8-phenyltheophylline has been researched along with Muscle Contraction in 38 studies
8-phenyltheophylline: purinergic P1 receptor antagonist
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adenosine pretreatment (3." | 5.27 | Cellular Ca2+ monitored by aequorin in adenosine-mediated smooth muscle relaxation. ( Bradley, AB; Morgan, KG, 1985) |
| " The adenosine receptor antagonist 8-(p-sulphophenyl)theophylline (8-SPT, 50 microM) produced approximately 50 fold shifts of the dose-response curves to adenosine, AMP and AMPPCP, whereas those to ATP, MeSATP and substance P (SP) were unaffected." | 1.28 | A study of the purinoceptors mediating contraction in the rat colon. ( Bailey, SJ; Hourani, SM, 1990) |
| "adenosine were significantly less than -1 unless the adenosine reuptake blocker dipyridamole (0." | 1.27 | Effects of caffeine and 8-phenyltheophylline on the actions of purines and opiates in the guinea-pig ileum. ( Ahlijanian, MK; Takemori, AE, 1986) |
| "Adenosine pretreatment (3." | 1.27 | Cellular Ca2+ monitored by aequorin in adenosine-mediated smooth muscle relaxation. ( Bradley, AB; Morgan, KG, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (55.26) | 18.7374 |
| 1990's | 16 (42.11) | 18.2507 |
| 2000's | 1 (2.63) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ghildyal, P | 1 |
| Palani, D | 1 |
| Manchanda, R | 1 |
| Collier, HO | 2 |
| Tucker, JF | 2 |
| Sneddon, P | 2 |
| Meldrum, LA | 1 |
| Burnstock, G | 5 |
| Collis, MG | 2 |
| Brown, CM | 1 |
| Hills, JM | 1 |
| Hoyle, CH | 1 |
| Kennedy, C | 1 |
| Griffith, SG | 1 |
| Meghji, P | 1 |
| Moody, CJ | 1 |
| Prentice, DJ | 1 |
| Shankley, NP | 1 |
| Black, JW | 1 |
| Takaki, M | 1 |
| Namba, T | 1 |
| Fujii, W | 1 |
| Suga, H | 1 |
| Reeves, JJ | 1 |
| Jarvis, JE | 1 |
| Sheehan, MJ | 1 |
| Strong, P | 1 |
| Duncker, DJ | 1 |
| van Zon, NS | 1 |
| Pavek, TJ | 1 |
| Herrlinger, SK | 1 |
| Bache, RJ | 1 |
| Boland, B | 1 |
| Himpens, B | 1 |
| Paques, C | 1 |
| Casteels, R | 1 |
| Gillis, JM | 1 |
| Orito, K | 1 |
| Satoh, K | 1 |
| Taira, N | 1 |
| Poucher, SM | 2 |
| Yang, XP | 1 |
| Chiba, S | 1 |
| Dehpour, AR | 1 |
| Vazifehshenas, F | 1 |
| Acevedo, CG | 1 |
| Contreras, E | 1 |
| Escalona, J | 1 |
| Lewin, J | 1 |
| Huidobro-Toro, JP | 1 |
| Nagano, O | 1 |
| Földes, FF | 1 |
| Nakatsuka, H | 1 |
| Reich, D | 1 |
| Ohta, Y | 1 |
| Sperlagh, B | 1 |
| Vizi, ES | 1 |
| Bailey, SJ | 1 |
| Hourani, SM | 1 |
| Brizzolara, AL | 1 |
| Lynch, M | 1 |
| Huddart, H | 1 |
| Serio, R | 1 |
| Mulè, F | 1 |
| Adamo, EB | 1 |
| Postorino, A | 1 |
| Nowell, CG | 1 |
| Sebastião, AM | 1 |
| Ribeiro, JA | 2 |
| De Mendonça, A | 1 |
| Muramatsu, I | 1 |
| Ohmura, T | 1 |
| Oshita, M | 1 |
| Furukawa, K | 1 |
| Nomoto, T | 1 |
| Dalziel, HH | 1 |
| Fuglsang, A | 1 |
| Crone, C | 1 |
| Ahlijanian, MK | 1 |
| Takemori, AE | 1 |
| Frew, R | 1 |
| Lundy, PM | 1 |
| Gaion, RM | 1 |
| Dorigo, P | 1 |
| Trolese, B | 1 |
| Borin, E | 1 |
| Adami, R | 1 |
| Gambarotto, L | 1 |
| Kurokawa, M | 1 |
| Tsunoo, A | 1 |
| Amobi, N | 1 |
| Smith, IC | 1 |
| Chiou, LC | 1 |
| Hong, SJ | 1 |
| Chang, CC | 1 |
| Mustafa, SJ | 1 |
| Askar, AO | 1 |
| Bradley, AB | 1 |
| Morgan, KG | 1 |
1 review available for 8-phenyltheophylline and Muscle Contraction
| Article | Year |
|---|---|
Sites and mechanisms of dependence in the myenteric plexus of guinea pig ileum.
