9,10-dimethyl-1,2-benzanthracene has been researched along with Animal Mammary Carcinoma in 108 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (5.56) | 18.7374 |
| 1990's | 14 (12.96) | 18.2507 |
| 2000's | 56 (51.85) | 29.6817 |
| 2010's | 29 (26.85) | 24.3611 |
| 2020's | 3 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Bessonneau, V; Chen, Z; Dang, NM; Gurdogan, H; Hillegass, M; Joshi, S; Kanefsky, J; Rahulkannan, V; Rudel, R; Russo, J; Santucci-Pereira, J; Schneider, SS; Ser-Dolansky, J; Su, Y | 1 |
| Bartlett, AP; Harman, RM; Jerry, DJ; Majhi, PD; Miller, JL; Van de Walle, GR | 1 |
| Chen, H; Sun, J; Yang, Z; Zhang, J; Zhou, B | 1 |
| Doll, MA; Hein, DW; Samuelson, DJ; Sanders, MA; States, JC; Stepp, MW | 1 |
| Berton, TR; Conti, CJ; Fuchs-Young, R; Hursting, SD; Lambertz, IU; Luo, L; Schwartz, SL | 1 |
| Dong, W; Liu, HN; Shang, GB; Tang, XL; Xu, GL; Zhu, WF | 1 |
| Orhan, C; Ozercan, IH; Sahin, K; Sahin, N; Tuzcu, M; Yabas, M | 1 |
| Samuelson, DJ; Sanders, J | 1 |
| Elshimali, Y; Kim, J; Sarkissyan, M; Vadgama, JV; Wu, Y | 1 |
| Castaño, JP; Córdoba-Chacón, J; Gahete, MD; Kineman, RD; Lantvit, DD; López-Miranda, J; Luque, RM; Ortega-Salas, R; Pérez-Jiménez, F; Sanchez-Sanchez, R; Swanson, SM | 1 |
| Escrich, E; Escrich, R; Manzanares, MÁ; Moral, R; Solanas, M; Vela, E | 1 |
| Chen, C; Ge, GZ; He, BL; Jiao, JL; Lv, LB; Wang, CY; Xia, HJ; Zhang, HL; Zhang, YX | 1 |
| Apostoli, AJ; Di Lena, MA; Nicol, CJ; Peterson, NT; Roche, JM; Rubino, RE; Schneider, MM; SenGupta, SK | 1 |
| Badger, TM; Hakkak, R; Korourian, S; Ronis, MJ | 1 |
| Escrich, E; Escrich, R; Moral, R; Rodríguez-Miguel, C; Solanas, M; Vela, E | 1 |
| Jamdade, VS; Kumar, P; Lahkar, M; Mundhe, NA; Tadla, V | 1 |
| Álvarez-Benito, M; Castaño, JP; de Lecea, L; Gahete, MD; L-López, F; López-Miranda, J; Luque, RM; Ortega-Salas, R; Pozo-Salas, AI; Sánchez-Sánchez, R; Villa-Osaba, A | 1 |
| Agnihotri, N; Bhatnagar, A; Negi, AK | 1 |
| Feith, DJ; Gestl, SA; Gunther, EJ; Hoke, A; Keller, RR; Lu, AQ | 1 |
| Ganaie, IA; Jain, SK; Naqvi, SH; Wajid, S | 1 |
| Hoshi, K; Qin, LQ; Tezuka, H; Wang, PY; Xu, JY | 1 |
| Kaufmann, Y; Klimberg, VS; Luo, S; Todorova, VK | 1 |
| Escrich, E; Escrich, R; Garcia, G; Grau, L; Moral, R; Solanas, M; Vela, E | 1 |
| Al mslmani, MA; Moselhy, SS | 1 |
| Chen, BQ; Dong, HW; Liu, JR; Liu, RH; Zhao, P | 1 |
| Benakanakere, I; Besch-Williford, C; Ellersieck, MR; Hyder, SM | 1 |
| Chen, HF; Hsieh, PH; Lo, CY; Su, HM | 1 |
| Carpenter, M; Eltoum, I; Jenkins, S; Lamartiniere, CA; Raghuraman, N; Russo, J | 1 |
| Fan, HY; Peng, JH; Zhang, F; Zhang, HX | 1 |
| Cai, L; Dong, JZ; Li, FJ; Mi, MT; Peng, JH; Xue, RL; Zhang, HX; Zhao, Y; Zhu, JD | 1 |
| Balakrishnan, S; Baskaran, N; Manoharan, S; Pugalendhi, P | 1 |
| Arlt, VM; Fenton, SE; Gavin, HM; Lawrence, BP; Medina, D; Vorderstrasse, BA; Wang, T | 1 |
| Becks, L; Broadway, M; Burson, H; Christophe, C; Itoh, K; Kleiner-Hancock, HE; Mathis, M; McLarty, J; Orchard, E; Prince, M; Pruitt, K; Shi, R; Yamamoto, M; Zhang, S | 1 |
| Allan, AL; Barr, K; Laird, DW; Plante, I; Stewart, MK | 1 |
| Choi, EJ; Kim, GH | 1 |
| Benakanakere, I; Besch-Williford, C; Ellersieck, MR; Hyder, SM; López Pérez, FR; Mafuvadze, B | 1 |
| Al-Malki, AL; Moselhy, SS; Refai, MY | 1 |
| Brenner, DJ; Shuryak, I; Ullrich, RL | 1 |
| Carlson, BA; Green, JE; Hatfield, DL; Hoeneroff, MJ; Hudson, TS; Muller, WJ; Sordillo, L; Young, HA | 1 |
| Bobrowska-Korczak, B; Skrajnowska, D; Tokarz, A | 1 |
| Akila, R; Anburajan, M; Angeline Kirubha, SP; Raj, B; Sharath, D; Venkataraman, B | 1 |
| Hirose, M; Imai, T; Matsui, T; Mitsumori, K; Onodera, H; Takagi, H; Takizawa, T; Ueda, M; Yasuhara, K | 1 |
| Colomer, R; Costa, I; Escrich, E; Hurtado, A; Menéndez, JA; Moral, R; Solanas, M | 1 |
| Ammälä, J; Collan, YU; Eckerman, C; Huovinen, R; Lehtilä, R; Mäkelä, SI; Saarinen, NM; Santti, RS; Sjöholm, R; Valentín-Blasini, L; Wärri, A | 1 |
| Chan, FL; Chen, ZY; Cheung, SY; Choi, HL; Huang, Y; James, AE | 1 |
| Constantinou, AI; Husband, A; Mehta, R | 1 |
| Chan, FL; Chen, S; Cheng, HK; Cheung, SY; Choi, HL; Huang, Y; Yuen, MT | 1 |
| De Jonage-Canonico, MB; Kerdelhué, B; Lenoir, V; Martin, A; Scholler, R | 1 |
| CURRIE, AR; HELFENSTEIN, JE; YOUNG, S | 1 |
| BATHER, R; CUSHING, J | 1 |
| HELFENSTEIN, JE; YOUNG, S | 1 |
| DANIEL, PM; PRICHARD, MM | 1 |
| BAKER, RA; HELFENSTEIN, JE; YOUNG, S | 1 |
| MCCORMICK, GM; MOON, RC | 1 |
| Amin, S; Boyiri, T; Das, A; Desai, D; El-Bayoumy, K; Pittman, B; Sinha, R | 1 |
| Beg, ZH; Iqbal, J; Minhajuddin, M | 1 |
| Babb, K; Hawk, R; Johnson, AT; Kaufmann, Y; Klimberg, VS; Luo, S | 1 |
| Medina, D | 1 |
| Singh, M; Thompson, HJ | 1 |
| Fukamachi, K; Han, BS; Kim, CK; Matsuda, E; Matsuoka, Y; Takasuka, N; Tsuda, H; Yamasaki, T | 1 |
| Cho-Chung, YS; Nesterova, MV | 2 |
| Escrich, E; Haro, D; Manzanares, EM; Moral, R; Solanas, M | 1 |
| Okuyama, N; Sasaki, K; Umemura, S; Yumita, N | 1 |
| Ben-Hur, H; Elhayany, A; Kossoy, G; Schneider, DF; Zusman, I | 1 |
| Chen, B; Liu, J; Liu, RH | 1 |
| Fong, LY; Grubbs, CJ; Guler, G; Han, SY; Huebner, K; Iliopoulos, D; Lubet, RA | 1 |
| de Jonage-Canonico, MB; Kerdelhué, B; Lenoir, V; Martin, A; Perrin, MH; Scholler, R | 1 |
| Alakavuklar, M; Canda, T; Cehreli, R; Demirkan, B; Harmancioglu, O; Kocdor, H; Kocdor, MA; Resmi, H; Sis, B; Yilmaz, O | 1 |
| Alonso-González, C; Cos, S; González, A; Güezmes, A; Martínez-Campa, C; Mediavilla, MD; Sánchez-Barceló, EJ | 1 |
| Hirose, M; Imazawa, T; Kitamura, Y; Matsumoto, W; Nishikawa, A; Okazaki, K; Umemura, T; Yamagishi, M | 1 |
| Chen, WY; Holle, E; Jacquemart, IC; Langenheim, JF; Tomblyn, S | 1 |
| Cho, YM; Hasumura, M; Hirose, M; Imai, T | 1 |
| Demicco, EG; Kavanagh, KT; Landesman-Bollag, E; Romieu-Mourez, R; Seldin, DC; Shin, SR; Sonenshein, GE; Wang, X | 1 |
| Lai, H; Singh, NP | 1 |
| Brooks, SC; Chen, J; Lu, S; Santner, SJ; Shen, K; Wang, Y; Wang, YA | 1 |
| Baffi, MO; Chen, DT; Crowley, MR; Frost, A; Nicola, T; Serra, R | 1 |
