9-(2-hydroxy-3-nonyl)adenine has been researched along with Heart Disease, Ischemic in 16 studies
9-(2-hydroxy-3-nonyl)adenine: specific inhibitor of adenosine deaminase
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mounting evidence suggests a protective effect of exogenous adenosine in myocardial ischemia and reperfusion." | 3.68 | Augmentation of endogenous adenosine attenuates myocardial 'stunning' independently of coronary flow or hemodynamic effects. ( Abd-Elfattah, AS; Bolli, R; Jeroudi, MO; Sekili, S; Sun, JZ; Tang, XL; Zughaib, ME, 1993) |
| "Adenosine is suggested to be a potential candidate because of its high uptake and rapid intracellular sequestration." | 1.32 | Tracer adenosine: a novel myocardial flow marker. ( Deussen, A; Lauer, T; Loncar, R, 2003) |
| "Treatment with BW A1433U reduced TOIC [8." | 1.29 | Adenosine increases lactate release and delays onset of contracture during global low flow ischaemia. ( Lasley, RD; Mentzer, RM, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (81.25) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abd-Elfattah, AS | 7 |
| Tuchy, GE | 1 |
| Jessen, ME | 5 |
| Salter, DR | 1 |
| Goldstein, JP | 1 |
| Brunsting, LA | 1 |
| Wechsler, AS | 6 |
| Ding, M | 1 |
| Lauer, T | 1 |
| Loncar, R | 1 |
| Deussen, A | 1 |
| Gallagher, KP | 1 |
| McClanahan, TB | 1 |
| Martin, BJ | 1 |
| Saganek, LJ | 1 |
| Ignasiak, DP | 1 |
| Mertz, TE | 1 |
| Van Wylen, DG | 2 |
| Vinten-Johansen, J | 1 |
| Zughaib, ME | 1 |
| Jeroudi, MO | 1 |
| Sun, JZ | 1 |
| Sekili, S | 1 |
| Tang, XL | 1 |
| Bolli, R | 1 |
| Sandhu, GS | 1 |
| Burrier, AC | 1 |
| Janero, DR | 1 |
| Lasley, RD | 1 |
| Mentzer, RM | 1 |
| Xia, Y | 1 |
| Khatchikian, G | 1 |
| Zweier, JL | 1 |
| Mallet, RT | 1 |
| Lee, SC | 1 |
| Downey, HF | 1 |
| Manthei, SA | 1 |
| Reiling, CM | 1 |
| Maddox, RP | 1 |
| Rebeyka, IM | 1 |
| Lekven, J | 1 |
| Hirai, K | 1 |
| Ashraf, M | 1 |
| Schreieck, J | 1 |
| Richardt, G | 1 |
1 review available for 9-(2-hydroxy-3-nonyl)adenine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Does adenosine deaminase inhibition protect ischemic myocardium?
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Enzyme Inhibitors; Humans; In Vitro Techniques; My | 1994 |
15 other studies available for 9-(2-hydroxy-3-nonyl)adenine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Hot shot induction and reperfusion with a specific blocker of the es-ENT1 nucleoside transporter before and after hypothermic cardioplegia abolishes myocardial stunning in acutely ischemic hearts despite metabolic derangement: hot shot drug delivery befor
Topics: Adenine; Adenosine Triphosphate; Animals; Cold Ischemia; Disease Models, Animal; Dogs; Equilibrative | 2013 |
On-pump inhibition of es-ENT1 nucleoside transporter and adenosine deaminase during aortic crossclamping entraps intracellular adenosine and protects against reperfusion injury: role of adenosine A1 receptor.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Chromatography, High Pressure Liquid; Constriction | 2012 |
Tracer adenosine: a novel myocardial flow marker.
Topics: Adenine; Adenosine; Alprostadil; Animals; Carbon Radioisotopes; Coronary Circulation; Dogs; Isotope | 2003 |
Nucleoside trapping during reperfusion prevents ventricular dysfunction, "stunning," in absence of adenosine. Possible separation between ischemic and reperfusion injury.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Affinity Labels; Animals; B | 1994 |
Separation between ischemic and reperfusion injury by site specific entrapment of endogenous adenosine and inosine using NBMPR and EHNA.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Dogs; Female; Heart; Inosi | 1994 |
Augmentation of endogenous adenosine attenuates myocardial 'stunning' independently of coronary flow or hemodynamic effects.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Coronary Circulation; Dogs; Heart; Hemodynamics; M | 1993 |
Adenosine deaminase inhibitors attenuate ischemic injury and preserve energy balance in isolated guinea pig heart.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Coformycin; Creatine Kinase; Energy Metabolism; Gu | 1993 |
Adenosine increases lactate release and delays onset of contracture during global low flow ischaemia.
Topics: Adenine; Adenosine; Animals; Glucose; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardia | 1993 |
Adenosine deaminase inhibition prevents free radical-mediated injury in the postischemic heart.
Topics: Adenine; Adenine Nucleotides; Adenosine Deaminase Inhibitors; Animals; Coronary Circulation; Electro | 1996 |
Endogenous adenosine increases O2 utilisation efficiency in isoprenaline-stimulated canine myocardium.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adrenergic beta-Agonists; Animals; Dogs; Hypoxia; Isoproter | 1996 |
Dual cardiac microdialysis to assess drug-induced changes in interstitial purine metabolites: adenosine deaminase inhibition versus adenosine kinase inhibition.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Chromatography, High | 1998 |
Role of nucleoside transport and purine release in a rabbit model of myocardial stunning.
Topics: Adenine; Adenine Nucleotides; Adenosine Deaminase Inhibitors; Animals; Carrier Proteins; Dogs; Enzym | 1998 |
Differential cardioprotection with selective inhibitors of adenosine metabolism and transport: role of purine release in ischemic and reperfusion injury.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Carrier Proteins; | 1998 |
Modulation of adenosine effects in attenuation of ischemia and reperfusion injury in rat heart.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Enzyme Inhibitors; Heart; Heart Rate; I | 1998 |
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiogra | 1999 |