Compounds > 9-(2-(phosphonomethoxy)ethyl)adenine-diphosphate

9-(2-(phosphonomethoxy)ethyl)adenine-diphosphate and HIV-Infections

9-(2-(phosphonomethoxy)ethyl)adenine-diphosphate has been researched along with HIV-Infections* in 1 studies

Other Studies

1 other study(ies) available for 9-(2-(phosphonomethoxy)ethyl)adenine-diphosphate and HIV-Infections

Article	Year
Design, synthesis and anti-HIV activity of homologous PMEA derivatives. Nucleosides, nucleotides & nucleic acids, 2008, Volume: 27, Issue:2 This article describes an efficient route for synthesizing novel cyclopropyl homologous PMEA analogues. The condensation of the bromide 8 with nucleosidic bases (A, U, T, C, 5-FU, G) under standard nucleophilic substitution and deprotection conditions, afforded the target phosphonic acid analogues 14 approximately 18 and 21. These compounds were evaluated for their potential antiviral properties against various viruses. Guanine derivative 21 showed significant antiviral activity. Topics: Adenine; Anti-HIV Agents; Drug Design; HIV Infections; HIV-1; Humans	2008

Article

Year

Design, synthesis and anti-HIV activity of homologous PMEA derivatives.

Nucleosides, nucleotides & nucleic acids, 2008, Volume: 27, Issue:2

This article describes an efficient route for synthesizing novel cyclopropyl homologous PMEA analogues. The condensation of the bromide 8 with nucleosidic bases (A, U, T, C, 5-FU, G) under standard nucleophilic substitution and deprotection conditions, afforded the target phosphonic acid analogues 14 approximately 18 and 21. These compounds were evaluated for their potential antiviral properties against various viruses. Guanine derivative 21 showed significant antiviral activity.

Topics: Adenine; Anti-HIV Agents; Drug Design; HIV Infections; HIV-1; Humans

2008