| Coppieters, W; Farnir, F; Georges, M; Laes, JF; Quan, X; Rivière, M; Russo, J; Stieber, D; Szpirer, C; Szpirer, J; Wedekind, D | 1 |
| de Assis, S; Hilakivi-Clarke, L; Khan, G | 1 |
| Das, SK; Mukherjee, S; Mukhopadhyay, S | 1 |
| Bringel, J; Grenet, O; Harleman, JH; Marxfeld, H; Staedtler, F | 1 |
| Blanco-Aparicio, C; Carnero, A; Leal, JF; Pequeño, B; Pérez-Gallego, L; Renner, O | 1 |
| Fuchs, G; Hakkak, R; Holley, AW; Jo, CH; Kieber-Emmons, T; Korourian, S; MacLeod, S; Shaaf, S; Simpson, P | 1 |
| Akhter, S; Ambrus, CM; Ambrus, JL; Islam, A; Lillie, MA; Pickren, JW | 1 |
| Belguise, K; Guo, S; Rogers, AE; Seldin, DC; Sherr, DH; Sonenshein, GE; Yang, S | 1 |
| Hawthorne, M; Mehta, RG; Peng, X; St-Arnaud, R; Vaishnav, A | 1 |
| Bunce, OR; Gunnett, CA; Harris, SR; Hartle, DK; Mehta, RS | 1 |
| Dove, WF; Gould, MN; Haag, JD; Lindstrom, MJ; Mattes, EM; Moser, AR | 1 |
| Crean, DH; Dougherty, TJ; Liebow, C; Mang, TS; McGinnis, C; Nseyo, UO | 1 |
| Brodie, A; Lu, Q; Nakamura, J; Savinov, A | 1 |
| Katdare, M; Newmark, H; Osborne, MP; Singhal, H; Telang, NT | 1 |
| Bartorelli, A; Bussolati, B; Bussolati, G; Di Carlo, F; Racca, S | 1 |
| Bechtel, DH; Chen, JJ; Jackson, CD; Poirier, LA; Weis, C | 1 |
| Nickerson, T; Pollak, M; Zhang, J | 1 |
| Appelt, LC; Reicks, MM | 1 |
| Hafer, LJ; Rogers, AE; Sullivan, LM | 1 |
| Ishikawa, H; Itoh, J; Kawai, K; Kobayashi, H; Ogawa, K; Osamura, RY; Serizawa, A; Takeshita, T; Yasumura, K | 1 |
| Abou-Issa, H; Alshafie, GA; Harris, RE; Seibert, K | 1 |
| Ben-Hur, H; Kossoy, G; Kossoy, N; Zusman, I | 1 |
| Huang, RY; Ip, MM | 1 |
| Cho, MY; Jang, TJ; Kim, JR; Park, JH | 1 |
| Hafer, LJ; Kavanagh, KT; Kim, DW; Mann, KK; Rogers, AE; Sherr, DH; Sonenshein, GE | 1 |
| Daeuble, JF; Dou, J; Grieco, PA; Kinghorn, AD; Mata-Greenwood, E; McChesney, JD; Mehta, RG; Pezzuto, JM | 1 |
| Bombardelli, E; Cantelmo, F; Ferrandina, G; Fruscella, E; Gallo, D; Giacomelli, S; Mancuso, S; Morazzoni, P; Riva, A; Scambia, G; Zannoni, GF | 1 |
| Gottlieb, C; Greer, S; Marion, HS; Santos, O; Schwade, J | 1 |
| Thompson, LU; Zhang, L | 1 |
| Hirose, M; Ito, N; Kamano, K; Masuda, A; Okuyama, H | 1 |
| Cantell, K; Kangas, L; Schellekens, H | 1 |
3 review(s) available for 9,10-dimethyl-1,2-benzanthracene and Animal Mammary Carcinoma
| Article | Year |
|---|---|
Induced mammary cancer in rat models: pathogenesis, genetics, and relevance to female breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Estrogens; Female; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Quantitative Trait Loci; Rats; Rats, Sprague-Dawley | 2022 |
Rat models of premalignant breast disease.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Disease Models, Animal; Mammary Neoplasms, Animal; Methylnitrosourea; Precancerous Conditions; Rats | 2000 |
Chemoprevention with protein kinase A RIalpha antisense in DMBA-mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; DNA Repair; Down-Regulation; Humans; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mice; Oligonucleotides, Antisense; Transcription Factors | 2005 |
105 other study(ies) available for 9,10-dimethyl-1,2-benzanthracene and Animal Mammary Carcinoma
| Article | Year |
|---|---|
Effects of Pubertal Exposure to Butyl Benzyl Phthalate, Perfluorooctanoic Acid, and Zeranol on Mammary Gland Development and Tumorigenesis in Rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Caprylates; Carcinogenesis; Cell Transformation, Neoplastic; Endocrine Disruptors; Female; Fluorocarbons; Hormones; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Phthalic Acids; Rats; Rats, Sprague-Dawley; Zeranol | 2022 |
Betulin ameliorates 7,12-dimethylbenz(a)anthracene-induced rat mammary cancer by modulating MAPK and AhR/Nrf-2 signaling pathway.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mammary Neoplasms, Animal; MAP Kinase Signaling System; Neoplasm Proteins; NF-E2-Related Factor 2; Rats; Receptors, Aryl Hydrocarbon; Triterpenes | 2021 |
Congenic rats with higher arylamine N-acetyltransferase 2 activity exhibit greater carcinogen-induced mammary tumor susceptibility independent of carcinogen metabolism.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arylamine N-Acetyltransferase; Carcinogens; Disease Susceptibility; Female; Inactivation, Metabolic; Mammary Neoplasms, Animal; Rats; Rats, Inbred F344; Rats, Inbred WKY | 2017 |
Early Exposure to a High Fat/High Sugar Diet Increases the Mammary Stem Cell Compartment and Mammary Tumor Risk in Female Mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adiponectin; Animals; Body Weight; Carcinogenesis; Diet, Fat-Restricted; Diet, High-Fat; Dietary Sugars; Feeding Behavior; Female; Insulin Resistance; Insulin-Like Growth Factor I; Lactation; Leptin; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Maternal Exposure; Mice; Mice, Inbred SENCAR; Obesity; Risk Factors; Stem Cells; Time Factors | 2017 |
Dampness-Heat Accelerates DMBA-Induced Mammary Tumors in Rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Female; Hot Temperature; Interleukin-1beta; Mammary Neoplasms, Animal; Matrix Metalloproteinase 9; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-1; Tumor Burden; Tumor Necrosis Factor-alpha | 2018 |
LFM-A13, a potent inhibitor of polo-like kinase, inhibits breast carcinogenesis by suppressing proliferation activity and inducing apoptosis in breast tumors of mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amides; Animals; Apoptosis; Carcinogenesis; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cell Survival; Female; Humans; Mammary Neoplasms, Animal; Mice, Inbred BALB C; Nitriles; Paclitaxel; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Rats; Survival Analysis | 2018 |
Significant overlap between human genome-wide association-study nominated breast cancer risk alleles and rat mammary cancer susceptibility loci.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Breast Neoplasms; Chromosome Mapping; Estradiol; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Genomics; Humans; Mammary Neoplasms, Animal; Polymorphism, Single Nucleotide; Rats; Rats, Inbred WF; Rats, Inbred WKY; Rats, Wistar; Risk; Selenoproteins | 2014 |
