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Humans; In Vitro Techniques; Lectins; Lymphocytes; Models, Biological; Protein Conformation | 1974 |