9-(2-hydroxy-3-nonyl)adenine has been researched along with Disease Models, Animal in 10 studies
9-(2-hydroxy-3-nonyl)adenine: specific inhibitor of adenosine deaminase
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In order to further evaluate the role of adenosine in seizure activity, we monitored adenosine and its major biochemical metabolites inosine, xanthine, and hypoxanthine in the dorsal hippocampus by in vivo microdialysis before and during the induction of generalized seizures." | 7.70 | Evidence for increased dorsal hippocampal adenosine release and metabolism during pharmacologically induced seizures in rats. ( Aden, U; Berman, RF; Fredholm, BB; O'Connor, WT, 2000) |
| "Our previous studies demonstrated that the topical application of caffeine is a potent inhibitor of UVB-induced carcinogenesis and selectively increases apoptosis in tumors but not in non-tumor areas of the epidermis in mice that are at a high risk for developing skin cancer." | 3.80 | PDE2 is a novel target for attenuating tumor formation in a mouse model of UVB-induced skin carcinogenesis. ( Bernard, JJ; Li, T; Lou, YR; Lu, YP; Peng, QY, 2014) |
| " In order to further evaluate the role of adenosine in seizure activity, we monitored adenosine and its major biochemical metabolites inosine, xanthine, and hypoxanthine in the dorsal hippocampus by in vivo microdialysis before and during the induction of generalized seizures." | 3.70 | Evidence for increased dorsal hippocampal adenosine release and metabolism during pharmacologically induced seizures in rats. ( Aden, U; Berman, RF; Fredholm, BB; O'Connor, WT, 2000) |
| "Adenosine is an important neuromodulator, that has been indicated to be affected by acute and chronic exposure to ethanol." | 1.56 | Inhibition of ecto-5'-nucleotidase and adenosine deaminase is able to reverse long-term behavioural effects of early ethanol exposure in zebrafish (Danio rerio). ( Da Silva, RS; Lutte, AH; Majolo, JH, 2020) |
| "Colitis was associated with decreased food intake and body weight, augmented spleen weight, and increased levels of colonic TNF-α, IL-6, and MDA." | 1.36 | The blockade of adenosine deaminase ameliorates chronic experimental colitis through the recruitment of adenosine A2A and A3 receptors. ( Antonioli, L; Awwad, O; Blandizzi, C; Colucci, R; Da Settimo, F; Duranti, E; Fornai, M; Ghisu, N; La Motta, C; Natale, G; Tuccori, M; Virdis, A, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lutte, AH | 1 |
| Majolo, JH | 1 |
| Da Silva, RS | 1 |
| Abd-Elfattah, AS | 2 |
| Tuchy, GE | 1 |
| Jessen, ME | 2 |
| Salter, DR | 1 |
| Goldstein, JP | 1 |
| Brunsting, LA | 1 |
| Wechsler, AS | 2 |
| Bernard, JJ | 1 |
| Lou, YR | 1 |
| Peng, QY | 1 |
| Li, T | 2 |
| Lu, YP | 1 |
| Bortolotto, JW | 1 |
| Melo, GM | 1 |
| Cognato, Gde P | 1 |
| Vianna, MR | 1 |
| Bonan, CD | 1 |
| Kommajosyula, SP | 1 |
| Randall, ME | 1 |
| Faingold, CL | 1 |
| Shen, HY | 1 |
| Boison, D | 1 |
| Antonioli, L | 1 |
| Fornai, M | 1 |
| Colucci, R | 1 |
| Awwad, O | 1 |
| Ghisu, N | 1 |
| Tuccori, M | 1 |
| Da Settimo, F | 1 |
| La Motta, C | 1 |
| Natale, G | 1 |
| Duranti, E | 1 |
| Virdis, A | 1 |
| Blandizzi, C | 1 |
| Ding, M | 1 |
| Berman, RF | 1 |
| Fredholm, BB | 1 |
| Aden, U | 1 |
| O'Connor, WT | 1 |
| Keeling, IM | 1 |
| Obermayr, RP | 1 |
| Schneider, B | 1 |
| Spieckermann, PG | 1 |
10 other studies available for 9-(2-hydroxy-3-nonyl)adenine and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of ecto-5'-nucleotidase and adenosine deaminase is able to reverse long-term behavioural effects of early ethanol exposure in zebrafish (Danio rerio).
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Animals; | 2020 |
Hot shot induction and reperfusion with a specific blocker of the es-ENT1 nucleoside transporter before and after hypothermic cardioplegia abolishes myocardial stunning in acutely ischemic hearts despite metabolic derangement: hot shot drug delivery befor
Topics: Adenine; Adenosine Triphosphate; Animals; Cold Ischemia; Disease Models, Animal; Dogs; Equilibrative | 2013 |
PDE2 is a novel target for attenuating tumor formation in a mouse model of UVB-induced skin carcinogenesis.
Topics: Adenine; Animals; Apoptosis; Caffeine; Carcinogenesis; Cyclic Nucleotide Phosphodiesterases, Type 2; | 2014 |
Modulation of adenosine signaling prevents scopolamine-induced cognitive impairment in zebrafish.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Avoidance Learning; Cognition Disorders | 2015 |
Inhibition of adenosine metabolism induces changes in post-ictal depression, respiration, and mortality in genetically epilepsy prone rats.
Topics: Adenine; Adenosine; Animals; Blood Gas Analysis; Brugada Syndrome; Disease Models, Animal; Enzyme In | 2016 |
A novel mouse model for sudden unexpected death in epilepsy (SUDEP): role of impaired adenosine clearance.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Caffeine; Cause of De | 2010 |
The blockade of adenosine deaminase ameliorates chronic experimental colitis through the recruitment of adenosine A2A and A3 receptors.
Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Blotting, Western; Body Weigh | 2010 |
On-pump inhibition of es-ENT1 nucleoside transporter and adenosine deaminase during aortic crossclamping entraps intracellular adenosine and protects against reperfusion injury: role of adenosine A1 receptor.
Topics: Adenine; Adenosine Deaminase Inhibitors; Animals; Chromatography, High Pressure Liquid; Constriction | 2012 |
Evidence for increased dorsal hippocampal adenosine release and metabolism during pharmacologically induced seizures in rats.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Bicuculline; Convulsants; Disease Model | 2000 |
Postischemic cardiac function recovery in the isolated rat heart: effects of adenosine deaminase and nucleoside transport inhibition.
Topics: Adenine; Adenosine Deaminase; Affinity Labels; Animals; Cardioplegic Solutions; Disease Models, Anim | 2000 |