Activation of Akt1 accelerates carcinogen-induced tumorigenesis in mammary gland of virgin and post-lactating transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Disease Models, Animal; Estrogen Receptor alpha; Female; Humans; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mice; Mice, Transgenic; Proto-Oncogene Proteins c-akt; Signal Transduction | 2014 |
Elevated GH/IGF-I promotes mammary tumors in high-fat, but not low-fat, fed mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abnormalities, Multiple; Animals; Breast Neoplasms; Diet, Fat-Restricted; Diet, High-Fat; Female; Growth Disorders; Growth Hormone; Humans; Insulin Resistance; Insulin-Like Growth Factor I; Mammary Neoplasms, Animal; Mice; Obesity | 2014 |
Ontogeny of the major xenobiotic-metabolizing enzymes expression and the dietary lipids modulatory effect in the rat dimethylbenz(a)anthracene-induced breast cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Aryl Hydrocarbon Hydroxylases; Carcinogens; Corn Oil; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione S-Transferase pi; Mammary Neoplasms, Animal; NAD(P)H Dehydrogenase (Quinone); Neoplasm Proteins; NF-E2-Related Factor 2; Olive Oil; Plant Oils; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Xenobiotics | 2014 |
PTEN/PIK3CA genes are frequently mutated in spontaneous and medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced mammary tumours of tree shrews.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Ductal, Breast; Carcinoma, Papillary; Disease Models, Animal; Estrogens; Female; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Medroxyprogesterone Acetate; Mutation; Papilloma, Intraductal; Phosphatidylinositol 3-Kinase; Progesterone; PTEN Phosphohydrolase; Random Allocation; Receptors, Estrogen; Receptors, Progesterone; Tupaiidae | 2014 |
Opposing roles for mammary epithelial-specific PPARγ signaling and activation during breast tumour progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; BRCA1 Protein; Cytokines; Disease Progression; Epithelial Cells; Female; Gene Deletion; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice, Knockout; Models, Biological; Organ Specificity; PPAR gamma; Signal Transduction; Tumor Burden | 2015 |
Whey Protein Hydrolysate but not Whole Whey Protein Protects Against 7,12-Dimethylbenz(a)anthracene-Induced Mammary Tumors in Rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Caseins; Diet; Disease Models, Animal; Female; Mammary Neoplasms, Animal; Pregnancy; Protective Agents; Protein Hydrolysates; Rats; Rats, Sprague-Dawley; Whey Proteins | 2015 |
The Role of Dietary Extra Virgin Olive Oil and Corn Oil on the Alteration of Epigenetic Patterns in the Rat DMBA-Induced Breast Cancer Model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Corn Oil; Diet, High-Fat; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histones; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Olive Oil; Promoter Regions, Genetic; Protein Processing, Post-Translational; Rats, Sprague-Dawley; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-3; Tumor Suppressor Proteins | 2015 |
Raloxifene Inhibits NF-kB Pathway and Potentiates Anti-Tumour Activity of Cisplatin with Simultaneous Reduction in its Nephrotoxictiy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Cisplatin; Drug Synergism; Female; Inflammation; Kidney Diseases; Mammary Neoplasms, Animal; NF-kappa B; Raloxifene Hydrochloride; Rats; Rats, Wistar; Signal Transduction | 2016 |
Lack of cortistatin or somatostatin differentially influences DMBA-induced mammary gland tumorigenesis in mice in an obesity-dependent mode.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Female; Humans; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mice; Mice, Knockout; Mice, Obese; Neuropeptides; Somatostatin | 2016 |
Fish oil augments celecoxib mediated alteration in apoptotic pathway in the initiation phase of 7,12-dimethylbenz(α)anthracene-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; bcl-2-Associated X Protein; Carcinogenesis; Caspase 8; Celecoxib; Cell Separation; Cytochromes c; Epithelial Cells; Fas Ligand Protein; fas Receptor; Female; Fish Oils; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Membrane Potential, Mitochondrial; Rats, Wistar; Signal Transduction | 2016 |
Carcinogen-specific mutations in preferred Ras-Raf pathway oncogenes directed by strand bias.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogenesis; Carcinogens; Ethylnitrosourea; Female; Gene Expression Regulation, Neoplastic; Genotype; Humans; Mammary Neoplasms, Animal; Mice; Mutation; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); Wnt1 Protein | 2016 |
Reduced expression of SETD2 and SNX9 proteins in chemically induced mammary tumorigenesis in Wistar rats: a prognostic histological and proteomic study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Cell Proliferation; Female; Histone-Lysine N-Methyltransferase; Mammary Glands, Animal; Mammary Neoplasms, Animal; Proteomics; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Sorting Nexins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2017 |
Milk inhibits the regression of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in ovariectomized rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Estradiol; Female; Insulin-Like Growth Factor I; Mammary Neoplasms, Animal; Milk; Organ Size; Ovariectomy; Rats; Rats, Sprague-Dawley; Uterus | 2008 |
Glutamine affects glutathione recycling enzymes in a DMBA-induced breast cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Diet; Female; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutaminase; Glutamine; Glutathione; Intestinal Mucosa; Mammary Neoplasms, Animal; Pyroglutamate Hydrolase; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2008 |
