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8-phenyltheophylline and Muscle Relaxation

8-phenyltheophylline has been researched along with Muscle Relaxation in 27 studies

8-phenyltheophylline: purinergic P1 receptor antagonist

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
" The effects of NG-monomethyl-L-arginine, tetrodotoxin and glibenclamide on hypoxia-induced coronary artery relaxation, induced by bubbling Krebs solution with 95% N2 and 5% CO2 instead of 95% O2 and 5% CO2, were assessed by measuring the changes in isometric tension in isolated epicardial coronary artery rings of the rabbit."7.69Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide. ( Collins, P; Jiang, C, 1994)
"Adenosine pretreatment (3."5.27Cellular Ca2+ monitored by aequorin in adenosine-mediated smooth muscle relaxation. ( Bradley, AB; Morgan, KG, 1985)
" The effects of NG-monomethyl-L-arginine, tetrodotoxin and glibenclamide on hypoxia-induced coronary artery relaxation, induced by bubbling Krebs solution with 95% N2 and 5% CO2 instead of 95% O2 and 5% CO2, were assessed by measuring the changes in isometric tension in isolated epicardial coronary artery rings of the rabbit."3.69Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide. ( Collins, P; Jiang, C, 1994)
" Dose-response data for both agonists were best represented by two-site models."1.29A biphasic response to adenosine in the coronary vasculature of the K(+)-arrested perfused rat heart. ( Harden, FA; Harrison, GJ; Headrick, J; Jordan, LR; Willis, RJ, 1996)
"Adenosine pretreatment (3."1.27Cellular Ca2+ monitored by aequorin in adenosine-mediated smooth muscle relaxation. ( Bradley, AB; Morgan, KG, 1985)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199012 (44.44)18.7374
1990's14 (51.85)18.2507
2000's1 (3.70)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tasatargil, A1
Sadan, G2
Ozdem, SS1
Collis, MG3
Brown, CM1
Prentice, DJ1
Shankley, NP1
Black, JW1
Tsunoda, R1
Okumura, K1
Ishizaka, H1
Matsunaga, T1
Tabuchi, T1
Yasue, H1
Akaike, T1
Sato, K1
Maeda, H1
Jiang, C1
Collins, P1
Vuorinen, P1
Wu, X1
Arvola, P1
Vapaatalo, H1
Pörsti, I1
Boland, B1
Himpens, B1
Paques, C1
Casteels, R1
Gillis, JM1
Fedan, JS1
Belt, JJ1
Yuan, LX1
Frazer, DG1
Nicholls, J1
Brownhill, VR1
Hourani, SM2
Harden, FA1
Harrison, GJ1
Headrick, J1
Jordan, LR1
Willis, RJ1
Kaputlu, I1
Hernández, M1
Barahona, MV1
Bustamante, S1
García-Sacristán, A1
Orensanz, LM1
Chinellato, A1
Ragazzi, E1
Pandolfo, L1
Froldi, G1
Caparrotta, L1
Fassina, G1
Koga, T1
Takata, Y1
Kobayashi, K1
Fujii, K1
Nagao, T1
Fujishima, M1
Sabouni, MH1
Brown, GL1
Kotake, AN1
Douglas, FL1
Mustafa, SJ3
Rose'Meyer, RB1
Hope, W1
Furukawa, K1
Nomoto, T1
Stoggall, SM1
Martin, FM1
Manzini, S1
Maggi, CA1
Meli, A1
Nakagawa, Y1
Gudenzi, M1
Gaion, RM2
Dorigo, P2
Trolese, B1
Borin, E1
Adami, R1
Gambarotto, L1
Welford, LA1
Loizou, GD1
Cusak, NJ1
Ceroni, G1
Giacometti, A1
Valentini, E1
Maragno, I1
Achterrath-Tuckermann, U1
Szelenyi, I1
Askar, AO1
Palmer, DB1
Baxter, GS1
Bradley, AB1
Morgan, KG1

Other Studies

27 other studies available for 8-phenyltheophylline and Muscle Relaxation

ArticleYear
The effects of selective phosphodiesterase III and V inhibitors on adrenergic and non-adrenergic, non-cholinergic relaxation responses of guinea-pig pulmonary arteries.
    Autonomic & autacoid pharmacology, 2003, Volume: 23, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Animals; Argini

2003
Adenosine relaxes the aorta by interacting with an A2 receptor and an intracellular site.
    European journal of pharmacology, 1983, Dec-09, Volume: 96, Issue:1-2

    Topics: Adenosine; Animals; Aorta; Dipyridamole; Drug Interactions; Female; Guinea Pigs; In Vitro Techniques

1983
Pharmacological analysis of the interaction between purinoceptor agonists and antagonists in the guinea-pig taenia caecum.
    British journal of pharmacology, 1995, Volume: 115, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cecum; Dipyridamole; Do

1995
Vasodilator effect of carboxy-2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl in the coronary circulation: in vivo and in vitro studies.
    European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2

    Topics: Animals; Arginine; Benzoates; Blood Pressure; Coronary Circulation; Cyclic N-Oxides; Dogs; Dose-Resp

1994
Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide.
    British journal of pharmacology, 1994, Volume: 111, Issue:3

    Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Capsaicin; Coronary Vessels; Endothelium, Vasc

1994
Effects of P1 and P2Y purinoceptor antagonists on endothelium-dependent and -independent relaxations of rat mesenteric artery to GTP and guanosine.
    British journal of pharmacology, 1994, Volume: 112, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Animals; Endothelium, Vascular; Guanosine; Guanosine Triphosphate

