9-(2--hydroxyethylamino)-4-methyl-1-nitroacridine has been researched along with Pancreatic-Neoplasms* in 1 studies
1 other study(ies) available for 9-(2--hydroxyethylamino)-4-methyl-1-nitroacridine and Pancreatic-Neoplasms
Article | Year |
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The overexpression of CPR and P450 3A4 in pancreatic cancer cells changes the metabolic profile and increases the cytotoxicity and pro-apoptotic activity of acridine antitumor agent, C-1748.
Topics: Antineoplastic Agents; Apoptosis; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP3A; Drug Resistance, Neoplasm; Flow Cytometry; Gene Expression; Humans; Membrane Potential, Mitochondrial; NADPH-Ferrihemoprotein Reductase; Nitracrine; Pancreatic Neoplasms; Transfection; Up-Regulation | 2017 |