High corn oil and high extra virgin olive oil diets have different effects on the expression of differentiation-related genes in experimental mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animal Feed; Animals; Blotting, Northern; Blotting, Western; Carcinogens; Caseins; Cell Differentiation; Corn Oil; Dietary Fats, Unsaturated; Female; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Animal; Olive Oil; Plant Oils; Rats; Rats, Sprague-Dawley; RNA-Binding Proteins; Transferrin | 2008 |
Chemopreventive effect of lycopene alone or with melatonin against the genesis of oxidative stress and mammary tumors induced by 7,12 dimethyl(a)benzanthracene in sprague dawely female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Carcinogens; Carotenoids; Female; Lycopene; Malondialdehyde; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Melatonin; Nitric Oxide; Oxidative Stress; Oxidoreductases; Rats; Rats, Sprague-Dawley | 2008 |
Fresh apples suppress mammary carcinogenesis and proliferative activity and induce apoptosis in mammary tumors of the Sprague-Dawley rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Cell Division; Female; Fruit; Malus; Mammary Neoplasms, Animal; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley | 2009 |
Regression of progestin-accelerated 7,12-dimethylbenz[a]anthracene-induced mammary tumors in Sprague-Dawley rats by p53 reactivation and induction of massive apoptosis: a pilot study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Apoptosis; Aza Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carcinogens; Drug Resistance, Neoplasm; Female; Mammary Neoplasms, Animal; Medroxyprogesterone Acetate; Mutation; Neovascularization, Pathologic; Osteonectin; Pilot Projects; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A | 2009 |
A maternal high-fat diet during pregnancy in rats results in a greater risk of carcinogen-induced mammary tumors in the female offspring than exposure to a high-fat diet in postnatal life.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Dietary Fats; Estradiol; Female; Lipids; Mammary Neoplasms, Animal; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Risk Factors | 2009 |
Oral exposure to bisphenol a increases dimethylbenzanthracene-induced mammary cancer in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzhydryl Compounds; Carcinogens; Female; Lactation; Mammary Glands, Animal; Mammary Neoplasms, Animal; Maternal Exposure; Phenols; Rats; Rats, Sprague-Dawley | 2009 |
Prepubertal octylphenol exposure up-regulate BRCA1 expression, down-regulate ERalpha expression and reduce rat mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; BRCA1 Protein; Down-Regulation; Estrogen Receptor alpha; Female; Genistein; Mammary Neoplasms, Animal; Phenols; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation | 2009 |
Prepubertal genistein exposure affects erbB2/Akt signal and reduces rat mammary tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Blotting, Western; Carcinogens; Female; Genistein; Glycoproteins; Immunoenzyme Techniques; Immunohistochemistry; Mammary Neoplasms, Animal; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sexual Maturation | 2010 |
Chemopreventive potential of ferulic acid in 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Anticarcinogenic Agents; Coumaric Acids; Female; Immunohistochemistry; Mammary Neoplasms, Animal; Rats; Rats, Sprague-Dawley | 2010 |
Aryl hydrocarbon receptor activation during pregnancy, and in adult nulliparous mice, delays the subsequent development of DMBA-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Ligands; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Precancerous Conditions; Pregnancy; Pregnancy, Animal; Receptors, Aryl Hydrocarbon | 2011 |
Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animal Feed; Animals; Coumarins; Cytosol; Disease Progression; Drug Design; Female; Genotype; Liver; Lymphoma; Mammary Neoplasms, Animal; Mice; Mice, Inbred ICR; Mice, Knockout; NF-E2-Related Factor 2 | 2010 |
Cx43 suppresses mammary tumor metastasis to the lung in a Cx43 mutant mouse model of human disease.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Connexin 43; Disease Models, Animal; Female; Humans; Lung Neoplasms; Mammary Neoplasms, Animal; Mice | 2011 |
Anti-/pro-apoptotic effects of hesperetin against 7,12-dimetylbenz(a)anthracene-induced alteration in animals.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Dose-Response Relationship, Drug; Down-Regulation; Drug Administration Schedule; Drug Evaluation, Preclinical; Female; Hesperidin; Mammary Neoplasms, Animal; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley; Up-Regulation | 2011 |
Apigenin prevents development of medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced mammary tumors in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apigenin; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Mammary Neoplasms, Animal; Medroxyprogesterone Acetate; Neovascularization, Pathologic; Placebos; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2011 |
Synergistic effect of lycopene and tocopherol against oxidative stress and mammary tumorigenesis induced by 7,12-dimethyl[a]benzanthracene in female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Body Weight; Carotenoids; Catalase; Drug Synergism; Female; Glutathione Peroxidase; Lycopene; Malondialdehyde; Mammary Neoplasms, Animal; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tocopherols | 2012 |
Radiation-induced carcinogenesis: mechanistically based differences between gamma-rays and neutrons, and interactions with DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Radiation; Female; Fibrocystic Breast Disease; Gamma Rays; Humans; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Models, Biological; Neoplasms, Radiation-Induced; Neutrons; Risk Factors | 2011 |
