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9-(2-hydroxy-3-nonyl)adenine and Colitis

9-(2-hydroxy-3-nonyl)adenine has been researched along with Colitis in 3 studies

9-(2-hydroxy-3-nonyl)adenine: specific inhibitor of adenosine deaminase

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
"Colitis was induced by 2,4-dinitrobenzenesulfonic acid (DNBS)."3.80Role of the A(2B) receptor-adenosine deaminase complex in colonic dysmotility associated with bowel inflammation in rats. ( Antonioli, L; Awwad, O; Blandizzi, C; Brun, P; Caputi, V; Castagliuolo, I; Colucci, R; Fornai, M; Giron, MC; Giustarini, G; Pellegrini, C; Qesari, M; Scarpignato, C; Tuccori, M, 2014)
" In this study, the effects of 4-amino-2-(2-hydroxy-1-decyl)pyrazole[3,4-d]pyrimidine (APP; novel adenosine deaminase inhibitor), erythro-9-(2-hydroxy-3-nonyl)adenine hydrochloride (EHNA; standard adenosine deaminase inhibitor), and dexamethasone were tested in rats with colitis induced by 2,4-dinitrobenzenesulfonic acid (DNBS)."3.74Inhibition of adenosine deaminase attenuates inflammation in experimental colitis. ( Antonioli, L; Blandizzi, C; Breschi, MC; Colucci, R; Da Settimo, F; Del Taca, M; Duranti, E; Fornai, M; Ghisu, N; Kastsiuchenka, O; La Motta, C; Mugnaini, L; Natale, G; Vassalle, C; Virdis, A, 2007)
"Colitis was associated with decreased food intake and body weight, augmented spleen weight, and increased levels of colonic TNF-α, IL-6, and MDA."1.36The blockade of adenosine deaminase ameliorates chronic experimental colitis through the recruitment of adenosine A2A and A3 receptors. ( Antonioli, L; Awwad, O; Blandizzi, C; Colucci, R; Da Settimo, F; Duranti, E; Fornai, M; Ghisu, N; La Motta, C; Natale, G; Tuccori, M; Virdis, A, 2010)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Antonioli, L3
Fornai, M3
Awwad, O2
Giustarini, G1
Pellegrini, C1
Tuccori, M2
Caputi, V1
Qesari, M1
Castagliuolo, I1
Brun, P1
Giron, MC1
Scarpignato, C1
Blandizzi, C3
Colucci, R3
Ghisu, N2
Da Settimo, F2
La Motta, C2
Natale, G2
Duranti, E2
Virdis, A2
Kastsiuchenka, O1
Vassalle, C1
Mugnaini, L1
Breschi, MC1
Del Taca, M1

Other Studies

3 other studies available for 9-(2-hydroxy-3-nonyl)adenine and Colitis

ArticleYear
Role of the A(2B) receptor-adenosine deaminase complex in colonic dysmotility associated with bowel inflammation in rats.
    British journal of pharmacology, 2014, Volume: 171, Issue:5

    Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Benzenesulfonates; Colitis; C

2014
The blockade of adenosine deaminase ameliorates chronic experimental colitis through the recruitment of adenosine A2A and A3 receptors.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 335, Issue:2

    Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Blotting, Western; Body Weigh

2010
Inhibition of adenosine deaminase attenuates inflammation in experimental colitis.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:2

    Topics: Adenine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Benzenesulfonates; Body Weigh

2007