Topics: Acetylcholine; Adenosine; Animals; Clonidine; Cyclic AMP; Guinea Pigs; Humans; Ileum; In Vitro Techn | 1984 |
37 other studies available for 8-phenyltheophylline and Muscle Contraction
| Article | Year |
|---|---|
Post- and prejunctional consequences of ecto-ATPase inhibition: electrical and contractile studies in guinea-pig vas deferens.
Topics: Action Potentials; Adenosine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Electrophy | 2006 |
Control of transmitter release in guinea-pig vas deferens by prejunctional P1-purinoceptors.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Triphosphate; Animals; Dipyridamole; Electric Stimu | 1984 |
Adenosine relaxes the aorta by interacting with an A2 receptor and an intracellular site.
Topics: Adenosine; Animals; Aorta; Dipyridamole; Drug Interactions; Female; Guinea Pigs; In Vitro Techniques | 1983 |
Evidence that the P1-purinoceptor in the guinea-pig taenia coli is an A2-subtype.
Topics: Adenosine; Animals; Colon; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Cont | 1984 |
Evidence for an inhibitory prejunctional P1-purinoceptor in the rat portal vein with characteristics of the A2 rather than of the A1 subtype.
Topics: Adenosine; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smo | 1984 |
Novel form of drug-dependence--on adenosine in guinea pig ileum.
Topics: Adenosine; Animals; Caffeine; Guinea Pigs; Humans; Ileum; Morphine Derivatives; Muscle Contraction; | 1983 |
8-phenyltheophylline: a potent P1-purinoceptor antagonist.
Topics: Adenosine; Animals; Basilar Artery; Female; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Ma | 1981 |
Pharmacological analysis of the interaction between purinoceptor agonists and antagonists in the guinea-pig taenia caecum.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cecum; Dipyridamole; Do | 1995 |
Adenosine inhibits efferent function of extrinsic capsaicin-sensitive sensory nerves in the enteric nervous system.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Adenosine; Animals; Capsaicin; Electric Stimulation; Ele | 1993 |
Further investigations into adenosine A1 receptor-mediated contraction in rat colonic muscularis mucosae and its augmentation by certain alkylxanthine antagonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colon; Cyclooxygenase Inhibitors; In Vitro Te | 1995 |
Endogenous adenosine mediates coronary vasodilation during exercise after K(ATP)+ channel blockade.
Topics: Adenosine; Animals; Coronary Circulation; Diastole; Dogs; Glyburide; Guanidines; Hemodynamics; Hyper | 1995 |
ATP induced-relaxation in the mouse bladder smooth muscle.
Topics: Adenosine Triphosphate; Animals; Calcium; Cytosol; Electric Stimulation; Fura-2; In Vitro Techniques | 1993 |
Involvement of ATP-sensitive K+ channels in the sustained coronary vasodilator response to adenosine in dogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Dogs; Female; Gl | 1993 |
Muscle contraction-induced steal model in the anesthetized cat.
Topics: Anesthesia; Animals; Arteries; Blood Gas Analysis; Blood Pressure Determination; Cats; Electric Stim | 1998 |
Adrenergic-purinergic interactions on vasoconstrictor responses to periarterial electric nerve stimulation in canine splenic arteries.