Selenoproteins reduce susceptibility to DMBA-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Progression; Female; Genotype; Mammary Neoplasms, Animal; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C57BL; Mice, Knockout; RNA, Transfer, Amino Acid-Specific; Selenocysteine; Selenoproteins | 2012 |
The effect of dietary zinc--and polyphenols intake on DMBA-induced mammary tumorigenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Carcinogens; Dietary Supplements; Female; Genistein; Mammary Neoplasms, Animal; Polyphenols; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Zinc | 2012 |
Evaluation of mammary cancer in 7,12-dimethylbenz(a)anthracene-induced Wister rats by asymmetrical temperature distribution analysis using thermography: a comparison with serum CEA levels and histopathology.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinoembryonic Antigen; Diagnosis, Computer-Assisted; Female; Mammary Neoplasms, Animal; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Thermography | 2012 |
Enhancing effects of beta-estradiol 3-benzoate but not methoxychlor on the promotion/progression stage of chemically-induced mammary carcinogenesis in ovariectomized rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Disease Progression; Estradiol; Female; Mammary Neoplasms, Animal; Methoxychlor; Ovary; Rats; Rats, Sprague-Dawley; Time Factors | 2002 |
Effects of a high olive oil diet on the clinical behavior and histopathological features of rat DMBA-induced mammary tumors compared with a high corn oil diet.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animal Feed; Animals; Body Weight; Carcinogens; Corn Oil; Fatty Acids; Female; Mammary Neoplasms, Animal; Olive Oil; Plant Oils; Rats; Rats, Sprague-Dawley; Time Factors | 2002 |
Enterolactone inhibits the growth of 7,12-dimethylbenz(a)anthracene-induced mammary carcinomas in the rat.
Topics: 4-Butyrolactone; 9,10-Dimethyl-1,2-benzanthracene; Animals; Aromatase Inhibitors; Carcinogens; Cell Division; Enzyme Inhibitors; Estrogens; Estrogens, Non-Steroidal; Female; Isoflavones; Lignans; Mammary Neoplasms, Animal; Models, Chemical; Organ Size; Phytoestrogens; Plant Preparations; Rats; Rats, Sprague-Dawley; Time Factors; Uterus | 2002 |
Spontaneous mammary tumors in aging Noble rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age of Onset; Animals; Carcinoma; Diethylstilbestrol; Drug Implants; Estradiol; Female; Fibroadenoma; Genetic Predisposition to Disease; Incidence; Male; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Metastasis; Neoplasm Transplantation; Ovariectomy; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Rodent Diseases; Species Specificity; Testosterone | 2003 |
Phenoxodiol, a novel isoflavone derivative, inhibits dimethylbenz[a]anthracene (DMBA)-induced mammary carcinogenesis in female Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzopyrans; Carcinogens; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Isoflavones; Mammary Neoplasms, Animal; Phenols; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 2003 |
An expression study of hormone receptors in spontaneously developed, carcinogen-induced and hormone-induced mammary tumors in female Noble rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinogens; DNA Primers; Female; Hormones; Immunohistochemistry; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Polymerase Chain Reaction; Rats; Rats, Inbred Strains; Receptors, Estrogen; Receptors, Progesterone; Receptors, Prolactin | 2003 |
Long term inhibition by estradiol or progesterone of melatonin secretion after administration of a mammary carcinogen, the dimethyl benz(a)anthracene, in Sprague-Dawley female rat; inhibitory effect of Melatonin on mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenergic beta-Agonists; Animals; Antioxidants; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Estradiol; Female; Isoproterenol; Mammary Neoplasms, Animal; Melatonin; Pineal Gland; Progesterone; Rats; Rats, Sprague-Dawley | 2003 |
Effect of thiouracil on the development of mammary tumours in rats induced with 9,10-dimethyl-1,2-benzanthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Breast Neoplasms; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Rats; Thiouracil | 1962 |
A virus resembling that of endemic pneumonia isolated from lymphosarcoma induced in Swiss mice by 9,10 dimethyl 1,2 benzanthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Avian Leukosis; Benz(a)Anthracenes; Breast Neoplasms; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice; Oncogenic Viruses; Pneumonia; Pneumonia, Viral | 1963 |
EFFECT OF 2-METHYL-1,2-BIS-(3-PYRIDYL)-1-PROPANONE (METYRAPONE) ON THE PRODUCTION OF MAMMARY TUMOURS INDUCED IN RATS BY ORAL FEEDING WITH DIMETHYLBENZANTHRACENE.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Carcinogens; Ketones; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Metyrapone; Mineralocorticoid Receptor Antagonists; Necrosis; Neoplasms, Experimental; Pharmacology; Rats; Research; Toxicology | 1963 |
THREE TYPES OF MAMMARY TUMOUR INDUCED IN RATS BY FEEDING WITH DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benz(a)Anthracenes; Castration; Female; Humans; Hypophysectomy; Lactation; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Neoplasms; Ovary; Pathology; Rats; Research | 1964 |
RELATIONSHIP OF ADRENOCORTICAL INSUFFICIENCY TO SPONTANEOUS REGRESSION IN MAMMARY TUMOURS INDUCED IN RATS BY ORAL ADMINISTRATION OF DIMETHYLBENZANTHRACENE.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Adrenal Insufficiency; Animals; Benz(a)Anthracenes; Cortisone; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Neoplasm Regression, Spontaneous; Pharmacology; Physiology; Rats; Research | 1964 |
EFFECT OF PREGNANCY AND LACTATION ON GROWTH OF MAMMARY TUMOURS INDUCED BY 7,12-DIMETHLBENZ(A) ANTHRACENE (DMBA).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Animals; Anthracenes; Benz(a)Anthracenes; Breast Feeding; Carcinogens; Female; Humans; Lactation; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Pregnancy; Pregnancy Complications; Pregnancy, Animal; Rats; Research | 1965 |