1994
ATP induced-relaxation in the mouse bladder smooth muscle.
    British journal of pharmacology, 1993, Volume: 108, Issue:3

    Topics: Adenosine Triphosphate; Animals; Calcium; Cytosol; Electric Stimulation; Fura-2; In Vitro Techniques

1993
Relaxant effects of nucleotides in guinea pig isolated, perfused trachea: lack of involvement of prostanoids, Cl- channels and adenosine.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:1

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo

1993
Characterization of P1-purinoceptors on rat isolated duodenum longitudinal muscle and muscularis mucosae.
    British journal of pharmacology, 1996, Volume: 117, Issue:1

    Topics: Adenosine; Animals; Duodenum; Male; Muscle Relaxation; Muscle, Smooth; Rats; Receptors, Purinergic P

1996
A biphasic response to adenosine in the coronary vasculature of the K(+)-arrested perfused rat heart.
    European journal of pharmacology, 1996, Jun-20, Volume: 307, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Coronary Vessels; Hea

1996
Evidence that nitric oxide mediates non-adrenergic non-cholinergic relaxation induced by GABA and electrical stimulation in the rat isolated duodenum.
    Journal of autonomic pharmacology, 1996, Volume: 16, Issue:4

    Topics: Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; E

1996
A2B adenosine receptors mediate relaxation of the pig intravesical ureter: adenosine modulation of non adrenergic non cholinergic excitatory neurotransmission.
    British journal of pharmacology, 1999, Volume: 126, Issue:4

    Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Dose-Response Relatio

1999
Pharmacological characterization of a new purinergic receptor site in rabbit aorta.
    General pharmacology, 1992, Volume: 23, Issue:6

    Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta, Thoracic; In Vitro Techniques; Male; Muscle Relax

1992
Age-related changes in P2-purinergic receptors on vascular smooth muscle and endothelium.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:3

    Topics: Adenosine Triphosphate; Aging; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascul

1992
Effects of CGS-15943A on the relaxations produced by adenosine analogs in human blood vessels.
    European journal of pharmacology, 1990, Oct-23, Volume: 187, Issue:3

    Topics: Adenosine; Adult; Coronary Vessels; Humans; In Vitro Techniques; Mammary Arteries; Middle Aged; Musc

1990
Evidence that A2 purinoceptors are involved in endothelium-dependent relaxation of the rat thoracic aorta.
    British journal of pharmacology, 1990, Volume: 100, Issue:3

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals

1990
Postnatal changes in response to adenosine and adenine nucleotides in rat duodenum.
    British journal of pharmacology, 1989, Volume: 97, Issue:4

    Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Duodenum; Female;

1989
Apparent affinity of 1,3-dipropyl-8-cyclopentylxanthine for adenosine A1 and A2 receptors in isolated tissues from guinea-pigs.
    British journal of pharmacology, 1989, Volume: 97, Issue:4

    Topics: Adenosine; Animals; Aorta, Thoracic; Binding, Competitive; Guinea Pigs; Heart Rate; In Vitro Techniq

1989
Further evidence for involvement of adenosine-5'-triphosphate in non-adrenergic non-cholinergic relaxation of the isolated rat duodenum.
    European journal of pharmacology, 1985, Jul-31, Volume: 113, Issue:3

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Autonomi

1985
Calcium entry blocking activity of dilazep in dog coronary artery.
    Pharmacology, 1986, Volume: 33, Issue:3

    Topics: Adenine; Adenosine; Adenosine Deaminase; Animals; Arteries; Azepines; Calcium; Calcium Channel Block

1986
Involvement of P1-purinoreceptors in the relaxing effect of adenosine in rat duodenum.
    Journal of autonomic pharmacology, 1988, Volume: 8, Issue:2

    Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Duodenum; In Vitro Techniques; Male; Muscle Co

1988
Adenosine 5'-(2-fluorodiphosphate) is a selective agonist at P2-purinoceptors mediating relaxation of smooth muscle.
    European journal of pharmacology, 1988, Feb-16, Volume: 147, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Aorta, Thoracic; Colon; Guinea Pigs; In Vitr

1988
The response of isolated guinea-pig aorta to amrinone.
    Journal of autonomic pharmacology, 1988, Volume: 8, Issue:1

    Topics: Adenosine; Adenosine Deaminase; Amrinone; Animals; Aorta, Thoracic; Female; Guinea Pigs; In Vitro Te

1988
Interaction of azelastine with adenosine receptors in guinea pig trachea.
    Agents and actions, 1988, Volume: 23, Issue:3-4

    Topics: Animals; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Phenylisopropyladenosine; Phthal

1988
Effect of calcium entry blockers and adenosine on the relaxation of large and small coronary arteries.
    Life sciences, 1986, Mar-10, Volume: 38, Issue:10

    Topics: Adenosine; Animals; Arteries; Calcium Channel Blockers; Cattle; Coronary Vessels; Dose-Response Rela

1986
Evidence that the intracellular effects of adenosine in the guinea-pig aorta are mediated by inosine.
    European journal of pharmacology, 1986, Feb-11, Volume: 121, Issue:1

    Topics: Adenosine; Animals; Aorta, Thoracic; Female; Guinea Pigs; In Vitro Techniques; Inosine; Male; Muscle

1986
Cellular Ca2+ monitored by aequorin in adenosine-mediated smooth muscle relaxation.
    The American journal of physiology, 1985, Volume: 248, Issue:1 Pt 2

    Topics: Adenosine; Aequorin; Animals; Body Fluids; Calcium; Dose-Response Relationship, Drug; Electric Stimu

1985