Topics: Adenosine Triphosphate; Animals; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Musc | 1999 |
Rabbit isolated vas deferens possess A1 and A2 adenosine receptors.
Topics: Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purine | 1992 |
Pharmacological characterization of adenosine A1 and A2 receptors in the bladder: evidence for a modulatory adenosine tone regulating non-adrenergic non-cholinergic neurotransmission.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Autonomic Nervous Sys | 1992 |
Presynaptic A1-purinoceptor-mediated inhibitory effects of adenosine and its stable analogues on the mouse hemidiaphragm preparation.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diaphragm; | 1992 |
A study of the purinoceptors mediating contraction in the rat colon.
Topics: Adenosine; Animals; Colon; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purines; R | 1990 |
Endothelium-dependent and endothelium-independent vasodilatation of the hepatic artery of the rabbit.
Topics: Animals; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Hepatic Artery; Immunohistochemistr | 1991 |
Purinergic modulation of field stimulation responses of rat and human vas deferens smooth muscle.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Electric St | 1991 |
Evidence against purines being neurotransmitters of non-adrenergic, non-cholinergic nerves in rat duodenum.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Autonomi | 1990 |
The role of adenosine in exercise hyperaemia of the gracilis muscle in anaesthetized cats.
Topics: Adenosine; Animals; Cats; Hyperemia; Leg; Muscle Contraction; Muscles; Physical Exertion; Regional B | 1990 |
On the adenosine receptor and adenosine inactivation at the rat diaphragm neuromuscular junction.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Diaphragm; Evoked Potentials; Fe | 1988 |
Diazepam enhances the inhibitory action of adenosine on transmission at the frog neuromuscular junction.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diazepam; Dipyridamole; Drug Synergism; In Vi | 1989 |
Comparison between sympathetic adrenergic and purinergic transmission in the dog mesenteric artery.
Topics: Adenosine Triphosphate; Animals; Cocaine; Dogs; Female; Imidazoles; In Vitro Techniques; Male; Mesen | 1989 |
Postnatal changes in response to adenosine and adenine nucleotides in rat duodenum.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Duodenum; Female; | 1989 |
The mechanism of action of AMP-induced inhibition of sympathetic neurotransmission in the isolated vas deferens of the rat and guinea-pig.
Topics: Action Potentials; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro T | 1988 |
Presynaptic inhibition of sympathetic fibers participating in vasodilatation in response to K+-induced contraction of frog skeletal muscle.
Topics: Adenosine; Animals; Arterioles; Biological Transport; Dipyridamole; Muscle Contraction; Muscle, Smoo | 1988 |
Effects of caffeine and 8-phenyltheophylline on the actions of purines and opiates in the guinea-pig ileum.
Topics: Adenosine; Animals; Caffeine; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contra | 1986 |
Arylazido aminopropionyl ATP (ANAPP3): interaction with adenosine receptors in longitudinal smooth muscle of the guinea-pig ileum.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Azides; Electric Stimulation; Guine | 1986 |
Involvement of P1-purinoreceptors in the relaxing effect of adenosine in rat duodenum.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Duodenum; In Vitro Techniques; Male; Muscle Co | 1988 |
Parasympathetic depression of vas deferens contraction in the guinea-pig involves adenosine receptors.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Mal | 1988 |
Effects of alpha,beta-methylene ATP on biphasic responses of rat vas deferens.
Topics: Adenosine Triphosphate; Animals; Dioxanes; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; | 1987 |
Does endogenous adenosine modulate the release of acetylcholine from motor nerve during single and repetitive stimulations in the mouse diaphragm?
Topics: Acetylcholine; Adenosine; Animals; Dipyridamole; Electric Stimulation; In Vitro Techniques; Membrane | 1987 |
Effect of calcium entry blockers and adenosine on the relaxation of large and small coronary arteries.
Topics: Adenosine; Animals; Arteries; Calcium Channel Blockers; Cattle; Coronary Vessels; Dose-Response Rela | 1986 |
Cellular Ca2+ monitored by aequorin in adenosine-mediated smooth muscle relaxation.
Topics: Adenosine; Aequorin; Animals; Body Fluids; Calcium; Dose-Response Relationship, Drug; Electric Stimu | 1985 |