Comparative action of 1,4-phenylenebis(methylene)selenocyanate and its metabolites against 7,12-dimethylbenz[a]anthracene-DNA adduct formation in the rat and cell proliferation in rat mammary tumor cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Anticarcinogenic Agents; Carcinogens; Cell Division; DNA Adducts; DNA Damage; Female; Mammary Neoplasms, Animal; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Tumor Cells, Cultured | 2003 |
Suppression of 7,12-dimethylbenz[alpha]anthracene-induced carcinogenesis and hypercholesterolaemia in rats by tocotrienol-rich fraction isolated from rice bran oil.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acyl Coenzyme A; Administration, Oral; Alkaline Phosphatase; Animals; Antioxidants; Carcinogens; Cell Transformation, Neoplastic; Cholesterol; Female; Glutathione Transferase; Hypercholesterolemia; Liver; Mammary Neoplasms, Animal; Plant Oils; Rats; Rats, Sprague-Dawley; Rice Bran Oil; Tocotrienols | 2003 |
Gut glutathione metabolism and changes with 7,12-DMBA and glutamine.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animal Nutritional Physiological Phenomena; Animals; Carcinogens; Female; Glutamine; Glutathione; Intestinal Mucosa; Intestines; Mammary Neoplasms, Animal; Rats; Rats, Sprague-Dawley | 2003 |
Breast cancer: the protective effect of pregnancy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Breast Neoplasms; Carcinogens; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Epithelial Cells; Female; Humans; Immunohistochemistry; Mammary Glands, Human; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Phenotype; Pregnancy; Rats; Time Factors; Tumor Suppressor Protein p53 | 2004 |
Possible enhancing effects of atrazine and nonylphenol on 7,12-dimethylbenz[a]anthracene-induced mammary tumor development in human c-Ha-ras proto-oncogene transgenic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animal Feed; Animals; Animals, Genetically Modified; Atrazine; Biological Assay; Carcinogens; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Endocrine System; Female; Genes, ras; Genetic Predisposition to Disease; Herbicides; Humans; Male; Mammary Neoplasms, Animal; Phenols; Proto-Oncogene Mas; Rats; Risk Assessment | 2004 |
Antisense protein kinase A RIalpha inhibits 7,12-dimethylbenz(a)anthracene-induction of mammary cancer: blockade at the initial phase of carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Catalytic Domain; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; DNA Repair; Dose-Response Relationship, Drug; Down-Regulation; Ethanolamines; Female; Glutathione Transferase; Immunoprecipitation; Liver; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mice; NAD(P)H Dehydrogenase (Quinone); NADPH Dehydrogenase; Oligonucleotides, Antisense; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Time Factors; Transcription Factor AP-1; Transcription, Genetic | 2004 |
Influence of DMBA-induced mammary cancer on the liver CPT I, mit HMG-CoA synthase and PPARalpha mRNA expression in rats fed a low or high corn oil diet.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; Body Weight; Carcinogens; Carnitine O-Palmitoyltransferase; Coenzyme A Ligases; Fatty Acids; Female; Hydroxymethylglutaryl-CoA Synthase; Lipid Metabolism; Lipids; Liver; Mammary Neoplasms, Animal; Neoplasms; Oxygen; PPAR alpha; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger | 2004 |
Sonodynamic therapy on chemically induced mammary tumor: pharmacokinetics, tissue distribution and sonodynamically induced antitumor effect of porfimer sodium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Combined Modality Therapy; Dihematoporphyrin Ether; Female; Mammary Neoplasms, Animal; Rats; Rats, Sprague-Dawley; Tissue Distribution; Ultrasonic Therapy | 2004 |
Rat soluble tumor-associated antigens inhibit chemically-induced mammary tumorigenesis in syngeneic rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Carcinogens; Electrophoresis, Polyacrylamide Gel; Female; Humans; Immunotherapy, Active; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Time Factors | 2005 |
Apples prevent mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Carcinogens; Diet; Female; Fruit; Malus; Mammary Neoplasms, Animal; Rats; Rats, Sprague-Dawley | 2005 |
Hypermethylation patterns in the Fhit regulatory region are tissue specific.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acid Anhydride Hydrolases; Animals; Base Sequence; Carcinogens; DNA Methylation; DNA Primers; Female; Gene Expression Regulation; Genes, Regulator; Genes, Tumor Suppressor; Introns; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Proteins; Organ Specificity; Polymerase Chain Reaction; Rats | 2005 |
Preventive and curative effect of melatonin on mammary carcinogenesis induced by dimethylbenz[a]anthracene in the female Sprague-Dawley rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antioxidants; Carcinogens; Cell Transformation, Neoplastic; DNA Damage; Environmental Exposure; Female; Humans; Mammary Neoplasms, Animal; Melatonin; Rats; Rats, Sprague-Dawley; Risk Factors | 2005 |
Toxicity induced by the chemical carcinogen 7,12-dimethylbenz[a]anthracene and the protective effects of selenium in Wistar rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Kidney; Liver; Lung Neoplasms; Mammary Neoplasms, Animal; Rats; Rats, Wistar; Selenium | 2005 |
Melatonin inhibits the growth of DMBA-induced mammary tumors by decreasing the local biosynthesis of estrogens through the modulation of aromatase activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Aromatase; Aromatase Inhibitors; Carcinogens; Estrogens; Female; Mammary Neoplasms, Animal; Melatonin; Ovariectomy; Rats; Rats, Sprague-Dawley; Survival Analysis; Testosterone; Uterus | 2006 |
Lack of chemopreventive effects of alpha-eleostearic acid on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethylhydrazine (DMH)-induced mammary and colon carcinogenesis in female Sprague-Dawley rats.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Colonic Neoplasms; Diet; Dose-Response Relationship, Drug; Eating; Female; Linolenic Acids; Mammary Neoplasms, Animal; Organ Size; Plant Oils; Rats; Rats, Sprague-Dawley | 2006 |
The role of human prolactin and its antagonist, G129R, in mammary gland development and DMBA-initiated tumorigenesis in transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Female; Mammary Glands, Animal; Mammary Neoplasms, Animal; Metallothionein; Mice; Mice, Transgenic; Prolactin; Promoter Regions, Genetic | 2005 |
Enhancement by acrylamide of N-methyl-N-nitrosourea-induced rat mammary tumor development-possible application for a model to detect co-modifiers of carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acrylamide; Administration, Oral; Alkylating Agents; Animals; Carcinogens; Cell Transformation, Neoplastic; Disease Models, Animal; Drug Interactions; Female; Mammary Neoplasms, Animal; Methylnitrosourea; Nitrosamines; Rats; Rats, Sprague-Dawley; Thyroid Neoplasms | 2005 |
RelB/p52 NF-kappaB complexes rescue an early delay in mammary gland development in transgenic mice with targeted superrepressor IkappaB-alpha expression and promote carcinogenesis of the mammary gland.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Agar; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Cyclin D1; Female; Glutathione Transferase; Humans; I-kappa B Kinase; I-kappa B Proteins; Immunoblotting; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mice; Mice, Transgenic; NF-kappa B; NF-kappa B p52 Subunit; NF-KappaB Inhibitor alpha; Phenotype; Pregnancy; Pregnancy, Animal; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-myc; RNA; Time Factors; Transcription Factor RelA; Transcription Factor RelB; Transfection; Transgenes | 2005 |
Oral artemisinin prevents and delays the development of 7,12-dimethylbenz[a]anthracene (DMBA)-induced breast cancer in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Anti-Infective Agents; Artemisinins; Breast Neoplasms; Carcinogens; Chemoprevention; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Animal; Rats; Rats, Sprague-Dawley; Sesquiterpenes | 2006 |
Atm-haploinsufficiency enhances susceptibility to carcinogen-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms; Carcinogens; Cell Cycle Proteins; DNA-Binding Proteins; Environmental Pollutants; Female; Genetic Predisposition to Disease; Heterozygote; Mammary Neoplasms, Animal; Mice; Protein Serine-Threonine Kinases; Risk Factors; Signal Transduction; Survival Analysis; Tumor Suppressor Proteins | 2006 |
Transforming growth factor-beta signaling helps specify tumor type in DMBA and hormone-induced mammary cancers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Differentiation; Female; Genes, Dominant; Mammary Neoplasms, Animal; Mice; Mice, Transgenic; Myoepithelioma; Pituitary Hormones; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Signal Transduction; Transforming Growth Factor beta | 2006 |
Genetic identification of distinct loci controlling mammary tumor multiplicity, latency, and aggressiveness in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Crosses, Genetic; Female; Genotype; Male; Mammary Neoplasms, Animal; Phenotype; Quantitative Trait Loci; Quantitative Trait, Heritable; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley | 2006 |
High birth weight increases mammary tumorigenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Birth Weight; Cell Proliferation; Cell Shape; Estradiol; Female; Insulin-Like Growth Factor I; Leptin; Male; Mammary Glands, Animal; Mammary Neoplasms, Animal; Neoplasm Proteins; Pregnancy; Pregnancy Outcome; Rats; Rats, Sprague-Dawley; Risk Factors | 2006 |
Increased expression of peripheral benzodiazepine receptor (PBR) in dimethylbenz[a]anthracene-induced mammary tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzodiazepinones; Biological Transport; Blotting, Western; Carcinogens; Carrier Proteins; Cell Nucleus; Cholesterol; Female; Mammary Neoplasms, Animal; Nucleoside-Triphosphatase; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2006 |
Differentiation of spontaneous and induced mammary adenocarcinomas of the rat by gene expression profiling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Female; Gene Expression Profiling; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley | 2006 |
Mice expressing myrAKT1 in the mammary gland develop carcinogen-induced ER-positive mammary tumors that mimic human breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Breast Neoplasms; Carcinogens; Disease Models, Animal; DNA Primers; Estrogens; Female; Humans; Mammary Neoplasms, Animal; Mice; Mice, Transgenic; Myristic Acid; Proto-Oncogene Proteins c-akt | 2007 |
Obesity increases the incidence of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in an ovariectomized Zucker rat model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Female; Liver; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Obesity; Organ Size; Ovariectomy; Rats; Rats, Zucker; Time Factors | 2007 |
Breast cancer in intraductal carcinogen-treated non-human primates.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Carcinogens; Drug Administration Routes; Female; Macaca; Mammary Neoplasms, Animal | 2004 |
Green tea polyphenols reverse cooperation between c-Rel and CK2 that induces the aryl hydrocarbon receptor, slug, and an invasive phenotype.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Beverages; Carcinoma in Situ; Casein Kinase II; Female; Flavonoids; Mammary Neoplasms, Animal; Neoplasm Invasiveness; Phenols; Phenotype; Polyphenols; Proto-Oncogene Proteins c-rel; Rats; Rats, Sprague-Dawley; Snail Family Transcription Factors; Transcription Factors | 2007 |
25-Hydroxyvitamin D3 is a natural chemopreventive agent against carcinogen induced precancerous lesions in mouse mammary gland organ culture.
Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Calcifediol; Carcinogens; Chemoprevention; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mice; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroid Hydroxylases; Vitamin D3 24-Hydroxylase | 2009 |
High fish oil diet increases oxidative stress potential in mammary gland of spontaneously hypertensive rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blood Pressure; Body Weight; Diet; Fatty Acids; Female; Fish Oils; Heart Rate; Hypertension; Lipid Peroxidation; Mammary Glands, Animal; Mammary Neoplasms, Animal; Oxidative Stress; Rats; Rats, Inbred SHR | 1994 |
ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Crosses, Genetic; Ethylnitrosourea; Female; Genes, APC; Genetic Predisposition to Disease; Hyperplasia; Male; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Metaplasia; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Point Mutation | 1993 |
Fluorescence detection of tumors. Early diagnosis of microscopic lesions in preclinical studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma in Situ; Cheek; Cricetinae; Female; Fluorescence; Hematoporphyrin Derivative; Hematoporphyrin Photoradiation; Lymphatic Metastasis; Male; Mammary Neoplasms, Animal; Mice; Mice, Inbred DBA; Rats | 1993 |
Estrogen regulates vascular endothelial growth/permeability factor expression in 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Endothelial Growth Factors; Enzyme Inhibitors; Estradiol; Female; Immunohistochemistry; Lymphokines; Mammary Glands, Animal; Mammary Neoplasms, Animal; Ovariectomy; Rats; Rats, Sprague-Dawley; Reference Values; RNA, Messenger; Time Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1996 |
Prevention of mammary preneoplastic transformation by naturally-occurring tumor inhibitors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Genes, myc; Genes, ras; Hyperplasia; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mice; Precancerous Conditions; Transfection; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1997 |
Growth inhibition of DMBA-induced rat mammary carcinomas by UK 114.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antigens, Neoplasm; Complement System Proteins; Cytotoxicity, Immunologic; Female; Fluorescent Antibody Technique, Indirect; Goats; Liver; Mammary Neoplasms, Animal; Proteins; Rats; Rats, Sprague-Dawley | 1997 |
Relative contribution of calories from dietary fat, carbohydrate, and fiber in the promotion of DMBA-induced mammary tumors in Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Dietary Carbohydrates; Dietary Fats; Dietary Fiber; Energy Intake; Female; Logistic Models; Mammary Neoplasms, Animal; Rats; Rats, Sprague-Dawley | 1998 |
Regression of DMBA-induced breast carcinoma following ovariectomy is associated with increased expression of genes encoding insulin-like growth factor binding proteins.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; Female; Gene Expression; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Mammary Neoplasms, Animal; Ovariectomy; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1999 |
Soy induces phase II enzymes but does not inhibit dimethylbenz[a]anthracene-induced carcinogenesis in female rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Caseins; Diet; Dose-Response Relationship, Drug; Enzyme Induction; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Isoflavones; Liver; Mammary Neoplasms, Animal; Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Soybean Proteins; Transferases | 1999 |
Dietary fat, body weight, and cancer: contributions of studies in rodents to understanding these cancer risk factors in humans.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Dietary Fats; Female; Humans; Mammary Neoplasms, Animal; Rats; Rats, Sprague-Dawley; Risk Factors; Tea; Weight Gain | 1999 |
Three-dimensional imaging of tumor angiogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies; Disease Models, Animal; Female; Image Processing, Computer-Assisted; Immunohistochemistry; Keratins; Mammary Neoplasms, Animal; Microcirculation; Microscopy, Confocal; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Staining and Labeling | 2000 |
Chemoprevention of breast cancer in rats by celecoxib, a cyclooxygenase 2 inhibitor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Body Weight; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Ibuprofen; Isoenzymes; Mammary Neoplasms, Animal; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Substrate Specificity; Sulfonamides | 2000 |
Effects of the soluble low-molecular-mass proteins on spleen activity and cellular composition of infiltrates in rat mammary gland tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Cancer Vaccines; CD8-Positive T-Lymphocytes; Female; Ki-67 Antigen; Lymphocytes, Tumor-Infiltrating; Mammary Neoplasms, Animal; Molecular Weight; Rats; Solubility; Spleen; Splenic Neoplasms | 2001 |
Differential expression of integrin mRNAs and proteins during normal rat mammary gland development and in carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Alkylating Agents; Animals; Antigens, CD; Carcinogens; Cell Adhesion; Extracellular Matrix Proteins; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Integrin alpha5; Integrin alpha6; Integrin beta1; Integrin beta4; Mammary Glands, Animal; Mammary Neoplasms, Animal; Methylnitrosourea; Oligopeptides; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2001 |
Chemically induced rat mammary tumor treated with tamoxifen showed decreased expression of cyclin D1, cyclin E, and p21(Cip1).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Female; Gene Expression; Mammary Neoplasms, Animal; Rats; Rats, Sprague-Dawley; Tamoxifen; Treatment Outcome | 2001 |
Green tea extracts decrease carcinogen-induced mammary tumor burden in rats and rate of breast cancer cell proliferation in culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Catechin; Cell Cycle Proteins; Cell Death; Cell Division; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Female; Flavonoids; Flow Cytometry; Mammary Neoplasms, Animal; Phenols; Plant Extracts; Polymers; Probability; Rats; Tea; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2001 |
Novel esters of glaucarubolone as inducers of terminal differentiation of promyelocytic HL-60 cells and inhibitors of 7,12-dimethylbenz[a]anthracene-induced preneoplastic lesion formation in mouse mammary organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Cell Differentiation; Cell Division; Cell Membrane; DNA; Drug Screening Assays, Antitumor; Female; Glaucarubin; Glycosylation; HL-60 Cells; Humans; Inhibitory Concentration 50; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Models, Biological; Molecular Structure; Nitroblue Tetrazolium; Organ Culture Techniques; Plants, Medicinal; Quassins; Rats; Simaroubaceae; Structure-Activity Relationship; Time Factors; Tumor Cells, Cultured | 2001 |
Chemoprevention of DMBA-induced mammary cancer in rats by dietary soy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Administration, Oral; Animals; Carcinogens; Chemoprevention; Diet; Female; Mammary Neoplasms, Animal; Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Soybean Proteins | 2001 |
5-chlorodeoxycytidine, a radiosensitizer effective against RIF-1 and Lewis lung carcinoma, is also effective against a DMBA-induced mammary adenocarcinoma and the EMT-6 tumor in BALB/c mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Combined Modality Therapy; Deoxycytidine; Fibrosarcoma; Lung Neoplasms; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Radiation-Sensitizing Agents | 1992 |
Phytic acid and minerals: effect on early markers of risk for mammary and colon carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcium, Dietary; Cell Division; Chromosome Aberrations; Chromosomes; Colon; Colonic Neoplasms; Diet; DNA; Female; Iron; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mice; Mice, Inbred C57BL; Mitotic Index; Phytic Acid | 1991 |
Effects of dietary perilla oil, soybean oil and safflower oil on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethyl-hydrazine (DMH)-induced mammary gland and colon carcinogenesis in female SD rats.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenofibroma; Adenoma; alpha-Linolenic Acid; Animals; Body Weight; Carcinogens; Carcinoma, Papillary; Carcinoma, Squamous Cell; Colonic Neoplasms; Dietary Fats, Unsaturated; Dimethylhydrazines; Ear Neoplasms; Female; Linoleic Acids; Mammary Neoplasms, Animal; Methylhydrazines; Papilloma; Plant Oils; Rats; Rats, Inbred Strains; Safflower Oil; Sebaceous Gland Neoplasms; Soybean Oil | 1990 |
Additive and synergistic antitumor effects with toremifene and interferons.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Breast Neoplasms; Drug Interactions; Drug Synergism; Estrogen Antagonists; Female; Humans; Interferon Type I; Interferon-gamma; Mammary Neoplasms, Animal; Rats; Tamoxifen; Time Factors; Toremifene; Tumor Cells, Cultured | 1990 |